# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- MAGE_N PF12440.8 RJW59556.1 - 7.3 7.3 12.3 26 5.6 12.4 1.9 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal DUF1682 PF07946.14 RJW59558.1 - 1.8e-95 319.9 0.0 2.2e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) NusG_add PF18298.1 RJW59558.1 - 0.2 11.9 0.6 9.9 6.4 0.2 2.4 2 0 0 2 2 2 0 NusG additional domain DSS1_SEM1 PF05160.13 RJW59558.1 - 4.1 7.5 7.1 84 3.3 7.1 2.5 1 1 0 1 1 1 0 DSS1/SEM1 family TPR_12 PF13424.6 RJW59559.1 - 8.1e-51 170.2 19.2 8.1e-19 67.7 1.8 5.7 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 RJW59559.1 - 8.9e-44 146.2 10.0 5.4e-13 48.4 0.2 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 RJW59559.1 - 3e-18 64.4 7.1 0.00054 19.8 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 RJW59559.1 - 1.1e-15 56.7 14.3 0.00029 20.5 0.1 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW59559.1 - 3.3e-12 45.5 14.5 0.0021 18.1 0.5 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW59559.1 - 2.7e-10 40.2 0.4 2.7e-10 40.2 0.4 2.1 3 0 0 3 3 3 1 MalT-like TPR region TPR_8 PF13181.6 RJW59559.1 - 5e-08 32.5 9.0 0.18 12.1 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW59559.1 - 2.8e-07 31.1 15.0 0.00091 19.8 7.6 4.9 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 RJW59559.1 - 7.9e-07 29.1 11.2 0.096 13.4 0.9 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW59559.1 - 1.4e-06 28.6 15.5 0.046 14.5 0.8 6.0 3 1 3 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 RJW59559.1 - 0.00038 20.6 9.0 4.3 7.9 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW59559.1 - 0.0053 17.2 18.4 0.09 13.3 3.2 4.7 3 1 3 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW59559.1 - 0.048 13.9 3.7 0.99 9.7 0.2 3.4 3 1 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Rhabdo_M1 PF03342.13 RJW59559.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) TPR_6 PF13174.6 RJW59559.1 - 0.13 13.0 0.4 0.13 13.0 0.4 4.3 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 RJW59559.1 - 0.13 12.3 0.6 6.5 6.9 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.7 RJW59559.1 - 0.22 11.7 3.7 1.2 9.4 0.0 3.4 4 0 0 4 4 3 0 Tetratrico peptide repeat TPR_11 PF13414.6 RJW59559.1 - 0.28 10.9 5.7 0.55 10.0 0.2 3.5 4 0 0 4 4 4 0 TPR repeat SHNi-TPR PF10516.9 RJW59559.1 - 0.7 9.4 2.5 10 5.7 0.0 3.6 4 0 0 4 4 4 0 SHNi-TPR NUDE_C PF04880.13 RJW59559.1 - 0.71 10.3 8.5 0.25 11.8 4.3 2.5 2 1 1 3 3 3 0 NUDE protein, C-terminal conserved region Myosin_head PF00063.21 RJW59562.1 - 1.2e-284 945.9 1.9 1.2e-284 945.9 1.9 2.6 3 0 0 3 3 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 RJW59562.1 - 1.5e-171 572.8 290.1 1.8e-171 572.5 290.1 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 RJW59562.1 - 1.1e-11 44.4 6.8 3.1e-11 42.9 6.8 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ATG16 PF08614.11 RJW59562.1 - 3.9e-06 27.2 284.8 0.06 13.6 19.2 10.8 1 1 9 10 10 10 5 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 RJW59562.1 - 8.6e-05 22.3 46.6 8.6e-05 22.3 46.6 11.1 2 1 6 10 10 9 3 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 RJW59562.1 - 9.5e-05 22.1 246.4 0.00014 21.6 54.5 10.3 1 1 4 7 7 5 3 Intermediate filament protein Sec2p PF06428.11 RJW59562.1 - 0.00024 21.0 25.9 0.00034 20.5 4.8 16.0 4 4 11 15 15 12 2 GDP/GTP exchange factor Sec2p BRE1 PF08647.11 RJW59562.1 - 0.0011 19.0 37.3 0.0014 18.6 4.5 14.7 1 1 15 16 16 11 4 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 RJW59562.1 - 0.0012 18.8 161.4 0.097 12.7 0.9 14.4 2 2 12 15 15 15 9 Protein of unknown function (DUF1664) SlyX PF04102.12 RJW59562.1 - 0.0015 19.1 8.9 0.0015 19.1 8.9 19.9 7 4 11 20 20 16 5 SlyX Tropomyosin_1 PF12718.7 RJW59562.1 - 0.0017 18.5 28.3 0.0017 18.5 28.3 11.8 1 1 7 10 10 8 3 Tropomyosin like TMF_TATA_bd PF12325.8 RJW59562.1 - 0.0019 18.4 5.8 0.0019 18.4 5.8 16.7 2 1 17 19 19 13 1 TATA element modulatory factor 1 TATA binding Tropomyosin PF00261.20 RJW59562.1 - 0.0028 17.0 41.5 0.0028 17.0 41.5 7.2 1 1 5 6 6 3 1 Tropomyosin IQ PF00612.27 RJW59562.1 - 0.0064 16.2 4.0 0.037 13.8 0.4 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.6 RJW59562.1 - 0.11 12.8 0.0 0.11 12.8 0.0 5.9 6 2 1 7 7 7 0 AAA domain NACHT PF05729.12 RJW59563.1 - 0.00031 20.7 0.0 0.00092 19.2 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 RJW59563.1 - 0.0019 18.6 0.0 0.0075 16.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RJW59563.1 - 0.0031 17.8 0.0 0.0094 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RJW59563.1 - 0.027 14.8 0.1 0.24 11.8 0.0 2.6 3 0 0 3 3 3 0 RNA helicase TAL_FSA PF00923.19 RJW59564.1 - 7.7e-74 248.6 0.0 2.8e-73 246.8 0.0 1.7 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase OCRE PF17780.1 RJW59565.1 - 0.15 12.1 1.3 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 OCRE domain Tetraspanin PF00335.20 RJW59570.1 - 2.5e-14 53.6 3.9 3.2e-14 53.2 3.9 1.2 1 0 0 1 1 1 1 Tetraspanin family Phage_holin_5_2 PF16079.5 RJW59570.1 - 5.3e-05 23.5 0.5 0.14 12.5 0.3 2.3 2 0 0 2 2 2 2 Phage holin family Hol44, in holin superfamily V RVT_1 PF00078.27 RJW59571.1 - 4.4e-46 157.2 0.3 1.1e-45 155.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT PF02985.22 RJW59571.1 - 4.8e-23 79.3 24.3 0.011 16.0 0.1 10.8 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.6 RJW59571.1 - 8.3e-20 71.0 11.8 0.00015 22.1 0.0 7.3 4 2 1 5 5 5 5 HEAT repeats Exo_endo_phos_2 PF14529.6 RJW59571.1 - 6.4e-12 45.4 0.1 7.8e-11 41.9 0.0 2.8 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase HEAT_EZ PF13513.6 RJW59571.1 - 0.001 19.5 11.9 23 5.6 0.1 6.8 5 2 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 RJW59571.1 - 0.0048 17.0 4.7 0.32 11.0 0.1 4.2 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RJW59571.1 - 0.14 10.7 2.1 5.6 5.4 0.2 3.2 3 1 0 3 3 3 0 Adaptin N terminal region Y_phosphatase PF00102.27 RJW59572.1 - 7.5e-61 205.7 0.0 1.4e-60 204.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 RJW59572.1 - 6e-24 84.2 29.7 0.0018 18.6 0.2 8.9 8 0 0 8 8 8 7 Fibronectin type III domain DSPc PF00782.20 RJW59572.1 - 0.00017 21.4 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PA_decarbox PF05870.11 RJW59572.1 - 0.082 12.5 0.3 2.3 7.9 0.1 3.1 3 0 0 3 3 3 0 Phenolic acid decarboxylase (PAD) Ras PF00071.22 RJW59573.1 - 1.3e-24 86.7 0.0 1.5e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.21 RJW59573.1 - 1.2e-05 24.8 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RJW59573.1 - 3.9e-05 23.8 0.0 6.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TPP_enzyme_M PF00205.22 RJW59573.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain CENP-M PF11111.8 RJW59573.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) 7tm_1 PF00001.21 RJW59575.1 - 1.4e-35 123.0 6.4 1.4e-35 123.0 6.4 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW59575.1 - 0.004 16.8 4.8 0.004 16.8 4.8 2.9 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF5326 PF17260.2 RJW59575.1 - 0.36 11.0 7.5 6.5 7.0 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5326) RVT_1 PF00078.27 RJW59578.1 - 2.2e-05 24.1 0.0 4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 RJW59579.1 - 3e-05 23.6 0.0 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Homeobox_KN PF05920.11 RJW59580.1 - 1.2e-15 57.1 0.2 3.6e-15 55.6 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RJW59580.1 - 5.1e-07 29.4 0.8 1.5e-06 27.9 0.8 1.9 1 0 0 1 1 1 1 Homeodomain NCU-G1 PF15065.6 RJW59581.1 - 2.2e-23 82.8 0.0 3.6e-16 59.1 0.0 2.0 2 0 0 2 2 2 2 Lysosomal transcription factor, NCU-G1 Gram_pos_anchor PF00746.21 RJW59581.1 - 0.0041 17.0 0.2 0.0077 16.1 0.2 1.4 1 0 0 1 1 1 1 LPXTG cell wall anchor motif DUF2642 PF10842.8 RJW59582.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) ER_lumen_recept PF00810.18 RJW59584.1 - 8.1e-41 140.3 14.3 1.4e-40 139.5 14.3 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor NCU-G1 PF15065.6 RJW59585.1 - 0.023 13.7 0.1 0.029 13.4 0.1 1.1 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 DUF807 PF05660.11 RJW59585.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) Prominin PF05478.11 RJW59587.1 - 1.3e-14 53.2 25.2 2.1e-13 49.2 25.2 2.3 1 1 0 1 1 1 1 Prominin QIL1 PF15884.5 RJW59587.1 - 0.00021 21.8 0.1 0.002 18.7 0.0 2.7 2 0 0 2 2 1 1 MICOS complex subunit MIC13, QIL1 PLU-1 PF08429.11 RJW59587.1 - 0.0091 15.2 16.3 0.083 12.0 3.1 3.0 2 1 1 3 3 3 2 PLU-1-like protein Ins_allergen_rp PF06757.13 RJW59587.1 - 0.016 15.1 4.9 0.15 12.0 1.5 2.6 2 1 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Cytochrom_B562 PF07361.11 RJW59587.1 - 0.03 15.0 6.5 0.62 10.7 0.1 3.9 3 1 0 3 3 3 0 Cytochrome b562 DUF2207 PF09972.9 RJW59587.1 - 0.032 13.0 9.9 0.04 12.7 0.1 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF1218 PF06749.12 RJW59587.1 - 0.04 14.4 0.8 0.04 14.4 0.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Tweety PF04906.13 RJW59587.1 - 0.068 11.8 22.6 0.095 11.4 0.8 4.6 2 2 1 4 4 4 0 Tweety Fib_alpha PF08702.10 RJW59587.1 - 0.08 13.1 16.8 0.98 9.6 0.3 4.3 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 RJW59587.1 - 0.089 13.2 18.9 0.36 11.2 1.3 4.7 3 1 1 4 4 4 0 Syntaxin-like protein Sec34 PF04136.15 RJW59587.1 - 0.13 12.1 12.2 0.081 12.8 0.4 3.6 3 1 0 3 3 3 0 Sec34-like family Macoilin PF09726.9 RJW59587.1 - 0.17 10.4 3.6 0.38 9.2 0.0 2.2 2 0 0 2 2 2 0 Macoilin family Spore_III_AB PF09548.10 RJW59587.1 - 0.23 11.6 5.9 0.58 10.2 0.1 3.2 2 2 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) ALIX_LYPXL_bnd PF13949.6 RJW59587.1 - 0.28 10.4 15.7 0.012 14.9 4.7 2.3 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Cas_DxTHG PF09455.10 RJW59587.1 - 0.38 10.3 5.6 2.1 7.9 1.1 2.5 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family COG2 PF06148.11 RJW59587.1 - 0.51 10.4 13.8 0.22 11.6 1.2 3.8 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 VWA_2 PF13519.6 RJW59587.1 - 0.77 10.4 7.8 16 6.2 0.0 4.8 3 1 2 5 5 5 0 von Willebrand factor type A domain DUF456 PF04306.13 RJW59587.1 - 1.3 9.3 15.0 3.1 8.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Med9 PF07544.13 RJW59587.1 - 1.6 8.9 8.6 0.9 9.7 0.2 3.6 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SKA2 PF16740.5 RJW59587.1 - 2.9 7.7 20.7 0.3 10.9 2.5 4.6 3 2 1 4 4 4 0 Spindle and kinetochore-associated protein 2 DUF4298 PF14131.6 RJW59587.1 - 4.2 7.4 10.2 8.2 6.5 0.3 4.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4298) ApoC-I PF04691.12 RJW59587.1 - 6.5 6.8 6.1 10 6.2 0.1 3.4 4 0 0 4 4 3 0 Apolipoprotein C-I (ApoC-1) DUF1664 PF07889.12 RJW59587.1 - 6.8 6.7 17.2 7.7 6.6 0.3 4.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) vWA-TerF-like PF10138.9 RJW59588.1 - 0.19 11.8 0.0 1.5 8.9 0.0 2.3 3 0 0 3 3 3 0 vWA found in TerF C terminus HbrB PF08539.11 RJW59589.1 - 0.003 17.6 0.3 0.0052 16.8 0.2 1.7 1 1 0 1 1 1 1 HbrB-like ubiquitin PF00240.23 RJW59590.1 - 0.0055 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family 7tm_1 PF00001.21 RJW59592.1 - 5.5e-35 121.0 8.1 5.5e-35 121.0 8.1 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW59592.1 - 0.00062 19.5 6.2 0.00062 19.5 6.2 3.2 3 1 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RJW59592.1 - 0.00081 18.8 9.4 0.17 11.2 5.5 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx TMIE PF16038.5 RJW59592.1 - 2.2 8.2 4.1 0.93 9.4 1.1 1.9 2 0 0 2 2 2 0 TMIE protein V-ATPase_H_N PF03224.14 RJW59594.1 - 1.7e-54 185.3 2.2 8.9e-54 182.9 0.5 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 RJW59594.1 - 3.2e-45 153.0 0.3 6.7e-45 152.0 0.2 1.6 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 RJW59594.1 - 0.0011 19.3 0.0 0.0062 16.9 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 RJW59594.1 - 0.0022 18.1 0.0 0.011 16.0 0.0 2.2 1 0 0 1 1 1 1 HEAT repeat Arm PF00514.23 RJW59594.1 - 0.011 15.8 0.1 15 5.8 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RJW59594.1 - 0.025 14.1 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Armadillo-like Cyt-b5 PF00173.28 RJW59594.1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Adaptin_N PF01602.20 RJW59594.1 - 0.093 11.3 1.3 2.1 6.8 0.0 2.6 2 2 1 3 3 3 0 Adaptin N terminal region CsiV PF10972.8 RJW59595.1 - 0.06 13.1 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV PNTB PF02233.16 RJW59597.1 - 1.8e-175 584.3 17.3 1.8e-175 584.3 17.3 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 RJW59597.1 - 1.1e-71 240.5 0.5 2.5e-71 239.4 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 RJW59597.1 - 9.5e-42 142.5 0.0 2.3e-41 141.3 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 RJW59597.1 - 5.9e-32 110.0 1.6 5.9e-32 110.0 1.6 4.3 4 2 1 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch ADH_zinc_N PF00107.26 RJW59597.1 - 0.0089 16.0 0.1 0.094 12.7 0.2 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RJW59597.1 - 0.012 15.0 0.9 2.1 7.6 0.1 2.9 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 RJW59597.1 - 0.014 14.6 0.2 0.024 13.8 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RJW59597.1 - 0.031 14.9 0.4 0.45 11.1 1.4 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 RJW59597.1 - 0.15 11.8 1.1 24 4.6 0.0 3.4 3 1 1 4 4 4 0 Thiamine pyrophosphate enzyme, central domain NAD_binding_8 PF13450.6 RJW59597.1 - 1.8 8.9 6.4 0.84 9.9 0.7 3.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain CbtB PF09489.10 RJW59597.1 - 6.1 7.0 5.9 4.5 7.5 0.1 3.6 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Sec16 PF12932.7 RJW59599.1 - 0.0038 17.8 0.0 0.0077 16.8 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region ox_reductase_C PF08635.10 RJW59601.1 - 0.012 15.3 0.1 0.024 14.3 0.1 1.5 1 1 0 1 1 1 0 Putative oxidoreductase C terminal domain Tetraspanin PF00335.20 RJW59602.1 - 1.8e-11 44.2 3.1 2.3e-11 43.9 3.1 1.1 1 0 0 1 1 1 1 Tetraspanin family LHC PF00556.20 RJW59602.1 - 5 7.4 6.1 0.43 10.8 0.8 2.0 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit SCAMP PF04144.13 RJW59604.1 - 5.2e-55 186.4 4.7 6.5e-55 186.1 4.7 1.1 1 0 0 1 1 1 1 SCAMP family DAZAP2 PF11029.8 RJW59604.1 - 0.013 16.4 0.1 0.026 15.5 0.1 1.6 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) RDD PF06271.12 RJW59604.1 - 4.7 7.4 8.7 2.4 8.3 0.1 2.8 2 1 0 2 2 2 0 RDD family Glyco_hydro_35 PF01301.19 RJW59606.1 - 2.6e-107 359.1 0.0 3.5e-107 358.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 RJW59606.1 - 3.2e-11 43.2 0.3 8.1e-10 38.6 0.3 2.1 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 RJW59606.1 - 1.2e-05 25.9 0.1 0.56 10.8 0.0 3.6 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain KH_1 PF00013.29 RJW59607.1 - 2.4e-23 81.7 2.0 1.5e-12 47.1 0.6 2.5 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 RJW59607.1 - 5.3e-13 48.6 1.1 1.1e-06 28.4 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 RJW59607.1 - 0.0001 22.1 0.3 0.08 12.8 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 RJW59607.1 - 0.0009 19.3 0.8 0.66 10.1 0.0 2.5 2 0 0 2 2 2 2 NusA-like KH domain Histone PF00125.24 RJW59608.1 - 1e-41 142.4 0.1 1.3e-41 142.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RJW59608.1 - 9.2e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RJW59608.1 - 0.0024 18.2 0.0 0.0041 17.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 RJW59608.1 - 0.032 14.5 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DEAD PF00270.29 RJW59610.1 - 6e-17 62.0 0.1 1.6e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW59610.1 - 1.1e-12 48.3 0.0 4.4e-08 33.5 0.0 2.4 1 1 1 2 2 2 2 Helicase conserved C-terminal domain Cystatin PF00031.21 RJW59610.1 - 0.019 15.2 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Cystatin domain SQAPI PF16845.5 RJW59610.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor Aldedh PF00171.22 RJW59611.1 - 1.2e-179 597.7 0.0 1.3e-179 597.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1676 PF07898.13 RJW59612.1 - 0.097 12.7 0.9 0.092 12.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Ank_2 PF12796.7 RJW59615.1 - 1.6e-47 160.0 8.2 6.9e-13 49.0 0.0 5.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW59615.1 - 6.1e-39 131.6 6.2 4.4e-08 33.3 0.0 8.9 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW59615.1 - 3.6e-34 116.7 5.4 1.3e-10 41.6 0.0 8.2 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW59615.1 - 2.8e-32 107.1 4.5 0.00012 22.3 0.0 10.8 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 RJW59615.1 - 1.6e-28 97.9 9.0 0.00017 21.9 0.0 9.5 9 1 1 10 10 10 6 Ankyrin repeat Death PF00531.22 RJW59615.1 - 2.2e-06 27.7 0.1 6.7e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 Death domain Keratin_2_head PF16208.5 RJW59616.1 - 0.033 14.3 4.8 0.048 13.8 4.8 1.1 1 0 0 1 1 1 0 Keratin type II head NAD_binding_11 PF14833.6 RJW59618.1 - 0.05 13.8 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Branch PF02485.21 RJW59620.1 - 5e-31 108.1 0.0 6.7e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme BORCS8 PF10167.9 RJW59622.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 TF_Otx PF03529.13 RJW59622.1 - 0.06 13.7 3.0 0.098 13.1 2.0 1.9 2 1 0 2 2 2 0 Otx1 transcription factor Histone PF00125.24 RJW59623.1 - 9.8e-54 181.2 2.2 1.1e-53 181.1 2.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RJW59623.1 - 4.7e-05 23.5 0.3 8.6e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 RJW59623.1 - 0.00014 22.4 0.9 0.00015 22.3 0.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 RJW59623.1 - 0.00031 21.1 0.0 0.00047 20.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 RJW59623.1 - 0.0089 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RJW59623.1 - 0.076 13.1 0.1 0.15 12.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Adeno_E3_CR2 PF02439.15 RJW59624.1 - 4.8 7.0 6.4 0.34 10.7 1.6 1.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 TTL PF03133.15 RJW59625.1 - 3.6e-63 213.4 0.0 1.3e-45 155.8 0.0 2.4 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family RVT_1 PF00078.27 RJW59625.1 - 4.4e-39 134.3 0.0 9e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATPgrasp_YheCD PF14398.6 RJW59625.1 - 8.7e-06 25.2 0.1 0.00037 19.8 0.0 2.8 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RJW59625.1 - 0.00011 21.6 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 RJW59625.1 - 0.0016 18.5 0.0 0.63 10.1 0.0 3.5 4 0 0 4 4 4 1 ATP-grasp domain DUF2656 PF10847.8 RJW59625.1 - 0.039 14.1 0.0 0.74 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) Bac_surface_Ag PF01103.23 RJW59626.1 - 4.1e-23 82.4 0.1 5.9e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 Surface antigen zf-C2H2 PF00096.26 RJW59626.1 - 0.00034 20.9 13.0 0.0021 18.4 1.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_ribbon_SprT PF17283.2 RJW59626.1 - 0.011 15.6 4.5 0.027 14.4 4.2 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_4 PF13894.6 RJW59626.1 - 0.018 15.8 1.1 0.018 15.8 1.1 3.3 3 0 0 3 3 2 0 C2H2-type zinc finger PyrI_C PF02748.15 RJW59626.1 - 0.092 12.7 3.1 0.25 11.3 1.2 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 RJW59626.1 - 0.16 12.3 2.1 0.36 11.2 2.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 RJW59626.1 - 0.27 11.3 1.9 0.59 10.2 1.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 RJW59626.1 - 1.5 8.6 3.7 2.6 7.9 0.3 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 RJW59626.1 - 2 8.6 5.2 15 5.8 0.3 2.5 1 1 2 3 3 3 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 RJW59626.1 - 2 8.4 4.0 22 5.1 4.0 2.4 1 1 0 1 1 1 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 RJW59626.1 - 2.9 8.0 4.9 35 4.5 3.6 2.8 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger UPF0547 PF10571.9 RJW59626.1 - 5.8 7.1 5.3 1 9.5 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PH PF00169.29 RJW59628.1 - 3e-11 43.7 0.4 8.3e-10 39.1 0.1 2.6 2 1 0 2 2 2 1 PH domain MORN PF02493.20 RJW59629.1 - 7.2e-39 129.4 47.2 5.2e-07 29.2 0.8 7.6 8 0 0 8 8 8 7 MORN repeat MORN_2 PF07661.13 RJW59629.1 - 0.49 10.8 0.3 0.49 10.8 0.3 5.5 5 2 1 6 6 6 0 MORN repeat variant RVT_1 PF00078.27 RJW59631.1 - 1.5e-44 152.2 0.0 2.4e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ADAM_CR PF08516.12 RJW59631.1 - 9e-16 58.3 5.4 9e-16 58.3 5.4 5.4 5 0 0 5 5 5 1 ADAM cysteine-rich Disintegrin PF00200.23 RJW59631.1 - 7.5e-15 55.5 15.2 7.5e-15 55.5 15.2 7.7 9 1 0 9 9 9 1 Disintegrin Pep_M12B_propep PF01562.19 RJW59631.1 - 2.4e-11 44.0 0.0 2.4e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin PF01421.19 RJW59631.1 - 1.1e-10 41.8 0.0 1.5e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease MULE PF10551.9 RJW59633.1 - 0.0069 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain RasGEF PF00617.19 RJW59634.1 - 1e-54 185.4 1.9 2e-54 184.5 1.9 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RJW59634.1 - 0.00033 20.9 0.2 0.0012 19.1 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif SurA_N PF09312.11 RJW59634.1 - 1.7 8.7 4.3 5.2 7.2 0.0 2.8 3 0 0 3 3 3 0 SurA N-terminal domain Porin_3 PF01459.22 RJW59635.1 - 7.3e-41 140.4 0.6 8.8e-41 140.1 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin 2-oxoacid_dh PF00198.23 RJW59636.1 - 5e-75 251.9 0.0 6.1e-75 251.6 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RJW59636.1 - 3.6e-19 68.4 0.3 7.4e-19 67.4 0.0 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 RJW59636.1 - 9.5e-10 38.7 0.2 3.6e-09 36.8 0.1 2.2 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 RJW59636.1 - 4.5e-05 23.2 0.0 0.00021 21.0 0.0 2.2 1 1 0 1 1 1 1 Biotin-lipoyl like RasGEF_N PF00618.20 RJW59637.1 - 1.5e-13 50.8 0.1 4.5e-13 49.3 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif PH PF00169.29 RJW59637.1 - 0.078 13.5 0.0 1.3 9.6 0.0 2.5 2 0 0 2 2 2 0 PH domain rve PF00665.26 RJW59641.1 - 1e-05 25.7 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 RJW59641.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease ABC_tran PF00005.27 RJW59642.1 - 2.2e-52 177.2 0.0 7.6e-25 88.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RJW59642.1 - 8e-20 71.8 0.0 0.00025 21.0 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RJW59642.1 - 1e-11 44.6 7.9 1e-11 44.6 7.9 2.5 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_23 PF13476.6 RJW59642.1 - 1.1e-08 35.9 1.9 0.0016 19.0 0.6 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RJW59642.1 - 2.7e-07 30.2 0.7 0.017 14.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RJW59642.1 - 5e-07 29.8 0.1 0.0086 16.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RJW59642.1 - 1.1e-05 26.0 0.0 0.0073 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 RJW59642.1 - 3.3e-05 23.7 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RJW59642.1 - 3.5e-05 23.4 0.0 0.82 9.1 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 RJW59642.1 - 0.00011 22.1 0.1 0.084 12.6 0.0 2.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 RJW59642.1 - 0.0017 18.6 0.4 0.3 11.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 RJW59642.1 - 0.0036 16.9 0.3 3.2 7.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 RJW59642.1 - 0.0043 16.8 0.0 0.088 12.5 0.1 2.6 3 0 0 3 3 3 1 AAA ATPase domain ATP_bind_1 PF03029.17 RJW59642.1 - 0.0078 16.0 0.2 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 RJW59642.1 - 0.019 15.0 0.3 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RJW59642.1 - 0.038 13.5 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 RJW59642.1 - 0.066 13.4 0.1 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RJW59642.1 - 0.081 12.8 0.2 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 RJW59642.1 - 0.085 12.6 0.0 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RJW59642.1 - 0.12 12.9 0.1 6.9 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 RJW59642.1 - 0.14 11.8 0.2 9 5.9 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 RJW59642.1 - 0.14 12.4 1.1 3.9 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 RJW59642.1 - 0.2 10.2 0.6 0.99 8.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 RJW59642.1 - 0.24 11.0 0.8 3.2 7.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Wzy_C PF04932.15 RJW59642.1 - 2.7 7.6 9.2 9.5 5.8 0.5 3.4 3 0 0 3 3 3 0 O-Antigen ligase Glyco_transf_64 PF09258.10 RJW59644.1 - 5.8e-82 274.7 0.2 1.3e-81 273.5 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 RJW59644.1 - 0.00036 19.8 0.0 0.00062 19.1 0.0 1.5 1 0 0 1 1 1 1 Exostosin family NUSAP PF16006.5 RJW59645.1 - 0.006 16.4 11.2 0.013 15.3 11.2 1.5 1 1 0 1 1 1 1 Nucleolar and spindle-associated protein CDPS PF16715.5 RJW59645.1 - 0.032 13.9 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Cyclodipeptide synthase DUF2572 PF10833.8 RJW59646.1 - 1 9.0 2.8 1.3 8.7 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) ABC2_membrane_3 PF12698.7 RJW59646.1 - 1.2 8.2 7.6 1.3 8.0 7.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein CDO_I PF05995.12 RJW59647.1 - 2.5e-51 173.4 0.0 3.2e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 RJW59647.1 - 6.8e-05 22.4 0.0 0.00016 21.2 0.0 1.6 2 1 0 2 2 2 1 PCO_ADO rve PF00665.26 RJW59648.1 - 0.0036 17.5 0.0 0.0076 16.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain PH PF00169.29 RJW59649.1 - 8.7e-07 29.4 0.0 2e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 PH domain DUF4200 PF13863.6 RJW59649.1 - 0.00028 21.3 1.2 0.00035 21.0 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) CortBP2 PF09727.9 RJW59649.1 - 0.00054 19.9 0.8 0.00069 19.6 0.8 1.1 1 0 0 1 1 1 1 Cortactin-binding protein-2 EzrA PF06160.12 RJW59649.1 - 0.0016 16.7 1.0 0.0019 16.4 1.0 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA PH_13 PF16652.5 RJW59649.1 - 0.0081 16.0 0.4 0.012 15.4 0.1 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain Methyltransf_14 PF08484.11 RJW59649.1 - 0.087 12.6 0.4 0.12 12.2 0.4 1.2 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Suppressor_APC PF11414.8 RJW59649.1 - 0.14 12.2 4.7 0.22 11.6 4.7 1.3 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein UPF0203 PF05254.12 RJW59649.1 - 0.58 10.4 3.7 1.6 9.0 0.1 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) Abhydrolase_1 PF00561.20 RJW59650.1 - 0.056 13.1 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold PH PF00169.29 RJW59652.1 - 5.5e-07 30.1 0.7 2.2e-06 28.1 0.7 1.9 1 1 0 1 1 1 1 PH domain UPAR_LY6_2 PF16975.5 RJW59653.1 - 0.013 15.7 11.4 0.02 15.1 11.4 1.3 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Tetraspanin PF00335.20 RJW59656.1 - 1.4e-20 74.1 14.3 1.7e-20 73.7 14.3 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF948 PF06103.11 RJW59656.1 - 0.13 12.6 2.5 3.3 8.0 0.9 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2981 PF11200.8 RJW59656.1 - 0.15 11.8 2.0 0.26 11.0 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) P53_TAD PF08563.11 RJW59656.1 - 0.16 11.5 0.1 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 P53 transactivation motif SUR7 PF06687.12 RJW59656.1 - 2.5 7.7 19.6 0.57 9.8 8.6 2.8 2 1 0 2 2 2 0 SUR7/PalI family LRR_6 PF13516.6 RJW59658.1 - 9.8e-05 22.1 0.3 0.00042 20.1 0.0 2.1 2 0 0 2 2 2 1 Leucine Rich repeat Ribosomal_S18 PF01084.20 RJW59658.1 - 0.084 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S18 EutC PF05985.11 RJW59659.1 - 0.17 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) Asp PF00026.23 RJW59660.1 - 8.3e-31 107.6 0.1 1e-30 107.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW59660.1 - 0.00035 20.4 0.2 0.0012 18.6 0.1 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal fn3 PF00041.21 RJW59661.1 - 1.8e-26 92.3 4.3 4.1e-09 36.7 0.0 4.2 3 1 0 3 3 3 3 Fibronectin type III domain I-set PF07679.16 RJW59661.1 - 1.3e-16 60.4 0.5 4.5e-08 33.0 0.0 6.2 7 1 0 7 7 7 2 Immunoglobulin I-set domain V-set PF07686.17 RJW59661.1 - 5.5e-14 52.3 1.7 1.3e-06 28.5 0.0 5.3 6 0 0 6 6 6 2 Immunoglobulin V-set domain Ig_3 PF13927.6 RJW59661.1 - 7.6e-14 52.1 11.8 2.8e-06 27.8 0.0 7.0 6 2 0 6 6 6 2 Immunoglobulin domain ig PF00047.25 RJW59661.1 - 9e-11 41.8 3.2 0.0033 17.6 0.0 5.4 6 0 0 6 6 6 2 Immunoglobulin domain Ig_2 PF13895.6 RJW59661.1 - 1.7e-10 41.1 2.7 0.0043 17.4 0.1 6.3 4 3 0 4 4 4 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RJW59661.1 - 3.1e-05 24.5 3.2 1.7 9.3 0.1 4.6 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 RJW59661.1 - 4.8e-05 23.3 0.3 0.039 14.0 0.1 2.9 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RJW59661.1 - 0.0076 16.3 0.0 1.8 8.7 0.0 3.3 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RJW59661.1 - 0.027 14.0 0.0 3.5 7.3 0.0 3.2 3 0 0 3 3 3 0 Immunoglobulin domain GPI-anchored PF10342.9 RJW59661.1 - 0.097 13.4 1.0 1 10.1 0.1 3.1 4 0 0 4 4 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Linker_histone PF00538.19 RJW59662.1 - 2.1e-17 63.2 0.0 3.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family Ribosomal_L23 PF00276.20 RJW59662.1 - 0.078 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L23 Kelch_4 PF13418.6 RJW59663.1 - 3.5e-07 30.1 3.0 0.21 11.6 0.0 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RJW59663.1 - 0.04 14.2 1.8 15 6.0 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.6 RJW59663.1 - 3.4 8.1 11.3 16 5.9 0.1 4.6 4 1 0 4 4 4 0 Galactose oxidase, central domain EF-hand_1 PF00036.32 RJW59664.1 - 1.6e-30 102.3 4.6 6e-07 28.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW59664.1 - 1.1e-29 102.7 3.3 1.2e-15 57.7 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW59664.1 - 4.4e-25 86.0 3.4 9.1e-06 24.9 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RJW59664.1 - 1.7e-24 83.6 1.1 1.6e-06 27.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RJW59664.1 - 9.2e-22 76.7 6.6 1.9e-08 34.0 0.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW59664.1 - 1.6e-09 38.1 0.4 1.2e-05 25.6 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 RJW59664.1 - 3.3e-08 33.6 2.6 0.00083 19.5 0.2 3.9 2 1 2 4 4 4 3 Dockerin type I domain EF-hand_9 PF14658.6 RJW59664.1 - 6.1e-08 32.9 0.1 0.0029 17.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RJW59664.1 - 4e-05 23.5 2.1 0.011 15.7 0.2 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 RJW59664.1 - 0.015 15.2 0.2 4.4 7.2 0.0 2.7 1 1 2 3 3 3 0 Tellurite resistance protein TerB Caleosin PF05042.13 RJW59664.1 - 0.023 14.6 0.1 0.44 10.5 0.0 2.4 2 1 0 2 2 2 0 Caleosin related protein DUF1296 PF06972.11 RJW59664.1 - 0.058 13.5 0.5 0.69 10.1 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1296) RPT PF13446.6 RJW59664.1 - 0.11 12.5 0.2 0.39 10.7 0.1 2.0 2 1 0 2 2 2 0 A repeated domain in UCH-protein PITH PF06201.13 RJW59666.1 - 1.1e-27 97.1 0.0 1.7e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 RJW59666.1 - 2.2e-22 79.0 0.0 3.7e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RJW59666.1 - 3.1e-08 34.0 0.0 9.8e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RJW59666.1 - 2e-06 28.1 0.1 0.002 18.4 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 RJW59666.1 - 2.1e-05 24.1 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 RJW59666.1 - 0.00051 19.8 0.0 0.0008 19.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 RJW59666.1 - 0.00098 19.0 0.1 0.0058 16.5 0.0 2.3 2 1 0 2 2 2 1 AhpC/TSA family HyaE PF07449.11 RJW59666.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Snf7 PF03357.21 RJW59667.1 - 4.2e-42 143.7 11.8 4.7e-42 143.5 11.8 1.0 1 0 0 1 1 1 1 Snf7 DUF1319 PF07028.11 RJW59667.1 - 0.0044 17.2 3.3 0.0044 17.2 3.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1319) E2F_CC-MB PF16421.5 RJW59667.1 - 0.043 14.2 3.3 0.078 13.3 3.3 1.5 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain IFP_35_N PF07334.13 RJW59667.1 - 0.059 13.4 0.5 0.059 13.4 0.5 2.2 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus BBS1 PF14779.6 RJW59667.1 - 0.09 12.2 2.1 0.12 11.8 2.1 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 MIS13 PF08202.11 RJW59667.1 - 0.1 11.8 8.5 0.13 11.5 8.5 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Spc7 PF08317.11 RJW59667.1 - 0.11 11.4 9.9 0.15 10.9 9.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Vps53_N PF04100.12 RJW59667.1 - 0.16 10.9 7.9 0.21 10.5 7.9 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal CorA PF01544.18 RJW59667.1 - 0.29 10.4 4.9 0.99 8.7 3.3 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein FlaC_arch PF05377.11 RJW59667.1 - 0.39 11.2 6.6 0.35 11.3 0.7 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.11 RJW59667.1 - 3.1 7.2 5.8 3.7 7.0 0.7 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein ABC_tran_CTD PF16326.5 RJW59667.1 - 4.1 7.7 7.0 2.2 8.6 1.4 2.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain PDZ PF00595.24 RJW59670.1 - 2.2e-66 220.2 7.1 9.7e-14 51.5 0.1 6.4 6 0 0 6 6 6 5 PDZ domain PDZ_6 PF17820.1 RJW59670.1 - 2.1e-41 139.5 18.4 6.6e-10 38.7 0.1 6.6 6 0 0 6 6 6 5 PDZ domain PDZ_2 PF13180.6 RJW59670.1 - 2.6e-19 69.3 0.7 0.014 15.7 0.0 6.4 6 0 0 6 6 6 6 PDZ domain Guanylate_kin PF00625.21 RJW59670.1 - 6.8e-09 35.7 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase WW PF00397.26 RJW59670.1 - 0.00085 19.4 0.4 0.0016 18.5 0.4 1.5 1 0 0 1 1 1 1 WW domain Tricorn_PDZ PF14685.6 RJW59670.1 - 0.021 14.8 7.4 7.9 6.5 0.2 4.9 6 0 0 6 6 6 0 Tricorn protease PDZ domain PDZ_4 PF17816.1 RJW59670.1 - 0.046 14.1 0.1 95 3.4 0.0 4.4 5 0 0 5 5 5 0 PDZ domain FYRC PF05965.14 RJW59670.1 - 0.051 13.7 0.6 63 3.8 0.0 4.2 4 0 0 4 4 4 0 F/Y rich C-terminus His_binding PF02098.16 RJW59670.1 - 0.12 12.4 0.0 7.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Tick histamine binding protein D123 PF07065.14 RJW59671.1 - 1.8e-65 221.1 4.1 8e-65 219.0 4.1 1.8 1 1 0 1 1 1 1 D123 Xol-1_GHMP-like PF09109.10 RJW59671.1 - 0.052 13.4 0.3 0.077 12.9 0.3 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like R2K_2 PF18299.1 RJW59671.1 - 0.1 12.5 0.2 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 ABC_tran PF00005.27 RJW59672.1 - 7.9e-34 117.1 0.0 3.3e-16 60.0 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 RJW59672.1 - 1.9e-13 50.0 6.2 5.4e-13 48.5 6.2 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 RJW59672.1 - 2.3e-11 43.6 5.3 8.2e-05 22.1 1.1 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RJW59672.1 - 2.1e-10 40.9 4.8 0.092 12.5 1.0 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 RJW59672.1 - 1.3e-08 34.2 3.0 1.3e-08 34.2 3.0 3.0 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_22 PF13401.6 RJW59672.1 - 2.1e-07 31.3 0.1 6.8e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RJW59672.1 - 3e-06 27.7 0.0 0.03 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 RJW59672.1 - 3.2e-06 27.6 0.0 0.06 13.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 RJW59672.1 - 3.7e-06 26.9 0.0 0.099 12.5 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase Fer4_6 PF12837.7 RJW59672.1 - 1.2e-05 25.1 2.6 1.2e-05 25.1 2.6 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.6 RJW59672.1 - 1.5e-05 24.9 0.4 0.2 11.3 0.0 3.0 4 0 0 4 4 4 2 AAA ATPase domain NACHT PF05729.12 RJW59672.1 - 1.7e-05 24.8 0.3 0.0098 15.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 RJW59672.1 - 0.00012 21.7 0.1 0.6 9.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 RJW59672.1 - 0.00016 21.6 0.0 0.042 13.8 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain SRP54 PF00448.22 RJW59672.1 - 0.00022 20.9 0.9 0.091 12.4 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.7 RJW59672.1 - 0.00031 20.7 0.7 0.00031 20.7 0.7 2.7 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_23 PF13476.6 RJW59672.1 - 0.00039 21.0 3.7 0.012 16.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 RJW59672.1 - 0.00039 20.2 0.1 0.17 11.5 0.0 2.7 3 0 0 3 3 2 1 Thymidylate kinase Fer4_21 PF14697.6 RJW59672.1 - 0.00091 19.3 12.6 0.00091 19.3 12.6 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain TsaE PF02367.17 RJW59672.1 - 0.0011 18.9 0.0 0.067 13.2 0.0 2.6 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RJW59672.1 - 0.0012 19.1 0.0 0.52 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 RJW59672.1 - 0.0012 18.9 1.1 0.0012 18.9 1.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain RNA_helicase PF00910.22 RJW59672.1 - 0.0014 19.0 0.2 1.9 8.9 0.0 2.8 3 0 0 3 3 2 1 RNA helicase Fer4_7 PF12838.7 RJW59672.1 - 0.0015 19.1 1.2 0.0015 19.1 1.2 2.9 2 1 2 4 4 4 2 4Fe-4S dicluster domain AAA_18 PF13238.6 RJW59672.1 - 0.003 18.1 0.1 5.4 7.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 RJW59672.1 - 0.0035 17.1 0.9 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 RJW59672.1 - 0.0057 16.8 13.0 0.0057 16.8 13.0 1.9 2 0 0 2 2 1 1 4Fe-4S dicluster domain AAA_28 PF13521.6 RJW59672.1 - 0.0074 16.5 0.0 2.6 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RJW59672.1 - 0.0087 15.6 0.0 0.28 10.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 RJW59672.1 - 0.012 15.6 0.2 1.5 8.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RJW59672.1 - 0.02 14.6 0.1 2.2 8.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 RJW59672.1 - 0.02 14.9 0.2 5.2 7.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain VirE PF05272.11 RJW59672.1 - 0.02 14.6 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E MMR_HSR1 PF01926.23 RJW59672.1 - 0.029 14.5 1.2 6.2 6.9 0.0 2.8 2 2 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 RJW59672.1 - 0.038 13.2 0.6 2.8 7.0 0.1 3.0 3 1 0 3 3 3 0 NB-ARC domain Fer4_16 PF13484.6 RJW59672.1 - 0.056 14.4 2.1 0.056 14.4 2.1 3.1 2 1 0 3 3 2 0 4Fe-4S double cluster binding domain Roc PF08477.13 RJW59672.1 - 0.071 13.3 0.7 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 RJW59672.1 - 0.14 11.4 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.12 RJW59672.1 - 0.17 11.2 0.2 5.3 6.3 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin TniB PF05621.11 RJW59672.1 - 0.17 11.2 0.4 1.4 8.3 0.0 2.5 3 1 0 3 3 3 0 Bacterial TniB protein MukB PF04310.12 RJW59672.1 - 0.18 11.6 0.1 15 5.3 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal NTPase_1 PF03266.15 RJW59672.1 - 0.36 10.7 3.6 9.1 6.2 0.0 3.3 4 0 0 4 4 3 0 NTPase Fer4_8 PF13183.6 RJW59672.1 - 0.52 10.8 10.0 0.21 12.0 1.2 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 RJW59672.1 - 0.54 10.9 14.4 0.13 12.8 3.0 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Ion_trans PF00520.31 RJW59673.1 - 3.1e-70 236.2 37.8 5.1e-40 137.2 9.4 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 RJW59673.1 - 0.031 12.9 26.7 0.019 13.7 0.5 3.8 4 0 0 4 4 4 0 Polycystin cation channel PsaF PF17550.2 RJW59673.1 - 0.088 12.3 0.3 0.23 10.9 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function LRR_8 PF13855.6 RJW59674.1 - 1.4e-15 56.7 14.1 1.3e-09 37.7 1.4 4.3 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 RJW59674.1 - 4.9e-06 26.8 2.5 0.0019 18.5 0.1 3.1 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RJW59674.1 - 6.1e-06 26.2 0.1 0.03 14.3 0.0 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RJW59674.1 - 0.032 13.7 1.8 0.17 11.4 0.1 2.5 2 1 1 3 3 3 0 Leucine-rich repeat DUF2544 PF11245.8 RJW59674.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2544) LRR_6 PF13516.6 RJW59674.1 - 0.29 11.3 3.4 3.5 7.9 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich repeat CBF PF03914.17 RJW59675.1 - 5.3e-38 130.7 0.0 1.4e-37 129.4 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Adaptin_N PF01602.20 RJW59675.1 - 0.0022 16.6 0.1 0.0054 15.4 0.0 1.6 2 0 0 2 2 2 1 Adaptin N terminal region DnaJ PF00226.31 RJW59676.1 - 1.1e-20 73.6 0.5 1.1e-20 73.6 0.5 2.2 2 0 0 2 2 2 1 DnaJ domain Viral_alk_exo PF01771.17 RJW59676.1 - 0.012 14.5 0.2 0.019 13.8 0.0 1.4 1 1 0 1 1 1 0 Viral alkaline exonuclease EGF_CA PF07645.15 RJW59678.1 - 4.4e-29 100.4 53.9 2.4e-10 40.5 10.0 11.8 9 4 1 10 10 10 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 RJW59678.1 - 1e-15 57.7 52.2 2.3e-08 34.2 4.3 12.4 11 4 1 12 12 12 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RJW59678.1 - 1.3e-11 44.2 83.9 3e-05 23.9 1.1 10.4 9 1 0 9 9 9 7 Complement Clr-like EGF-like hEGF PF12661.7 RJW59678.1 - 0.00029 21.4 129.2 0.001 19.6 3.4 14.1 13 2 0 13 13 13 7 Human growth factor-like EGF EGF_2 PF07974.13 RJW59678.1 - 0.00085 19.6 14.0 0.00085 19.6 14.0 13.0 13 2 0 13 13 13 4 EGF-like domain EGF PF00008.27 RJW59678.1 - 0.0022 18.3 165.1 0.015 15.6 9.4 12.7 13 0 0 13 13 13 7 EGF-like domain EGF_Tenascin PF18720.1 RJW59678.1 - 0.0096 15.9 7.9 0.0096 15.9 7.9 8.9 9 2 0 9 9 9 1 Tenascin EGF domain Guanylate_cyc PF00211.20 RJW59679.1 - 1.6e-63 213.7 0.0 2e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RVT_1 PF00078.27 RJW59680.1 - 4.2e-18 65.7 0.0 5.8e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF_CA PF07645.15 RJW59680.1 - 1.7e-07 31.3 4.3 1.7e-07 31.3 4.3 2.6 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 RJW59680.1 - 7.7e-06 25.7 11.3 0.00011 22.1 0.1 3.0 3 0 0 3 3 3 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RJW59680.1 - 1.1e-05 25.6 4.3 1.1e-05 25.6 4.3 2.6 1 1 1 2 2 2 1 Coagulation Factor Xa inhibitory site hEGF PF12661.7 RJW59680.1 - 0.0001 22.8 26.5 0.0037 17.8 6.3 3.0 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.13 RJW59680.1 - 0.0014 19.0 20.8 0.0031 17.8 11.8 2.8 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 RJW59680.1 - 0.0053 17.0 23.9 0.23 11.8 10.0 2.8 2 0 0 2 2 2 2 EGF-like domain EGF_alliinase PF04863.13 RJW59680.1 - 0.026 14.9 5.0 0.09 13.2 5.0 1.9 1 0 0 1 1 1 0 Alliinase EGF-like domain ANF_receptor PF01094.28 RJW59684.1 - 9e-36 123.7 0.1 4.7e-35 121.3 0.1 1.9 1 1 0 1 1 1 1 Receptor family ligand binding region DUF3939 PF13075.6 RJW59684.1 - 0.0028 17.7 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3939) DUF4794 PF16042.5 RJW59686.1 - 0.1 13.6 0.1 0.15 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4794) Plasmo_rep PF12135.8 RJW59687.1 - 0.021 14.3 1.2 5.7 6.6 0.1 2.3 2 0 0 2 2 2 0 Plasmodium repeat family HAT PF02184.16 RJW59687.1 - 0.12 12.4 0.5 22 5.1 0.0 2.8 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat Sedlin_N PF04628.13 RJW59687.1 - 0.25 11.5 0.0 31 4.7 0.0 2.2 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region T-box PF00907.22 RJW59688.1 - 3.5e-80 268.6 0.7 1e-79 267.1 0.7 1.9 1 0 0 1 1 1 1 T-box PEX11 PF05648.14 RJW59689.1 - 0.065 12.7 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Ras PF00071.22 RJW59690.1 - 2.8e-50 170.1 0.0 3.5e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW59690.1 - 3.4e-31 107.9 0.0 7.6e-31 106.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW59690.1 - 7.2e-11 41.8 0.0 9.9e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW59690.1 - 0.00035 20.0 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RJW59690.1 - 0.00041 20.4 0.0 0.0012 19.0 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 RJW59690.1 - 0.00095 19.5 0.2 0.0093 16.3 0.2 2.3 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.20 RJW59690.1 - 0.001 18.3 1.9 0.72 9.0 0.1 3.0 2 1 0 3 3 3 2 G-protein alpha subunit GTP_EFTU PF00009.27 RJW59690.1 - 0.0032 17.0 0.3 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Pox_A32 PF04665.12 RJW59690.1 - 0.0068 15.9 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein RsgA_GTPase PF03193.16 RJW59690.1 - 0.015 15.2 0.1 3 7.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ArgoMid PF16487.5 RJW59690.1 - 0.031 14.5 0.1 0.057 13.7 0.1 1.5 1 0 0 1 1 1 0 Mid domain of argonaute AAA_7 PF12775.7 RJW59690.1 - 0.033 13.7 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 RJW59690.1 - 0.044 13.7 0.2 0.065 13.1 0.2 1.3 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 RJW59690.1 - 0.047 13.7 0.1 0.11 12.5 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 RJW59690.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 RJW59690.1 - 0.061 13.0 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RJW59690.1 - 0.12 12.8 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 RJW59690.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 RJW59690.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RJW59690.1 - 0.2 12.2 0.0 0.71 10.4 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Mon2_C PF16206.5 RJW59691.1 - 0.15 10.1 0.0 0.19 9.8 0.0 1.0 1 0 0 1 1 1 0 C-terminal region of Mon2 protein APS_kinase PF01583.20 RJW59693.1 - 6.5e-71 237.3 0.0 9.8e-71 236.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 RJW59693.1 - 3.9e-65 219.3 0.0 5.4e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 RJW59693.1 - 1.8e-44 151.2 0.0 2.8e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 RJW59693.1 - 1.3e-05 25.3 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 RJW59693.1 - 0.0014 18.7 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 RJW59693.1 - 0.003 18.1 0.0 0.0055 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 RJW59693.1 - 0.0031 17.0 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 RJW59693.1 - 0.011 15.5 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 RJW59693.1 - 0.065 13.8 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 RJW59693.1 - 0.072 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 RJW59693.1 - 0.2 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 RJW59693.1 - 0.22 11.2 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein GD_AH_C PF04295.13 RJW59695.1 - 0.0056 15.5 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus Nuc_sug_transp PF04142.15 RJW59697.1 - 8.2e-06 25.2 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RJW59697.1 - 0.00043 20.5 20.8 0.00082 19.5 3.3 3.1 4 1 0 4 4 4 2 EamA-like transporter family TPT PF03151.16 RJW59697.1 - 0.0026 17.2 0.1 0.0091 15.4 0.0 1.8 1 1 0 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 RJW59697.1 - 0.058 12.3 8.0 0.12 11.3 5.7 2.5 2 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 RJW59697.1 - 0.15 12.1 1.1 0.3 11.1 0.1 2.0 2 0 0 2 2 2 0 Putative transmembrane family 234 RRXRR PF14239.6 RJW59698.1 - 1.1 9.0 10.8 2.2 8.1 10.8 1.4 1 0 0 1 1 1 0 RRXRR protein Glyco_transf_18 PF15024.6 RJW59701.1 - 8.8e-155 516.5 0.0 2.3e-125 419.4 0.0 3.4 3 1 0 4 4 4 3 Glycosyltransferase family 18 DUF4525 PF15027.6 RJW59701.1 - 0.053 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) HSNSD PF12062.8 RJW59702.1 - 0.081 11.6 0.0 0.087 11.5 0.0 1.0 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase DUF1126 PF06565.12 RJW59703.1 - 5e-100 328.4 0.8 9.2e-36 121.9 0.2 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 RJW59703.1 - 0.0014 19.0 1.7 0.0039 17.6 1.7 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW59703.1 - 0.0087 15.5 3.1 0.055 13.0 0.8 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RJW59703.1 - 0.033 14.1 0.8 0.3 11.1 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain eIF-5_eIF-2B PF01873.17 RJW59703.1 - 0.13 12.2 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 PHTB1_C PF14728.6 RJW59706.1 - 0.098 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus CDC45 PF02724.14 RJW59706.1 - 3.6 5.8 9.2 6.4 4.9 9.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S25 PF03297.15 RJW59707.1 - 6.6e-33 112.9 0.8 1.1e-32 112.2 0.8 1.3 1 0 0 1 1 1 1 S25 ribosomal protein Acetyltransf_3 PF13302.7 RJW59707.1 - 6e-19 69.1 0.0 9.7e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RJW59707.1 - 0.0017 18.6 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 RJW59707.1 - 0.0044 16.7 0.1 0.19 11.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RJW59707.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein CRAL_TRIO PF00650.20 RJW59709.1 - 3.1e-12 46.5 0.1 4.7e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain 7tm_1 PF00001.21 RJW59710.1 - 2.1e-15 56.7 0.1 2.1e-15 56.7 0.1 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Band_7 PF01145.25 RJW59711.1 - 2.8e-29 102.4 0.1 2.8e-29 102.4 0.1 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 RJW59711.1 - 4.2e-26 90.8 2.4 4.2e-26 90.8 2.4 1.8 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 RJW59711.1 - 0.0069 16.1 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family zf-C2H2 PF00096.26 RJW59712.1 - 4.7e-12 45.7 47.4 0.00011 22.4 1.7 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW59712.1 - 1.8e-07 31.4 40.9 0.00069 20.2 0.7 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 RJW59712.1 - 5.1e-06 26.7 22.0 0.0021 18.4 0.8 4.9 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW59712.1 - 0.00022 21.4 0.1 0.00022 21.4 0.1 5.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RJW59712.1 - 0.0089 16.4 3.1 0.0089 16.4 3.1 6.5 7 0 0 7 7 7 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 RJW59712.1 - 0.023 14.4 0.5 0.023 14.4 0.5 3.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 RJW59712.1 - 0.061 13.2 0.1 0.061 13.2 0.1 3.5 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 RJW59712.1 - 0.099 13.0 24.4 0.4 11.0 3.7 4.8 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 RJW59712.1 - 1.3 9.7 8.9 29 5.3 0.2 4.0 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats MarR_2 PF12802.7 RJW59714.1 - 0.081 12.8 0.1 4.6 7.2 0.1 2.5 2 0 0 2 2 2 0 MarR family UQ_con PF00179.26 RJW59715.1 - 2.3e-36 124.6 0.0 3.1e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BK_channel_a PF03493.18 RJW59717.1 - 7e-22 77.5 0.0 5.7e-21 74.5 0.0 2.3 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 RJW59717.1 - 5.9e-09 36.2 0.0 0.00019 21.7 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain RGS-like PF09128.11 RJW59720.1 - 9.3e-11 41.8 0.2 1.8e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain C1_1 PF00130.22 RJW59720.1 - 7.1e-08 32.2 3.8 1.4e-07 31.3 3.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RGS PF00615.19 RJW59720.1 - 0.00067 19.9 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH_16 PF17838.1 RJW59720.1 - 0.079 12.8 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 PH domain C1_2 PF03107.16 RJW59720.1 - 0.54 10.6 4.5 1.2 9.5 4.5 1.6 1 0 0 1 1 1 0 C1 domain Ig_3 PF13927.6 RJW59721.1 - 1.1e-21 77.2 0.5 9.4e-08 32.6 0.0 6.4 6 1 1 7 7 7 4 Immunoglobulin domain I-set PF07679.16 RJW59721.1 - 4.5e-16 58.7 0.0 5.8e-05 23.1 0.0 5.2 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW59721.1 - 6.2e-16 58.5 0.0 9.1e-06 25.9 0.0 6.4 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 RJW59721.1 - 3.6e-14 52.9 1.0 0.01 16.0 0.0 6.9 6 1 1 7 7 7 3 Immunoglobulin V-set domain ig PF00047.25 RJW59721.1 - 3e-12 46.5 0.1 0.00013 22.1 0.0 5.6 5 0 0 5 5 5 3 Immunoglobulin domain Ig_6 PF18452.1 RJW59721.1 - 7.1e-07 28.7 0.0 0.11 12.0 0.0 4.2 4 0 0 4 4 4 2 Immunoglobulin domain Izumo-Ig PF16706.5 RJW59721.1 - 7e-05 22.8 0.0 1.9 8.6 0.0 5.1 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 RJW59721.1 - 0.0072 16.5 0.1 12 6.2 0.0 3.7 4 0 0 4 4 3 1 Immunoglobulin C2-set domain fn3 PF00041.21 RJW59721.1 - 0.02 15.3 6.2 2.1 8.8 0.1 4.2 4 0 0 4 4 4 0 Fibronectin type III domain Stevor PF17410.2 RJW59721.1 - 0.044 13.3 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2369 PF10179.9 RJW59721.1 - 0.34 11.3 2.2 1.6 9.1 1.4 2.5 2 1 0 2 2 1 0 Uncharacterised conserved protein (DUF2369) PDZ PF00595.24 RJW59722.1 - 2e-11 44.1 0.1 4.5e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW59722.1 - 1.5e-09 37.6 0.4 2.9e-09 36.6 0.4 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW59722.1 - 3.9e-05 23.9 0.1 0.00012 22.4 0.1 1.8 2 0 0 2 2 2 1 PDZ domain SH2 PF00017.24 RJW59725.1 - 3.1e-09 36.8 0.0 0.0012 18.9 0.0 2.6 2 0 0 2 2 2 2 SH2 domain SH3_1 PF00018.28 RJW59725.1 - 0.14 11.7 0.0 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 SH3 domain Glyco_transf_18 PF15024.6 RJW59727.1 - 9.2e-128 427.3 0.1 1.2e-112 377.4 0.0 3.2 3 0 0 3 3 3 3 Glycosyltransferase family 18 CD36 PF01130.21 RJW59728.1 - 1.7e-88 297.2 0.2 2.4e-88 296.7 0.2 1.1 1 0 0 1 1 1 1 CD36 family RE_AspBHI_N PF18062.1 RJW59728.1 - 0.16 11.5 0.3 0.28 10.7 0.3 1.3 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal NIF PF03031.18 RJW59729.1 - 3.8e-53 179.4 0.2 5.7e-53 178.9 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Phage_holin_3_5 PF16085.5 RJW59730.1 - 0.0098 16.0 0.4 0.013 15.6 0.4 1.2 1 0 0 1 1 1 1 Bacteriophage holin Hol, superfamily III Pkinase PF00069.25 RJW59731.1 - 5.5e-37 127.6 0.0 6.4e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW59731.1 - 7.8e-14 51.6 0.0 9.2e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW59731.1 - 0.00035 20.0 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RJW59731.1 - 0.0053 16.7 0.1 0.02 14.8 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RJW59731.1 - 0.03 13.7 0.2 0.058 12.7 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RJW59731.1 - 0.035 13.7 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 RJW59731.1 - 0.078 12.6 0.0 0.15 11.6 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Bromodomain PF00439.25 RJW59734.1 - 2.1e-16 59.8 0.0 4e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF3512 PF12024.8 RJW59734.1 - 1.5e-06 27.9 0.0 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) DUF4525 PF15027.6 RJW59735.1 - 0.00017 21.3 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) HTH_AraC PF00165.23 RJW59737.1 - 0.017 15.2 2.1 5.6 7.2 0.2 2.4 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 RJW59737.1 - 0.02 15.1 0.2 7.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Tryp_FSAP PF08248.11 RJW59737.1 - 2.5 8.9 6.8 21 6.0 0.7 2.3 2 0 0 2 2 2 0 Tryptophyllin-3 skin active peptide DUF2890 PF11081.8 RJW59741.1 - 1.6 8.8 6.8 0.7 10.0 3.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) BAG PF02179.16 RJW59742.1 - 4.1e-05 23.9 2.2 5.4e-05 23.6 2.2 1.2 1 0 0 1 1 1 1 BAG domain TolA_bind_tri PF16331.5 RJW59742.1 - 0.035 14.2 1.6 0.06 13.4 0.4 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation Uso1_p115_C PF04871.13 RJW59742.1 - 0.049 14.0 2.9 0.072 13.5 2.9 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region WW PF00397.26 RJW59743.1 - 0.004 17.2 1.0 0.019 15.1 1.2 2.1 1 1 1 2 2 2 1 WW domain RNHCP PF12647.7 RJW59744.1 - 0.0053 16.7 1.1 0.011 15.7 1.1 1.5 1 0 0 1 1 1 1 RNHCP domain DNA_pol3_beta_3 PF02768.15 RJW59745.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain ubiquitin PF00240.23 RJW59746.1 - 2.3e-09 36.9 0.1 4.8e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 RJW59746.1 - 0.0065 16.4 0.2 0.015 15.2 0.1 1.6 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 RJW59746.1 - 0.011 16.2 1.1 0.019 15.4 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain Kelch_1 PF01344.25 RJW59748.1 - 8.2e-64 211.0 17.2 1.1e-13 50.5 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RJW59748.1 - 1.1e-39 133.4 10.4 4.3e-07 30.0 0.2 6.3 3 1 3 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RJW59748.1 - 4.7e-29 100.1 13.4 3.7e-05 23.6 0.1 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 RJW59748.1 - 1.7e-28 98.3 15.7 4.2e-05 23.7 0.3 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 RJW59748.1 - 3.4e-28 98.1 0.4 2.2e-27 95.5 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 RJW59748.1 - 8.3e-18 63.6 13.5 0.023 14.7 0.0 6.5 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 RJW59748.1 - 8.9e-15 54.7 1.0 2.2e-14 53.4 0.1 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 RJW59748.1 - 3.1e-09 36.6 9.1 0.0023 17.9 0.2 5.6 6 0 0 6 6 6 3 Kelch motif Retinin_C PF04527.12 RJW59750.1 - 0.034 14.4 1.3 0.055 13.7 1.3 1.3 1 1 0 1 1 1 0 Drosophila Retinin like protein Ldl_recept_a PF00057.18 RJW59754.1 - 0.0001 22.4 0.9 0.0001 22.4 0.9 2.3 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Shisa PF13908.6 RJW59754.1 - 0.075 13.3 0.0 0.075 13.3 0.0 2.7 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator MDD_C PF18376.1 RJW59756.1 - 3.6e-58 196.4 0.0 5.1e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 RJW59756.1 - 4.1e-05 23.7 3.1 9.3e-05 22.6 3.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Gar1 PF04410.14 RJW59757.1 - 3.4e-35 121.1 0.0 4.3e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region vATP-synt_AC39 PF01992.16 RJW59758.1 - 7.5e-117 390.6 0.3 8.4e-117 390.4 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF758 PF05527.11 RJW59760.1 - 3.3e-42 144.5 0.0 3.8e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Imm75 PF15660.6 RJW59760.1 - 0.054 13.8 0.2 0.23 11.7 0.1 2.1 2 1 0 2 2 2 0 Putative Immunity protein 75 ESR1_C PF12743.7 RJW59761.1 - 0.063 13.1 0.4 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal Coq4 PF05019.13 RJW59763.1 - 6.6e-57 192.4 0.0 8.9e-56 188.7 0.0 2.2 2 1 0 2 2 2 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 CytochromB561_N PF09786.9 RJW59764.1 - 3e-48 165.2 13.7 2.8e-47 162.0 13.7 1.9 1 1 0 1 1 1 1 Cytochrome B561, N terminal Na_Ca_ex PF01699.24 RJW59765.1 - 0.00097 19.1 1.9 0.0017 18.3 1.9 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF296 PF03479.15 RJW59767.1 - 1.5e-25 89.6 1.7 2.6e-25 88.9 1.7 1.4 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain MFA1_2 PF17317.2 RJW59767.1 - 0.17 11.7 0.3 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 Proteasome PF00227.26 RJW59770.1 - 4.6e-47 160.0 0.1 1.7e-46 158.1 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 RJW59770.1 - 3.8e-09 36.1 0.0 7.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RVT_1 PF00078.27 RJW59772.1 - 0.00015 21.4 0.1 0.0045 16.5 0.1 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Nuc_sug_transp PF04142.15 RJW59773.1 - 2.5e-98 329.1 20.2 2.8e-98 328.9 20.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RJW59773.1 - 7.5e-06 26.2 32.5 0.00019 21.6 9.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family Arm PF00514.23 RJW59774.1 - 1.7e-19 69.2 15.7 5.5e-05 23.1 0.2 7.2 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RJW59774.1 - 2.8e-08 33.3 5.4 0.089 13.1 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 RJW59774.1 - 7e-06 26.2 4.2 0.032 14.3 0.3 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RJW59774.1 - 8.1e-05 22.9 9.0 0.72 10.3 0.1 4.7 2 2 4 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 RJW59774.1 - 0.00058 20.3 5.5 6.7 7.3 0.0 5.0 3 1 2 5 5 5 1 HEAT-like repeat CHASE6_C PF17150.4 RJW59774.1 - 0.0017 19.0 3.4 2.9 8.6 0.0 5.2 5 2 0 5 5 5 1 C-terminal domain of two-partite extracellular sensor domain DUF3361 PF11841.8 RJW59774.1 - 0.0018 18.2 3.5 0.038 13.9 2.3 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3361) Arm_2 PF04826.13 RJW59774.1 - 0.0021 17.6 1.5 0.47 9.9 0.1 2.3 1 1 0 2 2 2 2 Armadillo-like Atx10homo_assoc PF09759.9 RJW59774.1 - 0.0041 17.1 1.1 2.8 8.0 0.1 3.8 3 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Rcd1 PF04078.13 RJW59774.1 - 0.0093 15.3 4.5 0.026 13.8 1.5 2.7 1 1 1 3 3 3 1 Cell differentiation family, Rcd1-like Proteasom_PSMB PF10508.9 RJW59774.1 - 0.011 14.3 6.3 0.017 13.7 6.2 1.5 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.8 RJW59774.1 - 0.022 14.8 1.2 30 4.8 0.3 3.5 3 1 0 3 3 3 0 V-ATPase subunit H BtpA PF03437.15 RJW59774.1 - 0.026 13.9 1.4 0.056 12.9 1.4 1.5 2 0 0 2 2 2 0 BtpA family COMMD1_N PF17221.3 RJW59774.1 - 0.048 13.9 0.5 0.29 11.4 0.2 2.4 2 0 0 2 2 2 0 COMMD1 N-terminal domain DNA_alkylation PF08713.11 RJW59774.1 - 0.09 12.5 0.9 28 4.3 0.0 3.6 3 1 1 4 4 4 0 DNA alkylation repair enzyme API5 PF05918.11 RJW59774.1 - 0.099 11.4 4.2 0.17 10.7 3.9 1.5 1 1 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CLASP_N PF12348.8 RJW59774.1 - 0.18 11.4 2.3 2.9 7.4 0.8 3.0 3 0 0 3 3 3 0 CLASP N terminal HEAT_PBS PF03130.16 RJW59774.1 - 0.19 12.5 0.1 0.19 12.5 0.1 3.7 4 1 0 4 4 3 0 PBS lyase HEAT-like repeat Rgp1 PF08737.10 RJW59775.1 - 1.2e-14 54.3 0.0 1e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 Rgp1 Arrestin_N PF00339.29 RJW59775.1 - 0.11 12.6 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DUF2475 PF10629.9 RJW59776.1 - 2.8e-18 65.9 7.2 5.9e-05 23.2 0.1 4.6 4 1 0 4 4 4 4 Protein of unknown function (DUF2475) RabGAP-TBC PF00566.18 RJW59777.1 - 7.9e-46 156.4 0.0 1.3e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Na_Ca_ex PF01699.24 RJW59778.1 - 1.2e-26 93.5 19.0 1.2e-26 93.5 19.0 2.2 2 0 0 2 2 2 1 Sodium/calcium exchanger protein ATP-synt_S1 PF05827.12 RJW59778.1 - 0.14 12.0 1.4 0.28 11.0 1.4 1.4 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) PgaD PF13994.6 RJW59778.1 - 1.2 9.2 5.9 0.15 12.1 1.6 1.7 2 0 0 2 2 2 0 PgaD-like protein DUF2304 PF10066.9 RJW59778.1 - 7.5 6.8 18.5 0.21 11.8 4.4 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) zf-C2H2_12 PF18658.1 RJW59779.1 - 4.5e-07 29.3 1.2 8.9e-07 28.4 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger C2H2-type Thioredoxin PF00085.20 RJW59780.1 - 1.7e-28 98.6 0.1 3.8e-28 97.5 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin zf-Tim10_DDP PF02953.15 RJW59780.1 - 4.2e-16 58.3 2.9 7.8e-16 57.5 2.9 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Thioredoxin_2 PF13098.6 RJW59780.1 - 1e-09 38.8 0.0 2.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RJW59780.1 - 3.8e-07 30.4 0.0 0.0017 18.6 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 RJW59780.1 - 3.2e-06 27.2 0.0 6.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AP4E_app_platf PF14807.6 RJW59780.1 - 0.00075 19.8 1.1 0.41 11.0 0.1 3.1 3 0 0 3 3 3 1 Adaptin AP4 complex epsilon appendage platform OST3_OST6 PF04756.13 RJW59780.1 - 0.0034 16.8 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 RJW59780.1 - 0.0063 16.3 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 RJW59780.1 - 0.0097 15.8 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Rad10 PF03834.14 RJW59780.1 - 0.023 14.7 0.3 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUF570 PF04489.13 RJW59780.1 - 0.031 12.9 0.1 0.053 12.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF570) DUF836 PF05768.14 RJW59780.1 - 0.036 14.5 0.0 0.082 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) HyaE PF07449.11 RJW59780.1 - 0.093 12.7 0.0 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF755 PF05501.11 RJW59780.1 - 0.29 11.4 1.2 0.48 10.7 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) 7tm_1 PF00001.21 RJW59782.1 - 4.3e-28 98.4 28.9 4.3e-28 98.4 28.9 2.7 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) SAM_4 PF18017.1 RJW59783.1 - 5.6e-20 71.1 0.1 9.8e-20 70.3 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5577 PF17740.1 RJW59783.1 - 8.9e-09 35.4 13.3 1.8e-08 34.4 1.4 3.6 2 1 1 3 3 3 2 Family of unknown function (DUF5577) SAM_2 PF07647.17 RJW59783.1 - 1.2e-07 31.7 0.0 2.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RJW59783.1 - 4.8e-05 23.7 0.0 9.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5614 PF18474.1 RJW59783.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5614) PS_Dcarbxylase PF02666.15 RJW59785.1 - 3.9e-56 189.8 0.0 4.8e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Thymidylate_kin PF02223.17 RJW59787.1 - 1.9e-31 109.2 0.0 3.9e-31 108.2 0.0 1.5 1 1 1 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 RJW59787.1 - 0.061 13.6 0.2 0.19 12.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RJW59787.1 - 0.18 12.4 0.1 0.45 11.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain Reprolysin_2 PF13574.6 RJW59788.1 - 2.9e-18 66.5 0.0 8.4e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RJW59788.1 - 4.3e-15 56.4 0.0 4.3e-15 56.4 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Disintegrin PF00200.23 RJW59788.1 - 1.1e-11 45.3 20.0 1.1e-11 45.3 20.0 3.4 3 0 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 RJW59788.1 - 1.2e-09 38.7 0.0 2.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.5 RJW59788.1 - 2.3e-05 24.7 11.0 5.1e-05 23.6 5.8 5.4 4 2 1 5 5 5 2 Membrane-proximal domain, switch, for ADAM17 Reprolysin_4 PF13583.6 RJW59788.1 - 0.00016 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 RJW59788.1 - 0.00078 19.4 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease SRI PF08236.11 RJW59793.1 - 2.4e-16 59.7 0.0 5.5e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 RJW59793.1 - 0.005 16.9 3.5 0.005 16.9 3.5 2.9 3 0 0 3 3 3 1 WW domain DEAD PF00270.29 RJW59796.1 - 3.7e-62 209.2 0.0 5.5e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW59796.1 - 2.4e-25 89.0 0.0 5.1e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 RJW59796.1 - 7.3e-22 77.7 0.4 2.2e-21 76.2 0.1 2.0 3 0 0 3 3 3 1 SPRY domain Ribosom_S12_S23 PF00164.25 RJW59797.1 - 7.7e-51 170.5 0.5 9.9e-51 170.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 RJW59797.1 - 0.098 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Wbp11 PF09429.10 RJW59798.1 - 3.7e-17 62.5 8.6 7.1e-17 61.6 8.6 1.4 1 0 0 1 1 1 1 WW domain binding protein 11 FANC_SAP PF18081.1 RJW59798.1 - 0.42 10.8 1.9 0.52 10.5 0.0 2.2 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain STAR_dimer PF16544.5 RJW59799.1 - 5e-21 74.0 2.0 2e-20 72.1 2.0 2.0 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 RJW59799.1 - 0.0024 17.7 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 KH domain MRP-S31 PF15433.6 RJW59799.1 - 0.015 15.0 5.2 0.024 14.3 5.2 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF3492 PF11997.8 RJW59799.1 - 0.98 9.1 3.6 21 4.8 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3492) Vitellogenin_N PF01347.22 RJW59801.1 - 7.5e-14 51.1 9.7 3.7e-13 48.8 9.7 1.8 1 1 0 1 1 1 1 Lipoprotein amino terminal region 2_5_RNA_ligase2 PF13563.6 RJW59801.1 - 0.031 14.2 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily TPR_1 PF00515.28 RJW59804.1 - 1.2e-31 107.2 6.9 9.9e-11 41.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW59804.1 - 1.6e-24 83.9 5.1 1.8e-08 33.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RJW59804.1 - 1.8e-21 75.5 6.6 2.2e-09 36.9 0.0 3.4 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 RJW59804.1 - 5.1e-20 70.0 6.4 1.4e-07 31.2 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 RJW59804.1 - 6.8e-17 60.2 0.8 1.6e-05 24.6 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RJW59804.1 - 1.5e-14 53.3 6.1 0.00012 22.2 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 RJW59804.1 - 3.3e-13 49.3 0.1 0.00033 21.2 0.1 4.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RJW59804.1 - 8.2e-13 48.4 3.8 6.3e-07 29.6 0.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW59804.1 - 1.3e-07 32.1 0.3 0.00026 21.6 0.6 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW59804.1 - 2.2e-07 31.3 3.4 0.00022 21.7 1.5 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 RJW59804.1 - 2.8e-06 27.4 0.1 0.00013 22.1 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 RJW59804.1 - 4.3e-05 22.9 1.0 0.37 10.0 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RJW59804.1 - 0.00019 21.2 3.2 0.086 12.7 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RJW59804.1 - 0.00026 21.4 3.8 0.31 11.8 0.2 4.0 3 1 1 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RJW59804.1 - 0.00048 20.1 1.2 0.18 11.9 0.2 2.8 2 1 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 RJW59804.1 - 0.0092 14.9 0.6 0.04 12.8 0.6 1.8 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 BTAD PF03704.17 RJW59804.1 - 0.01 16.3 1.3 0.19 12.1 1.2 2.5 1 1 0 1 1 1 0 Bacterial transcriptional activator domain MIT PF04212.18 RJW59804.1 - 0.018 15.1 3.0 1.6 8.8 0.1 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain RVT_1 PF00078.27 RJW59804.1 - 0.019 14.5 0.0 0.059 12.9 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) NRBF2_MIT PF17169.4 RJW59804.1 - 0.048 13.9 1.3 0.15 12.3 0.4 2.4 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 DUF627 PF04781.12 RJW59804.1 - 0.15 12.1 0.2 0.35 10.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TPR_21 PF09976.9 RJW59804.1 - 0.17 11.5 1.2 13 5.5 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 RJW59804.1 - 0.19 11.4 0.6 17 5.1 0.1 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 RJW59804.1 - 0.23 10.9 0.1 0.23 10.9 0.1 3.8 4 0 0 4 4 4 0 SHNi-TPR LRR_6 PF13516.6 RJW59805.1 - 2.9e-12 45.6 10.6 1.4e-05 24.7 0.1 5.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 RJW59805.1 - 0.019 15.4 1.2 1.4e+02 3.7 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 RJW59805.1 - 0.025 15.0 2.9 11 6.6 0.5 3.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW59805.1 - 2.7 7.8 12.5 4.8 7.0 0.8 4.2 4 1 0 4 4 4 0 Leucine rich repeat GATA PF00320.27 RJW59807.1 - 0.014 15.0 0.3 0.032 13.9 0.3 1.6 1 1 0 1 1 1 0 GATA zinc finger Membrane_bind PF14564.6 RJW59808.1 - 0.035 14.5 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Membrane binding PLAC8 PF04749.17 RJW59809.1 - 8.3e-11 42.8 22.5 1.1e-10 42.4 22.5 1.1 1 0 0 1 1 1 1 PLAC8 family zf-CCCH PF00642.24 RJW59810.1 - 9.5e-13 47.7 26.2 3.2e-06 26.9 0.3 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RJW59810.1 - 2.3e-12 46.5 44.9 1.2e-06 28.4 2.0 6.8 6 1 0 6 6 6 3 Zinc finger domain zf-CCCH_4 PF18044.1 RJW59810.1 - 1.1e-08 34.7 4.3 2.5e-05 24.0 0.4 4.9 5 0 0 5 5 5 2 CCCH-type zinc finger Torus PF16131.5 RJW59810.1 - 4.2e-08 33.8 27.8 0.0002 22.0 0.3 5.7 1 1 5 6 6 6 3 Torus domain zf-CCCH_3 PF15663.5 RJW59810.1 - 8.2e-08 32.4 19.7 8.9e-08 32.3 6.5 2.6 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCHC PF00098.23 RJW59810.1 - 4.9e-05 23.2 3.5 4.9e-05 23.2 3.5 3.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCCH_2 PF14608.6 RJW59810.1 - 5.2e-05 23.6 37.9 0.00093 19.6 1.2 5.9 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCHC_4 PF14392.6 RJW59810.1 - 0.22 11.3 8.0 2.4 7.9 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-C3H1 PF10650.9 RJW59810.1 - 1.3 8.8 14.0 1.7 8.4 0.1 4.2 4 0 0 4 4 4 0 Putative zinc-finger domain DUF1677 PF07911.13 RJW59810.1 - 2 8.9 6.7 6.9 7.1 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1677) zf-C2H2_10 PF16588.5 RJW59810.1 - 3.8 7.3 11.7 0.41 10.4 2.0 2.7 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 RJW59810.1 - 4.6 7.3 8.9 0.27 11.2 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle PLAC8 PF04749.17 RJW59811.1 - 1.5e-09 38.7 17.3 2.4e-09 38.1 17.3 1.3 1 0 0 1 1 1 1 PLAC8 family YqhG PF11079.8 RJW59814.1 - 0.046 12.7 0.0 0.095 11.7 0.0 1.4 2 0 0 2 2 2 0 Bacterial protein YqhG of unknown function Helicase_C_2 PF13307.6 RJW59815.1 - 6.3e-54 182.7 0.0 1e-53 182.0 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain zf-RING_5 PF14634.6 RJW59815.1 - 0.04 13.9 5.0 0.087 12.8 5.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 RJW59815.1 - 0.047 13.6 4.8 0.11 12.3 4.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW59815.1 - 0.14 12.0 4.8 0.27 11.1 4.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW59815.1 - 0.3 10.9 4.3 0.76 9.7 4.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RJW59815.1 - 0.98 9.3 5.7 2.2 8.2 5.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DBC1 PF14443.6 RJW59816.1 - 3.4e-45 153.0 0.0 9e-45 151.7 0.0 1.8 1 0 0 1 1 1 1 DBC1 SAP PF02037.27 RJW59816.1 - 1.4e-09 37.5 0.4 3.6e-09 36.1 0.4 1.8 1 0 0 1 1 1 1 SAP domain Exonuc_VII_L PF02601.15 RJW59816.1 - 5.9 6.4 16.1 2.7 7.5 7.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Myelin_PLP PF01275.19 RJW59817.1 - 2.1e-23 83.4 15.3 1e-19 71.4 13.1 2.1 2 0 0 2 2 2 2 Myelin proteolipid protein (PLP or lipophilin) BTG PF07742.12 RJW59818.1 - 1e-30 105.9 0.0 4.2e-30 104.0 0.0 1.9 2 0 0 2 2 2 1 BTG family Lipase_GDSL_2 PF13472.6 RJW59819.1 - 2.1e-19 70.6 0.0 3e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RJW59819.1 - 3.1e-18 66.5 0.0 4.4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FerA PF08165.11 RJW59819.1 - 0.091 12.7 0.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 FerA (NUC095) domain EF-hand_1 PF00036.32 RJW59820.1 - 1.8e-08 33.4 0.0 0.0057 16.1 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW59820.1 - 3.1e-07 30.8 0.0 5.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW59820.1 - 5.2e-07 29.1 0.1 0.02 14.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RJW59820.1 - 0.00013 21.3 0.1 0.00033 20.0 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 RJW59820.1 - 0.00085 19.1 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 RJW59820.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EGF_CA PF07645.15 RJW59823.1 - 2.7e-08 33.9 26.7 1e-06 28.8 6.6 6.6 6 3 1 7 7 7 2 Calcium-binding EGF domain cEGF PF12662.7 RJW59823.1 - 0.002 18.0 2.5 0.002 18.0 2.5 5.8 6 0 0 6 6 6 2 Complement Clr-like EGF-like Glyco_transf_21 PF13506.6 RJW59826.1 - 3.5e-39 134.0 0.1 9.8e-20 70.7 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 RJW59826.1 - 2.2e-15 57.2 0.0 3.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 RJW59826.1 - 8.2e-06 25.9 6.7 8.2e-06 25.9 6.7 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 RJW59826.1 - 0.0054 16.5 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Auxin_repressed PF05564.12 RJW59827.1 - 2.7 8.7 8.9 0.38 11.5 0.3 3.4 2 1 2 4 4 4 0 Dormancy/auxin associated protein ADK PF00406.22 RJW59828.1 - 4.1e-103 341.8 0.0 1.4e-19 70.7 0.0 6.4 6 0 0 6 6 6 6 Adenylate kinase AAA_17 PF13207.6 RJW59828.1 - 2.7e-50 170.3 0.0 1.3e-08 35.3 0.0 7.4 7 0 0 7 7 6 6 AAA domain AAA_33 PF13671.6 RJW59828.1 - 1.4e-33 116.1 0.0 1.5e-06 28.5 0.0 7.1 7 0 0 7 7 6 6 AAA domain AAA_18 PF13238.6 RJW59828.1 - 2.2e-25 89.7 0.6 0.0045 17.5 0.0 8.0 7 1 0 7 7 6 5 AAA domain AAA PF00004.29 RJW59828.1 - 9.9e-25 87.5 0.6 0.0062 17.0 0.0 6.4 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RJW59828.1 - 1.1e-23 84.3 1.3 0.0036 17.6 0.0 6.9 7 0 0 7 7 6 5 AAA domain NACHT PF05729.12 RJW59828.1 - 2e-16 60.3 5.9 0.17 11.8 0.0 6.6 6 0 0 6 6 6 5 NACHT domain AAA_24 PF13479.6 RJW59828.1 - 1.8e-15 57.2 0.2 0.82 9.4 0.0 6.4 6 0 0 6 6 6 5 AAA domain Hydin_ADK PF17213.3 RJW59828.1 - 4e-13 50.1 0.0 0.74 10.1 0.0 7.4 7 0 0 7 7 7 2 Hydin Adenylate kinase-like domain KTI12 PF08433.10 RJW59828.1 - 1.1e-12 48.0 0.8 0.79 9.1 0.0 6.3 6 0 0 6 6 6 2 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 RJW59828.1 - 1.4e-12 47.7 0.0 0.28 11.3 0.0 6.7 7 0 0 7 7 6 2 50S ribosome-binding GTPase SKI PF01202.22 RJW59828.1 - 1.1e-11 45.1 0.1 1.3 9.2 0.0 6.1 6 0 0 6 6 6 3 Shikimate kinase AAA_16 PF13191.6 RJW59828.1 - 4.7e-11 43.4 0.0 1.8 8.9 0.0 7.2 7 0 0 7 7 7 1 AAA ATPase domain Roc PF08477.13 RJW59828.1 - 6e-10 39.4 6.2 0.11 12.8 0.0 6.3 6 0 0 6 6 6 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 RJW59828.1 - 8.2e-10 38.4 0.9 2.7 7.3 0.0 6.2 6 0 0 6 6 6 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 RJW59828.1 - 1e-09 39.0 0.4 3.2 8.3 0.0 6.5 6 0 0 6 6 6 1 ABC transporter RNA_helicase PF00910.22 RJW59828.1 - 2.5e-09 37.5 5.3 3.3 8.1 0.1 7.0 6 1 0 6 6 6 0 RNA helicase SRPRB PF09439.10 RJW59828.1 - 3.2e-09 36.5 0.6 1.3 8.4 0.0 6.1 6 0 0 6 6 6 1 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.17 RJW59828.1 - 2.1e-08 34.1 0.3 1.5 8.5 0.0 6.0 6 0 0 6 6 6 1 IstB-like ATP binding protein TsaE PF02367.17 RJW59828.1 - 2.8e-08 33.8 0.0 7.7 6.5 0.0 6.3 6 0 0 6 6 6 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 RJW59828.1 - 4.6e-08 33.0 0.0 2 8.1 0.0 5.9 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain 6PF2K PF01591.18 RJW59828.1 - 5.5e-08 32.4 0.0 0.084 12.2 0.0 5.5 6 0 0 6 6 6 2 6-phosphofructo-2-kinase AAA_5 PF07728.14 RJW59828.1 - 6.8e-08 32.6 3.0 14 5.7 0.0 7.5 7 0 0 7 7 7 0 AAA domain (dynein-related subfamily) TniB PF05621.11 RJW59828.1 - 7.2e-08 32.1 0.0 2 7.8 0.0 6.1 6 0 0 6 6 6 2 Bacterial TniB protein AAA_22 PF13401.6 RJW59828.1 - 7.6e-08 32.7 0.4 13 6.1 0.0 6.6 6 0 0 6 6 6 0 AAA domain Zeta_toxin PF06414.12 RJW59828.1 - 3.4e-07 29.7 0.0 0.82 8.9 0.0 5.7 6 0 0 6 6 6 1 Zeta toxin Arf PF00025.21 RJW59828.1 - 2.2e-06 27.3 0.0 5.3 6.5 0.0 5.9 6 0 0 6 6 6 0 ADP-ribosylation factor family PduV-EutP PF10662.9 RJW59828.1 - 2.7e-06 27.2 7.5 1.2 8.8 0.1 5.8 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation Ploopntkinase3 PF18751.1 RJW59828.1 - 4.6e-06 26.7 0.1 31 4.4 0.0 6.1 6 0 0 6 6 6 0 P-loop Nucleotide Kinase3 dNK PF01712.19 RJW59828.1 - 3.5e-05 23.8 0.8 2.4 8.0 0.0 5.7 6 0 0 6 6 5 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 RJW59828.1 - 3.9e-05 23.4 0.2 1.5 8.5 0.0 5.5 6 0 0 6 6 5 1 Thymidylate kinase FeoB_N PF02421.18 RJW59828.1 - 0.00014 21.4 2.0 18 4.8 0.0 6.1 6 0 0 6 6 6 0 Ferrous iron transport protein B AAA_7 PF12775.7 RJW59828.1 - 0.00022 20.8 0.0 42 3.6 0.0 5.6 6 0 0 6 6 6 0 P-loop containing dynein motor region AAA_25 PF13481.6 RJW59828.1 - 0.00023 20.8 3.9 41 3.7 0.1 6.8 8 0 0 8 8 6 0 AAA domain AAA_30 PF13604.6 RJW59828.1 - 0.00028 20.7 0.1 36 4.0 0.0 5.3 6 0 0 6 6 5 0 AAA domain AAA_29 PF13555.6 RJW59828.1 - 0.00033 20.3 0.0 2.8 7.7 0.0 4.7 5 0 0 5 5 5 1 P-loop containing region of AAA domain RET_CLD4 PF17813.1 RJW59828.1 - 0.0012 19.1 0.2 6.9 7.0 0.0 5.0 4 1 1 5 5 4 0 RET Cadherin like domain 4 G-alpha PF00503.20 RJW59828.1 - 0.0013 17.9 0.1 2.3 7.3 0.0 3.9 4 0 0 4 4 4 1 G-protein alpha subunit Cytidylate_kin PF02224.18 RJW59828.1 - 0.0013 18.5 0.6 17 5.0 0.0 4.5 5 0 0 5 5 4 0 Cytidylate kinase CPT PF07931.12 RJW59828.1 - 0.0021 17.9 0.0 30 4.4 0.0 4.9 6 0 0 6 6 4 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.13 RJW59828.1 - 0.0035 16.6 0.0 14 4.8 0.0 4.6 6 0 0 6 6 5 0 TIP49 P-loop domain NTPase_1 PF03266.15 RJW59828.1 - 0.0044 16.9 4.6 35 4.2 0.0 5.8 6 0 0 6 6 6 0 NTPase MobB PF03205.14 RJW59828.1 - 0.0059 16.5 6.9 2.8 7.8 0.0 5.9 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 RJW59828.1 - 0.0083 16.2 0.5 64 3.6 0.0 5.0 6 0 0 6 6 4 0 AAA domain RsgA_GTPase PF03193.16 RJW59828.1 - 0.014 15.3 0.0 14 5.5 0.0 4.4 6 0 0 6 6 5 0 RsgA GTPase Alpha_L_fucos PF01120.17 RJW59828.1 - 0.028 13.9 0.2 8.8 5.7 0.0 3.1 4 0 0 4 4 2 0 Alpha-L-fucosidase AAA_23 PF13476.6 RJW59828.1 - 0.033 14.7 0.6 2.2e+02 2.2 0.0 4.7 5 0 0 5 5 4 0 AAA domain Pox_A32 PF04665.12 RJW59828.1 - 0.038 13.4 0.0 81 2.5 0.0 4.5 5 0 0 5 5 4 0 Poxvirus A32 protein AAA_3 PF07726.11 RJW59828.1 - 0.04 13.8 0.1 83 3.0 0.0 4.7 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 RJW59828.1 - 0.05 12.9 1.5 9.3 5.4 0.0 4.1 5 0 0 5 5 4 0 Septin RasGEF_N_2 PF14663.6 RJW59828.1 - 0.1 13.0 0.0 40 4.7 0.0 4.3 5 1 1 6 6 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain APS_kinase PF01583.20 RJW59828.1 - 0.24 11.3 0.4 19 5.1 0.0 3.9 5 0 0 5 5 4 0 Adenylylsulphate kinase IPT PF01745.16 RJW59828.1 - 0.39 10.1 4.0 13 5.1 0.0 4.2 5 0 0 5 5 4 0 Isopentenyl transferase Rad17 PF03215.15 RJW59828.1 - 0.96 9.3 2.8 26 4.7 0.2 3.6 4 0 0 4 4 3 0 Rad17 P-loop domain Ribosomal_L37e PF01907.19 RJW59828.1 - 9.8 6.4 10.7 7.8 6.7 2.3 4.1 4 0 0 4 4 3 0 Ribosomal protein L37e Ank_2 PF12796.7 RJW59829.1 - 3.3e-22 78.9 0.6 6e-10 39.6 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW59829.1 - 2.1e-17 63.2 0.2 2.3e-06 28.0 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW59829.1 - 2.5e-16 59.5 1.0 7e-07 29.4 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW59829.1 - 9.6e-14 50.2 0.3 0.002 18.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 RJW59829.1 - 2e-10 40.6 5.9 0.11 13.0 0.0 5.1 4 1 0 4 4 4 4 Ankyrin repeat PDZ_6 PF17820.1 RJW59829.1 - 9e-10 38.3 0.0 2.5e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW59829.1 - 1.3e-09 38.3 0.0 2.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW59829.1 - 2.8e-05 24.3 0.1 0.00012 22.3 0.0 2.1 2 0 0 2 2 2 1 PDZ domain CfAFP PF05264.11 RJW59830.1 - 0.15 12.0 0.8 0.32 11.0 0.8 1.4 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) WD40 PF00400.32 RJW59832.1 - 9.6e-07 29.4 7.5 0.011 16.5 0.8 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.6 RJW59832.1 - 1.2 9.7 6.7 1.5 9.4 0.0 3.7 4 1 0 4 4 4 0 PQQ-like domain zf-LITAF-like PF10601.9 RJW59833.1 - 3.7e-07 30.3 0.2 4.8e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DUF2561 PF10812.8 RJW59833.1 - 0.0059 16.7 0.0 0.0059 16.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Tim17 PF02466.19 RJW59834.1 - 3.5e-12 46.7 0.0 5.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Solute_trans_a PF03619.16 RJW59836.1 - 1.6e-33 116.4 2.8 2.1e-33 116.0 2.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SH3_9 PF14604.6 RJW59837.1 - 9.3e-46 153.5 2.2 2.4e-12 46.5 0.0 4.6 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 RJW59837.1 - 3.3e-43 145.0 0.1 1.9e-13 49.8 0.0 4.4 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 RJW59837.1 - 8.8e-38 127.8 0.1 2.5e-09 36.6 0.0 4.7 5 0 0 5 5 5 4 Variant SH3 domain RhoGEF PF00621.20 RJW59837.1 - 3.4e-34 118.7 1.5 8.5e-34 117.4 1.5 1.7 1 0 0 1 1 1 1 RhoGEF domain EF-hand_4 PF12763.7 RJW59837.1 - 2.5e-26 91.6 0.0 2.7e-12 46.6 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand PH_13 PF16652.5 RJW59837.1 - 1.8e-07 31.1 5.5 7.6e-07 29.1 0.0 3.0 3 0 0 3 3 2 1 Pleckstrin homology domain EF-hand_1 PF00036.32 RJW59837.1 - 1.9e-07 30.1 3.0 0.019 14.5 0.1 3.5 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 RJW59837.1 - 1.5e-06 28.6 0.0 0.0019 18.6 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW59837.1 - 3.1e-05 23.7 1.0 0.18 11.7 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW59837.1 - 7e-05 22.5 4.1 1.6 8.8 0.1 5.0 5 0 0 5 5 5 1 EF-hand domain EF-hand_5 PF13202.6 RJW59837.1 - 0.0048 16.3 1.3 0.21 11.2 0.1 2.9 3 0 0 3 3 3 1 EF hand Ank_2 PF12796.7 RJW59840.1 - 3.3e-36 123.7 0.5 9.6e-16 58.2 0.2 4.6 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW59840.1 - 6.4e-35 119.1 5.5 1.3e-09 38.4 0.6 6.4 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 RJW59840.1 - 2.3e-21 75.2 14.8 0.00014 22.1 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 RJW59840.1 - 5.3e-21 74.4 13.8 4.3e-09 36.5 0.8 7.8 4 2 5 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW59840.1 - 1.2e-20 71.4 9.2 0.027 15.0 0.1 8.4 8 0 0 8 8 8 6 Ankyrin repeat SPATA48 PF15073.6 RJW59842.1 - 5.3e-13 49.4 0.7 5.3e-13 49.4 0.7 1.7 2 0 0 2 2 2 1 Spermatogenesis-associated protein 48 Aminotran_1_2 PF00155.21 RJW59842.1 - 0.04 13.1 0.0 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Kinesin PF00225.23 RJW59843.1 - 1.5e-74 250.9 1.2 4.4e-74 249.4 1.2 1.9 1 0 0 1 1 1 1 Kinesin motor domain Seryl_tRNA_N PF02403.22 RJW59843.1 - 0.016 15.4 4.5 0.016 15.4 4.5 5.3 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 RJW59843.1 - 0.047 13.0 51.2 0.034 13.5 6.8 4.4 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 RJW59843.1 - 0.14 12.2 43.1 0.026 14.6 7.8 4.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein EP400_N PF15790.5 RJW59843.1 - 3 6.6 6.5 1.1 8.1 2.7 1.9 1 1 1 2 2 2 0 E1A-binding protein p400, N-terminal CENP-F_leu_zip PF10473.9 RJW59843.1 - 4.1 7.4 58.6 0.55 10.3 6.8 5.5 2 2 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 RJW59843.1 - 4.5 7.3 26.8 0.21 11.7 2.1 4.9 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 RJW59843.1 - 5.2 6.9 23.7 4.4 7.1 2.8 4.5 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF4055 PF13264.6 RJW59843.1 - 5.9 7.0 6.7 2.4 8.3 1.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) Cnn_1N PF07989.11 RJW59843.1 - 6.5 7.0 36.0 0.28 11.4 0.3 6.2 4 2 2 6 6 6 0 Centrosomin N-terminal motif 1 V_ATPase_I PF01496.19 RJW59843.1 - 9.1 4.1 27.4 2.3 6.0 4.0 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CUB PF00431.20 RJW59845.1 - 3.5e-43 146.4 0.7 1.3e-21 77.0 0.0 2.3 2 0 0 2 2 2 2 CUB domain IL12p40_C PF10420.9 RJW59845.1 - 0.065 13.8 0.4 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus CUB PF00431.20 RJW59847.1 - 1.7e-45 153.9 0.0 7.2e-22 77.8 0.1 2.4 2 0 0 2 2 2 2 CUB domain RVT_1 PF00078.27 RJW59848.1 - 2.6e-06 27.1 0.0 5.6e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2163 PF09931.9 RJW59848.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) RIO1 PF01163.22 RJW59849.1 - 2.3e-55 187.1 0.0 4.4e-47 160.1 0.0 2.4 2 0 0 2 2 2 2 RIO1 family RVT_1 PF00078.27 RJW59849.1 - 5.3e-32 111.1 0.0 9.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 RJW59851.1 - 2.6e-16 59.8 0.0 6.3e-16 58.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) E1_DerP2_DerF2 PF02221.15 RJW59851.1 - 0.02 15.4 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 ML domain DUF4679 PF15728.5 RJW59852.1 - 0.015 14.3 0.3 0.017 14.2 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) DHC PF09626.10 RJW59852.1 - 0.032 15.1 0.1 0.044 14.7 0.1 1.3 1 0 0 1 1 1 0 Dihaem cytochrome c RWD PF05773.22 RJW59853.1 - 3.4e-14 53.1 0.0 6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 RJW59853.1 - 6.8e-06 26.5 4.9 2.1e-05 24.9 4.7 1.8 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 Peptidase_M24 PF00557.24 RJW59853.1 - 0.058 13.1 0.5 0.11 12.2 0.5 1.6 1 1 0 1 1 1 0 Metallopeptidase family M24 ZapB PF06005.12 RJW59853.1 - 0.13 12.7 9.5 3.4 8.2 9.5 2.4 1 1 0 1 1 1 0 Cell division protein ZapB DUF4167 PF13763.6 RJW59853.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) CUB PF00431.20 RJW59854.1 - 8.1e-32 109.8 0.2 2.3e-24 85.8 0.1 2.0 2 0 0 2 2 2 2 CUB domain CUB PF00431.20 RJW59856.1 - 9.7e-38 128.9 0.2 4.6e-13 49.5 0.0 4.1 3 2 0 3 3 3 3 CUB domain RRM_1 PF00076.22 RJW59857.1 - 2.1e-16 59.5 0.1 3.7e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW59857.1 - 0.0002 21.4 0.0 0.00057 20.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 RJW59857.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CW PF07496.15 RJW59858.1 - 0.0029 17.6 0.9 3.7 7.6 0.1 2.9 2 0 0 2 2 2 2 CW-type Zinc Finger DUF2423 PF10338.9 RJW59858.1 - 0.43 10.9 3.8 26 5.2 0.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2423) Ion_trans PF00520.31 RJW59859.1 - 8.2e-27 94.0 14.8 2.7e-26 92.3 14.8 1.7 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW59859.1 - 7.5e-09 35.4 3.8 7.5e-09 35.4 3.8 1.9 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 RJW59859.1 - 0.023 13.4 7.0 0.046 12.4 7.0 1.4 1 1 0 1 1 1 0 Polycystin cation channel Ribosomal_S18 PF01084.20 RJW59862.1 - 8.1e-19 67.6 0.0 1.7e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 SH3_1 PF00018.28 RJW59863.1 - 6.7e-05 22.4 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF3829 PF12889.7 RJW59863.1 - 0.0048 16.4 2.5 0.014 14.9 2.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3829) GAS PF13851.6 RJW59863.1 - 0.028 13.8 3.3 0.12 11.7 0.6 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Zwint PF15556.6 RJW59863.1 - 0.15 11.6 0.5 0.26 10.8 0.5 1.3 1 0 0 1 1 1 0 ZW10 interactor DUF4446 PF14584.6 RJW59863.1 - 0.27 11.2 5.0 0.24 11.4 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CorA PF01544.18 RJW59863.1 - 0.5 9.6 4.4 0.83 8.9 4.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein API5 PF05918.11 RJW59864.1 - 4e-96 322.9 0.0 5.2e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 RJW59864.1 - 0.0082 16.5 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats Nod1 PF17114.5 RJW59864.1 - 0.064 13.4 0.5 0.064 13.4 0.5 2.2 2 1 1 3 3 3 0 Gef2-related medial cortical node protein Nod1 Thioredoxin PF00085.20 RJW59867.1 - 4.2e-11 42.8 0.0 8.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin RVT_1 PF00078.27 RJW59867.1 - 0.0036 16.9 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1673 PF07895.11 RJW59867.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) TraF PF13728.6 RJW59867.1 - 0.063 13.1 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Pkinase PF00069.25 RJW59869.1 - 4.6e-25 88.5 0.0 7.5e-24 84.5 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW59869.1 - 9e-16 57.9 0.0 7.5e-15 54.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW59869.1 - 8e-06 25.4 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW59869.1 - 0.013 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RJW59869.1 - 0.017 15.1 0.4 0.035 14.0 0.4 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RJW59869.1 - 0.31 10.4 2.6 0.14 11.5 0.2 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5600 PF18150.1 RJW59872.1 - 2e-42 144.1 0.7 4.7e-42 142.9 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EHD_N PF16880.5 RJW59872.1 - 2.2e-15 56.2 0.7 2.2e-15 56.2 0.7 1.8 2 0 0 2 2 2 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 RJW59872.1 - 1.3e-14 54.6 0.0 4.2e-14 52.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RJW59872.1 - 3.4e-09 36.8 0.0 7.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RJW59872.1 - 0.00054 19.5 0.0 0.0028 17.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RJW59872.1 - 0.0086 16.0 0.2 1.1 9.2 0.2 2.8 2 1 1 3 3 3 1 RsgA GTPase Roc PF08477.13 RJW59872.1 - 0.04 14.1 0.0 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 RJW59872.1 - 0.05 13.1 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 RJW59872.1 - 0.07 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Siah-Interact_N PF09032.11 RJW59872.1 - 1.5 9.1 0.0 1.5 9.1 0.0 2.6 4 0 0 4 4 4 0 Siah interacting protein, N terminal ChaC PF04752.12 RJW59873.1 - 1.4e-37 129.4 0.1 9.2e-37 126.8 0.1 1.9 1 1 0 1 1 1 1 ChaC-like protein Oxysterol_BP PF01237.18 RJW59874.1 - 5e-125 417.2 0.0 6.8e-125 416.8 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_6 PF15406.6 RJW59874.1 - 8.2e-05 22.9 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 RJW59874.1 - 0.0018 18.8 0.0 0.01 16.3 0.0 2.2 2 0 0 2 2 2 1 PH domain KCNQ2_u3 PF16642.5 RJW59874.1 - 0.1 13.6 3.9 0.39 11.7 0.2 3.0 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Pyr_redox_2 PF07992.14 RJW59875.1 - 1.3e-70 238.0 0.8 1.6e-70 237.6 0.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RJW59875.1 - 8.8e-38 129.0 0.0 3.1e-37 127.2 0.0 2.0 2 1 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RJW59875.1 - 6.9e-20 71.4 6.1 2.6e-17 63.1 1.6 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RJW59875.1 - 3.6e-11 43.1 9.4 2e-09 37.3 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RJW59875.1 - 5.5e-10 39.0 1.1 6.1e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RJW59875.1 - 1.9e-09 37.1 2.4 1.1e-07 31.3 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 RJW59875.1 - 1.1e-07 31.9 1.3 0.00016 21.9 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RJW59875.1 - 3.7e-07 29.6 0.9 3.7e-07 29.6 0.9 3.1 4 0 0 4 4 4 1 FAD binding domain FAD_binding_3 PF01494.19 RJW59875.1 - 9.3e-06 25.1 6.9 0.023 14.0 0.5 3.2 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 RJW59875.1 - 0.00013 21.4 2.0 0.12 11.6 0.3 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 RJW59875.1 - 0.00025 19.9 9.3 0.0012 17.6 0.7 3.6 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.17 RJW59875.1 - 0.00061 19.1 1.9 0.0028 16.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 RJW59875.1 - 0.002 17.3 0.7 0.9 8.6 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 RJW59875.1 - 0.12 11.7 0.2 8.2 5.7 0.1 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RJW59875.1 - 0.13 11.8 8.7 1.8 8.1 1.8 3.4 3 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 RJW59875.1 - 0.38 10.3 9.1 3.9 6.9 0.6 3.4 3 1 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RJW59875.1 - 0.78 8.7 4.3 1.7 7.6 0.3 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 RJW59875.1 - 6.6 6.6 7.4 2 8.3 0.7 3.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.32 RJW59876.1 - 3e-32 110.1 22.8 7.8e-05 23.4 0.1 12.4 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW59876.1 - 1.7e-13 50.7 0.0 0.22 11.8 0.0 6.4 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW59876.1 - 0.00099 17.9 1.1 0.022 13.4 0.0 3.4 5 1 0 5 5 5 1 Nucleoporin Nup120/160 eIF2A PF08662.11 RJW59876.1 - 0.0013 18.7 0.0 0.85 9.5 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Hydrolase_4 PF12146.8 RJW59878.1 - 8.4e-05 21.9 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RJW59878.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ldr_toxin PF13940.6 RJW59878.1 - 0.12 12.4 0.1 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system Metallophos PF00149.28 RJW59881.1 - 2.1e-38 132.9 0.1 2.7e-38 132.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RJW59881.1 - 6e-20 71.4 1.5 1.3e-19 70.4 0.7 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF4013 PF13197.6 RJW59882.1 - 1.6e-05 24.9 0.0 0.026 14.4 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF4013) ChaB PF06150.12 RJW59882.1 - 2.8e-05 24.6 0.6 7.8 7.2 0.0 3.2 3 0 0 3 3 3 3 ChaB Ribosomal_L22 PF00237.19 RJW59882.1 - 7.8e-05 22.8 0.1 4.7 7.5 0.0 3.2 3 0 0 3 3 3 2 Ribosomal protein L22p/L17e HTH_AraC PF00165.23 RJW59882.1 - 0.00013 21.9 12.4 1 9.6 0.5 3.6 3 0 0 3 3 3 3 Bacterial regulatory helix-turn-helix proteins, AraC family VHL PF01847.16 RJW59882.1 - 0.003 17.5 0.0 17 5.4 0.0 3.1 3 0 0 3 3 3 0 VHL beta domain Flavi_NS4B PF01349.17 RJW59882.1 - 0.0033 16.8 1.1 15 4.9 0.1 3.2 3 0 0 3 3 3 2 Flavivirus non-structural protein NS4B DUF4844 PF16133.5 RJW59882.1 - 0.0047 17.5 0.0 31 5.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4844) DUF3931 PF13082.6 RJW59882.1 - 0.028 14.6 0.6 12 6.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3931) UPF0715 PF17094.5 RJW59882.1 - 0.23 12.0 6.3 12 6.5 0.9 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0715) Filament_head PF04732.14 RJW59882.1 - 2.4 9.1 11.7 22 6.0 0.6 3.2 2 1 1 3 3 3 0 Intermediate filament head (DNA binding) region HTH_18 PF12833.7 RJW59882.1 - 2.9 8.2 9.6 49 4.3 0.3 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain TPR_8 PF13181.6 RJW59885.1 - 9.6e-05 22.3 0.3 0.00019 21.4 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW59885.1 - 0.00023 21.0 0.1 0.00046 20.1 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 RJW59885.1 - 0.00024 20.8 0.8 0.00041 20.0 0.8 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 RJW59885.1 - 0.0027 18.2 0.1 0.006 17.2 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW59885.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 RJW59885.1 - 0.033 14.5 0.0 0.049 13.9 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_S19e PF01090.19 RJW59885.1 - 0.057 13.1 0.1 0.078 12.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e TPR_19 PF14559.6 RJW59885.1 - 0.1 13.1 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-CRD PF17979.1 RJW59888.1 - 6.2e-26 91.4 8.3 6.2e-26 91.4 8.3 2.5 1 1 1 2 2 2 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 RJW59888.1 - 1.1e-10 41.7 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-CCHH PF10283.9 RJW59888.1 - 1.8e-05 24.6 3.2 3.8e-05 23.6 3.2 1.6 1 0 0 1 1 1 1 PBZ domain zf-C3HC4_2 PF13923.6 RJW59888.1 - 6.7e-05 22.6 15.6 6.7e-05 22.6 15.6 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW59888.1 - 0.0001 22.1 15.4 0.0001 22.1 15.4 4.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW59888.1 - 0.0035 17.6 17.4 0.0035 17.6 17.4 4.5 5 1 0 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 RJW59888.1 - 0.004 17.0 15.0 0.004 17.0 15.0 3.9 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 RJW59888.1 - 0.0061 16.6 1.7 0.0061 16.6 1.7 4.6 4 1 1 5 5 5 1 Double zinc ribbon Yop-YscD_cpl PF16697.5 RJW59888.1 - 0.1 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.7 RJW59888.1 - 0.1 12.7 8.3 0.49 10.5 8.3 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger NICE-3 PF07406.11 RJW59890.1 - 2.3e-26 92.9 0.0 4.1e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 NICE-3 protein EPF PF17181.4 RJW59890.1 - 0.088 12.8 1.1 0.43 10.6 0.1 2.5 2 0 0 2 2 2 0 Epidermal patterning factor proteins UcrQ PF02939.16 RJW59894.1 - 7.4e-28 96.3 0.1 7.7e-28 96.3 0.1 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 RJW59894.1 - 0.00019 21.8 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Ephrin_rec_like PF07699.13 RJW59895.1 - 1.1e-06 28.2 6.9 1.4e-05 24.8 3.9 8.0 6 2 2 8 8 8 4 Putative ephrin-receptor like Flag1_repress PF03614.13 RJW59895.1 - 0.053 13.3 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Repressor of phase-1 flagellin TNFR_c6 PF00020.18 RJW59895.1 - 0.76 10.2 0.0 0.76 10.2 0.0 8.4 7 2 2 9 9 9 0 TNFR/NGFR cysteine-rich region Peptidase_C1 PF00112.23 RJW59896.1 - 2.4e-10 40.9 0.0 4.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW59896.1 - 1e-05 25.9 7.1 1e-05 25.9 7.1 1.9 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Retrotrans_gag PF03732.17 RJW59896.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein SecE PF00584.20 RJW59898.1 - 0.29 11.1 2.6 5.2 7.1 0.2 2.9 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex ChaC PF04752.12 RJW59899.1 - 2.9e-49 167.5 0.0 7.3e-49 166.2 0.0 1.6 1 1 0 1 1 1 1 ChaC-like protein RRM_1 PF00076.22 RJW59900.1 - 1.2e-16 60.3 0.1 6.3e-08 32.3 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RJW59900.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Frag1 PF10277.9 RJW59902.1 - 6.7e-05 22.5 0.2 6.9e-05 22.5 0.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family FG-GAP PF01839.23 RJW59903.1 - 2.9e-18 65.7 17.6 1.2e-07 31.7 0.5 3.8 3 0 0 3 3 3 3 FG-GAP repeat Integrin_alpha2 PF08441.12 RJW59903.1 - 6.9e-18 64.8 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Integrin alpha VCBS PF13517.6 RJW59903.1 - 4.3e-11 43.2 2.5 2.2e-05 24.9 0.2 3.1 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Glycos_transf_2 PF00535.26 RJW59904.1 - 9.4e-18 64.6 0.0 1.5e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 RJW59904.1 - 2.2e-06 27.2 0.0 4.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RJW59904.1 - 0.00025 20.6 0.0 0.53 9.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 RJW59904.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ProRS-C_1 PF09180.11 RJW59905.1 - 0.07 13.3 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal HTH_6 PF01418.17 RJW59905.1 - 0.084 12.9 0.3 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family AhpC-TSA PF00578.21 RJW59906.1 - 4.9e-38 129.8 0.0 6.2e-38 129.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RJW59906.1 - 2.9e-15 56.3 0.0 3.5e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RJW59906.1 - 4.2e-10 39.3 0.1 7.5e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MULE PF10551.9 RJW59908.1 - 1.2e-06 28.9 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Zds_C PF08632.10 RJW59908.1 - 0.05 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term WD40 PF00400.32 RJW59909.1 - 7.6e-15 55.0 7.5 5.8e-06 26.9 0.5 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW59909.1 - 7e-11 42.3 0.1 6.6e-05 23.1 0.0 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SMAP PF15477.6 RJW59909.1 - 2.7e-06 28.2 0.0 9.7e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Small acidic protein family eIF2A PF08662.11 RJW59909.1 - 7.5e-05 22.7 0.0 0.34 10.8 0.1 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A BUD22 PF09073.10 RJW59909.1 - 0.6 9.4 7.0 0.88 8.8 7.0 1.2 1 0 0 1 1 1 0 BUD22 AAA PF00004.29 RJW59911.1 - 1.3e-42 145.4 0.1 5.5e-42 143.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RJW59911.1 - 1.7e-22 79.1 0.1 3.4e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 RJW59911.1 - 8.4e-11 41.5 0.4 2.1e-10 40.2 0.4 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RJW59911.1 - 2e-06 28.3 0.8 0.0004 20.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 RJW59911.1 - 5.9e-06 26.3 0.2 5e-05 23.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RJW59911.1 - 1.4e-05 24.9 0.0 4.1e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RJW59911.1 - 0.00021 21.6 0.6 0.025 14.8 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 RJW59911.1 - 0.0007 19.8 0.1 0.0056 16.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 RJW59911.1 - 0.0013 17.9 0.0 0.0025 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 RJW59911.1 - 0.003 18.1 0.0 0.0074 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RJW59911.1 - 0.0049 16.3 0.1 0.033 13.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 RJW59911.1 - 0.0079 15.7 0.1 0.027 13.9 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 RJW59911.1 - 0.011 15.9 0.3 0.045 13.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RJW59911.1 - 0.013 15.2 0.1 0.077 12.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RJW59911.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 RJW59911.1 - 0.034 13.5 0.1 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 RJW59911.1 - 0.053 13.1 0.6 0.34 10.5 0.2 2.2 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RJW59911.1 - 0.061 13.0 0.1 0.29 10.8 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 RJW59911.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 RJW59911.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 RJW59911.1 - 0.096 12.2 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 RJW59911.1 - 0.13 12.2 0.4 2 8.3 0.0 2.3 1 1 1 2 2 2 0 NACHT domain rve PF00665.26 RJW59912.1 - 9.8e-15 54.8 0.0 1.5e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RJW59912.1 - 0.00018 21.2 0.0 0.00048 19.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Tropomyosin PF00261.20 RJW59913.1 - 8.6e-07 28.6 8.3 1.3e-06 28.0 8.2 1.4 1 1 0 1 1 1 1 Tropomyosin Filament PF00038.21 RJW59913.1 - 2.9e-05 23.8 0.5 3.2e-05 23.7 0.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein HrpB7 PF09486.10 RJW59913.1 - 0.00094 19.6 2.3 0.0014 19.0 2.3 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) ADIP PF11559.8 RJW59913.1 - 0.00096 19.3 6.9 0.00096 19.3 6.9 1.5 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding ABC_tran_Xtn PF12848.7 RJW59913.1 - 0.0054 16.7 1.1 0.0085 16.1 1.1 1.3 1 0 0 1 1 1 1 ABC transporter ATG16 PF08614.11 RJW59913.1 - 0.0063 16.8 8.1 0.0088 16.3 8.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 RJW59913.1 - 0.0074 15.8 1.4 0.0078 15.7 1.4 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Streptin-Immun PF11083.8 RJW59913.1 - 0.0075 16.6 1.7 0.015 15.7 1.3 1.7 2 0 0 2 2 1 1 Lantibiotic streptin immunity protein CC2-LZ PF16516.5 RJW59913.1 - 0.018 15.4 3.6 0.031 14.6 3.6 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF16 PF01519.16 RJW59913.1 - 0.018 15.5 2.4 0.018 15.5 2.4 1.4 2 0 0 2 2 1 0 Protein of unknown function DUF16 Cep57_CLD_2 PF14197.6 RJW59913.1 - 0.022 14.8 6.8 0.23 11.6 0.8 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 KxDL PF10241.9 RJW59913.1 - 0.023 14.9 1.9 0.041 14.2 1.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein UPF0242 PF06785.11 RJW59913.1 - 0.025 14.7 1.4 0.034 14.2 1.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 RJW59913.1 - 0.044 14.0 8.9 0.071 13.3 8.9 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF745 PF05335.13 RJW59913.1 - 0.049 13.3 1.0 0.061 13.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 RJW59913.1 - 0.052 13.7 3.4 0.073 13.3 2.2 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 RJW59913.1 - 0.08 12.8 3.7 0.14 12.0 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BST2 PF16716.5 RJW59913.1 - 0.091 13.4 4.9 0.044 14.4 3.2 1.5 2 0 0 2 2 1 0 Bone marrow stromal antigen 2 OmpH PF03938.14 RJW59913.1 - 0.12 12.7 4.3 0.16 12.3 4.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DHR10 PF18595.1 RJW59913.1 - 0.13 12.3 11.3 0.13 12.3 9.1 2.0 2 1 0 2 2 1 0 Designed helical repeat protein 10 domain FliD_N PF02465.18 RJW59913.1 - 0.15 12.8 3.1 2 9.2 1.1 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FlaC_arch PF05377.11 RJW59913.1 - 0.16 12.4 5.4 1.6 9.2 0.2 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 RJW59913.1 - 0.19 11.8 4.0 0.24 11.5 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 RJW59913.1 - 0.23 10.7 0.6 0.31 10.2 0.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Tho2 PF11262.8 RJW59913.1 - 0.26 10.5 2.8 0.33 10.1 2.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 RJW59913.1 - 0.33 10.2 8.2 0.4 10.0 8.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GvpG PF05120.12 RJW59913.1 - 0.43 10.6 7.4 0.16 12.0 4.4 1.9 2 1 1 3 3 2 0 Gas vesicle protein G GrpE PF01025.19 RJW59913.1 - 0.47 10.1 5.1 0.65 9.6 5.1 1.2 1 0 0 1 1 1 0 GrpE Baculo_PEP_C PF04513.12 RJW59913.1 - 0.49 10.4 3.6 0.62 10.1 2.1 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 RJW59913.1 - 0.5 11.0 7.0 0.38 11.4 4.9 1.9 2 0 0 2 2 2 0 SlyX CLZ PF16526.5 RJW59913.1 - 0.65 10.4 8.3 0.29 11.5 2.3 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MerR-DNA-bind PF09278.11 RJW59913.1 - 1.1 9.9 7.2 10 6.7 1.0 2.4 1 1 1 2 2 2 0 MerR, DNA binding DUF4140 PF13600.6 RJW59913.1 - 2.2 8.8 8.7 0.48 10.9 2.1 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mto2_bdg PF12808.7 RJW59913.1 - 3 8.2 11.1 14 6.0 11.0 2.0 1 1 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HalX PF08663.10 RJW59913.1 - 6.9 7.1 12.2 3.7 7.9 6.3 2.6 2 1 1 3 3 3 0 HalX domain Rer1 PF03248.13 RJW59917.1 - 3e-53 180.1 6.1 3.5e-53 179.9 6.1 1.0 1 0 0 1 1 1 1 Rer1 family CD225 PF04505.12 RJW59918.1 - 2.1e-06 27.8 3.6 2.1e-06 27.8 3.6 1.7 1 1 1 2 2 2 1 Interferon-induced transmembrane protein TcdB_toxin_midN PF12256.8 RJW59919.1 - 0.0069 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/N-terminal region Dus PF01207.17 RJW59920.1 - 7.6e-58 196.0 0.0 1.1e-57 195.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ATG13 PF10033.9 RJW59922.1 - 0.021 14.5 0.1 0.061 13.0 0.1 1.6 1 1 0 1 1 1 0 Autophagy-related protein 13 BMP2K_C PF15282.6 RJW59923.1 - 0.023 14.6 3.5 0.029 14.2 3.5 1.1 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus TIP49 PF06068.13 RJW59924.1 - 6.6e-112 374.2 0.2 3.5e-102 342.2 0.4 2.1 2 0 0 2 2 2 2 TIP49 P-loop domain TIP49_C PF17856.1 RJW59924.1 - 1.1e-19 70.3 0.0 3.4e-19 68.7 0.0 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA_22 PF13401.6 RJW59924.1 - 0.0038 17.5 0.0 0.0094 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 RJW59924.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RJW59924.1 - 0.11 12.3 0.2 0.27 10.9 0.1 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_2 PF17863.1 RJW59924.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain 7TM_GPCR_Srw PF10324.9 RJW59925.1 - 2.1e-31 109.4 16.2 1.3e-30 106.8 16.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RJW59925.1 - 2.1e-08 33.8 14.9 1.9e-07 30.7 14.9 2.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CBP_BcsG PF11658.8 RJW59925.1 - 0.028 12.9 0.1 0.098 11.0 0.0 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG TraB PF01963.17 RJW59926.1 - 2e-24 86.9 0.6 6.6e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 TraB family LANC_like PF05147.13 RJW59926.1 - 0.064 11.8 0.1 0.095 11.3 0.1 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein RVT_1 PF00078.27 RJW59928.1 - 3.1e-46 157.7 0.2 7.6e-46 156.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCDC66 PF15236.6 RJW59928.1 - 2.8e-38 131.1 15.3 2.8e-38 131.1 15.3 2.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 66 NuA4 PF09340.10 RJW59929.1 - 0.22 11.4 1.5 0.81 9.6 1.5 2.0 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 DUF4177 PF13783.6 RJW59930.1 - 0.054 13.8 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) PIF1 PF05970.14 RJW59931.1 - 1.4e-47 162.6 0.0 3e-46 158.2 0.0 2.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 RJW59931.1 - 6.4e-14 52.1 0.0 3.4e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RJW59931.1 - 4e-07 30.5 0.0 1.2e-06 29.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW59931.1 - 1.1e-05 25.7 0.0 3.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RJW59931.1 - 0.00031 20.8 0.0 0.0016 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 RJW59931.1 - 0.0031 17.3 2.2 1.1 8.9 0.2 3.4 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 RJW59931.1 - 0.0052 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 RJW59931.1 - 0.008 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 RJW59931.1 - 0.012 15.2 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD_C_2 PF13538.6 RJW59931.1 - 0.04 13.8 0.3 0.23 11.3 0.3 2.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_24 PF13479.6 RJW59931.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RJW59931.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 RJW59931.1 - 0.13 10.1 0.1 8.2 4.2 0.1 2.1 2 0 0 2 2 2 0 Helicase PhoH PF02562.16 RJW59931.1 - 0.14 11.6 0.0 0.64 9.4 0.0 2.1 3 0 0 3 3 3 0 PhoH-like protein AAA_32 PF13654.6 RJW59931.1 - 0.14 10.9 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RJW59931.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 NTPase ATP-synt_C PF00137.21 RJW59932.1 - 0.14 12.5 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 ATP synthase subunit C DUF4659 PF15558.6 RJW59933.1 - 1.7e-06 27.2 55.3 1.7e-06 27.2 55.3 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4659) DUF1943 PF09172.11 RJW59933.1 - 8.1 5.6 11.7 14 4.8 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Sec7 PF01369.20 RJW59934.1 - 5.5e-26 91.4 0.0 6.9e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Sec7 domain Fungal_trans_2 PF11951.8 RJW59935.1 - 0.029 13.2 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain PDZ_6 PF17820.1 RJW59937.1 - 1.2e-25 89.1 2.3 2.3e-12 46.6 0.1 3.5 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 RJW59937.1 - 1.3e-25 89.6 0.4 4.3e-09 36.6 0.0 3.4 3 0 0 3 3 3 3 PDZ domain ZU5 PF00791.20 RJW59937.1 - 8.7e-17 61.3 0.0 2.1e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain PDZ_2 PF13180.6 RJW59937.1 - 1e-07 32.1 0.3 0.0013 19.0 0.0 3.2 3 0 0 3 3 3 2 PDZ domain Guanylate_kin PF00625.21 RJW59937.1 - 0.0001 22.0 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase RNA_pol_L PF01193.24 RJW59938.1 - 2.4e-20 71.7 0.0 1.2e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 RJW59938.1 - 4.8e-20 72.0 0.0 8.1e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L_2 PF13656.6 RJW59938.1 - 1.3e-15 56.9 0.0 1.7e-14 53.3 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb3/Rpb11 dimerisation domain BTB_2 PF02214.22 RJW59940.1 - 7.5e-16 58.3 0.0 5.4e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain BTB_3 PF16017.5 RJW59940.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain FGGY_N PF00370.21 RJW59941.1 - 3.4e-38 131.6 0.0 7.5e-37 127.2 0.0 2.5 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 RJW59941.1 - 4.2e-24 85.4 0.0 8.3e-24 84.4 0.0 1.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 RJW59941.1 - 0.095 12.2 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family TSNAXIP1_N PF15739.5 RJW59942.1 - 1.4e-26 93.0 0.3 1.4e-26 93.0 0.3 3.5 2 1 1 3 3 3 1 Translin-associated factor X-interacting N-terminus DUF4407 PF14362.6 RJW59942.1 - 0.056 12.8 6.9 0.099 12.0 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tho2 PF11262.8 RJW59942.1 - 0.17 11.0 13.1 0.05 12.8 4.1 2.4 1 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF948 PF06103.11 RJW59942.1 - 0.22 11.8 3.4 7.1 7.0 0.2 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sec5 PF15469.6 RJW59942.1 - 0.23 11.2 4.2 1.1 9.0 0.1 2.6 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF16 PF01519.16 RJW59942.1 - 0.29 11.6 12.2 0.45 11.0 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 ADIP PF11559.8 RJW59942.1 - 0.45 10.6 17.5 0.27 11.3 3.9 2.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2681 PF10883.8 RJW59942.1 - 0.53 10.7 7.6 0.85 10.1 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Spc7 PF08317.11 RJW59942.1 - 0.66 8.8 22.8 2.6 6.8 4.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Prominin PF05478.11 RJW59942.1 - 1.9 6.3 7.5 0.18 9.7 1.5 1.8 1 1 1 2 2 2 0 Prominin Nup54 PF13874.6 RJW59942.1 - 2.1 8.5 13.4 0.83 9.8 0.8 2.7 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 NPV_P10 PF05531.12 RJW59942.1 - 2.1 8.9 5.9 2.3 8.8 1.2 3.1 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Cep57_MT_bd PF06657.13 RJW59942.1 - 3.1 8.3 16.5 0.049 14.1 3.2 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 RJW59942.1 - 3.5 8.3 12.5 2.7 8.7 2.8 3.1 1 1 1 2 2 2 0 Initiation control protein YabA Nup88 PF10168.9 RJW59942.1 - 3.7 5.3 14.3 5.4 4.7 14.3 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF4085 PF13315.6 RJW59942.1 - 3.7 7.1 8.0 0.46 10.1 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Rootletin PF15035.6 RJW59942.1 - 5.4 7.0 30.2 0.17 11.9 3.2 4.4 2 1 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion Cep57_CLD_2 PF14197.6 RJW59942.1 - 7.6 6.7 21.4 0.62 10.2 0.2 4.4 5 1 0 5 5 5 0 Centrosome localisation domain of PPC89 CAP PF00188.26 RJW59943.1 - 1.1e-20 74.7 0.0 1.4e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family T-box PF00907.22 RJW59944.1 - 1.8e-69 233.7 0.1 2.9e-69 233.0 0.1 1.3 1 0 0 1 1 1 1 T-box MSP PF01716.18 RJW59944.1 - 0.076 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide RVT_1 PF00078.27 RJW59945.1 - 1.3e-05 24.8 0.0 4.7e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIT_CC PF16559.5 RJW59945.1 - 0.084 12.8 0.6 0.17 11.7 0.6 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 RJW59945.1 - 0.33 11.4 9.7 1.2 9.6 7.5 2.7 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Tropomyosin_1 PF12718.7 RJW59945.1 - 1.3 9.2 11.5 13 5.9 11.5 2.0 1 1 0 1 1 1 0 Tropomyosin like KLRAQ PF10205.9 RJW59945.1 - 2 8.7 6.3 4.3 7.6 1.3 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Cortex-I_coil PF09304.10 RJW59945.1 - 3.8 7.8 9.9 0.94 9.7 6.1 2.0 2 1 0 2 2 2 0 Cortexillin I, coiled coil Spc7 PF08317.11 RJW59945.1 - 4.1 6.2 9.5 6 5.7 9.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Ras PF00071.22 RJW59950.1 - 6.7e-58 194.9 0.1 8.4e-58 194.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW59950.1 - 1.1e-33 116.0 0.0 1.8e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW59950.1 - 3.8e-10 39.5 0.1 5.3e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW59950.1 - 0.00019 21.5 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RJW59950.1 - 0.0045 16.9 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 RJW59950.1 - 0.0093 15.5 0.1 0.03 13.9 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 RJW59950.1 - 0.012 16.0 0.1 0.031 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 RJW59950.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region KAP_NTPase PF07693.14 RJW59950.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 RJW59950.1 - 0.019 15.3 0.1 0.13 12.5 0.1 2.4 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 RJW59950.1 - 0.029 13.8 0.1 0.063 12.7 0.0 1.6 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 RJW59950.1 - 0.031 13.8 0.0 0.093 12.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 RJW59950.1 - 0.032 14.4 0.1 0.23 11.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RJW59950.1 - 0.05 14.1 0.0 0.089 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MCM PF00493.23 RJW59950.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 RJW59950.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Ras PF00071.22 RJW59951.1 - 1.2e-59 200.5 0.3 1.5e-59 200.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW59951.1 - 2.4e-34 118.1 0.1 3.6e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW59951.1 - 6.1e-13 48.6 0.0 8.2e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW59951.1 - 6.6e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RJW59951.1 - 0.00039 20.4 0.6 0.0021 18.0 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 RJW59951.1 - 0.00059 19.3 0.1 0.0011 18.3 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RJW59951.1 - 0.0014 18.2 0.0 0.0084 15.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 RJW59951.1 - 0.0074 15.8 0.3 0.013 15.0 0.3 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 RJW59951.1 - 0.0093 16.4 0.1 0.015 15.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RJW59951.1 - 0.011 16.0 0.1 0.029 14.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 RJW59951.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain SRPRB PF09439.10 RJW59951.1 - 0.033 13.6 0.1 0.1 12.0 0.0 1.8 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit MCM PF00493.23 RJW59951.1 - 0.036 13.1 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 RJW59951.1 - 0.041 14.4 0.0 0.061 13.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 RJW59951.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 RJW59951.1 - 0.073 12.2 0.1 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FeoB_N PF02421.18 RJW59951.1 - 0.088 12.3 0.1 0.28 10.7 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 RJW59951.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 RJW59951.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Guanylate_cyc PF00211.20 RJW59952.1 - 3.8e-31 108.1 0.0 3e-21 75.9 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Orthopox_C10L PF07020.11 RJW59952.1 - 0.15 12.8 4.2 16 6.3 0.3 3.0 2 0 0 2 2 2 0 Orthopoxvirus C10L protein Sec39 PF08314.11 RJW59954.1 - 0.039 12.4 0.0 0.09 11.2 0.0 1.5 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Pkinase PF00069.25 RJW59956.1 - 8.9e-48 162.9 0.0 1.6e-47 162.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW59956.1 - 2.9e-21 75.9 0.1 6.5e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C2H2 PF00096.26 RJW59957.1 - 0.0035 17.7 13.3 0.064 13.7 1.0 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW59957.1 - 0.013 16.3 14.4 0.047 14.6 1.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW59957.1 - 0.04 14.2 0.9 0.43 10.9 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_6 PF14599.6 RJW59957.1 - 0.049 13.6 0.2 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-ribbon zf_C2H2_ZHX PF18387.1 RJW59957.1 - 0.47 10.1 5.7 0.33 10.6 0.3 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain RVT_1 PF00078.27 RJW59959.1 - 1.2e-21 77.3 0.0 1.2e-13 51.1 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 RJW59962.1 - 1.8e-43 148.9 0.0 2.9e-42 144.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW59962.1 - 1.5e-18 67.0 0.0 5.7e-18 65.1 0.0 1.6 1 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW59962.1 - 0.0035 16.7 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW59962.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RJW59962.1 - 0.041 13.2 0.1 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LLC1 PF14945.6 RJW59964.1 - 0.061 13.9 1.2 21 5.7 0.2 3.2 2 1 0 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Ank_2 PF12796.7 RJW59965.1 - 3.4e-38 130.1 1.2 1.2e-14 54.6 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW59965.1 - 8.4e-27 93.2 3.8 3.3e-07 30.7 0.2 6.3 3 1 3 6 6 6 5 Ankyrin repeats (many copies) MULE PF10551.9 RJW59965.1 - 3.9e-22 78.5 0.0 1e-21 77.1 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Ank PF00023.30 RJW59965.1 - 1.8e-20 72.4 4.2 0.03 14.8 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 RJW59965.1 - 7.2e-18 62.8 8.8 0.033 14.7 0.0 9.7 9 1 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 RJW59965.1 - 2.6e-14 53.1 4.1 0.00017 21.8 0.1 5.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) FAR1 PF03101.15 RJW59965.1 - 0.0026 18.4 0.3 0.0098 16.6 0.3 2.1 1 0 0 1 1 1 1 FAR1 DNA-binding domain zf-C3H2C3 PF17122.5 RJW59965.1 - 0.0073 16.3 2.2 0.027 14.5 0.4 3.0 2 0 0 2 2 2 1 Zinc-finger OTT_1508_deam PF14441.6 RJW59965.1 - 0.23 11.5 3.9 0.4 10.7 0.3 3.3 3 0 0 3 3 3 0 OTT_1508-like deaminase ELO PF01151.18 RJW59966.1 - 6.8e-63 212.5 21.1 8.2e-63 212.2 21.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family 7TM_GPCR_Srw PF10324.9 RJW59967.1 - 4.4e-22 78.8 22.6 5.3e-19 68.7 9.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RJW59967.1 - 3.5e-15 56.1 16.6 7.2e-15 55.0 16.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW59967.1 - 7.2e-05 22.5 16.4 7.2e-05 22.5 16.4 3.0 3 1 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx UPF0542 PF15086.6 RJW59967.1 - 0.011 15.6 0.7 0.03 14.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF2973 PF11189.8 RJW59967.1 - 0.15 12.2 0.3 0.93 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) CH PF00307.31 RJW59971.1 - 2.5e-12 46.9 0.0 4.2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 RJW59971.1 - 0.04 14.0 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 CH-like domain in sperm protein Forkhead PF00250.18 RJW59972.1 - 7.8e-26 90.2 0.4 1.8e-25 89.0 0.4 1.6 1 0 0 1 1 1 1 Forkhead domain FOXP-CC PF16159.5 RJW59972.1 - 1e-18 67.7 0.2 2.5e-18 66.4 0.2 1.7 1 0 0 1 1 1 1 FOXP coiled-coil domain Coronavirus_5 PF05528.11 RJW59972.1 - 0.09 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Coronavirus gene 5 protein COG7 PF10191.9 RJW59973.1 - 4.6e-92 309.6 0.0 3.9e-77 260.2 0.0 3.0 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) Methyltransf_25 PF13649.6 RJW59973.1 - 1.6e-10 41.6 0.0 5.8e-10 39.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RJW59973.1 - 6.3e-10 38.9 0.2 1.5e-09 37.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 RJW59973.1 - 4.9e-08 33.5 0.1 2.2e-07 31.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW59973.1 - 5.9e-08 32.6 0.0 3.9e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain COG5 PF10392.9 RJW59973.1 - 3.6e-05 23.9 0.4 7.9e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Methyltransf_23 PF13489.6 RJW59973.1 - 0.00015 21.7 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 RJW59973.1 - 0.00016 21.7 0.1 0.00051 20.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RJW59973.1 - 0.00054 19.5 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 RJW59973.1 - 0.0012 18.5 0.1 0.03 14.0 0.0 2.7 3 0 0 3 3 3 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 RJW59973.1 - 0.0016 17.5 0.0 0.0034 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 RJW59973.1 - 0.0068 17.1 0.0 0.017 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RJW59973.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase IFT20 PF14931.6 RJW59973.1 - 0.15 12.2 1.3 0.34 11.1 1.3 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 PCMT PF01135.19 RJW59973.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HIP1_clath_bdg PF16515.5 RJW59973.1 - 0.8 10.3 7.8 0.053 14.1 2.4 1.8 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 RJW59973.1 - 2.8 6.8 4.6 4.3 6.1 2.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein NHL PF01436.21 RJW59974.1 - 2.8e-21 74.4 3.5 6.9e-06 25.8 0.1 3.9 3 0 0 3 3 3 3 NHL repeat SGL PF08450.12 RJW59974.1 - 0.00094 18.8 0.0 0.0045 16.6 0.0 2.0 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 RJW59974.1 - 0.2 10.9 0.0 0.46 9.7 0.0 1.5 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PSS PF03034.15 RJW59975.1 - 5.4e-101 337.9 15.8 9e-101 337.2 15.8 1.4 1 0 0 1 1 1 1 Phosphatidyl serine synthase Aminotran_5 PF00266.19 RJW59976.1 - 5.4e-45 153.9 0.0 6.2e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V FYVE_2 PF02318.16 RJW59977.1 - 6e-20 71.6 9.0 6e-20 71.6 9.0 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Ig_3 PF13927.6 RJW59977.1 - 4.2e-09 36.9 0.8 0.0003 21.3 0.0 4.6 2 1 1 3 3 3 2 Immunoglobulin domain I-set PF07679.16 RJW59977.1 - 3.8e-08 33.3 0.0 0.099 12.7 0.0 4.1 3 1 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 RJW59977.1 - 1.6e-07 31.4 0.1 0.034 14.3 0.1 3.6 2 1 0 2 2 2 2 Immunoglobulin domain FYVE PF01363.21 RJW59977.1 - 4.9e-06 26.6 5.7 1.3e-05 25.2 5.7 1.8 1 0 0 1 1 1 1 FYVE zinc finger Ig_2 PF13895.6 RJW59977.1 - 2.4e-05 24.6 0.5 0.025 14.9 0.1 4.3 2 2 1 3 3 3 1 Immunoglobulin domain Ig_6 PF18452.1 RJW59977.1 - 0.0052 16.3 0.0 5.1 6.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RJW59977.1 - 0.0071 16.5 0.0 2 8.6 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin V-set domain DNA_RNApol_7kD PF03604.13 RJW59977.1 - 0.16 11.7 3.5 0.16 11.7 1.7 2.0 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit C1_1 PF00130.22 RJW59977.1 - 0.41 10.6 9.2 0.075 12.9 3.5 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_10 PF16685.5 RJW59977.1 - 0.8 9.9 6.2 2.4 8.3 6.2 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 Efg1 PF10153.9 RJW59977.1 - 2 8.8 10.2 0.063 13.6 2.1 2.6 2 1 0 2 2 2 0 rRNA-processing protein Efg1 Otopetrin PF03189.13 RJW59978.1 - 3.8e-117 391.8 17.7 5.8e-117 391.2 17.7 1.3 1 0 0 1 1 1 1 Otopetrin Fez1 PF06818.15 RJW59979.1 - 5.7 7.4 79.8 0.18 12.2 14.5 4.3 1 1 3 4 4 4 0 Fez1 Pkinase PF00069.25 RJW59980.1 - 3.4e-42 144.6 0.0 1.7e-29 103.0 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW59980.1 - 1.6e-21 76.8 0.0 1.1e-11 44.6 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RJW59980.1 - 0.0086 15.4 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RJW59980.1 - 0.018 15.0 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cohesin_load PF10345.9 RJW59983.1 - 1.9e-69 234.7 2.2 2.3e-69 234.4 2.2 1.1 1 0 0 1 1 1 1 Cohesin loading factor TPR_MalT PF17874.1 RJW59983.1 - 2.2e-06 27.3 8.2 0.0011 18.4 0.0 4.2 2 1 2 4 4 4 2 MalT-like TPR region TPR_14 PF13428.6 RJW59983.1 - 5.3e-05 23.7 0.5 28 5.9 0.2 6.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 RJW59983.1 - 0.0043 17.2 0.6 20 5.7 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW59983.1 - 0.0084 16.2 0.0 17 5.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 RJW59983.1 - 0.14 11.6 0.4 0.53 9.7 0.1 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_4 PF07721.14 RJW59983.1 - 4.3 8.3 8.2 18 6.3 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Cyclin_C_2 PF16899.5 RJW59985.1 - 5.2e-10 39.6 0.0 2.1e-08 34.5 0.0 2.6 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 RJW59985.1 - 6.9e-08 32.3 0.0 1.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain YceD PF02620.17 RJW59985.1 - 0.016 15.3 0.4 0.047 13.8 0.4 1.7 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD RVT_1 PF00078.27 RJW59987.1 - 3.1e-05 23.6 0.0 8.5e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Endosulfine PF04667.17 RJW59990.1 - 2.2e-05 24.5 0.3 3e-05 24.1 0.3 1.5 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Pribosyl_synth PF14572.6 RJW59991.1 - 2.5e-85 285.1 0.1 3.8e-85 284.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 RJW59991.1 - 1.4e-35 121.7 0.2 3.2e-35 120.6 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 RJW59991.1 - 3.9e-08 33.0 0.0 7.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FrhB_FdhB_N PF04422.13 RJW59991.1 - 0.1 12.8 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term RRM_1 PF00076.22 RJW59992.1 - 9.6e-10 38.2 0.0 2.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ig_3 PF13927.6 RJW59993.1 - 1.7e-17 63.7 1.9 3e-11 43.8 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RJW59993.1 - 2.8e-16 59.6 0.4 1.1e-10 41.7 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RJW59993.1 - 1.3e-15 57.2 0.0 3.5e-08 33.4 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 RJW59993.1 - 1.3e-14 54.1 2.0 2.3e-08 34.1 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RJW59993.1 - 9.4e-08 32.2 4.2 0.068 13.3 0.2 3.7 2 2 1 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 RJW59993.1 - 0.00017 21.1 0.0 0.72 9.5 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 RJW59993.1 - 0.016 15.4 0.0 5 7.5 0.0 2.6 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RJW59993.1 - 0.028 14.8 0.0 5.1 7.6 0.0 2.9 3 1 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 RJW59993.1 - 0.052 13.6 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain ABC_membrane PF00664.23 RJW59994.1 - 2.5e-97 325.8 34.5 9.1e-51 173.1 11.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RJW59994.1 - 5.5e-66 221.3 0.0 1.4e-33 116.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RJW59994.1 - 1e-17 64.4 0.0 2.5e-08 33.7 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RJW59994.1 - 5.9e-12 46.3 0.7 7.2e-05 23.2 0.0 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 RJW59994.1 - 2.8e-09 37.4 1.4 0.012 15.9 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RJW59994.1 - 5.8e-08 32.4 0.1 0.008 15.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RJW59994.1 - 1.1e-07 32.0 0.0 0.22 11.3 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RJW59994.1 - 1.2e-07 31.8 0.0 0.023 14.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 RJW59994.1 - 3e-07 29.9 0.0 0.013 14.7 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 RJW59994.1 - 7.9e-07 29.0 0.2 0.077 12.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 RJW59994.1 - 1.2e-06 27.6 0.1 0.031 13.1 0.1 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 RJW59994.1 - 1.9e-06 27.3 0.8 0.17 11.1 0.0 3.6 3 0 0 3 3 3 1 Zeta toxin AAA_7 PF12775.7 RJW59994.1 - 2e-06 27.4 0.0 0.048 13.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 RJW59994.1 - 5.3e-06 26.4 0.0 0.016 14.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 RJW59994.1 - 1.8e-05 24.8 0.1 0.38 10.7 0.0 3.3 2 1 0 3 3 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 RJW59994.1 - 3.3e-05 23.9 0.2 0.35 10.8 0.0 3.4 3 0 0 3 3 3 2 NACHT domain SbcCD_C PF13558.6 RJW59994.1 - 4.8e-05 23.5 5.6 0.061 13.6 0.5 4.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.29 RJW59994.1 - 5.6e-05 23.6 1.5 3.5 8.1 0.1 4.5 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RJW59994.1 - 0.00024 20.8 0.5 7 6.3 0.0 3.7 4 0 0 4 4 3 0 Sigma-54 interaction domain Rad17 PF03215.15 RJW59994.1 - 0.00031 20.7 0.2 0.35 10.8 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain NB-ARC PF00931.22 RJW59994.1 - 0.00034 19.9 0.1 1.1 8.3 0.0 3.1 3 0 0 3 3 3 2 NB-ARC domain AAA_18 PF13238.6 RJW59994.1 - 0.00037 21.0 0.0 0.36 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 RJW59994.1 - 0.00042 20.1 0.0 0.93 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RJW59994.1 - 0.00042 20.9 0.0 0.58 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RJW59994.1 - 0.00067 19.4 1.7 8.3 6.1 0.0 4.3 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 RJW59994.1 - 0.00069 19.2 0.1 1.4 8.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 RJW59994.1 - 0.0007 19.6 0.0 0.26 11.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 RJW59994.1 - 0.0014 17.9 0.0 0.63 9.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 RJW59994.1 - 0.0015 18.7 0.5 0.79 9.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain PRK PF00485.18 RJW59994.1 - 0.0034 17.1 0.0 0.91 9.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 RJW59994.1 - 0.0042 17.2 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 RJW59994.1 - 0.0043 17.4 0.0 5.5 7.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.25 RJW59994.1 - 0.0044 16.7 0.3 1.8 8.2 0.0 3.1 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 RJW59994.1 - 0.0053 16.8 0.1 4.9 7.2 0.0 3.3 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 RJW59994.1 - 0.006 16.3 0.5 0.69 9.7 0.1 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 RJW59994.1 - 0.0084 16.3 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 RJW59994.1 - 0.011 15.8 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 RJW59994.1 - 0.012 15.8 0.0 8.3 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 RJW59994.1 - 0.018 14.9 0.0 5.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 RJW59994.1 - 0.018 15.4 1.9 6.2 7.3 0.0 3.7 4 1 1 5 5 2 0 AAA domain Cytidylate_kin PF02224.18 RJW59994.1 - 0.021 14.6 0.0 0.77 9.5 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 RJW59994.1 - 0.023 14.6 0.0 14 5.5 0.0 3.3 3 0 0 3 3 3 0 NTPase TniB PF05621.11 RJW59994.1 - 0.072 12.5 0.0 18 4.7 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein ATP_bind_1 PF03029.17 RJW59994.1 - 0.075 12.8 0.1 3.9 7.2 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 RJW59994.1 - 0.078 12.3 0.1 7.9 5.7 0.0 2.8 2 1 0 3 3 3 0 FtsK/SpoIIIE family FumaraseC_C PF10415.9 RJW59994.1 - 0.14 12.6 1.2 2.1 8.8 0.0 3.2 4 0 0 4 4 2 0 Fumarase C C-terminus G_glu_transpept PF01019.21 RJW59997.1 - 2.3e-52 178.4 0.0 8e-52 176.6 0.0 1.7 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Ig_3 PF13927.6 RJW59999.1 - 0.022 15.4 0.0 0.54 10.9 0.0 2.2 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 RJW59999.1 - 0.028 14.6 0.1 5.8 7.1 0.0 3.0 1 1 0 2 2 2 0 Immunoglobulin V-set domain Cystatin PF00031.21 RJW60000.1 - 2.9e-06 27.4 0.3 5.8e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 RJW60000.1 - 0.09 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor PigN PF04987.14 RJW60001.1 - 5.1e-94 315.7 32.1 5.1e-94 315.7 32.1 1.4 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 RJW60001.1 - 1.6e-12 47.7 1.3 6e-12 45.8 1.3 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 RJW60001.1 - 0.00018 20.9 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 RJW60001.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 2 0 0 2 2 2 0 Sulfatase MazG_C PF18722.1 RJW60001.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 MazG C-terminal domain ATG16 PF08614.11 RJW60002.1 - 0.0013 19.0 5.8 0.0013 19.0 5.8 8.7 4 2 3 8 8 8 2 Autophagy protein 16 (ATG16) HTH_26 PF13443.6 RJW60002.1 - 0.069 13.6 1.5 0.25 11.8 0.1 2.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain DUF2935 PF11155.8 RJW60002.1 - 1.1 9.6 12.0 0.81 10.0 0.3 4.5 4 2 0 4 4 4 0 Domain of unknown function (DUF2935) Proteasome PF00227.26 RJW60004.1 - 7.9e-48 162.5 0.0 9.6e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RJW60004.1 - 3.3e-13 49.1 0.0 5.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LigB PF02900.18 RJW60004.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Pkinase PF00069.25 RJW60005.1 - 3.4e-70 236.4 0.0 4.5e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60005.1 - 6.5e-37 127.2 0.0 8.6e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW60005.1 - 5.2e-07 29.3 0.0 1.3e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 RJW60005.1 - 1.5e-06 28.8 1.5 3.1e-06 27.8 0.2 2.3 2 1 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 RJW60005.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RJW60005.1 - 0.14 10.9 0.1 0.44 9.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase BSP_II PF05432.11 RJW60005.1 - 0.53 9.9 9.8 0.99 9.0 9.8 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) WD40 PF00400.32 RJW60010.1 - 2.2e-35 120.1 17.7 3.9e-07 30.7 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 RJW60010.1 - 6.4e-07 29.2 0.2 2.1e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like WD40_like PF17005.5 RJW60010.1 - 1.7e-05 24.3 0.1 0.99 8.7 0.0 3.2 1 1 1 3 3 3 3 WD40-like domain ANAPC4_WD40 PF12894.7 RJW60010.1 - 5e-05 23.5 0.2 11 6.3 0.0 4.7 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 RJW60010.1 - 0.00019 21.2 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.6 RJW60010.1 - 0.01 15.9 0.0 3.9 7.6 0.0 3.8 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 RJW60010.1 - 0.21 10.2 4.3 21 3.6 0.0 4.4 2 2 3 5 5 5 0 Nucleoporin Nup120/160 DUF5542 PF17696.1 RJW60011.1 - 0.2 11.8 0.4 0.51 10.5 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Mto2_bdg PF12808.7 RJW60013.1 - 0.089 13.1 0.4 0.18 12.1 0.4 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Pkinase PF00069.25 RJW60015.1 - 1.2e-69 234.6 0.0 1.7e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60015.1 - 4.4e-37 127.8 0.0 6.7e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RJW60015.1 - 2.4e-08 33.6 0.1 4e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RJW60015.1 - 8.3e-08 31.9 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW60015.1 - 4.5e-05 22.6 0.1 4.5e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain KA1 PF02149.19 RJW60015.1 - 8.1e-05 22.3 0.2 0.00099 18.9 0.0 2.4 2 0 0 2 2 2 1 Kinase associated domain 1 APH PF01636.23 RJW60015.1 - 0.00013 21.9 0.3 0.0026 17.7 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RJW60015.1 - 0.0002 21.0 0.1 0.00042 20.0 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.11 RJW60015.1 - 0.022 14.4 0.5 0.037 13.6 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) EAR PF07897.11 RJW60016.1 - 1 9.0 2.3 0.7 9.6 0.1 1.8 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression Ldh_1_C PF02866.18 RJW60017.1 - 2.3e-05 24.4 0.0 0.00016 21.7 0.0 2.1 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 RJW60017.1 - 0.04 14.0 0.0 0.55 10.3 0.0 2.2 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain tRNA-synt_2c PF01411.19 RJW60018.1 - 6.6e-209 695.0 0.0 9.5e-209 694.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 RJW60018.1 - 1.6e-16 60.1 0.3 4.1e-16 58.8 0.3 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 RJW60018.1 - 4.4e-13 49.8 0.3 1.1e-12 48.6 0.3 1.7 1 0 0 1 1 1 1 DHHA1 domain MH2 PF03166.14 RJW60019.1 - 2.2e-64 217.1 0.0 2.9e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 RJW60019.1 - 2.9e-39 133.4 0.6 4.8e-39 132.7 0.6 1.4 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 RJW60019.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 zf-HC5HC2H_2 PF13832.6 RJW60020.1 - 2.3e-31 108.2 3.4 2.3e-31 108.2 3.4 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RJW60020.1 - 2.1e-23 82.4 0.3 2.1e-23 82.4 0.3 3.3 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 RJW60020.1 - 1.9e-13 49.7 11.8 1.3e-12 47.1 4.6 2.9 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 RJW60020.1 - 9.7e-11 41.4 23.3 6e-10 38.9 6.9 3.3 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 RJW60020.1 - 0.0073 16.7 1.6 0.024 15.0 0.0 2.4 3 0 0 3 3 3 1 Enhancer of polycomb-like zf-PHD-like PF15446.6 RJW60020.1 - 0.017 14.8 1.8 0.017 14.8 1.8 2.4 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Csc2 PF18320.1 RJW60020.1 - 0.15 11.0 0.1 0.27 10.1 0.1 1.3 1 0 0 1 1 1 0 Csc2 Crispr FANCL_C PF11793.8 RJW60020.1 - 9 6.6 13.7 1.9 8.7 1.8 2.7 2 0 0 2 2 2 0 FANCL C-terminal domain zf-UDP PF14569.6 RJW60020.1 - 9.5 6.4 12.1 0.28 11.3 5.1 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger UPF0506 PF11703.8 RJW60022.1 - 2e-21 76.1 20.4 2.4e-21 75.9 20.4 1.1 1 0 0 1 1 1 1 UPF0506 Dickkopf_N PF04706.12 RJW60022.1 - 0.53 10.8 20.7 3.7 8.1 18.0 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Conotoxin_I2 PF17557.2 RJW60022.1 - 6.8 6.9 20.9 1.5 9.0 9.8 2.3 2 0 0 2 2 2 0 I2-superfamily conotoxins UPF0506 PF11703.8 RJW60024.1 - 4.7e-21 74.9 21.3 5.6e-21 74.7 21.3 1.1 1 0 0 1 1 1 1 UPF0506 Toxin_12 PF07740.12 RJW60024.1 - 0.39 11.5 21.4 0.9 10.3 5.8 2.6 2 1 0 2 2 2 0 Ion channel inhibitory toxin Conotoxin PF02950.17 RJW60024.1 - 1.9 9.5 21.6 2.2 9.4 5.2 2.1 1 1 1 2 2 2 0 Conotoxin Dickkopf_N PF04706.12 RJW60024.1 - 5.3 7.6 22.3 18 5.9 19.0 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region DUF4139 PF13598.6 RJW60025.1 - 4e-44 150.8 0.0 8e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 RJW60025.1 - 0.093 13.2 2.3 5.7 7.4 0.6 3.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.19 RJW60025.1 - 3.1 5.6 10.2 3.7 5.3 9.1 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CLZ PF16526.5 RJW60025.1 - 4 7.9 6.9 4.8 7.6 0.8 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels VIT PF08487.10 RJW60026.1 - 5.3e-29 100.7 2.5 1.1e-28 99.7 2.5 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 RJW60026.1 - 6.9e-20 71.6 0.0 1.5e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 RJW60026.1 - 8.1e-12 44.9 0.2 1.8e-11 43.8 0.2 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 RJW60026.1 - 9.1e-11 42.4 0.0 2.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RJW60026.1 - 3.9e-10 40.3 0.0 7.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain LRR_8 PF13855.6 RJW60027.1 - 4.9e-21 74.2 18.7 5.3e-09 35.7 5.4 4.3 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RJW60027.1 - 5.7e-16 58.4 41.0 2.6e-07 30.9 1.3 5.3 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW60027.1 - 3.1e-08 33.0 19.5 2.7 8.9 0.2 8.5 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 RJW60027.1 - 8.3e-05 22.3 23.5 6.8 7.0 0.1 7.4 7 0 0 7 7 7 4 Leucine Rich repeat LRR_9 PF14580.6 RJW60027.1 - 0.029 13.9 8.7 0.53 9.8 1.3 2.6 1 1 0 2 2 2 0 Leucine-rich repeat COPI_C PF06957.11 RJW60028.1 - 9e-142 472.6 0.0 1.3e-141 472.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 RJW60028.1 - 6e-120 401.3 0.4 1.1e-119 400.4 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 RJW60028.1 - 1.5e-36 123.7 21.8 5.7e-06 27.0 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW60028.1 - 0.00028 21.1 3.2 2.2 8.6 0.0 5.0 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_16 PF13432.6 RJW60028.1 - 0.0079 16.8 6.2 2.6 8.8 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW60028.1 - 0.059 14.2 2.4 3.5 8.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 RJW60028.1 - 0.27 11.5 1.4 12 6.3 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Nup160 PF11715.8 RJW60028.1 - 0.58 8.7 8.0 3.2 6.3 1.0 3.3 3 1 0 3 3 3 0 Nucleoporin Nup120/160 AAA_6 PF12774.7 RJW60029.1 - 4.1e-157 522.3 0.0 2.4e-155 516.5 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW60029.1 - 1.7e-115 386.4 21.3 3.4e-105 352.4 2.9 4.4 5 0 0 5 5 5 2 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RJW60029.1 - 2.9e-97 325.1 0.1 7.9e-97 323.6 0.0 1.9 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RJW60029.1 - 1.6e-85 285.7 1.9 1.2e-83 279.6 1.3 2.9 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 RJW60029.1 - 3.3e-82 276.2 0.2 1.5e-81 274.0 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RJW60029.1 - 1.8e-74 249.2 1.2 6.3e-69 231.1 0.0 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RJW60029.1 - 1e-56 191.3 0.6 3.2e-56 189.7 0.1 2.2 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RJW60029.1 - 5e-51 173.7 7.5 6.3e-50 170.1 9.2 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RJW60029.1 - 8.6e-43 145.2 0.0 5.3e-42 142.7 0.0 2.5 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RJW60029.1 - 4.2e-26 91.6 0.2 4.3e-06 26.8 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RJW60029.1 - 1.3e-18 67.0 0.1 9.7e-18 64.2 0.1 2.7 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RJW60029.1 - 4.4e-16 59.2 0.0 2.1e-15 56.9 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 RJW60029.1 - 1.6e-09 38.1 1.5 0.065 13.5 0.0 5.6 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 RJW60029.1 - 2e-08 34.7 0.8 1.6 9.2 0.2 5.8 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW60029.1 - 1.1e-07 32.5 4.3 0.32 11.4 0.0 6.2 5 2 0 5 5 5 2 AAA ATPase domain T2SSE PF00437.20 RJW60029.1 - 0.0003 19.9 0.2 0.53 9.3 0.0 3.1 3 0 0 3 3 2 2 Type II/IV secretion system protein AAA_18 PF13238.6 RJW60029.1 - 0.00081 19.9 0.0 0.39 11.3 0.0 4.4 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 RJW60029.1 - 0.013 15.4 0.9 5.2 6.9 0.2 4.3 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 RJW60029.1 - 0.018 14.7 0.1 11 5.7 0.1 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 RJW60029.1 - 0.021 15.2 0.2 48 4.4 0.0 4.0 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 RJW60029.1 - 0.031 14.0 1.7 11 5.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 RJW60029.1 - 0.061 13.1 0.2 4.4 7.1 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF956 PF06115.11 RJW60029.1 - 0.063 13.0 0.5 6 6.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF956) DUF3437 PF11919.8 RJW60029.1 - 0.11 12.4 0.2 0.5 10.3 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) RsgA_GTPase PF03193.16 RJW60029.1 - 0.12 12.3 0.0 0.95 9.3 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 RJW60029.1 - 0.46 10.6 7.1 24 5.0 0.1 4.7 5 0 0 5 5 4 0 AAA domain ABC_tran PF00005.27 RJW60029.1 - 0.92 10.0 3.3 7.3 7.1 0.0 3.9 4 0 0 4 4 4 0 ABC transporter Fungal_TACC PF12709.7 RJW60029.1 - 5.8 7.4 8.2 2.5 8.6 4.0 2.7 2 0 0 2 2 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins CDK2AP PF09806.9 RJW60030.1 - 5.1e-17 62.7 0.2 8.6e-17 62.0 0.0 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein Arm_2 PF04826.13 RJW60031.1 - 1.3e-09 37.9 0.2 2.2e-09 37.1 0.2 1.4 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.23 RJW60031.1 - 0.075 13.1 1.7 17 5.6 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat fn3 PF00041.21 RJW60032.1 - 7.3e-08 32.6 1.1 0.083 13.3 0.0 4.6 3 2 0 3 3 3 2 Fibronectin type III domain SIR2 PF02146.17 RJW60033.1 - 4.6e-19 69.0 0.1 2.4e-11 43.9 0.0 2.9 3 1 0 3 3 3 2 Sir2 family Pox_A3L PF05288.11 RJW60033.1 - 0.066 13.2 0.6 0.31 11.0 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A3L Protein QVR PF17064.5 RJW60034.1 - 0.0014 18.8 5.9 0.0027 17.9 5.9 1.5 1 1 0 1 1 1 1 Sleepless protein UPAR_LY6_2 PF16975.5 RJW60034.1 - 0.039 14.1 3.1 0.068 13.4 3.1 1.5 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 DUF5133 PF17196.4 RJW60034.1 - 0.1 12.8 0.6 0.16 12.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF5133) Cofilin_ADF PF00241.20 RJW60035.1 - 2.9e-13 49.7 0.1 3.3e-13 49.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2004 PF09406.10 RJW60035.1 - 0.013 15.9 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) Glyco_hydro_15 PF00723.21 RJW60036.1 - 9.2e-62 209.3 0.0 1.1e-61 209.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Dynein_light PF01221.18 RJW60037.1 - 6.2e-12 45.7 0.0 9.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 RJW60037.1 - 0.0004 20.8 3.1 0.00087 19.7 3.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW60037.1 - 0.014 15.2 7.4 0.17 11.9 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 RJW60037.1 - 0.019 14.8 2.8 0.48 10.3 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_4 PF12763.7 RJW60037.1 - 0.095 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HTH_31 PF13560.6 RJW60037.1 - 0.12 12.7 0.0 14 6.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain EF-hand_1 PF00036.32 RJW60037.1 - 0.15 11.7 7.1 0.23 11.1 0.1 2.8 3 0 0 3 3 3 0 EF hand zf-UBR PF02207.20 RJW60038.1 - 8.2e-11 41.9 13.0 8.2e-11 41.9 13.0 3.5 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 RJW60038.1 - 1.7e-06 27.8 4.2 1.7e-06 27.8 4.2 3.2 4 0 0 4 4 4 2 PHD-finger Dynein_light PF01221.18 RJW60039.1 - 1.2e-17 63.9 0.4 1.9e-17 63.3 0.4 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 RJW60039.1 - 7.7e-06 26.3 1.9 1.4e-05 25.5 0.9 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW60039.1 - 2.5e-05 23.5 0.2 0.0016 17.9 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RJW60039.1 - 0.0004 20.1 3.7 0.023 14.6 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RJW60039.1 - 0.0015 18.4 0.3 0.024 14.5 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair DUF1697 PF08002.11 RJW60039.1 - 0.14 12.6 0.0 0.52 10.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1697) Ground-like PF04155.18 RJW60039.1 - 0.14 12.8 0.1 0.33 11.6 0.1 1.7 1 0 0 1 1 1 0 Ground-like domain KH_1 PF00013.29 RJW60040.1 - 1.9e-14 53.2 0.3 5.5e-13 48.5 0.4 2.8 3 0 0 3 3 3 1 KH domain KH_2 PF07650.17 RJW60040.1 - 0.00049 19.9 0.3 0.00083 19.1 0.3 1.2 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 RJW60040.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 KH domain Rhomboid PF01694.22 RJW60041.1 - 3.9e-08 33.4 8.5 4.6e-08 33.2 8.5 1.1 1 0 0 1 1 1 1 Rhomboid family zf-C2H2 PF00096.26 RJW60042.1 - 5.3e-56 184.1 212.3 0.00012 22.3 1.9 25.8 25 0 0 25 25 25 22 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW60042.1 - 4.9e-48 157.6 209.9 2.8e-05 24.6 1.6 25.4 25 0 0 25 25 24 24 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW60042.1 - 1.8e-26 91.3 183.7 1.7e-05 25.0 2.4 26.8 28 1 0 28 28 26 13 Zinc-finger double domain zf-met PF12874.7 RJW60042.1 - 6.1e-13 48.7 121.6 0.0068 16.8 0.1 21.1 21 0 0 21 21 21 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW60042.1 - 6.1e-08 32.8 90.3 0.03 14.6 0.1 20.1 22 0 0 22 22 22 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RJW60042.1 - 0.0012 18.6 1.8 0.0012 18.6 1.8 17.0 19 0 0 19 19 18 4 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RJW60042.1 - 0.0026 17.7 0.5 0.0026 17.7 0.5 21.4 23 0 0 23 23 23 8 C2H2-type zinc finger Rad50_zn_hook PF04423.14 RJW60042.1 - 0.0049 16.7 27.2 0.57 10.1 0.1 7.5 7 1 1 8 8 8 2 Rad50 zinc hook motif zf_C2H2_ZHX PF18387.1 RJW60042.1 - 0.0055 16.3 0.3 0.0055 16.3 0.3 13.0 12 4 5 17 17 17 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_8 PF15909.5 RJW60042.1 - 0.0086 16.4 3.5 0.0086 16.4 3.5 12.7 8 5 5 13 13 13 4 C2H2-type zinc ribbon DUF4428 PF14471.6 RJW60042.1 - 0.055 13.4 0.2 0.055 13.4 0.2 7.2 8 0 0 8 8 7 0 Domain of unknown function (DUF4428) zf-C2H2_3rep PF18868.1 RJW60042.1 - 2.7 8.7 79.1 0.1 13.3 1.4 13.0 8 6 7 15 15 15 0 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 RJW60042.1 - 4.4 7.8 50.1 0.37 11.3 0.1 10.1 11 0 0 11 11 9 0 Autophagy receptor zinc finger-C2H2 domain TMEM154 PF15102.6 RJW60043.1 - 0.0021 18.0 0.3 0.0039 17.1 0.3 1.4 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 RJW60043.1 - 0.0086 16.4 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Orf78 (ac78) EphA2_TM PF14575.6 RJW60043.1 - 0.079 13.8 0.1 0.18 12.7 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MFS_2 PF13347.6 RJW60043.1 - 0.11 11.0 0.1 0.48 8.9 0.0 1.8 2 0 0 2 2 2 0 MFS/sugar transport protein CARD_2 PF16739.5 RJW60044.1 - 0.081 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Caspase recruitment domain Methyltr_RsmB-F PF01189.17 RJW60045.1 - 4.2e-72 242.0 0.0 6e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 RJW60045.1 - 1.3e-09 38.4 0.0 3.1e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 RJW60045.1 - 2e-05 24.8 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 RJW60045.1 - 8.4e-05 22.4 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Fibrillarin PF01269.17 RJW60045.1 - 0.0018 17.4 0.0 0.0045 16.1 0.0 1.6 2 0 0 2 2 2 1 Fibrillarin PCMT PF01135.19 RJW60045.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Surp PF01805.20 RJW60046.1 - 5.1e-13 48.8 6.7 9.5e-12 44.7 6.7 2.5 1 1 0 1 1 1 1 Surp module cwf21 PF08312.12 RJW60046.1 - 6.4e-11 42.2 8.6 1.9e-10 40.7 8.6 1.9 1 0 0 1 1 1 1 cwf21 domain RRM_1 PF00076.22 RJW60046.1 - 6.3e-09 35.5 0.0 1.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 RJW60046.1 - 0.00073 20.3 0.1 0.002 18.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 RJW60046.1 - 0.096 12.7 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Dynein_light PF01221.18 RJW60048.1 - 4.2e-08 33.4 0.0 6.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_1 PF00036.32 RJW60048.1 - 4.4e-07 29.0 0.0 0.013 15.0 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW60048.1 - 3.5e-06 27.4 0.0 1.1e-05 25.7 0.0 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW60048.1 - 3.4e-05 23.4 0.0 0.24 11.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 RJW60048.1 - 0.0009 19.5 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain GPCR_chapero_1 PF11904.8 RJW60049.1 - 5e-88 295.5 0.0 6.8e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 RJW60049.1 - 0.00032 21.2 0.0 0.0013 19.3 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW60049.1 - 0.00035 20.8 0.1 0.0025 18.1 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 RJW60049.1 - 0.00047 20.5 1.1 0.0021 18.4 0.1 2.6 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 RJW60049.1 - 0.0079 16.5 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW60049.1 - 0.038 14.6 0.0 0.16 12.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) UIM PF02809.20 RJW60049.1 - 7.4 6.7 19.7 0.059 13.3 1.1 3.6 4 0 0 4 4 4 0 Ubiquitin interaction motif Dynein_light PF01221.18 RJW60050.1 - 3.5e-09 36.9 0.0 5.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_M28 PF04389.17 RJW60051.1 - 4.3e-22 78.8 0.0 6.8e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 BMP2K_C PF15282.6 RJW60053.1 - 0.043 13.7 0.7 0.044 13.6 0.7 1.0 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus Actin PF00022.19 RJW60054.1 - 1.6e-16 59.9 0.0 1.9e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Actin PTPA PF03095.15 RJW60055.1 - 3.5e-109 364.9 0.0 4.1e-109 364.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF4784 PF16023.5 RJW60056.1 - 0.0096 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4784) DnaJ PF00226.31 RJW60058.1 - 4.4e-07 29.9 0.1 7.2e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain GRIP PF01465.20 RJW60061.1 - 5.1e-12 45.5 3.0 1.2e-11 44.4 3.0 1.7 1 0 0 1 1 1 1 GRIP domain ApoO PF09769.9 RJW60061.1 - 0.49 10.4 3.2 7.2 6.6 0.2 3.5 3 0 0 3 3 3 0 Apolipoprotein O LRR_6 PF13516.6 RJW60062.1 - 2.2e-17 61.6 10.5 0.011 15.7 0.2 8.0 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 RJW60062.1 - 9.4e-08 32.2 9.0 0.019 15.3 0.3 5.3 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW60062.1 - 0.00012 22.1 9.3 35 5.5 0.0 7.5 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 RJW60062.1 - 0.001 18.8 12.3 0.42 10.4 0.9 5.4 5 1 1 6 6 6 2 Leucine rich repeat SEN1_N PF12726.7 RJW60062.1 - 0.11 10.7 0.2 0.17 10.1 0.2 1.2 1 0 0 1 1 1 0 SEN1 N terminal SDA1 PF05285.12 RJW60062.1 - 0.54 9.6 9.6 0.9 8.9 9.6 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 RJW60062.1 - 0.58 9.4 9.5 1 8.6 9.5 1.3 1 0 0 1 1 1 0 BUD22 Pkinase_Tyr PF07714.17 RJW60066.1 - 1.1e-81 274.0 0.0 1.4e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW60066.1 - 2.2e-42 145.2 0.0 3.1e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RJW60066.1 - 4.7e-20 71.5 0.0 7.6e-17 61.2 0.0 2.6 2 0 0 2 2 2 2 SH2 domain SH3_1 PF00018.28 RJW60066.1 - 5.1e-12 45.2 0.1 1.1e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RJW60066.1 - 4.2e-11 42.5 0.2 1e-10 41.3 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RJW60066.1 - 4.8e-09 35.8 0.1 1.1e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 RJW60066.1 - 0.00083 19.7 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 Helically-extended SH3 domain Kinase-like PF14531.6 RJW60066.1 - 0.0011 18.4 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pertussis_S1 PF02917.14 RJW60066.1 - 0.0013 18.5 0.1 0.0026 17.6 0.1 1.4 1 0 0 1 1 1 1 Pertussis toxin, subunit 1 Kdo PF06293.14 RJW60066.1 - 0.0015 18.0 0.1 0.0023 17.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_10 PF17902.1 RJW60066.1 - 0.015 15.3 0.1 0.052 13.6 0.1 1.9 1 0 0 1 1 1 0 SH3 domain SH3_3 PF08239.11 RJW60066.1 - 0.041 14.2 1.5 0.087 13.1 1.5 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Haspin_kinase PF12330.8 RJW60066.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RJW60066.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Gtr1_RagA PF04670.12 RJW60067.1 - 1.7e-26 93.0 0.0 2.2e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_7 PF13499.6 RJW60069.1 - 3e-07 30.8 0.2 7.6e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair Dynein_light PF01221.18 RJW60069.1 - 7.6e-07 29.4 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_6 PF13405.6 RJW60069.1 - 0.0064 16.3 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RJW60069.1 - 0.035 13.7 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 EF hand Ribosomal_L30 PF00327.20 RJW60070.1 - 0.00034 20.4 0.1 0.0006 19.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e FAR1 PF03101.15 RJW60070.1 - 0.016 15.9 0.1 0.036 14.7 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain HXXSHH PF07586.11 RJW60070.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) TRF PF08558.10 RJW60070.1 - 0.21 11.1 0.9 14 5.2 0.1 2.2 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) DUF5575 PF17738.1 RJW60070.1 - 0.22 10.5 2.5 1.7 7.6 2.5 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5575) Antimicrobial_1 PF08018.11 RJW60071.1 - 0.54 10.5 5.5 1 9.6 5.5 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide Exo_endo_phos PF03372.23 RJW60073.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Dynein_light PF01221.18 RJW60074.1 - 5.8e-16 58.6 0.0 9.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 RJW60074.1 - 7.3e-10 39.2 0.4 1.6e-09 38.0 0.4 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW60074.1 - 6.1e-08 32.0 0.2 0.016 15.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RJW60074.1 - 1.7e-07 30.3 0.7 0.0072 15.8 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW60074.1 - 0.0046 16.8 0.5 0.014 15.3 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain pair rve PF00665.26 RJW60074.1 - 0.015 15.4 0.0 2.7 8.2 0.0 2.4 1 1 0 1 1 1 0 Integrase core domain EF-hand_9 PF14658.6 RJW60074.1 - 0.043 14.2 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 RJW60074.1 - 0.06 12.9 0.7 0.24 11.0 0.0 2.2 3 0 0 3 3 3 0 EF hand Hexapep PF00132.24 RJW60075.1 - 2.3e-13 49.3 15.8 9.6e-05 22.0 0.8 4.9 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RJW60075.1 - 8.8e-07 28.6 10.6 0.005 16.6 0.2 3.5 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 RJW60075.1 - 0.0088 15.0 2.6 0.025 13.5 0.1 2.0 1 1 1 2 2 2 1 L-fucokinase DUF4954 PF16314.5 RJW60075.1 - 0.018 13.2 1.2 0.027 12.6 0.8 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) GYF PF02213.16 RJW60077.1 - 1.2e-12 47.3 0.0 2.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 GYF domain RPS31 PF17067.5 RJW60077.1 - 1.6 9.0 8.1 0.11 12.6 0.8 2.7 2 0 0 2 2 2 0 Ribosomal protein S31e DER1 PF04511.15 RJW60078.1 - 6.3e-64 215.4 20.0 7.3e-64 215.2 20.0 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 RJW60078.1 - 0.055 13.2 0.4 0.055 13.2 0.4 1.9 1 1 1 2 2 2 0 Oleosin DUF1751 PF08551.10 RJW60078.1 - 1.1 9.9 13.4 0.18 12.4 9.1 2.0 2 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Glyco_hydro_15 PF00723.21 RJW60084.1 - 2.1e-26 92.7 0.0 2.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Scytalone_dh PF02982.14 RJW60085.1 - 0.00059 19.7 20.0 8.8 6.1 0.2 5.4 5 0 0 5 5 5 5 Scytalone dehydratase TPR_2 PF07719.17 RJW60086.1 - 8.6e-11 41.1 0.7 0.016 15.3 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RJW60086.1 - 4.5e-08 32.6 0.7 0.00038 20.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RJW60086.1 - 0.00018 21.1 2.8 0.02 14.5 1.1 2.5 2 0 0 2 2 2 2 TPR repeat FKBP_C PF00254.28 RJW60086.1 - 0.00021 21.6 0.0 0.00038 20.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_8 PF13181.6 RJW60086.1 - 0.00041 20.4 0.5 1.4 9.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RJW60086.1 - 0.0011 19.4 3.8 0.067 13.7 0.2 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 RJW60086.1 - 0.004 17.6 1.4 0.0071 16.8 0.1 2.0 3 0 0 3 3 3 1 Bacterial transcriptional activator domain MIT PF04212.18 RJW60086.1 - 0.014 15.4 0.1 0.082 13.0 0.1 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 RJW60086.1 - 0.018 15.2 0.4 1.1 9.5 0.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 RJW60086.1 - 0.019 15.6 3.6 1.2 9.9 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RJW60086.1 - 0.046 14.1 0.6 0.88 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RJW60086.1 - 0.089 13.7 4.0 13 6.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ErmC PF06308.11 RJW60086.1 - 0.11 12.9 0.5 0.21 12.0 0.5 1.5 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) Profilin PF00235.19 RJW60087.1 - 3.7e-08 33.7 0.0 7.1e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Profilin Claudin_2 PF13903.6 RJW60089.1 - 1.5e-08 34.6 8.7 2.3e-08 34.0 8.4 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Bac_export_2 PF01312.19 RJW60089.1 - 0.51 9.5 6.1 0.76 8.9 6.1 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Lactamase_B_2 PF12706.7 RJW60090.1 - 3.6e-11 43.0 0.0 0.00028 20.4 0.0 2.8 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RJW60090.1 - 1.8e-06 28.1 0.4 1.2e-05 25.4 0.0 2.4 2 2 1 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 RJW60090.1 - 4.7e-05 23.0 0.0 0.00015 21.4 0.0 1.8 2 0 0 2 2 2 1 tRNase Z endonuclease PDEase_II PF02112.15 RJW60090.1 - 0.26 10.4 0.0 2.7 7.0 0.0 1.9 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Adap_comp_sub PF00928.21 RJW60091.1 - 5.1e-92 308.0 0.1 7.5e-92 307.4 0.1 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RJW60091.1 - 1.4e-08 34.7 2.2 2.4e-08 34.0 2.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sema PF01403.19 RJW60093.1 - 3.8e-22 78.7 0.0 5.9e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.19 RJW60093.1 - 1.9 8.8 14.0 0.067 13.4 5.4 2.8 2 0 0 2 2 2 0 Thrombospondin type 1 domain Tubulin PF00091.25 RJW60094.1 - 5.6e-65 219.2 0.0 7.7e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW60094.1 - 3.4e-50 169.4 0.0 5.9e-50 168.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW60094.1 - 0.0072 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain RVT_1 PF00078.27 RJW60095.1 - 4.3e-89 297.8 0.0 1.4e-45 155.5 0.0 3.1 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) EMP24_GP25L PF01105.24 RJW60095.1 - 8.4e-28 97.5 0.2 1.6e-27 96.6 0.2 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Exo_endo_phos_2 PF14529.6 RJW60095.1 - 2.4e-20 72.6 0.1 9.9e-11 41.5 0.0 3.2 4 0 0 4 4 4 2 Endonuclease-reverse transcriptase Trp_oprn_chp PF09534.10 RJW60096.1 - 0.2 11.4 0.0 0.77 9.5 0.0 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PCI PF01399.27 RJW60097.1 - 3.1e-24 85.5 1.6 3.1e-24 85.5 1.6 2.1 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 RJW60097.1 - 0.002 18.1 0.1 0.0043 17.0 0.1 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TPR_2 PF07719.17 RJW60097.1 - 0.13 12.4 0.9 28 5.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat FliS PF02561.14 RJW60097.1 - 0.43 10.9 8.5 0.18 12.1 4.0 2.7 3 0 0 3 3 3 0 Flagellar protein FliS ACDC PF14733.6 RJW60097.1 - 0.67 10.3 6.5 16 5.9 0.6 3.7 3 1 1 4 4 4 0 AP2-coincident C-terminal Seryl_tRNA_N PF02403.22 RJW60098.1 - 0.00088 19.5 6.1 0.0016 18.7 2.5 2.3 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain PUB PF09409.10 RJW60098.1 - 0.02 14.8 0.0 0.077 12.9 0.0 1.9 1 0 0 1 1 1 0 PUB domain FTA4 PF13093.6 RJW60098.1 - 0.095 12.6 2.9 0.051 13.5 0.9 1.6 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 She9_MDM33 PF05546.11 RJW60098.1 - 0.096 12.5 8.7 0.017 14.9 4.6 1.8 2 1 0 2 2 2 0 She9 / Mdm33 family Phage_GP20 PF06810.11 RJW60098.1 - 0.16 11.8 1.6 7 6.5 0.1 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Thioredoxin_4 PF13462.6 RJW60098.1 - 0.27 11.4 2.4 4 7.6 0.7 2.2 1 1 1 2 2 2 0 Thioredoxin DHR10 PF18595.1 RJW60098.1 - 0.34 11.0 10.4 0.36 10.9 5.9 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain SKA2 PF16740.5 RJW60098.1 - 0.85 9.4 6.2 0.24 11.2 0.7 2.6 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 PRKG1_interact PF15898.5 RJW60098.1 - 1.4 9.8 10.1 30 5.6 4.1 3.1 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF16 PF01519.16 RJW60098.1 - 2.9 8.4 6.5 0.76 10.3 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 MFAP1 PF06991.11 RJW60099.1 - 3.9e-69 232.8 22.8 3.9e-69 232.8 22.8 2.9 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Guanylate_kin PF00625.21 RJW60103.1 - 3e-52 176.9 0.0 4.7e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 RJW60103.1 - 2e-07 31.3 0.0 2.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RJW60103.1 - 1.7e-06 28.0 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RJW60103.1 - 4.1e-05 24.0 0.1 6.3e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 RJW60103.1 - 8.2e-05 23.2 0.0 0.00019 21.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW60103.1 - 0.00015 22.0 0.1 0.00081 19.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RJW60103.1 - 0.0006 19.5 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RJW60103.1 - 0.00061 19.8 0.0 0.00098 19.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 RJW60103.1 - 0.00068 20.2 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 RJW60103.1 - 0.0014 18.5 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_7 PF12775.7 RJW60103.1 - 0.0033 17.0 0.1 0.0051 16.3 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RJW60103.1 - 0.005 17.2 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 RJW60103.1 - 0.0087 16.1 0.0 0.024 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 RJW60103.1 - 0.0097 15.1 0.3 0.077 12.2 0.1 2.0 1 1 1 2 2 2 1 NB-ARC domain NACHT PF05729.12 RJW60103.1 - 0.017 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 RJW60103.1 - 0.024 15.0 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 RJW60103.1 - 0.042 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RJW60103.1 - 0.045 13.7 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 RJW60103.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 RJW60103.1 - 0.063 12.9 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 RJW60103.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 RJW60103.1 - 0.077 12.8 0.0 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system KAP_NTPase PF07693.14 RJW60103.1 - 0.092 12.0 0.1 0.21 10.8 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.6 RJW60103.1 - 0.096 12.2 0.3 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RJW60103.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RJW60103.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 RJW60103.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 RJW60103.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_23 PF13476.6 RJW60103.1 - 0.18 12.3 0.1 0.35 11.3 0.0 1.5 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 RJW60103.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 RJW60103.1 - 0.19 12.1 0.1 0.46 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Lysyl_oxidase PF01186.17 RJW60104.1 - 2.1e-79 265.9 0.2 3.2e-79 265.4 0.2 1.3 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.18 RJW60104.1 - 6.3e-34 116.5 7.1 3.3e-27 94.9 0.6 3.2 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 RJW60104.1 - 1.6e-07 31.8 4.0 1.6e-05 25.3 0.4 2.9 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 RJW60104.1 - 0.041 14.4 0.1 0.91 10.1 0.0 2.7 3 0 0 3 3 3 0 Hepsin, SRCR domain Ank_2 PF12796.7 RJW60106.1 - 3.8e-19 69.1 1.5 1.5e-09 38.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW60106.1 - 4.4e-16 59.0 4.3 2.9e-06 27.7 0.8 3.6 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW60106.1 - 4.7e-14 52.3 5.7 3.9e-08 33.4 0.7 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW60106.1 - 7.4e-14 50.5 3.1 0.0017 18.7 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RJW60106.1 - 1e-12 47.9 3.6 0.00012 22.3 0.3 4.3 4 0 0 4 4 4 2 Ankyrin repeat RhoGEF PF00621.20 RJW60108.1 - 1.6e-09 38.3 5.8 1.6e-09 38.3 5.8 2.6 3 0 0 3 3 3 1 RhoGEF domain SH3_1 PF00018.28 RJW60108.1 - 1.6e-07 30.8 0.0 3.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RJW60108.1 - 9.3e-07 28.6 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RJW60108.1 - 0.00052 19.6 0.0 0.0015 18.2 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 RJW60108.1 - 0.0078 16.5 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Peptidase_M28 PF04389.17 RJW60110.1 - 4e-17 62.6 0.0 2.3e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.15 RJW60110.1 - 0.0026 17.8 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain bZIP_2 PF07716.15 RJW60111.1 - 3.5e-11 43.0 10.8 3.5e-11 43.0 10.8 1.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 RJW60111.1 - 0.049 13.7 9.0 0.076 13.1 9.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor zf-C2H2_4 PF13894.6 RJW60113.1 - 0.021 15.6 0.9 0.086 13.7 0.9 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW60113.1 - 0.041 14.4 1.2 0.041 14.4 1.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 RJW60113.1 - 0.065 13.7 1.7 0.15 12.5 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Macro PF01661.21 RJW60115.1 - 0.073 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Macro domain 7tm_1 PF00001.21 RJW60116.1 - 4.2e-08 32.8 12.7 7.5e-08 32.0 11.4 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW60116.1 - 1.6e-05 24.3 25.5 3.3e-05 23.3 12.0 2.8 3 1 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RJW60116.1 - 2.7e-05 23.9 16.7 2.7e-05 23.9 16.7 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3309 PF11752.8 RJW60116.1 - 0.03 14.4 2.2 0.077 13.0 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Homeodomain PF00046.29 RJW60117.1 - 0.0016 18.2 0.0 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RJW60117.1 - 0.0059 16.5 0.1 0.017 15.0 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain cNMP_binding PF00027.29 RJW60118.1 - 5e-21 74.6 0.1 3.2e-14 52.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 RJW60118.1 - 0.00064 19.3 0.5 0.0014 18.2 0.5 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit CUT PF02376.15 RJW60120.1 - 1.1e-31 108.8 0.6 2.2e-31 107.9 0.6 1.5 1 0 0 1 1 1 1 CUT domain KRE1 PF17056.5 RJW60120.1 - 0.074 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 SCO1-SenC PF02630.14 RJW60124.1 - 3.1e-45 153.4 0.0 4.7e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 RJW60124.1 - 1.6e-05 24.8 0.1 0.00013 21.9 0.1 2.4 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RJW60124.1 - 0.0019 18.5 0.0 0.0045 17.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 RJW60124.1 - 0.062 13.0 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Redoxin RVT_1 PF00078.27 RJW60124.1 - 0.14 11.7 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CEP170_C PF15308.6 RJW60126.1 - 0.0021 16.8 0.0 0.0027 16.3 0.0 1.1 1 0 0 1 1 1 1 CEP170 C-terminus PGM_PMM_II PF02879.16 RJW60129.1 - 1.3e-19 70.7 0.0 4e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.16 RJW60129.1 - 7.7e-16 58.1 0.0 4.7e-15 55.5 0.0 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 RJW60129.1 - 4.7e-13 49.3 0.0 1.1e-12 48.2 0.0 1.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 RJW60129.1 - 5.4e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Sec7 PF01369.20 RJW60132.1 - 1.6e-50 171.3 0.0 2.6e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 RJW60132.1 - 3.7e-09 36.7 0.0 5.5e-08 32.9 0.0 2.4 1 1 0 1 1 1 1 PH domain Complex1_LYR PF05347.15 RJW60133.1 - 1.5e-12 47.4 0.2 2.4e-12 46.7 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RJW60133.1 - 1.5e-07 32.0 2.5 3.1e-07 31.1 2.5 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Caudo_TAP PF02413.17 RJW60133.1 - 0.053 13.7 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Ubiq_cyt_C_chap PF03981.12 RJW60133.1 - 0.098 12.7 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone fn3 PF00041.21 RJW60135.1 - 1.4e-19 70.2 6.9 3.5e-09 36.9 0.0 5.8 5 2 0 5 5 5 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW60135.1 - 2.1e-07 31.4 2.0 0.065 13.8 0.0 5.0 5 1 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain DUF4945 PF16303.5 RJW60135.1 - 0.029 14.3 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) DUF2369 PF10179.9 RJW60135.1 - 0.18 12.2 0.2 1.3e+02 3.1 0.1 4.0 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) B-block_TFIIIC PF04182.12 RJW60139.1 - 1.9e-07 31.1 0.1 7.8e-05 22.8 0.0 3.4 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC TIMP PF00965.17 RJW60139.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase CDP-OH_P_transf PF01066.21 RJW60140.1 - 9.6e-12 45.5 0.8 9.6e-12 45.5 0.8 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Meis_PKNOX_N PF16493.5 RJW60141.1 - 2.1e-33 114.5 1.1 4.2e-33 113.6 1.1 1.4 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 RJW60141.1 - 2.9e-20 71.9 1.0 6.5e-20 70.8 1.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RJW60141.1 - 6.1e-08 32.4 1.1 1.3e-07 31.3 0.4 1.9 2 0 0 2 2 2 1 Homeodomain MRG PF05712.13 RJW60144.1 - 2.8e-44 150.8 0.1 4.1e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 MRG Pex14_N PF04695.13 RJW60144.1 - 6.1 7.5 10.9 13 6.4 10.9 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Galactosyl_T PF01762.21 RJW60146.1 - 7.1e-40 136.9 0.0 8.8e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 RJW60146.1 - 0.13 11.7 0.0 0.33 10.3 0.0 1.6 1 1 0 1 1 1 0 Fringe-like Fzo_mitofusin PF04799.13 RJW60147.1 - 1.2e-48 164.7 3.2 2.7e-48 163.5 0.6 2.4 2 0 0 2 2 2 1 fzo-like conserved region RVT_1 PF00078.27 RJW60147.1 - 7.3e-24 84.5 0.0 1.5e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dynamin_N PF00350.23 RJW60147.1 - 2.1e-23 83.2 0.0 1.5e-22 80.4 0.0 2.4 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 RJW60147.1 - 2.9e-07 30.5 0.0 1.6e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase ECM11 PF15463.6 RJW60147.1 - 0.0018 18.9 0.5 0.53 10.9 0.1 2.7 2 0 0 2 2 2 2 Extracellular mutant protein 11 zf-C4H2 PF10146.9 RJW60147.1 - 1 9.6 5.5 0.52 10.6 0.5 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein zf-C3HC4_3 PF13920.6 RJW60150.1 - 0.68 9.8 7.2 0.086 12.7 1.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Macro PF01661.21 RJW60152.1 - 2.3e-34 118.0 0.4 3.2e-34 117.5 0.4 1.2 1 0 0 1 1 1 1 Macro domain Lig_chan PF00060.26 RJW60153.1 - 6.5e-51 172.1 0.3 9.2e-51 171.6 0.3 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RJW60153.1 - 6.5e-37 126.2 0.1 1.1e-36 125.5 0.1 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RJW60153.1 - 1.4e-18 67.1 0.0 2.5e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SH3_17 PF18350.1 RJW60153.1 - 0.0093 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease SH3 domain DUF5409 PF17421.2 RJW60153.1 - 0.016 15.9 0.1 0.64 10.8 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5409) Tubulin PF00091.25 RJW60155.1 - 5.1e-68 229.2 0.0 7.5e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW60155.1 - 7.8e-46 155.3 0.1 1.4e-45 154.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RJW60155.1 - 0.00065 20.0 0.0 0.002 18.4 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 RJW60155.1 - 0.034 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Gag_spuma PF03276.14 RJW60159.1 - 0.011 14.2 1.2 0.016 13.7 1.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein PP1_inhibitor PF05361.12 RJW60161.1 - 0.0081 16.2 0.7 0.01 15.9 0.7 1.2 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Nudc_N PF14050.6 RJW60162.1 - 0.032 14.2 3.6 2.8 8.0 0.5 2.7 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. MdcG PF10620.9 RJW60162.1 - 0.1 12.4 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG Pkinase PF00069.25 RJW60163.1 - 6.9e-55 186.2 0.0 9.4e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60163.1 - 1.4e-23 83.5 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RJW60163.1 - 1.5e-05 25.5 0.0 3.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 RJW60163.1 - 0.0087 14.9 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW60163.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Cadherin PF00028.17 RJW60164.1 - 5.8e-53 177.3 10.8 2e-11 44.2 0.0 11.9 10 4 0 10 10 10 7 Cadherin domain Cadherin_2 PF08266.12 RJW60164.1 - 1.8e-15 56.5 0.0 2.6e-06 27.2 0.0 5.3 4 1 0 4 4 4 3 Cadherin-like Cadherin_3 PF16184.5 RJW60164.1 - 3.1e-06 27.2 5.6 5.4 7.1 0.0 6.7 6 0 0 6 6 6 2 Cadherin-like DUF2207 PF09972.9 RJW60164.1 - 0.031 13.0 0.0 0.06 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PBP PF01161.20 RJW60164.1 - 0.047 14.0 0.0 0.62 10.4 0.0 2.8 1 1 1 2 2 2 0 Phosphatidylethanolamine-binding protein EphA2_TM PF14575.6 RJW60164.1 - 0.077 13.9 0.0 0.22 12.4 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4307 PF14155.6 RJW60164.1 - 0.087 12.7 0.0 0.5 10.2 0.0 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Ly49 PF08391.10 RJW60164.1 - 0.15 12.4 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region RVT_1 PF00078.27 RJW60165.1 - 0.00021 20.9 0.0 0.0016 18.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dynein_light PF01221.18 RJW60166.1 - 1.1e-13 51.3 0.5 1.9e-13 50.5 0.5 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 RJW60166.1 - 2.2e-13 50.5 0.3 4.1e-13 49.6 0.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW60166.1 - 5.3e-13 47.5 1.7 2e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW60166.1 - 8.2e-11 40.9 0.7 2.4e-05 23.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RJW60166.1 - 2.3e-10 39.5 1.4 0.0005 19.4 0.8 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW60166.1 - 1.4e-07 31.2 2.2 0.00021 21.1 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW60166.1 - 4.9e-07 30.1 0.2 1.1e-06 28.9 0.2 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW60166.1 - 0.027 14.4 1.5 0.13 12.2 0.2 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand NUDIX PF00293.28 RJW60168.1 - 2.5e-07 30.8 0.0 3.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ArsA_ATPase PF02374.15 RJW60170.1 - 2.7e-109 365.0 0.4 5.4e-94 314.8 0.0 2.0 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 RJW60170.1 - 8.5e-11 42.1 0.0 2.2e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 RJW60170.1 - 8.9e-09 35.5 0.0 2.3e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 RJW60170.1 - 2e-05 24.1 0.2 0.00071 19.1 0.0 2.8 2 1 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 RJW60170.1 - 6.5e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 RJW60170.1 - 0.00035 20.1 0.0 0.0013 18.2 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 RJW60170.1 - 0.019 14.2 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 RJW60170.1 - 0.044 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 RJW60170.1 - 0.086 12.4 0.1 0.15 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain Phage_holin_3_1 PF05106.12 RJW60170.1 - 0.14 12.6 0.0 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) SRP54 PF00448.22 RJW60170.1 - 0.14 11.8 0.0 0.44 10.1 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 RJW60170.1 - 0.19 11.0 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RasGAP PF00616.19 RJW60171.1 - 5e-32 111.3 0.2 1.2e-30 106.8 0.2 2.4 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 RJW60171.1 - 3.3e-05 24.1 0.0 7.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Yippee-Mis18 PF03226.14 RJW60174.1 - 2.1e-13 50.4 0.7 3e-13 49.9 0.7 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Jas PF16135.5 RJW60174.1 - 0.052 13.7 0.1 0.052 13.7 0.1 1.8 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling Pkinase PF00069.25 RJW60175.1 - 8.1e-73 245.0 0.0 1.2e-72 244.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60175.1 - 7.3e-42 143.4 0.0 1.3e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 RJW60175.1 - 7.5e-12 44.9 0.0 1.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 RJW60175.1 - 2.3e-06 27.1 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RJW60175.1 - 0.0091 15.6 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 RJW60175.1 - 0.026 13.5 0.0 0.026 13.5 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain YukC PF10140.9 RJW60175.1 - 0.08 11.8 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 RJW60175.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MRF_C1 PF13887.6 RJW60178.1 - 0.043 13.0 0.0 0.099 11.8 0.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 DNTTIP1_dimer PF18192.1 RJW60179.1 - 4.4e-25 87.8 0.5 7.4e-25 87.1 0.5 1.4 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain SWIM PF04434.17 RJW60183.1 - 0.016 14.9 0.2 0.016 14.9 0.2 1.9 2 0 0 2 2 2 0 SWIM zinc finger Neuromodulin PF06614.11 RJW60183.1 - 0.024 14.8 0.2 0.039 14.1 0.2 1.2 1 0 0 1 1 1 0 Neuromodulin Y_phosphatase PF00102.27 RJW60184.1 - 8.8e-110 365.8 0.1 2.8e-77 259.5 1.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 RJW60184.1 - 4.2e-23 81.5 0.5 3.2e-06 27.4 0.0 4.5 4 0 0 4 4 4 3 Fibronectin type III domain Ig_3 PF13927.6 RJW60184.1 - 5e-05 23.8 0.3 0.00024 21.6 0.3 2.3 1 0 0 1 1 1 1 Immunoglobulin domain DSPc PF00782.20 RJW60184.1 - 7.4e-05 22.6 0.0 0.00029 20.6 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain ig PF00047.25 RJW60184.1 - 0.00092 19.3 0.2 0.0027 17.8 0.2 1.8 1 0 0 1 1 1 1 Immunoglobulin domain PTPlike_phytase PF14566.6 RJW60184.1 - 0.028 14.6 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate I-set PF07679.16 RJW60184.1 - 0.032 14.3 0.1 0.08 13.0 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain Y_phosphatase3 PF13350.6 RJW60184.1 - 0.037 14.0 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family fn3_2 PF16893.5 RJW60184.1 - 0.051 13.7 0.2 26 5.0 0.0 3.4 3 0 0 3 3 3 0 Fibronectin type III domain Ig_2 PF13895.6 RJW60184.1 - 0.054 13.8 0.7 0.15 12.4 0.3 2.0 2 0 0 2 2 2 0 Immunoglobulin domain Vault PF01505.18 RJW60185.1 - 5.4e-49 164.1 4.2 1.7e-13 50.5 0.0 5.1 5 0 0 5 5 5 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 RJW60185.1 - 7.1e-48 161.5 0.0 1.2e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 RJW60185.1 - 1.7e-34 117.7 1.6 2.4e-31 107.6 0.1 3.3 4 0 0 4 4 4 2 Major Vault Protein Repeat domain Vault_2 PF17794.1 RJW60185.1 - 1.5e-33 114.9 0.2 6e-19 68.2 0.1 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 RJW60185.1 - 4e-26 90.9 0.3 5.1e-24 84.1 0.1 3.6 4 0 0 4 4 4 1 Major Vault Protein repeat domain DUF3601 PF12208.8 RJW60185.1 - 0.051 13.7 0.0 20 5.4 0.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3601) STT3 PF02516.14 RJW60186.1 - 4.8e-76 256.6 20.7 6.1e-73 246.4 17.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Exo_endo_phos PF03372.23 RJW60187.1 - 4.3e-16 59.1 0.0 1.2e-15 57.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IBR PF01485.21 RJW60188.1 - 1.8e-21 76.1 22.4 2e-11 43.9 1.1 3.7 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain RWD PF05773.22 RJW60188.1 - 2.3e-12 47.2 0.0 4.8e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.6 RJW60188.1 - 0.024 14.6 1.4 0.024 14.6 1.4 4.4 4 1 0 4 4 4 0 zinc-RING finger domain RVT_1 PF00078.27 RJW60189.1 - 2.8e-07 30.3 0.0 4.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_LYR PF05347.15 RJW60190.1 - 1.2e-08 34.8 2.0 3.1e-08 33.5 2.0 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RJW60190.1 - 0.0023 18.7 0.2 0.0044 17.7 0.2 1.5 1 0 0 1 1 1 1 Complex1_LYR-like CK_II_beta PF01214.18 RJW60191.1 - 1.2e-81 272.9 0.1 1.4e-81 272.7 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PRKCSH PF07915.13 RJW60192.1 - 5e-13 49.9 0.5 1.3e-12 48.5 0.5 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 RJW60192.1 - 2.2e-06 27.4 0.1 4.2e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein XRCC4 PF06632.12 RJW60192.1 - 0.085 11.7 2.0 0.13 11.1 2.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RRN3 PF05327.11 RJW60192.1 - 0.35 9.4 3.5 0.59 8.6 3.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4611 PF15387.6 RJW60192.1 - 1.6 9.0 6.2 2.7 8.3 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) DUF1899 PF08953.11 RJW60193.1 - 6.1e-32 109.3 0.0 1.1e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 RJW60193.1 - 2.1e-20 72.4 0.2 3.9e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 RJW60193.1 - 6.5e-09 36.3 2.6 0.0067 17.3 0.3 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW60193.1 - 1.7e-05 25.0 0.1 0.18 12.1 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Vps54 PF07928.12 RJW60194.1 - 0.022 15.2 0.1 0.03 14.8 0.1 1.1 1 0 0 1 1 1 0 Vps54-like protein MFS_1 PF07690.16 RJW60195.1 - 7.3e-31 107.4 41.2 4.3e-21 75.2 11.1 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily RVT_1 PF00078.27 RJW60196.1 - 7.9e-08 32.1 0.0 1.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UQ_con PF00179.26 RJW60197.1 - 6.1e-51 171.8 0.0 7e-51 171.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RJW60197.1 - 0.098 12.9 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 RJW60197.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Ras PF00071.22 RJW60198.1 - 2.3e-46 157.3 0.0 2.9e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW60198.1 - 1.6e-21 76.7 0.0 2.8e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW60198.1 - 2.6e-10 40.0 0.0 3.4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW60198.1 - 0.00056 19.5 0.1 0.0008 19.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF1541 PF07563.11 RJW60198.1 - 0.13 12.2 0.1 0.39 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Dynein_light PF01221.18 RJW60199.1 - 2.2e-17 63.2 2.0 3.4e-17 62.5 2.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 RJW60199.1 - 2.8e-09 37.3 10.2 1e-07 32.3 3.5 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW60199.1 - 4e-08 32.6 5.6 0.005 16.7 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 RJW60199.1 - 4.9e-07 28.9 8.2 0.0017 17.7 0.7 2.8 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 RJW60199.1 - 2e-06 28.1 1.2 2e-06 28.1 1.2 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 RJW60199.1 - 0.00017 20.9 8.1 0.0016 17.9 0.2 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RJW60199.1 - 0.0017 18.2 3.9 0.12 12.3 0.3 2.6 1 1 1 2 2 2 2 EF-hand domain pair PhetRS_B1 PF18262.1 RJW60199.1 - 0.0086 16.3 1.1 0.047 13.9 0.1 2.3 1 1 1 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain Fzo_mitofusin PF04799.13 RJW60199.1 - 0.0091 15.6 0.4 0.015 14.8 0.4 1.3 1 0 0 1 1 1 1 fzo-like conserved region Flavodoxin_NdrI PF07972.11 RJW60199.1 - 0.027 14.6 0.1 0.063 13.5 0.0 1.7 2 0 0 2 2 2 0 NrdI Flavodoxin like VIT1 PF01988.19 RJW60199.1 - 0.07 13.0 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 VIT family Pex14_N PF04695.13 RJW60199.1 - 0.16 12.6 0.5 0.3 11.7 0.5 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Vel1p PF10339.9 RJW60201.1 - 0.014 14.8 0.1 1.9 7.8 0.0 2.4 3 0 0 3 3 3 0 Yeast-specific zinc responsive Frag1 PF10277.9 RJW60202.1 - 1.6e-06 27.9 7.4 1.9e-06 27.6 7.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Collagen PF01391.18 RJW60203.1 - 6.6e-05 22.6 8.9 0.00011 21.9 8.9 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) SMAP PF15477.6 RJW60204.1 - 4.2e-13 50.0 0.5 2.1e-12 47.8 0.5 2.3 1 0 0 1 1 1 1 Small acidic protein family Ran_BP1 PF00638.18 RJW60205.1 - 9.8e-41 138.8 0.1 1.6e-40 138.1 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 RJW60205.1 - 0.0055 16.6 0.1 0.0093 15.9 0.1 1.4 1 1 0 1 1 1 1 WH1 domain ATP-synt_ab PF00006.25 RJW60206.1 - 3.3e-105 350.4 0.0 4.9e-105 349.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 RJW60206.1 - 1.7e-43 147.3 0.0 3.1e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 RJW60206.1 - 3.3e-14 53.2 1.4 9.9e-14 51.6 1.4 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LSM PF01423.22 RJW60208.1 - 2.9e-16 58.9 0.1 3.7e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Kunitz_BPTI PF00014.23 RJW60209.1 - 9.1e-29 99.5 21.3 4.2e-14 52.5 12.1 2.4 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Mto2_bdg PF12808.7 RJW60210.1 - 0.027 14.8 0.4 0.07 13.4 0.4 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RVT_1 PF00078.27 RJW60211.1 - 7.3e-28 97.6 0.0 1.3e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Laminin_G_2 PF02210.24 RJW60212.1 - 1.5e-56 190.4 0.0 1.3e-15 58.1 0.1 4.7 4 1 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.23 RJW60212.1 - 3.6e-43 146.9 0.0 4.8e-13 49.4 0.0 5.6 5 1 0 5 5 5 4 Laminin G domain Laminin_G_3 PF13385.6 RJW60212.1 - 6.4e-07 29.6 0.6 0.0017 18.5 0.0 3.6 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Phage_head_chap PF11113.8 RJW60212.1 - 0.068 13.3 0.0 5.1 7.3 0.0 3.1 3 0 0 3 3 3 0 Head assembly gene product EGF PF00008.27 RJW60212.1 - 0.16 12.3 23.0 0.091 13.1 8.5 3.1 3 0 0 3 3 3 0 EGF-like domain Exo_endo_phos_2 PF14529.6 RJW60214.1 - 3.8e-06 26.7 0.0 5.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase EF-hand_7 PF13499.6 RJW60215.1 - 8.5e-21 74.2 0.9 3.4e-10 40.2 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW60215.1 - 3.1e-20 70.1 1.0 2.2e-05 23.7 0.0 5.3 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 RJW60215.1 - 6.1e-19 66.3 0.1 8.4e-06 25.3 0.0 5.4 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 RJW60215.1 - 1.5e-13 50.3 1.4 5.7e-06 26.1 0.0 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW60215.1 - 1.2e-09 37.2 0.0 0.0027 17.1 0.0 3.8 4 0 0 4 4 4 3 EF hand HipA_C PF07804.12 RJW60215.1 - 0.015 15.0 0.5 1.1 8.9 0.2 2.1 1 1 1 2 2 2 0 HipA-like C-terminal domain DUF3512 PF12024.8 RJW60217.1 - 3.2e-15 56.3 0.0 6.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 RJW60217.1 - 0.0022 18.0 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Sec7 PF01369.20 RJW60218.1 - 3.8e-28 98.4 0.0 6.3e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 RJW60218.1 - 8.8e-10 38.7 0.0 1.1e-06 28.7 0.2 2.4 2 0 0 2 2 2 2 PH domain T-box_assoc PF16176.5 RJW60219.1 - 0.0062 16.6 1.7 0.5 10.4 0.2 2.4 1 1 2 3 3 3 3 T-box transcription factor-associated Metallothio_Euk PF12749.7 RJW60219.1 - 2.2 8.5 5.4 22 5.3 0.4 2.5 1 1 1 2 2 2 0 Eukaryotic metallothionein RVT_1 PF00078.27 RJW60221.1 - 5.9e-19 68.5 0.0 9.8e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3421 PF11901.8 RJW60225.1 - 8.3e-31 106.4 0.0 3.7e-30 104.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3421) MFS_1 PF07690.16 RJW60228.1 - 1.9e-35 122.4 44.0 1.6e-28 99.6 28.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RJW60228.1 - 3.7e-10 39.2 20.8 2.5e-08 33.2 20.8 2.7 1 1 0 1 1 1 1 MFS_1 like family Polysacc_synt_3 PF13440.6 RJW60228.1 - 0.0009 18.5 0.1 0.0009 18.5 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Dynein_light PF01221.18 RJW60229.1 - 1.3e-16 60.7 0.1 1.7e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3646 PF12362.8 RJW60229.1 - 0.052 13.9 0.0 0.078 13.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal UQ_con PF00179.26 RJW60230.1 - 8.6e-12 44.9 0.1 2.1e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme ARD PF03079.14 RJW60230.1 - 0.0036 17.5 0.1 0.023 14.9 0.0 2.1 1 1 1 2 2 2 1 ARD/ARD' family DUF1616 PF07760.11 RJW60230.1 - 0.21 10.9 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Dynein_light PF01221.18 RJW60231.1 - 3.7e-14 52.8 0.1 6.7e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_1 PF00036.32 RJW60231.1 - 5.7e-12 44.3 2.5 1.8e-05 23.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW60231.1 - 9.3e-11 42.0 1.2 1.9e-10 41.0 1.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RJW60231.1 - 1.7e-10 39.9 0.6 6.9e-05 22.2 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW60231.1 - 5.1e-10 38.5 3.5 0.00024 20.8 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RJW60231.1 - 3.1e-05 23.7 2.9 0.0011 18.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW60231.1 - 0.00027 21.2 1.3 0.00056 20.2 0.3 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW60231.1 - 0.042 13.8 0.4 0.09 12.7 0.1 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ank_5 PF13857.6 RJW60232.1 - 4.1e-09 36.5 0.0 1.5e-08 34.7 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW60232.1 - 4.8e-08 33.5 0.0 8.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW60232.1 - 1.5e-07 31.2 0.0 6.3e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RJW60232.1 - 4.2e-07 30.1 0.0 4.1e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RJW60232.1 - 0.00018 22.0 0.0 0.00051 20.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SAC3_GANP PF03399.16 RJW60233.1 - 2e-105 352.4 1.3 2e-105 352.4 1.3 2.1 2 0 0 2 2 2 1 SAC3/GANP family RRM_1 PF00076.22 RJW60233.1 - 0.026 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSBP1 PF06825.12 RJW60233.1 - 0.033 14.1 0.1 0.13 12.2 0.1 2.1 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Sec3_C_2 PF15278.6 RJW60234.1 - 0.12 12.8 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Sec3 exocyst complex subunit rve PF00665.26 RJW60235.1 - 1.1e-16 61.1 0.1 1.5e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RJW60235.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain PhetRS_B1 PF18262.1 RJW60235.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 1 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Dynein_light PF01221.18 RJW60236.1 - 1.4e-15 57.3 0.0 2.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 RJW60236.1 - 2.7e-11 43.7 3.1 5.1e-11 42.9 3.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW60236.1 - 3.6e-10 38.6 5.1 0.00022 20.5 0.4 2.6 2 1 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 RJW60236.1 - 3.9e-10 38.8 2.7 0.00047 19.5 0.1 2.6 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW60236.1 - 1.8e-08 33.7 3.2 0.0002 21.0 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RJW60236.1 - 2.4e-06 27.8 0.2 5.2e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 RJW60236.1 - 2.8e-05 23.9 3.7 0.0051 16.6 0.6 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 RJW60236.1 - 0.0036 17.6 0.1 0.0088 16.3 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain SHMT PF00464.19 RJW60237.1 - 2.3e-144 480.9 0.0 2.7e-144 480.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF1732 PF08340.11 RJW60237.1 - 0.2 11.7 0.0 0.63 10.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) NIBRIN_BRCT_II PF16508.5 RJW60238.1 - 1e-25 90.4 0.0 1.9e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein BRCT_2 PF16589.5 RJW60238.1 - 0.056 13.9 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RJW60238.1 - 0.19 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain RVT_1 PF00078.27 RJW60239.1 - 3.1e-06 26.9 0.0 5.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AcetylCoA_hyd_C PF13336.6 RJW60240.1 - 1.2e-49 168.2 0.0 2.6e-49 167.1 0.0 1.5 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 RJW60240.1 - 1.8e-16 60.7 0.0 3.1e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Pollen_allerg_1 PF01357.21 RJW60242.1 - 0.086 12.9 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Pollen allergen L51_S25_CI-B8 PF05047.16 RJW60245.1 - 2.2e-08 33.9 0.1 4.4e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain T4SS_CagC PF16943.5 RJW60246.1 - 0.029 14.6 1.5 0.08 13.1 1.3 1.7 1 1 1 2 2 2 0 Cag pathogenicity island, type IV secretory system DUF1189 PF06691.11 RJW60246.1 - 0.032 13.8 0.4 0.046 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) EphA2_TM PF14575.6 RJW60246.1 - 0.41 11.6 1.4 1.5 9.8 0.6 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Asp4 PF16996.5 RJW60246.1 - 1.7 8.5 5.1 6.3 6.7 0.2 2.4 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 SET PF00856.28 RJW60247.1 - 7.7e-09 36.2 0.0 3.9e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 SET domain PHD PF00628.29 RJW60247.1 - 4.1e-06 26.6 15.3 1.3e-05 25.0 15.3 1.9 1 0 0 1 1 1 1 PHD-finger Ank_4 PF13637.6 RJW60248.1 - 6.2e-27 93.6 0.5 8.7e-11 42.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW60248.1 - 5e-19 68.7 0.0 4.6e-10 39.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW60248.1 - 3.7e-16 57.6 0.2 1.7e-06 27.9 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RJW60248.1 - 5.7e-14 52.0 0.5 1.7e-08 34.5 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RJW60248.1 - 1.4e-11 44.2 3.6 4.3e-05 23.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Nitro_FeMo-Co PF02579.17 RJW60248.1 - 0.024 14.9 0.1 0.055 13.8 0.1 1.7 1 1 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Nuc_deoxyri_tr2 PF15891.5 RJW60250.1 - 6e-21 74.8 0.3 1.1e-15 57.9 0.2 2.4 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like DEAD PF00270.29 RJW60252.1 - 2.1e-47 161.2 0.1 3e-47 160.6 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW60252.1 - 9.8e-22 77.4 0.0 4.4e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RJW60252.1 - 5.1e-11 42.6 0.1 1.1e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RJW60252.1 - 6.7e-09 36.0 0.0 2.4e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RJW60252.1 - 0.025 13.8 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 RJW60252.1 - 0.029 14.6 0.3 0.26 11.5 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RJW60252.1 - 0.094 12.4 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Innexin PF00876.18 RJW60253.1 - 1.4e-101 340.3 3.2 1.7e-101 340.1 3.2 1.0 1 0 0 1 1 1 1 Innexin SieB PF14163.6 RJW60253.1 - 0.079 12.4 2.8 0.74 9.3 1.0 2.4 2 0 0 2 2 2 0 Super-infection exclusion protein B 7TM_GPCR_Srd PF10317.9 RJW60255.1 - 0.00051 19.3 3.3 0.00063 19.0 3.3 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd ODV-E18 PF10717.9 RJW60255.1 - 8.3 6.4 10.5 1.8 8.5 0.0 2.1 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 OapA_N PF08525.11 RJW60255.1 - 9.8 6.3 12.1 12 6.0 0.0 2.7 2 1 0 2 2 2 0 Opacity-associated protein A N-terminal motif PPP1R35_C PF15503.6 RJW60258.1 - 1.6e-38 131.7 0.8 1.8e-38 131.6 0.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus Spectrin PF00435.21 RJW60260.1 - 4.9e-45 152.3 20.9 4.4e-16 59.3 1.3 4.3 4 0 0 4 4 4 4 Spectrin repeat EFhand_Ca_insen PF08726.10 RJW60260.1 - 1.4e-22 79.6 0.0 3.7e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 RJW60260.1 - 2.5e-07 29.8 0.6 0.00015 21.0 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RJW60260.1 - 3.7e-05 23.3 0.1 0.52 10.4 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RJW60260.1 - 5.1e-05 23.6 0.2 0.00098 19.5 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair Wtap PF17098.5 RJW60260.1 - 0.069 13.1 10.1 0.36 10.7 0.4 3.4 3 1 1 4 4 4 0 WTAP/Mum2p family Sec8_exocyst PF04048.14 RJW60260.1 - 0.19 11.6 5.5 0.23 11.4 0.3 3.2 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF4993 PF16384.5 RJW60261.1 - 0.065 12.2 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function HMG_box PF00505.19 RJW60262.1 - 3.3e-13 49.8 6.2 6.9e-07 29.6 0.3 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW60262.1 - 2.7e-12 47.1 6.4 4e-07 30.5 1.3 2.4 2 0 0 2 2 2 2 HMG-box domain Phe_tRNA-synt_N PF02912.18 RJW60262.1 - 0.021 14.8 0.5 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Latarcin PF10279.9 RJW60262.1 - 0.11 12.9 1.3 0.35 11.3 0.2 2.0 2 0 0 2 2 2 0 Latarcin precursor Ku_C PF03730.14 RJW60262.1 - 0.81 10.4 5.3 0.55 11.0 2.8 2.1 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm COX4 PF02936.14 RJW60262.1 - 0.87 9.6 5.6 2.3 8.2 0.5 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV UBX PF00789.20 RJW60265.1 - 2.9e-10 40.2 0.1 1.3e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 UBX domain Voldacs PF03517.13 RJW60265.1 - 0.011 15.8 0.4 0.04 14.1 0.4 1.9 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling FAM83 PF07894.12 RJW60265.1 - 8.2 5.9 5.9 15 5.1 5.9 1.3 1 0 0 1 1 1 0 FAM83 A-H Lig_chan PF00060.26 RJW60266.1 - 3.9e-11 43.0 0.0 6.5e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 Ligand-gated ion channel zf-C2H2 PF00096.26 RJW60267.1 - 1.2e-16 60.1 40.3 4.8e-05 23.6 0.3 7.0 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW60267.1 - 2.2e-13 50.0 45.7 4.6e-05 23.7 0.1 7.7 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW60267.1 - 2.4e-11 43.4 39.4 0.014 16.2 0.2 7.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW60267.1 - 0.014 15.4 33.0 0.11 12.6 1.3 5.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW60267.1 - 0.074 12.8 0.2 0.074 12.8 0.2 4.8 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-LYAR PF08790.11 RJW60267.1 - 0.23 11.4 0.1 0.23 11.4 0.1 3.8 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger DUF1075 PF06388.11 RJW60267.1 - 1.1 9.3 6.7 1.9 8.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) zf-met PF12874.7 RJW60267.1 - 1.8 9.1 19.2 13 6.3 0.6 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 RJW60267.1 - 4.6 7.4 20.5 16 5.7 0.1 5.5 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) IBR PF01485.21 RJW60267.1 - 4.9 7.5 21.6 1.7 8.9 1.2 4.2 3 1 1 4 4 4 0 IBR domain, a half RING-finger domain GpcrRhopsn4 PF10192.9 RJW60268.1 - 6.1e-28 97.9 18.0 1.5e-14 54.1 6.3 2.5 2 1 0 2 2 2 2 Rhodopsin-like GPCR transmembrane domain RVT_1 PF00078.27 RJW60269.1 - 5.3e-27 94.8 0.0 1e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGAP PF00620.27 RJW60270.1 - 2.2e-26 92.5 0.0 4.2e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DM PF00751.18 RJW60271.1 - 1.5e-29 101.6 31.6 9.2e-16 57.5 9.2 2.5 2 0 0 2 2 2 2 DM DNA binding domain zf-C3HC PF07967.13 RJW60271.1 - 0.14 12.2 10.9 0.66 10.0 1.2 3.4 3 0 0 3 3 3 0 C3HC zinc finger-like Tam41_Mmp37 PF09139.11 RJW60272.1 - 9e-70 235.6 0.0 1e-69 235.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Vault PF01505.18 RJW60274.1 - 9.6e-54 179.3 0.7 7.6e-15 54.8 0.0 5.3 5 1 1 6 6 6 4 Major Vault Protein repeat domain Vault_2 PF17794.1 RJW60274.1 - 1.2e-42 144.1 0.4 2.5e-28 98.2 0.1 2.8 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 RJW60274.1 - 4.9e-34 116.2 1.2 1.2e-30 105.3 0.0 4.4 4 0 0 4 4 4 1 Major Vault Protein Repeat domain MVP_shoulder PF11978.8 RJW60274.1 - 2.7e-33 114.5 0.0 4.7e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault_4 PF17796.1 RJW60274.1 - 3.4e-28 97.5 0.7 3.9e-25 87.7 0.2 4.5 5 0 0 5 5 5 1 Major Vault Protein repeat domain GCV_T PF01571.21 RJW60275.1 - 4.6e-75 252.3 0.0 6.3e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 RJW60275.1 - 5.3e-20 71.1 0.0 1.8e-19 69.4 0.0 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Vps26 PF03643.15 RJW60276.1 - 7.5e-66 221.9 0.0 4.4e-37 127.6 0.0 2.2 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 RVT_1 PF00078.27 RJW60276.1 - 3.1e-45 154.4 0.0 6.1e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Calcipressin PF04847.12 RJW60277.1 - 4.1e-23 82.1 1.6 7.2e-17 61.7 2.3 2.5 2 1 0 2 2 2 2 Calcipressin 4HBT_3 PF13622.6 RJW60279.1 - 1.2e-41 143.7 0.0 1.5e-41 143.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 RJW60279.1 - 1.1e-13 51.2 0.1 3e-08 33.6 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase EF-hand_7 PF13499.6 RJW60280.1 - 1.4e-11 44.7 1.8 0.00015 22.2 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RJW60280.1 - 8.7e-11 40.9 2.5 0.0011 18.7 0.2 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 RJW60280.1 - 1.1e-10 40.3 5.5 0.00019 20.7 0.1 4.3 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 RJW60280.1 - 1.8e-09 37.3 1.1 6.5e-06 25.9 0.0 3.8 3 1 1 4 4 4 2 EF-hand domain pair ribosomal_L24 PF17136.4 RJW60280.1 - 6.7e-06 26.4 0.0 2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 EF-hand_5 PF13202.6 RJW60280.1 - 4.3e-05 22.8 8.7 0.0029 17.0 0.1 4.2 5 0 0 5 5 5 2 EF hand KOW PF00467.29 RJW60280.1 - 0.0013 18.6 2.8 0.0013 18.6 2.8 1.9 2 0 0 2 2 2 1 KOW motif EF-hand_4 PF12763.7 RJW60280.1 - 0.0029 17.5 0.1 1.7 8.6 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 RJW60280.1 - 0.18 12.2 0.2 4.9 7.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Cytochrom_C1 PF02167.15 RJW60282.1 - 1e-92 309.8 0.0 1.2e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 RJW60282.1 - 4.9e-05 23.6 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 RJW60282.1 - 0.0027 18.8 0.2 0.0096 17.0 0.2 2.1 1 1 0 1 1 1 1 Cytochrome c NTP_transferase PF00483.23 RJW60284.1 - 6.3e-16 58.7 0.0 9.7e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 RJW60284.1 - 3.4e-07 29.7 8.2 1.9e-05 24.2 0.1 3.8 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Pyr_redox_2 PF07992.14 RJW60285.1 - 7.4e-56 189.5 0.0 1.1e-55 189.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RJW60285.1 - 3.7e-19 69.0 0.7 6.3e-14 52.2 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RJW60285.1 - 2e-16 60.3 0.4 2.4e-13 50.4 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RJW60285.1 - 3.2e-15 56.2 0.1 5.9e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RJW60285.1 - 5.3e-08 32.4 1.0 3.3e-06 26.5 1.1 2.5 2 1 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 RJW60285.1 - 4.5e-05 22.9 0.0 0.0046 16.3 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 RJW60285.1 - 0.0005 19.3 0.5 0.0011 18.1 0.5 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 RJW60285.1 - 0.0015 18.0 0.8 0.0022 17.4 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RJW60285.1 - 0.0054 15.5 0.3 0.011 14.5 0.3 1.5 1 0 0 1 1 1 1 HI0933-like protein K_oxygenase PF13434.6 RJW60285.1 - 0.015 14.4 0.0 0.83 8.7 0.0 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 RJW60285.1 - 0.031 13.5 0.1 0.07 12.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 RJW60285.1 - 1.9 8.8 4.7 2.8 8.2 0.8 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF1759 PF03564.15 RJW60287.1 - 6.5e-14 52.1 0.0 9.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Asp_protease_2 PF13650.6 RJW60287.1 - 0.005 17.4 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW60287.1 - 0.037 14.6 0.0 0.098 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Phytochelatin PF05023.14 RJW60288.1 - 1.8e-82 275.7 0.0 2.7e-82 275.1 0.0 1.3 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 RJW60288.1 - 0.043 14.4 0.1 13 6.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase_C39 like family Peptidase_C39 PF03412.15 RJW60288.1 - 0.12 12.2 0.0 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Peptidase C39 family Hema_stalk PF08720.10 RJW60288.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk Synaptobrevin PF00957.21 RJW60289.1 - 4.9e-26 90.3 5.1 5.4e-26 90.2 5.1 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 RJW60289.1 - 0.0087 16.2 0.4 0.0096 16.0 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF805 PF05656.14 RJW60289.1 - 0.092 13.2 0.9 0.11 12.9 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Integrase_H2C2 PF17921.1 RJW60289.1 - 0.11 12.6 0.9 0.22 11.7 0.9 1.4 1 0 0 1 1 1 0 Integrase zinc binding domain Dynein_light PF01221.18 RJW60290.1 - 9e-14 51.6 0.1 1.9e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_5 PF13202.6 RJW60290.1 - 1.7e-13 49.4 1.0 1.7e-05 24.1 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 RJW60290.1 - 2.6e-13 48.5 2.5 1.1e-05 24.6 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW60290.1 - 3.3e-12 46.7 4.2 3.7e-12 46.5 1.8 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW60290.1 - 7.9e-10 37.9 3.2 8.7e-05 22.2 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RJW60290.1 - 1.2e-06 28.8 0.3 1.2e-06 28.8 0.3 1.7 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 RJW60290.1 - 1.5e-05 24.7 0.9 3.5e-05 23.5 0.5 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.7 RJW60290.1 - 0.0072 16.3 1.2 0.011 15.7 0.3 1.7 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Fer4_12 PF13353.6 RJW60290.1 - 0.036 14.3 0.3 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Dockerin_1 PF00404.18 RJW60290.1 - 0.073 13.3 0.9 0.4 10.9 0.9 2.1 1 1 0 1 1 1 0 Dockerin type I domain bZIP_2 PF07716.15 RJW60291.1 - 5.1e-24 84.1 30.2 7.4e-16 58.0 10.1 2.5 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 RJW60291.1 - 1.5e-06 28.2 29.1 0.00029 20.9 9.9 2.7 2 0 0 2 2 2 2 bZIP transcription factor HALZ PF02183.18 RJW60291.1 - 0.51 10.6 3.9 22 5.4 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Laminin_G_2 PF02210.24 RJW60292.1 - 1e-05 26.1 0.0 2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 RJW60292.1 - 0.00066 19.9 0.0 0.58 10.4 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain C1q PF00386.21 RJW60295.1 - 7.1e-23 81.2 0.0 8.2e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 C1q domain PA14 PF07691.12 RJW60295.1 - 1.6e-05 24.7 0.0 3.3e-05 23.7 0.0 1.5 1 1 1 2 2 2 1 PA14 domain BclA_C PF18573.1 RJW60295.1 - 0.0079 16.1 0.0 0.0091 15.9 0.0 1.1 1 0 0 1 1 1 1 BclA C-terminal domain Ras PF00071.22 RJW60296.1 - 2.5e-52 176.7 0.0 2.9e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW60296.1 - 4.9e-21 75.2 0.0 6.8e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW60296.1 - 7.9e-07 28.7 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW60296.1 - 0.0024 17.3 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RJW60296.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1972 PF09314.11 RJW60296.1 - 0.093 12.3 0.0 0.29 10.7 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1972) G-alpha PF00503.20 RJW60296.1 - 0.2 10.8 0.1 1.3 8.1 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit AcetylCoA_hyd_C PF13336.6 RJW60299.1 - 2.6e-57 193.1 0.0 4.3e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 RJW60299.1 - 3.9e-20 72.7 0.0 7.8e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Linker_histone PF00538.19 RJW60300.1 - 2.7e-11 43.7 0.1 4.2e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family C1_1 PF00130.22 RJW60301.1 - 3.5e-09 36.4 28.0 1.8e-07 30.9 11.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_cat PF00781.24 RJW60301.1 - 0.00025 20.7 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RRM_1 PF00076.22 RJW60303.1 - 7.6e-17 60.9 0.0 2.9e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RJW60303.1 - 0.0037 17.3 0.0 0.084 12.9 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif Ras PF00071.22 RJW60304.1 - 2.1e-48 164.0 0.0 2.3e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW60304.1 - 2.7e-22 79.2 0.0 3.4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW60304.1 - 1.3e-07 31.2 0.0 2e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RJW60304.1 - 0.023 14.1 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RJW60304.1 - 0.049 13.0 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DLIC PF05783.11 RJW60304.1 - 0.2 10.4 0.1 0.93 8.2 0.1 1.8 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) zf-C3HC4 PF00097.25 RJW60306.1 - 3.3e-06 26.9 5.4 8.4e-06 25.6 5.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW60306.1 - 0.0046 16.9 9.7 0.016 15.2 9.7 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RJW60306.1 - 0.012 15.6 10.1 0.036 14.0 9.6 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RJW60306.1 - 0.016 15.1 11.5 0.033 14.0 11.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_prox PF18274.1 RJW60306.1 - 0.07 13.1 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe zf-RING_2 PF13639.6 RJW60306.1 - 0.079 13.3 12.8 0.31 11.4 12.8 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 RJW60306.1 - 0.15 11.9 9.3 0.056 13.3 5.3 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RJW60306.1 - 0.15 12.2 7.9 0.4 10.9 7.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ACC PF17848.1 RJW60309.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain LytR_cpsA_psr PF03816.14 RJW60309.1 - 0.23 11.6 0.5 0.44 10.7 0.5 1.4 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain DUF3421 PF11901.8 RJW60310.1 - 5.4e-31 107.0 0.1 1e-30 106.1 0.1 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3421) FYVE_2 PF02318.16 RJW60311.1 - 0.019 15.1 0.9 0.046 13.9 0.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DDE_Tnp_IS1595 PF12762.7 RJW60311.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 ISXO2-like transposase domain Glycos_transf_1 PF00534.20 RJW60313.1 - 1.1e-15 57.6 0.0 4.4e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RJW60313.1 - 5.6e-07 30.1 0.0 1.2e-06 29.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 RJW60313.1 - 0.005 17.2 0.0 0.009 16.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Leptin PF02024.15 RJW60313.1 - 0.046 13.5 0.1 0.072 12.9 0.1 1.2 1 0 0 1 1 1 0 Leptin PP2C PF00481.21 RJW60314.1 - 5.9e-11 42.5 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF1106 PF06523.11 RJW60314.1 - 0.16 12.0 0.0 28 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1106) STAR_dimer PF16544.5 RJW60317.1 - 2.3e-10 39.9 0.0 4.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 RJW60317.1 - 0.005 16.6 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 KH domain Fasciclin PF02469.22 RJW60318.1 - 2.3e-22 79.6 0.9 1.9e-10 41.0 0.0 4.4 4 1 0 4 4 4 4 Fasciclin domain Spectrin PF00435.21 RJW60319.1 - 4.8e-113 370.9 124.6 1.2e-14 54.7 3.0 18.9 18 2 0 18 18 18 17 Spectrin repeat CH PF00307.31 RJW60319.1 - 1.6e-31 108.7 0.1 9.2e-24 83.7 0.0 3.7 3 0 0 3 3 3 2 Calponin homology (CH) domain PH_9 PF15410.6 RJW60319.1 - 2.5e-16 60.1 0.0 8.3e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 RJW60319.1 - 1e-11 45.3 0.6 1.1e-10 42.0 0.0 3.2 4 0 0 4 4 4 1 PH domain CAMSAP_CH PF11971.8 RJW60319.1 - 2.1e-06 27.4 0.0 6.5e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain DUF2205 PF10224.9 RJW60321.1 - 3.7e-27 94.1 2.2 4.8e-27 93.8 2.2 1.2 1 0 0 1 1 1 1 Short coiled-coil protein KASH_CCD PF14662.6 RJW60321.1 - 0.0002 21.3 2.9 0.00022 21.1 2.9 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 RJW60321.1 - 0.0024 17.9 0.9 0.0048 17.0 0.5 1.8 1 1 1 2 2 2 1 bZIP transcription factor YabA PF06156.13 RJW60321.1 - 0.0026 18.4 1.5 0.0033 18.0 1.5 1.2 1 0 0 1 1 1 1 Initiation control protein YabA CENP-H PF05837.12 RJW60321.1 - 0.011 16.1 2.3 0.014 15.8 2.3 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HALZ PF02183.18 RJW60321.1 - 0.012 15.8 1.8 1.5 9.1 0.3 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 RJW60321.1 - 0.024 15.1 3.4 0.043 14.3 2.5 1.8 1 1 1 2 2 2 0 Cell division protein ZapB NRBF2 PF08961.10 RJW60321.1 - 0.026 14.1 0.6 0.03 13.9 0.6 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator NTP_transf_2 PF01909.23 RJW60321.1 - 0.11 12.8 0.1 0.14 12.5 0.1 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase domain Syntaxin-6_N PF09177.11 RJW60321.1 - 0.12 12.9 3.2 0.26 11.9 3.2 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Takusan PF04822.13 RJW60321.1 - 0.21 11.5 3.8 0.28 11.1 3.7 1.4 1 1 0 1 1 1 0 Takusan Dynein_light PF01221.18 RJW60323.1 - 9.8e-14 51.5 0.2 1.6e-13 50.8 0.2 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 Mgr1 PF08602.10 RJW60323.1 - 0.023 13.5 0.1 0.028 13.3 0.1 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit PhetRS_B1 PF18262.1 RJW60323.1 - 0.12 12.6 0.3 0.91 9.8 0.1 2.3 1 1 1 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Tektin PF03148.14 RJW60324.1 - 3e-114 381.7 37.5 3.7e-114 381.5 37.5 1.0 1 0 0 1 1 1 1 Tektin family CG-1 PF03859.16 RJW60324.1 - 0.085 12.6 1.0 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 CG-1 domain DUF1664 PF07889.12 RJW60324.1 - 2 8.5 25.7 0.16 12.1 1.6 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 RJW60324.1 - 2.6 7.8 25.5 0.098 12.5 5.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 RJW60324.1 - 7.3 7.1 15.8 0.1 13.0 2.2 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 RJW60324.1 - 8.3 3.8 36.5 0.21 9.1 9.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 RJW60324.1 - 8.5 6.4 19.0 0.53 10.3 0.2 3.8 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dynein_light PF01221.18 RJW60327.1 - 7.5e-16 58.2 0.0 1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 RJW60327.1 - 5.1e-10 39.7 2.0 5.5e-10 39.6 0.8 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW60327.1 - 1.8e-09 36.5 0.2 2.5e-05 23.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW60327.1 - 6.9e-08 31.8 1.0 0.0012 18.6 0.1 2.7 1 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RJW60327.1 - 1.6e-06 27.4 0.1 0.00045 19.6 0.0 2.5 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 RJW60327.1 - 3.6e-06 27.3 0.3 9.7e-06 25.9 0.2 1.7 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 RJW60327.1 - 6e-06 26.0 0.5 3.3e-05 23.6 0.3 2.1 1 1 1 2 2 2 1 EF-hand domain pair E2F_TDP PF02319.20 RJW60327.1 - 0.028 14.5 0.0 0.29 11.2 0.0 2.2 2 1 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain Dockerin_1 PF00404.18 RJW60327.1 - 0.46 10.7 2.2 2.5 8.4 2.2 2.1 1 1 0 1 1 1 0 Dockerin type I domain RVT_1 PF00078.27 RJW60328.1 - 0.063 12.8 0.0 9.2 5.7 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.7 RJW60329.1 - 2.1e-71 236.5 18.6 3.2e-17 62.9 0.2 8.7 5 3 4 9 9 9 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW60329.1 - 2.1e-70 231.8 24.7 5.4e-11 42.5 0.0 11.0 6 3 5 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW60329.1 - 1e-67 223.7 15.7 2.9e-11 43.6 0.1 11.5 6 2 5 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 RJW60329.1 - 3.4e-63 207.5 29.6 3.5e-06 27.2 0.0 13.3 13 0 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.6 RJW60329.1 - 7e-61 195.0 21.2 5.4e-05 23.3 0.0 15.1 16 0 0 16 16 16 10 Ankyrin repeat PARP PF00644.20 RJW60329.1 - 1.8e-23 83.2 1.8 1.5e-21 76.9 0.3 2.9 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain SAM_1 PF00536.30 RJW60329.1 - 3.1e-14 53.1 0.3 6.2e-14 52.2 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RJW60329.1 - 6.3e-11 42.2 0.1 1.3e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1843 PF08898.10 RJW60329.1 - 0.037 14.5 0.1 58 4.3 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) BRK PF07533.16 RJW60329.1 - 0.087 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 BRK domain Pkinase PF00069.25 RJW60330.1 - 2.1e-15 56.8 0.0 2.5e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60330.1 - 1.5e-07 31.0 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3256 PF11644.8 RJW60330.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Neuropeptide_S PF14993.6 RJW60330.1 - 0.063 13.1 0.0 0.32 10.9 0.0 2.1 3 0 0 3 3 3 0 Neuropeptide S precursor protein DSS1_SEM1 PF05160.13 RJW60332.1 - 1.2e-17 63.7 7.1 1.6e-17 63.3 7.1 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family FYVE PF01363.21 RJW60334.1 - 8.6e-19 67.5 11.9 1.5e-18 66.7 11.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 RJW60334.1 - 5.2e-06 26.9 0.0 1.6e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.16 RJW60334.1 - 0.00014 22.1 8.8 0.00029 21.1 8.8 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger IQ_SEC7_PH PF16453.5 RJW60334.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 RJW60334.1 - 0.0031 17.3 1.1 0.62 9.9 1.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Ndc1_Nup PF09531.10 RJW60334.1 - 0.41 9.3 2.5 0.56 8.8 2.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C2HC5 PF06221.13 RJW60334.1 - 1.4 9.0 13.2 5.2 7.1 13.2 1.9 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF2318 PF10080.9 RJW60334.1 - 7.8 6.7 8.5 3.7 7.7 2.9 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) DZR PF12773.7 RJW60334.1 - 8.3 6.5 11.8 40 4.3 2.7 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-piccolo PF05715.13 RJW60334.1 - 9.7 6.4 11.6 25 5.1 7.2 2.5 2 0 0 2 2 2 0 Piccolo Zn-finger DUF3700 PF12481.8 RJW60336.1 - 0.033 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein SET PF00856.28 RJW60337.1 - 2.7e-19 70.2 0.3 8.1e-19 68.6 0.1 2.0 2 0 0 2 2 2 1 SET domain AWS PF17907.1 RJW60337.1 - 1.4e-13 50.6 3.5 6.5e-13 48.5 3.5 2.2 1 0 0 1 1 1 1 AWS domain PHD PF00628.29 RJW60337.1 - 9.2e-11 41.5 51.1 2.8e-05 23.9 11.1 7.3 6 1 1 7 7 7 4 PHD-finger PWWP PF00855.17 RJW60337.1 - 6.2e-08 32.9 0.1 0.004 17.5 0.0 3.2 3 1 0 3 3 3 2 PWWP domain C5HCH PF17982.1 RJW60337.1 - 7.2e-08 32.5 8.2 7.2e-08 32.5 8.2 3.9 4 0 0 4 4 4 1 NSD Cys-His rich domain zf-HC5HC2H PF13771.6 RJW60337.1 - 0.022 15.0 30.2 0.022 15.0 0.1 5.7 5 1 0 5 5 5 0 PHD-like zinc-binding domain MFS_1 PF07690.16 RJW60339.1 - 2.2e-24 86.0 57.6 1.7e-18 66.7 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0060 PF02694.15 RJW60339.1 - 1.6 9.0 14.7 0.07 13.4 4.6 2.7 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DEAD PF00270.29 RJW60340.1 - 2.6e-46 157.6 0.9 5.2e-46 156.6 0.9 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW60340.1 - 4.5e-31 107.5 0.2 1.5e-30 105.8 0.1 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW60340.1 - 4e-07 30.2 0.0 7.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RJW60340.1 - 4.2e-06 27.2 0.9 6.5e-06 26.5 0.2 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RJW60340.1 - 6.7e-05 22.7 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW60340.1 - 0.001 19.3 0.5 0.0058 16.9 0.5 2.2 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 RJW60340.1 - 0.011 15.7 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 RJW60340.1 - 0.014 14.7 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 RJW60340.1 - 0.027 14.5 0.4 0.13 12.2 0.3 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Phage_integrase PF00589.22 RJW60340.1 - 0.039 13.8 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family DUF3419 PF11899.8 RJW60340.1 - 0.082 12.1 0.1 0.34 10.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3419) RVT_1 PF00078.27 RJW60341.1 - 0.0032 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Q_salvage PF10343.9 RJW60342.1 - 2.3e-92 309.6 0.0 4.4e-92 308.6 0.0 1.4 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family OCRE PF17780.1 RJW60342.1 - 6.7e-15 54.9 14.2 1.7e-14 53.6 14.2 1.7 1 0 0 1 1 1 1 OCRE domain G-patch PF01585.23 RJW60342.1 - 1.8e-14 53.3 2.8 1.8e-14 53.3 2.8 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 RJW60342.1 - 3.1e-07 30.4 1.1 6.8e-07 29.3 1.1 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 RJW60342.1 - 5.8e-06 26.0 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SART-1 PF03343.13 RJW60342.1 - 0.00035 19.3 0.1 0.00035 19.3 0.1 2.2 2 0 0 2 2 2 1 SART-1 family zf-C2H2_jaz PF12171.8 RJW60342.1 - 0.0099 16.1 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RED_N PF07808.13 RJW60342.1 - 2 8.0 8.0 0.041 13.5 0.8 1.8 2 0 0 2 2 2 0 RED-like protein N-terminal region ATP-grasp_2 PF08442.10 RJW60343.1 - 1.6e-68 230.3 0.9 2.4e-68 229.7 0.9 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 RJW60343.1 - 3.5e-21 75.6 1.6 4.1e-21 75.4 0.1 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 RJW60343.1 - 7.7e-05 22.2 0.1 0.00016 21.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 RJW60343.1 - 0.0019 18.0 0.1 0.0095 15.7 0.0 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 RJW60343.1 - 0.0025 17.6 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Cnd1 PF12717.7 RJW60344.1 - 0.051 13.6 0.3 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 tRNA-synt_1b PF00579.25 RJW60345.1 - 3.3e-22 79.2 0.0 3.9e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) fn3 PF00041.21 RJW60346.1 - 2.2e-06 27.9 8.9 0.00033 21.0 0.9 5.4 5 1 0 5 5 5 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW60346.1 - 3.8e-05 24.2 5.5 5.5 7.6 5.5 5.5 4 1 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain DAAD PF18752.1 RJW60346.1 - 0.069 13.0 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase KH_1 PF00013.29 RJW60347.1 - 8.7e-09 35.1 0.3 2.2e-08 33.8 0.3 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 RJW60347.1 - 0.00024 20.9 0.0 0.00055 19.8 0.0 1.5 1 0 0 1 1 1 1 KH domain PA26 PF04636.13 RJW60347.1 - 1.4 7.8 6.1 2.5 6.9 6.1 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) eIF3_subunit PF08597.10 RJW60347.1 - 4.1 7.2 17.4 3 7.7 1.6 3.1 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit LRR_4 PF12799.7 RJW60348.1 - 0.16 12.4 15.1 12 6.5 0.8 6.1 3 2 4 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW60348.1 - 2.5 8.0 11.5 5.4 6.8 1.1 4.9 4 1 1 5 5 5 0 Leucine rich repeat FAD_binding_3 PF01494.19 RJW60349.1 - 0.15 11.3 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain fn3 PF00041.21 RJW60350.1 - 0.0062 16.9 8.7 4.2 7.8 0.1 5.1 5 1 0 5 5 5 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW60350.1 - 0.0083 16.7 11.2 4.1 8.0 1.4 4.9 5 1 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Mito_carr PF00153.27 RJW60351.1 - 3e-61 203.4 0.9 1.1e-22 79.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C3HC4_3 PF13920.6 RJW60352.1 - 0.13 12.1 1.7 0.24 11.3 1.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4796 PF16044.5 RJW60352.1 - 0.16 11.6 0.3 0.38 10.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) tRNA-synt_1d PF00750.19 RJW60354.1 - 1.5e-61 208.3 0.0 3e-61 207.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 RJW60354.1 - 8.3e-16 58.2 0.0 3e-14 53.2 0.0 2.5 1 1 0 1 1 1 1 DALR anticodon binding domain Toxin_18 PF08087.11 RJW60355.1 - 0.096 12.7 2.3 0.3 11.1 2.3 1.8 2 0 0 2 2 2 0 Conotoxin O-superfamily RT_RNaseH_2 PF17919.1 RJW60357.1 - 2e-05 24.6 0.0 3.5e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW60357.1 - 0.00012 22.3 0.1 0.00078 19.7 0.1 2.0 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HMG_box PF00505.19 RJW60358.1 - 1.9e-10 41.0 0.2 4.3e-09 36.7 0.1 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box Tubulin PF00091.25 RJW60359.1 - 5.4e-41 141.0 0.0 5.8e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 RJW60359.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Tubulin like Phage_P2_GpE PF06528.12 RJW60360.1 - 0.16 11.6 0.1 0.36 10.4 0.1 1.6 1 0 0 1 1 1 0 Phage P2 GpE Phosphodiest PF01663.22 RJW60362.1 - 3.2e-12 46.7 1.9 5.8e-07 29.4 0.3 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RJW60362.1 - 0.0001 21.8 0.1 0.00089 18.7 0.0 2.3 2 1 1 3 3 3 1 Sulfatase Metalloenzyme PF01676.18 RJW60362.1 - 0.0051 16.2 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily ERM PF00769.19 RJW60363.1 - 3.9e-19 69.5 46.1 7.6e-19 68.5 4.0 2.2 1 1 1 2 2 2 2 Ezrin/radixin/moesin family FERM_C PF09380.10 RJW60363.1 - 3.4e-15 56.2 0.0 6.7e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RJW60363.1 - 1.5e-08 35.0 0.1 1.5e-08 35.0 0.1 2.4 2 1 0 2 2 2 1 FERM central domain Tweety PF04906.13 RJW60363.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Tweety Cauli_AT PF03233.13 RJW60363.1 - 0.14 12.1 2.4 0.29 11.1 2.4 1.5 1 0 0 1 1 1 0 Aphid transmission protein FapA PF03961.13 RJW60363.1 - 8.3 4.9 11.1 13 4.2 11.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ank_2 PF12796.7 RJW60364.1 - 7.9e-155 503.9 43.2 8.9e-19 67.9 0.0 13.4 2 2 11 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.30 RJW60364.1 - 9.6e-121 389.5 43.5 1.1e-06 28.9 0.0 25.2 25 0 0 25 25 25 22 Ankyrin repeat Ank_4 PF13637.6 RJW60364.1 - 2.5e-114 372.3 18.8 4e-11 43.2 0.0 16.1 7 3 11 19 19 19 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW60364.1 - 6.7e-114 357.9 29.5 7e-05 22.9 0.0 25.2 25 0 0 25 25 25 23 Ankyrin repeat Ank_5 PF13857.6 RJW60364.1 - 1.8e-94 308.6 44.4 2.5e-07 30.8 0.3 22.1 6 5 18 24 24 24 23 Ankyrin repeats (many copies) DUF295 PF03478.18 RJW60366.1 - 0.046 13.3 0.5 0.12 11.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF295) Pex24p PF06398.11 RJW60367.1 - 0.81 8.6 4.3 0.82 8.6 4.3 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF1700 PF08006.11 RJW60367.1 - 2.5 7.6 18.6 3.3 7.2 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF2207 PF09972.9 RJW60367.1 - 4.4 6.0 11.7 4.8 5.8 11.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PocR PF10114.9 RJW60371.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR Gtr1_RagA PF04670.12 RJW60372.1 - 9.2e-46 156.1 3.3 9.2e-46 156.1 3.3 1.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.21 RJW60372.1 - 0.00015 21.3 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RJW60372.1 - 0.021 15.0 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Csm1_B PF18211.1 RJW60372.1 - 0.21 11.5 0.9 1.2 9.0 0.0 2.6 4 0 0 4 4 4 0 Csm1 subunit domain B CUB PF00431.20 RJW60374.1 - 2.3e-18 66.5 0.0 9.2e-18 64.6 0.0 2.0 2 0 0 2 2 2 1 CUB domain Ldl_recept_a PF00057.18 RJW60374.1 - 0.0085 16.3 7.4 0.019 15.2 7.4 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A fn3 PF00041.21 RJW60376.1 - 1.7e-11 44.3 9.3 0.014 15.7 0.1 7.7 8 0 0 8 8 8 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW60376.1 - 3.2e-05 24.4 11.5 0.41 11.3 0.2 7.4 8 0 0 8 8 8 1 Purple acid Phosphatase, N-terminal domain VID27_PH PF17747.1 RJW60376.1 - 0.099 12.9 0.2 8 6.8 0.0 3.5 3 0 0 3 3 3 0 VID27 PH-like domain RGI_lyase PF18370.1 RJW60376.1 - 1.5 9.2 4.0 45 4.4 0.0 4.4 4 0 0 4 4 4 0 Rhamnogalacturonan I lyases beta-sheet domain Histone PF00125.24 RJW60379.1 - 1.7e-32 112.5 2.2 1.7e-32 112.5 2.2 1.7 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 IMD PF08397.11 RJW60381.1 - 1.6e-33 115.9 0.1 2.5e-31 108.8 0.1 2.2 1 1 0 1 1 1 1 IRSp53/MIM homology domain Pkinase_Tyr PF07714.17 RJW60382.1 - 1.5e-87 293.2 0.0 1.8e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW60382.1 - 3e-45 154.7 0.0 4e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RJW60382.1 - 1.9e-06 27.9 0.4 4e-06 26.8 0.4 1.6 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 RJW60382.1 - 0.011 15.6 0.1 0.03 14.2 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW60382.1 - 0.012 14.6 0.0 0.026 13.5 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RJW60382.1 - 0.014 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FERM_C PF09380.10 RJW60383.1 - 5.7e-20 71.5 0.0 1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RJW60383.1 - 4.9e-18 65.6 0.0 4.9e-18 65.6 0.0 2.1 3 0 0 3 3 3 1 FERM central domain FERM_N PF09379.10 RJW60383.1 - 1.6e-17 63.1 0.1 3.4e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 RJW60383.1 - 0.034 14.2 0.4 0.034 14.2 0.4 3.5 3 0 0 3 3 3 0 FERM adjacent (FA) Sulfotransfer_3 PF13469.6 RJW60384.1 - 2.2e-28 100.1 0.0 3.6e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RJW60384.1 - 1.7e-08 34.3 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain URO-D PF01208.17 RJW60385.1 - 3.3e-125 417.8 0.0 3.9e-125 417.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) RVT_1 PF00078.27 RJW60388.1 - 4.4e-07 29.6 0.0 6.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NIF PF03031.18 RJW60389.1 - 3e-48 163.5 0.0 3.8e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1850 PF08905.11 RJW60389.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) ADK PF00406.22 RJW60390.1 - 7.3e-09 35.9 0.0 7.6e-05 22.9 0.0 3.0 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 RJW60390.1 - 4.4e-08 33.6 0.1 0.0012 19.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RJW60390.1 - 0.00019 22.0 0.0 0.0041 17.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RJW60390.1 - 0.00033 21.1 0.0 0.00088 19.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW60390.1 - 0.00036 21.0 1.3 0.0017 18.8 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 RJW60390.1 - 0.00048 20.3 0.0 0.033 14.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain Glycos_transf_2 PF00535.26 RJW60390.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Hydin_ADK PF17213.3 RJW60390.1 - 0.0096 16.2 0.2 0.03 14.6 0.0 2.0 2 1 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 RJW60390.1 - 0.012 15.8 0.3 0.16 12.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 RJW60390.1 - 0.017 14.9 0.0 0.044 13.5 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 RJW60390.1 - 0.022 14.8 0.0 0.083 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 RJW60390.1 - 0.025 14.8 0.2 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RJW60390.1 - 0.036 13.8 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RJW60390.1 - 0.072 13.0 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 RJW60390.1 - 0.12 12.4 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 RJW60390.1 - 0.14 11.3 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 RJW60390.1 - 0.14 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 RJW60390.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 RJW60392.1 - 1.4e-87 293.5 0.0 2.7e-87 292.6 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 RJW60392.1 - 1.7e-05 24.9 0.0 4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FapA PF03961.13 RJW60392.1 - 2.5e-05 23.1 0.7 4.1e-05 22.4 0.7 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A Fez1 PF06818.15 RJW60392.1 - 4.8e-05 23.9 13.9 0.0001 22.8 13.9 1.4 1 0 0 1 1 1 1 Fez1 FtsK_SpoIIIE PF01580.18 RJW60392.1 - 0.0058 16.0 2.1 0.0062 15.9 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family FAM184 PF15665.5 RJW60392.1 - 0.011 15.5 12.2 0.025 14.4 12.2 1.5 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Dynamin_N PF00350.23 RJW60392.1 - 0.03 14.4 2.6 1.5 8.8 0.0 3.3 3 0 0 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 RJW60392.1 - 0.063 13.2 1.0 0.73 9.7 0.2 2.7 2 1 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 RJW60392.1 - 0.093 12.6 0.1 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 NTPase RIB43A PF05914.12 RJW60392.1 - 0.099 11.4 16.7 0.17 10.6 16.7 1.3 1 0 0 1 1 1 0 RIB43A Exonuc_VII_L PF02601.15 RJW60392.1 - 0.13 11.8 3.3 0.2 11.2 3.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MeaB PF03308.16 RJW60392.1 - 0.15 11.0 0.0 0.15 11.0 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 RJW60392.1 - 0.16 11.2 0.0 0.16 11.2 0.0 2.4 3 0 0 3 3 3 0 AIG1 family AAA_22 PF13401.6 RJW60392.1 - 0.2 12.0 0.4 1.3 9.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 RJW60392.1 - 0.43 10.9 2.3 0.48 10.8 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain UPF0242 PF06785.11 RJW60392.1 - 0.9 9.6 15.5 1.8 8.6 12.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1043 PF06295.12 RJW60392.1 - 3.1 7.8 6.4 7.5 6.6 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Ras PF00071.22 RJW60393.1 - 3.2e-23 82.1 0.0 3.8e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.21 RJW60393.1 - 1e-08 34.8 0.0 1.2e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RJW60393.1 - 2.3e-08 34.3 0.0 1.1e-07 32.1 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 RJW60393.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Colicin PF01024.19 RJW60394.1 - 0.015 15.2 0.4 0.019 14.9 0.4 1.1 1 0 0 1 1 1 0 Colicin pore forming domain PH PF00169.29 RJW60395.1 - 5e-06 27.0 0.0 2.8e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 RJW60395.1 - 0.013 15.9 0.0 0.064 13.7 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3362 PF11842.8 RJW60395.1 - 0.1 12.9 0.3 0.29 11.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) FUSC-like PF12805.7 RJW60397.1 - 0.22 10.6 0.3 5.4 6.0 0.0 2.2 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS RVT_1 PF00078.27 RJW60398.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C1 PF00112.23 RJW60400.1 - 2.1e-61 207.8 3.3 2.6e-61 207.5 3.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 RJW60400.1 - 8.7e-11 41.5 0.0 1.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 RJW60400.1 - 0.0016 17.3 0.4 1 8.1 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family PMI_typeI PF01238.21 RJW60402.1 - 7.1e-88 295.3 0.0 9.5e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Ribosomal_L13e PF01294.18 RJW60403.1 - 1.1e-73 247.0 8.2 1.3e-73 246.7 8.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e RNA_pol_A_bac PF01000.26 RJW60404.1 - 1.5e-32 112.3 0.0 2.4e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 RJW60404.1 - 1.7e-18 65.8 0.0 2.3e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain rpo30_N PF12410.8 RJW60404.1 - 0.063 13.2 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit TBP PF00352.21 RJW60405.1 - 1.5e-61 204.3 0.1 3.3e-30 103.9 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 RJW60405.1 - 0.0028 17.7 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) RGS PF00615.19 RJW60406.1 - 1.3e-33 115.8 4.1 1.7e-33 115.4 4.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 RJW60406.1 - 0.022 14.5 0.3 0.031 14.0 0.3 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Kinesin PF00225.23 RJW60407.1 - 1.2e-107 359.7 0.1 2.1e-107 358.9 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 RJW60407.1 - 9.1e-45 153.0 9.8 2.1e-35 122.5 1.6 3.0 2 1 1 3 3 3 2 Kinesin-associated DUF3694 PF12473.8 RJW60407.1 - 5.4e-38 131.1 0.0 1.8e-37 129.4 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 RJW60407.1 - 1.1e-17 64.3 0.0 3.1e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding DCR PF14047.6 RJW60407.1 - 0.068 13.4 0.0 0.85 9.9 0.0 2.4 2 0 0 2 2 2 0 Dppa2/4 conserved region L_HMGIC_fpl PF10242.9 RJW60409.1 - 2.2e-05 24.8 1.0 3.9e-05 23.9 1.0 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Acp26Ab PF05777.12 RJW60409.1 - 4 8.1 9.4 3.5 8.3 0.1 2.9 3 0 0 3 3 3 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) TatD_DNase PF01026.21 RJW60412.1 - 3.4e-28 98.7 0.0 3.9e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF2315 PF10231.9 RJW60414.1 - 1.9e-22 79.6 1.1 3.5e-22 78.8 1.1 1.4 1 0 0 1 1 1 1 Apoptogenic protein 1 TatD_DNase PF01026.21 RJW60415.1 - 1.8e-20 73.4 0.0 2.2e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 RJW60415.1 - 0.018 14.9 0.0 0.019 14.8 0.0 1.0 1 0 0 1 1 1 0 Amidohydrolase Plectin PF00681.20 RJW60416.1 - 0.018 14.9 0.0 1.9 8.4 0.0 3.1 3 0 0 3 3 3 0 Plectin repeat NADHdh_A3 PF14987.6 RJW60416.1 - 0.17 12.2 0.2 0.45 10.8 0.2 1.7 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DUF543 PF04418.12 RJW60417.1 - 3.8e-21 74.8 0.0 4.9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Integrase_H2C2 PF17921.1 RJW60419.1 - 0.00041 20.4 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Hydrolase_4 PF12146.8 RJW60420.1 - 2e-14 53.5 0.1 7.6e-09 35.2 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RJW60420.1 - 1.2e-11 44.8 0.4 1e-06 28.6 0.4 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RJW60420.1 - 8.3e-09 36.4 0.0 2.2e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RJW60420.1 - 1.1e-06 28.3 0.0 0.03 13.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 RJW60420.1 - 0.00037 20.4 0.0 0.0016 18.3 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 RJW60420.1 - 0.0076 16.4 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Luciferase_cat PF10285.9 RJW60420.1 - 0.038 13.4 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Luciferase catalytic domain Peptidase_S15 PF02129.18 RJW60420.1 - 0.043 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 RJW60420.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family RAP PF08373.10 RJW60420.1 - 0.13 12.4 0.2 0.3 11.2 0.2 1.6 1 0 0 1 1 1 0 RAP domain Ion_trans PF00520.31 RJW60423.1 - 2.6e-99 331.4 31.5 7.5e-65 218.6 18.5 2.1 2 0 0 2 2 2 2 Ion transport protein GPHH PF16905.5 RJW60423.1 - 5.2e-31 106.2 0.1 1e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 RJW60423.1 - 1.7e-28 98.7 0.1 3.5e-28 97.6 0.1 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.12 RJW60423.1 - 3.1e-06 26.1 9.9 3.1e-06 26.1 9.9 4.2 3 1 1 4 4 4 3 Polycystin cation channel Sigma_reg_N PF13800.6 RJW60423.1 - 7.4 6.9 12.0 5.5 7.3 0.8 3.9 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF2207 PF09972.9 RJW60423.1 - 7.7 5.1 7.0 2.5 6.7 0.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Tweety PF04906.13 RJW60425.1 - 0.001 17.8 0.1 0.0015 17.3 0.1 1.2 1 0 0 1 1 1 1 Tweety Ion_trans PF00520.31 RJW60426.1 - 7.7e-89 297.1 38.0 4e-64 216.2 6.5 3.7 2 1 0 2 2 2 2 Ion transport protein NHR2 PF08788.11 RJW60426.1 - 0.14 11.9 0.8 0.72 9.7 0.7 2.2 2 0 0 2 2 2 0 NHR2 domain like DUF3341 PF11821.8 RJW60426.1 - 0.57 9.8 3.4 3.2 7.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) DUF2207 PF09972.9 RJW60426.1 - 8.5 5.0 7.4 1 8.0 0.0 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4378 PF14309.6 RJW60427.1 - 0.039 14.3 0.4 0.25 11.7 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4378) zf-C4 PF00105.18 RJW60430.1 - 2.7e-16 59.8 7.3 3e-08 34.0 1.4 2.5 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Pkinase PF00069.25 RJW60432.1 - 1.4e-43 149.2 0.0 1.6e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60432.1 - 1.3e-22 80.3 0.0 1.5e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RJW60432.1 - 2.2e-06 27.2 0.0 3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RJW60432.1 - 0.002 17.5 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RJW60432.1 - 0.003 17.2 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RJW60432.1 - 0.0031 17.5 0.2 0.015 15.3 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW60432.1 - 0.0032 16.5 0.0 0.0038 16.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 RJW60432.1 - 0.15 11.7 0.0 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_A17 PF05380.13 RJW60434.1 - 1e-12 48.4 0.0 2.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase Asp_protease_2 PF13650.6 RJW60434.1 - 0.0015 19.1 0.0 0.0032 18.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 RJW60434.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 RJW60434.1 - 0.035 14.7 0.0 0.096 13.3 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease IRF PF00605.17 RJW60435.1 - 3.6e-38 130.1 1.0 7.1e-38 129.1 1.0 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.9 RJW60435.1 - 6.5e-26 91.2 0.0 1.2e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Interferon-regulatory factor 3 MH2 PF03166.14 RJW60435.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 MH2 domain Phytoreo_Pns PF05451.11 RJW60435.1 - 0.029 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 IQ PF00612.27 RJW60436.1 - 0.00072 19.1 0.2 0.0026 17.4 0.2 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3918 PF13056.6 RJW60436.1 - 0.31 10.7 1.0 0.73 9.5 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Cadherin_C PF01049.17 RJW60439.1 - 0.38 11.1 4.7 1.4 9.2 0.1 3.1 3 0 0 3 3 3 0 Cadherin cytoplasmic region p53-inducible11 PF14936.6 RJW60440.1 - 3e-06 27.4 0.2 8.7e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Tumour protein p53-inducible protein 11 UVR PF02151.19 RJW60441.1 - 3e-11 42.7 7.5 1.5e-06 27.7 0.8 2.8 2 0 0 2 2 2 2 UvrB/uvrC motif zf-TFIIIC PF12660.7 RJW60441.1 - 0.021 14.7 1.2 0.87 9.6 1.2 2.7 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex zf_UBZ PF18439.1 RJW60441.1 - 0.066 12.8 7.9 0.26 10.9 0.6 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger HEAT PF02985.22 RJW60441.1 - 0.17 12.2 0.2 7.3 7.1 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat Com_YlbF PF06133.11 RJW60441.1 - 2.1 9.0 7.2 0.17 12.5 1.7 2.0 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Ion_trans PF00520.31 RJW60444.1 - 1.7e-17 63.5 1.2 2.2e-17 63.1 1.2 1.2 1 0 0 1 1 1 1 Ion transport protein Heliorhodopsin PF18761.1 RJW60445.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Heliorhodopsin zf-C4 PF00105.18 RJW60446.1 - 8.6e-06 26.1 3.1 1.7e-05 25.2 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 RJW60446.1 - 0.00024 21.3 0.2 0.00043 20.5 0.2 1.4 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 RJW60446.1 - 0.006 16.4 5.7 0.0071 16.2 2.6 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 RJW60446.1 - 0.0074 16.2 0.9 4.5 7.3 0.8 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 DZR PF12773.7 RJW60446.1 - 0.035 14.1 1.4 0.081 13.0 1.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon WD40 PF00400.32 RJW60447.1 - 1.4e-31 108.0 13.2 1.6e-06 28.8 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW60447.1 - 4.3e-10 39.7 2.3 0.0024 18.1 0.0 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW60447.1 - 5.6e-06 26.4 0.3 9.6e-05 22.3 0.1 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Hormone_recep PF00104.30 RJW60448.1 - 1.8e-09 37.5 0.1 2.8e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C2H2_4 PF13894.6 RJW60451.1 - 0.1 13.5 6.5 0.49 11.4 1.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW60451.1 - 0.12 12.4 3.9 4.8 7.3 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW60451.1 - 0.28 11.7 10.2 0.37 11.4 3.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 RJW60451.1 - 1.4 9.4 0.1 1.4 9.4 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF2746 PF10874.8 RJW60453.1 - 0.092 13.2 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) zf-C2H2_4 PF13894.6 RJW60454.1 - 0.00019 22.0 8.0 0.016 16.0 0.7 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW60454.1 - 0.0005 20.4 0.4 0.0005 20.4 0.4 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.7 RJW60454.1 - 0.0011 19.3 2.5 0.074 13.5 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 RJW60454.1 - 0.011 15.3 2.0 0.15 11.7 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger CEBP_ZZ PF16366.5 RJW60454.1 - 0.092 13.0 5.8 0.24 11.7 5.8 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C2H2_6 PF13912.6 RJW60454.1 - 0.11 12.5 2.6 0.26 11.4 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger POP1 PF06978.11 RJW60455.1 - 1.1e-29 103.9 13.6 1.7e-18 67.4 0.2 2.2 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 RJW60455.1 - 9.3e-10 38.7 0.1 2.8e-09 37.2 0.1 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 RJW60455.1 - 0.044 13.1 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 RJW60455.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain HECT PF00632.25 RJW60456.1 - 3.5e-89 299.3 0.0 5.1e-89 298.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 RJW60456.1 - 2e-20 72.7 4.0 4.3e-20 71.7 4.0 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A GHL5 PF14872.6 RJW60457.1 - 0.096 10.7 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 MH2 PF03166.14 RJW60458.1 - 4.3e-21 76.0 0.0 5.5e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 MH2 domain MH1 PF03165.16 RJW60458.1 - 4.6e-11 42.8 1.4 1.1e-10 41.6 1.4 1.6 1 0 0 1 1 1 1 MH1 domain NYD-SP28 PF14772.6 RJW60459.1 - 1.9e-21 76.0 12.5 1.9e-21 76.0 12.5 5.2 5 2 1 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 RJW60459.1 - 0.00013 22.0 1.1 0.00013 22.0 1.1 4.9 4 1 0 4 4 4 1 Sperm tail C-terminal domain MCPsignal PF00015.21 RJW60459.1 - 0.092 12.6 2.2 2 8.2 0.5 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_16 PF13191.6 RJW60459.1 - 2 8.8 8.2 2.6 8.4 4.0 2.9 2 2 0 2 2 2 0 AAA ATPase domain Prismane PF03063.20 RJW60459.1 - 2.7 6.6 16.4 0.46 9.1 8.4 2.6 1 1 2 3 3 3 0 Prismane/CO dehydrogenase family Lectin_N PF03954.14 RJW60459.1 - 2.8 7.7 28.6 0.87 9.3 3.1 4.7 1 1 4 5 5 5 0 Hepatic lectin, N-terminal domain Plk4_PB2 PF18409.1 RJW60459.1 - 7.7 7.3 16.6 0.18 12.5 4.6 3.8 1 1 2 4 4 4 0 Polo-like Kinase 4 Polo Box 2 NIF PF03031.18 RJW60461.1 - 1.5e-38 132.1 0.1 2.2e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_transf_18 PF15024.6 RJW60463.1 - 2.9e-134 448.7 0.0 8.9e-126 420.7 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 18 Ribosomal_L16 PF00252.18 RJW60464.1 - 1e-24 87.0 0.0 1.5e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Frizzled PF01534.17 RJW60465.1 - 3.9e-115 384.4 19.3 5.5e-115 383.9 19.3 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 RJW60465.1 - 2.2e-33 115.2 6.1 2.2e-33 115.2 6.1 2.1 2 0 0 2 2 2 1 Fz domain Pkinase PF00069.25 RJW60468.1 - 2.8e-60 203.9 0.0 4.3e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60468.1 - 3.8e-30 105.1 0.0 5.8e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW60468.1 - 0.00016 21.1 0.0 0.00037 19.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW60468.1 - 0.045 12.7 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RJW60468.1 - 0.15 11.4 0.1 0.61 9.4 0.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTB PF00651.31 RJW60470.1 - 1.3e-26 93.0 0.0 5.5e-26 91.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 RJW60470.1 - 0.0035 17.4 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ig_3 PF13927.6 RJW60471.1 - 7e-18 65.0 0.0 3.2e-13 50.1 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RJW60471.1 - 5.2e-14 52.1 0.0 2.5e-10 40.3 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW60471.1 - 3.6e-11 43.2 0.0 4.2e-08 33.4 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RJW60471.1 - 5e-09 36.2 0.0 1.8e-07 31.3 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin domain RVT_1 PF00078.27 RJW60471.1 - 8.8e-07 28.7 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-set PF07686.17 RJW60471.1 - 0.00017 21.7 0.5 3.4 7.9 0.0 3.4 2 1 1 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 RJW60471.1 - 0.032 14.3 0.3 2 8.6 0.0 3.2 4 0 0 4 4 4 0 CD80-like C2-set immunoglobulin domain SNF2_N PF00176.23 RJW60472.1 - 2.5e-58 197.5 0.0 5.4e-58 196.4 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW60472.1 - 1.1e-16 61.2 0.0 2.5e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RJW60472.1 - 8.9e-11 41.5 0.0 3.9e-10 39.4 0.0 1.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 RJW60472.1 - 9.4e-11 42.0 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RJW60472.1 - 2.2e-05 24.3 0.0 4.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 RJW60472.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 RJW60472.1 - 0.11 12.8 0.1 1.4 9.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain RVT_1 PF00078.27 RJW60473.1 - 2.8e-45 154.6 0.0 4.8e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW60473.1 - 0.00015 21.4 0.8 0.00033 20.2 0.8 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PHO4 PF01384.20 RJW60474.1 - 2.8e-125 417.8 5.1 3.5e-125 417.5 5.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family RVT_1 PF00078.27 RJW60475.1 - 6e-05 22.7 0.0 0.00019 21.1 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) XkdW PF09636.10 RJW60475.1 - 1 9.5 6.6 1.1 9.4 0.6 3.3 2 0 0 2 2 2 0 XkdW protein DUF4381 PF14316.6 RJW60476.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Tmemb_55A PF09788.9 RJW60476.1 - 3 6.9 4.2 3.6 6.6 0.3 2.8 3 0 0 3 3 3 0 Transmembrane protein 55A SUR7 PF06687.12 RJW60477.1 - 0.23 11.1 2.2 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 SUR7/PalI family BOP1NT PF08145.12 RJW60478.1 - 1.9e-54 185.3 1.5 1.9e-54 185.3 1.5 2.7 2 1 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 RJW60478.1 - 2.6e-14 53.4 1.1 8.4e-06 26.4 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Melibiase_C PF17801.1 RJW60478.1 - 0.0023 18.0 0.0 0.55 10.3 0.0 3.1 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain 14-3-3 PF00244.20 RJW60479.1 - 1.8e-92 308.8 0.8 2.1e-92 308.6 0.8 1.0 1 0 0 1 1 1 1 14-3-3 protein FapA PF03961.13 RJW60479.1 - 0.036 12.7 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Talin_middle PF09141.10 RJW60481.1 - 2.2e-24 86.3 4.5 2.2e-24 86.3 4.5 13.4 10 4 3 14 14 14 2 Talin, middle domain I_LWEQ PF01608.17 RJW60481.1 - 1e-23 84.3 103.2 8.5e-08 32.6 4.6 15.4 10 4 4 15 15 15 7 I/LWEQ domain VBS PF08913.10 RJW60481.1 - 2.2e-10 41.0 46.4 9e-10 39.1 0.3 9.7 10 1 1 11 11 11 4 Vinculin Binding Site CLZ PF16526.5 RJW60481.1 - 0.0062 16.9 1.9 8.3 6.8 0.1 4.6 3 0 0 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snapin_Pallidin PF14712.6 RJW60481.1 - 0.016 15.6 15.9 0.021 15.3 0.2 6.8 7 0 0 7 7 7 0 Snapin/Pallidin Focal_AT PF03623.13 RJW60481.1 - 0.016 15.2 4.7 0.98 9.4 0.0 6.2 8 0 0 8 8 8 0 Focal adhesion targeting region SipA_VBS PF17985.1 RJW60481.1 - 0.057 13.3 0.3 3.1 7.9 0.0 3.9 4 0 0 4 4 4 0 SipA vinculin binding site Mer2 PF09074.10 RJW60481.1 - 0.29 10.9 2.5 1.8 8.4 0.2 3.6 5 0 0 5 5 5 0 Mer2 TRPM_tetra PF16519.5 RJW60481.1 - 1.9 8.7 4.2 27 5.0 0.1 2.9 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF2054 PF10218.9 RJW60483.1 - 5.5e-36 123.6 17.1 6.7e-36 123.3 17.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) Toxin_TOLIP PF00087.21 RJW60484.1 - 0.031 14.5 14.9 0.066 13.5 14.9 1.6 1 1 0 1 1 1 0 Snake toxin and toxin-like protein GIY-YIG PF01541.24 RJW60486.1 - 0.007 16.6 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Phage_T4_Ndd PF06591.11 RJW60487.1 - 0.084 12.7 0.7 2.5 7.9 0.1 2.2 1 1 1 2 2 2 0 T4-like phage nuclear disruption protein (Ndd) DUF4278 PF14105.6 RJW60488.1 - 0.13 12.7 0.0 0.19 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4278) Kelch_1 PF01344.25 RJW60491.1 - 2.2e-43 145.6 6.7 5.4e-11 41.9 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RJW60491.1 - 7.4e-33 111.8 5.8 6.2e-07 29.5 0.0 5.9 2 1 4 6 6 6 4 Kelch motif Kelch_2 PF07646.15 RJW60491.1 - 2.1e-22 78.2 2.0 8e-05 22.5 0.0 5.6 4 1 1 5 5 5 5 Kelch motif Kelch_4 PF13418.6 RJW60491.1 - 1.1e-15 57.3 2.0 8.5e-05 22.5 0.0 4.9 5 1 0 5 5 5 3 Galactose oxidase, central domain BACK PF07707.15 RJW60491.1 - 1e-14 54.5 1.1 1.7e-14 53.8 1.1 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 RJW60491.1 - 1.3e-10 41.2 1.8 0.026 14.8 0.1 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW60491.1 - 4.1e-07 29.8 7.1 0.29 11.2 0.0 4.6 4 0 0 4 4 4 3 Kelch motif DUF1668 PF07893.13 RJW60491.1 - 0.0016 17.9 0.0 0.061 12.7 0.0 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1668) Archease PF01951.16 RJW60492.1 - 2e-09 37.8 0.0 3.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) DNA_pol_phi PF04931.13 RJW60492.1 - 0.35 8.9 1.7 0.44 8.6 1.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Syndecan PF01034.20 RJW60493.1 - 1.8e-26 91.8 0.0 4e-26 90.7 0.0 1.6 2 0 0 2 2 2 1 Syndecan domain Thyroglobulin_1 PF00086.18 RJW60493.1 - 9.9e-05 21.9 1.2 0.00017 21.1 1.2 1.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Glycophorin_A PF01102.18 RJW60493.1 - 0.0005 20.3 0.2 0.0016 18.6 0.2 1.8 1 0 0 1 1 1 1 Glycophorin A HLH PF00010.26 RJW60494.1 - 4.5e-11 42.5 1.6 1.1e-10 41.3 1.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PI3K_C2 PF00792.24 RJW60495.1 - 0.0016 18.4 0.0 0.72 9.8 0.0 2.8 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 DUF2986 PF11661.8 RJW60495.1 - 6.2 7.4 7.7 0.58 10.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) PHO4 PF01384.20 RJW60496.1 - 3.8e-126 420.7 8.1 4.8e-126 420.4 8.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF390 PF04094.14 RJW60496.1 - 0.07 11.4 0.1 0.11 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) zf-C2H2 PF00096.26 RJW60498.1 - 4.2e-10 39.5 18.6 2.3e-05 24.6 1.8 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW60498.1 - 6.2e-05 23.2 7.1 0.0043 17.4 0.9 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW60498.1 - 7.3e-05 23.3 25.5 0.026 15.3 1.0 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 RJW60498.1 - 0.14 12.6 4.3 11 6.6 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW60498.1 - 0.26 11.6 4.4 6.6 7.1 1.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 RJW60498.1 - 1.5 8.8 7.6 15 5.7 0.3 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type YjeF_N PF03853.15 RJW60503.1 - 2.5e-38 131.7 0.0 2.9e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus Elongin_A PF06881.11 RJW60504.1 - 1.4e-19 70.5 0.1 3.4e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 RJW60504.1 - 3.2e-06 27.1 0.1 8.4e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CsgA PF17334.2 RJW60504.1 - 0.052 14.3 0.1 0.12 13.1 0.1 1.6 1 0 0 1 1 1 0 Minor curli fiber component A Pro_isomerase PF00160.21 RJW60505.1 - 1.2e-43 149.1 0.6 2.1e-43 148.3 0.6 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Swi3 PF07962.12 RJW60505.1 - 7.9e-24 83.5 0.0 1.6e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Pes-10 PF07149.11 RJW60505.1 - 0.34 9.9 4.9 0.59 9.1 4.9 1.3 1 0 0 1 1 1 0 Pes-10 PET PF06297.14 RJW60506.1 - 0.024 14.9 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 PET Domain ImpE PF07024.13 RJW60506.1 - 0.06 13.4 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 ImpE protein TetR_C_30 PF17939.1 RJW60508.1 - 0.025 14.8 0.0 0.1 12.9 0.0 2.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1216 PF06746.11 RJW60508.1 - 0.16 12.0 2.5 0.42 10.6 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) F_actin_bind PF08919.10 RJW60508.1 - 9 6.4 8.2 2.1 8.5 0.2 3.6 4 0 0 4 4 4 0 F-actin binding Usp PF00582.26 RJW60509.1 - 5.6e-27 95.0 0.0 6.9e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family MAP65_ASE1 PF03999.12 RJW60510.1 - 5.5e-42 144.3 9.6 7.9e-42 143.8 9.6 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Cas_Csn2 PF09711.10 RJW60510.1 - 0.0037 17.0 3.6 0.016 14.9 0.1 3.1 3 1 1 4 4 4 1 CRISPR-associated protein (Cas_Csn2) FANCI_S1-cap PF14674.6 RJW60510.1 - 2.4 8.3 5.7 49 4.1 0.0 3.8 4 0 0 4 4 4 0 FANCI solenoid 1 cap Pkinase_Tyr PF07714.17 RJW60511.1 - 3.9e-94 314.7 0.0 6e-94 314.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW60511.1 - 4e-44 151.0 0.0 6.1e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RJW60511.1 - 1.8e-20 72.8 0.1 4.4e-20 71.6 0.1 1.8 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 RJW60511.1 - 0.00011 21.7 0.0 0.00032 20.3 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RJW60511.1 - 0.0015 18.2 0.1 0.02 14.6 0.1 2.4 1 1 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 RJW60511.1 - 0.19 10.6 0.0 0.43 9.5 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Nucleo_P87 PF07267.11 RJW60511.1 - 3 6.6 4.7 5.1 5.8 4.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.12 RJW60511.1 - 3.7 5.6 9.0 5.6 5.0 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 RJW60511.1 - 3.7 7.2 6.1 12 5.5 6.1 1.8 1 0 0 1 1 1 0 FAM176 family TMEM101 PF15111.6 RJW60515.1 - 1.4e-07 31.4 7.3 2.4e-06 27.3 1.5 2.2 2 0 0 2 2 2 2 TMEM101 protein family eIF-1a PF01176.19 RJW60517.1 - 7.3e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Hjc PF01870.18 RJW60517.1 - 0.0011 19.0 0.1 0.0044 17.0 0.0 2.0 3 0 0 3 3 3 1 Archaeal holliday junction resolvase (hjc) Acyltransferase PF01553.21 RJW60519.1 - 2.5e-23 82.2 0.0 3.7e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TPR_12 PF13424.6 RJW60521.1 - 6.9e-64 212.1 27.8 1.1e-17 64.1 3.2 5.1 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 RJW60521.1 - 7.3e-56 184.7 11.9 2.1e-14 52.8 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 RJW60521.1 - 6.5e-30 100.9 15.4 2.2e-05 24.2 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 RJW60521.1 - 1.1e-25 88.3 27.0 2.6e-06 27.0 0.4 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 RJW60521.1 - 5.4e-19 66.7 25.6 0.00083 19.3 2.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 RJW60521.1 - 2.6e-13 49.0 21.6 0.024 14.8 0.2 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW60521.1 - 4.9e-10 39.3 7.1 6e-10 39.0 2.6 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 RJW60521.1 - 9.5e-10 39.0 12.5 0.004 17.8 1.7 5.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 RJW60521.1 - 1e-09 38.7 8.9 0.0065 17.0 0.2 4.6 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RJW60521.1 - 8.6e-09 35.5 7.8 1.2 10.1 0.3 6.6 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 RJW60521.1 - 1.2e-06 28.5 9.6 0.18 12.2 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 RJW60521.1 - 4.4e-06 26.8 0.1 4.5 8.2 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat SNAP PF14938.6 RJW60521.1 - 2.7e-05 23.8 1.5 3.1e-05 23.5 0.2 1.8 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP PPR PF01535.20 RJW60521.1 - 0.0011 19.0 0.4 2.9 8.3 0.0 4.5 6 0 0 6 6 5 1 PPR repeat ANAPC3 PF12895.7 RJW60521.1 - 0.0014 18.8 11.3 0.097 12.9 0.2 4.0 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.9 RJW60521.1 - 0.0049 16.6 2.3 0.32 10.7 0.1 2.9 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) RPN6_N PF18055.1 RJW60521.1 - 0.058 13.8 2.2 5.4 7.4 0.5 3.4 2 2 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain Clathrin PF00637.20 RJW60521.1 - 0.12 12.2 2.2 1.4 8.8 0.1 3.0 1 1 1 2 2 2 0 Region in Clathrin and VPS DUF627 PF04781.12 RJW60521.1 - 0.12 12.4 3.0 5.3 7.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_3 PF07720.12 RJW60521.1 - 0.55 10.3 10.1 2.6 8.1 0.2 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.18 RJW60521.1 - 2.2 8.4 12.7 1.8e+02 2.3 0.0 4.9 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 RJW60521.1 - 9.6 7.1 14.9 24 5.8 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ion_trans PF00520.31 RJW60522.1 - 4.8e-21 75.1 20.4 7.6e-21 74.4 20.4 1.3 1 0 0 1 1 1 1 Ion transport protein LSDAT_euk PF18139.1 RJW60522.1 - 1.2e-20 74.0 0.0 4.6e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 SLOG in TRPM LSDAT_prok PF18171.1 RJW60522.1 - 4.8e-07 29.2 0.0 1.2e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote PKD_channel PF08016.12 RJW60522.1 - 7.4e-05 21.6 18.3 0.00011 21.0 18.3 1.2 1 0 0 1 1 1 1 Polycystin cation channel Glyco_transf_21 PF13506.6 RJW60522.1 - 0.087 12.3 0.0 8 5.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 21 Phage_holin_3_6 PF07332.11 RJW60522.1 - 0.4 10.7 7.0 0.91 9.6 0.5 2.9 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RVT_1 PF00078.27 RJW60523.1 - 0.00034 20.2 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 RJW60525.1 - 5.9e-06 26.9 6.3 0.36 11.8 0.6 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 RJW60525.1 - 0.015 14.9 2.8 0.034 13.8 2.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 RJW60525.1 - 0.024 14.9 0.0 0.56 10.5 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PHD PF00628.29 RJW60525.1 - 4.2 7.4 5.5 3.7 7.5 2.9 2.2 2 0 0 2 2 2 0 PHD-finger CAP PF00188.26 RJW60526.1 - 9.8e-41 139.5 0.1 3.1e-21 76.5 0.0 2.7 3 0 0 3 3 3 2 Cysteine-rich secretory protein family 4_1_CTD PF05902.13 RJW60527.1 - 0.0055 16.8 0.3 0.84 9.7 0.0 2.6 1 1 1 2 2 2 2 4.1 protein C-terminal domain (CTD) ArAE_2 PF10334.9 RJW60527.1 - 0.025 14.4 0.6 6.5 6.5 0.1 2.2 1 1 1 2 2 2 0 Aromatic acid exporter family member 2 CH PF00307.31 RJW60528.1 - 2.1e-12 47.2 0.1 1.1e-06 28.8 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW60528.1 - 2.5e-05 24.0 0.1 0.0038 17.0 0.0 3.2 4 0 0 4 4 4 1 CAMSAP CH domain ASH PF15780.5 RJW60528.1 - 0.00052 20.2 0.0 0.13 12.4 0.0 2.7 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Sad1_UNC PF07738.13 RJW60529.1 - 3.8e-30 104.6 0.3 5.9e-29 100.7 0.1 2.3 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal PLAC8 PF04749.17 RJW60531.1 - 1.4e-14 54.8 20.3 2e-14 54.4 20.3 1.2 1 0 0 1 1 1 1 PLAC8 family zf-C2H2 PF00096.26 RJW60532.1 - 9.2e-21 73.1 29.5 3.3e-06 27.2 0.5 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW60532.1 - 3.7e-13 49.1 34.6 9.6e-05 22.9 0.4 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW60532.1 - 6.7e-12 45.3 27.6 7.6e-06 26.1 0.2 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW60532.1 - 1.6e-10 41.0 12.6 0.0096 16.2 0.1 4.5 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW60532.1 - 2.9e-07 30.6 19.6 0.0021 18.4 0.5 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RJW60532.1 - 0.00013 21.9 23.3 0.0055 16.7 0.3 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.12 RJW60532.1 - 0.0017 18.6 2.2 0.0017 18.6 2.2 3.1 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 RJW60532.1 - 0.0099 15.9 15.5 2.9 8.0 0.1 4.7 2 1 1 3 3 3 1 BED zinc finger zf-C2HE PF16278.5 RJW60532.1 - 0.022 15.2 20.1 1 9.9 3.4 4.7 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 RJW60532.1 - 0.27 11.4 11.4 0.37 10.9 2.1 2.8 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 RJW60532.1 - 0.32 11.8 9.1 0.75 10.6 1.3 2.5 2 0 0 2 2 2 0 zinc-ribbon family zf-C2H2_2 PF12756.7 RJW60532.1 - 1.4 9.3 18.0 0.58 10.5 0.8 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 RJW60532.1 - 1.9 8.5 15.4 14 5.7 0.1 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type HypA PF01155.19 RJW60532.1 - 3.8 7.6 8.7 1.4e+02 2.5 8.8 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Iso_dh PF00180.20 RJW60533.1 - 9.6e-68 228.9 0.0 1.1e-67 228.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IQ PF00612.27 RJW60534.1 - 7.2e-64 205.6 208.7 3.9e-06 26.2 0.7 25.4 24 1 1 25 25 25 22 IQ calmodulin-binding motif YidD PF01809.18 RJW60534.1 - 1.1 9.2 5.3 6.8 6.7 5.3 2.4 1 0 0 1 1 1 0 Putative membrane protein insertion efficiency factor DEAD PF00270.29 RJW60535.1 - 1.6e-40 138.8 0.1 2.7e-40 138.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW60535.1 - 1.5e-26 92.9 0.9 4.5e-24 84.9 0.2 2.8 2 1 1 3 3 3 2 Helicase conserved C-terminal domain CMS1 PF14617.6 RJW60535.1 - 4.8e-09 35.9 0.1 1.1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 RJW60535.1 - 1.1e-08 35.3 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 RJW60535.1 - 0.00043 19.9 0.0 0.00073 19.1 0.0 1.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 RJW60535.1 - 0.0094 16.3 0.1 0.025 14.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW60535.1 - 0.25 11.6 1.3 1.1 9.6 0.6 2.5 1 1 1 2 2 2 0 AAA domain RT_RNaseH PF17917.1 RJW60536.1 - 2.9e-07 30.7 0.0 5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Acyl_transf_3 PF01757.22 RJW60537.1 - 7.9e-16 58.0 18.5 7.9e-16 58.0 18.5 2.0 2 0 0 2 2 2 1 Acyltransferase family Ndc1_Nup PF09531.10 RJW60537.1 - 0.18 10.5 4.3 0.29 9.8 4.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UBA PF00627.31 RJW60540.1 - 3.6e-05 23.6 1.3 7.4e-05 22.6 1.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVT_1 PF00078.27 RJW60540.1 - 0.0089 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBA_4 PF14555.6 RJW60540.1 - 0.049 13.5 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 UBA-like domain Sugar_transport PF06800.12 RJW60541.1 - 0.13 11.6 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Sugar transport protein RUN PF02759.19 RJW60542.1 - 5.4e-15 55.5 0.0 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 RUN domain Asp PF00026.23 RJW60544.1 - 3.9e-22 79.1 0.0 4.8e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Guanylate_kin PF00625.21 RJW60547.1 - 2.5e-26 92.5 0.0 4.5e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ_6 PF17820.1 RJW60547.1 - 6.9e-09 35.4 0.0 3.4e-08 33.2 0.0 2.3 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 RJW60547.1 - 3.7e-06 26.5 0.0 7.3e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RJW60547.1 - 5.2e-06 26.0 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PDZ PF00595.24 RJW60547.1 - 4.8e-05 23.6 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 RJW60547.1 - 0.00012 21.9 0.1 0.00028 20.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 RJW60547.1 - 0.0031 17.8 0.0 0.016 15.5 0.0 2.2 2 1 0 2 2 2 1 PDZ domain L27 PF02828.16 RJW60547.1 - 0.0037 17.0 0.3 0.0089 15.8 0.3 1.6 1 0 0 1 1 1 1 L27 domain Cas1_AcylT PF07779.12 RJW60548.1 - 2.1e-117 392.9 40.1 1e-46 159.9 8.7 4.6 4 2 0 4 4 4 4 10 TM Acyl Transferase domain found in Cas1p Glycos_transf_2 PF00535.26 RJW60549.1 - 1.6e-30 106.2 0.0 4e-30 104.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RJW60549.1 - 2.3e-20 73.1 0.5 1e-19 71.1 0.5 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 RJW60549.1 - 0.00038 20.1 0.1 0.0008 19.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RJW60549.1 - 0.014 14.9 0.0 0.038 13.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 RJW60549.1 - 0.094 13.5 0.0 12 6.7 0.0 2.6 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like ATP_bind_3 PF01171.20 RJW60550.1 - 5.2e-17 62.2 0.0 1.3e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 RJW60550.1 - 9.1e-14 50.7 6.7 9.1e-14 50.7 6.7 3.8 5 0 0 5 5 5 1 Zinc-ribbon zf-HC5HC2H_2 PF13832.6 RJW60551.1 - 1.5e-25 89.5 3.8 1.5e-25 89.5 3.8 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RJW60551.1 - 2.4e-16 59.8 1.1 2.4e-16 59.8 1.1 3.3 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 RJW60551.1 - 1.2e-10 40.7 4.1 1.2e-10 40.7 4.1 3.0 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 RJW60551.1 - 1.2e-08 34.6 20.4 4.5e-07 29.7 7.8 2.9 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 RJW60551.1 - 0.0017 18.2 2.9 0.0017 18.2 2.9 4.0 3 1 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ycf34 PF10718.9 RJW60551.1 - 0.029 15.0 0.0 0.12 13.0 0.0 2.0 1 0 0 1 1 1 0 Hypothetical chloroplast protein Ycf34 Sas6_CC PF18594.1 RJW60551.1 - 0.099 12.4 1.7 0.18 11.6 1.7 1.4 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain PHD_4 PF16866.5 RJW60551.1 - 0.35 11.0 13.4 0.18 12.0 4.0 3.2 2 1 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 RJW60551.1 - 1.9 8.7 16.7 0.47 10.7 6.9 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger FliD_N PF02465.18 RJW60551.1 - 2.2 9.1 6.8 0.25 12.1 0.2 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Med6 PF04934.14 RJW60554.1 - 3.1e-40 137.0 0.0 4.2e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Thioredoxin PF00085.20 RJW60556.1 - 1.2e-12 47.7 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RJW60556.1 - 0.023 15.1 0.1 0.17 12.3 0.1 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain OST3_OST6 PF04756.13 RJW60556.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Homeodomain PF00046.29 RJW60557.1 - 9.1e-24 83.1 3.2 2.1e-23 81.9 3.2 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW60557.1 - 0.0098 15.8 0.2 0.066 13.1 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain MULE PF10551.9 RJW60558.1 - 6.6e-17 61.7 0.1 1.7e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain zf-C3H2C3 PF17122.5 RJW60558.1 - 0.0078 16.2 0.4 0.0078 16.2 0.4 2.5 3 0 0 3 3 3 1 Zinc-finger SWIM PF04434.17 RJW60558.1 - 0.028 14.1 0.2 0.06 13.0 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger UCH PF00443.29 RJW60559.1 - 2e-50 171.7 0.0 2.8e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW60559.1 - 1.7e-14 54.1 1.9 3.6e-10 39.9 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Dynein_light PF01221.18 RJW60560.1 - 4.6e-08 33.3 0.1 7.5e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Sec10 PF07393.11 RJW60562.1 - 4.6e-104 349.3 10.1 1.2e-71 242.2 0.0 3.0 1 1 2 3 3 3 3 Exocyst complex component Sec10 SlyX PF04102.12 RJW60562.1 - 0.17 12.5 0.7 1 10.1 0.7 2.4 1 0 0 1 1 1 0 SlyX Occludin_ELL PF07303.13 RJW60562.1 - 0.55 11.0 3.4 4.5 8.1 0.0 3.4 2 1 1 3 3 3 0 Occludin homology domain PTB PF08416.13 RJW60563.1 - 2.3e-06 27.8 0.0 4.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.28 RJW60563.1 - 1.5e-05 24.5 0.0 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RJW60563.1 - 0.00015 21.6 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RJW60563.1 - 0.0026 17.4 0.0 0.0087 15.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain ARTD15_N PF18084.1 RJW60565.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 ARTD15 N-terminal domain rve PF00665.26 RJW60568.1 - 7.3e-13 48.8 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RJW60568.1 - 0.032 14.0 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain GHL13 PF14883.6 RJW60568.1 - 0.095 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 TMEM223 PF14640.6 RJW60569.1 - 2.7e-15 56.9 0.2 1.8e-14 54.2 0.2 2.1 1 1 0 1 1 1 1 Transmembrane protein 223 Pkinase_Tyr PF07714.17 RJW60570.1 - 8e-87 290.8 0.0 1.3e-86 290.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW60570.1 - 4.3e-37 127.9 0.0 3.2e-35 121.8 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Ig_3 PF13927.6 RJW60570.1 - 3.2e-07 30.9 0.6 0.32 11.6 0.1 3.8 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RJW60570.1 - 9.1e-06 25.8 1.2 0.035 14.3 0.0 4.0 4 0 0 4 4 4 2 Immunoglobulin V-set domain Kinase-like PF14531.6 RJW60570.1 - 0.00029 20.3 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Adeno_E3_CR1 PF02440.15 RJW60570.1 - 0.0013 18.5 1.5 0.043 13.6 0.2 3.0 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 ig PF00047.25 RJW60570.1 - 0.0057 16.8 4.5 1.3 9.2 0.7 3.7 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 RJW60570.1 - 0.016 15.3 0.0 3.9 7.6 0.0 3.0 2 0 0 2 2 2 0 Immunoglobulin I-set domain Proteasome PF00227.26 RJW60571.1 - 2.7e-31 108.6 0.0 3.1e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-C2H2 PF00096.26 RJW60572.1 - 2e-15 56.2 28.1 0.00016 22.0 4.4 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW60572.1 - 4.3e-15 55.1 26.3 0.0021 18.8 0.7 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW60572.1 - 1.8e-12 47.1 22.6 0.00018 21.8 0.1 5.3 4 1 1 5 5 5 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW60572.1 - 1.5e-08 34.4 21.7 0.00024 21.0 0.2 4.1 4 1 0 4 4 3 3 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RJW60572.1 - 0.0004 20.0 18.1 0.007 16.0 2.5 3.7 2 1 2 4 4 4 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 RJW60572.1 - 0.0089 16.4 21.7 0.01 16.2 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW60572.1 - 0.025 14.9 15.9 0.44 10.9 0.0 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.14 RJW60572.1 - 0.26 11.2 11.5 4.3 7.4 0.2 3.5 3 1 1 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_3rep PF18868.1 RJW60572.1 - 0.3 11.8 9.5 3.5 8.3 1.8 3.3 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF1677 PF07911.13 RJW60572.1 - 0.66 10.4 7.2 6.6 7.2 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1677) zf-C2H2_2 PF12756.7 RJW60572.1 - 0.68 10.3 17.1 14 6.1 2.3 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 RJW60572.1 - 1.6 9.0 18.1 1 9.7 6.1 3.3 1 1 3 4 4 4 0 TFIIH C1-like domain zf-MYST PF17772.1 RJW60572.1 - 2 8.1 7.9 16 5.2 0.0 3.6 4 0 0 4 4 4 0 MYST family zinc finger domain zf-RING_5 PF14634.6 RJW60572.1 - 2.5 8.1 19.1 0.11 12.4 5.7 3.2 1 1 2 4 4 4 0 zinc-RING finger domain Ribosomal_S27e PF01667.17 RJW60572.1 - 2.8 7.7 9.5 10 5.9 0.3 3.4 3 1 1 4 4 4 0 Ribosomal protein S27 zf-LYAR PF08790.11 RJW60572.1 - 6.5 6.8 22.3 1.2 9.1 2.1 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger PHD PF00628.29 RJW60572.1 - 6.7 6.7 16.6 2.9 7.8 1.4 3.5 3 1 0 3 3 3 0 PHD-finger DUF2353 PF09789.9 RJW60573.1 - 3.4e-47 161.4 11.6 4.4e-47 161.0 11.6 1.0 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) SOGA PF11365.8 RJW60573.1 - 0.048 14.8 7.8 3 9.0 0.1 2.7 2 1 0 2 2 2 0 Protein SOGA CENP-F_leu_zip PF10473.9 RJW60573.1 - 0.46 10.5 14.0 0.3 11.1 8.4 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mac PF12464.8 RJW60573.1 - 1.1 9.5 4.2 5.3 7.4 4.2 2.3 1 1 0 1 1 1 0 Maltose acetyltransferase Pox_A_type_inc PF04508.12 RJW60573.1 - 1.6 8.7 7.9 0.29 11.1 2.7 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FAM184 PF15665.5 RJW60573.1 - 2.2 8.0 12.0 7.2 6.3 1.2 2.7 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B MATH PF00917.26 RJW60574.1 - 5.2e-07 29.8 0.0 1.4e-06 28.4 0.1 1.7 2 0 0 2 2 2 1 MATH domain DUF2599 PF10783.9 RJW60574.1 - 0.02 15.5 0.0 0.61 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2599) RRM_1 PF00076.22 RJW60575.1 - 9.5e-59 195.1 0.0 4e-19 68.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW60575.1 - 2.1e-10 40.3 0.0 6.4e-05 22.5 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RJW60575.1 - 0.00011 21.9 0.0 0.00043 20.1 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 RJW60575.1 - 0.13 12.5 0.0 18 5.5 0.0 3.4 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Pkinase_Tyr PF07714.17 RJW60576.1 - 4.1e-89 298.3 0.0 5.8e-89 297.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW60576.1 - 1.8e-44 152.1 0.0 2.7e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RJW60576.1 - 8.2e-28 96.3 2.4 5.5e-15 55.2 0.1 2.5 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.7 RJW60576.1 - 9.4e-16 58.2 1.1 3.9e-10 40.2 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RJW60576.1 - 2.4e-14 53.0 4.6 0.0025 18.2 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RJW60576.1 - 1.7e-12 47.6 1.4 1.8e-08 34.7 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW60576.1 - 6.8e-11 42.2 4.1 1.6e-06 28.3 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW60576.1 - 9.3e-11 41.0 6.4 0.011 16.1 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Haspin_kinase PF12330.8 RJW60576.1 - 0.00085 18.4 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RJW60576.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like MSC PF09402.10 RJW60578.1 - 5e-12 45.9 0.0 8.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Neurensin PF14927.6 RJW60578.1 - 0.058 13.1 0.6 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Neurensin CoA_binding_3 PF13727.6 RJW60578.1 - 0.093 12.7 2.3 0.073 13.1 0.4 1.7 2 0 0 2 2 2 0 CoA-binding domain Tom22 PF04281.13 RJW60578.1 - 0.22 11.3 0.1 0.47 10.2 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SP_C-Propep PF08999.10 RJW60578.1 - 0.55 10.0 2.6 20 5.0 0.2 2.4 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF5368 PF17336.2 RJW60578.1 - 5.2 7.3 7.4 15 5.8 4.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5368) WD40 PF00400.32 RJW60582.1 - 2e-34 117.0 25.5 2e-06 28.4 0.1 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 RJW60582.1 - 2.7e-10 40.0 3.4 2.7e-10 40.0 3.4 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RJW60582.1 - 0.00011 22.0 1.6 0.00044 20.0 0.4 2.6 2 0 0 2 2 2 1 F-box domain WD40_like PF17005.5 RJW60582.1 - 0.024 14.0 0.2 3.4 6.9 0.4 3.0 3 0 0 3 3 3 0 WD40-like domain ANAPC4_WD40 PF12894.7 RJW60582.1 - 0.079 13.3 1.8 4.3 7.7 0.1 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW60582.1 - 0.083 11.5 14.7 2.7 6.5 2.1 4.1 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Transferrin PF00405.17 RJW60583.1 - 1.3e-116 389.3 0.0 2.7e-76 256.9 0.0 2.1 2 0 0 2 2 2 2 Transferrin H-K_ATPase_N PF09040.11 RJW60584.1 - 0.36 11.3 2.4 28 5.2 0.0 3.7 3 1 1 4 4 4 0 Gastric H+/K+-ATPase, N terminal domain BTB PF00651.31 RJW60585.1 - 1e-25 90.1 0.9 2.5e-25 88.8 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 RJW60585.1 - 0.00044 20.3 0.4 0.0053 16.8 0.0 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Nop14 PF04147.12 RJW60585.1 - 0.082 11.1 13.1 0.19 9.9 13.1 1.5 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 RJW60585.1 - 9.6 6.2 23.8 2.4 8.2 12.6 2.4 2 0 0 2 2 2 0 YL1 nuclear protein MORN PF02493.20 RJW60586.1 - 0.00058 19.6 3.4 0.004 16.9 1.2 3.1 3 0 0 3 3 3 1 MORN repeat Sec8_exocyst PF04048.14 RJW60587.1 - 4.2e-07 29.9 0.5 1.3e-06 28.4 0.5 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain cNMP_binding PF00027.29 RJW60588.1 - 1.6e-24 85.8 0.1 1.4e-13 50.7 0.1 4.2 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain DUF4852 PF16144.5 RJW60588.1 - 0.067 13.3 0.3 0.067 13.3 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4852) DUF2689 PF10894.8 RJW60588.1 - 0.69 9.7 2.8 21 5.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2689) ABC_tran_Xtn PF12848.7 RJW60588.1 - 0.88 9.6 8.0 8.6 6.5 8.2 2.6 2 1 0 2 2 2 0 ABC transporter Ig_3 PF13927.6 RJW60590.1 - 1.4e-55 185.8 5.4 1e-13 51.7 0.1 6.4 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 RJW60590.1 - 1.1e-50 169.6 0.0 4.1e-12 46.0 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW60590.1 - 1.5e-28 99.0 5.4 1.5e-07 31.6 0.0 6.1 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 RJW60590.1 - 2.9e-26 91.5 10.0 1.9e-06 27.9 0.0 6.2 6 0 0 6 6 6 4 Immunoglobulin domain V-set PF07686.17 RJW60590.1 - 1e-21 77.1 0.6 1.8e-05 24.9 0.3 6.3 4 2 1 5 5 5 4 Immunoglobulin V-set domain fn3 PF00041.21 RJW60590.1 - 1.2e-10 41.5 8.6 0.012 16.0 0.0 5.7 6 0 0 6 6 6 3 Fibronectin type III domain Ig_6 PF18452.1 RJW60590.1 - 1.7e-10 40.3 0.1 0.073 12.6 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.12 RJW60590.1 - 1.3e-06 28.4 0.1 0.04 14.0 0.0 4.4 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 RJW60590.1 - 0.016 15.7 0.3 0.24 12.0 0.1 3.0 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 RJW60590.1 - 0.052 13.5 0.0 11 6.0 0.0 2.8 3 0 0 3 3 2 0 Fibronectin-III type domain fn3_2 PF16893.5 RJW60590.1 - 0.07 13.3 0.3 0.66 10.2 0.1 2.7 3 0 0 3 3 3 0 Fibronectin type III domain Ig_C17orf99 PF17736.1 RJW60590.1 - 0.43 10.6 4.3 25 5.0 0.0 4.3 5 0 0 5 5 5 0 C17orf99 Ig domain ADP_PFK_GK PF04587.15 RJW60590.1 - 1.3 7.5 3.4 0.52 8.8 1.0 1.5 2 0 0 2 2 2 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Tmemb_185A PF10269.9 RJW60591.1 - 4.1e-07 30.0 23.3 1.7e-06 28.0 22.9 2.2 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein LrgB PF04172.16 RJW60591.1 - 0.00069 19.2 1.7 0.00069 19.2 1.7 1.9 2 0 0 2 2 2 1 LrgB-like family RVT_1 PF00078.27 RJW60594.1 - 9e-05 22.1 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_2 PF08914.11 RJW60597.1 - 3.2e-20 72.1 2.5 1.5e-10 41.1 0.0 3.0 3 0 0 3 3 3 2 Rap1 Myb domain BRCT_2 PF16589.5 RJW60597.1 - 0.00011 22.5 0.0 0.0003 21.1 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-binding PF00249.31 RJW60597.1 - 0.0014 18.8 2.4 0.13 12.5 0.0 3.6 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RJW60597.1 - 0.0025 18.0 0.2 0.0076 16.5 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.8 RJW60597.1 - 0.071 13.2 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain GcrA PF07750.11 RJW60597.1 - 2.5 8.5 5.8 20 5.5 2.5 3.0 2 0 0 2 2 2 0 GcrA cell cycle regulator Mito_carr PF00153.27 RJW60598.1 - 1.7e-65 216.9 0.4 5.6e-22 77.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEK_C PF08766.11 RJW60599.1 - 3.1e-05 23.8 0.1 0.00011 22.1 0.1 1.9 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.27 RJW60599.1 - 0.00075 19.2 0.5 0.0015 18.2 0.5 1.5 1 0 0 1 1 1 1 SAP domain PGA2 PF07543.12 RJW60599.1 - 0.058 13.4 18.1 1 9.4 1.2 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 GAS PF13851.6 RJW60600.1 - 4.1e-50 169.9 23.6 4.1e-50 169.9 23.6 3.4 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding NapD PF03927.13 RJW60600.1 - 0.0066 16.5 0.3 0.036 14.1 0.2 2.4 2 0 0 2 2 2 1 NapD protein DUF1729 PF08354.10 RJW60600.1 - 0.011 14.7 13.3 0.11 11.4 4.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1729) Flagellin_C PF00700.21 RJW60600.1 - 0.021 15.1 1.3 0.021 15.1 1.3 4.0 4 0 0 4 4 4 0 Bacterial flagellin C-terminal helical region Baculo_PEP_C PF04513.12 RJW60600.1 - 0.084 12.9 23.1 1.1 9.4 5.7 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFIIA PF03153.13 RJW60602.1 - 0.87 9.5 12.8 1 9.3 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S4 PF00163.19 RJW60603.1 - 0.055 14.4 0.1 0.057 14.3 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain GAGA PF09237.11 RJW60607.1 - 0.0058 16.4 0.9 0.94 9.3 0.0 3.9 3 0 0 3 3 3 1 GAGA factor Mut7-C PF01927.16 RJW60607.1 - 0.0061 16.7 2.4 0.046 13.8 0.0 3.3 3 0 0 3 3 3 1 Mut7-C RNAse domain Acetone_carb_G PF08882.11 RJW60607.1 - 0.12 12.5 1.3 0.39 10.9 0.1 2.5 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit zf-C2H2_3rep PF18868.1 RJW60607.1 - 0.71 10.6 14.3 1.5 9.5 1.6 4.0 4 1 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 RJW60607.1 - 1 9.9 25.6 5 7.7 0.1 8.0 8 0 0 8 8 8 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW60607.1 - 1.4 9.0 0.0 1.4 9.0 0.0 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RJW60607.1 - 5.5 7.4 14.1 28 5.1 0.6 5.7 5 1 1 6 6 6 0 C2H2 type zinc-finger (2 copies) zf_CCCH_5 PF18384.1 RJW60608.1 - 2.2e-12 46.9 11.5 6e-12 45.5 11.5 1.8 1 0 0 1 1 1 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 RJW60608.1 - 0.0012 18.7 3.5 0.0012 18.7 3.5 6.1 5 1 0 5 5 5 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RJW60608.1 - 0.022 14.8 0.0 0.022 14.8 0.0 5.4 6 0 0 6 6 6 0 Zinc finger domain GOLGA2L5 PF15070.6 RJW60608.1 - 0.14 10.8 0.2 0.27 9.9 0.2 1.3 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Cep57_CLD_2 PF14197.6 RJW60608.1 - 0.17 12.0 2.6 0.36 10.9 2.6 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Lebercilin PF15619.6 RJW60608.1 - 0.21 11.2 1.4 0.4 10.3 1.4 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CLIP PF12032.8 RJW60608.1 - 1.1 9.6 8.0 17 5.8 0.2 4.5 4 1 0 4 4 4 0 Regulatory CLIP domain of proteinases DivIC PF04977.15 RJW60608.1 - 5.2 6.9 5.2 0.61 9.9 0.6 1.8 2 0 0 2 2 2 0 Septum formation initiator PIP49_C PF12260.8 RJW60609.1 - 2.3e-14 53.5 0.1 2.8e-08 33.6 0.0 2.7 2 1 0 2 2 2 2 Protein-kinase domain of FAM69 SLC3A2_N PF16028.5 RJW60609.1 - 6 6.5 5.6 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus zf-RING_2 PF13639.6 RJW60612.1 - 8.4e-14 51.6 4.0 8.4e-14 51.6 4.0 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 RJW60612.1 - 4.3e-11 42.4 0.8 4.3e-11 42.4 0.8 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RJW60612.1 - 3.1e-09 36.5 3.5 5.9e-09 35.6 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW60612.1 - 1.4e-08 34.6 1.9 2.9e-08 33.5 1.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RJW60612.1 - 5.6e-08 32.5 2.1 5.6e-08 32.5 2.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW60612.1 - 1e-07 32.1 3.4 2.8e-07 30.7 3.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RJW60612.1 - 2.3e-05 24.2 2.1 2.3e-05 24.2 2.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW60612.1 - 3.2e-05 23.9 0.5 3.2e-05 23.9 0.5 2.8 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RJW60612.1 - 0.00012 21.8 2.7 0.00027 20.8 2.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RJW60612.1 - 0.001 18.6 1.6 0.0028 17.3 1.6 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 RJW60612.1 - 0.02 14.9 2.7 0.05 13.6 2.7 1.7 1 1 0 1 1 1 0 Zinc-finger PHD PF00628.29 RJW60612.1 - 0.029 14.3 2.3 0.078 12.9 2.3 1.8 1 1 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 RJW60612.1 - 0.041 13.9 5.1 0.15 12.1 5.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 RJW60612.1 - 0.36 11.0 3.5 0.85 9.8 2.4 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 RJW60612.1 - 1.2 9.5 8.0 10 6.6 2.5 2.5 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.7 RJW60612.1 - 4.5 7.5 7.5 0.22 11.7 1.0 2.2 2 1 0 2 2 2 0 RING-variant domain MULE PF10551.9 RJW60613.1 - 5.9e-12 45.9 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain PX PF00787.24 RJW60615.1 - 3.8e-20 72.0 0.2 8.8e-20 70.8 0.2 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 RJW60615.1 - 0.018 14.6 1.0 0.63 9.5 0.4 2.2 2 0 0 2 2 2 0 Vps5 C terminal like DUF5456 PF17539.2 RJW60615.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5456) BIR PF00653.21 RJW60616.1 - 3.5e-11 43.6 0.1 5.4e-10 39.8 0.0 2.9 4 0 0 4 4 4 1 Inhibitor of Apoptosis domain zf-C3H2C3 PF17122.5 RJW60616.1 - 0.53 10.4 3.3 0.6 10.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger zf-ribbon_3 PF13248.6 RJW60616.1 - 5.4 6.6 5.7 1.4 8.4 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain SNARE PF05739.19 RJW60617.1 - 8.9e-17 60.8 3.4 1.2e-16 60.5 0.9 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 RJW60617.1 - 1.3e-05 25.0 10.6 7.6e-05 22.5 10.6 2.1 1 1 0 1 1 1 1 Syntaxin DUF5345 PF17280.2 RJW60617.1 - 0.025 14.6 0.2 0.025 14.6 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) TRP PF06011.12 RJW60617.1 - 0.1 11.3 0.6 0.099 11.4 0.6 1.3 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF3546 PF12066.8 RJW60618.1 - 4.9e-31 107.2 0.2 9.3e-31 106.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 RJW60618.1 - 3.5e-26 92.8 0.1 3.5e-26 92.8 0.1 2.4 2 0 0 2 2 2 1 Arsenite-resistance protein 2 Coilin_N PF15862.5 RJW60618.1 - 0.00074 19.3 0.1 0.16 11.8 0.0 3.4 1 1 0 2 2 2 1 Coilin N-terminus DUF629 PF04780.12 RJW60618.1 - 0.062 11.8 0.0 0.099 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) DUF1082 PF06449.11 RJW60619.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) RRM_1 PF00076.22 RJW60620.1 - 3.6e-37 126.0 0.2 2.8e-18 65.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW60620.1 - 3.2e-09 36.8 0.2 0.00053 20.1 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RJW60620.1 - 6.4e-05 22.9 0.1 0.16 12.0 0.1 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 RJW60620.1 - 0.00049 20.1 0.1 0.069 13.2 0.1 2.3 2 0 0 2 2 2 1 RNA binding motif PHM7_cyt PF14703.6 RJW60620.1 - 0.0021 18.3 0.4 0.034 14.4 0.2 2.7 1 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RL PF17797.1 RJW60620.1 - 0.021 14.8 0.0 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 RL domain XS PF03468.14 RJW60620.1 - 0.1 12.9 0.2 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 XS domain SF3a60_bindingd PF12108.8 RJW60620.1 - 0.15 12.0 0.5 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Ufd2P_core PF10408.9 RJW60621.1 - 9.1e-95 318.6 0.0 1.2e-50 172.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin elongating factor core U-box PF04564.15 RJW60621.1 - 8.1e-25 86.8 0.1 1.9e-24 85.6 0.1 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 RJW60621.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Mfa1 PF17445.2 RJW60623.1 - 4.7 7.3 8.1 0.39 10.8 1.1 2.9 3 0 0 3 3 3 0 Mating factor A1 FmiP_Thoc5 PF09766.9 RJW60624.1 - 8.8e-94 314.8 0.7 1.1e-93 314.4 0.7 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 RWD PF05773.22 RJW60624.1 - 0.025 14.9 0.0 0.077 13.3 0.0 2.0 1 0 0 1 1 1 0 RWD domain BLOC1_2 PF10046.9 RJW60624.1 - 2.4 8.5 5.2 28 5.1 0.6 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SH2 PF00017.24 RJW60627.1 - 3e-08 33.6 0.0 1.4e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 SH2 domain Phage_int_SAM_1 PF02899.17 RJW60628.1 - 0.11 12.9 0.4 0.15 12.4 0.4 1.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Histone_H2A_C PF16211.5 RJW60629.1 - 2.2e-19 68.9 1.6 3.5e-19 68.2 1.6 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 RJW60629.1 - 7.1e-15 55.5 0.0 8.9e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RJW60629.1 - 3.2e-06 27.3 0.0 4.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_C1 PF00112.23 RJW60631.1 - 2.7e-47 161.7 0.0 3.2e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease DUF3606 PF12244.8 RJW60631.1 - 0.011 15.6 0.1 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Glucosaminidase PF01832.20 RJW60631.1 - 0.077 13.5 0.3 0.3 11.6 0.3 1.8 2 1 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Peptidase_C1_2 PF03051.15 RJW60631.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family DSPc PF00782.20 RJW60632.1 - 9.4e-17 61.1 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 RJW60632.1 - 2.2e-07 30.6 0.0 2.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 RJW60632.1 - 1.8e-05 24.9 0.0 2.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 RJW60632.1 - 0.00011 21.8 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 RJW60632.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 RJW60632.1 - 0.06 13.3 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family EF-hand_7 PF13499.6 RJW60633.1 - 1.1e-23 83.5 3.5 4.3e-16 59.1 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW60633.1 - 7.2e-22 75.3 9.2 1.2e-06 27.6 0.5 4.0 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RJW60633.1 - 2.6e-20 70.5 0.5 2.3e-05 24.0 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RJW60633.1 - 2.3e-17 62.5 2.6 1.4e-07 31.2 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW60633.1 - 8.4e-17 59.8 4.2 1.6e-06 27.3 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 RJW60633.1 - 8.6e-06 25.6 0.8 0.19 11.7 0.0 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RJW60633.1 - 0.00055 20.2 0.3 0.47 10.8 0.0 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RJW60633.1 - 0.0021 18.3 0.0 0.0089 16.3 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 RJW60633.1 - 0.0023 17.8 0.6 2.3 8.2 0.0 3.1 3 1 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 RJW60633.1 - 0.019 15.2 0.3 1.6 9.0 0.2 2.8 1 1 1 2 2 2 0 Dockerin type I domain MecA_N PF05223.11 RJW60633.1 - 0.14 12.5 0.1 1.4 9.2 0.0 2.2 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain Runt PF00853.19 RJW60634.1 - 7e-11 41.8 0.2 1.2e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 Runt domain UQ_con PF00179.26 RJW60636.1 - 9.6e-27 93.3 0.0 1.4e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 RJW60639.1 - 1.7e-25 89.9 0.0 2.2e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60639.1 - 2.9e-16 59.6 0.0 3.6e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW60639.1 - 2.3e-09 36.6 0.2 3e-09 36.1 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RJW60639.1 - 0.052 13.5 1.6 6.4 6.6 0.3 2.6 2 1 0 3 3 3 0 Phosphotransferase enzyme family Aminotran_3 PF00202.21 RJW60641.1 - 0.0033 16.1 0.0 0.0037 16.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PARG_cat PF05028.14 RJW60642.1 - 5e-117 391.0 0.0 6.5e-117 390.6 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) CD36 PF01130.21 RJW60643.1 - 2.1e-28 99.1 0.0 2.6e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 CD36 family CD36 PF01130.21 RJW60644.1 - 2.3e-52 178.1 0.0 3.3e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 CD36 family TetR_C_15 PF17918.1 RJW60645.1 - 0.032 15.0 2.7 0.032 15.0 2.7 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RNA_pol_3_Rpc31 PF11705.8 RJW60645.1 - 1.6 8.9 15.1 2.1 8.6 15.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 zf-RING_2 PF13639.6 RJW60646.1 - 1.4e-06 28.5 9.8 4.3e-06 27.0 9.8 1.9 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 RJW60646.1 - 0.00094 19.3 4.8 0.003 17.7 4.8 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 RJW60646.1 - 0.0011 19.2 7.6 0.0031 17.8 7.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RJW60646.1 - 0.01 15.9 3.5 0.025 14.6 3.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 RJW60646.1 - 0.015 15.5 6.3 0.034 14.3 6.3 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 RJW60646.1 - 0.037 13.9 9.8 0.14 12.1 9.8 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 RJW60646.1 - 0.053 13.4 5.2 0.14 12.0 5.2 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 RJW60646.1 - 0.17 11.8 7.1 0.39 10.6 7.1 1.7 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 RJW60646.1 - 0.75 9.5 11.5 0.17 11.5 7.1 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 RJW60646.1 - 1.4 9.3 8.7 3.8 7.9 8.7 1.9 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 RJW60646.1 - 2.9 7.8 8.0 7.2 6.5 8.0 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-C3HC4_3 PF13920.6 RJW60646.1 - 6.8 6.6 8.7 19 5.2 8.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tetraspanin PF00335.20 RJW60647.1 - 0.023 14.4 0.2 0.043 13.5 0.2 1.5 2 0 0 2 2 2 0 Tetraspanin family stn_TNFRSF12A PF12191.8 RJW60647.1 - 0.054 13.7 1.2 0.11 12.7 1.2 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EphA2_TM PF14575.6 RJW60647.1 - 0.1 13.5 0.1 1.8 9.5 0.0 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Chordopox_A13L PF05961.11 RJW60647.1 - 0.12 12.6 1.8 0.14 12.4 0.4 1.8 2 0 0 2 2 2 0 Chordopoxvirus A13L protein TMEM132D_C PF15706.5 RJW60647.1 - 0.15 11.8 0.2 0.26 11.1 0.2 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Sarcoglycan_2 PF05510.13 RJW60647.1 - 0.3 9.8 0.0 0.44 9.3 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon TMIE PF16038.5 RJW60647.1 - 1.1 9.1 5.7 1.9 8.4 5.7 1.3 1 0 0 1 1 1 0 TMIE protein SBF2 PF12335.8 RJW60649.1 - 1e-10 41.7 0.6 1.5e-10 41.1 0.6 1.3 1 1 0 1 1 1 1 Myotubularin protein Folliculin PF11704.8 RJW60649.1 - 0.1 12.5 0.6 3.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Acetyltransf_10 PF13673.7 RJW60651.1 - 7.8e-06 25.8 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RJW60651.1 - 0.0013 19.1 0.0 0.0046 17.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Porphobil_deam PF01379.20 RJW60652.1 - 3.3e-73 245.6 0.1 4.4e-73 245.1 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 RJW60652.1 - 1.3e-10 41.5 0.0 5.1e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain HTH_AraC PF00165.23 RJW60653.1 - 0.0043 17.1 0.3 0.028 14.5 0.3 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family CD36 PF01130.21 RJW60655.1 - 6.8e-67 226.0 0.0 6.5e-49 166.7 0.0 2.0 1 1 1 2 2 2 2 CD36 family Y_phosphatase PF00102.27 RJW60657.1 - 4.4e-63 213.0 0.0 6.3e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RJW60657.1 - 0.0022 17.8 0.0 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RJW60657.1 - 0.0032 17.5 0.2 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Nop25 PF09805.9 RJW60657.1 - 2.8 8.4 8.8 4.9 7.6 1.3 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF1943 PF09172.11 RJW60658.1 - 2.6e-14 53.2 0.1 0.17 11.1 0.0 6.9 7 0 0 7 7 7 4 Domain of unknown function (DUF1943) DUF481 PF04338.12 RJW60658.1 - 0.0011 19.0 22.7 4.3 7.3 0.0 8.9 9 0 0 9 9 9 2 Protein of unknown function, DUF481 Bactofilin PF04519.13 RJW60658.1 - 0.0029 17.8 85.8 0.014 15.7 2.6 9.7 9 0 0 9 9 9 2 Polymer-forming cytoskeletal MspA PF09203.11 RJW60658.1 - 0.27 11.1 23.7 11 5.9 0.2 8.7 9 0 0 9 9 9 0 MspA NEAT PF05031.12 RJW60658.1 - 0.69 10.5 0.0 0.69 10.5 0.0 3.6 3 0 0 3 3 3 0 Iron Transport-associated domain Bcl-2 PF00452.19 RJW60659.1 - 3.1e-16 59.9 0.4 5.1e-16 59.2 0.4 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family DUF3198 PF11433.8 RJW60659.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) Ank_2 PF12796.7 RJW60660.1 - 1.6e-137 448.4 44.0 5.5e-20 71.7 0.1 11.8 2 2 10 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 RJW60660.1 - 7.2e-130 418.3 61.9 1.5e-07 31.5 0.0 22.6 21 1 1 22 22 22 21 Ankyrin repeat Ank_4 PF13637.6 RJW60660.1 - 3.1e-117 381.6 38.3 1.9e-13 50.6 0.1 16.2 5 4 12 18 18 18 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW60660.1 - 3.3e-109 343.5 35.8 2.3e-06 27.5 0.1 22.6 22 0 0 22 22 22 19 Ankyrin repeat Ank_5 PF13857.6 RJW60660.1 - 6e-108 351.5 46.3 1.8e-10 40.8 0.2 18.1 4 4 15 19 19 19 18 Ankyrin repeats (many copies) ZU5 PF00791.20 RJW60660.1 - 9.9e-29 99.6 1.3 1.7e-20 73.2 0.0 2.7 2 0 0 2 2 2 2 ZU5 domain UPA_2 PF17809.1 RJW60660.1 - 7.6e-28 97.0 0.0 2e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 UPA domain BTRD1 PF17660.1 RJW60660.1 - 0.18 11.6 0.0 18 5.2 0.0 3.7 4 0 0 4 4 4 0 Bacterial tandem repeat domain 1 Linocin_M18 PF04454.12 RJW60663.1 - 0.072 12.4 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Prenyltransf PF01255.19 RJW60665.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.5 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase QVR PF17064.5 RJW60666.1 - 0.0044 17.2 1.4 0.056 13.7 1.4 2.0 1 1 0 1 1 1 1 Sleepless protein RRM_1 PF00076.22 RJW60667.1 - 9.7e-28 95.8 0.0 2.6e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trnau1ap PF17654.1 RJW60667.1 - 0.61 11.0 5.6 0.51 11.2 3.8 1.8 2 0 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins K1 PF02960.14 RJW60668.1 - 0.029 14.5 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 K1 glycoprotein DUF1943 PF09172.11 RJW60669.1 - 0.005 16.1 0.0 0.3 10.3 0.0 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1943) Bactofilin PF04519.13 RJW60669.1 - 1.5 9.2 32.9 0.0098 16.2 2.3 6.7 7 0 0 7 7 7 0 Polymer-forming cytoskeletal Dpy-30 PF05186.13 RJW60670.1 - 4.6e-07 29.4 0.1 9.9e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 Dpy-30 motif zf-C2H2 PF00096.26 RJW60672.1 - 1.7e-21 75.4 55.5 7.3e-05 23.0 1.5 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW60672.1 - 5.2e-20 70.4 52.0 0.00012 22.7 1.3 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 RJW60672.1 - 5.1e-11 42.6 35.6 0.03 14.7 0.5 6.4 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW60672.1 - 1.5e-08 34.7 35.2 0.00038 20.7 0.4 6.2 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RJW60672.1 - 5.9e-07 29.6 54.4 0.00015 22.0 1.6 8.2 7 1 1 8 8 7 4 Zinc-finger double domain zf-C2H2_11 PF16622.5 RJW60672.1 - 6.4e-06 25.8 47.9 0.026 14.3 1.9 6.4 6 0 0 6 6 6 4 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 RJW60672.1 - 6.6e-06 25.9 23.3 0.04 13.8 0.2 5.7 5 0 0 5 5 5 3 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 RJW60672.1 - 1.3e-05 25.1 5.8 0.00014 21.8 0.5 6.7 7 0 0 7 7 6 4 C2H2-type zinc finger DUF2039 PF10217.9 RJW60672.1 - 0.045 14.1 13.6 1.9 8.9 0.7 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) DUF2256 PF10013.9 RJW60672.1 - 0.09 12.9 20.3 0.092 12.9 0.1 5.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 RJW60672.1 - 0.58 10.5 33.2 0.34 11.3 0.6 5.4 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.10 RJW60672.1 - 3.9 8.2 11.5 2.3 8.9 0.3 4.1 5 0 0 5 5 4 0 Protein of unknown function (FYDLN_acid) TF_Zn_Ribbon PF08271.12 RJW60672.1 - 6 6.5 8.0 31 4.2 0.0 4.3 5 0 0 5 5 5 0 TFIIB zinc-binding ARS2 PF04959.13 RJW60672.1 - 9.2 6.6 10.0 23 5.3 0.1 3.8 2 1 2 4 4 4 0 Arsenite-resistance protein 2 zf-FPG_IleRS PF06827.14 RJW60672.1 - 9.5 6.2 11.3 24 4.9 0.5 4.3 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Runt PF00853.19 RJW60673.1 - 5.2e-37 126.3 0.0 5.9e-37 126.1 0.0 1.0 1 0 0 1 1 1 1 Runt domain CD36 PF01130.21 RJW60674.1 - 4.7e-69 233.1 0.0 6.2e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 CD36 family DUF2357 PF09823.9 RJW60676.1 - 0.24 10.6 0.0 0.42 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) eIF2_C PF09173.11 RJW60678.1 - 1.9e-36 124.2 0.4 4e-36 123.1 0.4 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 RJW60678.1 - 1.7e-17 63.6 0.1 2.3e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RJW60678.1 - 5.1e-10 39.6 0.2 1.1e-09 38.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 RJW60678.1 - 0.0013 18.7 0.1 0.0028 17.6 0.1 1.5 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 RJW60678.1 - 0.02 14.9 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Pou PF00157.17 RJW60679.1 - 5.7e-29 99.9 0.1 1.4e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 RJW60679.1 - 1.4e-13 50.4 0.3 3.6e-13 49.1 0.3 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW60679.1 - 4.2e-05 23.4 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_31 PF13560.6 RJW60679.1 - 0.034 14.5 0.1 0.092 13.1 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain RVT_1 PF00078.27 RJW60680.1 - 1.7e-41 142.2 0.0 5.2e-41 140.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW60680.1 - 5.5e-08 32.7 0.1 1.4e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Pkinase PF00069.25 RJW60682.1 - 2.8e-30 105.6 0.0 4.1e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60682.1 - 1.2e-17 64.1 0.0 1.7e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF PF00617.19 RJW60683.1 - 1.9e-42 145.5 0.4 4.2e-42 144.3 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain Dynein_C PF18199.1 RJW60685.1 - 5.7e-70 236.0 0.0 7.8e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RJW60685.1 - 4e-23 82.0 0.1 1.3e-22 80.4 0.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain RRM_1 PF00076.22 RJW60686.1 - 3.1e-08 33.3 0.0 9.6e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DSPc PF00782.20 RJW60689.1 - 3.7e-20 72.1 0.0 5.3e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Yippee-Mis18 PF03226.14 RJW60689.1 - 0.055 13.7 0.3 0.13 12.5 0.3 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Y_phosphatase PF00102.27 RJW60689.1 - 0.058 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase BEN PF10523.9 RJW60690.1 - 0.0017 18.6 0.0 0.0037 17.5 0.0 1.6 1 0 0 1 1 1 1 BEN domain RVT_1 PF00078.27 RJW60691.1 - 2.7e-45 154.6 0.0 4.8e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW60691.1 - 0.00011 21.8 0.5 0.00024 20.7 0.5 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_6 PF12774.7 RJW60693.1 - 2.3e-121 404.8 0.0 5.3e-121 403.6 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 RJW60693.1 - 8.7e-114 381.2 4.0 3.8e-113 379.1 3.8 2.2 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RJW60693.1 - 1.4e-111 373.5 1.5 1.4e-111 373.5 1.5 3.7 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA PF00004.29 RJW60693.1 - 0.02 15.3 0.2 0.31 11.5 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ApoLp-III PF07464.11 RJW60693.1 - 0.22 11.6 4.7 14 5.7 0.1 4.2 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF5320 PF17253.2 RJW60693.1 - 0.3 12.2 1.1 2 9.5 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Glyco_hydro_19 PF00182.19 RJW60696.1 - 1.1e-30 107.2 0.5 1.2e-28 100.6 0.5 2.2 1 1 0 1 1 1 1 Chitinase class I AIG2_2 PF13772.6 RJW60699.1 - 0.00011 22.5 0.0 0.00023 21.5 0.0 1.5 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 RJW60699.1 - 0.00013 22.6 0.0 0.00021 21.9 0.0 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF418 PF04235.12 RJW60699.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF418) Peptidase_M13_N PF05649.13 RJW60700.1 - 1.1e-86 291.9 1.4 1.1e-86 291.9 1.4 1.4 2 0 0 2 2 2 1 Peptidase family M13 Aldo_ket_red PF00248.21 RJW60702.1 - 9.6e-44 149.7 0.0 4.5e-43 147.5 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family YqzE PF14038.6 RJW60703.1 - 0.68 10.0 0.0 0.68 10.0 0.0 3.6 3 0 0 3 3 3 0 YqzE-like protein CGI-121 PF08617.10 RJW60705.1 - 2.3e-27 96.1 0.0 2.6e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 GMP_PDE_delta PF05351.11 RJW60706.1 - 1.4e-48 164.9 3.2 2.8e-42 144.4 2.8 2.1 2 0 0 2 2 2 2 GMP-PDE, delta subunit zf-ZPR1 PF03367.13 RJW60709.1 - 2.6e-93 310.1 0.0 1.9e-45 154.5 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 RJW60709.1 - 0.00021 21.3 0.4 0.063 13.3 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRPl_C4 PF17026.5 RJW60709.1 - 0.0081 16.2 0.5 9.2 6.4 0.0 3.3 3 0 0 3 3 3 1 Putative ribonucleoprotein zinc-finger pf C4 type CpXC PF14353.6 RJW60709.1 - 0.015 15.4 1.0 13 5.8 0.0 3.2 3 1 0 3 3 3 0 CpXC protein zf-ribbon_3 PF13248.6 RJW60709.1 - 0.24 10.9 8.7 13 5.4 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 RJW60709.1 - 0.31 11.1 1.7 0.74 9.8 0.1 2.3 2 1 0 2 2 2 0 zinc-ribbons UPF0547 PF10571.9 RJW60709.1 - 0.5 10.5 5.3 4.6 7.4 0.2 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DZR PF12773.7 RJW60709.1 - 4 7.5 9.5 2.1 8.4 1.2 3.4 2 2 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 RJW60709.1 - 4.6 7.4 7.6 4.7 7.4 2.2 3.5 3 1 0 3 3 3 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 RJW60709.1 - 6.3 6.4 6.3 47 3.6 0.2 3.6 3 0 0 3 3 3 0 TFIIB zinc-binding LIM PF00412.22 RJW60710.1 - 9.3e-10 38.6 8.6 1e-09 38.4 8.6 1.1 1 0 0 1 1 1 1 LIM domain Zn_ribbon_2 PF12674.7 RJW60710.1 - 0.067 13.9 5.3 0.084 13.5 5.3 1.1 1 0 0 1 1 1 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.10 RJW60710.1 - 0.34 11.1 7.1 0.44 10.7 7.1 1.2 1 0 0 1 1 1 0 Zinc ribbon domain FH2 PF02181.23 RJW60711.1 - 4.8e-87 292.5 2.4 4.8e-87 292.5 2.4 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 RJW60711.1 - 9.4e-36 123.3 0.0 9.4e-36 123.3 0.0 2.7 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 RJW60711.1 - 1.3e-24 86.8 0.5 3.4e-24 85.4 0.5 1.7 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_DAD PF06345.11 RJW60711.1 - 0.0071 16.3 1.4 0.013 15.5 0.1 2.2 2 0 0 2 2 2 1 DRF Autoregulatory Domain DUF3502 PF12010.8 RJW60711.1 - 0.65 10.6 2.4 2.4 8.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3502) Drf_FH1 PF06346.12 RJW60711.1 - 7.9 6.2 80.8 0.011 15.5 68.1 2.4 3 0 0 3 3 3 0 Formin Homology Region 1 RAG1_imp_bd PF12560.8 RJW60711.1 - 8.3 5.9 6.3 0.36 10.3 0.6 1.6 2 0 0 2 2 2 0 RAG1 importin binding Aldo_ket_red PF00248.21 RJW60712.1 - 2.8e-48 164.6 0.0 1.9e-47 161.9 0.0 2.2 1 1 1 2 2 2 1 Aldo/keto reductase family ASH PF15780.5 RJW60714.1 - 4.2e-27 94.2 22.0 2.6e-05 24.3 0.0 17.3 18 1 1 19 19 19 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Hydin_ADK PF17213.3 RJW60714.1 - 4.2e-22 79.4 4.4 4.2e-22 79.4 4.4 3.6 2 1 0 2 2 2 1 Hydin Adenylate kinase-like domain PapD-like PF14874.6 RJW60714.1 - 1.4e-20 73.4 11.1 0.49 10.6 0.0 10.9 10 0 0 10 10 10 6 Flagellar-associated PapD-like Motile_Sperm PF00635.26 RJW60714.1 - 2e-11 43.7 4.8 3.3 7.6 0.0 10.6 13 0 0 13 13 13 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 RJW60714.1 - 9e-07 28.8 1.8 19 5.4 0.0 9.4 11 1 0 11 11 11 1 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 RJW60714.1 - 1.7e-06 28.2 3.1 0.97 9.7 0.0 7.8 7 0 0 7 7 7 2 Transmembrane protein 131-like DUF5001 PF16392.5 RJW60714.1 - 0.03 14.2 3.4 9.5 6.2 0.0 6.5 9 1 1 10 10 10 0 Ig-like domain Pkinase PF00069.25 RJW60715.1 - 3.8e-76 255.9 0.0 5.1e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60715.1 - 7.6e-33 113.9 0.0 1.7e-32 112.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW60715.1 - 0.0023 17.3 0.0 0.28 10.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 RJW60715.1 - 0.0032 16.5 1.7 0.0052 15.8 0.0 1.8 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 RJW60715.1 - 0.0096 15.5 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 1 RIO1 family MMS1_N PF10433.9 RJW60717.1 - 2.3e-67 227.7 0.0 5.9e-67 226.4 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 RJW60717.1 - 1.2e-60 205.6 0.0 7e-60 203.0 0.0 2.3 2 1 0 2 2 2 1 CPSF A subunit region zf-nanos PF05741.13 RJW60718.1 - 1.4e-45 153.3 12.7 1.7e-22 79.4 2.3 2.6 2 0 0 2 2 2 2 Nanos RNA binding domain Sulfotransfer_3 PF13469.6 RJW60718.1 - 0.068 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Sulfotransferase family FAA_hydro_N_2 PF18288.1 RJW60718.1 - 0.19 12.1 0.2 13 6.3 0.0 2.4 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DUF3716 PF12511.8 RJW60718.1 - 1.5 8.9 5.2 14 5.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Opy2 PF09463.10 RJW60718.1 - 3.7 8.0 9.2 19 5.7 1.3 3.1 2 0 0 2 2 2 0 Opy2 protein Na_Ca_ex PF01699.24 RJW60719.1 - 3.2e-39 134.3 37.5 1.2e-20 74.0 21.0 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Guanylate_cyc_2 PF09778.9 RJW60720.1 - 0.032 13.6 0.1 0.09 12.1 0.1 1.7 1 0 0 1 1 1 0 Guanylylate cyclase Abhydrolase_6 PF12697.7 RJW60721.1 - 1.4e-22 81.4 0.5 1.4e-22 81.4 0.5 3.5 3 2 0 3 3 3 1 Alpha/beta hydrolase family CIA30 PF08547.12 RJW60721.1 - 2.3e-21 76.4 0.0 1.4e-18 67.4 0.0 2.6 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Abhydrolase_1 PF00561.20 RJW60721.1 - 1.5e-11 44.4 1.3 1.2e-10 41.5 1.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RJW60721.1 - 3.2e-10 39.7 0.0 1.4e-09 37.6 0.1 2.0 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 RJW60721.1 - 3.7e-06 27.2 0.0 7.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 RJW60721.1 - 6.4e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 RJW60721.1 - 0.016 14.9 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 RJW60721.1 - 0.029 14.2 1.2 0.15 11.9 1.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 RJW60721.1 - 0.031 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) RVT_1 PF00078.27 RJW60721.1 - 0.035 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Chlorophyllase2 PF12740.7 RJW60721.1 - 0.037 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 RJW60721.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 RJW60721.1 - 0.14 12.1 0.2 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) RRM_1 PF00076.22 RJW60723.1 - 2.1e-09 37.1 0.0 0.0005 19.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.24 RJW60724.1 - 6.2e-146 486.9 2.0 7.7e-146 486.6 2.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-ribbon_3 PF13248.6 RJW60725.1 - 0.083 12.3 0.7 2.6 7.6 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Cys_rich_CPXG PF14255.6 RJW60725.1 - 0.18 11.7 1.0 22 5.0 0.0 3.0 2 0 0 2 2 2 0 Cysteine-rich CPXCG Nup54 PF13874.6 RJW60726.1 - 5.9e-33 113.9 0.0 5.9e-33 113.9 0.0 2.5 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 RVT_1 PF00078.27 RJW60727.1 - 1.9e-44 151.9 0.0 2.9e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_1 PF00515.28 RJW60727.1 - 3.3e-31 105.8 1.2 0.00018 21.2 0.0 9.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 RJW60727.1 - 1.2e-30 103.2 5.2 0.00068 19.6 0.1 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 RJW60727.1 - 2.7e-22 78.2 0.0 0.00036 20.2 0.0 6.9 5 3 2 7 7 7 7 TPR repeat TPR_8 PF13181.6 RJW60727.1 - 1.6e-21 74.6 1.6 0.0016 18.5 0.0 9.1 10 0 0 10 10 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW60727.1 - 9.8e-21 73.8 14.1 3.1e-16 59.3 1.2 6.0 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RJW60727.1 - 5.5e-19 67.2 6.4 0.035 14.9 0.0 10.2 6 3 5 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 RJW60727.1 - 5.1e-17 61.9 12.3 0.00013 22.2 0.0 7.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 RJW60727.1 - 1.2e-14 53.5 3.3 0.14 12.6 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 RJW60727.1 - 2.5e-13 50.4 13.7 2.4e-06 28.1 0.4 8.1 6 2 1 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW60727.1 - 4.5e-13 49.5 7.1 0.011 16.2 0.0 7.6 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 RJW60727.1 - 8.8e-10 38.6 2.1 1.3 9.8 0.0 8.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW60727.1 - 1e-07 31.4 7.7 0.031 14.3 0.0 7.4 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW60727.1 - 5.2e-07 29.7 8.9 0.033 14.3 0.1 4.7 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 RJW60727.1 - 0.003 17.4 3.6 17 5.5 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 RJW60730.1 - 4.1e-09 36.9 4.0 0.051 14.5 0.1 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW60730.1 - 0.024 14.9 0.0 50 4.3 0.0 3.9 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3402 PF11882.8 RJW60731.1 - 1.3e-93 314.6 25.2 1.2e-58 199.4 7.5 3.8 2 1 2 4 4 4 3 Domain of unknown function (DUF3402) RVT_1 PF00078.27 RJW60731.1 - 2.7e-46 157.9 0.5 1.5e-45 155.4 0.0 2.4 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) N1221 PF07923.13 RJW60731.1 - 8.1e-40 136.8 0.0 1.5e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein Exo_endo_phos_2 PF14529.6 RJW60731.1 - 1e-11 44.7 0.1 1.1e-10 41.4 0.0 2.9 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Replicase PF03090.17 RJW60731.1 - 0.14 12.0 0.1 0.42 10.4 0.1 1.7 1 0 0 1 1 1 0 Replicase family zf-nanos PF05741.13 RJW60732.1 - 8e-23 80.4 4.1 9.7e-23 80.2 2.9 1.8 2 0 0 2 2 2 1 Nanos RNA binding domain ASH PF15780.5 RJW60733.1 - 1.7e-07 31.4 2.4 0.12 12.5 0.0 4.7 5 0 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin zf-Di19 PF05605.12 RJW60734.1 - 7.2e-05 23.0 0.5 7.2e-05 23.0 0.5 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 RJW60734.1 - 0.0001 21.9 0.2 0.0001 21.9 0.2 3.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 RJW60734.1 - 0.00011 21.8 6.1 1.1 9.0 0.9 4.2 3 1 1 4 4 4 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 RJW60734.1 - 0.00016 21.9 12.3 0.24 12.0 0.2 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 RJW60734.1 - 0.0014 19.3 0.2 0.22 12.2 0.0 2.6 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 RJW60734.1 - 0.0096 16.7 13.4 6.1 8.0 0.6 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger DUF2894 PF11445.8 RJW60734.1 - 0.075 13.5 0.9 0.27 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) OrsD PF12013.8 RJW60734.1 - 0.15 12.5 7.0 1.7 9.1 0.1 3.5 2 2 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_2 PF13465.6 RJW60734.1 - 2.5 8.7 13.9 0.41 11.2 0.2 4.0 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW60734.1 - 9.3 6.7 6.3 1.1 9.6 0.6 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 RJW60735.1 - 2.1e-25 89.6 0.0 2.8e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW60735.1 - 8.3e-14 51.5 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW60735.1 - 3.2e-09 36.0 0.2 3.2e-09 36.0 0.2 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RJW60735.1 - 0.00012 22.2 0.4 0.0065 16.4 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RJW60735.1 - 0.039 13.3 0.1 0.072 12.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aminotran_4 PF01063.19 RJW60736.1 - 8.6e-23 81.4 0.0 1e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV ASH PF15780.5 RJW60737.1 - 3.6e-13 49.5 11.7 0.0096 16.1 0.0 9.6 10 2 1 11 11 11 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MYCBPAP PF14646.6 RJW60737.1 - 1.9e-08 33.7 0.4 0.022 13.7 0.1 4.6 5 0 0 5 5 5 3 MYCBP-associated protein family Motile_Sperm PF00635.26 RJW60737.1 - 4.8e-06 26.4 0.6 3.9 7.4 0.0 5.2 5 0 0 5 5 5 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 RJW60737.1 - 9.7e-06 25.5 1.9 11 6.2 0.0 7.3 8 1 0 8 8 8 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 RJW60737.1 - 1.9e-05 24.8 2.4 0.86 9.9 0.0 6.1 6 0 0 6 6 6 2 Transmembrane protein 131-like AAA_7 PF12775.7 RJW60738.1 - 2.1e-76 255.5 0.1 2.4e-76 255.3 0.1 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 RJW60738.1 - 9.4e-08 32.2 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 RJW60738.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 RJW60738.1 - 0.0044 17.3 0.0 0.033 14.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 RJW60738.1 - 0.0063 16.9 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 RJW60738.1 - 0.014 15.7 0.1 0.14 12.6 0.1 2.6 1 1 2 3 3 3 0 RNA helicase Mg_chelatase PF01078.21 RJW60738.1 - 0.035 13.5 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 RJW60738.1 - 0.069 13.7 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 RJW60738.1 - 0.085 13.3 0.6 0.19 12.1 0.1 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GFRP PF06399.13 RJW60738.1 - 0.15 12.0 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) AAA_33 PF13671.6 RJW60738.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF5380 PF17351.2 RJW60741.1 - 0.054 13.3 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5380) zf-C4 PF00105.18 RJW60747.1 - 3e-27 94.9 14.5 6e-27 93.9 14.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW60747.1 - 4.9e-13 49.1 0.0 8.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Galactosyl_T PF01762.21 RJW60748.1 - 1.5e-25 90.2 0.0 3.2e-24 85.8 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Sec62 PF03839.16 RJW60749.1 - 5.5e-64 215.6 0.1 1.1e-63 214.7 0.1 1.4 1 0 0 1 1 1 1 Translocation protein Sec62 RVT_1 PF00078.27 RJW60749.1 - 1e-19 70.9 0.0 6.2e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW60749.1 - 0.00027 20.5 0.6 0.00055 19.5 0.6 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mem_trans PF03547.18 RJW60750.1 - 5.5e-14 51.3 3.1 5.5e-14 51.3 3.1 3.2 3 0 0 3 3 3 2 Membrane transport protein LRR19-TM PF15176.6 RJW60750.1 - 0.15 12.1 0.1 0.54 10.3 0.1 2.0 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Pex24p PF06398.11 RJW60750.1 - 0.18 10.8 1.3 0.41 9.6 0.0 2.3 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin SMC_N PF02463.19 RJW60752.1 - 6.7e-15 55.1 3.5 8e-15 54.9 3.5 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain FtsK_alpha PF17854.1 RJW60752.1 - 0.012 15.8 0.8 5 7.3 0.0 3.2 2 1 0 3 3 3 0 FtsK alpha domain GAS PF13851.6 RJW60752.1 - 0.075 12.4 28.6 0.46 9.8 5.7 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 RJW60752.1 - 0.46 8.4 9.4 0.61 7.9 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 RJW60752.1 - 2.2 6.7 5.6 3.9 5.9 5.6 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_23 PF13476.6 RJW60752.1 - 2.7 8.4 21.0 2 8.9 2.0 2.5 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.11 RJW60752.1 - 3.3 6.5 29.4 0.95 8.3 15.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 RJW60752.1 - 3.5 7.8 13.5 0.19 11.8 3.7 3.7 3 2 0 3 3 3 0 TolA binding protein trimerisation Phlebovirus_NSM PF07246.11 RJW60752.1 - 7.9 5.8 15.0 2.4 7.4 11.0 2.0 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M C2 PF00168.30 RJW60755.1 - 9.3e-05 22.7 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain Ig_3 PF13927.6 RJW60757.1 - 1.2e-45 154.0 3.4 4.5e-11 43.2 0.1 10.7 10 2 0 10 10 10 7 Immunoglobulin domain fn3 PF00041.21 RJW60757.1 - 6.9e-45 151.3 13.6 1.4e-12 47.8 0.5 8.1 7 2 0 7 7 7 6 Fibronectin type III domain I-set PF07679.16 RJW60757.1 - 6.1e-36 122.4 1.3 5e-08 32.9 0.0 11.4 10 2 1 11 11 11 6 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW60757.1 - 8.3e-26 90.1 0.3 0.00026 21.3 0.0 9.2 9 0 0 9 9 9 5 Immunoglobulin domain ig PF00047.25 RJW60757.1 - 1.2e-17 63.9 7.0 0.00025 21.1 0.0 9.6 11 1 0 11 11 11 3 Immunoglobulin domain V-set PF07686.17 RJW60757.1 - 1.7e-16 60.3 0.5 0.00054 20.1 0.0 8.2 7 1 0 7 7 7 3 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 RJW60757.1 - 4.5e-08 33.5 3.2 0.19 12.3 0.2 5.7 5 1 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 RJW60757.1 - 1.4e-05 24.5 0.0 0.24 11.0 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 RJW60757.1 - 0.00062 19.8 1.4 2.2 8.4 0.0 4.6 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 RJW60757.1 - 0.0065 16.7 0.0 12 6.2 0.0 4.0 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Fimbrial_PilY2 PF14481.6 RJW60760.1 - 0.008 15.8 0.0 0.016 14.8 0.0 1.5 2 0 0 2 2 2 1 Type 4 fimbrial biogenesis protein PilY2 bVLRF1 PF18826.1 RJW60764.1 - 1.7e-31 109.1 5.3 2.7e-27 95.5 0.0 2.7 3 0 0 3 3 3 2 bacteroidetes VLRF1 release factor VATC PF18716.1 RJW60764.1 - 1e-09 38.0 4.5 1e-09 38.0 4.5 2.0 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_2 PF12796.7 RJW60764.1 - 0.00024 21.6 0.0 0.00067 20.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW60764.1 - 0.0019 18.5 0.0 0.0048 17.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW60764.1 - 0.0024 18.2 0.0 0.019 15.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RJW60764.1 - 0.0026 18.1 0.0 0.011 16.2 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeat DUF3449 PF11931.8 RJW60764.1 - 0.039 13.8 1.9 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Insulin PF00049.18 RJW60764.1 - 2.9 8.9 5.1 6.2 7.9 0.0 3.0 2 0 0 2 2 2 0 Insulin/IGF/Relaxin family VASt PF16016.5 RJW60765.1 - 0.06 13.8 0.1 0.15 12.4 0.1 1.6 1 1 1 2 2 2 0 VAD1 Analog of StAR-related lipid transfer domain DUF5535 PF17687.1 RJW60766.1 - 0.027 14.6 0.0 0.092 12.9 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5535) Peptidase_S24 PF00717.23 RJW60767.1 - 2.2e-09 37.1 0.1 3.6e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF4590 PF15257.6 RJW60770.1 - 6.3e-33 113.1 0.3 1.5e-32 111.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) HCO3_cotransp PF00955.21 RJW60774.1 - 4.7e-78 263.2 16.5 1.2e-76 258.6 16.5 2.1 1 1 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 RJW60774.1 - 3e-28 99.4 2.2 7e-28 98.2 0.0 2.3 2 0 0 2 2 2 1 Band 3 cytoplasmic domain EnY2 PF10163.9 RJW60775.1 - 1.5e-24 86.2 0.2 1.7e-24 86.0 0.2 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Spore_III_AB PF09548.10 RJW60777.1 - 0.017 15.2 1.0 0.025 14.7 1.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Astro_capsid_p PF12226.8 RJW60777.1 - 0.039 13.1 1.6 0.056 12.6 1.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EF-hand_7 PF13499.6 RJW60777.1 - 0.46 11.0 5.4 0.37 11.3 1.2 2.2 1 1 1 2 2 2 0 EF-hand domain pair TB2_DP1_HVA22 PF03134.19 RJW60778.1 - 4.6e-23 80.9 1.4 1.4e-22 79.4 1.4 1.9 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RVT_1 PF00078.27 RJW60778.1 - 2.2e-12 46.9 0.0 1.5e-11 44.2 0.0 2.3 3 1 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Neur_chan_LBD PF02931.23 RJW60782.1 - 5.7e-63 212.2 3.6 6.9e-63 212.0 3.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW60782.1 - 9e-07 29.2 0.4 1.4e-06 28.6 0.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region zf-met PF12874.7 RJW60784.1 - 2.3e-06 27.8 1.9 6.9e-06 26.3 1.9 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW60784.1 - 0.046 14.0 3.6 0.09 13.1 1.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Neur_chan_LBD PF02931.23 RJW60785.1 - 1e-59 201.6 3.9 5e-59 199.4 2.0 2.2 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW60785.1 - 3.8e-35 122.1 5.3 1.5e-34 120.1 5.3 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ran-binding PF05508.11 RJW60786.1 - 0.17 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 RanGTP-binding protein EF-hand_7 PF13499.6 RJW60787.1 - 1.1e-15 57.9 0.3 3.9e-08 33.6 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW60787.1 - 2.8e-15 54.6 0.2 2.7e-06 26.5 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RJW60787.1 - 1.2e-14 52.9 0.8 8.2e-06 25.4 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 RJW60787.1 - 2.7e-11 42.4 0.3 2e-05 23.8 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW60787.1 - 1.1e-09 38.0 0.1 1.7e-05 24.6 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW60787.1 - 0.00044 20.5 0.0 0.48 10.8 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW60787.1 - 0.068 13.1 0.1 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Hyd_WA PF06462.12 RJW60788.1 - 0.19 11.8 0.0 27 4.9 0.0 2.6 2 0 0 2 2 2 0 Propeller Nitro_FeMo-Co PF02579.17 RJW60789.1 - 0.075 13.4 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Fz PF01392.22 RJW60790.1 - 5.9e-31 107.4 2.3 9.5e-31 106.7 2.3 1.3 1 0 0 1 1 1 1 Fz domain Frizzled PF01534.17 RJW60790.1 - 4.2e-26 91.8 3.0 6.5e-26 91.1 3.0 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Arfaptin PF06456.13 RJW60792.1 - 6.1e-75 251.7 9.7 8e-75 251.3 9.7 1.1 1 0 0 1 1 1 1 Arfaptin-like domain ICA69 PF04629.14 RJW60792.1 - 3.1e-13 50.6 9.4 1.7e-12 48.2 9.4 2.2 1 1 0 1 1 1 1 Islet cell autoantigen ICA69, C-terminal domain BAR_3 PF16746.5 RJW60792.1 - 0.025 14.3 4.2 0.049 13.3 4.2 1.5 1 0 0 1 1 1 0 BAR domain of APPL family ACPS PF01648.20 RJW60792.1 - 0.1 12.8 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily SATase_N PF06426.14 RJW60792.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal PK PF00224.21 RJW60795.1 - 2.1e-158 526.8 0.1 2.7e-158 526.4 0.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RJW60795.1 - 8.1e-32 109.9 0.0 1.6e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RJW60795.1 - 0.0039 16.3 1.1 0.031 13.4 0.1 2.2 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 RJW60795.1 - 0.1 11.6 2.7 0.35 9.8 0.0 2.5 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain MBT PF02820.18 RJW60796.1 - 6.5e-28 96.9 0.0 7.1e-21 74.3 0.0 2.5 2 0 0 2 2 2 2 mbt repeat SAM_1 PF00536.30 RJW60796.1 - 4.5e-06 27.0 0.1 8.4e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 RJW60796.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Membralin PF09746.9 RJW60797.1 - 2.3e-85 287.0 4.2 2.3e-63 214.5 1.1 3.1 3 0 0 3 3 3 3 Tumour-associated protein EFTUD2 PF16004.5 RJW60797.1 - 0.29 11.7 1.6 0.38 11.3 0.0 1.8 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus UNC45-central PF11701.8 RJW60798.1 - 3.5e-20 72.5 0.0 2.2e-19 69.9 0.0 2.5 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central TPR_1 PF00515.28 RJW60798.1 - 2.1e-12 46.3 8.1 0.00012 21.7 0.3 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW60798.1 - 8.4e-12 44.3 6.5 5.4e-05 23.0 0.4 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RJW60798.1 - 2e-08 33.8 8.0 0.0064 16.6 0.3 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW60798.1 - 1.3e-07 31.8 2.2 2e-05 24.8 0.2 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW60798.1 - 1.6e-07 31.8 3.4 1.1e-05 26.0 0.8 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW60798.1 - 3e-05 23.7 1.6 1.3 9.3 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW60798.1 - 3.2e-05 24.0 3.2 0.0081 16.5 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW60798.1 - 3.2e-05 24.0 0.4 0.00018 21.6 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW60798.1 - 0.00019 22.0 5.0 0.96 10.5 0.8 4.4 1 1 2 3 3 3 3 Tetratricopeptide repeat DUF4919 PF16266.5 RJW60798.1 - 0.00039 20.4 0.1 0.00086 19.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4919) HEAT_2 PF13646.6 RJW60798.1 - 0.00061 20.1 4.7 0.37 11.2 0.0 6.3 8 0 0 8 8 7 1 HEAT repeats TPR_11 PF13414.6 RJW60798.1 - 0.00094 18.8 0.5 0.00094 18.8 0.5 2.9 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.6 RJW60798.1 - 0.0012 19.4 5.4 0.064 13.9 1.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW60798.1 - 0.002 18.3 7.8 0.017 15.4 0.2 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 HEAT PF02985.22 RJW60798.1 - 0.011 15.9 0.6 6.2 7.4 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat Fis1_TPR_C PF14853.6 RJW60798.1 - 0.027 14.6 1.8 0.77 9.9 0.6 2.9 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 RJW60798.1 - 0.067 13.7 10.6 0.063 13.8 2.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 RJW60798.1 - 0.18 10.7 0.4 0.33 9.9 0.4 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) bZIP_1 PF00170.21 RJW60799.1 - 1.5e-13 50.6 15.1 2.5e-13 49.9 15.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RJW60799.1 - 9.6e-06 25.6 13.4 1.9e-05 24.6 13.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RJW60799.1 - 0.00035 21.0 10.8 0.00065 20.2 10.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor TolA_bind_tri PF16331.5 RJW60799.1 - 0.63 10.2 4.7 0.4 10.8 2.4 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation Herpes_capsid PF06112.11 RJW60799.1 - 2.1 8.4 26.7 0.14 12.2 0.2 3.9 4 0 0 4 4 4 0 Gammaherpesvirus capsid protein HEAT PF02985.22 RJW60800.1 - 1.2e-08 34.5 1.0 0.47 10.9 0.0 8.0 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 RJW60800.1 - 3.7e-07 30.3 5.7 0.22 11.6 0.1 5.7 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RJW60800.1 - 0.00011 22.5 0.9 11 6.5 0.0 5.9 4 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 RJW60800.1 - 0.012 16.1 12.1 8.2 7.1 0.9 7.3 7 0 0 7 7 7 0 HEAT-like repeat FANCI_S3 PF14677.6 RJW60800.1 - 0.097 12.4 1.1 23 4.6 0.1 3.8 3 0 0 3 3 3 0 FANCI solenoid 3 TPT PF03151.16 RJW60801.1 - 2.8e-23 82.7 12.8 3.6e-23 82.3 12.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 RJW60801.1 - 7.9e-10 38.4 18.9 1e-09 38.0 18.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RJW60801.1 - 6.6e-08 32.8 28.4 7.4e-05 22.9 9.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family GT87 PF09594.10 RJW60801.1 - 0.033 13.9 6.4 0.16 11.6 0.1 2.7 1 1 1 2 2 2 0 Glycosyltransferase family 87 DUF2809 PF10990.8 RJW60801.1 - 0.35 11.6 7.8 1.3 9.7 0.0 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF2809) GPS PF01825.21 RJW60802.1 - 0.0013 19.2 0.6 0.0038 17.7 0.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif 7tm_2 PF00002.24 RJW60802.1 - 0.073 12.4 8.4 0.11 11.8 8.4 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) COG4 PF08318.12 RJW60804.1 - 6.7e-73 245.7 1.6 1.2e-72 244.8 1.6 1.4 1 0 0 1 1 1 1 COG4 transport protein RVT_1 PF00078.27 RJW60804.1 - 8.5e-48 162.8 1.6 1.7e-44 152.0 0.0 4.0 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) Sec10 PF07393.11 RJW60804.1 - 1.4e-10 40.3 0.5 3e-10 39.2 0.1 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec10 RINT1_TIP1 PF04437.13 RJW60804.1 - 0.0018 17.2 1.1 0.0034 16.3 0.3 1.8 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DIL PF01843.19 RJW60804.1 - 0.0033 17.7 2.7 0.0058 16.9 0.1 2.9 2 0 0 2 2 2 1 DIL domain Corazonin PF17308.2 RJW60804.1 - 0.1 13.0 1.6 0.43 10.9 0.3 2.6 3 0 0 3 3 3 0 Pro-corazonin Cas6 PF09559.10 RJW60804.1 - 0.17 11.9 1.4 0.54 10.2 0.2 2.2 2 0 0 2 2 2 0 Cas6 Crispr DNA_pol_B PF00136.21 RJW60805.1 - 5.5e-16 58.3 0.0 6.1e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_2 PF03175.13 RJW60805.1 - 0.068 12.0 0.1 0.083 11.7 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral E3_UbLigase_R4 PF13764.6 RJW60806.1 - 2.3e-77 261.0 0.0 1.4e-46 159.1 0.0 2.0 2 0 0 2 2 2 2 E3 ubiquitin-protein ligase UBR4 DnaJ PF00226.31 RJW60806.1 - 0.00019 21.5 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 RJW60806.1 - 0.00033 20.7 0.0 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 Pam16 Pkinase_Tyr PF07714.17 RJW60807.1 - 1.1e-70 237.8 0.0 3.1e-70 236.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW60807.1 - 6e-31 107.8 0.0 1.2e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH3_9 PF14604.6 RJW60807.1 - 2.9e-06 27.0 0.1 5.7e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RJW60807.1 - 1.9e-05 24.2 0.2 3.9e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RJW60807.1 - 0.00011 21.8 0.1 0.00019 21.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain GTPase_binding PF09027.10 RJW60807.1 - 0.00021 21.2 0.1 0.00078 19.4 0.1 2.1 1 0 0 1 1 1 1 GTPase binding DUF1676 PF07898.13 RJW60810.1 - 2.8 8.0 11.3 3.2 7.8 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) NfrA_C PF13283.6 RJW60811.1 - 0.038 13.5 0.0 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage N adsorption protein A C-term CAP_GLY PF01302.25 RJW60812.1 - 2.9e-24 84.9 0.8 4.8e-24 84.2 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 RJW60812.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain zf-UBR PF02207.20 RJW60813.1 - 3.7e-07 30.2 16.7 8.7e-07 29.0 16.7 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) AATF-Che1 PF13339.6 RJW60813.1 - 0.51 11.0 4.9 2.8 8.6 4.9 2.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor KBP_C PF12309.8 RJW60814.1 - 9.5e-45 153.7 0.1 2.2e-44 152.4 0.1 1.7 1 0 0 1 1 1 1 KIF-1 binding protein C terminal TPR_19 PF14559.6 RJW60814.1 - 0.2 12.2 1.2 3.3 8.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW60814.1 - 0.3 11.0 2.6 44 4.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat W2 PF02020.18 RJW60818.1 - 1.7e-18 66.5 1.8 4e-18 65.3 1.8 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon MIF4G PF02854.19 RJW60818.1 - 1.5e-10 41.1 0.0 1.5e-09 37.8 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain TPR_2 PF07719.17 RJW60819.1 - 2e-28 96.1 14.4 7.6e-06 25.7 0.0 7.9 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 RJW60819.1 - 3.2e-28 96.4 16.5 3.3e-06 26.7 0.1 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 RJW60819.1 - 2.3e-23 82.2 9.2 8e-08 32.5 1.2 5.5 5 1 0 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 RJW60819.1 - 4.3e-21 73.3 3.9 0.0092 15.9 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 RJW60819.1 - 6.3e-20 71.6 1.8 1.8e-10 41.3 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW60819.1 - 3e-18 64.4 18.5 0.0061 16.7 0.1 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 RJW60819.1 - 4.9e-15 54.9 9.8 5e-08 32.5 0.2 5.6 4 1 2 6 6 6 4 TPR repeat TPR_19 PF14559.6 RJW60819.1 - 1e-14 54.8 4.1 9.5e-05 22.8 0.7 4.9 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 RJW60819.1 - 1.8e-14 53.3 12.8 0.11 13.2 0.2 8.7 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 RJW60819.1 - 8.4e-13 47.7 8.3 0.091 12.7 0.2 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW60819.1 - 7.7e-11 42.1 10.5 6.3e-09 35.9 3.5 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RJW60819.1 - 9e-10 38.5 3.6 0.45 11.5 0.1 6.7 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 RJW60819.1 - 7.9e-06 25.9 0.0 0.19 11.9 0.4 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 RJW60819.1 - 1.5e-05 24.8 4.1 0.067 12.9 0.8 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 RJW60819.1 - 9.3e-05 22.4 6.1 3.6 7.7 0.1 5.7 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 RJW60819.1 - 0.00028 20.4 1.7 0.39 10.0 0.0 3.5 2 2 0 3 3 3 1 MalT-like TPR region MIT PF04212.18 RJW60819.1 - 0.00044 20.3 3.6 4.5 7.4 0.0 5.1 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 RJW60819.1 - 0.00049 20.3 9.8 0.84 10.2 0.6 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 RJW60819.1 - 0.0026 18.1 3.0 1 9.7 0.1 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 RJW60819.1 - 0.0034 16.8 3.1 0.013 14.9 0.1 2.7 3 0 0 3 3 3 1 Coatomer epsilon subunit DUF3808 PF10300.9 RJW60819.1 - 0.0036 16.1 2.5 0.078 11.7 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_3 PF07720.12 RJW60819.1 - 0.024 14.6 14.0 2.3 8.3 0.2 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.22 RJW60820.1 - 4.7e-31 107.7 0.0 1.9e-14 52.8 0.1 4.9 3 1 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RJW60820.1 - 3.2e-22 78.8 0.0 2.2e-17 62.9 0.0 3.2 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 RJW60820.1 - 0.00013 21.9 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 RJW60820.1 - 0.051 12.5 0.0 0.79 8.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) Nrap_D3 PF17404.2 RJW60821.1 - 0.007 16.5 0.3 1.5 8.9 0.0 2.2 2 0 0 2 2 2 2 Nrap protein domain 3 Ycf66_N PF07444.11 RJW60824.1 - 0.012 15.7 2.3 0.012 15.7 2.3 3.2 3 0 0 3 3 3 0 Ycf66 protein N-terminus rve PF00665.26 RJW60825.1 - 8.1e-13 48.6 0.0 1.3e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 RJW60825.1 - 3.7e-09 36.5 0.0 7.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW60825.1 - 2.1e-07 31.2 0.0 4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW60826.1 - 0.00013 21.5 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_Ag35 PF03286.14 RJW60826.1 - 0.19 11.5 1.7 0.35 10.7 1.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Astro_capsid_p PF12226.8 RJW60826.1 - 0.36 9.9 12.7 0.55 9.3 12.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 RJW60826.1 - 5.4 5.1 11.0 7.9 4.5 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family Ion_trans PF00520.31 RJW60827.1 - 1.8e-06 27.4 1.5 2.4e-06 27.0 0.7 1.5 2 0 0 2 2 2 1 Ion transport protein SLAC1 PF03595.17 RJW60827.1 - 0.012 15.0 0.8 0.012 15.0 0.8 1.7 2 0 0 2 2 2 0 Voltage-dependent anion channel DUF3671 PF12420.8 RJW60827.1 - 0.054 13.6 2.1 4.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function RVT_1 PF00078.27 RJW60828.1 - 4.5e-46 157.1 0.0 9.6e-46 156.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) XPG_I PF00867.18 RJW60828.1 - 6.6e-20 71.3 0.0 1.8e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 RJW60828.1 - 1.6e-07 31.8 0.0 3.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 RJW60828.1 - 2.7e-05 23.8 0.1 6.6e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 XPG domain containing SNF2_N PF00176.23 RJW60829.1 - 1.9e-72 243.9 6.3 5.8e-72 242.3 4.8 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 RJW60829.1 - 1.2e-39 134.9 0.6 3.8e-39 133.2 0.6 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 RJW60829.1 - 1.9e-31 109.1 0.2 5.1e-31 107.7 0.2 1.8 1 0 0 1 1 1 1 HAND Helicase_C PF00271.31 RJW60829.1 - 2.9e-18 66.2 0.1 1.4e-17 64.1 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW60829.1 - 2.5e-09 37.4 0.0 7.6e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RJW60829.1 - 3.2e-07 30.3 0.1 1.3e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 RJW60829.1 - 4.8e-06 26.7 0.6 0.0074 16.5 0.0 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain SWI2_SNF2 PF18766.1 RJW60829.1 - 0.0002 21.1 0.1 0.00057 19.6 0.1 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 RJW60829.1 - 0.00026 20.3 0.0 0.00087 18.5 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.6 RJW60829.1 - 0.048 13.7 0.1 0.39 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4800 PF16057.5 RJW60829.1 - 0.11 11.7 2.5 0.091 12.0 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) TPH PF13868.6 RJW60831.1 - 0.037 12.5 18.6 0.046 12.2 18.6 1.1 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain Ras PF00071.22 RJW60832.1 - 2.5e-19 69.4 1.6 3.6e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 RJW60832.1 - 6.6e-10 39.3 0.2 2.3e-09 37.5 0.2 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 RJW60832.1 - 1.3e-06 27.5 0.9 4.1e-06 25.9 0.2 2.4 2 0 0 2 2 2 1 EF hand Arf PF00025.21 RJW60832.1 - 1.8e-06 27.5 0.0 1.8e-06 27.5 0.0 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_5 PF13202.6 RJW60832.1 - 3e-06 26.5 0.3 1.3e-05 24.5 0.3 2.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RJW60832.1 - 9.5e-06 25.2 0.1 4.2e-05 23.2 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 RJW60832.1 - 0.00016 22.1 0.0 0.00016 22.1 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW60832.1 - 0.00025 20.8 1.1 0.0016 18.3 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair DUF2573 PF10835.8 RJW60832.1 - 0.0051 17.1 2.7 0.035 14.4 0.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2573) PRKG1_interact PF15898.5 RJW60832.1 - 0.0059 17.5 12.5 0.0059 17.5 12.5 5.1 3 2 4 7 7 7 1 cGMP-dependent protein kinase interacting domain MMR_HSR1 PF01926.23 RJW60832.1 - 0.03 14.4 0.0 0.16 12.1 0.0 2.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3584 PF12128.8 RJW60832.1 - 0.033 11.7 36.5 0.052 11.1 36.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HSBP1 PF06825.12 RJW60832.1 - 0.14 12.1 4.0 0.15 12.0 0.8 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 RsgA_GTPase PF03193.16 RJW60832.1 - 0.25 11.2 0.0 0.25 11.2 0.0 3.0 2 1 0 2 2 2 0 RsgA GTPase ATP-synt_E_2 PF08112.11 RJW60832.1 - 0.86 9.9 8.1 6.2 7.2 0.6 4.1 2 1 1 3 3 3 0 ATP synthase epsilon subunit AAA_13 PF13166.6 RJW60832.1 - 0.97 8.0 31.9 0.28 9.8 28.1 1.8 1 1 1 2 2 2 0 AAA domain AI-2E_transport PF01594.16 RJW60832.1 - 1.1 8.3 3.6 0.43 9.7 0.1 1.8 2 0 0 2 2 2 0 AI-2E family transporter Bacillus_HBL PF05791.11 RJW60832.1 - 1.3 8.8 16.9 0.33 10.8 7.8 2.7 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 RJW60832.1 - 1.5 9.0 26.8 9.4 6.4 16.2 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 RJW60832.1 - 1.6 8.8 27.4 0.19 11.8 10.8 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) ABC_tran PF00005.27 RJW60832.1 - 1.7 9.2 0.0 1.7 9.2 0.0 3.7 2 1 0 2 2 1 0 ABC transporter Baculo_PEP_C PF04513.12 RJW60832.1 - 3.6 7.6 14.7 1.5 8.8 1.5 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 RJW60832.1 - 6.4 7.5 28.0 2.5 8.8 11.0 4.4 3 1 0 3 3 3 0 SlyX Homeodomain PF00046.29 RJW60833.1 - 1.4e-20 72.8 1.3 2.5e-20 72.1 1.3 1.4 1 0 0 1 1 1 1 Homeodomain Sec1 PF00995.23 RJW60835.1 - 1.5e-95 321.6 0.0 2e-95 321.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Mago-bind PF09282.10 RJW60835.1 - 0.23 11.4 0.9 1.1 9.2 0.3 2.3 2 0 0 2 2 2 0 Mago binding CLASP_N PF12348.8 RJW60836.1 - 5.7e-18 65.3 4.3 2.3e-07 30.6 0.0 5.0 4 2 1 5 5 5 3 CLASP N terminal HEAT_2 PF13646.6 RJW60836.1 - 4.7e-09 36.5 8.2 0.12 12.8 0.0 8.4 5 3 3 8 8 8 3 HEAT repeats Cnd1 PF12717.7 RJW60836.1 - 5.6e-08 33.0 8.8 0.0016 18.5 0.1 6.1 4 3 3 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RJW60836.1 - 3.5e-07 29.9 11.6 2.6 8.6 0.0 8.9 10 0 0 10 10 10 2 HEAT repeat TAN PF11640.8 RJW60836.1 - 2.1e-06 27.9 5.5 0.12 12.5 0.0 4.9 4 1 1 5 5 5 2 Telomere-length maintenance and DNA damage repair Adaptin_N PF01602.20 RJW60836.1 - 4.4e-06 25.5 4.4 0.028 13.0 0.2 3.9 4 0 0 4 4 4 2 Adaptin N terminal region DCB PF16213.5 RJW60836.1 - 0.004 16.8 0.6 0.49 10.0 0.1 3.2 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 NUC173 PF08161.12 RJW60836.1 - 0.02 14.6 0.0 3.2 7.3 0.0 3.6 3 1 0 3 3 3 0 NUC173 domain ASFV_J13L PF05568.11 RJW60836.1 - 0.043 13.6 8.9 0.11 12.2 8.9 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein U3snoRNP10 PF12397.8 RJW60836.1 - 0.055 13.8 2.9 3.2 8.1 0.5 3.4 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 DUF4404 PF14357.6 RJW60836.1 - 0.083 13.5 0.3 0.78 10.4 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) APC_u15 PF16636.5 RJW60836.1 - 0.11 12.9 0.3 0.39 11.2 0.3 1.9 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 MMS19_N PF14500.6 RJW60836.1 - 1.4 8.5 9.0 5.3 6.5 0.0 4.6 5 1 1 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II BcrAD_BadFG PF01869.20 RJW60838.1 - 3.8e-17 62.7 0.2 4.4e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Scramblase PF03803.15 RJW60841.1 - 1.6e-47 161.7 0.1 2e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 Scramblase Scramblase PF03803.15 RJW60842.1 - 4.1e-69 232.2 0.4 5e-69 232.0 0.4 1.0 1 0 0 1 1 1 1 Scramblase LOR PF04525.12 RJW60842.1 - 0.1 12.2 0.0 2.6 7.6 0.0 2.3 1 1 0 1 1 1 0 LURP-one-related ATP-synt_C PF00137.21 RJW60844.1 - 6.7e-35 119.2 20.1 4.6e-21 74.9 8.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 RJW60844.1 - 2.5 8.0 6.4 4.6 7.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) 7tm_1 PF00001.21 RJW60845.1 - 0.033 13.5 2.9 0.056 12.8 2.9 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RRM_1 PF00076.22 RJW60846.1 - 0.0015 18.4 0.0 2.9 7.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5536 PF17688.1 RJW60846.1 - 0.0078 16.1 0.0 5.1 6.9 0.0 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5536) 7tm_1 PF00001.21 RJW60847.1 - 7.8e-31 107.4 4.6 1.1e-30 106.9 4.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RJW60847.1 - 1.8e-05 24.6 3.9 2.4e-05 24.2 3.9 1.2 1 0 0 1 1 1 1 Olfactory receptor FtsX PF02687.21 RJW60847.1 - 0.017 15.5 0.9 0.017 15.5 0.9 2.6 2 1 0 2 2 2 0 FtsX-like permease family WSD PF15613.6 RJW60848.1 - 8.2e-13 48.7 0.1 6.3e-05 23.4 0.1 3.2 2 0 0 2 2 2 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif MBD PF01429.19 RJW60848.1 - 5.4e-09 35.6 0.0 1.5e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Methyl-CpG binding domain DDT PF02791.17 RJW60848.1 - 3.9e-06 27.1 1.8 8.5e-06 26.0 1.8 1.6 1 0 0 1 1 1 1 DDT domain DUF4520 PF15016.6 RJW60848.1 - 0.08 13.0 0.0 0.57 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) AT_hook PF02178.19 RJW60848.1 - 0.2 11.6 2.9 0.66 10.0 2.9 2.0 1 0 0 1 1 1 0 AT hook motif bPH_3 PF14470.6 RJW60849.1 - 0.18 12.2 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain TSGA13 PF14994.6 RJW60850.1 - 0.16 11.4 0.0 0.32 10.3 0.0 1.4 2 0 0 2 2 2 0 Testis-specific gene 13 protein WW PF00397.26 RJW60851.1 - 9.3e-07 28.8 0.4 2.1e-06 27.7 0.4 1.6 1 0 0 1 1 1 1 WW domain Mdv1 PF11542.8 RJW60851.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial division protein 1 RAI16-like PF10257.9 RJW60852.1 - 1.3e-40 139.4 0.5 3.3e-40 138.1 0.5 1.7 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein EGF PF00008.27 RJW60853.1 - 5.2e-66 218.5 261.3 4e-09 36.6 6.8 19.1 17 1 0 18 18 18 16 EGF-like domain hEGF PF12661.7 RJW60853.1 - 4.7e-31 106.3 233.6 5.2e-06 26.9 4.6 20.4 20 2 0 20 20 20 14 Human growth factor-like EGF DSL PF01414.19 RJW60853.1 - 3.4e-14 52.9 8.2 3.4e-14 52.9 8.2 13.6 8 3 3 14 14 14 3 Delta serrate ligand EGF_2 PF07974.13 RJW60853.1 - 7.8e-10 39.0 306.4 0.0035 17.7 7.3 19.8 20 0 0 20 20 20 14 EGF-like domain EGF_CA PF07645.15 RJW60853.1 - 0.0017 18.5 30.2 0.0038 17.4 8.7 19.4 6 3 13 19 19 19 6 Calcium-binding EGF domain EGF_3 PF12947.7 RJW60853.1 - 0.014 15.5 4.1 0.014 15.5 4.1 17.6 13 3 4 17 17 17 0 EGF domain Mon1 PF03164.14 RJW60854.1 - 7.4e-101 338.1 0.1 8.8e-101 337.9 0.1 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 7tm_1 PF00001.21 RJW60855.1 - 4.7e-12 45.8 18.2 4.7e-11 42.5 18.2 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW60855.1 - 8.2e-07 28.6 15.6 0.0064 15.8 12.1 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 RJW60855.1 - 0.024 14.0 8.0 0.067 12.5 8.0 1.7 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 RJW60855.1 - 0.42 10.3 13.0 2.3 7.9 0.4 2.3 2 0 0 2 2 2 0 Olfactory receptor GrpE PF01025.19 RJW60858.1 - 1.4e-44 151.7 0.2 1.9e-44 151.2 0.2 1.1 1 0 0 1 1 1 1 GrpE CLZ PF16526.5 RJW60858.1 - 0.0055 17.0 0.5 0.013 15.9 0.5 1.6 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 RJW60858.1 - 0.016 15.7 0.7 0.025 15.1 0.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region V-ATPase_G_2 PF16999.5 RJW60858.1 - 0.024 15.0 0.8 0.038 14.4 0.8 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit SHE3 PF17078.5 RJW60858.1 - 0.043 13.5 2.8 0.063 13.0 2.8 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 SKA2 PF16740.5 RJW60858.1 - 0.062 13.1 1.1 0.13 12.1 1.1 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF4592 PF15262.6 RJW60861.1 - 0.019 15.6 0.6 7.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) Nrap_D4 PF17405.2 RJW60861.1 - 0.071 12.5 0.4 13 5.1 0.0 2.4 2 0 0 2 2 2 0 Nrap protein nucleotidyltransferase domain 4 UPF0225 PF17775.1 RJW60861.1 - 0.31 11.9 2.9 15 6.5 0.3 2.1 2 0 0 2 2 2 0 UPF0225 domain Lsr2 PF11774.8 RJW60861.1 - 0.32 11.1 3.5 10 6.3 0.4 2.3 2 0 0 2 2 2 0 Lsr2 LCCL PF03815.19 RJW60862.1 - 0.0062 16.6 0.3 0.0089 16.1 0.3 1.3 1 0 0 1 1 1 1 LCCL domain WD40 PF00400.32 RJW60863.1 - 8.9e-30 102.3 23.2 1.8e-05 25.4 0.1 11.7 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW60863.1 - 1.1e-18 67.3 0.0 0.021 15.1 0.1 8.2 5 2 3 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 RJW60863.1 - 5.9e-09 36.2 0.1 1.8e-08 34.6 0.1 1.8 1 1 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 RJW60863.1 - 9.3e-06 25.2 0.0 0.2 10.9 0.1 3.3 3 0 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 RJW60863.1 - 0.0034 16.4 0.2 1.1 8.2 0.0 4.1 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 RJW60863.1 - 0.006 16.3 0.2 0.099 12.3 0.1 2.6 3 0 0 3 3 3 1 TUP1-like enhancer of split eIF2A PF08662.11 RJW60863.1 - 0.0068 16.3 0.0 0.15 12.0 0.0 3.1 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Lgl_C PF08596.10 RJW60863.1 - 0.062 12.0 0.0 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal PD40 PF07676.12 RJW60863.1 - 0.085 12.8 0.0 2.4 8.2 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat COG5 PF10392.9 RJW60863.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 NCD2 PF04905.13 RJW60864.1 - 3.7e-23 81.8 1.1 7.2e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 NAB conserved region 2 (NCD2) NCD1 PF04904.13 RJW60864.1 - 9.4e-19 67.2 0.1 5.2e-18 64.8 0.1 2.2 1 1 0 1 1 1 1 NAB conserved region 1 (NCD1) Rootletin PF15035.6 RJW60864.1 - 0.011 15.7 2.4 0.019 15.0 2.4 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HydF_tetramer PF18133.1 RJW60864.1 - 0.045 13.5 0.2 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Hydrogen maturase F tetramerization domain DHR-2 PF06920.13 RJW60864.1 - 0.064 11.9 1.2 0.18 10.4 0.6 1.8 2 0 0 2 2 2 0 Dock homology region 2 DUF1917 PF08939.10 RJW60864.1 - 0.2 11.5 1.9 0.3 11.0 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) H-kinase_dim PF02895.14 RJW60864.1 - 0.41 11.1 6.3 0.68 10.4 3.8 2.7 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain COMP PF11598.8 RJW60864.1 - 6.4 7.3 6.7 23 5.5 0.8 3.3 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Takusan PF04822.13 RJW60864.1 - 8.6 6.3 11.9 14 5.7 7.6 3.0 2 1 0 2 2 2 0 Takusan DUF1751 PF08551.10 RJW60867.1 - 0.0029 18.1 7.1 0.0041 17.6 5.7 2.0 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Scramblase PF03803.15 RJW60868.1 - 4.6e-72 241.9 0.9 5.4e-72 241.7 0.9 1.0 1 0 0 1 1 1 1 Scramblase SHR-BD PF06650.12 RJW60868.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 SHR-binding domain of vacuolar-sorting associated protein 13 FCH PF00611.23 RJW60870.1 - 5.9e-14 52.1 2.3 2.5e-13 50.1 0.4 2.9 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 RJW60870.1 - 7.1e-13 48.2 0.2 1.3e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RJW60870.1 - 9.2e-12 44.4 0.1 1.6e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RJW60870.1 - 1.7e-05 24.4 0.1 3.7e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain NOPS PF08075.11 RJW60870.1 - 0.088 13.0 0.8 0.26 11.5 0.1 2.2 2 0 0 2 2 2 0 NOPS (NUC059) domain Asp PF00026.23 RJW60871.1 - 9.4e-42 143.5 0.1 6.9e-24 84.8 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW60871.1 - 1e-07 32.4 0.0 2.2e-06 28.0 0.0 2.1 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RJW60871.1 - 0.0018 18.1 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Ig_Tie2_1 PF10430.9 RJW60871.1 - 0.079 13.4 0.0 1.2 9.6 0.0 2.2 1 1 0 2 2 2 0 Tie-2 Ig-like domain 1 TFIIB PF00382.19 RJW60873.1 - 2.5e-27 94.7 0.1 1.9e-15 56.6 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 RJW60873.1 - 3.3e-21 75.5 1.3 1.3e-20 73.6 1.3 2.1 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 RJW60873.1 - 1.8e-08 33.7 3.7 4e-08 32.6 3.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 RJW60873.1 - 0.0077 16.0 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RJW60873.1 - 0.069 13.2 0.2 7.8 6.6 0.0 3.0 3 0 0 3 3 3 0 Cyclin, C-terminal domain BRE1 PF08647.11 RJW60875.1 - 0.0079 16.3 3.0 0.0079 16.3 3.0 2.1 2 0 0 2 2 2 1 BRE1 E3 ubiquitin ligase SKA2 PF16740.5 RJW60875.1 - 0.024 14.4 6.8 0.044 13.6 6.8 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 AAA_23 PF13476.6 RJW60875.1 - 0.053 14.0 9.8 0.084 13.4 9.8 1.2 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 RJW60875.1 - 0.055 13.5 3.6 0.089 12.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cauli_DNA-bind PF03310.13 RJW60875.1 - 0.074 13.1 1.0 0.19 11.8 0.2 1.8 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein Fib_alpha PF08702.10 RJW60875.1 - 0.18 12.0 4.7 0.32 11.2 4.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V-SNARE PF05008.15 RJW60875.1 - 0.23 11.8 7.7 0.94 9.9 2.3 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Noelin-1 PF12308.8 RJW60875.1 - 0.25 11.4 6.3 2.7 8.0 3.8 2.2 1 1 1 2 2 2 0 Neurogenesis glycoprotein FapA PF03961.13 RJW60875.1 - 5.3 5.5 6.8 7.8 5.0 6.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TspO_MBR PF03073.15 RJW60876.1 - 0.00029 20.9 1.6 0.00029 20.9 1.6 2.0 2 0 0 2 2 2 1 TspO/MBR family GWT1 PF06423.12 RJW60876.1 - 0.89 9.7 6.1 0.22 11.7 1.0 2.5 2 1 0 2 2 2 0 GWT1 DUF4817 PF16087.5 RJW60877.1 - 2e-16 59.5 0.0 9.1e-16 57.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) HTH_IclR PF09339.10 RJW60877.1 - 0.012 15.3 0.1 0.1 12.4 0.1 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain MCM2_N PF12619.8 RJW60878.1 - 2.6 8.3 8.1 0.43 10.9 3.5 1.9 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 BcrAD_BadFG PF01869.20 RJW60879.1 - 1.8e-07 30.9 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family CDP-OH_P_transf PF01066.21 RJW60880.1 - 4.8e-17 62.5 0.3 4.8e-17 62.5 0.3 2.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gag_p12 PF01141.18 RJW60881.1 - 0.044 14.1 0.1 0.061 13.7 0.1 1.2 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 HA2 PF04408.23 RJW60883.1 - 4.5e-21 75.2 0.0 4.5e-21 75.2 0.0 3.8 5 1 0 5 5 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RJW60883.1 - 2e-14 53.7 0.0 5.1e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RJW60883.1 - 1.9e-13 50.7 0.0 4.6e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DSS1_SEM1 PF05160.13 RJW60883.1 - 8.8e-09 35.3 14.6 8.8e-09 35.3 14.6 3.2 3 1 0 3 3 1 1 DSS1/SEM1 family AAA_22 PF13401.6 RJW60883.1 - 2.2e-06 28.0 0.0 6.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RJW60883.1 - 3.4e-05 24.2 0.1 0.00015 22.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 RJW60883.1 - 0.00013 21.3 0.0 0.00044 19.6 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 RJW60883.1 - 0.00015 21.5 0.0 0.00042 20.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain DEAD PF00270.29 RJW60883.1 - 0.00069 19.4 0.1 0.0021 17.8 0.1 1.9 2 1 0 2 2 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 RJW60883.1 - 0.0024 17.0 0.0 0.006 15.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 RJW60883.1 - 0.0062 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 RJW60883.1 - 0.035 13.5 0.0 0.096 12.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 RJW60883.1 - 0.042 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_33 PF13671.6 RJW60883.1 - 0.042 14.0 0.1 0.29 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RJW60883.1 - 0.046 14.1 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 RJW60883.1 - 0.069 13.7 0.0 0.069 13.7 0.0 2.9 4 0 0 4 4 3 0 ABC transporter AAA_23 PF13476.6 RJW60883.1 - 0.16 12.5 0.0 0.16 12.5 0.0 4.4 4 0 0 4 4 4 0 AAA domain DCX PF03607.17 RJW60884.1 - 2.2e-12 46.9 0.2 0.2 11.8 0.0 6.1 5 0 0 5 5 5 5 Doublecortin Ricin_B_lectin PF00652.22 RJW60884.1 - 5e-06 26.8 0.3 0.35 11.1 0.0 3.7 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain KHA PF11834.8 RJW60884.1 - 0.04 14.0 0.0 12 6.0 0.0 3.2 3 0 0 3 3 3 0 KHA, dimerisation domain of potassium ion channel DUF1043 PF06295.12 RJW60884.1 - 0.57 10.2 6.0 2.5 8.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) HEAT PF02985.22 RJW60885.1 - 0.0002 21.4 3.5 0.7 10.3 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 RJW60885.1 - 0.00051 19.7 3.6 1.3 8.5 0.0 4.8 6 0 0 6 6 6 1 CLASP N terminal Adaptin_N PF01602.20 RJW60885.1 - 0.0014 17.2 3.1 0.51 8.8 0.0 3.6 3 1 0 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.7 RJW60885.1 - 0.0033 17.5 0.1 1.4 9.0 0.0 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 RJW60885.1 - 0.035 13.8 1.4 0.077 12.7 1.4 1.5 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 RJW60885.1 - 0.043 14.3 0.2 64 4.2 0.0 4.2 3 0 0 3 3 3 0 HEAT-like repeat RVT_1 PF00078.27 RJW60888.1 - 0.0017 17.9 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3084 PF11283.8 RJW60888.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) RT_RNaseH_2 PF17919.1 RJW60889.1 - 5.4e-05 23.2 0.1 0.0002 21.3 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW60889.1 - 0.00012 22.3 0.3 0.00071 19.8 0.1 2.3 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase Mid2 PF04478.12 RJW60889.1 - 0.097 12.5 0.2 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Tfb4 PF03850.14 RJW60890.1 - 1.7e-68 231.1 0.0 4.1e-67 226.6 0.0 2.2 1 1 0 1 1 1 1 Transcription factor Tfb4 FtsJ PF01728.19 RJW60890.1 - 9.4e-32 110.5 0.0 1.7e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.23 RJW60890.1 - 2.3e-12 46.6 2.5 4.7e-12 45.6 2.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RJW60890.1 - 5e-05 23.3 0.2 0.00011 22.2 0.2 1.6 1 0 0 1 1 1 1 G-patch domain Kinesin PF00225.23 RJW60891.1 - 1.1e-116 389.5 0.0 2.8e-116 388.1 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW60891.1 - 1.7e-25 89.7 0.0 5.5e-25 88.1 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding UPF0242 PF06785.11 RJW60891.1 - 2.5e-05 24.5 6.5 2.5e-05 24.5 6.5 2.8 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Kinesin_assoc PF16183.5 RJW60891.1 - 0.0053 16.9 6.8 0.15 12.2 6.8 2.7 1 1 0 1 1 1 1 Kinesin-associated AAA_22 PF13401.6 RJW60891.1 - 0.0074 16.6 6.2 0.099 12.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 RJW60891.1 - 0.0075 16.7 3.3 0.027 14.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 RJW60891.1 - 0.12 12.3 0.3 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 NACHT domain DUF4407 PF14362.6 RJW60891.1 - 2.5 7.4 12.0 0.22 10.8 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Urocanase PF01175.18 RJW60892.1 - 1.6e-80 269.7 0.0 2.9e-80 268.9 0.0 1.4 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 RJW60892.1 - 3.2e-79 264.9 0.2 5.5e-79 264.2 0.2 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase_N PF17391.2 RJW60892.1 - 1.3e-49 167.1 0.1 3.8e-49 165.6 0.0 1.8 2 0 0 2 2 2 1 Urocanase N-terminal domain Pepsin-I3 PF06394.13 RJW60892.1 - 0.08 13.2 0.1 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Fer4_20 PF14691.6 RJW60894.1 - 1.1e-32 112.1 0.3 1.3e-32 111.9 0.3 1.1 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_10 PF13237.6 RJW60894.1 - 0.36 11.0 9.1 2.7 8.2 9.3 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain ADK PF00406.22 RJW60895.1 - 8e-34 116.9 0.0 4e-23 82.2 0.0 3.1 2 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 RJW60895.1 - 3.1e-19 69.7 0.0 1.2e-07 32.2 0.0 3.4 3 0 0 3 3 3 3 AAA domain AAA_18 PF13238.6 RJW60895.1 - 1.9e-06 28.4 0.0 0.00011 22.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RJW60895.1 - 7.5e-06 26.2 0.0 3.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RJW60895.1 - 0.00073 19.6 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 RJW60895.1 - 0.0011 17.9 0.1 0.0083 15.1 0.0 1.9 2 0 0 2 2 2 1 PrkA AAA domain Cytidylate_kin PF02224.18 RJW60895.1 - 0.0016 18.2 0.0 0.01 15.6 0.0 2.2 3 0 0 3 3 3 1 Cytidylate kinase SKI PF01202.22 RJW60895.1 - 0.0052 16.9 0.0 1.4 9.1 0.0 3.6 4 0 0 4 4 4 1 Shikimate kinase AAA_22 PF13401.6 RJW60895.1 - 0.023 15.0 0.0 0.065 13.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Cytidylate_kin2 PF13189.6 RJW60895.1 - 0.033 14.3 0.0 4.2 7.4 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase-like family Sigma54_activ_2 PF14532.6 RJW60895.1 - 0.035 14.2 0.0 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Dpy-30 PF05186.13 RJW60895.1 - 0.037 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Dpy-30 motif RuvB_N PF05496.12 RJW60895.1 - 0.037 13.8 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 RJW60895.1 - 0.049 14.2 0.0 0.56 10.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter dNK PF01712.19 RJW60895.1 - 0.068 13.0 0.0 2.5 7.9 0.0 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase Zeta_toxin PF06414.12 RJW60895.1 - 0.072 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 RJW60895.1 - 0.095 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RJW60895.1 - 0.097 13.1 0.1 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW60895.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 RJW60895.1 - 0.13 11.9 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA12 PF10443.9 RJW60895.1 - 0.18 10.5 0.0 0.34 9.6 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein AAA_8 PF12780.7 RJW60895.1 - 0.21 10.9 0.0 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 Ank_5 PF13857.6 RJW60896.1 - 0.069 13.5 0.2 8.6 6.8 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) RRM_1 PF00076.22 RJW60897.1 - 3.1e-59 196.7 0.0 6.8e-19 67.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW60897.1 - 5.9e-11 42.1 0.0 0.00015 21.3 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RJW60897.1 - 0.03 14.2 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF726 PF05277.12 RJW60897.1 - 0.051 12.5 0.2 0.095 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) HLH PF00010.26 RJW60899.1 - 2.5e-11 43.4 5.9 4.3e-11 42.6 5.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Trypsin PF00089.26 RJW60900.1 - 3.3e-19 69.6 0.0 5.6e-19 68.8 0.0 1.3 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RJW60900.1 - 8.6e-08 33.2 0.2 2.2e-07 31.9 0.2 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 RJW60901.1 - 4.8e-07 29.5 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW60901.1 - 2.7e-06 27.6 0.1 5.8e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain FYVE_2 PF02318.16 RJW60901.1 - 4.2e-05 23.7 7.9 0.049 13.8 0.0 3.2 3 0 0 3 3 3 2 FYVE-type zinc finger zf-piccolo PF05715.13 RJW60901.1 - 0.13 12.4 7.0 2.7 8.2 1.4 3.4 3 0 0 3 3 3 0 Piccolo Zn-finger Homeobox_KN PF05920.11 RJW60902.1 - 4.4e-18 64.9 0.1 1e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RJW60902.1 - 7.5e-07 28.9 0.0 2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 RJW60902.1 - 0.82 10.3 12.5 1.8 9.2 1.8 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF212 PF02681.14 RJW60904.1 - 0.041 14.0 0.4 0.077 13.1 0.2 1.6 1 1 1 2 2 2 0 Divergent PAP2 family YfbU PF03887.14 RJW60906.1 - 0.049 13.6 0.0 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 YfbU domain Peptidase_S9 PF00326.21 RJW60908.1 - 0.031 13.8 0.2 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family WBP-1 PF11669.8 RJW60908.1 - 0.037 14.6 0.4 0.12 13.1 0.0 2.0 2 0 0 2 2 2 0 WW domain-binding protein 1 Adeno_shaft PF00608.17 RJW60909.1 - 0.2 11.5 1.6 1.2 9.0 0.1 2.9 3 0 0 3 3 3 0 Adenoviral fibre protein (repeat/shaft region) MFS_1_like PF12832.7 RJW60910.1 - 7.5e-41 140.3 21.7 9.5e-41 139.9 21.7 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RJW60910.1 - 1.4e-06 27.5 52.4 2.3e-05 23.5 6.5 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RJW60910.1 - 0.00073 18.6 1.9 0.00073 18.6 1.9 2.5 2 1 0 2 2 2 1 Nucleoside H+ symporter fn3 PF00041.21 RJW60911.1 - 0.015 15.6 0.3 1.3 9.4 0.0 3.1 2 1 1 3 3 3 0 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW60911.1 - 0.1 13.1 0.1 0.31 11.6 0.0 1.8 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Proteasome PF00227.26 RJW60912.1 - 9.7e-59 198.0 0.0 1.2e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RJW60912.1 - 6.2e-06 25.8 0.1 1.4e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RuvA_C PF07499.13 RJW60912.1 - 0.0075 16.7 0.1 0.031 14.7 0.0 2.1 2 0 0 2 2 2 1 RuvA, C-terminal domain Hep_core_N PF08290.11 RJW60912.1 - 1.3 9.1 3.5 5.2 7.2 0.6 2.9 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger AhpC-TSA_2 PF13911.6 RJW60913.1 - 2.6e-19 69.4 0.0 3.7e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 RJW60913.1 - 5.1e-08 32.9 0.0 7.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RJW60913.1 - 0.042 13.5 0.0 0.19 11.4 0.0 1.9 1 1 0 1 1 1 0 Redoxin RVT_1 PF00078.27 RJW60914.1 - 2.8e-45 154.6 0.0 6.3e-45 153.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_6 PF13516.6 RJW60914.1 - 0.00015 21.5 9.1 0.7 10.1 0.0 6.2 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 RJW60914.1 - 0.00022 21.6 4.4 2.2 8.8 0.2 4.8 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.33 RJW60914.1 - 0.0024 17.7 0.0 0.012 15.4 0.0 2.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RJW60914.1 - 0.021 14.7 0.6 0.16 11.9 0.0 2.9 3 0 0 3 3 3 0 F-box-like LRR_1 PF00560.33 RJW60914.1 - 0.62 10.8 5.7 63 4.7 0.9 4.8 3 1 0 3 3 3 0 Leucine Rich Repeat zf-LITAF-like PF10601.9 RJW60915.1 - 0.048 13.9 0.7 0.048 13.9 0.7 2.0 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain 7tm_1 PF00001.21 RJW60916.1 - 4.1e-07 29.6 0.2 4.2e-06 26.3 0.0 2.3 1 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Neurensin PF14927.6 RJW60917.1 - 0.073 12.8 1.1 0.73 9.6 0.1 2.3 1 1 1 2 2 2 0 Neurensin Amastin PF07344.11 RJW60917.1 - 0.087 12.7 7.7 0.081 12.8 1.3 2.5 3 0 0 3 3 3 0 Amastin surface glycoprotein Tetraspanin PF00335.20 RJW60917.1 - 0.12 12.0 4.6 2 8.1 0.2 2.7 3 0 0 3 3 3 0 Tetraspanin family FYVE_2 PF02318.16 RJW60918.1 - 0.00036 20.7 0.2 0.00067 19.9 0.2 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger PYC_OADA PF02436.18 RJW60918.1 - 0.061 13.1 0.2 0.086 12.6 0.2 1.2 1 0 0 1 1 1 0 Conserved carboxylase domain Ribosomal_L1 PF00687.21 RJW60919.1 - 5.2e-10 39.4 0.0 6.9e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ECF_trnsprt PF12822.7 RJW60922.1 - 1.3 9.2 13.0 4.3e+02 0.9 13.0 2.9 1 1 0 1 1 1 0 ECF transporter, substrate-specific component C2 PF00168.30 RJW60923.1 - 4.7e-13 49.3 0.1 7.1e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 C2 domain DUF2974 PF11187.8 RJW60924.1 - 0.073 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Radial_spoke PF04712.12 RJW60925.1 - 2.1e-124 416.2 7.6 2.1e-124 416.2 7.6 1.6 1 1 1 2 2 2 1 Radial spokehead-like protein C2-set_2 PF08205.12 RJW60925.1 - 0.037 14.1 0.4 0.089 12.9 0.4 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ribosomal_S17e PF00833.18 RJW60926.1 - 5.8e-52 174.8 1.1 1.2e-51 173.7 1.1 1.6 1 0 0 1 1 1 1 Ribosomal S17 NUC153 PF08159.12 RJW60927.1 - 0.009 15.8 0.8 0.021 14.6 0.8 1.6 1 0 0 1 1 1 1 NUC153 domain RRM_1 PF00076.22 RJW60927.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1_like PF12832.7 RJW60928.1 - 6.8e-39 133.8 0.0 1.6e-38 132.6 0.0 1.6 1 1 1 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 RJW60928.1 - 1.2e-07 31.0 45.1 0.001 18.1 21.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily RVT_1 PF00078.27 RJW60929.1 - 1.1e-30 106.8 0.0 2.2e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Xpo1 PF08389.12 RJW60929.1 - 2.2e-05 24.6 5.1 0.044 13.8 0.0 4.1 3 1 1 4 4 4 3 Exportin 1-like protein SIR2 PF02146.17 RJW60930.1 - 3.2e-43 147.7 0.0 7.8e-43 146.4 0.0 1.7 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.16 RJW60930.1 - 0.017 14.1 0.1 0.24 10.3 0.1 2.0 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit Aminotran_5 PF00266.19 RJW60931.1 - 4.3e-30 104.9 0.0 1.7e-16 60.1 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-V ATP_bind_3 PF01171.20 RJW60931.1 - 2.9e-10 40.2 0.2 4.6e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 PP-loop family DUF2045 PF09741.9 RJW60932.1 - 5.1e-58 196.2 0.0 6.8e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) HSP20 PF00011.21 RJW60933.1 - 3.7e-26 91.2 0.0 6.6e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RJW60933.1 - 1.8e-07 30.6 0.0 6.7e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA PGP_phosphatase PF09419.10 RJW60934.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Mitochondrial PGP phosphatase DEAD PF00270.29 RJW60937.1 - 5.5e-46 156.5 0.0 2.2e-45 154.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW60937.1 - 5.1e-27 94.4 0.0 1.5e-26 92.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW60937.1 - 0.00062 19.8 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_L34e PF01199.18 RJW60938.1 - 1.9e-39 133.9 10.1 3e-39 133.2 10.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e 2-oxoacid_dh PF00198.23 RJW60939.1 - 9.6e-77 257.6 0.0 1.3e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 RJW60939.1 - 3.3e-16 59.3 0.2 1.1e-15 57.7 0.2 1.9 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl PF00364.22 RJW60939.1 - 1.2e-11 44.2 0.0 2.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF247 PF03140.15 RJW60939.1 - 0.13 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function UAA PF08449.11 RJW60943.1 - 3.7e-63 213.5 29.1 7.5e-62 209.2 29.1 2.2 1 1 0 1 1 1 1 UAA transporter family Ribosomal_S19e PF01090.19 RJW60944.1 - 3.9e-18 65.5 0.1 4.1e-18 65.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ocnus PF05005.15 RJW60944.1 - 0.028 14.6 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) RVT_1 PF00078.27 RJW60946.1 - 5.9e-09 35.8 0.0 8.3e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP PF00188.26 RJW60948.1 - 2.6e-11 44.5 0.0 7e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Mucin PF01456.17 RJW60948.1 - 0.029 14.4 46.9 0.043 13.8 46.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med13_C PF06333.12 RJW60948.1 - 0.13 11.5 10.9 0.14 11.4 10.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain MGC-24 PF05283.11 RJW60948.1 - 1.5 9.2 19.7 2.8 8.4 19.7 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PTS_EIIC PF02378.18 RJW60949.1 - 0.042 12.9 0.2 0.054 12.5 0.2 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC HMG-CoA_red PF00368.18 RJW60950.1 - 1.7e-119 399.1 0.0 2.4e-119 398.6 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Peptidase_M41 PF01434.18 RJW60950.1 - 2.1e-59 200.6 0.0 3.2e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 RJW60950.1 - 5.7e-45 153.0 0.0 1.1e-44 152.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW60950.1 - 3.7e-12 45.8 0.5 3.7e-12 45.8 0.5 2.3 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 RJW60950.1 - 4.8e-08 33.3 0.0 6.2e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 RJW60950.1 - 0.0022 18.0 0.1 0.013 15.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 RJW60950.1 - 0.011 15.0 0.1 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 RJW60950.1 - 0.04 14.0 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RJW60950.1 - 0.044 14.1 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 RJW60950.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain zf-MIZ PF02891.20 RJW60952.1 - 5.4e-10 38.9 0.2 1.4e-09 37.5 0.2 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger WD40 PF00400.32 RJW60954.1 - 1.6e-44 149.0 5.6 3.2e-09 37.2 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW60954.1 - 1.4e-16 60.6 0.0 0.00019 21.6 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW60954.1 - 7.4e-07 29.2 0.0 0.00074 19.5 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RJW60954.1 - 8.9e-05 21.6 0.3 0.14 11.1 0.0 4.1 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 RJW60954.1 - 0.016 13.8 0.0 0.13 10.7 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 RJW60954.1 - 0.12 11.0 0.3 66 1.9 0.0 3.7 1 1 3 5 5 5 0 Nucleoporin Nup120/160 Biopterin_H PF00351.21 RJW60958.1 - 4.2e-111 371.2 0.2 6e-111 370.7 0.2 1.2 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase HlyIII PF03006.20 RJW60959.1 - 8.1e-36 123.8 18.6 8.1e-36 123.8 18.6 1.6 2 0 0 2 2 2 1 Haemolysin-III related CW_7 PF08230.11 RJW60959.1 - 0.07 12.9 0.1 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 CW_7 repeat ORF11CD3 PF10549.9 RJW60963.1 - 0.19 11.9 0.1 11 6.2 0.0 2.2 2 0 0 2 2 2 0 ORF11CD3 domain Band_7 PF01145.25 RJW60965.1 - 8.9e-31 107.3 0.2 1.3e-30 106.8 0.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 RJW60965.1 - 0.00031 20.5 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 RJW60965.1 - 0.15 12.5 0.3 0.31 11.5 0.3 1.5 1 0 0 1 1 1 0 Phage protein Gp68 Hep_59 PF07052.11 RJW60966.1 - 0.094 13.5 0.1 0.094 13.5 0.1 2.5 2 1 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 DUF745 PF05335.13 RJW60967.1 - 0.026 14.2 0.5 0.026 14.2 0.5 6.5 4 2 2 6 6 6 0 Protein of unknown function (DUF745) MCPsignal PF00015.21 RJW60967.1 - 1.4 8.7 10.0 7.6 6.3 0.1 3.8 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RNB PF00773.19 RJW60968.1 - 8.3e-71 239.0 0.0 2.8e-70 237.3 0.0 1.7 1 1 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 RJW60968.1 - 1.9e-11 43.8 0.0 5.4e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 RJW60968.1 - 4.3e-07 30.0 0.1 0.036 14.3 0.0 2.6 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 RJW60968.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain OB_RNB PF08206.11 RJW60968.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain bZIP_2 PF07716.15 RJW60969.1 - 1.7e-07 31.2 4.9 2.7e-07 30.6 2.9 2.2 2 0 0 2 2 2 1 Basic region leucine zipper UPF0184 PF03670.13 RJW60969.1 - 0.029 14.8 0.8 0.063 13.7 0.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF1910 PF08928.10 RJW60969.1 - 0.036 14.1 0.3 0.045 13.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) DUF883 PF05957.13 RJW60969.1 - 0.95 10.1 4.9 0.76 10.4 0.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ldl_recept_a PF00057.18 RJW60970.1 - 1.1e-06 28.7 8.1 2.1e-06 27.9 8.1 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A HEAT PF02985.22 RJW60971.1 - 1.2e-20 71.9 12.7 2.6e-06 27.2 0.0 9.6 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 RJW60971.1 - 3.3e-20 72.2 12.0 1.8e-12 47.5 0.1 7.1 7 0 0 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 RJW60971.1 - 8.7e-10 38.9 2.8 0.00022 21.5 0.0 6.5 4 2 2 7 7 7 3 HEAT repeats IBN_N PF03810.19 RJW60971.1 - 4.6e-09 36.1 0.5 1.1e-07 31.7 0.1 3.1 2 1 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 RJW60971.1 - 1.8e-08 33.4 1.4 0.017 13.7 0.0 3.5 3 0 0 3 3 3 2 Adaptin N terminal region Arm PF00514.23 RJW60971.1 - 9e-08 31.9 8.3 0.044 13.9 0.0 6.1 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 RJW60971.1 - 2.5e-05 24.4 3.5 0.14 12.2 0.0 5.2 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RJW60971.1 - 6.3e-05 23.5 0.6 0.4 11.3 0.1 4.3 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 RJW60971.1 - 0.00015 21.1 0.6 0.0035 16.6 0.0 3.2 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 RJW60971.1 - 0.0022 17.6 3.2 3.6 7.1 0.0 4.5 5 1 1 6 6 6 2 CLASP N terminal Proteasom_PSMB PF10508.9 RJW60971.1 - 0.017 13.6 0.3 0.15 10.5 0.0 2.3 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit K1 PF02960.14 RJW60971.1 - 0.15 12.2 1.3 25 5.0 0.2 3.0 2 1 1 3 3 3 0 K1 glycoprotein Xpo1 PF08389.12 RJW60971.1 - 0.55 10.3 4.3 25 4.9 0.1 4.6 4 2 1 5 5 5 0 Exportin 1-like protein WD40 PF00400.32 RJW60972.1 - 1.8e-07 31.7 8.9 0.3 12.0 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW60972.1 - 0.0011 19.2 0.0 1.7 9.0 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Proteasome PF00227.26 RJW60973.1 - 3e-09 36.6 0.0 4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 RJW60973.1 - 4.7e-05 22.7 0.6 7.5e-05 22.1 0.6 1.2 1 0 0 1 1 1 1 Proteasome beta subunits C terminal tRNA-synt_1b PF00579.25 RJW60975.1 - 1.7e-43 149.1 0.0 2.2e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CRAL_TRIO PF00650.20 RJW60980.1 - 5.9e-37 126.8 0.0 8.6e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 RJW60980.1 - 3.7e-06 27.5 0.0 6.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 RJW60980.1 - 0.2 11.9 0.1 0.41 10.9 0.1 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain Cyt-b5 PF00173.28 RJW60981.1 - 3.4e-09 36.7 0.0 4.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CD34_antigen PF06365.12 RJW60981.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4381 PF14316.6 RJW60981.1 - 0.094 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) OapA_N PF08525.11 RJW60982.1 - 6.8 6.8 5.5 1.6 8.8 0.2 2.1 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif DUF1194 PF06707.11 RJW60983.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) MARVEL PF01284.23 RJW60983.1 - 0.25 11.3 9.4 1.7 8.6 3.4 2.8 2 0 0 2 2 2 0 Membrane-associating domain HC2 PF07382.11 RJW60985.1 - 2.9e-10 40.6 28.9 1.4e-09 38.3 28.9 1.8 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Keratin_B2_2 PF13885.6 RJW60985.1 - 0.1 12.5 16.2 41 4.2 3.2 4.6 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein RVT_1 PF00078.27 RJW60986.1 - 7.7e-07 28.8 0.0 4.1e-06 26.5 0.0 2.1 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MULE PF10551.9 RJW60986.1 - 0.058 13.8 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 MULE transposase domain 7tm_1 PF00001.21 RJW60987.1 - 1e-11 44.7 18.0 1.4e-11 44.3 18.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MRP-L47 PF06984.13 RJW60988.1 - 6.3e-32 109.6 2.4 1.6e-31 108.2 2.4 1.7 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GCR1_C PF12550.8 RJW60988.1 - 0.096 13.0 5.6 4.8 7.6 0.2 2.4 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes POT1 PF02765.17 RJW60989.1 - 0.14 12.0 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 WD40 PF00400.32 RJW60991.1 - 1.4e-16 60.5 13.4 0.00055 20.7 0.3 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW60991.1 - 0.0066 16.7 0.0 3.2 8.1 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Asp_protease PF09668.10 RJW60994.1 - 1.2e-52 176.9 0.0 1.8e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW60994.1 - 7.5e-19 68.1 0.0 1.6e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RJW60994.1 - 1.3e-08 35.3 0.0 2.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 RJW60994.1 - 2.2e-06 27.5 0.0 6.5e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease ubiquitin PF00240.23 RJW60994.1 - 2.5e-05 23.9 0.0 5.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA_4 PF14555.6 RJW60994.1 - 0.00023 20.9 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain RVP PF00077.20 RJW60994.1 - 0.00078 19.7 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease CysA_C_terminal PF17850.1 RJW60994.1 - 0.076 13.6 0.2 0.27 11.9 0.0 1.9 2 0 0 2 2 2 0 CysA C-terminal regulatory domain Hyd_WA PF06462.12 RJW60995.1 - 7e-05 22.7 0.1 0.00086 19.2 0.0 2.8 2 0 0 2 2 2 1 Propeller GYF PF02213.16 RJW60996.1 - 6.7e-13 48.1 0.0 1.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 GYF domain tRNA-synt_2 PF00152.20 RJW60998.1 - 2e-67 227.5 0.0 3.5e-67 226.7 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RJW60998.1 - 9.5e-08 31.9 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RJW60998.1 - 0.0022 17.5 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 RJW60998.1 - 0.091 12.7 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Ank_4 PF13637.6 RJW61000.1 - 3.2e-09 37.1 0.1 8.4e-06 26.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW61000.1 - 3.6e-09 37.1 0.0 8.1e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW61000.1 - 1.1e-07 31.6 0.1 0.27 11.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RJW61000.1 - 3.3e-07 30.4 0.1 2.8e-05 24.3 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RJW61000.1 - 8.1e-05 22.9 1.8 0.36 11.3 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat PDH_E1_M PF17831.1 RJW61000.1 - 0.079 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain ACT PF01842.25 RJW61000.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 ACT domain Arf PF00025.21 RJW61003.1 - 8.5e-54 181.6 0.0 9.7e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RJW61003.1 - 8.4e-15 54.7 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 RJW61003.1 - 3.4e-14 53.1 0.0 4.8e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RJW61003.1 - 2.6e-13 49.9 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 RJW61003.1 - 6.7e-11 41.9 1.6 2.5e-06 26.9 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RJW61003.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RJW61003.1 - 2.3e-09 37.3 0.0 3.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RJW61003.1 - 4.5e-08 32.9 0.1 7.4e-05 22.4 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 RJW61003.1 - 1.8e-05 25.0 0.5 0.00038 20.7 0.4 2.6 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.18 RJW61003.1 - 0.0013 18.3 0.8 0.0045 16.5 0.8 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 RJW61003.1 - 0.0036 17.8 0.1 0.0053 17.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 RJW61003.1 - 0.0089 15.8 0.0 0.24 11.2 0.0 2.2 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 RJW61003.1 - 0.013 15.5 0.2 4.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 RJW61003.1 - 0.014 15.1 0.4 0.099 12.4 0.4 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 RJW61003.1 - 0.077 12.6 0.3 12 5.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 RJW61003.1 - 0.079 12.7 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 RJW61003.1 - 0.088 12.5 0.4 0.34 10.6 0.4 1.9 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 RJW61006.1 - 7.7e-67 225.4 0.0 1.1e-66 224.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61006.1 - 2.4e-29 102.4 0.0 3.6e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW61006.1 - 0.00019 20.5 0.0 0.00056 19.0 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RJW61006.1 - 0.0024 17.2 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 RJW61006.1 - 0.022 13.8 0.1 0.038 13.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 RJW61006.1 - 0.046 13.6 0.1 0.079 12.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Homeodomain PF00046.29 RJW61007.1 - 7.7e-08 32.1 0.4 2.5e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Homeodomain DUF4739 PF15893.5 RJW61007.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) Arrestin_C PF02752.22 RJW61009.1 - 0.094 13.2 15.6 0.022 15.2 10.6 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RJW61009.1 - 0.12 12.4 0.0 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain zf-RING_2 PF13639.6 RJW61010.1 - 8.7e-14 51.6 8.5 1.2e-13 51.1 8.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RJW61010.1 - 4.4e-09 36.2 7.7 6.2e-09 35.7 7.7 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 RJW61010.1 - 5.1e-09 35.7 3.4 5.1e-09 35.7 3.4 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RJW61010.1 - 3.2e-08 33.3 9.2 4.9e-08 32.7 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW61010.1 - 5.9e-08 32.9 9.5 1.4e-07 31.7 9.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RJW61010.1 - 7.4e-08 32.3 2.2 7.4e-08 32.3 2.2 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RJW61010.1 - 1.2e-07 31.5 5.3 1.6e-07 31.1 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW61010.1 - 3.2e-07 30.1 8.5 4.7e-07 29.6 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RJW61010.1 - 2.9e-05 23.8 4.9 7.4e-05 22.5 5.0 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RJW61010.1 - 0.0013 18.7 5.7 0.0031 17.5 5.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RJW61010.1 - 0.0013 18.3 8.3 0.0022 17.6 8.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 RJW61010.1 - 0.035 14.3 4.1 0.055 13.7 4.1 1.4 1 1 0 1 1 1 0 Zinc-ribbon like family RINGv PF12906.7 RJW61010.1 - 0.071 13.2 5.4 0.14 12.3 5.4 1.5 1 1 0 1 1 1 0 RING-variant domain CxC4 PF18717.1 RJW61010.1 - 0.071 13.0 4.1 0.11 12.4 4.1 1.2 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases FANCL_C PF11793.8 RJW61010.1 - 0.078 13.2 7.0 0.45 10.7 7.0 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 RJW61010.1 - 0.08 12.8 3.9 0.14 12.0 3.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 RJW61010.1 - 0.13 12.1 6.1 0.35 10.7 5.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.6 RJW61010.1 - 0.36 11.1 5.7 1.3 9.3 5.7 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3H2C3 PF17122.5 RJW61010.1 - 0.39 10.8 9.3 0.86 9.7 9.3 1.7 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 RJW61010.1 - 0.67 10.2 6.8 1.7 8.8 6.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 RJW61010.1 - 0.7 10.0 7.1 1.9 8.6 7.2 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 RJW61010.1 - 2.3 8.2 7.5 6.6 6.7 7.6 1.7 1 1 1 2 2 2 0 PHD-finger Vps39_2 PF10367.9 RJW61010.1 - 6 7.4 7.0 19 5.7 2.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING-like PF08746.11 RJW61010.1 - 8.6 6.8 9.4 20 5.6 9.5 1.6 1 1 0 1 1 1 0 RING-like domain MCM PF00493.23 RJW61011.1 - 7.4e-99 329.4 0.0 1.1e-98 328.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RJW61011.1 - 4.2e-36 123.6 0.5 7.7e-36 122.7 0.5 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RJW61011.1 - 3.5e-27 94.7 0.9 8.5e-27 93.4 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RJW61011.1 - 5.4e-18 65.5 0.1 1.1e-17 64.5 0.1 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RJW61011.1 - 1.5e-06 27.8 0.0 0.00047 19.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RJW61011.1 - 2e-05 24.6 0.0 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RJW61011.1 - 0.021 14.7 0.0 0.06 13.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RJW61011.1 - 0.05 13.3 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain GKAP PF03359.13 RJW61012.1 - 8.1e-12 45.4 4.3 8.1e-12 45.4 4.3 1.8 1 1 1 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein RNB PF00773.19 RJW61015.1 - 1.1e-91 307.6 0.0 5.2e-71 239.6 0.0 2.1 2 0 0 2 2 2 2 RNB domain Dis3l2_C_term PF17877.1 RJW61015.1 - 4.1e-15 55.9 0.0 9.9e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 RJW61015.1 - 5.2e-13 48.8 0.0 1.3e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 RJW61015.1 - 0.00051 19.8 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Filament PF00038.21 RJW61016.1 - 8.3e-40 137.3 67.8 6.9e-39 134.3 67.8 2.0 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 RJW61016.1 - 7.6e-10 39.1 0.0 1.6e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain Fib_alpha PF08702.10 RJW61016.1 - 0.013 15.7 11.6 0.013 15.7 11.6 5.1 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 RJW61016.1 - 0.42 11.0 70.4 0.74 10.2 32.1 3.6 1 1 2 3 3 3 0 Fez1 GAS PF13851.6 RJW61016.1 - 3.6 6.9 68.8 1.2 8.4 18.6 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 RJW61016.1 - 4.8 6.8 70.8 1.1 8.9 18.3 4.2 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease NFRKB_winged PF14465.6 RJW61016.1 - 7.8 6.8 6.8 7.1 6.9 0.1 3.5 3 0 0 3 3 3 0 NFRKB Winged Helix-like NUDIX PF00293.28 RJW61017.1 - 7.6e-11 42.2 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RVT_1 PF00078.27 RJW61017.1 - 5e-05 22.9 0.0 8.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 RJW61017.1 - 0.28 11.4 6.5 1.2 9.3 0.7 2.8 2 0 0 2 2 2 0 Zinc knuckle Myb_DNA-binding PF00249.31 RJW61018.1 - 2.9e-29 101.0 0.0 2.3e-10 40.5 0.1 4.7 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RJW61018.1 - 3.1e-20 72.2 0.0 7.6e-11 42.1 0.0 5.0 2 1 3 5 5 5 4 Myb-like DNA-binding domain AAA_6 PF12774.7 RJW61019.1 - 1e-151 504.5 0.0 1.4e-150 500.8 0.0 3.0 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 RJW61019.1 - 4.5e-147 491.1 6.5 4.5e-147 491.1 6.5 4.0 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RJW61019.1 - 6.4e-117 391.0 30.5 1e-109 367.3 13.4 4.6 4 1 0 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 RJW61019.1 - 5.8e-73 244.2 0.4 1.9e-69 232.8 0.0 3.8 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_8 PF12780.7 RJW61019.1 - 4.3e-56 190.1 1.4 2e-54 184.7 0.1 4.0 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 Dynein_AAA_lid PF17852.1 RJW61019.1 - 4.5e-31 107.6 0.3 2.3e-30 105.3 0.3 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RJW61019.1 - 3.5e-27 95.1 0.0 1.6e-12 47.6 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RJW61019.1 - 1.5e-21 76.4 1.4 4.6e-21 74.9 0.2 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 RJW61019.1 - 2.2e-10 41.1 0.0 0.0015 18.9 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RJW61019.1 - 7.3e-08 32.8 0.2 0.044 14.0 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 RJW61019.1 - 3.1e-07 31.0 0.0 1.4 9.5 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 RJW61019.1 - 1.1e-05 25.9 0.9 0.12 12.7 0.0 5.2 6 0 0 6 6 5 1 AAA ATPase domain Mg_chelatase PF01078.21 RJW61019.1 - 0.00056 19.4 0.0 0.064 12.6 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 RJW61019.1 - 0.0064 16.2 1.1 17 5.1 0.1 4.1 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 RJW61019.1 - 0.0084 15.2 0.2 4.4 6.3 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_33 PF13671.6 RJW61019.1 - 0.015 15.4 0.0 16 5.6 0.0 3.8 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 RJW61019.1 - 0.024 14.6 2.1 1.5 8.9 0.0 3.7 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 3H PF02829.14 RJW61019.1 - 0.025 14.8 0.1 0.7 10.2 0.1 3.0 2 0 0 2 2 2 0 3H domain ABC_tran PF00005.27 RJW61019.1 - 0.028 14.9 0.3 13 6.2 0.0 3.7 3 0 0 3 3 3 0 ABC transporter IstB_IS21 PF01695.17 RJW61019.1 - 0.044 13.5 0.1 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 RJW61019.1 - 0.092 12.5 1.9 23 4.8 0.1 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 RJW61019.1 - 0.14 11.8 0.0 3.6 7.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_19 PF13245.6 RJW61019.1 - 0.16 12.3 0.8 7.1 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 RJW61019.1 - 0.2 11.7 1.9 1.5 8.9 0.0 3.5 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_11 PF13086.6 RJW61019.1 - 0.3 10.8 3.5 1.6 8.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain Ion_trans PF00520.31 RJW61020.1 - 1.1e-19 70.7 7.5 2.3e-19 69.6 7.5 1.5 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 RJW61020.1 - 4.3e-11 43.2 0.1 0.0026 18.3 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW61020.1 - 3.2e-08 33.7 1.8 0.00021 21.5 0.2 4.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW61020.1 - 5.9e-07 29.9 0.0 0.13 12.9 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW61020.1 - 9.1e-07 28.7 1.3 0.89 10.3 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RJW61020.1 - 3e-05 24.3 1.0 0.006 17.0 0.3 3.3 3 0 0 3 3 3 1 Ankyrin repeat Glyco_hydro_61 PF03443.14 RJW61020.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 CoA_binding_3 PF13727.6 RJW61020.1 - 0.59 10.1 3.4 9.4 6.2 0.2 2.5 2 0 0 2 2 2 0 CoA-binding domain CH PF00307.31 RJW61021.1 - 2.1e-28 98.7 0.0 1.9e-12 47.3 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW61021.1 - 0.0015 18.4 0.2 0.0054 16.5 0.1 2.0 2 0 0 2 2 2 1 CAMSAP CH domain DDHD PF02862.17 RJW61022.1 - 1.1e-48 166.3 0.6 8.1e-48 163.5 0.1 2.2 2 0 0 2 2 2 1 DDHD domain WWE PF02825.20 RJW61022.1 - 0.00019 22.0 0.5 0.057 14.0 0.2 2.6 1 1 1 2 2 2 2 WWE domain MBOAT PF03062.19 RJW61024.1 - 1.5e-35 123.2 0.3 2.2e-35 122.6 0.2 1.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family BCMA-Tall_bind PF09257.10 RJW61025.1 - 1.9 8.6 6.4 45 4.3 4.0 2.4 2 0 0 2 2 2 0 BCMA, TALL-1 binding zf-RING_UBOX PF13445.6 RJW61026.1 - 2.2e-07 30.8 5.8 2.2e-07 30.7 2.0 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.24 RJW61026.1 - 2.4e-07 30.8 7.0 2.1e-05 24.6 1.7 5.2 5 1 0 5 5 4 2 B-box zinc finger zf-RING_5 PF14634.6 RJW61026.1 - 2.5e-05 24.1 4.8 2.5e-05 24.1 4.8 5.0 5 0 0 5 5 5 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RJW61026.1 - 0.00023 21.0 5.2 0.00023 21.0 5.2 4.4 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RJW61026.1 - 0.00085 19.4 3.8 0.00085 19.4 3.8 4.8 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RJW61026.1 - 0.0055 16.5 5.9 0.0055 16.5 5.9 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) APG17 PF04108.12 RJW61026.1 - 0.0076 15.4 0.2 0.012 14.7 0.2 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 zf-RING_2 PF13639.6 RJW61026.1 - 0.019 15.3 4.0 0.019 15.3 4.0 4.8 5 1 0 5 5 4 0 Ring finger domain Golgin_A5 PF09787.9 RJW61026.1 - 0.23 10.9 4.5 0.084 12.3 1.4 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 IBR PF01485.21 RJW61026.1 - 0.83 9.9 19.5 0.73 10.1 0.3 4.5 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain HAUS6_N PF14661.6 RJW61026.1 - 0.86 9.1 4.9 0.42 10.2 1.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Cys_rich_CPCC PF14206.6 RJW61026.1 - 1.6 8.6 7.4 0.26 11.1 0.2 3.1 4 0 0 4 4 4 0 Cysteine-rich CPCC zf-Sec23_Sec24 PF04810.15 RJW61026.1 - 4.1 7.5 9.7 1.8 8.7 1.2 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger ETX_MTX2 PF03318.13 RJW61029.1 - 0.00084 19.2 1.4 0.0055 16.5 1.4 2.0 1 1 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 RIB43A PF05914.12 RJW61031.1 - 2e-129 431.6 56.3 2.3e-129 431.4 56.3 1.0 1 0 0 1 1 1 1 RIB43A Dna2 PF08696.11 RJW61032.1 - 0.025 14.4 0.2 0.045 13.6 0.0 1.4 2 0 0 2 2 2 0 DNA replication factor Dna2 RT_RNaseH_2 PF17919.1 RJW61033.1 - 5.6e-10 39.2 0.1 1e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW61033.1 - 2e-08 34.4 0.0 3.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Neur_chan_LBD PF02931.23 RJW61035.1 - 5.4e-54 182.9 3.1 8.9e-54 182.2 3.1 1.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW61035.1 - 0.0003 20.9 2.4 0.00048 20.3 2.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Prominin PF05478.11 RJW61036.1 - 1.6e-06 26.4 8.5 0.031 12.3 0.2 4.5 3 2 0 3 3 3 3 Prominin DUF2627 PF11118.8 RJW61036.1 - 0.01 16.4 2.9 0.23 12.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2627) LrgB PF04172.16 RJW61036.1 - 0.038 13.5 1.1 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 LrgB-like family Glucos_trans_II PF14264.6 RJW61036.1 - 0.083 12.2 0.1 0.083 12.2 0.1 2.7 3 0 0 3 3 3 0 Glucosyl transferase GtrII Adeno_E3_CR2 PF02439.15 RJW61036.1 - 0.17 11.6 0.2 0.63 9.8 0.2 2.0 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Spectrin PF00435.21 RJW61037.1 - 1.6e-241 783.9 154.3 5.9e-21 74.9 8.2 17.4 17 0 0 17 17 17 17 Spectrin repeat CH PF00307.31 RJW61037.1 - 2.2e-46 156.5 2.7 5.3e-24 84.5 0.0 3.8 4 0 0 4 4 4 2 Calponin homology (CH) domain PH_9 PF15410.6 RJW61037.1 - 3.6e-19 69.3 0.1 1.8e-18 67.0 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 RJW61037.1 - 3.4e-13 50.0 0.0 9.5e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 PH domain CAMSAP_CH PF11971.8 RJW61037.1 - 2.9e-07 30.2 0.1 9.9e-05 22.1 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain CHASE9 PF17153.4 RJW61037.1 - 0.13 12.4 1.5 1.2 9.3 0.1 2.8 2 0 0 2 2 2 0 Periplasmic sensor domain, extracellular DUF883 PF05957.13 RJW61038.1 - 0.00075 20.1 2.7 0.00075 20.1 2.7 6.3 3 3 3 6 6 6 1 Bacterial protein of unknown function (DUF883) DUF357 PF04010.13 RJW61038.1 - 0.28 11.3 2.3 0.67 10.1 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF5481 PF17578.2 RJW61038.1 - 0.32 11.4 2.0 1.1 9.7 0.0 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5481) Vac_Fusion PF02346.16 RJW61038.1 - 1.6 8.4 12.9 3.3 7.4 1.2 4.0 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF4735 PF15882.5 RJW61039.1 - 7.9e-56 189.6 0.0 9.5e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) LSM PF01423.22 RJW61041.1 - 2.9e-14 52.5 0.0 5e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RJW61041.1 - 0.049 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain SRI PF08236.11 RJW61042.1 - 0.14 12.4 3.5 0.47 10.7 3.5 1.8 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Pkinase PF00069.25 RJW61044.1 - 3.9e-09 36.3 0.2 1.8e-08 34.1 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61044.1 - 0.012 14.9 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase MOEP19 PF16005.5 RJW61044.1 - 0.13 12.3 0.0 10 6.2 0.1 2.8 3 0 0 3 3 3 0 KH-like RNA-binding domain Nmad2 PF18753.1 RJW61044.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 ABC_tran PF00005.27 RJW61046.1 - 1.8e-34 119.2 0.0 2.9e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RJW61046.1 - 2.6e-08 33.6 0.3 4.5e-05 23.0 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RJW61046.1 - 2.3e-06 28.1 1.2 4.7e-06 27.1 1.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 RJW61046.1 - 0.00017 21.3 1.3 0.0034 17.1 0.9 2.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW61046.1 - 0.00022 21.5 1.0 0.0037 17.5 0.9 2.6 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 RJW61046.1 - 0.00032 19.6 0.1 0.0035 16.2 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 RJW61046.1 - 0.00059 19.5 0.1 0.0023 17.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RJW61046.1 - 0.0028 17.6 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 RJW61046.1 - 0.0042 16.7 4.5 0.076 12.6 0.5 3.4 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 RJW61046.1 - 0.0058 16.8 0.5 0.1 12.8 0.5 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 RJW61046.1 - 0.0081 15.3 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA PF00004.29 RJW61046.1 - 0.0091 16.4 0.0 0.1 13.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.6 RJW61046.1 - 0.0093 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) AAA_5 PF07728.14 RJW61046.1 - 0.012 15.6 0.1 0.1 12.6 0.0 2.3 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 RJW61046.1 - 0.013 15.3 0.1 1.2 8.9 0.0 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 RJW61046.1 - 0.017 14.4 0.1 0.037 13.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.20 RJW61046.1 - 0.022 14.6 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase DEAD PF00270.29 RJW61046.1 - 0.023 14.5 0.0 0.062 13.1 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF815 PF05673.13 RJW61046.1 - 0.026 13.7 0.1 0.44 9.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 RJW61046.1 - 0.032 14.0 0.0 0.09 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 RJW61046.1 - 0.035 14.0 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 RJW61046.1 - 0.041 14.4 0.0 0.1 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 RJW61046.1 - 0.042 13.6 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 RJW61046.1 - 0.042 13.3 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_PrkA PF08298.11 RJW61046.1 - 0.054 12.4 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_33 PF13671.6 RJW61046.1 - 0.072 13.3 2.3 0.072 13.2 0.8 2.1 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RJW61046.1 - 0.076 12.7 0.2 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 RJW61046.1 - 0.092 11.9 0.0 2.2 7.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Glyco_hydro_47 PF01532.20 RJW61047.1 - 2.3e-119 399.3 0.3 1.2e-63 215.6 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 APG12 PF04110.13 RJW61048.1 - 1.7e-33 114.9 0.0 1.9e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 RJW61048.1 - 2.9e-06 27.4 0.0 3.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Asparaginase_2 PF01112.18 RJW61050.1 - 1.2e-135 451.5 3.2 8.2e-72 241.8 0.2 3.1 4 0 0 4 4 4 2 Asparaginase DEAD PF00270.29 RJW61050.1 - 1.5e-50 171.4 0.0 3.2e-50 170.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW61050.1 - 1.9e-29 102.2 0.0 3.6e-28 98.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 RJW61050.1 - 0.088 12.1 0.0 0.088 12.1 0.0 3.0 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Zip PF02535.22 RJW61050.1 - 5.9 6.0 7.0 10 5.2 7.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SH2 PF00017.24 RJW61051.1 - 9.6e-17 60.9 0.0 2e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain FbpA PF05833.11 RJW61054.1 - 4.2e-33 114.8 10.0 1.4e-22 80.1 0.0 2.2 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 RJW61054.1 - 1.3e-29 102.2 1.2 3.4e-29 100.9 0.0 2.4 2 0 0 2 2 2 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 RJW61054.1 - 9.6e-29 100.2 0.0 3e-28 98.6 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF5590 PF17881.1 RJW61054.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) 4HBT PF03061.22 RJW61055.1 - 7.8e-08 32.6 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 RJW61055.1 - 0.0049 17.1 0.0 0.0085 16.4 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily CSD PF00313.22 RJW61056.1 - 4.3e-15 55.3 0.0 5.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 RJW61056.1 - 0.035 14.2 10.8 0.47 10.6 0.9 2.6 2 0 0 2 2 2 0 Zinc knuckle OB_RNB PF08206.11 RJW61056.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain zf-CCHC_4 PF14392.6 RJW61056.1 - 0.49 10.2 7.7 4.3 7.1 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle CN_hydrolase PF00795.22 RJW61057.1 - 3.2e-56 190.6 0.0 1.3e-54 185.3 0.0 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase HIT PF01230.23 RJW61057.1 - 1.1e-20 74.2 0.0 3e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 HIT domain tRNA_synt_1c_R2 PF04557.15 RJW61058.1 - 0.036 15.0 0.1 36 5.4 0.0 3.5 3 0 0 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Myb_DNA-bind_5 PF13873.6 RJW61061.1 - 8.8e-14 51.4 2.2 1.9e-13 50.3 2.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RJW61061.1 - 2.3e-06 27.9 0.2 4.2e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RJW61061.1 - 0.0088 16.3 2.5 0.012 15.9 0.5 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 RJW61061.1 - 0.039 14.2 0.3 0.12 12.7 0.3 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain EF-hand_1 PF00036.32 RJW61062.1 - 5.5e-28 94.4 7.7 0.00011 21.5 0.0 6.6 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 RJW61062.1 - 2.5e-25 88.7 8.6 1.6e-08 34.8 0.2 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW61062.1 - 5.5e-24 82.6 9.7 0.0002 20.7 0.0 6.8 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 RJW61062.1 - 3.4e-21 73.3 13.9 0.00033 20.4 0.0 6.7 6 0 0 6 6 6 6 EF-hand domain EF-hand_8 PF13833.6 RJW61062.1 - 1.4e-16 60.1 4.1 0.013 15.3 0.0 6.3 6 0 0 6 6 6 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW61062.1 - 8.5e-09 35.7 9.3 0.017 15.4 0.1 4.0 2 2 2 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 RJW61062.1 - 1.6e-06 27.9 4.8 1.4 8.9 0.0 5.2 5 1 0 5 5 5 3 EF hand Pox_F12L PF03337.13 RJW61062.1 - 0.009 14.2 0.0 0.012 13.8 0.0 1.1 1 0 0 1 1 1 1 Poxvirus F12L protein Dockerin_1 PF00404.18 RJW61062.1 - 0.026 14.7 9.5 12 6.2 1.3 5.2 4 2 1 5 5 5 0 Dockerin type I domain DUF1707 PF08044.11 RJW61062.1 - 0.14 12.3 0.2 27 4.9 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) LRR_4 PF12799.7 RJW61064.1 - 4.2e-08 33.4 3.2 0.0003 21.1 0.4 3.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW61064.1 - 1.9e-06 27.5 0.5 8.3e-05 22.2 0.5 2.3 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RJW61064.1 - 2.5e-06 27.2 1.9 0.0094 15.7 0.5 3.6 3 1 1 4 4 4 2 Leucine rich repeat Exog_C PF18026.1 RJW61064.1 - 0.04 14.0 0.2 7.1 6.8 0.1 2.6 1 1 1 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain LRR_1 PF00560.33 RJW61064.1 - 0.15 12.7 0.7 1.2e+02 3.9 0.1 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat GDI PF00996.18 RJW61065.1 - 4.5e-203 674.6 0.8 5.2e-203 674.4 0.8 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 RJW61065.1 - 0.00047 19.6 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NHL PF01436.21 RJW61066.1 - 0.00035 20.4 0.1 0.00061 19.7 0.1 1.4 1 0 0 1 1 1 1 NHL repeat WD40 PF00400.32 RJW61067.1 - 2.5e-14 53.4 7.5 1e-07 32.5 0.2 6.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW61067.1 - 8.6e-09 35.6 0.9 0.09 13.1 0.0 4.7 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_7 PF13176.6 RJW61067.1 - 6.5e-05 22.7 7.3 0.34 11.0 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat eIF2A PF08662.11 RJW61067.1 - 0.00011 22.1 0.0 0.00043 20.2 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 RJW61067.1 - 0.00018 20.7 2.3 0.12 11.4 0.0 4.0 4 2 1 5 5 5 2 Coatomer WD associated region WD40_like PF17005.5 RJW61067.1 - 0.0026 17.1 0.0 0.75 9.1 0.0 3.1 2 1 1 3 3 3 1 WD40-like domain ANAPC3 PF12895.7 RJW61067.1 - 0.0035 17.5 1.4 5.4 7.3 0.1 4.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PHTB1_N PF14727.6 RJW61067.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 PTHB1 N-terminus TPR_19 PF14559.6 RJW61067.1 - 0.37 11.3 7.8 4 8.0 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 RJW61067.1 - 0.41 10.5 9.7 3.7 7.5 1.0 3.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 RJW61067.1 - 0.45 10.8 0.0 0.45 10.8 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 RJW61067.1 - 5.6 8.1 14.4 13 6.9 0.1 6.0 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF4704 PF15787.5 RJW61068.1 - 2.8e-90 302.3 0.5 6e-90 301.3 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 RJW61068.1 - 7.5e-12 45.6 0.0 1.3e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Metallophos PF00149.28 RJW61069.1 - 1.4e-18 68.1 0.7 2.1e-18 67.6 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RJW61069.1 - 0.082 13.4 1.2 0.2 12.1 1.2 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain S1 PF00575.23 RJW61070.1 - 0.0017 18.6 0.2 0.002 18.4 0.2 1.1 1 0 0 1 1 1 1 S1 RNA binding domain DHHC PF01529.20 RJW61071.1 - 3.6e-33 114.5 10.1 3.6e-33 114.5 10.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Sugar_tr PF00083.24 RJW61072.1 - 1e-105 354.2 16.6 1.2e-105 354.0 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW61072.1 - 4.2e-19 68.7 24.2 4.2e-19 68.7 24.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily GDI PF00996.18 RJW61073.1 - 2.8e-130 434.7 0.0 3.2e-130 434.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 RJW61073.1 - 2.6e-05 23.7 0.0 3.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Metallophos PF00149.28 RJW61074.1 - 4.1e-18 66.6 0.0 6e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SapB_1 PF05184.15 RJW61075.1 - 3.2e-08 33.4 10.1 0.033 14.2 0.0 4.9 5 0 0 5 5 5 3 Saposin-like type B, region 1 DNA_pol_phi PF04931.13 RJW61075.1 - 0.097 10.8 0.1 0.45 8.6 0.1 1.9 1 1 1 2 2 2 0 DNA polymerase phi Sugar_tr PF00083.24 RJW61076.1 - 2.6e-106 356.2 15.1 2.9e-106 356.0 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW61076.1 - 8.4e-20 71.0 16.1 8.4e-20 71.0 16.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM141 PF15110.6 RJW61076.1 - 0.058 14.0 1.4 0.78 10.4 0.0 3.0 3 0 0 3 3 3 0 TMEM141 protein family ODR4-like PF14778.6 RJW61077.1 - 4.1e-42 144.5 0.0 1.9e-41 142.3 0.0 1.8 1 1 0 1 1 1 1 Olfactory receptor 4-like cNMP_binding PF00027.29 RJW61079.1 - 1.3e-13 50.8 0.0 2.2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain BAR PF03114.18 RJW61079.1 - 0.012 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 BAR domain Baculo_PEP_C PF04513.12 RJW61079.1 - 0.041 13.9 1.4 0.089 12.8 1.0 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4349 PF14257.6 RJW61079.1 - 0.06 12.8 0.2 0.25 10.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Cep57_CLD PF14073.6 RJW61079.1 - 0.097 12.7 0.8 0.19 11.7 0.8 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 RP-C_C PF11800.8 RJW61079.1 - 0.12 12.5 1.0 0.27 11.3 1.0 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region FlgT_M PF16539.5 RJW61079.1 - 0.12 12.5 0.5 0.4 10.8 0.7 1.7 2 0 0 2 2 2 0 Flagellar assembly protein T, middle domain MscS_porin PF12795.7 RJW61079.1 - 0.28 10.7 2.8 0.5 9.9 2.8 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain VP4_helical PF17478.2 RJW61079.1 - 0.53 9.7 2.0 0.38 10.1 0.2 1.6 2 0 0 2 2 2 0 Rotavirus VP4 helical domain ThiD2 PF17792.1 RJW61081.1 - 0.26 11.7 3.4 0.19 12.2 1.1 1.9 2 0 0 2 2 2 0 ThiD2 family DDE_Tnp_IS66 PF03050.14 RJW61081.1 - 0.63 9.5 3.7 0.9 9.0 0.5 2.1 2 0 0 2 2 2 0 Transposase IS66 family DUF737 PF05300.11 RJW61081.1 - 6.9 7.0 10.5 0.64 10.3 5.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DDT PF02791.17 RJW61082.1 - 4.1e-14 52.6 0.1 8.2e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 DDT domain PHD PF00628.29 RJW61082.1 - 2.2e-08 33.9 11.3 5.9e-08 32.5 11.3 1.8 1 0 0 1 1 1 1 PHD-finger VWA_N2 PF16164.5 RJW61082.1 - 0.11 12.6 5.0 2.3 8.4 3.5 3.1 2 0 0 2 2 2 0 VWA N-terminal KELK PF15796.5 RJW61082.1 - 0.18 12.3 7.0 0.26 11.8 1.2 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Prominin PF05478.11 RJW61082.1 - 0.41 8.5 0.5 3.2 5.6 0.0 2.0 2 0 0 2 2 2 0 Prominin zf-PHD-like PF15446.6 RJW61082.1 - 0.67 9.6 4.4 2 8.0 4.4 1.8 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Spc24 PF08286.11 RJW61082.1 - 1.1 9.5 7.8 14 5.9 1.9 3.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 zf-CpG_bind_C PF12269.8 RJW61082.1 - 1.5 8.5 6.4 2.6 7.8 1.5 2.6 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain GAS PF13851.6 RJW61082.1 - 3 7.1 8.4 1.8 7.9 2.7 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 RJW61082.1 - 4.5 7.8 21.6 0.23 12.0 0.2 4.2 4 0 0 4 4 4 0 Apg6 coiled-coil region Prok-RING_1 PF14446.6 RJW61082.1 - 8.1 6.5 10.5 23 5.0 10.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF3544 PF12064.8 RJW61084.1 - 0.058 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein kinase C-binding protein 1 fn3 PF00041.21 RJW61085.1 - 5.8e-23 81.1 33.3 6e-06 26.5 0.3 8.1 8 0 0 8 8 8 5 Fibronectin type III domain Interfer-bind PF09294.10 RJW61085.1 - 8.4e-05 22.8 17.0 0.51 10.7 0.2 6.0 6 0 0 6 6 6 3 Interferon-alpha/beta receptor, fibronectin type III DUF3331 PF11811.8 RJW61085.1 - 0.0015 18.4 9.0 11 6.0 0.0 6.1 6 0 0 6 6 6 2 Domain of unknown function (DUF3331) COE1_DBD PF16422.5 RJW61085.1 - 0.011 15.2 0.6 42 3.5 0.0 4.2 5 0 0 5 5 5 0 Transcription factor COE1 DNA-binding domain FlgD_ig PF13860.6 RJW61085.1 - 0.012 15.4 4.6 68 3.4 0.0 5.4 5 0 0 5 5 5 0 FlgD Ig-like domain XPB_DRD PF18458.1 RJW61085.1 - 0.023 14.6 1.6 0.13 12.2 0.2 3.0 4 0 0 4 4 4 0 Xeroderma pigmentosum group B helicase damage recognition domain NPCBM_assoc PF10633.9 RJW61085.1 - 0.26 11.6 2.4 31 4.9 0.1 3.5 3 1 1 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF2839 PF10999.8 RJW61085.1 - 7.1 7.1 6.7 1.4e+02 2.9 0.7 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2839) Glyco_transf_8 PF01501.20 RJW61086.1 - 1.2e-07 31.6 1.7 5.4e-05 22.9 0.1 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 8 Pkinase PF00069.25 RJW61088.1 - 1.8e-18 66.9 0.0 2.8e-18 66.3 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61088.1 - 5.2e-15 55.4 0.1 1.7e-11 43.9 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase QVR PF17064.5 RJW61090.1 - 0.00011 22.3 5.5 0.00022 21.4 5.5 1.5 1 1 0 1 1 1 1 Sleepless protein PKD_3 PF16820.5 RJW61091.1 - 0.0018 18.0 1.2 12 5.8 0.0 3.7 3 0 0 3 3 3 2 PKD-like domain DUF99 PF01949.16 RJW61091.1 - 0.0022 17.4 0.0 4.1 6.8 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function DUF99 ATPgrasp_N PF18130.1 RJW61091.1 - 0.0075 16.8 1.1 23 5.6 0.0 3.6 3 0 0 3 3 3 1 ATP-grasp N-terminal domain THDPS_M PF14789.6 RJW61091.1 - 0.071 13.2 4.9 56 3.9 0.1 4.4 4 0 0 4 4 4 0 Tetrahydrodipicolinate N-succinyltransferase middle DUF5518 PF17647.1 RJW61091.1 - 0.22 11.7 1.8 31 4.7 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5518) zf-C2H2_4 PF13894.6 RJW61092.1 - 1.9e-20 71.8 138.1 0.0063 17.3 0.8 18.6 18 0 0 18 18 18 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW61092.1 - 1.6e-14 53.6 80.2 0.00034 20.9 2.4 14.0 14 0 0 14 14 14 8 Zinc-finger double domain zf-C2H2 PF00096.26 RJW61092.1 - 7.3e-09 35.6 139.0 0.00068 20.0 3.9 15.2 18 0 0 18 18 18 8 Zinc finger, C2H2 type zf-Di19 PF05605.12 RJW61092.1 - 1.7e-05 25.0 10.9 9.4e-05 22.6 1.0 9.4 7 2 3 11 11 11 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 RJW61092.1 - 0.023 14.4 0.4 0.023 14.4 0.4 7.9 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 RJW61092.1 - 0.024 15.3 51.7 0.038 14.7 0.1 9.4 3 2 6 9 9 9 0 Zinc finger C2H2-type, 3 repeats TFB6 PF17110.5 RJW61092.1 - 1.5 8.5 5.7 3.1 7.5 5.7 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH zf-CHCC PF10276.9 RJW61092.1 - 5.7 7.1 20.4 1 9.5 0.7 5.3 6 0 0 6 6 6 0 Zinc-finger domain Asp PF00026.23 RJW61094.1 - 3.2e-25 89.2 0.0 3.4e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease RVT_1 PF00078.27 RJW61095.1 - 1.3e-52 178.6 0.0 1.5e-46 158.7 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Tn7_Tnp_TnsA_C PF08721.11 RJW61096.1 - 0.084 13.5 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 TnsA endonuclease C terminal RVT_1 PF00078.27 RJW61097.1 - 5e-05 22.9 0.1 0.15 11.6 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) CUB PF00431.20 RJW61099.1 - 3.1e-71 236.7 0.0 1.5e-19 70.4 0.0 4.2 4 0 0 4 4 4 4 CUB domain DHC_N1 PF08385.12 RJW61100.1 - 1.8e-106 357.0 0.1 3.6e-106 356.0 0.1 1.5 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 MIF4G PF02854.19 RJW61101.1 - 9.8e-20 71.1 0.3 1.8e-19 70.3 0.3 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 RJW61101.1 - 2.5e-14 53.2 1.3 3.9e-10 39.7 0.0 3.1 3 0 0 3 3 3 2 MA3 domain Cnd1 PF12717.7 RJW61101.1 - 0.1 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Histone PF00125.24 RJW61102.1 - 6.5e-36 123.6 0.1 9.1e-36 123.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RJW61102.1 - 0.0043 17.1 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold RNase_H2-Ydr279 PF09468.10 RJW61104.1 - 7.3e-08 32.8 0.1 1.3e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 RJW61106.1 - 6.6e-11 42.3 0.0 8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain adh_short PF00106.25 RJW61107.1 - 1.6e-25 89.7 1.1 2.9e-13 49.7 0.4 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RJW61107.1 - 7e-19 68.3 2.3 3.2e-10 40.0 1.0 3.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW61107.1 - 1.3e-05 25.2 0.1 6.8e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 KR domain ADP_PFK_GK PF04587.15 RJW61108.1 - 1.8e-99 333.2 0.0 3.3e-57 194.0 0.0 3.9 3 1 0 3 3 3 3 ADP-specific Phosphofructokinase/Glucokinase conserved region PfkB PF00294.24 RJW61108.1 - 0.13 11.5 0.0 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 pfkB family carbohydrate kinase CDI PF02234.19 RJW61109.1 - 0.0099 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Fil_haemagg_2 PF13332.6 RJW61109.1 - 0.69 10.0 6.7 1.4 9.0 6.7 1.4 1 0 0 1 1 1 0 Hemagglutinin repeat Tetraspanin PF00335.20 RJW61112.1 - 1e-12 48.3 0.7 1e-12 48.3 0.7 2.2 2 0 0 2 2 2 1 Tetraspanin family RVT_1 PF00078.27 RJW61114.1 - 1.2e-10 41.3 0.1 1.3e-09 37.9 0.0 2.1 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Diphthamide_syn PF01866.17 RJW61116.1 - 2.4e-113 378.6 0.0 3.5e-113 378.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein UPF0506 PF11703.8 RJW61117.1 - 3.3e-20 72.2 23.5 4.1e-20 71.9 23.5 1.1 1 0 0 1 1 1 1 UPF0506 Toxin_21 PF08091.11 RJW61117.1 - 0.0047 16.8 7.9 0.0047 16.8 7.9 2.6 2 1 0 2 2 2 1 Spider insecticidal peptide Dickkopf_N PF04706.12 RJW61117.1 - 0.46 11.0 22.0 5.5 7.6 22.1 2.2 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Conotoxin_I2 PF17557.2 RJW61117.1 - 3.3 7.9 21.3 0.59 10.3 9.7 2.4 2 1 0 2 2 2 0 I2-superfamily conotoxins PDZ PF00595.24 RJW61118.1 - 8e-15 55.0 5.5 2.9e-09 37.1 0.2 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RJW61118.1 - 5.7e-14 51.7 0.1 1.3e-05 24.9 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RJW61118.1 - 2e-08 34.5 0.5 4.4e-05 23.7 0.1 2.3 2 0 0 2 2 2 2 PDZ domain FYVE PF01363.21 RJW61120.1 - 4e-14 52.5 16.8 1.3e-13 50.9 16.8 1.9 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_UBOX PF13445.6 RJW61120.1 - 0.059 13.4 7.6 0.18 11.9 7.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 RJW61120.1 - 0.4 11.1 14.4 1.4 9.3 14.4 2.1 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 RJW61120.1 - 0.7 9.9 16.1 2.4 8.2 16.1 2.0 1 0 0 1 1 1 0 zinc-RING finger domain UPF0506 PF11703.8 RJW61121.1 - 5.7e-21 74.7 21.9 6.7e-21 74.4 21.9 1.1 1 0 0 1 1 1 1 UPF0506 Omega-toxin PF06357.11 RJW61121.1 - 0.014 15.2 5.1 0.014 15.2 5.1 1.9 2 0 0 2 2 2 0 Omega-atracotoxin Conotoxin_I2 PF17557.2 RJW61121.1 - 0.016 15.3 9.3 0.016 15.3 9.3 2.3 2 0 0 2 2 2 0 I2-superfamily conotoxins Dickkopf_N PF04706.12 RJW61121.1 - 0.12 12.9 21.7 0.16 12.5 18.9 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Conotoxin PF02950.17 RJW61121.1 - 8.3 7.5 24.1 2.2 9.3 10.6 2.3 1 1 1 2 2 2 0 Conotoxin RRM_1 PF00076.22 RJW61122.1 - 8.8e-15 54.3 0.0 1.6e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MARVEL PF01284.23 RJW61123.1 - 2.9e-08 33.8 27.1 1.1e-07 31.9 27.1 1.8 1 1 0 1 1 1 1 Membrane-associating domain YfhO PF09586.10 RJW61123.1 - 2.5 6.2 9.0 3.2 5.9 9.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DNApol_Exo PF18136.1 RJW61124.1 - 0.11 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Zincin_2 PF10103.9 RJW61124.1 - 0.12 11.6 0.0 0.51 9.5 0.0 1.9 2 0 0 2 2 2 0 Zincin-like metallopeptidase DUF2225 PF09986.9 RJW61127.1 - 0.028 14.2 0.2 0.053 13.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) HTH_AraC PF00165.23 RJW61127.1 - 0.21 11.8 2.9 4.2 7.6 0.4 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Replicase PF03090.17 RJW61128.1 - 0.04 13.8 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Replicase family Joubert PF15392.6 RJW61130.1 - 0.0045 16.8 0.2 0.006 16.4 0.2 1.1 1 0 0 1 1 1 1 Joubert syndrome-associated Phage_lysozyme PF00959.19 RJW61130.1 - 0.056 13.9 0.0 0.063 13.7 0.0 1.1 1 0 0 1 1 1 0 Phage lysozyme Lactamase_B PF00753.27 RJW61132.1 - 0.00019 21.5 0.1 0.00027 21.0 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RJW61132.1 - 0.0035 16.9 0.1 0.0044 16.6 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SKA1 PF07160.12 RJW61134.1 - 0.022 14.6 8.8 0.046 13.6 8.8 1.5 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 cNMP_binding PF00027.29 RJW61134.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain 7TM_GPCR_Srx PF10328.9 RJW61135.1 - 0.0083 15.8 24.4 0.016 14.9 24.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RJW61135.1 - 0.024 14.0 22.5 0.035 13.4 22.5 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) cNMP_binding PF00027.29 RJW61136.1 - 8.6e-06 25.7 0.4 0.015 15.4 0.0 3.2 2 1 1 3 3 3 2 Cyclic nucleotide-binding domain E1_DerP2_DerF2 PF02221.15 RJW61137.1 - 9.5e-09 35.8 0.0 1.1e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 ML domain ubiquitin PF00240.23 RJW61139.1 - 2e-08 33.9 0.0 3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 RJW61139.1 - 0.0032 17.6 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 RJW61139.1 - 0.0047 17.5 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PAN_1 PF00024.26 RJW61140.1 - 0.0038 17.2 0.1 0.0088 16.0 0.1 1.6 1 0 0 1 1 1 1 PAN domain EF-hand_1 PF00036.32 RJW61144.1 - 2.5e-15 54.8 0.2 1.2e-07 30.8 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 RJW61144.1 - 2.7e-14 51.9 0.7 7e-08 31.6 0.2 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW61144.1 - 7.6e-13 47.3 0.2 2.8e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RJW61144.1 - 2.6e-12 47.0 0.0 2.9e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW61144.1 - 9.9e-10 38.1 0.2 0.00019 21.2 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 RJW61144.1 - 0.028 14.4 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EspA PF03433.13 RJW61144.1 - 0.033 14.0 0.4 0.075 12.9 0.4 1.5 1 1 0 1 1 1 0 EspA-like secreted protein DUF3349 PF11829.8 RJW61144.1 - 0.05 14.4 0.0 0.12 13.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) GHD PF17834.1 RJW61144.1 - 0.061 13.4 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase EF-hand_13 PF17958.1 RJW61144.1 - 0.095 12.5 0.0 0.44 10.4 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 RJW61144.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2043 PF09740.9 RJW61145.1 - 1.2e-11 45.2 1.1 7.6e-11 42.6 0.2 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) CENP-B_dimeris PF09026.10 RJW61146.1 - 0.0034 17.7 13.5 0.0042 17.4 13.5 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 RJW61146.1 - 0.026 12.7 5.8 0.026 12.6 5.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 RJW61146.1 - 0.041 14.1 4.7 0.056 13.7 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 RJW61146.1 - 0.076 12.3 11.0 0.098 12.0 11.0 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 RJW61146.1 - 0.11 12.4 1.3 0.098 12.5 1.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 RJW61146.1 - 0.15 12.1 2.0 0.14 12.2 2.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 RJW61146.1 - 0.17 11.5 0.5 0.17 11.6 0.5 1.1 1 0 0 1 1 1 0 FAM176 family Utp14 PF04615.13 RJW61146.1 - 0.34 9.4 2.1 0.31 9.6 2.1 1.0 1 0 0 1 1 1 0 Utp14 protein Cwf_Cwc_15 PF04889.12 RJW61146.1 - 0.66 9.7 12.7 0.83 9.3 12.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 RJW61146.1 - 0.75 9.3 3.7 0.73 9.4 3.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting SDA1 PF05285.12 RJW61146.1 - 0.75 9.2 4.1 0.83 9.0 4.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RJW61146.1 - 5.9 5.0 5.5 6.5 4.8 5.5 1.0 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 RJW61147.1 - 2.8e-41 141.5 0.0 7.7e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW61147.1 - 3.9e-07 29.9 0.0 9.3e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW61147.1 - 0.0028 17.2 0.1 0.0091 15.5 0.1 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family EF-hand_7 PF13499.6 RJW61150.1 - 1.2e-15 57.7 3.8 1.6e-09 38.1 0.6 1.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW61150.1 - 1.8e-11 43.0 0.2 2.6e-05 23.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RJW61150.1 - 9.4e-11 40.5 0.6 1.2e-07 30.8 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW61150.1 - 1.4e-10 40.9 1.9 1.8e-08 34.1 0.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW61150.1 - 1.4e-06 27.5 0.2 1.4e-06 27.5 0.2 3.2 3 1 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 RJW61150.1 - 0.00037 20.8 0.1 0.00064 20.0 0.1 1.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RJW61150.1 - 0.0094 16.3 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain HTH_32 PF13565.6 RJW61150.1 - 0.17 12.5 0.0 0.87 10.3 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain EF-hand_1 PF00036.32 RJW61151.1 - 2.7e-13 48.4 4.1 1.3e-08 33.7 0.7 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW61151.1 - 1.4e-12 46.4 4.6 3.5e-08 32.7 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RJW61151.1 - 3.1e-12 46.8 3.4 4.4e-12 46.3 3.4 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RJW61151.1 - 2.5e-10 39.4 5.4 9.7e-08 31.2 0.8 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW61151.1 - 4.9e-09 35.9 1.1 9e-05 22.2 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_13 PF17958.1 RJW61151.1 - 0.0066 16.2 0.0 0.071 12.9 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain DUF2666 PF10869.8 RJW61151.1 - 0.016 15.5 0.8 0.019 15.2 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) EF-hand_10 PF14788.6 RJW61151.1 - 0.022 14.6 0.7 0.022 14.6 0.7 1.8 2 1 0 2 2 2 0 EF hand DUF1834 PF08873.11 RJW61151.1 - 0.023 14.5 0.0 0.028 14.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) DUF5580 PF17743.1 RJW61151.1 - 0.023 13.2 0.1 0.023 13.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SPARC_Ca_bdg PF10591.9 RJW61151.1 - 0.024 14.9 0.2 0.033 14.5 0.2 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 RJW61151.1 - 0.028 14.4 1.6 1.5 8.8 0.6 2.1 1 1 1 2 2 2 0 Caleosin related protein DUF3231 PF11553.8 RJW61151.1 - 0.073 12.7 0.1 0.086 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) DUF1456 PF07308.13 RJW61151.1 - 0.091 13.1 1.0 0.17 12.2 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) EF-hand_1 PF00036.32 RJW61152.1 - 5.7e-16 56.8 1.2 1.7e-07 30.3 0.7 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW61152.1 - 4e-14 51.2 0.6 4.8e-07 29.2 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RJW61152.1 - 7e-14 50.6 2.0 8.6e-07 28.2 0.6 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW61152.1 - 1.6e-13 50.9 0.4 1.9e-13 50.6 0.4 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW61152.1 - 2.2e-10 40.2 0.5 1.4e-05 24.8 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EspA PF03433.13 RJW61152.1 - 0.0015 18.4 2.2 0.0039 17.1 2.2 1.5 1 1 0 1 1 1 1 EspA-like secreted protein SPARC_Ca_bdg PF10591.9 RJW61152.1 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1456 PF07308.13 RJW61152.1 - 0.013 15.8 0.7 0.039 14.3 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) EF-hand_4 PF12763.7 RJW61152.1 - 0.022 14.7 0.1 0.025 14.5 0.1 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 RJW61152.1 - 0.027 14.4 0.1 0.62 10.0 0.1 2.0 1 1 1 2 2 2 0 Caleosin related protein EF-hand_13 PF17958.1 RJW61152.1 - 0.03 14.1 0.0 0.79 9.6 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain EF-hand_9 PF14658.6 RJW61152.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 RJW61153.1 - 4.1e-16 57.3 0.7 8.3e-08 31.3 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW61153.1 - 3e-15 54.8 0.4 7.7e-07 28.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RJW61153.1 - 3.2e-13 48.5 3.5 1.5e-06 27.4 0.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW61153.1 - 4e-13 49.6 0.5 6e-13 49.0 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW61153.1 - 1.7e-10 40.6 0.3 0.00026 20.7 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EspA PF03433.13 RJW61153.1 - 0.0034 17.3 0.3 0.018 14.9 0.6 1.9 2 1 1 3 3 3 1 EspA-like secreted protein Caleosin PF05042.13 RJW61153.1 - 0.013 15.5 0.2 0.44 10.5 0.1 2.1 1 1 1 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 RJW61153.1 - 0.023 15.0 0.2 0.033 14.5 0.2 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 RJW61153.1 - 0.029 14.2 0.7 0.14 12.1 0.5 2.1 2 0 0 2 2 2 0 EF hand DUF1456 PF07308.13 RJW61153.1 - 0.045 14.1 0.1 0.42 11.0 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1456) DUF5617 PF18493.1 RJW61153.1 - 0.074 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) EF-hand_13 PF17958.1 RJW61153.1 - 0.079 12.8 0.0 15 5.5 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain adh_short PF00106.25 RJW61155.1 - 6.7e-38 130.1 0.1 8.9e-38 129.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW61155.1 - 5.3e-21 75.2 0.0 6.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW61155.1 - 6.1e-07 29.5 0.1 1.3e-06 28.4 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RJW61155.1 - 0.023 14.1 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RJW61155.1 - 0.034 14.0 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF4888 PF16229.5 RJW61155.1 - 0.053 13.5 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4888) 7tm_1 PF00001.21 RJW61156.1 - 3.5e-51 174.0 22.7 3.5e-51 174.0 22.7 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW61156.1 - 2.6e-14 53.2 20.9 4.9e-14 52.3 20.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RJW61156.1 - 1.3e-10 41.4 19.5 1.3e-10 41.4 19.5 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SLATT_5 PF18160.1 RJW61156.1 - 0.073 12.4 0.4 0.073 12.4 0.4 3.3 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain family 5 zf-RING_9 PF13901.6 RJW61157.1 - 7e-26 91.5 13.5 6.1e-25 88.4 0.9 2.3 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon Prok-RING_2 PF14445.6 RJW61157.1 - 0.0024 18.0 0.4 0.0024 18.0 0.4 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 2 C1_1 PF00130.22 RJW61157.1 - 0.021 14.7 9.3 0.021 14.7 9.3 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cript PF10235.9 RJW61157.1 - 2 9.1 11.4 0.13 12.8 0.8 3.2 4 0 0 4 4 4 0 Microtubule-associated protein CRIPT Asp PF00026.23 RJW61160.1 - 7e-36 124.2 0.0 9.3e-35 120.5 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW61160.1 - 4.6e-06 27.0 0.0 0.0002 21.7 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RJW61160.1 - 0.011 16.4 0.0 8.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Aspartyl protease GATA PF00320.27 RJW61160.1 - 0.26 10.9 1.1 0.49 10.0 1.1 1.5 1 0 0 1 1 1 0 GATA zinc finger XK-related PF09815.9 RJW61161.1 - 5.3e-99 331.5 30.8 7.4e-99 331.0 30.8 1.2 1 0 0 1 1 1 1 XK-related protein Carboxyl_trans PF01039.22 RJW61162.1 - 4.5e-188 625.9 0.0 5.2e-188 625.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain RVT_1 PF00078.27 RJW61163.1 - 5.1e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GTP_EFTU PF00009.27 RJW61164.1 - 8.3e-44 149.5 0.0 1.1e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 RJW61164.1 - 8.6e-37 126.4 5.0 1.6e-36 125.5 5.0 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 RJW61164.1 - 1.2e-22 79.7 0.0 2.8e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 RJW61164.1 - 8.6e-22 77.2 0.0 1.8e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 RJW61164.1 - 5.5e-12 45.9 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 RJW61164.1 - 1.9e-07 31.1 0.0 5.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 RJW61164.1 - 0.00091 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 RJW61164.1 - 0.0016 18.6 0.0 0.017 15.3 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RJW61164.1 - 0.032 13.8 0.0 0.14 11.7 0.0 1.9 1 1 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 RJW61164.1 - 0.14 12.1 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Pkinase PF00069.25 RJW61165.1 - 6.5e-69 232.2 0.0 8.5e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.10 RJW61165.1 - 2.8e-48 163.3 0.0 5e-48 162.5 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 RJW61165.1 - 8.5e-28 97.3 0.0 1.1e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4440 PF14534.6 RJW61165.1 - 2.2e-09 37.7 0.0 3.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 RJW61165.1 - 3.9e-08 33.6 0.0 6.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Pkinase_fungal PF17667.1 RJW61165.1 - 0.0025 16.7 0.0 0.0048 15.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RJW61165.1 - 0.021 14.8 0.0 2.6 7.9 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family eIF2A PF08662.11 RJW61166.1 - 6.9e-30 104.4 0.7 6.5e-27 94.7 0.0 3.5 4 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 RJW61166.1 - 5.9e-09 36.1 0.3 2.1 8.7 0.0 6.3 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 RJW61166.1 - 8.2e-09 35.2 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RJW61166.1 - 0.006 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 RJW61166.1 - 0.038 14.0 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif YCII PF03795.14 RJW61166.1 - 0.048 14.1 0.1 2.9 8.3 0.0 3.3 3 0 0 3 3 3 0 YCII-related domain TagA PF12561.8 RJW61166.1 - 0.066 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain PFU PF09070.11 RJW61167.1 - 1.7e-38 131.3 0.0 3e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 RJW61167.1 - 9.5e-23 80.1 27.6 8.3e-06 26.5 0.2 8.6 9 0 0 9 9 9 6 WD domain, G-beta repeat PUL PF08324.11 RJW61167.1 - 3.1e-22 79.1 1.4 4.8e-22 78.5 1.4 1.3 1 0 0 1 1 1 1 PUL domain VPS28 PF03997.12 RJW61168.1 - 2.2e-15 56.9 1.0 3.8e-15 56.1 1.0 1.3 1 0 0 1 1 1 1 VPS28 protein DUF1652 PF07865.11 RJW61168.1 - 0.0036 17.1 0.1 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1652) DUF1593 PF07632.11 RJW61168.1 - 0.12 11.7 0.2 0.18 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) Asp_protease_2 PF13650.6 RJW61169.1 - 0.04 14.6 0.0 0.093 13.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 RJW61169.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease TPR_1 PF00515.28 RJW61170.1 - 8.7e-24 82.3 17.6 7.8e-05 22.3 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 RJW61170.1 - 7.8e-23 78.7 16.6 0.018 15.1 0.0 8.8 8 0 0 8 8 8 6 Tetratricopeptide repeat RVT_1 PF00078.27 RJW61170.1 - 2.3e-22 79.6 0.0 4.4e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_8 PF13181.6 RJW61170.1 - 6.4e-20 69.6 11.2 0.03 14.5 0.1 9.1 9 0 0 9 9 8 4 Tetratricopeptide repeat ANAPC8 PF04049.13 RJW61170.1 - 1.5e-14 54.3 0.0 3.4e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 RJW61170.1 - 3e-13 49.4 16.8 0.11 13.4 0.0 8.7 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 RJW61170.1 - 1.4e-09 38.4 17.1 0.00023 21.8 0.3 6.0 7 1 2 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW61170.1 - 2.8e-08 33.6 3.8 1.9 9.1 0.0 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 RJW61170.1 - 4.4e-08 33.5 8.7 0.3 11.6 0.1 6.2 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW61170.1 - 6.7e-08 32.7 20.6 0.02 15.2 3.4 6.7 3 2 3 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 RJW61170.1 - 2.7e-07 30.2 12.6 0.77 9.9 0.2 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 RJW61170.1 - 9.2e-07 28.3 0.4 9.4e-06 25.0 0.1 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RJW61170.1 - 2.5e-06 27.1 8.9 0.0051 16.5 0.2 4.7 4 1 1 5 5 5 2 TPR repeat TPR_10 PF13374.6 RJW61170.1 - 0.00088 19.1 4.7 15 5.6 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW61170.1 - 0.0012 19.4 17.6 4.6 8.1 0.5 7.6 9 0 0 9 9 7 1 Tetratricopeptide repeat RP-C_C PF11800.8 RJW61170.1 - 0.15 12.1 0.3 0.59 10.2 0.1 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region TPR_MalT PF17874.1 RJW61170.1 - 0.18 11.1 5.4 0.72 9.2 4.5 2.5 2 1 0 2 2 2 0 MalT-like TPR region TPR_9 PF13371.6 RJW61170.1 - 0.19 11.9 5.7 18 5.6 0.1 4.3 2 1 2 4 4 4 0 Tetratricopeptide repeat Cdc6_C PF09079.11 RJW61170.1 - 0.29 11.1 0.9 0.68 10.0 0.2 2.0 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain RPN7 PF10602.9 RJW61170.1 - 0.63 9.7 4.6 48 3.6 3.2 3.3 2 1 1 3 3 3 0 26S proteasome subunit RPN7 SNAP PF14938.6 RJW61170.1 - 1.1 8.7 8.3 0.76 9.2 3.3 2.9 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP VPS28 PF03997.12 RJW61172.1 - 1.6e-24 86.7 0.0 2.1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 VPS28 protein RVT_1 PF00078.27 RJW61174.1 - 8.8e-45 152.9 0.0 1.6e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAPS PF04499.15 RJW61174.1 - 7.5e-15 54.7 0.0 9.9e-07 27.9 0.0 3.0 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein Ank_2 PF12796.7 RJW61176.1 - 6.8e-25 87.5 0.7 3.5e-11 43.5 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW61176.1 - 2.7e-21 75.4 2.0 4.7e-08 33.1 0.5 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW61176.1 - 6.6e-20 71.2 3.4 1.7e-10 41.2 0.2 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RJW61176.1 - 2.2e-19 68.9 3.8 4.3e-06 26.9 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 RJW61176.1 - 5.9e-16 57.0 5.3 7.2e-05 22.9 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat DUF1981 PF09324.10 RJW61177.1 - 4.5e-10 39.3 0.0 2.8e-09 36.7 0.0 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Sec7 PF01369.20 RJW61177.1 - 0.00043 20.0 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Amidohydro_1 PF01979.20 RJW61179.1 - 1e-17 64.5 0.1 1.5e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RJW61179.1 - 2.5e-12 47.0 0.1 3.1e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family CAGE1 PF15066.6 RJW61180.1 - 0.23 10.1 0.1 0.3 9.7 0.1 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family RabGAP-TBC PF00566.18 RJW61181.1 - 8.7e-44 149.7 0.1 7.2e-43 146.7 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RF-1 PF00472.20 RJW61181.1 - 1.1 9.2 11.5 0.072 13.0 6.0 1.8 2 0 0 2 2 2 0 RF-1 domain RT_RNaseH PF17917.1 RJW61182.1 - 1.6e-25 89.4 0.0 2.5e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW61182.1 - 1.7e-17 63.3 0.0 3e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase OCRE PF17780.1 RJW61183.1 - 1.2e-16 60.5 12.4 3.3e-16 59.0 12.4 1.8 1 0 0 1 1 1 1 OCRE domain FHA PF00498.26 RJW61183.1 - 4.5e-14 52.5 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain G-patch PF01585.23 RJW61183.1 - 7.1e-14 51.4 0.2 1.3e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RJW61183.1 - 1.2e-07 31.7 0.2 2.5e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 G-patch domain Yop-YscD_cpl PF16697.5 RJW61183.1 - 0.00022 21.5 0.0 0.00047 20.4 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Angiomotin_C PF12240.8 RJW61183.1 - 0.012 15.1 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 Angiomotin C terminal Spc7_N PF15402.6 RJW61183.1 - 1.4 7.0 16.1 2.1 6.5 16.1 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 bZIP_2 PF07716.15 RJW61184.1 - 0.006 16.6 2.0 0.006 16.6 2.0 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 RJW61184.1 - 0.16 12.1 7.0 0.094 12.8 4.0 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF3677 PF12432.8 RJW61186.1 - 8.1e-11 42.1 0.0 2.5e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) DUF2838 PF10998.8 RJW61187.1 - 0.005 17.1 0.0 0.005 17.1 0.0 3.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) UPF0121 PF03661.13 RJW61188.1 - 1e-90 303.4 4.4 1.2e-90 303.2 4.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) MASE5 PF17178.4 RJW61188.1 - 0.14 12.0 5.1 0.44 10.4 1.6 2.2 2 0 0 2 2 2 0 Membrane-associated sensor Rab5-bind PF09311.11 RJW61191.1 - 1e-50 172.9 42.5 1e-50 172.9 42.5 2.4 2 1 0 2 2 2 1 Rabaptin-like protein FYVE PF01363.21 RJW61191.1 - 2.1e-10 40.6 7.6 2.1e-10 40.6 7.6 1.8 2 0 0 2 2 2 1 FYVE zinc finger Rabaptin PF03528.15 RJW61191.1 - 6e-08 31.8 2.1 6e-08 31.8 2.1 3.1 2 1 1 3 3 3 1 Rabaptin Filament PF00038.21 RJW61191.1 - 0.0078 15.8 4.0 0.0078 15.8 4.0 3.9 3 1 1 4 4 4 1 Intermediate filament protein DZR PF12773.7 RJW61191.1 - 0.048 13.7 8.2 1.4 9.0 5.7 2.6 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 RJW61191.1 - 0.22 11.6 4.0 0.81 9.8 4.0 2.1 1 0 0 1 1 1 0 Transposase zinc-binding domain HypA PF01155.19 RJW61191.1 - 3.1 7.8 9.4 1.9 8.5 5.2 3.0 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBR PF01485.21 RJW61191.1 - 3.3 8.0 8.6 14 6.0 8.6 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 RJW61191.1 - 6.7 7.1 13.4 6.9 7.1 11.3 2.1 2 0 0 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.6 RJW61191.1 - 8.8 6.3 13.5 2.4 8.1 9.1 2.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Lyase_aromatic PF00221.19 RJW61192.1 - 1.8e-187 623.7 1.0 2.1e-187 623.4 1.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Par3_HAL_N_term PF12053.8 RJW61192.1 - 0.0033 17.6 0.3 0.021 15.0 0.1 2.5 3 0 0 3 3 3 1 N-terminal of Par3 and HAL proteins UPF0489 PF12640.7 RJW61197.1 - 4.9e-21 75.8 0.0 9.6e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 UPF0489 domain Polyketide_cyc PF03364.20 RJW61200.1 - 0.07 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport RT_RNaseH_2 PF17919.1 RJW61201.1 - 8.6e-10 38.6 0.1 1.5e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW61201.1 - 5e-05 23.5 0.0 8.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PNPase PF03726.14 RJW61201.1 - 0.16 12.5 0.3 0.74 10.3 0.0 2.1 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain ATP-synt_ab PF00006.25 RJW61202.1 - 3.2e-74 249.2 0.0 4.7e-74 248.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 RJW61202.1 - 2e-47 160.6 2.4 3.5e-47 159.8 2.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 RJW61202.1 - 2.1e-17 63.4 1.4 5.1e-17 62.2 1.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4142 PF13628.6 RJW61202.1 - 0.032 14.4 1.1 0.062 13.5 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) HAS-barrel PF09378.10 RJW61202.1 - 0.033 14.3 0.5 0.093 12.9 0.5 1.8 1 1 0 1 1 1 0 HAS barrel domain ATPase PF06745.13 RJW61202.1 - 0.087 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC Cofac_haem_bdg PF04187.13 RJW61204.1 - 0.064 13.2 0.8 0.17 11.8 0.1 2.3 2 1 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN DUF948 PF06103.11 RJW61204.1 - 0.13 12.5 3.4 4.4 7.6 0.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SKA1 PF07160.12 RJW61204.1 - 0.17 11.7 8.3 0.083 12.7 0.2 3.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 COG2 PF06148.11 RJW61204.1 - 1.4 9.0 4.1 15 5.7 0.0 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 RJW61204.1 - 1.8 8.6 4.0 22 5.1 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 RJW61204.1 - 2 7.2 10.8 0.23 10.3 1.1 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein TAFII28 PF04719.14 RJW61206.1 - 2.4e-34 117.3 0.1 4.3e-34 116.5 0.1 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 RJW61206.1 - 0.053 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myc_N PF01056.18 RJW61206.1 - 0.056 13.3 4.4 0.076 12.9 4.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.14 RJW61206.1 - 0.058 11.7 2.2 0.066 11.5 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 RJW61206.1 - 0.063 12.7 5.0 0.077 12.4 5.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cytomega_UL84 PF06284.11 RJW61206.1 - 0.26 9.7 5.2 0.35 9.3 5.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RRN3 PF05327.11 RJW61206.1 - 7.9 4.9 7.0 9.9 4.6 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Synaptobrevin PF00957.21 RJW61208.1 - 0.026 14.3 2.2 0.042 13.6 2.2 1.2 1 0 0 1 1 1 0 Synaptobrevin ECSCR PF15820.5 RJW61208.1 - 0.17 11.7 2.1 0.33 10.8 2.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator ASFV_J13L PF05568.11 RJW61208.1 - 1.3 8.7 3.9 2.3 8.0 3.9 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein zf-C4H2 PF10146.9 RJW61210.1 - 1.2e-42 146.6 12.1 3.1e-42 145.3 12.1 1.6 1 1 0 1 1 1 1 Zinc finger-containing protein DZR PF12773.7 RJW61210.1 - 0.031 14.3 1.0 0.079 13.0 1.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 RJW61210.1 - 0.066 14.0 0.7 0.18 12.6 0.7 1.7 1 0 0 1 1 1 0 zinc-ribbon family Rogdi_lz PF10259.9 RJW61210.1 - 0.078 12.4 0.3 0.12 11.8 0.3 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein zf-C3HC4_3 PF13920.6 RJW61210.1 - 0.17 11.8 4.1 0.36 10.7 4.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 RJW61210.1 - 0.2 11.4 2.6 0.47 10.1 2.3 1.7 2 0 0 2 2 2 0 P-11 zinc finger FYVE PF01363.21 RJW61211.1 - 4.1e-17 62.1 6.0 4.1e-17 62.1 6.0 2.2 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 RJW61211.1 - 2.2e-07 31.4 0.1 0.0016 19.0 0.0 3.0 3 0 0 3 3 3 2 PH domain RhoGEF PF00621.20 RJW61211.1 - 8.4e-07 29.4 1.6 1.6e-06 28.5 1.6 1.4 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 RJW61211.1 - 0.00033 20.6 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 RJW61211.1 - 0.082 12.7 0.5 25 4.7 0.2 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain ENTH PF01417.20 RJW61211.1 - 0.092 12.8 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 ENTH domain FYVE_2 PF02318.16 RJW61211.1 - 0.29 11.3 7.8 0.078 13.2 2.4 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger HypA PF01155.19 RJW61211.1 - 1.6 8.7 5.5 1.3 9.1 1.6 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5641 PF18701.1 RJW61212.1 - 1.3e-20 73.4 0.0 3.8e-19 68.6 0.1 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5641) GYF PF02213.16 RJW61213.1 - 0.00091 18.8 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 RJW61213.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 GYF domain 2 zf-C4 PF00105.18 RJW61214.1 - 2.3e-32 111.3 14.0 4.2e-32 110.4 14.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW61214.1 - 1.9e-14 53.7 0.3 3.6e-14 52.8 0.3 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor RRM_5 PF13893.6 RJW61215.1 - 2.7e-40 136.9 5.2 9.7e-29 99.5 0.0 4.3 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RJW61215.1 - 3.7e-25 87.5 0.1 1.9e-08 34.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RJW61215.1 - 1.7e-09 37.4 0.2 0.77 9.7 0.0 4.4 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_8 PF11835.8 RJW61215.1 - 6.7e-05 23.0 0.2 0.00017 21.7 0.0 1.7 2 0 0 2 2 2 1 RRM-like domain Exo_endo_phos_2 PF14529.6 RJW61215.1 - 0.00024 20.9 0.0 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase ESR1_C PF12743.7 RJW61216.1 - 0.44 10.4 2.6 1.4 8.8 0.9 2.6 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal SDA1 PF05285.12 RJW61216.1 - 0.73 9.2 4.7 1.2 8.5 4.7 1.3 1 0 0 1 1 1 0 SDA1 KIND PF16474.5 RJW61216.1 - 0.83 9.5 4.9 0.4 10.6 1.6 2.1 2 1 0 2 2 2 0 Kinase non-catalytic C-lobe domain FERM_M PF00373.18 RJW61217.1 - 2e-32 112.0 0.0 3.9e-32 111.1 0.0 1.5 1 1 0 1 1 1 1 FERM central domain Kindlin_2_N PF18124.1 RJW61217.1 - 2e-26 92.0 0.6 4.2e-26 91.0 0.6 1.6 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain PH PF00169.29 RJW61217.1 - 6.1e-06 26.7 0.1 1.1e-05 25.9 0.1 1.4 1 0 0 1 1 1 1 PH domain FERM_N PF09379.10 RJW61217.1 - 0.013 15.4 0.0 0.071 13.1 0.0 2.2 1 1 0 1 1 1 0 FERM N-terminal domain Bax1-I PF01027.20 RJW61218.1 - 5.6e-19 68.8 31.1 2.2e-15 57.1 22.6 2.0 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 PetM PF08041.11 RJW61218.1 - 0.52 10.0 4.6 1.3 8.6 4.6 1.7 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 BEN PF10523.9 RJW61219.1 - 0.086 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 BEN domain Peptidase_A17 PF05380.13 RJW61220.1 - 2.5e-13 50.3 0.0 4.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase RNA_pol_L_2 PF13656.6 RJW61222.1 - 1.7e-25 88.6 0.0 2.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 RJW61222.1 - 9e-07 28.2 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2013 PF09431.10 RJW61222.1 - 0.084 13.0 0.0 2.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2013) Pkinase PF00069.25 RJW61223.1 - 1e-14 54.6 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61223.1 - 0.00048 19.5 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF913 PF06025.12 RJW61224.1 - 6.9e-79 265.5 0.8 6.9e-79 265.5 0.8 2.0 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) WWE PF02825.20 RJW61224.1 - 4e-09 36.9 0.0 9.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 WWE domain UBA PF00627.31 RJW61224.1 - 6.3e-07 29.2 0.3 1.9e-06 27.7 0.3 1.8 1 0 0 1 1 1 1 UBA/TS-N domain E3_UbLigase_EDD PF11547.8 RJW61224.1 - 0.034 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD SNF PF00209.18 RJW61225.1 - 9e-180 598.8 25.3 1.3e-172 575.2 19.5 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family V_ATPase_I PF01496.19 RJW61225.1 - 1.4 6.7 3.0 2.1 6.1 3.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAM_LAG1_CLN8 PF03798.16 RJW61226.1 - 3.7e-21 75.8 23.7 5.7e-21 75.2 23.7 1.3 1 0 0 1 1 1 1 TLC domain PEN-2 PF10251.9 RJW61226.1 - 0.21 12.0 9.6 0.58 10.6 1.0 3.0 2 1 1 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase WD40 PF00400.32 RJW61228.1 - 3.4e-16 59.3 9.8 0.00081 20.1 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW61228.1 - 0.0013 19.0 0.1 13 6.2 0.0 4.8 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Homeodomain PF00046.29 RJW61229.1 - 0.0048 16.7 0.7 0.013 15.4 0.7 1.7 1 0 0 1 1 1 1 Homeodomain Arm PF00514.23 RJW61232.1 - 1e-19 69.8 19.0 8.4e-05 22.5 0.0 9.1 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RJW61232.1 - 8e-17 61.4 9.8 0.0081 16.5 0.0 6.8 2 2 4 7 7 7 6 HEAT repeats HEAT PF02985.22 RJW61232.1 - 4.8e-08 32.6 20.1 0.17 12.3 0.0 8.7 8 1 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 RJW61232.1 - 5.4e-06 26.8 16.8 0.9 10.1 0.0 7.5 7 0 0 7 7 7 2 HEAT-like repeat V-ATPase_H_N PF03224.14 RJW61232.1 - 0.0002 20.7 5.3 0.12 11.6 1.3 3.3 1 1 1 2 2 2 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 RJW61232.1 - 0.00061 19.9 3.5 0.36 11.0 0.2 4.5 5 1 0 5 5 5 1 V-ATPase subunit H Cnd1 PF12717.7 RJW61232.1 - 0.0049 16.9 9.1 0.6 10.1 1.9 4.2 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF2937 PF11157.8 RJW61232.1 - 0.0072 16.1 0.4 0.022 14.5 0.1 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2937) SidE PF12252.8 RJW61232.1 - 0.073 10.6 0.2 0.11 10.0 0.2 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein MMS19_C PF12460.8 RJW61232.1 - 0.12 11.5 16.6 0.34 10.0 0.2 4.3 3 1 2 5 5 5 0 RNAPII transcription regulator C-terminal RasGEF_N_2 PF14663.6 RJW61232.1 - 0.29 11.6 8.1 21 5.5 0.2 5.0 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain IFRD PF05004.13 RJW61232.1 - 0.7 8.9 4.7 1.2 8.2 0.1 3.4 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 RJW61232.1 - 0.74 10.0 4.0 13 6.0 0.1 3.5 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 AAA PF00004.29 RJW61234.1 - 6.6e-07 29.8 0.0 7.2e-06 26.5 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RJW61234.1 - 1.9e-05 24.9 0.0 0.00035 20.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RJW61234.1 - 0.0015 18.8 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RJW61234.1 - 0.0044 17.0 0.0 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 RJW61234.1 - 0.0077 16.6 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 RJW61234.1 - 0.0079 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RJW61234.1 - 0.057 14.0 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RJW61234.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 RJW61234.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RJW61234.1 - 0.14 11.7 0.1 6.5 6.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 RJW61234.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RuvB_N PF05496.12 RJW61234.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain LRR_8 PF13855.6 RJW61235.1 - 2.7e-19 68.7 17.6 6.5e-08 32.2 7.0 3.8 2 1 1 3 3 3 3 Leucine rich repeat ig PF00047.25 RJW61235.1 - 1.6e-12 47.4 0.1 3.2e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 RJW61235.1 - 3.5e-11 43.5 0.1 1.5e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RJW61235.1 - 5.2e-11 42.5 0.0 9.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.7 RJW61235.1 - 1.7e-10 40.9 12.9 0.00092 19.6 0.9 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW61235.1 - 7.2e-07 28.9 10.6 5.1 8.0 0.0 6.2 5 0 0 5 5 5 1 Leucine Rich Repeat Ig_2 PF13895.6 RJW61235.1 - 4.5e-06 26.9 0.3 1.3e-05 25.4 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 RJW61235.1 - 0.0002 21.5 0.1 0.0018 18.4 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain TPKR_C2 PF16920.5 RJW61235.1 - 0.038 14.1 1.1 0.13 12.4 0.6 2.2 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain Izumo-Ig PF16706.5 RJW61235.1 - 0.041 13.9 0.9 0.098 12.7 0.0 2.1 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain LRR_5 PF13306.6 RJW61235.1 - 0.076 13.0 0.3 0.45 10.5 0.1 2.2 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Ig_6 PF18452.1 RJW61235.1 - 0.098 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Chordopox_A13L PF05961.11 RJW61235.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein LRR_9 PF14580.6 RJW61235.1 - 2.4 7.7 3.8 5 6.6 1.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeat M60-like_N PF17291.2 RJW61237.1 - 0.0076 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases SAM_1 PF00536.30 RJW61239.1 - 5.6e-15 55.5 0.0 8.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RJW61239.1 - 2.3e-13 50.0 0.0 4.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 RJW61239.1 - 0.003 17.5 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DUF5496 PF17600.2 RJW61239.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5496) SAM_Ste50p PF09235.10 RJW61239.1 - 0.13 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif EGF_2 PF07974.13 RJW61240.1 - 1.8e-22 79.4 120.8 6.6e-05 23.2 11.1 7.5 7 0 0 7 7 7 7 EGF-like domain EGF PF00008.27 RJW61240.1 - 2.1e-06 27.9 93.2 0.0014 18.9 3.5 7.4 7 0 0 7 7 7 6 EGF-like domain I-EGF_1 PF18372.1 RJW61240.1 - 0.00014 21.8 2.2 0.00014 21.8 2.2 7.6 9 0 0 9 9 9 3 Integrin beta epidermal growth factor like domain 1 DSL PF01414.19 RJW61240.1 - 0.01 16.1 16.7 0.01 16.1 16.7 5.8 4 1 2 6 6 6 0 Delta serrate ligand EGF_Tenascin PF18720.1 RJW61240.1 - 0.011 15.8 78.0 0.019 15.0 10.9 7.5 7 0 0 7 7 7 0 Tenascin EGF domain BSP_II PF05432.11 RJW61240.1 - 0.29 10.8 2.8 0.46 10.1 2.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Laminin_EGF PF00053.24 RJW61240.1 - 3.3 7.9 98.4 5.3 7.3 10.3 7.6 2 2 5 7 7 7 0 Laminin EGF domain LRR_8 PF13855.6 RJW61241.1 - 3.7e-57 189.9 51.6 5.1e-13 48.6 1.3 8.6 6 1 2 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 RJW61241.1 - 1.1e-40 136.9 50.7 2.1e-06 27.9 4.3 10.6 6 3 3 11 11 11 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW61241.1 - 2.6e-09 36.8 28.4 0.019 14.4 1.7 5.9 1 1 5 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 RJW61241.1 - 1.2e-08 34.3 62.8 3.8 8.4 0.2 17.5 17 3 1 18 18 18 4 Leucine Rich Repeat LRR_5 PF13306.6 RJW61241.1 - 0.02 14.9 0.1 2.4 8.2 0.1 3.3 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) CSTF_C PF14304.6 RJW61241.1 - 0.18 11.4 10.6 4 7.1 0.1 5.8 6 0 0 6 6 6 0 Transcription termination and cleavage factor C-terminal Casc1_N PF15927.5 RJW61242.1 - 1.2e-49 168.8 22.5 1.2e-49 168.8 22.5 2.6 3 0 0 3 3 3 1 Cancer susceptibility candidate 1 N-terminus EMP70 PF02990.16 RJW61244.1 - 3.2e-192 639.8 14.4 3.2e-192 639.8 14.4 1.5 2 0 0 2 2 2 1 Endomembrane protein 70 Cadherin_C_2 PF16492.5 RJW61244.1 - 0.066 14.0 1.1 12 6.7 0.0 3.4 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Shisa PF13908.6 RJW61244.1 - 0.44 10.8 1.2 42 4.3 0.0 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator FTCD_C PF04961.12 RJW61246.1 - 0.06 13.1 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase ATP-synt_J PF04911.12 RJW61246.1 - 0.22 11.2 0.5 0.36 10.4 0.5 1.3 1 0 0 1 1 1 0 ATP synthase j chain Spore_YhaL PF14147.6 RJW61246.1 - 2.9 7.7 4.4 11 5.8 0.5 2.3 2 0 0 2 2 2 0 Sporulation protein YhaL Sel1 PF08238.12 RJW61247.1 - 3.8e-15 56.0 22.8 2.8e-06 27.8 1.6 5.0 6 0 0 6 6 6 3 Sel1 repeat TPR_6 PF13174.6 RJW61247.1 - 0.19 12.5 5.7 0.44 11.3 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW61247.1 - 0.5 10.6 8.5 4.6 7.5 1.4 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PHD PF00628.29 RJW61248.1 - 8.8e-07 28.7 13.3 1.6e-06 27.9 13.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-H2C2_2 PF13465.6 RJW61248.1 - 0.24 11.9 5.1 4.2 8.0 1.3 2.7 2 0 0 2 2 2 0 Zinc-finger double domain C2-C2_1 PF11618.8 RJW61249.1 - 0.052 13.6 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 DnaJ PF00226.31 RJW61251.1 - 3.3e-17 62.3 0.9 7.9e-17 61.1 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain RAC_head PF16717.5 RJW61251.1 - 1.1e-13 52.0 0.4 4.9e-13 49.9 0.0 2.4 2 0 0 2 2 2 1 Ribosome-associated complex head domain Myb_DNA-binding PF00249.31 RJW61251.1 - 1.2e-09 38.2 0.2 6.1e-06 26.3 0.1 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RJW61251.1 - 0.044 14.0 0.1 0.54 10.6 0.1 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF1751 PF08551.10 RJW61252.1 - 5.9e-12 46.0 4.5 5.9e-12 46.0 4.5 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Nudc_N PF14050.6 RJW61253.1 - 5e-23 80.8 0.0 9.6e-23 79.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 RJW61253.1 - 1.1e-10 42.3 0.6 2.3e-10 41.4 0.6 1.5 1 0 0 1 1 1 1 CS domain Syja_N PF02383.18 RJW61254.1 - 7.5e-61 206.2 0.0 3.3e-60 204.1 0.0 2.0 1 1 0 1 1 1 1 SacI homology domain DnaJ PF00226.31 RJW61256.1 - 4.7e-27 93.9 1.1 7.8e-27 93.2 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_47 PF01532.20 RJW61257.1 - 5.3e-109 365.1 0.0 9.6e-109 364.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 zf-RING_2 PF13639.6 RJW61258.1 - 3.5e-10 40.0 4.1 3.5e-10 40.0 4.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RJW61258.1 - 5.7e-08 32.5 2.6 1.5e-07 31.2 2.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW61258.1 - 2.3e-06 27.5 0.8 5.9e-06 26.2 0.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RJW61258.1 - 6.8e-06 26.3 6.8 2.4e-05 24.5 6.8 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RJW61258.1 - 1.1e-05 25.2 3.5 2.7e-05 23.9 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RJW61258.1 - 3.4e-05 23.5 1.9 8.9e-05 22.1 1.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RJW61258.1 - 0.0016 18.3 5.0 0.0033 17.3 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RJW61258.1 - 0.0041 16.7 6.0 0.0084 15.7 6.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 RJW61258.1 - 0.0078 16.2 3.4 0.025 14.6 3.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RJW61258.1 - 0.017 15.1 3.7 0.039 14.0 3.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger D5_N PF08706.11 RJW61258.1 - 0.16 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 D5 N terminal like zf-RING_6 PF14835.6 RJW61258.1 - 0.35 10.8 1.9 1.5 8.8 2.1 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein SMC_N PF02463.19 RJW61259.1 - 7.6e-23 81.1 32.4 7.6e-23 81.1 32.4 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RJW61259.1 - 6.5e-22 78.1 0.0 3.5e-21 75.7 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 RJW61259.1 - 1.4e-05 25.1 4.6 1.4e-05 25.1 4.6 3.3 3 2 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Sec34 PF04136.15 RJW61259.1 - 0.011 15.6 4.4 0.011 15.6 4.4 8.0 6 2 2 8 8 8 0 Sec34-like family Podoplanin PF05808.11 RJW61259.1 - 0.035 14.2 1.2 0.18 11.9 1.2 2.3 1 0 0 1 1 1 0 Podoplanin Bax1-I PF01027.20 RJW61261.1 - 1e-16 61.4 21.2 1.3e-16 61.0 21.2 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Neurensin PF14927.6 RJW61261.1 - 0.035 13.8 0.8 0.035 13.8 0.8 2.0 1 1 1 2 2 2 0 Neurensin 7TMR-DISM_7TM PF07695.11 RJW61261.1 - 0.55 10.1 22.8 0.081 12.8 7.3 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4579 PF15158.6 RJW61261.1 - 5.4 6.7 6.8 0.89 9.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) Mre11_DNA_bind PF04152.14 RJW61262.1 - 1.9e-28 99.9 0.1 3.3e-28 99.1 0.1 1.4 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 RJW61262.1 - 1.5e-13 51.7 1.5 2.5e-13 51.0 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RJW61262.1 - 8e-05 22.9 0.0 0.00088 19.5 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 7tm_1 PF00001.21 RJW61265.1 - 7.7e-66 222.1 10.0 2.2e-36 125.5 3.5 2.5 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW61265.1 - 5.4e-19 68.6 5.3 1.1e-13 51.2 2.5 2.5 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RJW61265.1 - 9.3e-06 25.4 9.4 9.3e-06 25.4 9.4 3.0 3 1 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RJW61265.1 - 0.035 13.8 6.4 0.12 12.1 2.9 2.3 2 0 0 2 2 2 0 Olfactory receptor Tir_receptor_C PF07489.11 RJW61265.1 - 2.5 8.0 6.2 4.4 7.2 6.2 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF2371 PF10177.9 RJW61270.1 - 0.029 14.6 0.3 0.051 13.7 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) EGF PF00008.27 RJW61270.1 - 0.034 14.4 5.3 0.034 14.4 5.3 3.2 3 0 0 3 3 3 0 EGF-like domain FYVE PF01363.21 RJW61274.1 - 2e-19 69.5 13.4 2e-19 69.5 13.4 2.2 2 0 0 2 2 1 1 FYVE zinc finger Fez1 PF06818.15 RJW61274.1 - 0.00098 19.6 48.4 0.0058 17.1 9.7 3.4 1 1 2 3 3 3 2 Fez1 Spc7 PF08317.11 RJW61274.1 - 0.0084 15.0 48.3 0.052 12.4 9.0 3.7 1 1 0 3 3 3 3 Spc7 kinetochore protein zf_C2H2_ZHX PF18387.1 RJW61274.1 - 0.034 13.8 0.0 0.034 13.8 0.0 2.8 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Filament PF00038.21 RJW61274.1 - 0.1 12.2 44.0 0.77 9.3 9.1 3.1 1 1 1 2 2 2 0 Intermediate filament protein ADIP PF11559.8 RJW61274.1 - 0.38 10.8 55.4 0.052 13.6 2.7 5.7 2 2 4 6 6 6 0 Afadin- and alpha -actinin-Binding zf-C2H2_4 PF13894.6 RJW61274.1 - 0.39 11.7 0.1 0.39 11.7 0.1 4.0 3 1 1 4 4 4 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 RJW61274.1 - 0.5 10.3 3.4 3.2 7.7 0.1 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) FPP PF05911.11 RJW61274.1 - 1.1 7.3 56.3 0.56 8.3 11.3 3.1 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil DUF2680 PF10925.8 RJW61274.1 - 2.5 8.2 8.1 51 4.0 0.5 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2680) Pox_A_type_inc PF04508.12 RJW61274.1 - 8 6.5 10.1 16 5.5 4.5 3.7 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat Zn-ribbon_8 PF09723.10 RJW61274.1 - 8.1 6.7 12.5 25 5.1 5.1 3.7 2 1 2 4 4 4 0 Zinc ribbon domain PKcGMP_CC PF16808.5 RJW61274.1 - 9.1 6.2 12.6 0.97 9.3 0.2 4.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase 7tm_1 PF00001.21 RJW61277.1 - 9.7e-56 189.0 0.0 1.5e-55 188.4 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW61277.1 - 6.8e-06 25.6 8.5 0.0002 20.9 2.0 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RJW61277.1 - 0.00014 21.6 1.4 0.00014 21.6 1.4 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RJW61277.1 - 0.11 12.2 5.8 1.3 8.7 3.5 2.8 2 1 0 2 2 2 0 Olfactory receptor Cadherin PF00028.17 RJW61278.1 - 1.3e-68 227.4 0.2 1.3e-16 60.8 0.0 9.0 6 2 1 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RJW61278.1 - 1e-08 34.9 0.0 0.32 10.9 0.0 6.4 7 1 0 7 7 7 3 Cadherin-like RET_CLD1 PF17756.1 RJW61278.1 - 0.0013 19.0 0.0 0.44 10.8 0.0 2.9 3 0 0 3 3 3 2 RET Cadherin like domain 1 Polysacc_syn_2C PF08485.10 RJW61278.1 - 0.074 12.7 0.6 0.38 10.5 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal Acyl-CoA_dh_1 PF00441.24 RJW61280.1 - 6.6e-39 133.5 0.1 9.7e-39 133.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RJW61280.1 - 1.4e-27 95.7 0.0 2.5e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RJW61280.1 - 3.5e-22 79.2 0.0 1e-21 77.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RJW61280.1 - 8.5e-06 26.1 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 RJW61280.1 - 0.042 14.4 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Radial_spoke PF04712.12 RJW61281.1 - 1.7e-120 403.3 0.0 1.7e-120 403.3 0.0 1.7 2 0 0 2 2 2 1 Radial spokehead-like protein PGA2 PF07543.12 RJW61281.1 - 6.5 6.7 7.2 4.1 7.4 0.3 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Ribosomal_L19 PF01245.20 RJW61282.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L19 DUF2568 PF10823.8 RJW61283.1 - 0.011 16.0 0.9 0.011 16.0 0.9 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2568) YqzM PF14141.6 RJW61283.1 - 0.066 13.3 2.1 0.26 11.4 2.1 2.0 1 0 0 1 1 1 0 YqzM-like protein Pex24p PF06398.11 RJW61283.1 - 8.4 5.3 8.9 0.21 10.5 1.0 2.3 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin BAT2_N PF07001.11 RJW61284.1 - 6.7e-10 39.7 5.2 6.7e-10 39.7 5.2 10.5 8 4 4 13 13 13 1 BAT2 N-terminus Syntaxin-5_N PF11416.8 RJW61284.1 - 0.015 14.5 1.6 0.038 13.2 1.6 1.7 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain DUF2142 PF09913.9 RJW61284.1 - 0.22 10.4 0.4 0.45 9.3 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) GatB_N PF02934.15 RJW61285.1 - 1.3e-95 320.0 0.0 3.5e-95 318.5 0.0 1.6 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 RJW61285.1 - 2.4e-07 30.7 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 GatB domain Zn_Tnp_IS91 PF14319.6 RJW61285.1 - 0.012 15.6 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain Glucosamine_iso PF01182.20 RJW61286.1 - 2.9e-67 226.9 0.0 3.3e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Rubella_E2 PF05749.11 RJW61286.1 - 0.026 14.0 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 His_Phos_2 PF00328.22 RJW61289.1 - 1.3e-22 80.7 0.7 3.2e-19 69.5 0.7 2.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Trm112p PF03966.16 RJW61290.1 - 3.3e-14 53.2 0.0 4.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein His_Phos_2 PF00328.22 RJW61292.1 - 4.7e-38 131.5 3.2 4.9e-17 62.3 0.8 6.0 3 2 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) Ehbp PF10622.9 RJW61292.1 - 0.0056 16.7 0.3 0.62 10.1 0.0 2.8 3 0 0 3 3 3 1 Energy-converting hydrogenase B subunit P (EhbP) DUF4378 PF14309.6 RJW61292.1 - 0.014 15.7 1.2 0.023 15.1 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) DUF1382 PF07131.11 RJW61292.1 - 0.2 11.7 0.0 22 5.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) Tyrosinase PF00264.20 RJW61293.1 - 1.8e-34 120.0 5.0 2.6e-34 119.4 5.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.24 RJW61293.1 - 7.1 6.9 13.0 3.3 7.9 6.5 3.4 3 1 0 3 3 3 0 Laminin EGF domain RVT_1 PF00078.27 RJW61294.1 - 1.4e-32 113.1 0.0 2.3e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Recep_L_domain PF01030.24 RJW61294.1 - 1.6e-25 89.4 0.0 1.1e-11 44.9 0.0 2.4 2 0 0 2 2 2 2 Receptor L domain Furin-like PF00757.20 RJW61294.1 - 4.5e-20 72.0 35.5 1.2e-19 70.7 35.5 1.7 1 0 0 1 1 1 1 Furin-like cysteine rich region fn3 PF00041.21 RJW61294.1 - 0.0013 19.0 0.0 0.0037 17.6 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Opiods_neuropep PF01160.18 RJW61295.1 - 0.042 13.9 1.2 0.09 12.9 1.2 1.5 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide IP_trans PF02121.18 RJW61296.1 - 3.1e-112 374.1 0.2 5.3e-112 373.4 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DDHD PF02862.17 RJW61296.1 - 8.5e-33 114.4 5.0 4.5e-32 112.0 1.2 2.9 2 1 0 2 2 2 1 DDHD domain LNS2 PF08235.13 RJW61296.1 - 0.12 11.8 0.0 2.6 7.5 0.0 2.4 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) MyTH4 PF00784.17 RJW61297.1 - 2e-14 54.0 0.1 1.9e-11 44.4 0.0 3.5 2 1 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 RJW61297.1 - 2.9e-07 30.9 0.0 8.1e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 FERM central domain HDV_ag PF01517.18 RJW61297.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen TB2_DP1_HVA22 PF03134.19 RJW61298.1 - 4.1e-19 68.3 6.5 6.2e-19 67.7 6.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RITA PF17066.5 RJW61298.1 - 0.0084 15.7 1.9 1.1 8.8 0.0 2.1 2 0 0 2 2 2 2 RBPJ-interacting and tubulin associated protein Rcd1 PF04078.13 RJW61299.1 - 2.8e-121 403.7 0.3 3.8e-121 403.3 0.3 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF742 PF05331.11 RJW61299.1 - 0.14 12.0 0.0 1.8 8.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF742) DAGK_cat PF00781.24 RJW61300.1 - 1.3e-11 44.2 0.0 2.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 RJW61300.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ABC2_membrane PF01061.24 RJW61302.1 - 2.1e-35 122.1 27.1 2.1e-35 122.1 27.1 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RJW61302.1 - 1e-20 74.7 0.1 2.1e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RJW61302.1 - 2.1e-08 34.3 0.0 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RJW61302.1 - 2.7e-05 23.7 0.0 0.012 15.1 0.0 2.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RJW61302.1 - 0.00044 20.8 0.0 0.00075 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RJW61302.1 - 0.0013 18.4 1.0 0.013 15.2 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RJW61302.1 - 0.0028 17.6 0.0 0.0074 16.2 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 RJW61302.1 - 0.068 12.7 0.0 6.7 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RJW61302.1 - 0.13 12.6 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane_3 PF12698.7 RJW61302.1 - 0.2 10.7 34.4 0.62 9.1 34.6 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein DEAD PF00270.29 RJW61303.1 - 2.4e-17 63.2 0.0 4.3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.10 RJW61303.1 - 4.1e-17 62.0 0.0 7.8e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 RJW61303.1 - 3.9e-16 59.5 1.5 1.1e-15 58.1 1.5 1.8 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 RJW61303.1 - 9.4e-16 58.1 0.0 1.7e-14 54.1 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HRDC PF00570.23 RJW61303.1 - 3.1e-15 55.9 0.0 7.4e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 RJW61303.1 - 0.00034 20.7 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CLTH PF10607.9 RJW61305.1 - 1.4e-24 86.7 0.1 2.8e-24 85.7 0.1 1.6 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 RJW61305.1 - 8.3e-12 44.6 0.1 8.5e-11 41.4 0.1 2.2 2 0 0 2 2 2 1 LisH Pkinase PF00069.25 RJW61306.1 - 1.6e-36 126.0 0.0 1.9e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61306.1 - 8.7e-19 67.8 0.0 1e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RJW61306.1 - 5.7e-06 25.8 0.1 7e-06 25.5 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RJW61306.1 - 0.0001 21.9 0.1 0.00012 21.7 0.1 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RJW61306.1 - 0.00053 20.0 0.1 0.0015 18.5 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RJW61306.1 - 0.0063 16.1 0.1 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 RJW61306.1 - 0.013 14.4 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 RJW61306.1 - 0.043 12.8 0.2 0.053 12.5 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 RJW61306.1 - 0.18 11.4 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TES PF08034.11 RJW61307.1 - 2.7e-25 88.4 13.3 2.7e-25 88.4 13.3 4.7 4 1 1 5 5 5 2 Trematode eggshell synthesis protein Pkinase_Tyr PF07714.17 RJW61309.1 - 1.3e-77 260.6 0.0 2.9e-77 259.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW61309.1 - 6.3e-39 133.9 0.0 4.5e-37 127.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RJW61309.1 - 0.00058 19.3 0.0 0.00091 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW61309.1 - 0.0093 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain fn3 PF00041.21 RJW61309.1 - 0.015 15.6 0.1 11 6.5 0.1 3.6 2 1 0 2 2 2 0 Fibronectin type III domain 7tm_1 PF00001.21 RJW61311.1 - 6.8e-30 104.3 22.8 4.2e-29 101.7 18.9 2.9 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW61311.1 - 9.5e-06 25.4 13.7 9.5e-06 25.4 13.7 2.9 4 1 0 4 4 4 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RJW61311.1 - 0.0091 15.8 8.9 0.0091 15.8 8.9 1.7 2 0 0 2 2 2 1 Olfactory receptor Ctr PF04145.15 RJW61311.1 - 0.016 15.9 4.0 0.1 13.2 0.1 3.1 3 1 0 3 3 3 0 Ctr copper transporter family HCV_NS4a PF01006.20 RJW61312.1 - 0.029 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Myelin_PLP PF01275.19 RJW61315.1 - 2e-24 86.8 6.6 2.8e-24 86.3 6.6 1.1 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF4064 PF13273.6 RJW61315.1 - 0.58 10.5 5.9 0.2 12.0 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Phosphorylase PF00343.20 RJW61320.1 - 0 1106.8 0.0 0 1106.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Terpene_synth_C PF03936.16 RJW61320.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Cyclin_C_2 PF16899.5 RJW61322.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Cyclin C-terminal domain Zip PF02535.22 RJW61323.1 - 7e-35 120.8 9.8 1.7e-24 86.7 7.9 2.4 1 1 1 2 2 2 2 ZIP Zinc transporter DUF3360 PF11840.8 RJW61323.1 - 0.043 12.5 1.1 0.082 11.6 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) SAM_1 PF00536.30 RJW61324.1 - 2.9e-08 34.0 0.0 4.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RJW61324.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AA_permease PF00324.21 RJW61325.1 - 4.8e-06 25.4 6.1 5.3e-06 25.3 6.1 1.0 1 0 0 1 1 1 1 Amino acid permease CBFD_NFYB_HMF PF00808.23 RJW61326.1 - 2.4e-13 50.2 0.7 4.6e-13 49.2 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RJW61326.1 - 1.6e-07 31.7 2.1 1.9e-07 31.5 0.1 1.9 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 RJW61326.1 - 0.00044 20.4 0.2 0.00077 19.6 0.2 1.3 1 0 0 1 1 1 1 CENP-W protein Bromo_TP PF07524.13 RJW61326.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 RJW61326.1 - 0.11 13.0 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A YdjC PF04794.12 RJW61327.1 - 0.078 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 YdjC-like protein EST1 PF10374.9 RJW61328.1 - 2.1e-39 135.3 0.0 6e-39 133.8 0.0 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.9 RJW61328.1 - 2.7e-16 59.9 0.7 4.9e-16 59.0 0.7 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Forkhead PF00250.18 RJW61328.1 - 0.012 15.9 0.1 0.16 12.3 0.0 2.4 2 0 0 2 2 2 0 Forkhead domain ELMO_CED12 PF04727.13 RJW61328.1 - 0.083 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 ELMO/CED-12 family Cyclin_N PF00134.23 RJW61329.1 - 2.1e-05 24.3 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain AA_permease PF00324.21 RJW61332.1 - 2.1e-51 175.0 20.7 3e-51 174.5 20.7 1.2 1 0 0 1 1 1 1 Amino acid permease AAA PF00004.29 RJW61333.1 - 2.4e-14 53.9 0.0 4.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 RJW61333.1 - 3.5e-10 39.9 0.0 2.9e-08 33.7 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 RJW61333.1 - 4.5e-06 27.1 0.2 0.00017 22.0 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_assoc_2 PF16193.5 RJW61333.1 - 5.3e-06 26.7 0.1 1.1e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain Rad17 PF03215.15 RJW61333.1 - 6.6e-05 22.9 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 RJW61333.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW61333.1 - 0.00029 21.1 0.0 0.0098 16.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RJW61333.1 - 0.00034 20.4 0.0 0.00097 18.9 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 RJW61333.1 - 0.0004 19.8 0.0 0.0016 17.9 0.0 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rep_fac_C PF08542.11 RJW61333.1 - 0.00055 20.3 0.1 0.0017 18.7 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA_11 PF13086.6 RJW61333.1 - 0.00065 19.6 0.0 0.00083 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RJW61333.1 - 0.00068 19.7 0.0 0.0064 16.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 RJW61333.1 - 0.001 18.8 0.0 0.003 17.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 RJW61333.1 - 0.0023 17.2 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 RJW61333.1 - 0.0062 16.4 0.0 0.91 9.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_19 PF13245.6 RJW61333.1 - 0.015 15.7 0.0 0.062 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RJW61333.1 - 0.018 15.0 0.2 0.11 12.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 RJW61333.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 RJW61333.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 RJW61333.1 - 0.075 13.3 0.0 0.18 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RJW61333.1 - 0.083 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 RJW61333.1 - 0.088 13.4 0.1 0.51 10.9 0.0 2.3 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RJW61333.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RJW61333.1 - 0.15 12.5 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 RJW61333.1 - 0.16 11.0 0.0 0.38 9.8 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain TIP49 PF06068.13 RJW61333.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Abhydrolase_1 PF00561.20 RJW61334.1 - 1.5e-22 80.5 0.1 4.1e-22 79.1 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RJW61334.1 - 1.7e-18 68.0 0.0 2e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RJW61334.1 - 8.4e-10 38.3 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 RJW61334.1 - 3.6e-08 33.4 0.0 0.00015 21.5 0.0 2.5 2 1 1 3 3 3 2 PGAP1-like protein Thioesterase PF00975.20 RJW61334.1 - 1.7e-07 31.6 0.0 3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 RJW61334.1 - 1.6e-05 24.7 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.14 RJW61334.1 - 0.00014 21.5 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ndr PF03096.14 RJW61334.1 - 0.00042 19.1 0.0 0.0042 15.8 0.0 2.0 1 1 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 RJW61334.1 - 0.00044 20.1 0.0 0.0032 17.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 RJW61334.1 - 0.012 14.6 0.0 0.026 13.4 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 RJW61334.1 - 0.02 13.4 0.0 0.08 11.4 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF2974 PF11187.8 RJW61334.1 - 0.022 14.3 0.0 0.069 12.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 RJW61334.1 - 0.027 14.3 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Lipase PF00151.19 RJW61334.1 - 0.038 13.3 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 Lipase Palm_thioest PF02089.15 RJW61334.1 - 0.061 13.2 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Peptidase_S9 PF00326.21 RJW61334.1 - 0.079 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Chlorophyllase PF07224.11 RJW61334.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_4 PF08386.10 RJW61334.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein LCAT PF02450.15 RJW61334.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF498 PF04430.14 RJW61336.1 - 2.1e-19 69.6 0.0 3.8e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Sugar_tr PF00083.24 RJW61337.1 - 1.1e-62 212.4 30.2 1.7e-62 211.8 30.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW61337.1 - 1.5e-16 60.3 57.9 8.5e-14 51.2 26.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Tho2 PF11262.8 RJW61340.1 - 2.1e-94 316.1 1.8 3.5e-94 315.4 1.8 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 RJW61340.1 - 4e-39 134.8 0.0 6.9e-38 130.7 0.0 2.2 1 1 0 1 1 1 1 THO complex subunit 2 N-terminus Thoc2 PF11732.8 RJW61340.1 - 3.4e-23 81.5 0.0 1.1e-22 79.8 0.0 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit YlqD PF11068.8 RJW61340.1 - 0.093 13.1 2.9 0.25 11.7 2.9 1.7 1 0 0 1 1 1 0 YlqD protein Peptidase_C1 PF00112.23 RJW61341.1 - 1.6e-66 224.6 2.2 2e-66 224.2 2.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 RJW61341.1 - 8.1e-14 51.2 0.0 1.5e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 RJW61341.1 - 0.022 13.5 0.8 0.34 9.6 0.1 2.1 2 0 0 2 2 2 0 Peptidase C1-like family RVT_1 PF00078.27 RJW61344.1 - 8.9e-45 152.9 0.0 1.5e-44 152.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 RJW61346.1 - 1.4e-36 124.1 0.1 1.6e-19 69.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW61346.1 - 2e-05 24.6 0.1 0.054 13.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM PF05172.13 RJW61346.1 - 5.3e-05 23.1 0.1 0.043 13.8 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 RJW61346.1 - 5.8e-05 23.0 0.2 0.011 15.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 RJW61346.1 - 0.0014 18.2 0.0 0.38 10.3 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 RJW61346.1 - 0.035 13.8 0.1 5.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 RJW61346.1 - 0.11 12.4 0.0 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif FKBP_C PF00254.28 RJW61348.1 - 6.6e-12 45.6 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 RJW61348.1 - 1.6e-11 43.5 3.9 0.00042 20.0 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW61348.1 - 4e-09 35.9 3.9 0.014 15.5 1.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RJW61348.1 - 4.9e-06 27.1 0.8 0.00084 19.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RJW61348.1 - 6.8e-05 22.5 4.4 0.054 13.2 1.6 2.5 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 RJW61348.1 - 0.00014 22.3 0.2 0.00048 20.6 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RJW61348.1 - 0.00039 20.4 2.7 0.98 9.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW61348.1 - 0.00092 19.8 1.0 0.71 10.9 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RJW61348.1 - 0.0013 18.4 0.4 0.0027 17.3 0.3 1.6 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 RJW61348.1 - 0.0068 16.7 0.6 0.16 12.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW61348.1 - 0.023 15.0 3.2 5.1 7.5 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW61348.1 - 0.032 14.9 0.7 5.9 7.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RJW61348.1 - 0.044 13.9 0.1 0.044 13.9 0.1 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 RJW61348.1 - 0.054 13.6 2.1 10 6.4 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW61348.1 - 0.12 12.6 0.7 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5129 PF17173.4 RJW61348.1 - 0.3 10.2 1.6 0.46 9.5 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Rhodanese PF00581.20 RJW61350.1 - 3.3e-11 43.6 0.0 1.2e-10 41.8 0.0 1.8 1 1 1 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.6 RJW61350.1 - 0.13 12.4 0.1 0.99 9.5 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Mito_carr PF00153.27 RJW61352.1 - 3.6e-55 183.9 1.9 6.1e-23 80.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PMP22_Claudin PF00822.20 RJW61354.1 - 0.0064 16.4 0.0 0.0078 16.1 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF872 PF05915.12 RJW61354.1 - 0.019 15.1 0.3 0.027 14.7 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF2207 PF09972.9 RJW61354.1 - 0.024 13.4 0.6 0.029 13.1 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ThrE PF06738.12 RJW61354.1 - 0.046 13.1 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter Neurensin PF14927.6 RJW61354.1 - 0.052 13.3 1.5 2.9 7.6 0.1 2.1 1 1 1 2 2 2 0 Neurensin DUF4131 PF13567.6 RJW61354.1 - 0.096 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2157 PF09925.9 RJW61354.1 - 1 9.1 2.9 3.6 7.4 2.9 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) PRIMA1 PF16101.5 RJW61356.1 - 0.044 13.8 0.9 0.065 13.3 0.3 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Helicase_C PF00271.31 RJW61357.1 - 1.8e-05 25.0 0.0 5.8e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain R3H PF01424.22 RJW61357.1 - 0.001 19.0 0.0 0.0037 17.2 0.0 2.0 1 0 0 1 1 1 1 R3H domain AAA_19 PF13245.6 RJW61357.1 - 0.0036 17.6 0.0 0.0095 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW61357.1 - 0.005 17.1 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 RJW61357.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 RJW61357.1 - 0.033 13.9 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 RJW61357.1 - 0.036 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 RJW61357.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 RJW61357.1 - 0.053 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Ank PF00023.30 RJW61357.1 - 0.056 13.9 0.1 0.26 11.8 0.1 2.2 1 0 0 1 1 1 0 Ankyrin repeat PhoH PF02562.16 RJW61357.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 RJW61357.1 - 0.075 12.8 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 RJW61357.1 - 0.087 13.4 0.0 0.45 11.1 0.0 2.2 2 0 0 2 2 1 0 Ankyrin repeats (3 copies) AAA PF00004.29 RJW61357.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 RJW61357.1 - 0.15 12.1 0.0 0.53 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF4464 PF14713.6 RJW61358.1 - 1.6e-51 175.1 0.1 1.8e-51 174.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Pkinase PF00069.25 RJW61360.1 - 1e-22 80.8 0.0 1.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61360.1 - 0.00038 19.8 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ERM PF00769.19 RJW61361.1 - 3e-06 27.2 22.1 0.00091 19.1 12.0 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.15 RJW61361.1 - 5.4e-06 26.2 37.9 0.0039 16.8 20.5 2.1 1 1 1 2 2 2 2 Exonuclease VII, large subunit Rootletin PF15035.6 RJW61361.1 - 5e-05 23.4 49.6 25 4.8 9.8 6.8 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 RJW61361.1 - 0.0007 19.7 52.1 0.24 11.5 17.9 3.4 1 1 2 3 3 3 3 Afadin- and alpha -actinin-Binding ARGLU PF15346.6 RJW61361.1 - 0.0032 17.4 17.9 0.5 10.2 7.1 2.8 1 1 1 2 2 2 2 Arginine and glutamate-rich 1 Spc7 PF08317.11 RJW61361.1 - 0.0081 15.1 30.5 0.23 10.3 13.5 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein NRBF2 PF08961.10 RJW61361.1 - 0.032 13.8 31.9 1.8e+04 -17.5 31.9 5.6 1 1 0 1 1 0 0 Nuclear receptor-binding factor 2, autophagy regulator APG6_N PF17675.1 RJW61361.1 - 0.066 13.8 28.4 2.6 8.6 12.2 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4472 PF14739.6 RJW61361.1 - 0.086 13.6 24.4 3.6 8.4 9.4 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) CALCOCO1 PF07888.11 RJW61361.1 - 0.1 11.5 29.0 0.13 11.1 29.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like UPF0449 PF15136.6 RJW61361.1 - 0.11 13.0 33.0 6.1 7.4 5.3 4.7 1 1 2 3 3 2 0 Uncharacterised protein family UPF0449 Laminin_I PF06008.14 RJW61361.1 - 0.19 11.4 33.9 1.8 8.2 9.2 3.2 1 1 1 2 2 2 0 Laminin Domain I DUF4337 PF14235.6 RJW61361.1 - 0.24 11.5 12.7 20 5.3 0.7 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FUSC PF04632.12 RJW61361.1 - 0.3 9.6 15.6 0.38 9.2 15.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GAS PF13851.6 RJW61361.1 - 0.32 10.3 28.6 9.1 5.6 14.2 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 RJW61361.1 - 0.38 11.0 38.4 1.8e+04 -20.3 38.4 4.3 1 1 0 1 1 0 0 Spc24 subunit of Ndc80 LPP PF04728.13 RJW61361.1 - 0.48 10.9 39.4 5.5 7.4 4.4 5.1 1 1 2 3 3 2 0 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.12 RJW61361.1 - 0.5 10.4 27.8 4.9 7.2 10.7 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Tektin PF03148.14 RJW61361.1 - 0.53 9.0 47.1 6.8 5.3 7.9 4.5 1 1 2 3 3 2 0 Tektin family AI-2E_transport PF01594.16 RJW61361.1 - 0.58 9.3 18.0 1.8e+04 -7.2 18.0 4.0 1 1 0 1 1 0 0 AI-2E family transporter FOXP-CC PF16159.5 RJW61361.1 - 0.71 10.6 16.7 15 6.3 0.4 6.2 1 1 3 4 4 4 0 FOXP coiled-coil domain HALZ PF02183.18 RJW61361.1 - 0.87 9.9 31.5 25 5.2 0.5 6.8 1 1 6 7 7 7 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 RJW61361.1 - 1.3 9.3 27.0 11 6.3 5.9 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding M PF02370.16 RJW61361.1 - 1.5 9.6 13.6 5.7 7.8 0.0 7.4 2 1 8 12 12 9 0 M protein repeat OmpH PF03938.14 RJW61361.1 - 1.7 9.0 23.4 11 6.3 11.0 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) KASH_CCD PF14662.6 RJW61361.1 - 1.8 8.4 31.2 8.3e+02 -0.3 31.0 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH MCC-bdg_PDZ PF10506.9 RJW61361.1 - 3.3 7.8 28.8 24 5.1 1.6 5.1 1 1 3 5 5 5 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4200 PF13863.6 RJW61361.1 - 4.4 7.7 18.7 2.3 8.6 6.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) UPF0242 PF06785.11 RJW61361.1 - 5.8 7.0 32.6 33 4.5 17.6 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 RJW61361.1 - 7.1 7.3 24.1 1.8e+04 -9.7 24.1 3.2 1 1 0 1 1 0 0 Initiation control protein YabA CEP63 PF17045.5 RJW61361.1 - 7.9 6.3 30.4 6.7 6.5 5.4 3.3 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa MscS_porin PF12795.7 RJW61361.1 - 8.1 5.9 61.2 0.16 11.5 11.8 3.1 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain DUF948 PF06103.11 RJW61361.1 - 8.4 6.7 26.7 42 4.5 4.0 4.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Tho2 PF11262.8 RJW61361.1 - 9.4 5.3 29.2 7.2 5.7 7.4 3.0 1 1 2 3 3 3 0 Transcription factor/nuclear export subunit protein 2 DUF3447 PF11929.8 RJW61363.1 - 0.034 14.1 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) IBR PF01485.21 RJW61365.1 - 7.5e-17 61.3 10.5 5.4e-10 39.3 1.6 3.9 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Dynein_light PF01221.18 RJW61366.1 - 6.1e-10 39.3 0.0 7.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 LodA_N PF17990.1 RJW61366.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal FA_desaturase PF00487.24 RJW61367.1 - 7.1e-36 124.3 22.6 9.1e-36 124.0 22.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase E1_dh PF00676.20 RJW61368.1 - 2e-99 332.3 0.0 2.4e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RJW61368.1 - 9.7e-06 25.0 0.0 3.8e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 RJW61368.1 - 2.7e-05 24.0 0.0 0.00018 21.3 0.0 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pardaxin PF07425.11 RJW61368.1 - 0.31 10.7 0.7 0.78 9.4 0.7 1.6 1 0 0 1 1 1 0 Pardaxin RhoGAP PF00620.27 RJW61371.1 - 9.8e-19 67.7 0.0 2.8e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 RJW61371.1 - 1.2e-12 48.0 0.2 3.5e-12 46.4 0.2 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain TolA_bind_tri PF16331.5 RJW61371.1 - 0.096 12.8 2.9 0.12 12.5 0.2 2.5 3 0 0 3 3 3 0 TolA binding protein trimerisation FlaC_arch PF05377.11 RJW61371.1 - 0.18 12.2 0.8 0.54 10.7 0.8 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) FHA PF00498.26 RJW61372.1 - 2.1e-18 66.4 0.0 5.4e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RJW61372.1 - 2.1e-06 28.0 0.0 4.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain McyA_C PF12593.8 RJW61373.1 - 0.087 12.6 0.9 20 5.0 0.2 2.8 2 0 0 2 2 2 0 Microcystin synthetase C terminal Galactosyl_T PF01762.21 RJW61375.1 - 9.7e-07 28.8 0.1 0.013 15.4 0.1 2.3 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 RJW61375.1 - 0.0024 17.4 0.2 0.044 13.2 0.2 2.1 1 1 0 1 1 1 1 Fringe-like ig PF00047.25 RJW61376.1 - 0.035 14.3 0.0 0.072 13.3 0.0 1.5 2 0 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.6 RJW61376.1 - 0.08 13.6 0.1 0.16 12.6 0.0 1.5 1 1 1 2 2 2 0 Immunoglobulin domain RVT_1 PF00078.27 RJW61377.1 - 5.1e-41 140.6 0.0 1.9e-40 138.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW61377.1 - 1.4e-06 28.2 0.0 3.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Sterol-sensing PF12349.8 RJW61377.1 - 3.9e-05 23.5 3.8 3.9e-05 23.5 3.8 2.6 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 RJW61377.1 - 0.00097 17.3 0.6 0.0019 16.4 0.6 1.4 1 0 0 1 1 1 1 Patched family RVT_1 PF00078.27 RJW61378.1 - 2.2e-45 154.9 0.0 3.9e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW61378.1 - 2.6e-05 24.1 0.0 8.1e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW61378.1 - 0.0008 19.0 0.8 0.0016 18.0 0.8 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ScsC_N PF18312.1 RJW61381.1 - 0.043 13.6 0.3 0.078 12.8 0.3 1.3 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Myb_DNA-binding PF00249.31 RJW61381.1 - 0.093 12.9 0.2 0.24 11.6 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain GP67 PF17634.2 RJW61381.1 - 0.93 10.0 17.9 1.8 9.1 17.9 1.3 1 0 0 1 1 1 0 Gene product 67 Pkinase PF00069.25 RJW61382.1 - 2.5e-67 227.1 0.0 3.6e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61382.1 - 4.6e-35 121.1 0.0 7.1e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RJW61382.1 - 0.00011 21.7 0.1 0.00023 20.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RJW61382.1 - 0.005 15.8 0.0 0.0085 15.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RJW61382.1 - 0.006 15.9 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RJW61382.1 - 0.018 15.0 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 RJW61382.1 - 0.044 13.4 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Ig_3 PF13927.6 RJW61383.1 - 1e-30 106.2 10.3 3.8e-07 30.6 0.0 7.2 7 1 0 7 7 7 5 Immunoglobulin domain I-set PF07679.16 RJW61383.1 - 1.5e-26 92.3 0.0 2e-08 34.2 0.0 6.3 6 0 0 6 6 6 3 Immunoglobulin I-set domain ig PF00047.25 RJW61383.1 - 1.6e-16 60.3 0.8 0.00016 21.8 0.0 6.3 5 1 0 5 5 5 2 Immunoglobulin domain Ig_2 PF13895.6 RJW61383.1 - 2e-16 60.1 1.1 9.5e-05 22.7 0.0 6.6 6 0 0 6 6 6 4 Immunoglobulin domain C2-set_2 PF08205.12 RJW61383.1 - 5.2e-13 48.9 9.3 0.012 15.7 0.1 6.2 6 1 0 6 6 6 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RJW61383.1 - 4.7e-08 33.2 7.8 0.18 12.0 0.0 7.4 6 3 0 6 6 6 2 Immunoglobulin V-set domain fn3 PF00041.21 RJW61383.1 - 4.7e-07 30.1 1.4 1.5e-06 28.4 1.4 2.0 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW61383.1 - 0.0099 16.4 2.3 0.046 14.3 1.1 2.7 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PseudoU_synth_2 PF00849.22 RJW61387.1 - 1.2e-18 67.7 0.0 2.2e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase RVT_1 PF00078.27 RJW61387.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) An_peroxidase PF03098.15 RJW61388.1 - 2.3e-195 650.2 0.0 4.4e-195 649.2 0.0 1.5 1 0 0 1 1 1 1 Animal haem peroxidase RVT_1 PF00078.27 RJW61388.1 - 8.6e-35 120.2 0.0 1.4e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ig_3 PF13927.6 RJW61388.1 - 4e-18 65.8 0.0 4.3e-09 36.8 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RJW61388.1 - 8.9e-17 61.0 0.0 3.6e-07 30.2 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain LRR_8 PF13855.6 RJW61388.1 - 2.2e-16 59.4 6.9 3e-10 39.7 0.3 2.7 1 1 1 2 2 2 2 Leucine rich repeat ig PF00047.25 RJW61388.1 - 1.4e-09 38.0 0.0 0.00087 19.4 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RJW61388.1 - 2.4e-09 37.4 0.0 0.0007 19.9 0.0 3.4 2 1 0 2 2 2 2 Immunoglobulin domain LRR_4 PF12799.7 RJW61388.1 - 4e-05 23.9 6.3 0.015 15.7 0.3 4.0 3 1 0 4 4 3 1 Leucine Rich repeats (2 copies) LRRNT PF01462.18 RJW61388.1 - 0.0019 17.8 3.4 0.0071 16.0 3.4 2.1 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 RJW61388.1 - 0.0024 17.4 0.1 0.0051 16.3 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat C2-set_2 PF08205.12 RJW61388.1 - 0.0025 17.9 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain LRR_1 PF00560.33 RJW61388.1 - 0.088 13.4 0.4 1.6e+02 3.5 0.2 4.8 3 0 0 3 3 3 0 Leucine Rich Repeat V-set PF07686.17 RJW61388.1 - 0.33 11.1 1.3 5.4 7.2 0.0 3.0 3 1 0 3 3 3 0 Immunoglobulin V-set domain FlxA PF14282.6 RJW61388.1 - 0.51 10.3 4.8 1.4 8.9 4.8 1.7 1 0 0 1 1 1 0 FlxA-like protein Prefoldin_2 PF01920.20 RJW61388.1 - 0.54 10.3 7.8 0.19 11.7 2.9 2.4 2 0 0 2 2 2 0 Prefoldin subunit GPAT_N PF14829.6 RJW61389.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal EF-hand_7 PF13499.6 RJW61392.1 - 5.2e-21 74.9 4.2 1.5e-16 60.6 0.0 3.3 3 1 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW61392.1 - 1.7e-20 71.0 0.3 2.7e-06 26.5 0.1 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RJW61392.1 - 3.1e-17 61.0 2.0 0.00049 19.8 0.2 4.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 RJW61392.1 - 1.1e-12 46.9 0.2 6.4e-05 22.3 0.1 3.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RJW61392.1 - 6.6e-09 35.5 0.1 2.9e-05 23.8 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW61392.1 - 0.01 16.1 0.0 0.54 10.6 0.0 2.9 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 RJW61392.1 - 0.012 15.8 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 p25-alpha EF-hand_4 PF12763.7 RJW61392.1 - 0.082 12.9 0.1 5.2 7.1 0.0 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Utp14 PF04615.13 RJW61392.1 - 0.14 10.7 1.0 0.2 10.2 1.0 1.1 1 0 0 1 1 1 0 Utp14 protein GCIP PF13324.6 RJW61392.1 - 0.26 10.9 3.5 0.58 9.7 3.5 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 RJW61392.1 - 3.6 7.2 12.1 6.3 6.4 12.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 RJW61392.1 - 5.2 7.5 19.9 37 4.8 17.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Toxin_11 PF07473.11 RJW61394.1 - 0.027 14.6 4.9 0.071 13.2 2.0 2.3 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species His_Phos_2 PF00328.22 RJW61395.1 - 2.4e-23 83.1 0.1 1.1e-19 71.0 0.0 2.9 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) HMG_box_2 PF09011.10 RJW61396.1 - 0.0087 16.6 3.2 0.0087 16.6 3.2 1.8 2 0 0 2 2 2 1 HMG-box domain RVT_1 PF00078.27 RJW61397.1 - 4.4e-45 153.9 0.0 8.8e-45 152.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CPSF73-100_C PF11718.8 RJW61397.1 - 1.2e-42 145.9 0.3 3.3e-42 144.5 0.3 1.8 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term RMMBL PF07521.12 RJW61397.1 - 2.1e-18 66.0 0.0 5.1e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 RJW61397.1 - 2.7e-18 66.2 0.0 8.7e-18 64.6 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Collagen PF01391.18 RJW61398.1 - 1e-161 524.8 629.8 8.1e-09 35.1 22.0 20.8 2 1 12 14 14 14 12 Collagen triple helix repeat (20 copies) COLFI PF01410.18 RJW61398.1 - 2.8e-30 105.3 0.0 4.2e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.18 RJW61398.1 - 0.00041 20.6 12.0 0.00072 19.8 12.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type C domain HEM4 PF02602.15 RJW61401.1 - 5.6e-33 114.2 0.0 6.4e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD MutL PF13941.6 RJW61402.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 MutL protein CN_hydrolase PF00795.22 RJW61403.1 - 1.7e-22 80.1 0.0 2.6e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 RJW61403.1 - 6.1e-22 77.9 0.0 1.7e-21 76.4 0.0 1.6 1 1 0 1 1 1 1 NAD synthase RVT_1 PF00078.27 RJW61403.1 - 7.6e-07 28.9 0.1 4.1e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 RJW61405.1 - 5.8e-14 52.3 16.3 0.028 15.3 0.2 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW61405.1 - 0.00022 21.4 0.1 0.0047 17.2 0.0 2.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TLE_N PF03920.15 RJW61406.1 - 3.4e-18 66.0 3.3 5.2e-18 65.4 3.3 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain FliG_N PF14842.6 RJW61406.1 - 0.016 15.7 0.7 0.025 15.1 0.7 1.3 1 0 0 1 1 1 0 FliG N-terminal domain Snurportin1 PF11538.8 RJW61407.1 - 1.6e-06 28.2 0.7 1.6e-06 28.2 0.7 1.8 2 0 0 2 2 2 1 Snurportin1 IBB PF01749.20 RJW61407.1 - 0.0022 18.4 1.3 0.0047 17.3 1.3 1.5 1 0 0 1 1 1 1 Importin beta binding domain Rhabdo_M1 PF03342.13 RJW61407.1 - 0.085 12.2 0.4 0.13 11.6 0.4 1.2 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Collagen PF01391.18 RJW61410.1 - 8.1e-150 486.7 607.9 5.6e-09 35.6 26.6 20.0 3 3 9 12 12 12 8 Collagen triple helix repeat (20 copies) RVT_1 PF00078.27 RJW61413.1 - 1.9e-05 24.3 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Amidohydro_1 PF01979.20 RJW61416.1 - 3.7e-11 42.9 0.0 2.9e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 RJW61416.1 - 4.9e-05 23.0 0.0 0.012 15.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 RJW61416.1 - 0.1 13.0 1.5 1.3 9.4 0.6 2.2 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain WD40_alt PF14077.6 RJW61417.1 - 0.032 14.1 0.1 0.055 13.3 0.1 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif MICSWaP PF17018.5 RJW61417.1 - 0.06 12.9 0.5 0.098 12.2 0.5 1.4 1 1 0 1 1 1 0 Spore wall protein MAP65_ASE1 PF03999.12 RJW61418.1 - 1.7e-42 145.9 20.2 2.2e-42 145.6 20.2 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF1664 PF07889.12 RJW61418.1 - 2.9 7.9 8.0 2.5 8.2 0.4 4.1 4 2 0 5 5 5 0 Protein of unknown function (DUF1664) OmpH PF03938.14 RJW61418.1 - 6 7.2 9.3 1.6 9.1 2.4 2.8 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DASH_Dad3 PF08656.10 RJW61418.1 - 7.7 6.7 14.2 1.4 9.0 0.8 3.6 4 0 0 4 4 4 0 DASH complex subunit Dad3 Ion_trans PF00520.31 RJW61420.1 - 1.6e-46 158.6 12.7 3.1e-46 157.6 12.7 1.5 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RJW61420.1 - 1.5e-27 95.8 0.1 5.5e-27 94.0 0.1 2.1 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RJW61420.1 - 8.1e-14 51.3 5.9 8.1e-14 51.3 5.9 2.4 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 RJW61420.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain eIF-5a PF01287.20 RJW61420.1 - 0.14 12.3 0.1 0.56 10.4 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Sigma_reg_N PF13800.6 RJW61420.1 - 4.4 7.7 8.2 8.4 6.8 0.1 3.7 4 0 0 4 4 4 0 Sigma factor regulator N-terminal DUF1115 PF06544.12 RJW61422.1 - 2.4e-13 50.4 0.3 6.2e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RWD PF05773.22 RJW61422.1 - 1.8e-08 34.7 0.0 3.3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF2102 PF09875.9 RJW61422.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) 7tm_1 PF00001.21 RJW61424.1 - 1.1e-20 74.1 6.8 5.8e-19 68.4 3.0 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) OSCP PF00213.18 RJW61425.1 - 0.0075 16.4 1.8 2.6 8.2 0.0 2.3 2 0 0 2 2 2 2 ATP synthase delta (OSCP) subunit Pyr_excise PF03013.14 RJW61425.1 - 0.045 13.7 3.3 1 9.3 0.1 3.3 3 1 0 3 3 3 0 Pyrimidine dimer DNA glycosylase Imm6 PF14434.6 RJW61425.1 - 0.45 10.4 2.8 0.62 10.0 0.2 2.4 3 1 0 3 3 3 0 Immunity protein Imm6 DUF1664 PF07889.12 RJW61425.1 - 0.68 10.0 1.9 2.2 8.3 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RasGAP_C PF03836.15 RJW61425.1 - 0.94 9.6 4.6 0.38 10.9 0.3 2.5 2 2 0 2 2 2 0 RasGAP C-terminus Spectrin PF00435.21 RJW61425.1 - 1.6 9.2 4.6 31 5.1 1.3 3.7 2 2 2 4 4 4 0 Spectrin repeat Pkinase PF00069.25 RJW61426.1 - 3.5e-67 226.5 0.0 4.5e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61426.1 - 8.2e-35 120.3 0.0 1.1e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW61426.1 - 0.0017 17.2 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RJW61426.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RJW61426.1 - 0.035 13.0 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 RJW61426.1 - 0.17 11.4 1.5 2 7.9 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Kinase-like PF14531.6 RJW61426.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Usg PF06233.12 RJW61429.1 - 0.099 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Usg-like family UNC-50 PF05216.13 RJW61430.1 - 3.7e-71 239.2 21.7 5.2e-71 238.7 21.7 1.1 1 0 0 1 1 1 1 UNC-50 family RVT_1 PF00078.27 RJW61430.1 - 7.8e-08 32.1 0.1 1.4e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sec1 PF00995.23 RJW61431.1 - 3.7e-129 432.6 0.8 4.2e-129 432.4 0.8 1.0 1 0 0 1 1 1 1 Sec1 family SPACA9 PF15120.6 RJW61431.1 - 0.026 14.3 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF438 PF04282.13 RJW61431.1 - 3.8 7.5 5.3 2.5 8.1 0.1 3.3 5 0 0 5 5 5 0 Family of unknown function (DUF438) DUF5104 PF17117.5 RJW61432.1 - 0.16 12.5 0.1 0.58 10.6 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5104) Amidohydro_1 PF01979.20 RJW61433.1 - 1.4e-29 103.5 0.1 2.9e-29 102.5 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RJW61433.1 - 8.8e-15 55.1 0.1 2.4e-06 27.3 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 RJW61433.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase AP_endonuc_2 PF01261.24 RJW61433.1 - 0.025 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TatD_DNase PF01026.21 RJW61433.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 TatD related DNase Nas2_N PF18265.1 RJW61434.1 - 1.6e-29 101.7 0.1 2.3e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 RJW61434.1 - 1.1e-07 31.6 0.1 2.2e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW61434.1 - 1.3e-06 28.7 0.0 2.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW61434.1 - 0.00013 22.2 0.0 0.00031 21.0 0.0 1.7 1 1 0 1 1 1 1 PDZ domain CENP-F_leu_zip PF10473.9 RJW61434.1 - 0.037 14.0 0.5 8.9 6.3 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JIP_LZII PF16471.5 RJW61434.1 - 0.067 13.4 0.3 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Epimerase PF01370.21 RJW61437.1 - 7.9e-08 32.1 0.0 1.5e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RJW61437.1 - 9.5e-08 32.1 0.0 2.9e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 RJW61437.1 - 4.2e-05 22.7 0.0 0.012 14.6 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 RJW61437.1 - 0.00013 21.6 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 RJW61437.1 - 0.00015 20.9 0.0 0.0023 17.1 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 RJW61437.1 - 0.24 10.5 0.4 23 4.1 0.1 2.7 2 1 0 3 3 3 0 Male sterility protein RVT_1 PF00078.27 RJW61438.1 - 1.4e-41 142.5 0.0 4.3e-41 140.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 RJW61438.1 - 0.019 15.2 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 RJW61438.1 - 0.15 12.6 0.0 0.38 11.4 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Tetraspanin PF00335.20 RJW61439.1 - 1.9e-18 67.0 21.8 8.7e-18 64.9 21.6 2.0 2 1 0 2 2 2 1 Tetraspanin family Herpes_LMP1 PF05297.11 RJW61439.1 - 0.063 12.5 2.4 0.084 12.1 2.4 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Methyltransf_8 PF05148.15 RJW61440.1 - 4.9e-60 203.1 0.0 8.2e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ank_2 PF12796.7 RJW61440.1 - 1.9e-22 79.7 2.4 3.9e-18 65.8 1.4 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW61440.1 - 4.4e-20 71.5 5.1 5.9e-09 36.0 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW61440.1 - 3.5e-18 65.7 3.1 2.1e-11 44.1 0.4 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 RJW61440.1 - 9.1e-18 64.5 0.0 6.2e-17 61.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Ank PF00023.30 RJW61440.1 - 1e-16 60.5 4.3 5.1e-05 23.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RJW61440.1 - 2.3e-15 55.1 3.7 0.0012 19.1 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Pkinase PF00069.25 RJW61440.1 - 1.2e-11 44.5 0.0 2.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain MTS PF05175.14 RJW61440.1 - 0.011 15.3 0.0 3.6 7.1 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 RJW61440.1 - 0.015 15.9 0.1 0.1 13.2 0.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 RJW61440.1 - 0.43 11.3 2.1 7.5 7.3 0.3 3.3 3 1 0 3 3 2 0 Methyltransferase domain DEAD PF00270.29 RJW61441.1 - 7.4e-18 64.9 0.0 1.5e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW61441.1 - 4.6e-15 55.9 0.0 1.1e-12 48.3 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 RJW61441.1 - 6.5e-10 39.6 2.9 1.9e-09 38.1 2.9 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 RJW61441.1 - 1.5e-05 25.0 0.0 6.8e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Glutaredoxin PF00462.24 RJW61442.1 - 8.4e-16 57.9 0.0 1.7e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin zf-met PF12874.7 RJW61444.1 - 2.9e-08 33.9 6.5 0.0094 16.3 0.2 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW61444.1 - 4.5e-08 33.2 2.6 0.007 16.6 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 RJW61444.1 - 0.00032 20.7 5.9 0.0046 17.0 0.0 3.0 3 0 0 3 3 3 1 DBF zinc finger zf-C2H2_2 PF12756.7 RJW61444.1 - 0.017 15.4 2.8 6.2 7.2 0.0 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 RJW61444.1 - 0.29 12.1 3.7 58 4.9 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-U1 PF06220.12 RJW61444.1 - 0.34 10.7 6.6 2 8.3 0.0 3.4 3 0 0 3 3 3 0 U1 zinc finger NAP PF00956.18 RJW61445.1 - 8.2e-95 317.0 3.9 8.2e-95 317.0 3.9 1.6 2 0 0 2 2 1 1 Nucleosome assembly protein (NAP) CDC45 PF02724.14 RJW61445.1 - 0.0053 15.1 3.5 0.0083 14.5 3.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Sporozoite_P67 PF05642.11 RJW61445.1 - 0.043 11.9 2.0 0.071 11.2 2.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GRP PF07172.11 RJW61445.1 - 0.049 14.3 0.3 0.12 13.1 0.2 1.7 2 0 0 2 2 2 0 Glycine rich protein family Pes-10 PF07149.11 RJW61445.1 - 0.083 11.9 7.3 0.17 10.9 7.3 1.5 1 0 0 1 1 1 0 Pes-10 NOA36 PF06524.12 RJW61445.1 - 0.3 10.4 11.7 0.58 9.4 11.7 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RJW61445.1 - 0.67 8.0 12.4 1.4 7.0 12.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RJW61445.1 - 1.2 7.3 12.7 2 6.5 12.7 1.3 1 0 0 1 1 1 0 Nop14-like family SelP_N PF04592.14 RJW61445.1 - 4.7 6.5 12.3 7.5 5.9 12.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cwf_Cwc_15 PF04889.12 RJW61445.1 - 6.2 6.5 15.6 0.12 12.1 8.3 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 RJW61445.1 - 7.7 6.5 10.6 0.35 10.9 4.4 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal HSP70 PF00012.20 RJW61446.1 - 1.3e-74 251.5 0.0 1.8e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 RJW61446.1 - 0.0032 17.2 0.3 0.0071 16.1 0.3 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.13 RJW61446.1 - 0.0084 15.0 0.1 1.8 7.3 0.0 2.5 2 1 0 2 2 2 2 MreB/Mbl protein Pkinase_Tyr PF07714.17 RJW61447.1 - 1.1e-09 38.0 0.0 1.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW61447.1 - 7.2e-06 25.6 0.0 9.9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain BTB_2 PF02214.22 RJW61448.1 - 3.1e-20 72.3 0.1 5.4e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 RJW61448.1 - 0.015 15.3 0.0 0.041 14.0 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain VEK-30 PF12107.8 RJW61448.1 - 1.4 8.9 4.2 3.1 7.8 4.2 1.6 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway DASH_Dad1 PF08649.10 RJW61450.1 - 0.027 14.7 1.8 1.4 9.2 0.2 3.9 2 0 0 2 2 2 0 DASH complex subunit Dad1 TMP_2 PF06791.13 RJW61450.1 - 0.58 9.8 8.5 1.6 8.3 1.4 3.1 2 1 1 3 3 3 0 Prophage tail length tape measure protein Pkinase PF00069.25 RJW61451.1 - 2.2e-47 161.6 0.0 3.5e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61451.1 - 1.1e-19 70.8 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW61451.1 - 0.00025 21.1 0.3 0.00073 19.5 0.3 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RJW61451.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIIa PF02197.17 RJW61452.1 - 0.007 16.0 0.1 0.017 14.7 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Myosin_head PF00063.21 RJW61453.1 - 4.2e-38 131.0 0.0 1.5e-13 49.9 0.0 4.5 4 0 0 4 4 4 3 Myosin head (motor domain) PDZ_6 PF17820.1 RJW61453.1 - 8.2e-07 28.8 0.0 2.2e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain TPR_MLP1_2 PF07926.12 RJW61453.1 - 2.1e-05 24.6 45.2 0.00016 21.7 18.7 7.0 3 1 5 8 8 8 4 TPR/MLP1/MLP2-like protein PDZ PF00595.24 RJW61453.1 - 0.00019 21.7 0.0 0.00042 20.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Myosin_tail_1 PF01576.19 RJW61453.1 - 0.012 13.5 97.5 0.041 11.7 83.8 2.2 1 1 0 2 2 2 0 Myosin tail CbiA PF01656.23 RJW61453.1 - 0.076 13.1 0.0 0.56 10.3 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MAGI_u1 PF16663.5 RJW61453.1 - 0.095 12.8 2.1 13 6.0 0.2 2.7 2 0 0 2 2 2 0 Unstructured region on MAGI GIT_CC PF16559.5 RJW61453.1 - 2.5 8.0 17.3 5.4 7.0 0.3 4.8 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor MG2 PF01835.19 RJW61456.1 - 4.4e-10 39.9 0.0 1.5e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 MG2 domain A2M_BRD PF07703.14 RJW61456.1 - 0.00011 22.5 0.0 0.023 15.1 0.0 3.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain DSL PF01414.19 RJW61456.1 - 0.83 10.0 15.3 0.019 15.2 1.5 2.7 2 0 0 2 2 2 0 Delta serrate ligand BTB PF00651.31 RJW61457.1 - 7.2e-28 97.0 0.3 1.1e-26 93.3 0.1 2.3 2 0 0 2 2 2 1 BTB/POZ domain F5_F8_type_C PF00754.25 RJW61457.1 - 1.2e-16 61.0 2.8 2e-07 31.1 0.1 2.9 3 0 0 3 3 3 2 F5/8 type C domain BACK PF07707.15 RJW61457.1 - 4.4e-09 36.4 0.0 1.1e-07 31.9 0.0 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch NDK PF00334.19 RJW61458.1 - 5.6e-29 100.9 0.0 2.6e-17 63.1 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase LSDAT_euk PF18139.1 RJW61460.1 - 1.5e-38 132.7 0.2 1.2e-26 93.7 0.0 3.2 2 1 0 2 2 2 2 SLOG in TRPM LSDAT_prok PF18171.1 RJW61460.1 - 6.9e-12 45.0 0.6 0.0016 17.7 0.0 3.3 3 0 0 3 3 3 3 SLOG in TRPM, prokaryote Ion_trans PF00520.31 RJW61461.1 - 2.4e-09 36.8 6.8 3.4e-09 36.3 6.8 1.2 1 0 0 1 1 1 1 Ion transport protein DUF604 PF04646.12 RJW61461.1 - 0.0086 15.5 0.6 0.013 14.9 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 EXS PF03124.14 RJW61461.1 - 0.026 13.8 1.1 0.038 13.3 1.1 1.3 1 0 0 1 1 1 0 EXS family Fe-S_assembly PF04384.13 RJW61461.1 - 0.04 14.5 0.1 12 6.6 0.0 2.8 3 0 0 3 3 3 0 Iron-sulphur cluster assembly TraD_N PF12615.8 RJW61461.1 - 0.04 14.7 0.6 0.083 13.7 0.6 1.5 1 0 0 1 1 1 0 F sex factor protein N terminal FPP PF05911.11 RJW61461.1 - 0.043 12.0 0.0 0.056 11.6 0.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Baculo_PEP_C PF04513.12 RJW61461.1 - 0.082 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PKD_channel PF08016.12 RJW61461.1 - 0.69 8.5 6.5 1.2 7.8 6.5 1.5 1 1 0 1 1 1 0 Polycystin cation channel STATa_Ig PF18214.1 RJW61464.1 - 0.075 13.0 0.0 0.077 13.0 0.0 1.1 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain Myb_DNA-bind_4 PF13837.6 RJW61465.1 - 7.2e-09 35.9 1.3 1.3e-08 35.1 1.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RJW61465.1 - 0.0003 21.0 0.4 0.00067 19.9 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 RJW61465.1 - 0.0096 16.2 0.8 0.02 15.1 0.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RJW61465.1 - 0.039 14.1 1.5 0.067 13.4 1.5 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 RJW61465.1 - 0.078 14.0 2.3 0.18 12.8 2.3 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RJW61465.1 - 0.094 12.8 2.3 0.31 11.2 2.3 1.9 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain C12orf66_like PF09404.10 RJW61466.1 - 1.5e-17 63.6 0.0 3.9e-17 62.2 0.0 1.6 1 1 0 1 1 1 1 KICSTOR complex C12orf66 like Ten1_2 PF15490.6 RJW61466.1 - 2.3e-09 37.0 0.0 5.1e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Telomere-capping, CST complex subunit Vps54_N PF10475.9 RJW61466.1 - 0.081 12.2 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Rep_fac-A_3 PF08661.11 RJW61466.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 1 0 1 1 1 0 Replication factor A protein 3 DEAD PF00270.29 RJW61467.1 - 1.1e-42 145.8 0.0 2e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW61467.1 - 6.4e-28 97.3 0.0 1.4e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW61467.1 - 6.2e-05 23.1 0.0 9.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RJW61467.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ig_3 PF13927.6 RJW61468.1 - 4.7e-52 174.5 0.0 4.6e-12 46.4 0.0 6.4 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 RJW61468.1 - 6.9e-45 151.1 0.0 8.3e-13 48.2 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin I-set domain ig PF00047.25 RJW61468.1 - 8.5e-35 118.8 0.0 2.8e-07 30.6 0.0 5.9 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 RJW61468.1 - 1.1e-31 109.0 0.0 8.1e-08 32.5 0.0 5.9 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 RJW61468.1 - 4.9e-24 84.6 0.5 1.9e-05 24.8 0.0 8.3 5 4 0 5 5 5 4 Immunoglobulin V-set domain fn3 PF00041.21 RJW61468.1 - 1.6e-17 63.6 0.3 3.7e-07 30.4 0.0 5.5 4 1 0 4 4 4 3 Fibronectin type III domain C2-set_2 PF08205.12 RJW61468.1 - 7.6e-11 41.9 0.5 0.033 14.2 0.0 4.9 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RJW61468.1 - 2.5e-07 30.2 0.0 0.35 10.5 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain V-set_CD47 PF08204.11 RJW61468.1 - 0.0031 17.5 0.0 2.1 8.4 0.0 2.9 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain C1-set PF07654.15 RJW61468.1 - 0.065 13.6 0.0 0.87 10.0 0.0 2.9 2 0 0 2 2 2 0 Immunoglobulin C1-set domain dsrm PF00035.26 RJW61470.1 - 0.031 15.0 0.0 7.6 7.3 0.0 2.8 2 0 0 2 2 2 0 Double-stranded RNA binding motif RabGAP-TBC PF00566.18 RJW61471.1 - 3.3e-34 118.4 0.8 5.6e-34 117.7 0.2 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain C2 PF00168.30 RJW61472.1 - 5.6e-17 61.9 2.0 2.3e-07 31.0 0.3 2.7 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 RJW61472.1 - 4.7e-10 39.7 9.7 8e-05 22.8 8.3 2.5 2 0 0 2 2 2 2 FYVE-type zinc finger FYVE PF01363.21 RJW61472.1 - 0.015 15.5 6.5 0.042 14.0 6.5 1.8 1 0 0 1 1 1 0 FYVE zinc finger Zn_ribbon_17 PF17120.5 RJW61472.1 - 2.6 7.7 8.9 0.4 10.3 4.5 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type PapD-like PF14874.6 RJW61473.1 - 0.012 15.7 0.0 0.016 15.4 0.0 1.1 1 0 0 1 1 1 0 Flagellar-associated PapD-like AAA PF00004.29 RJW61475.1 - 7.5e-43 146.1 0.0 1.8e-42 144.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 RJW61475.1 - 7.2e-29 99.6 0.1 3e-28 97.6 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 RJW61475.1 - 7.6e-18 64.3 3.4 7.6e-18 64.3 3.4 2.0 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 RJW61475.1 - 5.1e-08 32.6 0.1 2.9e-07 30.2 0.0 2.3 3 0 0 3 3 2 1 AAA+ lid domain AAA_5 PF07728.14 RJW61475.1 - 2.9e-06 27.3 0.0 9.2e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RJW61475.1 - 3e-06 27.7 0.1 0.00031 21.2 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 RJW61475.1 - 2.5e-05 24.3 0.0 0.00029 20.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RJW61475.1 - 4.6e-05 23.2 0.0 0.00014 21.7 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 RJW61475.1 - 5e-05 23.1 0.0 8.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 RJW61475.1 - 6.2e-05 22.4 0.0 9.1e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 RJW61475.1 - 7.9e-05 22.8 0.6 0.00041 20.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RJW61475.1 - 0.00016 21.9 0.2 0.0099 16.2 0.0 2.7 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 RJW61475.1 - 0.00047 19.4 0.0 0.00072 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 RJW61475.1 - 0.0019 18.7 0.0 0.0051 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RJW61475.1 - 0.0024 18.2 0.1 0.01 16.2 0.0 2.2 2 1 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 RJW61475.1 - 0.0029 17.2 0.1 0.15 11.6 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RJW61475.1 - 0.0035 17.5 0.0 0.0072 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RJW61475.1 - 0.01 15.8 0.0 0.31 10.9 0.0 2.3 1 1 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 RJW61475.1 - 0.013 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 RJW61475.1 - 0.015 14.6 3.7 2.2 7.6 0.0 3.1 3 1 1 4 4 4 0 KaiC AAA_7 PF12775.7 RJW61475.1 - 0.018 14.6 0.0 0.043 13.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 RJW61475.1 - 0.019 14.7 0.0 0.062 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 RJW61475.1 - 0.021 14.6 0.3 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 RJW61475.1 - 0.026 13.8 0.9 8.1 5.6 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain AAA_17 PF13207.6 RJW61475.1 - 0.027 14.9 0.1 0.075 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 RJW61475.1 - 0.035 13.8 0.0 0.14 11.8 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 RJW61475.1 - 0.04 13.4 0.1 0.17 11.3 0.1 2.0 2 1 0 2 2 2 0 PhoH-like protein Viral_helicase1 PF01443.18 RJW61475.1 - 0.053 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 RJW61475.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 RJW61475.1 - 0.12 12.3 1.0 1.5 8.7 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Torsin PF06309.11 RJW61475.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Torsin TPR_1 PF00515.28 RJW61475.1 - 0.22 11.4 1.1 0.56 10.1 1.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DnaJ PF00226.31 RJW61476.1 - 1e-28 99.2 0.2 1.9e-28 98.3 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4735 PF15882.5 RJW61477.1 - 9.9e-76 255.0 0.1 1.2e-75 254.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) Ank_2 PF12796.7 RJW61478.1 - 6e-16 58.8 0.5 2.8e-10 40.6 0.3 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RJW61478.1 - 2.6e-15 56.1 7.2 8.2e-06 26.0 0.4 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RJW61478.1 - 1.9e-14 53.8 0.8 1.9e-08 34.7 0.3 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW61478.1 - 2.6e-13 49.9 4.4 1.6e-06 28.2 0.3 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW61478.1 - 2.4e-12 45.8 1.1 0.00091 19.5 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat CLZ PF16526.5 RJW61478.1 - 0.0027 18.0 1.9 0.008 16.5 1.9 1.8 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF760 PF05542.11 RJW61478.1 - 0.24 11.8 1.1 1.2 9.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF760) CH PF00307.31 RJW61479.1 - 1.2e-07 31.9 0.0 1.2e-06 28.6 0.0 2.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW61479.1 - 0.0074 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 RJW61479.1 - 0.13 12.3 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 CH-like domain in sperm protein Ribosomal_L38e PF01781.18 RJW61480.1 - 5.5e-21 74.4 0.2 8.2e-21 73.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family Ephrin_rec_like PF07699.13 RJW61481.1 - 1.8e-07 30.8 4.1 5.6e-05 22.8 0.3 3.5 3 0 0 3 3 3 2 Putative ephrin-receptor like MAP65_ASE1 PF03999.12 RJW61481.1 - 0.068 11.9 0.4 0.11 11.2 0.4 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HLH PF00010.26 RJW61482.1 - 3.2e-08 33.4 0.2 5.3e-08 32.7 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-U1 PF06220.12 RJW61483.1 - 3.7e-07 29.8 1.6 7.2e-07 28.9 1.6 1.5 1 0 0 1 1 1 1 U1 zinc finger RRM_1 PF00076.22 RJW61483.1 - 9.7e-07 28.5 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 RJW61483.1 - 5.7e-05 22.9 0.4 0.00011 22.0 0.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.8 RJW61483.1 - 0.0037 17.5 1.8 0.013 15.8 1.8 2.0 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Torus PF16131.5 RJW61483.1 - 0.035 14.8 0.1 0.065 13.9 0.1 1.4 1 0 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 RJW61483.1 - 0.073 13.1 1.0 0.13 12.3 1.0 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-C2H2 PF00096.26 RJW61483.1 - 0.12 12.9 1.0 0.29 11.7 1.0 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type RVT_1 PF00078.27 RJW61484.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DAO PF01266.24 RJW61485.1 - 9.9e-49 166.8 0.0 1.1e-48 166.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RJW61485.1 - 0.00084 19.5 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RJW61485.1 - 0.0023 17.2 0.0 0.0041 16.4 0.0 1.4 1 1 0 1 1 1 1 Thi4 family Mqo PF06039.15 RJW61485.1 - 0.0084 14.7 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 RJW61485.1 - 0.042 12.9 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 RJW61485.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SNF2_N PF00176.23 RJW61486.1 - 1.8e-61 207.8 0.1 4.4e-61 206.5 0.1 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 RJW61486.1 - 2.5e-18 65.7 2.4 5.8e-09 35.7 0.1 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 RJW61486.1 - 3.7e-18 65.9 0.0 1e-17 64.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDH1_2_SANT_HL1 PF18375.1 RJW61486.1 - 2.3e-16 60.2 0.6 8.8e-16 58.4 0.1 2.4 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 DUF4208 PF13907.6 RJW61486.1 - 2.1e-15 56.9 2.1 8.2e-15 55.0 2.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Cdh1_DBD_1 PF18196.1 RJW61486.1 - 0.00036 20.8 0.1 0.00036 20.8 0.1 3.3 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 Myb_DNA-binding PF00249.31 RJW61486.1 - 0.042 14.1 1.4 0.13 12.5 0.0 2.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain Ferritin PF00210.24 RJW61487.1 - 9.3e-38 129.4 4.7 1.1e-37 129.1 4.7 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 RJW61487.1 - 7.1e-06 26.5 4.2 1.3e-05 25.6 4.1 1.5 1 1 0 1 1 1 1 Rubrerythrin Codanin-1_C PF15296.6 RJW61487.1 - 0.024 14.7 1.4 0.045 13.8 1.4 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus FANCI_S3 PF14677.6 RJW61487.1 - 0.042 13.6 0.1 0.062 13.0 0.1 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 COQ7 PF03232.13 RJW61487.1 - 0.12 12.2 1.6 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Coat_F PF07875.12 RJW61487.1 - 0.17 12.1 2.2 0.69 10.2 0.0 2.7 3 1 0 3 3 3 0 Coat F domain UCH PF00443.29 RJW61488.1 - 1.8e-42 145.6 0.0 3.1e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RJW61488.1 - 4.9e-20 71.9 0.0 1.3e-10 41.7 0.0 2.9 2 0 0 2 2 2 2 DUSP domain UCH_1 PF13423.6 RJW61488.1 - 2.5e-14 53.6 4.2 1.9e-13 50.7 0.1 3.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Ogr_Delta PF04606.12 RJW61488.1 - 1.7 8.7 9.1 4.3 7.4 0.1 4.1 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger Hydantoinase_B PF02538.14 RJW61489.1 - 9.9e-204 677.5 0.1 1.4e-203 677.0 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 RJW61489.1 - 6.6e-99 330.8 0.2 1.3e-98 329.9 0.2 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 RJW61489.1 - 6.2e-56 188.9 0.2 2e-54 184.0 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region CUT PF02376.15 RJW61493.1 - 5.2e-25 87.4 0.5 4.7e-15 55.5 0.1 2.8 2 0 0 2 2 2 2 CUT domain Homeodomain PF00046.29 RJW61493.1 - 2.3e-14 52.9 0.1 5.5e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW61493.1 - 0.00097 19.0 0.2 0.0029 17.5 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain HNF-1_N PF04814.13 RJW61493.1 - 0.031 14.9 0.0 0.031 14.9 0.0 4.2 4 1 1 5 5 5 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Glyco_hydro_15 PF00723.21 RJW61495.1 - 2.8e-134 448.3 0.0 3.3e-134 448.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF3107 PF11305.8 RJW61495.1 - 0.13 12.5 0.0 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) F5_F8_type_C PF00754.25 RJW61496.1 - 1e-12 48.2 0.0 4.8e-11 42.9 0.0 2.7 3 0 0 3 3 3 2 F5/8 type C domain Homeodomain PF00046.29 RJW61498.1 - 1.4e-09 37.6 0.6 2.5e-09 36.8 0.6 1.4 1 0 0 1 1 1 1 Homeodomain DSL PF01414.19 RJW61499.1 - 4.7e-11 42.8 4.8 4.7e-11 42.8 4.8 3.7 3 1 0 3 3 3 1 Delta serrate ligand EGF PF00008.27 RJW61499.1 - 1.1e-08 35.1 44.6 2.9e-06 27.5 3.1 5.4 4 2 0 4 4 4 3 EGF-like domain hEGF PF12661.7 RJW61499.1 - 0.00025 21.6 5.3 0.00025 21.6 5.3 5.3 5 0 0 5 5 5 3 Human growth factor-like EGF EGF_2 PF07974.13 RJW61499.1 - 0.022 15.1 3.5 0.022 15.1 3.5 5.3 5 0 0 5 5 5 0 EGF-like domain ATAD4 PF15321.6 RJW61499.1 - 0.2 13.0 0.0 0.39 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 zf_ZIC PF18366.1 RJW61502.1 - 8e-15 54.7 1.0 6.5e-13 48.6 0.1 3.0 2 0 0 2 2 2 1 Zic proteins zinc finger domain zf-H2C2_2 PF13465.6 RJW61502.1 - 3.8e-14 52.4 27.9 4.2e-07 30.1 0.3 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 RJW61502.1 - 4.7e-14 52.0 36.2 0.00077 19.8 0.2 6.7 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW61502.1 - 9.1e-05 23.0 30.0 0.29 12.1 0.2 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RJW61502.1 - 0.043 14.1 8.4 0.5 10.7 1.9 4.0 1 1 1 3 3 3 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 RJW61502.1 - 0.17 12.5 10.2 36 5.1 0.0 5.1 2 2 3 5 5 5 0 FOXP coiled-coil domain zf-met PF12874.7 RJW61502.1 - 0.26 11.7 5.8 0.97 9.9 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW61502.1 - 0.26 11.6 8.2 36 4.8 0.2 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Fn_bind PF02986.14 RJW61503.1 - 0.018 14.8 0.1 0.55 10.0 0.1 2.6 2 0 0 2 2 2 0 Fibronectin binding repeat MgtE PF01769.16 RJW61505.1 - 1.8e-09 38.1 3.3 0.00025 21.4 0.0 3.2 3 0 0 3 3 3 2 Divalent cation transporter MCM PF00493.23 RJW61506.1 - 8.1e-95 316.2 0.2 1.3e-94 315.5 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RJW61506.1 - 5.4e-31 107.1 0.1 1.1e-30 106.1 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RJW61506.1 - 6.1e-23 81.1 0.6 1.3e-22 80.0 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RJW61506.1 - 2.2e-08 34.6 0.1 6.4e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RJW61506.1 - 2e-07 30.6 0.1 7.2e-07 28.8 0.0 2.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RJW61506.1 - 0.0032 17.3 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RJW61506.1 - 0.039 13.9 0.0 0.14 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RJW61506.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain CBM53 PF16760.5 RJW61507.1 - 8.2e-06 26.3 0.1 2.2e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_21 PF03370.13 RJW61507.1 - 0.00059 20.0 0.1 0.0016 18.6 0.1 1.8 1 1 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) Cadherin PF00028.17 RJW61510.1 - 4.9e-46 155.1 3.7 1.4e-09 38.2 0.0 9.2 7 3 0 7 7 7 6 Cadherin domain Cadherin_3 PF16184.5 RJW61510.1 - 2.7e-05 24.1 12.4 0.051 13.6 0.0 6.0 6 0 0 6 6 6 3 Cadherin-like Cadherin_2 PF08266.12 RJW61510.1 - 0.0067 16.2 0.0 0.37 10.6 0.0 3.9 5 0 0 5 5 5 1 Cadherin-like WD40 PF00400.32 RJW61511.1 - 2.4e-09 37.7 7.1 0.017 16.0 0.0 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW61511.1 - 0.00015 22.0 0.1 0.23 11.8 0.0 3.8 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 RJW61511.1 - 0.0025 17.8 0.1 0.11 12.6 0.1 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 RJW61511.1 - 0.0083 16.0 0.0 1.5 8.6 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Homeodomain PF00046.29 RJW61512.1 - 1.3e-20 73.0 6.1 4e-20 71.4 6.1 1.9 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 RJW61512.1 - 0.053 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Pneumo_phosprot PF02478.16 RJW61513.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein THF_DHG_CYH_C PF02882.19 RJW61514.1 - 2.4e-48 163.5 0.0 1.5e-47 160.9 0.0 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 RJW61514.1 - 2.6e-25 88.9 0.0 4.2e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 RJW61514.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Thioredoxin_16 PF18569.1 RJW61515.1 - 1.2e-17 63.7 0.3 2.4e-17 62.8 0.3 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain DnaG_DnaB_bind PF08278.11 RJW61515.1 - 0.091 13.4 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Spond_N PF06468.13 RJW61516.1 - 5.4e-40 137.6 0.0 9.4e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Spondin_N Kunitz_BPTI PF00014.23 RJW61516.1 - 3.2e-13 49.7 21.0 7.5e-09 35.7 7.1 3.5 3 1 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain WWE PF02825.20 RJW61517.1 - 5e-17 62.3 0.2 9.3e-17 61.4 0.2 1.5 1 0 0 1 1 1 1 WWE domain Sec15 PF04091.12 RJW61518.1 - 3.5e-46 158.1 0.0 3.8e-45 154.7 0.0 2.1 1 1 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF3137 PF11335.8 RJW61518.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) Ig_3 PF13927.6 RJW61522.1 - 7.6e-09 36.0 0.4 0.0092 16.6 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 RJW61522.1 - 4.8e-08 33.0 0.0 0.0007 19.6 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 RJW61522.1 - 6.7e-07 29.4 0.4 0.073 13.3 0.0 3.9 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RJW61522.1 - 1.1e-06 28.7 0.0 0.0057 16.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RJW61522.1 - 6.2e-05 23.3 0.9 1.8 9.0 0.0 3.9 3 1 0 3 3 3 2 Immunoglobulin domain Ig_6 PF18452.1 RJW61522.1 - 0.016 14.7 0.1 1.3 8.6 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin domain DUF4292 PF14125.6 RJW61522.1 - 0.054 13.2 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) Sas10 PF09368.10 RJW61528.1 - 4.9e-25 87.8 3.3 4.9e-25 87.8 3.3 1.9 2 0 0 2 2 2 1 Sas10 C-terminal domain 7TM_GPCR_Sri PF10327.9 RJW61528.1 - 0.039 13.1 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri SSF PF00474.17 RJW61529.1 - 1.2e-126 422.9 24.0 1.2e-126 422.9 24.0 1.7 2 1 0 2 2 2 1 Sodium:solute symporter family Ank_2 PF12796.7 RJW61530.1 - 1.3e-20 73.8 0.0 5e-13 49.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW61530.1 - 4.5e-15 55.8 0.0 1.3e-10 41.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW61530.1 - 1.9e-11 43.1 0.3 9.4e-05 22.5 0.0 4.4 4 0 0 4 4 3 3 Ankyrin repeat Ank PF00023.30 RJW61530.1 - 6.7e-11 42.1 1.3 0.0031 17.9 0.1 4.2 4 0 0 4 4 3 2 Ankyrin repeat Ank_5 PF13857.6 RJW61530.1 - 1.1e-10 41.5 0.2 0.00036 20.8 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) zf-RING_6 PF14835.6 RJW61530.1 - 3.8e-08 33.1 4.3 1.2e-07 31.5 4.3 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein RVT_1 PF00078.27 RJW61530.1 - 1.9e-07 30.8 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BRCT PF00533.26 RJW61530.1 - 0.00025 21.4 0.0 0.031 14.7 0.0 2.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-RING_5 PF14634.6 RJW61530.1 - 0.017 15.1 12.5 0.049 13.6 12.5 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 RJW61530.1 - 0.035 14.0 12.2 0.1 12.5 12.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RJW61530.1 - 0.14 12.0 14.0 0.33 10.8 14.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW61530.1 - 0.36 10.7 13.8 0.88 9.5 13.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EGF PF00008.27 RJW61531.1 - 0.11 12.9 6.5 0.11 12.8 4.0 2.1 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 RJW61531.1 - 0.14 12.3 3.4 0.27 11.4 3.4 1.4 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 RJW61531.1 - 5.2 7.5 6.0 9.8 6.6 6.0 1.5 1 0 0 1 1 1 0 EGF-like domain WD40 PF00400.32 RJW61532.1 - 2.3e-13 50.4 6.4 0.0011 19.8 0.0 8.5 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW61532.1 - 1.1e-05 25.7 0.0 23 5.4 0.0 5.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW61532.1 - 0.00023 20.3 0.0 0.82 8.6 0.0 4.2 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Collagen PF01391.18 RJW61533.1 - 1.3e-155 505.3 587.8 5.4e-10 38.9 28.7 19.2 2 2 11 13 13 13 10 Collagen triple helix repeat (20 copies) bZIP_1 PF00170.21 RJW61534.1 - 5.3e-08 32.8 13.3 9.9e-08 32.0 13.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RJW61534.1 - 7e-06 26.5 9.4 1.6e-05 25.4 9.4 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 RJW61534.1 - 8.2e-06 25.8 14.6 1.3e-05 25.2 14.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper HOOK PF05622.12 RJW61534.1 - 0.013 13.7 1.8 0.019 13.2 1.8 1.1 1 0 0 1 1 1 0 HOOK protein KASH_CCD PF14662.6 RJW61534.1 - 0.13 12.1 5.0 0.24 11.2 5.0 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 RJW61534.1 - 0.89 9.4 4.8 1.6 8.6 4.8 1.3 1 0 0 1 1 1 0 Septum formation initiator Homeodomain PF00046.29 RJW61535.1 - 4.8e-20 71.2 6.9 4.8e-20 71.2 6.9 2.3 3 0 0 3 3 3 1 Homeodomain rve_3 PF13683.6 RJW61536.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain rve PF00665.26 RJW61536.1 - 0.06 13.5 0.1 2.3 8.4 0.0 2.3 1 1 1 2 2 2 0 Integrase core domain DUF1040 PF06288.13 RJW61536.1 - 0.2 12.1 0.0 0.79 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) Galactosyl_T PF01762.21 RJW61537.1 - 2.8e-06 27.3 0.3 0.00087 19.2 0.3 2.2 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 RJW61537.1 - 1.9e-05 24.2 0.6 0.00021 20.8 0.6 2.2 1 1 0 1 1 1 1 Fringe-like AAA_18 PF13238.6 RJW61538.1 - 7.5e-11 42.7 0.0 8.3e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 RJW61538.1 - 1.1e-05 25.9 0.0 1.2e-05 25.7 0.0 1.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW61538.1 - 0.00065 20.1 0.0 0.00073 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 RJW61538.1 - 0.002 18.2 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 RJW61538.1 - 0.0045 17.3 0.0 0.0069 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 RJW61538.1 - 0.0054 17.0 0.0 0.0067 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RJW61538.1 - 0.0055 16.9 0.0 0.0071 16.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 RJW61538.1 - 0.0092 15.9 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NTPase RuvB_N PF05496.12 RJW61538.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RJW61538.1 - 0.013 15.8 0.1 0.017 15.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 RJW61538.1 - 0.02 14.1 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2075 PF09848.9 RJW61538.1 - 0.02 14.1 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 RJW61538.1 - 0.044 13.1 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 RJW61538.1 - 0.052 13.9 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 RJW61538.1 - 0.053 13.2 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 RJW61538.1 - 0.058 13.1 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 RJW61538.1 - 0.059 13.8 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RJW61538.1 - 0.063 12.6 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.14 RJW61538.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B YafQ_toxin PF15738.5 RJW61538.1 - 0.13 12.6 1.2 0.22 11.9 1.0 1.6 2 1 0 2 2 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ ATPase PF06745.13 RJW61538.1 - 0.16 11.3 0.2 0.29 10.5 0.2 1.3 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 RJW61538.1 - 0.16 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RJW61538.1 - 0.23 10.8 0.4 0.39 10.0 0.2 1.5 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 RJW61538.1 - 0.24 11.0 0.3 1.5 8.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain Ets PF00178.22 RJW61539.1 - 2.6e-18 66.3 0.1 5.4e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Ets-domain zf-B_box PF00643.24 RJW61540.1 - 1.4e-10 41.2 17.6 5e-09 36.2 8.4 4.9 5 0 0 5 5 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 RJW61540.1 - 2.7e-09 36.9 7.7 2.7e-09 36.9 7.7 3.4 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RJW61540.1 - 2.6e-06 27.2 12.3 2.6e-06 27.2 12.3 3.8 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW61540.1 - 2.1e-05 24.3 7.0 2.1e-05 24.3 7.0 4.0 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW61540.1 - 4.7e-05 23.6 9.8 4.7e-05 23.6 9.8 4.4 5 0 0 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 RJW61540.1 - 7.7e-05 22.6 11.0 7.7e-05 22.6 11.0 3.9 3 1 1 4 4 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RJW61540.1 - 0.00015 21.5 8.7 0.00015 21.5 8.7 4.1 5 0 0 5 5 4 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RJW61540.1 - 0.00057 19.7 8.4 0.00057 19.7 8.4 3.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 PhaP_Bmeg PF09602.10 RJW61540.1 - 0.00062 19.7 0.6 0.0013 18.7 0.6 1.5 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) zf-C3HC4_4 PF15227.6 RJW61540.1 - 0.0013 18.8 11.7 0.0013 18.8 11.7 4.2 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING SCAI PF12070.8 RJW61540.1 - 0.023 13.6 0.2 0.033 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein SCAI RVT_1 PF00078.27 RJW61541.1 - 0.00028 20.5 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RJW61543.1 - 1e-07 32.1 0.0 1.5e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RJW61543.1 - 0.00089 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 RJW61543.1 - 0.11 12.5 0.0 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase SNF2_N PF00176.23 RJW61544.1 - 5.2e-51 173.4 0.0 1.3e-50 172.1 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain ELMO_CED12 PF04727.13 RJW61544.1 - 1.4e-40 139.3 3.7 2.5e-40 138.5 3.7 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Helicase_C PF00271.31 RJW61544.1 - 4.6e-17 62.4 0.0 2.3e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RJW61544.1 - 2.2e-08 33.6 0.0 4.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 RJW61544.1 - 8.8e-07 29.1 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TrmB PF01978.19 RJW61544.1 - 0.12 12.3 1.9 4.1 7.4 0.1 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Ax_dynein_light PF10211.9 RJW61545.1 - 3.9e-50 170.4 4.2 4.5e-50 170.2 4.2 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain PLC-beta_C PF08703.10 RJW61545.1 - 0.0034 17.4 3.3 0.0034 17.4 3.3 1.7 2 0 0 2 2 2 1 PLC-beta C terminal DUF4201 PF13870.6 RJW61545.1 - 0.014 15.1 3.7 0.023 14.4 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF16 PF01519.16 RJW61545.1 - 0.23 11.9 3.0 0.27 11.8 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 bZIP_1 PF00170.21 RJW61545.1 - 0.24 11.5 3.7 0.32 11.1 2.5 1.7 1 1 1 2 2 2 0 bZIP transcription factor MIP-T3_C PF17749.1 RJW61545.1 - 0.29 11.1 5.7 2.1 8.3 6.6 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Glyco_transf_24 PF18404.1 RJW61546.1 - 3.3e-147 489.0 0.4 5e-147 488.5 0.4 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 RJW61546.1 - 6.8e-59 199.9 0.0 5.7e-58 196.9 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 RJW61546.1 - 8e-35 119.7 0.0 3.4e-34 117.7 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 RJW61546.1 - 3.4e-34 118.4 0.0 7.5e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 RJW61546.1 - 8.9e-33 112.7 0.0 4.8e-32 110.3 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 RJW61546.1 - 1.4e-27 97.0 0.0 6.4e-24 85.1 0.0 4.7 3 2 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 RJW61546.1 - 0.0001 22.0 0.1 0.00029 20.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 8 ArfGap PF01412.18 RJW61548.1 - 4.4e-25 88.0 0.2 7.7e-25 87.3 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DZR PF12773.7 RJW61548.1 - 0.16 12.1 1.3 1.9 8.6 0.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 RJW61548.1 - 0.18 12.3 0.3 0.36 11.3 0.3 1.4 1 0 0 1 1 1 0 Cytochrome c3 Cation_efflux PF01545.21 RJW61549.1 - 3.6e-46 157.4 11.1 4.5e-46 157.1 11.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 RJW61549.1 - 0.0074 16.4 1.2 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF1282 PF06930.12 RJW61549.1 - 1.7 8.4 11.1 1.1 9.1 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) DUF4231 PF14015.6 RJW61549.1 - 3.6 8.1 6.1 19 5.8 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) SUR7 PF06687.12 RJW61549.1 - 5.8 6.5 9.7 6.2 6.4 0.0 2.5 2 1 0 2 2 2 0 SUR7/PalI family DUF3504 PF12012.8 RJW61553.1 - 1.5e-16 60.7 0.0 5.4e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) AKAP2_C PF15304.6 RJW61553.1 - 0.55 9.5 14.9 0.63 9.3 10.8 2.2 1 1 1 2 2 2 0 A-kinase anchor protein 2 C-terminus Cyt-b5 PF00173.28 RJW61554.1 - 1.4e-07 31.6 0.1 3e-07 30.5 0.0 1.8 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Creatinase_N_2 PF16189.5 RJW61557.1 - 8.2e-42 143.0 0.0 1.5e-41 142.2 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 RJW61557.1 - 5.4e-37 127.5 0.0 7.3e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 RJW61557.1 - 6.4e-18 65.7 0.0 8.2e-13 49.2 0.0 2.8 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 RJW61557.1 - 7.9e-18 64.3 3.4 6.3e-17 61.4 1.7 2.6 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Zw10 PF06248.13 RJW61563.1 - 8.3e-05 21.4 1.1 0.0001 21.0 1.1 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DrsE_2 PF13686.6 RJW61563.1 - 0.0053 16.7 0.1 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 DsrE/DsrF/DrsH-like family PYRIN PF02758.16 RJW61563.1 - 0.049 13.8 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain COG2 PF06148.11 RJW61563.1 - 0.054 13.6 0.4 0.1 12.7 0.4 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cpn60_TCP1 PF00118.24 RJW61564.1 - 7.8e-89 298.5 3.6 8.7e-89 298.4 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PcfK PF14058.6 RJW61564.1 - 0.0018 18.6 0.1 0.0026 18.1 0.1 1.2 1 0 0 1 1 1 1 PcfK-like protein EcsB PF05975.12 RJW61566.1 - 0.006 15.5 6.0 0.66 8.8 0.6 2.4 2 0 0 2 2 2 2 Bacterial ABC transporter protein EcsB Herpes_glycop PF01528.16 RJW61566.1 - 0.018 13.9 1.4 1.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus glycoprotein M Sigma_reg_N PF13800.6 RJW61566.1 - 0.046 14.0 1.0 11 6.4 0.0 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4293 PF14126.6 RJW61566.1 - 0.06 13.6 2.0 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Orthopox_A43R PF06517.11 RJW61566.1 - 0.069 13.0 0.0 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Orthopoxvirus A43R protein PMP22_Claudin PF00822.20 RJW61566.1 - 0.081 12.8 1.1 5.8 6.7 0.0 2.7 3 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family Insulin_TMD PF17870.1 RJW61566.1 - 0.13 12.4 0.9 22 5.2 0.1 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment BPD_transp_1 PF00528.22 RJW61566.1 - 0.51 10.1 3.6 12 5.6 0.2 2.2 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component DUF4149 PF13664.6 RJW61566.1 - 1.6 9.1 9.2 5.2 7.4 0.1 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) Tetraspanin PF00335.20 RJW61566.1 - 1.9 8.2 6.7 8.3 6.0 0.4 2.7 3 1 0 3 3 3 0 Tetraspanin family DUF2269 PF10027.9 RJW61566.1 - 2.4 8.2 6.7 7.1 6.7 0.2 2.7 3 1 0 3 3 3 0 Predicted integral membrane protein (DUF2269) DUF3951 PF13131.6 RJW61566.1 - 2.5 8.4 6.7 18 5.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) MtN3_slv PF03083.16 RJW61566.1 - 3.7 7.7 6.4 23 5.1 0.2 3.0 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange RVT_1 PF00078.27 RJW61567.1 - 6.2e-29 101.1 0.0 7.9e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sof1 PF04158.14 RJW61569.1 - 4e-25 87.9 6.9 6.3e-25 87.3 6.9 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 RJW61569.1 - 1.8e-17 63.4 2.1 1.2e-06 29.1 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat IBR PF01485.21 RJW61569.1 - 5.6e-08 32.9 4.0 5.6e-08 32.9 4.0 3.5 3 1 0 3 3 3 1 IBR domain, a half RING-finger domain ANAPC4_WD40 PF12894.7 RJW61569.1 - 5.9e-05 23.3 0.0 4.1 7.8 0.0 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW61569.1 - 0.00039 20.4 0.3 0.62 9.9 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-RING_5 PF14634.6 RJW61569.1 - 0.012 15.6 9.7 0.012 15.6 9.7 3.5 3 0 0 3 3 3 0 zinc-RING finger domain Peptidase_M24 PF00557.24 RJW61570.1 - 1.7e-16 60.5 0.1 2.2e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 LicD PF04991.13 RJW61572.1 - 1.9e-07 31.5 0.1 0.0011 19.2 0.0 3.0 2 1 1 3 3 3 2 LicD family Rhomboid PF01694.22 RJW61573.1 - 0.056 13.4 0.5 0.091 12.8 0.5 1.6 1 1 0 1 1 1 0 Rhomboid family SOAR PF16533.5 RJW61575.1 - 7e-25 86.9 1.1 7e-25 86.9 1.1 1.7 2 0 0 2 2 2 1 STIM1 Orai1-activating region SAM_1 PF00536.30 RJW61575.1 - 2.9e-08 34.0 0.1 5.8e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RJW61575.1 - 5.6e-05 23.2 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_8 PF13833.6 RJW61579.1 - 4.7e-07 29.6 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 RJW61579.1 - 7.3e-06 26.4 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 RJW61579.1 - 4.6e-05 23.6 0.0 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.6 RJW61579.1 - 0.0009 19.0 0.0 0.83 9.8 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain DUF2949 PF11165.8 RJW61579.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2949) TPR_2 PF07719.17 RJW61580.1 - 0.67 10.2 3.0 5.4 7.4 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW61580.1 - 5 7.1 6.0 15 5.6 1.8 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat fn3 PF00041.21 RJW61581.1 - 1.2e-18 67.2 1.7 3.7e-07 30.4 0.5 5.4 4 1 0 4 4 4 3 Fibronectin type III domain WAP PF00095.21 RJW61581.1 - 1e-09 38.6 10.5 2.2e-09 37.5 10.5 1.6 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Pur_ac_phosph_N PF16656.5 RJW61581.1 - 0.0006 20.3 0.0 6.7 7.4 0.1 4.0 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RJW61581.1 - 0.0012 19.1 0.1 4.2 7.8 0.0 3.6 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III EF-hand_7 PF13499.6 RJW61581.1 - 0.18 12.3 0.0 3.2 8.3 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair Usp PF00582.26 RJW61582.1 - 0.04 14.4 0.0 0.046 14.2 0.0 1.1 1 0 0 1 1 1 0 Universal stress protein family GTP-bdg_N PF13167.6 RJW61582.1 - 0.045 14.4 0.2 0.068 13.9 0.2 1.3 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal Innexin PF00876.18 RJW61583.1 - 1.7e-101 340.0 3.6 1.3e-65 222.0 4.7 2.1 2 0 0 2 2 2 2 Innexin GP44 PF17510.2 RJW61584.1 - 0.084 13.2 0.1 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 Gene product 44 SKA1 PF07160.12 RJW61586.1 - 3.4e-06 27.1 2.0 5.1e-06 26.5 2.0 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF2076 PF09849.9 RJW61586.1 - 0.00077 19.6 0.8 0.0011 19.0 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF4618 PF15397.6 RJW61586.1 - 0.02 14.3 2.4 0.031 13.7 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) SlyX PF04102.12 RJW61586.1 - 0.051 14.2 1.9 0.082 13.5 0.9 1.9 2 0 0 2 2 2 0 SlyX DUF2681 PF10883.8 RJW61586.1 - 0.063 13.7 0.8 0.14 12.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3450 PF11932.8 RJW61586.1 - 0.076 12.3 2.2 0.12 11.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Noelin-1 PF12308.8 RJW61586.1 - 0.077 13.0 2.8 0.09 12.8 1.7 1.6 2 0 0 2 2 2 0 Neurogenesis glycoprotein DUF2798 PF11391.8 RJW61587.1 - 6.1e-08 32.6 93.6 1.8e+04 -62.1 93.6 6.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) Gly-zipper_Omp PF13488.6 RJW61587.1 - 1.4e-07 31.4 50.5 1.8e+04 -27.9 50.5 6.0 1 1 0 1 1 1 0 Glycine zipper Romo1 PF10247.9 RJW61587.1 - 0.00035 20.9 53.7 1.8e+04 -40.2 53.7 8.7 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF5455 PF17537.2 RJW61587.1 - 1.9 9.0 55.8 1.8e+04 -43.9 55.8 9.4 1 1 0 1 1 1 0 Family of unknown function (DUF5455) BTB_2 PF02214.22 RJW61588.1 - 2e-17 63.3 0.1 5.3e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 RJW61588.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain RVT_1 PF00078.27 RJW61591.1 - 5.1e-20 71.9 0.0 7.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_7 PF13499.6 RJW61593.1 - 1e-08 35.5 0.0 0.0032 17.9 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RJW61593.1 - 5.4e-07 29.0 0.0 0.0094 15.8 0.0 4.1 4 1 0 4 4 4 1 EF-hand domain EF-hand_9 PF14658.6 RJW61593.1 - 1e-06 28.9 0.0 0.0036 17.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain GPHH PF16905.5 RJW61593.1 - 0.00039 20.1 0.0 0.75 9.6 0.0 2.7 3 0 0 3 3 3 2 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 RJW61593.1 - 0.00055 19.3 0.0 3.2 7.5 0.0 4.0 5 0 0 5 5 5 1 EF hand YqeY PF09424.10 RJW61593.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.6 1 1 0 1 1 1 0 Yqey-like protein zf-C2H2 PF00096.26 RJW61594.1 - 6e-05 23.3 43.4 0.28 11.7 0.2 8.8 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 RJW61594.1 - 0.0058 16.4 1.0 0.0058 16.4 1.0 4.4 5 0 0 5 5 5 1 zinc-finger C2H2-type zf-C2HE PF16278.5 RJW61594.1 - 0.053 14.0 16.3 4.6 7.8 0.2 4.9 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 RJW61594.1 - 0.055 14.3 0.6 0.055 14.3 0.6 9.2 9 0 0 9 9 9 0 C2H2-type zinc finger XAF1_C PF18608.1 RJW61594.1 - 0.12 12.0 4.2 0.038 13.5 0.4 2.2 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain zf-C2H2_8 PF15909.5 RJW61594.1 - 0.44 10.9 17.9 0.39 11.0 0.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 RJW61594.1 - 3.9 7.9 29.1 0.37 11.1 0.3 5.0 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RJW61594.1 - 6.2 7.4 17.0 2.8 8.4 0.8 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 RJW61594.1 - 7 6.6 8.1 1.7 8.6 0.0 3.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_3rep PF18868.1 RJW61594.1 - 9.7 6.9 19.3 61 4.3 0.1 6.3 6 1 0 6 6 6 0 Zinc finger C2H2-type, 3 repeats PP1_bind PF15276.6 RJW61597.1 - 1.8e-11 44.1 7.6 9.1e-11 41.9 2.7 5.3 2 0 0 2 2 2 1 Protein phosphatase 1 binding UCH PF00443.29 RJW61602.1 - 5.1e-47 160.5 0.0 7.6e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW61602.1 - 5.2e-28 98.6 2.7 1.7e-27 96.9 2.7 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PROCN PF08083.11 RJW61604.1 - 9.3e-235 778.8 8.5 9.3e-235 778.8 8.5 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 RJW61604.1 - 4.2e-128 425.7 0.6 7.3e-128 425.0 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 RJW61604.1 - 5.3e-90 299.5 2.9 1.3e-89 298.2 2.9 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 RJW61604.1 - 1.2e-86 288.2 4.2 1.2e-86 288.2 4.2 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 RJW61604.1 - 1.7e-71 238.6 0.0 3.4e-71 237.6 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 RJW61604.1 - 9.5e-51 170.9 0.0 2.1e-50 169.7 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 RJW61604.1 - 5.1e-48 161.4 0.4 1.2e-47 160.1 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 RJW61604.1 - 8.4e-09 35.4 0.0 2.3e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease E3_UFM1_ligase PF09743.9 RJW61605.1 - 8.6e-85 284.6 0.0 1.2e-84 284.1 0.0 1.2 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 FeoC PF09012.10 RJW61605.1 - 0.023 14.7 0.0 16 5.6 0.0 3.2 4 0 0 4 4 4 0 FeoC like transcriptional regulator PAC1 PF16094.5 RJW61606.1 - 1.6e-13 50.4 2.6 5.8e-13 48.6 2.6 1.7 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 Ras PF00071.22 RJW61608.1 - 2.9e-45 153.8 0.0 3.4e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW61608.1 - 3.2e-18 66.1 0.0 4.5e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW61608.1 - 1.2e-10 41.1 0.0 1.5e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RJW61608.1 - 5.1e-05 23.2 0.2 0.00024 21.1 0.0 1.9 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 RJW61608.1 - 0.0012 18.4 0.0 0.0034 17.0 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RJW61608.1 - 0.0075 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SPC22 PF04573.12 RJW61610.1 - 2.4e-53 180.1 0.5 2.7e-53 180.0 0.5 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Homeodomain PF00046.29 RJW61612.1 - 2.5e-06 27.2 2.9 0.00093 19.0 1.0 2.8 2 0 0 2 2 2 2 Homeodomain VWA_N2 PF16164.5 RJW61612.1 - 0.032 14.4 0.1 0.086 13.0 0.1 1.7 1 0 0 1 1 1 0 VWA N-terminal AdoMetDC_leader PF08132.11 RJW61612.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-l-methionine decarboxylase leader peptide YdaS_antitoxin PF15943.5 RJW61612.1 - 0.11 12.4 0.5 0.29 11.1 0.2 1.8 1 1 1 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Usp PF00582.26 RJW61613.1 - 5.9e-25 88.4 0.0 1.1e-24 87.5 0.0 1.4 1 1 0 1 1 1 1 Universal stress protein family ASH PF15780.5 RJW61615.1 - 1.5e-12 47.5 4.2 0.019 15.2 0.0 7.4 8 0 0 8 8 8 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RJW61615.1 - 8.6e-05 22.6 0.4 0.97 9.6 0.0 4.3 4 0 0 4 4 4 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 RJW61615.1 - 0.00011 22.3 0.4 1.6 9.1 0.0 5.0 6 0 0 6 6 6 2 Transmembrane protein 131-like MYCBPAP PF14646.6 RJW61615.1 - 0.00078 18.5 0.4 0.61 9.0 0.1 2.9 3 0 0 3 3 3 2 MYCBP-associated protein family DUF916 PF06030.12 RJW61615.1 - 0.13 12.3 0.6 1 9.4 0.0 2.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF916) LIM PF00412.22 RJW61616.1 - 1.9e-30 104.9 36.3 1.6e-12 47.4 6.2 3.5 3 0 0 3 3 3 3 LIM domain PDZ PF00595.24 RJW61616.1 - 9.5e-12 45.1 0.1 1.6e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW61616.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW61616.1 - 0.0091 16.3 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Auto_anti-p27 PF06677.12 RJW61616.1 - 0.13 12.5 0.1 0.13 12.5 0.1 4.4 5 1 0 5 5 5 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C2H2 PF00096.26 RJW61619.1 - 4.4e-09 36.3 32.2 0.001 19.4 3.7 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW61619.1 - 1.1e-05 25.6 10.4 0.00022 21.5 2.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW61619.1 - 0.00012 22.6 23.4 0.26 12.2 2.4 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW61619.1 - 0.018 15.0 3.1 4.3 7.4 0.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 RJW61619.1 - 0.12 12.8 3.4 9.6 6.7 0.2 3.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Usp PF00582.26 RJW61621.1 - 2.5e-23 83.1 0.0 5.1e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 Universal stress protein family EF-hand_7 PF13499.6 RJW61622.1 - 3.4e-07 30.6 0.0 0.011 16.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW61622.1 - 4.3e-06 26.2 0.0 0.02 14.8 0.0 3.6 4 1 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 RJW61622.1 - 7.3e-06 25.7 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 RJW61622.1 - 2e-05 24.8 0.0 0.00014 22.2 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RJW61622.1 - 0.00023 20.5 0.0 0.054 13.1 0.0 3.5 5 0 0 5 5 5 1 EF hand GPHH PF16905.5 RJW61622.1 - 0.096 12.5 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated LRR_6 PF13516.6 RJW61624.1 - 4.7e-10 38.7 1.9 0.088 12.9 0.0 4.6 4 0 0 4 4 4 4 Leucine Rich repeat LRR_4 PF12799.7 RJW61624.1 - 0.0071 16.7 0.1 1.5 9.3 0.1 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW61624.1 - 0.015 15.8 0.5 43 5.2 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat AIRS_C PF02769.22 RJW61626.1 - 2.8e-23 82.8 0.0 4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 RJW61626.1 - 2.1e-05 25.1 0.1 5.9e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain RVT_1 PF00078.27 RJW61629.1 - 8.4e-06 25.5 0.0 1.8e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GST_N_3 PF13417.6 RJW61629.1 - 0.067 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RJW61629.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Pep1_7 PF17232.2 RJW61630.1 - 0.088 13.3 0.3 0.7 10.4 0.2 2.3 2 0 0 2 2 2 0 Elicitor peptide 1-7 PhnH PF05845.12 RJW61630.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) ERp29 PF07749.12 RJW61631.1 - 2e-12 47.8 0.0 3.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain DAPG_hydrolase PF18089.1 RJW61631.1 - 0.12 11.9 0.1 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 DAPG hydrolase PhiG domain zf-CCCH PF00642.24 RJW61633.1 - 4e-14 52.1 16.7 2.3e-08 33.7 2.1 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RJW61633.1 - 1.4e-06 27.9 20.9 4.3e-05 23.2 1.8 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RJW61633.1 - 0.00056 19.9 21.1 0.011 15.8 1.7 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 RJW61633.1 - 0.0013 19.2 11.7 0.057 13.9 0.2 3.4 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger EF-hand_6 PF13405.6 RJW61634.1 - 4.5e-13 48.0 0.3 1.3e-05 24.7 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RJW61634.1 - 1.7e-11 44.4 0.0 5.3e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW61634.1 - 7.5e-10 37.7 0.0 0.00037 19.8 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 RJW61634.1 - 2e-07 31.2 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RJW61634.1 - 2.2e-05 24.2 0.0 0.27 11.1 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair HeH PF12949.7 RJW61634.1 - 0.0077 15.9 0.0 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 HeH/LEM domain DUF1870 PF08965.10 RJW61634.1 - 0.028 14.5 0.1 0.17 11.9 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1870) EF-hand_13 PF17958.1 RJW61634.1 - 0.075 12.8 0.0 19 5.1 0.0 2.9 3 1 1 4 4 4 0 EF-hand domain EF-hand_5 PF13202.6 RJW61634.1 - 0.11 12.0 0.1 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 EF hand Usp PF00582.26 RJW61636.1 - 0.00069 20.1 0.0 0.00086 19.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DegQ PF08181.11 RJW61637.1 - 0.055 13.6 1.2 4.4 7.5 0.3 2.4 2 0 0 2 2 2 0 DegQ (SacQ) family Ephrin PF00812.17 RJW61638.1 - 5.2e-09 36.2 0.0 2.1e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Ephrin TPD PF14811.6 RJW61638.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif PTS_2-RNA PF01885.16 RJW61639.1 - 4.3e-59 199.6 0.0 5.9e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ribosomal_L11_N PF03946.14 RJW61640.1 - 2e-21 75.6 0.2 3.8e-21 74.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 RJW61640.1 - 2.5e-18 66.3 0.0 4.9e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain I-set PF07679.16 RJW61641.1 - 2.7e-10 40.1 0.0 5.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 RJW61641.1 - 4.2e-10 39.7 0.1 1.5e-09 37.9 0.0 2.0 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 RJW61641.1 - 2.4e-09 37.7 0.0 4.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.15 RJW61641.1 - 1.9e-06 27.9 2.3 9.4e-06 25.7 2.3 2.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain IGFBP PF00219.18 RJW61641.1 - 5.1e-06 27.0 16.8 5.1e-06 27.0 16.8 2.0 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Ig_2 PF13895.6 RJW61641.1 - 8.1e-05 22.9 0.0 0.00026 21.3 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Kazal_1 PF00050.21 RJW61641.1 - 0.00034 20.5 2.2 0.00034 20.5 2.2 2.1 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.17 RJW61641.1 - 0.0021 18.2 0.0 0.0047 17.1 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Lentivirus_VIF PF05851.11 RJW61641.1 - 0.29 10.0 2.3 0.39 9.6 2.3 1.1 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) MFS_1_like PF12832.7 RJW61642.1 - 1.4e-84 284.2 6.4 1.8e-84 283.8 6.4 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RJW61642.1 - 2.6e-25 89.1 17.9 2.3e-13 49.8 16.1 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 RJW61642.1 - 4.2e-08 32.2 15.3 0.0026 16.4 0.7 3.3 3 0 0 3 3 3 3 MFS/sugar transport protein LacY_symp PF01306.19 RJW61642.1 - 4.5e-07 29.0 19.0 0.025 13.4 4.2 3.2 3 0 0 3 3 3 3 LacY proton/sugar symporter Nuc_H_symport PF03825.16 RJW61642.1 - 9.7e-07 28.1 5.6 9.7e-07 28.1 5.6 3.1 3 0 0 3 3 3 2 Nucleoside H+ symporter MFS_3 PF05977.13 RJW61642.1 - 0.035 12.5 2.4 0.049 12.0 0.5 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector RAWUL PF16207.5 RJW61644.1 - 0.018 15.7 0.0 0.032 14.9 0.0 1.4 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Ribul_P_3_epim PF00834.19 RJW61646.1 - 8.1e-64 214.7 0.1 1.2e-63 214.1 0.1 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family DHHC PF01529.20 RJW61646.1 - 2.8e-28 98.7 4.1 5.2e-28 97.8 4.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase QRPTase_C PF01729.19 RJW61646.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DENN PF02141.21 RJW61649.1 - 5.6e-46 156.8 0.5 1.7e-45 155.2 0.3 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain SBF2 PF12335.8 RJW61649.1 - 2.6e-37 128.7 7.2 5.4e-32 111.3 1.2 3.0 2 1 1 3 3 3 2 Myotubularin protein uDENN PF03456.18 RJW61649.1 - 1.2e-12 48.3 0.8 3.8e-12 46.8 0.8 1.9 1 0 0 1 1 1 1 uDENN domain Myotub-related PF06602.14 RJW61649.1 - 7.9e-10 38.2 0.0 1.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 RJW61649.1 - 1.3e-06 28.2 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain dDENN PF03455.19 RJW61649.1 - 0.14 12.1 2.5 0.36 10.9 2.5 1.7 1 0 0 1 1 1 0 dDENN domain zinc_ribbon_16 PF17034.5 RJW61650.1 - 0.078 13.2 1.8 0.19 12.0 1.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family RVT_1 PF00078.27 RJW61651.1 - 9e-30 103.8 0.0 1.3e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4807 PF16065.5 RJW61652.1 - 2.6e-40 137.0 0.4 1.2e-37 128.4 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4807) Glycos_transf_2 PF00535.26 RJW61654.1 - 4.2e-25 88.5 0.0 5.4e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RJW61654.1 - 2.3e-10 40.8 0.0 3.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 RJW61654.1 - 0.00057 19.4 0.0 0.00073 19.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 RJW61654.1 - 0.031 14.8 0.1 0.075 13.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 zf-C2H2 PF00096.26 RJW61656.1 - 6.5e-18 64.1 67.6 0.0002 21.6 0.9 9.7 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW61656.1 - 2.9e-11 43.2 67.6 0.00048 20.7 0.5 9.5 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW61656.1 - 1.1e-08 35.1 68.0 7.1e-05 23.1 2.4 9.1 10 0 0 10 10 10 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 RJW61656.1 - 8.6e-05 22.2 2.8 8.6e-05 22.2 2.8 6.7 6 0 0 6 6 6 1 C2H2-type zinc-finger domain zf-met PF12874.7 RJW61656.1 - 0.0001 22.6 31.9 0.0034 17.7 1.0 7.1 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RJW61656.1 - 0.00012 22.0 28.1 0.0071 16.3 0.4 6.2 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW61656.1 - 0.054 13.8 30.1 0.25 11.7 0.5 7.0 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding YL1 PF05764.13 RJW61656.1 - 0.2 11.7 23.0 0.099 12.7 7.6 3.2 3 0 0 3 3 3 0 YL1 nuclear protein Actin_micro PF17003.5 RJW61656.1 - 0.49 9.5 8.8 11 5.0 5.1 3.3 1 1 0 2 2 2 0 Putative actin-like family ADK_lid PF05191.14 RJW61656.1 - 0.97 9.5 13.2 0.41 10.7 2.0 3.7 3 0 0 3 3 3 0 Adenylate kinase, active site lid EF-hand_1 PF00036.32 RJW61657.1 - 1.4e-12 46.2 1.8 1.7e-06 27.2 0.2 3.7 3 1 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RJW61657.1 - 2.9e-12 45.5 2.1 2.3e-05 24.0 0.2 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RJW61657.1 - 2.3e-10 40.8 1.0 0.00056 20.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 RJW61657.1 - 8.4e-05 22.8 0.0 0.007 16.7 0.0 2.3 1 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RJW61657.1 - 9.2e-05 22.2 4.3 0.011 15.6 1.0 3.7 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW61657.1 - 0.0062 16.0 0.8 0.11 12.1 0.2 3.0 3 0 0 3 3 3 1 EF hand FlgD PF03963.14 RJW61657.1 - 0.046 14.0 3.6 0.16 12.3 3.6 1.8 1 1 0 1 1 1 0 Flagellar hook capping protein - N-terminal region KRAP_IP3R_bind PF14722.6 RJW61657.1 - 0.053 13.3 0.4 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain CAP_GLY PF01302.25 RJW61659.1 - 6.2e-20 71.0 0.0 9.9e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Csc2 PF18320.1 RJW61659.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Csc2 Crispr KxDL PF10241.9 RJW61659.1 - 0.45 10.8 2.7 23 5.4 0.4 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Glycolytic PF00274.19 RJW61660.1 - 1.8e-181 602.5 0.0 2e-181 602.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Peptidase_S41_N PF11918.8 RJW61661.1 - 0.052 13.8 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Usp PF00582.26 RJW61664.1 - 1.3e-22 80.8 0.1 1.9e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 Universal stress protein family SurE PF01975.17 RJW61664.1 - 0.03 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Survival protein SurE F_bP_aldolase PF01116.20 RJW61664.1 - 0.12 11.9 1.7 0.17 11.3 1.7 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Peptidase_C13 PF01650.18 RJW61665.1 - 4.9e-73 245.8 7.1 1.4e-51 175.5 1.1 2.0 1 1 1 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 RJW61665.1 - 0.015 15.2 0.0 0.04 13.9 0.0 1.7 1 1 0 1 1 1 0 Caspase domain Homeodomain PF00046.29 RJW61666.1 - 2.1e-14 53.1 0.4 4.3e-14 52.1 0.4 1.5 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 RJW61666.1 - 1.2e-05 25.4 1.3 2.5e-05 24.4 1.3 1.6 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 RJW61666.1 - 9e-05 22.3 0.0 0.00086 19.2 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain 7tm_1 PF00001.21 RJW61670.1 - 1.2e-70 237.9 12.2 6.8e-70 235.4 12.2 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW61670.1 - 1.5e-12 47.5 16.4 9.7e-08 31.7 7.5 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RJW61670.1 - 4.2e-08 33.3 6.8 4.2e-08 33.3 6.8 2.6 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RJW61670.1 - 1.7e-05 24.6 11.9 1.7e-05 24.6 11.9 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Nsp3_PL2pro PF12124.8 RJW61672.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Coronavirus polyprotein cleavage domain MutS_II PF05188.17 RJW61673.1 - 0.16 12.2 0.0 0.6 10.4 0.0 1.8 1 1 0 1 1 1 0 MutS domain II Apt1 PF10351.9 RJW61675.1 - 0.022 13.6 3.6 0.029 13.2 3.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 RJW61675.1 - 0.03 13.1 0.2 0.034 12.9 0.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.16 RJW61675.1 - 0.39 9.9 2.9 0.54 9.4 2.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Hid1 PF12722.7 RJW61675.1 - 0.42 8.7 4.0 0.59 8.2 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.12 RJW61675.1 - 0.88 7.5 4.2 1 7.2 4.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NPR3 PF03666.13 RJW61675.1 - 1.3 7.7 9.1 1.7 7.3 9.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4736 PF15883.5 RJW61677.1 - 0.012 15.3 1.2 0.015 15.1 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) EphA2_TM PF14575.6 RJW61677.1 - 0.029 15.3 0.8 0.035 15.0 0.8 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 RJW61677.1 - 0.077 13.3 6.1 0.11 12.8 6.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) NICE-3 PF07406.11 RJW61677.1 - 0.61 10.1 3.0 0.73 9.8 3.0 1.1 1 0 0 1 1 1 0 NICE-3 protein TMEM154 PF15102.6 RJW61677.1 - 0.78 9.6 11.5 0.18 11.7 8.5 1.5 2 0 0 2 2 2 0 TMEM154 protein family UL42 PF17638.2 RJW61677.1 - 0.79 9.7 2.5 1.2 9.1 2.5 1.4 1 0 0 1 1 1 0 HCMV UL42 DUF4834 PF16118.5 RJW61677.1 - 1.1 10.2 8.4 1.6 9.8 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Baculo_11_kDa PF06143.11 RJW61677.1 - 1.2 8.7 9.1 2.2 7.9 9.1 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF929 PF06053.11 RJW61677.1 - 2.4 7.4 8.6 3.7 6.8 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Shisa PF13908.6 RJW61677.1 - 2.7 8.2 4.1 3.5 7.8 4.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Nnf1 PF03980.14 RJW61678.1 - 0.086 13.2 2.8 0.12 12.7 2.1 1.7 1 1 0 1 1 1 0 Nnf1 PEP-utilisers_N PF05524.13 RJW61678.1 - 0.092 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Plasmid_RAQPRD PF09686.10 RJW61678.1 - 4.5 7.6 6.7 7 6.9 1.3 2.5 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) PDZ_5 PF17817.1 RJW61679.1 - 3.9e-23 81.5 0.1 7.1e-21 74.3 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RJW61679.1 - 7e-12 45.5 0.9 1.4e-11 44.6 0.9 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW61679.1 - 0.082 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain VHL PF01847.16 RJW61681.1 - 0.094 12.6 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 VHL beta domain RVT_1 PF00078.27 RJW61684.1 - 2e-17 63.5 0.0 2.4e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NOA36 PF06524.12 RJW61684.1 - 5.9e-05 22.5 6.4 7.3e-05 22.2 6.4 1.2 1 0 0 1 1 1 1 NOA36 protein Pes-10 PF07149.11 RJW61684.1 - 0.015 14.4 5.3 0.018 14.2 5.3 1.1 1 0 0 1 1 1 0 Pes-10 RXT2_N PF08595.11 RJW61684.1 - 0.047 13.7 3.9 0.074 13.1 3.9 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TFB6 PF17110.5 RJW61684.1 - 0.071 12.8 1.9 0.098 12.4 1.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 RJW61684.1 - 0.17 10.1 7.9 0.2 9.9 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 RJW61684.1 - 0.23 10.6 21.5 0.3 10.2 21.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 RJW61684.1 - 0.32 10.7 14.9 0.5 10.0 14.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 RJW61684.1 - 0.61 9.4 6.4 0.75 9.1 6.4 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 RJW61684.1 - 0.73 9.4 9.2 1 8.9 9.2 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 RJW61684.1 - 1.7 6.8 11.5 2.1 6.5 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RJW61684.1 - 1.7 8.0 11.1 2.3 7.6 11.1 1.1 1 0 0 1 1 1 0 SDA1 DUF2796 PF10986.8 RJW61684.1 - 3.1 7.7 10.5 4.6 7.2 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SGT1 PF07093.11 RJW61684.1 - 3.6 5.9 7.1 4.4 5.6 7.1 1.1 1 0 0 1 1 1 0 SGT1 protein ANAPC15 PF15243.6 RJW61684.1 - 5.8 7.4 15.1 12 6.4 15.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Utp14 PF04615.13 RJW61684.1 - 7.9 4.9 9.8 12 4.4 9.8 1.2 1 0 0 1 1 1 0 Utp14 protein Homeodomain PF00046.29 RJW61686.1 - 8.5e-20 70.4 1.2 1.6e-19 69.4 1.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW61686.1 - 4.1e-05 23.4 0.1 0.00011 22.1 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Beta_helix_2 PF18835.1 RJW61687.1 - 0.099 12.4 0.4 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase DUF1191 PF06697.12 RJW61689.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) RVT_1 PF00078.27 RJW61690.1 - 1.1e-09 38.2 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NCBP3 PF10309.9 RJW61690.1 - 8e-09 35.2 0.2 1.8e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Pkinase_Tyr PF07714.17 RJW61691.1 - 3.9e-44 150.9 0.0 7.3e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW61691.1 - 1.8e-22 80.0 0.0 9.5e-17 61.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 RJW61691.1 - 8e-05 23.2 0.5 0.0014 19.2 0.2 3.3 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 RJW61691.1 - 0.0059 16.6 0.0 0.023 14.7 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW61691.1 - 0.05 13.9 0.2 0.84 10.0 0.2 3.3 2 0 0 2 2 2 0 Immunoglobulin domain Neur_chan_LBD PF02931.23 RJW61692.1 - 1e-48 165.6 3.3 1.7e-48 165.0 3.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW61692.1 - 1.1e-30 107.5 6.0 3.9e-27 95.8 6.0 2.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2304 PF10066.9 RJW61692.1 - 0.38 11.0 4.4 0.88 9.8 4.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DEAD PF00270.29 RJW61693.1 - 1.8e-44 151.6 0.0 3e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW61693.1 - 1.3e-28 99.5 0.0 1.2e-27 96.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 RJW61693.1 - 4.3e-24 84.6 0.1 1.5e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 GUCT (NUC152) domain CMS1 PF14617.6 RJW61693.1 - 2.1e-06 27.3 0.0 5.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 RJW61693.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RJW61693.1 - 0.00014 21.2 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 RJW61693.1 - 0.2 11.4 0.0 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Retrotran_gag_2 PF14223.6 RJW61695.1 - 3e-05 23.7 0.1 7.3e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MA3 PF02847.17 RJW61695.1 - 0.00031 20.7 0.1 0.00051 20.0 0.1 1.4 1 0 0 1 1 1 1 MA3 domain HrpB1_HrpK PF09613.10 RJW61695.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) MatE PF01554.18 RJW61696.1 - 0.036 13.7 3.1 0.27 10.9 2.1 2.1 2 0 0 2 2 2 0 MatE Tmemb_9 PF05434.11 RJW61696.1 - 0.062 13.2 4.8 0.048 13.5 1.7 2.0 2 0 0 2 2 2 0 TMEM9 DUF4736 PF15883.5 RJW61696.1 - 0.13 12.0 0.3 0.54 10.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) ECSCR PF15820.5 RJW61696.1 - 0.16 11.8 2.7 0.34 10.8 2.7 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator ODV-E18 PF10717.9 RJW61696.1 - 0.19 11.6 3.5 0.38 10.7 3.5 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 TMEM154 PF15102.6 RJW61696.1 - 8 6.4 7.3 14 5.5 7.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family zf-H2C2_2 PF13465.6 RJW61697.1 - 3e-17 62.2 34.6 1.5e-07 31.5 0.1 7.5 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.26 RJW61697.1 - 1.1e-15 57.1 55.7 4.4e-05 23.7 0.4 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW61697.1 - 8.3e-15 54.2 58.0 0.0086 16.8 0.2 8.8 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW61697.1 - 1.5e-07 31.5 40.4 0.27 11.6 0.4 7.6 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 RJW61697.1 - 0.0025 17.6 4.3 0.97 9.3 0.0 3.3 3 0 0 3 3 3 2 GAGA factor zf-C2H2_6 PF13912.6 RJW61697.1 - 0.0041 17.1 0.3 0.0041 17.1 0.3 6.8 7 0 0 7 7 7 1 C2H2-type zinc finger zf-met PF12874.7 RJW61697.1 - 0.0041 17.5 1.7 0.0041 17.5 1.7 7.4 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RJW61697.1 - 0.0051 16.5 1.2 0.0051 16.5 1.2 5.8 7 0 0 7 7 7 1 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 RJW61697.1 - 0.0086 16.8 29.1 0.28 11.9 0.1 6.4 4 2 2 6 6 6 2 Zinc finger C2H2-type, 3 repeats DUF3268 PF11672.8 RJW61697.1 - 0.26 11.6 11.1 0.64 10.4 0.8 2.7 2 1 0 2 2 2 0 zinc-finger-containing domain zf-C2HE PF16278.5 RJW61697.1 - 0.31 11.5 26.7 1.1 9.8 4.3 5.2 5 0 0 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 RJW61697.1 - 0.52 10.3 17.2 1.8 8.5 0.4 5.6 5 0 0 5 5 5 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 RJW61697.1 - 1.8 8.6 15.4 3.8 7.5 0.2 4.8 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Actin_micro PF17003.5 RJW61697.1 - 1.9 7.6 13.2 2.2 7.4 0.3 4.7 3 3 0 3 3 3 0 Putative actin-like family zf-Di19 PF05605.12 RJW61697.1 - 8.6 6.7 33.9 0.12 12.7 1.2 5.4 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding tRNA-synt_1b PF00579.25 RJW61698.1 - 0.73 9.1 4.6 4.5 6.5 1.5 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Methyltransf_4 PF02390.17 RJW61699.1 - 4.8e-45 153.1 0.0 1.1e-44 151.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Syntaxin PF00804.25 RJW61699.1 - 0.00074 19.2 2.1 0.008 15.9 0.4 2.2 2 0 0 2 2 2 1 Syntaxin Methyltransf_12 PF08242.12 RJW61699.1 - 0.00086 20.0 0.0 0.0029 18.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW61699.1 - 0.0012 18.7 0.0 0.0043 16.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW61699.1 - 0.0023 18.6 0.0 0.0064 17.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain SNARE PF05739.19 RJW61699.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 RJW61699.1 - 0.009 15.2 0.1 0.022 14.0 0.1 1.7 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Methyltransf_11 PF08241.12 RJW61699.1 - 0.027 15.1 0.0 0.12 13.0 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain MTS PF05175.14 RJW61699.1 - 0.029 13.9 0.0 0.077 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 RJW61699.1 - 0.064 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Glyco_transf_8C PF08437.10 RJW61699.1 - 0.15 12.1 0.0 8.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal RPN6_N PF18055.1 RJW61699.1 - 0.16 12.3 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain bPH_3 PF14470.6 RJW61707.1 - 0.019 15.3 0.1 0.031 14.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial PH domain IRS PF02174.17 RJW61708.1 - 1.6e-16 60.0 0.0 3.1e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) IBR PF01485.21 RJW61710.1 - 2.2e-23 82.2 42.2 4.7e-14 52.3 7.3 4.7 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 RJW61710.1 - 0.0055 16.6 8.5 0.0055 16.6 8.5 4.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 RJW61710.1 - 0.03 14.7 9.4 0.03 14.7 9.4 4.5 3 1 1 4 4 4 0 Ring finger domain zf-C3HC4 PF00097.25 RJW61710.1 - 7.9 6.4 40.3 0.026 14.4 6.4 5.1 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Pkinase_Tyr PF07714.17 RJW61711.1 - 3e-13 49.7 0.0 3.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW61711.1 - 1.6e-08 34.3 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-C2H2 PF00096.26 RJW61712.1 - 7.4e-14 51.3 24.0 2e-05 24.8 4.1 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW61712.1 - 6.5e-12 45.3 18.3 4.8e-07 29.9 0.2 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW61712.1 - 2.9e-08 33.9 21.7 0.00046 20.8 2.6 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW61712.1 - 0.0016 18.4 4.9 0.32 11.1 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 RJW61712.1 - 0.52 11.0 8.9 1 10.0 0.1 3.7 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 RJW61712.1 - 1.6 8.7 9.1 1.9 8.5 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ADH_zinc_N_2 PF13602.6 RJW61713.1 - 6.8e-16 59.5 0.0 1e-14 55.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RJW61713.1 - 2e-07 31.0 0.0 4.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RJW61713.1 - 9.7e-05 22.2 0.0 0.00022 21.1 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 RJW61713.1 - 0.049 13.1 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DUF2617 PF10936.8 RJW61713.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2617 DEAD PF00270.29 RJW61714.1 - 1.1e-46 158.8 0.2 2.1e-46 157.9 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW61714.1 - 3.7e-24 85.2 0.0 7.2e-23 81.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RJW61714.1 - 1.6e-12 47.5 0.1 5e-12 45.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RJW61714.1 - 1.1e-06 28.7 0.0 2.8e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 RJW61714.1 - 7.3e-06 25.5 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_25 PF13481.6 RJW61714.1 - 0.021 14.4 0.0 0.43 10.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 RJW61714.1 - 0.061 13.6 0.2 0.93 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ribosomal_L5 PF00281.19 RJW61717.1 - 3.4e-22 78.5 0.1 2.3e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 tRNA_anti-like PF12869.7 RJW61717.1 - 0.14 11.7 0.2 0.25 10.9 0.0 1.6 1 1 1 2 2 2 0 tRNA_anti-like I-set PF07679.16 RJW61718.1 - 1.4e-16 60.3 0.0 2.5e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW61718.1 - 4.2e-13 49.7 0.0 8.6e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RJW61718.1 - 1.4e-11 44.4 0.0 4.3e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 RJW61718.1 - 2.7e-06 27.6 0.0 6.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 RJW61718.1 - 0.00029 20.8 0.1 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain EGF_2 PF07974.13 RJW61718.1 - 0.019 15.3 8.0 0.039 14.3 8.0 1.6 1 0 0 1 1 1 0 EGF-like domain V-set PF07686.17 RJW61718.1 - 0.028 14.6 0.0 0.18 12.0 0.0 2.3 1 1 0 1 1 1 0 Immunoglobulin V-set domain EGF PF00008.27 RJW61718.1 - 0.2 12.0 4.7 0.49 10.7 4.7 1.7 1 0 0 1 1 1 0 EGF-like domain NOT2_3_5 PF04153.18 RJW61719.1 - 6.8e-21 74.7 0.4 1.6e-20 73.6 0.4 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cadherin PF00028.17 RJW61720.1 - 1.8e-55 185.4 1.6 4e-11 43.2 0.0 9.5 9 1 0 9 9 9 8 Cadherin domain Cadherin_3 PF16184.5 RJW61720.1 - 0.12 12.4 8.6 6 6.9 0.4 5.1 5 1 0 5 5 5 0 Cadherin-like MULE PF10551.9 RJW61721.1 - 0.012 16.0 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 MULE transposase domain Tetraspanin PF00335.20 RJW61722.1 - 7.5e-38 130.5 11.6 9.9e-38 130.1 11.6 1.1 1 0 0 1 1 1 1 Tetraspanin family Exo_endo_phos PF03372.23 RJW61722.1 - 0.00018 21.1 0.3 0.00032 20.3 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TMCO5 PF14992.6 RJW61722.1 - 3 7.4 3.8 4.7 6.7 3.8 1.2 1 0 0 1 1 1 0 TMCO5 family DUF485 PF04341.12 RJW61722.1 - 8.8 6.4 8.7 39 4.3 4.2 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ABC_tran PF00005.27 RJW61723.1 - 2.4e-31 109.1 0.0 4e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RJW61723.1 - 9.1e-27 94.4 4.3 1.4e-26 93.8 4.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RJW61723.1 - 9.1e-06 25.3 0.0 4.2e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RJW61723.1 - 0.0041 17.5 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RJW61723.1 - 0.0054 17.0 0.0 0.048 13.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RJW61723.1 - 0.0087 15.8 0.1 0.048 13.4 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 RJW61723.1 - 0.028 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 RJW61723.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 RJW61723.1 - 0.096 12.5 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 RJW61723.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MULE PF10551.9 RJW61724.1 - 2.2e-08 34.4 0.0 5.8e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Nre_C PF04895.12 RJW61724.1 - 0.042 13.8 0.4 0.43 10.5 0.4 2.1 1 1 0 1 1 1 0 Archaeal Nre, C-terminal TMEM70 PF06979.12 RJW61725.1 - 0.27 11.6 1.3 5.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex Enkurin PF13864.6 RJW61726.1 - 3.4e-22 78.7 0.0 3.4e-22 78.7 0.0 2.2 3 0 0 3 3 3 1 Calmodulin-binding DUF1707 PF08044.11 RJW61726.1 - 2 8.5 6.3 0.17 12.0 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) MoCF_biosynth PF00994.24 RJW61727.1 - 3.6e-51 172.6 0.0 5.5e-26 90.9 0.0 2.2 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 RJW61727.1 - 4.7e-35 120.7 0.0 7.1e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 RJW61727.1 - 0.00089 19.4 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) zf-CCCH_4 PF18044.1 RJW61729.1 - 6.8e-15 54.5 24.3 2.2e-07 30.5 2.0 3.9 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH PF00642.24 RJW61729.1 - 1.2e-13 50.6 28.8 3.8e-05 23.5 4.2 4.0 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CHY PF05495.12 RJW61729.1 - 4e-10 40.0 9.4 4e-10 40.0 9.4 4.7 3 1 1 4 4 4 1 CHY zinc finger zf_CCCH_4 PF18345.1 RJW61729.1 - 6.9e-10 38.7 39.4 9e-06 25.6 5.7 4.1 4 0 0 4 4 4 3 Zinc finger domain Torus PF16131.5 RJW61729.1 - 2.3e-06 28.3 14.2 0.086 13.5 0.4 3.7 1 1 2 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 RJW61729.1 - 1.2e-05 25.5 26.2 0.0015 18.9 4.4 4.0 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RJW61729.1 - 0.045 14.0 8.3 0.31 11.3 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger containing family TPR_11 PF13414.6 RJW61731.1 - 0.00011 21.8 0.6 0.067 12.9 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 RJW61731.1 - 0.0042 17.8 1.9 2.1 9.4 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RJW61731.1 - 0.015 15.8 0.3 0.33 11.5 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RJW61731.1 - 0.033 14.3 10.2 3.5 8.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW61731.1 - 0.059 13.6 4.9 1.9 8.8 1.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 RJW61731.1 - 0.16 12.6 2.1 2.2 9.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RJW61731.1 - 0.33 11.4 1.9 1.1 9.9 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW61731.1 - 0.58 10.1 4.3 4.6 7.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4398 PF14346.6 RJW61731.1 - 2.1 9.0 7.0 5.3 7.7 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4398) Cadherin_3 PF16184.5 RJW61732.1 - 5.4e-25 87.6 0.6 5.6e-08 32.8 0.0 8.0 8 0 0 8 8 8 5 Cadherin-like G6PD_C PF02781.16 RJW61733.1 - 1.7e-107 359.0 0.0 2.5e-107 358.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 RJW61733.1 - 2.6e-57 194.3 0.0 4.2e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DHHC PF01529.20 RJW61734.1 - 3.4e-05 24.0 4.2 3.4e-05 24.0 4.2 3.5 3 1 0 3 3 3 2 DHHC palmitoyltransferase UPF0182 PF03699.13 RJW61734.1 - 0.28 9.2 0.0 0.48 8.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) RVT_1 PF00078.27 RJW61736.1 - 3e-46 157.7 0.6 1.1e-45 155.9 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW61736.1 - 5.5e-12 45.6 0.1 8.3e-11 41.8 0.0 3.2 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase MULE PF10551.9 RJW61737.1 - 8.5e-12 45.3 0.3 2e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain zf-C3H2C3 PF17122.5 RJW61737.1 - 0.0064 16.5 0.6 0.018 15.1 0.6 1.8 1 0 0 1 1 1 1 Zinc-finger Chibby PF14645.6 RJW61738.1 - 4.8e-45 152.7 0.1 5.8e-45 152.4 0.1 1.1 1 0 0 1 1 1 1 Chibby family bZIP_1 PF00170.21 RJW61738.1 - 0.053 13.6 2.3 0.17 12.0 1.5 2.1 3 0 0 3 3 3 0 bZIP transcription factor YabA PF06156.13 RJW61738.1 - 0.5 11.0 2.9 0.91 10.2 2.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA ThiF PF00899.21 RJW61739.1 - 2.2e-18 66.5 0.0 5.1e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 ThiF family RVT_1 PF00078.27 RJW61739.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAH PF02671.21 RJW61739.1 - 0.0098 16.0 0.0 1.4 9.1 0.0 3.7 4 1 0 4 4 4 1 Paired amphipathic helix repeat VHL_C PF17211.3 RJW61739.1 - 0.061 13.4 0.3 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 VHL box domain Lipase_3 PF01764.25 RJW61739.1 - 0.061 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) RRM_1 PF00076.22 RJW61740.1 - 7.2e-41 137.9 0.0 1.3e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW61740.1 - 1.1e-06 28.7 0.0 0.00079 19.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 RJW61740.1 - 1.8e-06 27.6 0.0 0.0024 17.5 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RJW61740.1 - 0.1 12.7 0.2 16 5.6 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 PHM7_cyt PF14703.6 RJW61740.1 - 0.12 12.5 0.1 3.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Mito_carr PF00153.27 RJW61742.1 - 3.8e-32 110.1 2.3 2.6e-12 46.5 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Proteasom_PSMB PF10508.9 RJW61744.1 - 4.3e-05 22.2 0.0 0.15 10.5 0.0 2.0 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit DUF433 PF04255.14 RJW61744.1 - 0.0028 17.5 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF433) CSTF_C PF14304.6 RJW61744.1 - 0.023 14.3 0.0 8.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal zinc-ribbons_6 PF07191.12 RJW61744.1 - 2.8 8.0 9.1 2.1 8.4 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbons ERO1 PF04137.15 RJW61746.1 - 3.6e-111 371.8 0.0 4.8e-111 371.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) zf-C2H2_4 PF13894.6 RJW61747.1 - 0.02 15.7 33.3 1.1 10.3 0.8 7.7 8 0 0 8 8 8 0 C2H2-type zinc finger DUF4187 PF13821.6 RJW61747.1 - 0.037 13.8 0.1 18 5.2 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) zf-met PF12874.7 RJW61747.1 - 0.2 12.1 17.8 4.4 7.8 0.4 5.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 RJW61747.1 - 0.32 11.5 3.8 13 6.4 0.0 3.8 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 RJW61747.1 - 1.5 9.2 18.5 1 9.7 0.1 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RJW61747.1 - 3.8 7.3 14.0 1.3 8.9 0.5 4.9 4 0 0 4 4 4 0 zinc-finger C2H2-type Ribosomal_S7 PF00177.21 RJW61748.1 - 1.9e-34 118.5 0.2 2.4e-34 118.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf_CCCH_4 PF18345.1 RJW61749.1 - 0.0032 17.5 5.3 0.0032 17.5 5.3 3.8 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH PF00642.24 RJW61749.1 - 0.0037 17.1 0.4 0.0037 17.1 0.4 3.9 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) BBP1_N PF15271.6 RJW61749.1 - 3.3 8.5 6.1 19 6.0 1.2 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein CNH PF00780.22 RJW61750.1 - 3.8e-35 121.8 0.0 5.6e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 RJW61750.1 - 7.9e-08 32.0 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61750.1 - 0.00096 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GTP_EFTU PF00009.27 RJW61751.1 - 1.6e-43 148.5 0.0 6.3e-43 146.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RJW61751.1 - 1.7e-27 95.9 0.3 5.5e-27 94.3 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RJW61751.1 - 0.00013 22.2 0.0 0.00037 20.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RJW61751.1 - 0.0025 17.9 0.0 0.011 15.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase LPD34 PF18852.1 RJW61751.1 - 0.14 11.7 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 Pkinase PF00069.25 RJW61752.1 - 2.3e-76 256.7 0.0 2.8e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61752.1 - 1.2e-33 116.5 0.0 1.6e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW61752.1 - 2.4e-06 27.1 0.0 9.6e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RJW61752.1 - 4.2e-05 23.6 0.1 0.0095 15.9 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW61752.1 - 0.00096 18.2 0.1 0.0027 16.7 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RJW61752.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RJW61752.1 - 0.0049 15.7 0.0 0.0083 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PUF PF00806.19 RJW61752.1 - 0.007 16.0 0.0 0.023 14.3 0.0 1.9 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat RIO1 PF01163.22 RJW61752.1 - 0.024 14.2 0.1 0.071 12.7 0.0 1.8 2 1 0 2 2 2 0 RIO1 family EF-hand_1 PF00036.32 RJW61753.1 - 9.4e-22 74.9 6.2 0.00029 20.2 0.0 5.5 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 RJW61753.1 - 8.6e-19 67.8 11.2 3.9e-07 30.4 0.3 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW61753.1 - 1.2e-18 65.6 6.3 0.00034 20.0 0.0 5.4 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 RJW61753.1 - 2.8e-17 61.1 7.8 2.6e-05 23.8 0.0 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 RJW61753.1 - 1.6e-12 47.1 10.0 0.028 14.3 0.0 5.4 5 0 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW61753.1 - 7e-06 26.3 12.2 0.0077 16.5 0.9 3.6 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 RJW61753.1 - 1.6 8.7 5.3 49 3.9 0.0 3.4 3 0 0 3 3 3 0 EF hand RNase_T PF00929.24 RJW61754.1 - 1.5e-12 48.4 0.0 2.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Methyltransf_32 PF13679.6 RJW61754.1 - 1.7e-10 41.1 0.0 2.9e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 RJW61754.1 - 0.00035 19.7 0.0 0.00078 18.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 RJW61754.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SNARE_assoc PF09335.11 RJW61756.1 - 1.6e-07 31.8 0.4 9.1e-07 29.4 0.2 2.2 2 1 0 2 2 2 1 SNARE associated Golgi protein GP41 PF00517.17 RJW61756.1 - 0.033 14.1 0.2 0.07 13.0 0.2 1.5 1 0 0 1 1 1 0 Retroviral envelope protein CD34_antigen PF06365.12 RJW61756.1 - 0.066 12.8 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family Hist_deacetyl PF00850.19 RJW61757.1 - 1.3e-75 254.8 0.1 1.8e-75 254.3 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF1676 PF07898.13 RJW61758.1 - 0.017 15.2 7.5 0.019 15.0 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DNA_pol_phi PF04931.13 RJW61760.1 - 0.036 12.2 9.5 0.034 12.3 9.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 RJW61760.1 - 0.07 12.9 16.5 0.089 12.5 16.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RJW61760.1 - 0.077 12.3 16.7 0.091 12.1 16.7 1.1 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 RJW61760.1 - 0.81 8.8 5.7 0.9 8.6 5.7 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RRN3 PF05327.11 RJW61760.1 - 7.4 5.0 8.0 7.1 5.0 8.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 fn3 PF00041.21 RJW61761.1 - 2e-31 108.1 7.9 7.8e-13 48.6 0.2 3.6 3 0 0 3 3 3 3 Fibronectin type III domain fn3_2 PF16893.5 RJW61761.1 - 1.1e-07 31.9 0.1 3.7e-06 27.0 0.0 3.2 3 0 0 3 3 3 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW61761.1 - 5.4e-06 26.9 2.3 0.71 10.5 0.1 4.0 3 1 0 3 3 3 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RJW61761.1 - 0.0012 19.2 0.3 5.8 7.3 0.0 4.0 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.6 RJW61761.1 - 0.0024 18.1 0.0 6.7 7.0 0.0 3.2 3 0 0 3 3 3 2 SusE outer membrane protein Arylsulfotran_N PF17425.2 RJW61761.1 - 0.0064 16.5 0.1 1.8 8.7 0.0 2.6 2 0 0 2 2 2 2 Arylsulfotransferase Ig-like domain Stathmin PF00836.19 RJW61762.1 - 0.0019 18.2 0.6 0.0019 18.2 0.6 2.1 3 0 0 3 3 3 1 Stathmin family Acylphosphatase PF00708.18 RJW61763.1 - 1.3e-07 31.9 0.5 6.5e-07 29.7 0.5 1.8 1 1 0 1 1 1 1 Acylphosphatase UQ_con PF00179.26 RJW61764.1 - 3.3e-29 101.3 0.1 3.6e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Adap_comp_sub PF00928.21 RJW61768.1 - 1.6e-48 165.4 0.0 2.3e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family SRP-alpha_N PF04086.13 RJW61769.1 - 0.068 13.1 4.7 0.096 12.6 4.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2981 PF11200.8 RJW61769.1 - 0.13 11.9 1.4 0.29 10.9 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) DUF4662 PF15578.6 RJW61769.1 - 0.25 11.1 4.4 0.38 10.5 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) GMP_PDE_delta PF05351.11 RJW61770.1 - 2.6e-08 34.1 0.0 2.9e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit WD40 PF00400.32 RJW61771.1 - 1.3e-20 73.3 3.8 8.2e-05 23.3 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW61771.1 - 3.1e-16 59.4 0.0 0.00015 22.0 0.0 5.6 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain TFIID_30kDa PF03540.13 RJW61772.1 - 3.5e-18 65.3 0.0 5.8e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 RJW61772.1 - 0.042 13.6 0.1 4.9 6.8 0.1 2.1 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family MIF4G PF02854.19 RJW61773.1 - 1.1e-09 38.3 0.4 2.2e-09 37.3 0.4 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 RJW61773.1 - 4.2e-08 33.2 0.0 3.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 MA3 domain eIF_4EBP PF05456.11 RJW61773.1 - 0.0037 17.2 0.0 0.0037 17.2 0.0 2.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PLAC8 PF04749.17 RJW61774.1 - 5.4e-12 46.6 14.3 1.3e-11 45.4 14.3 1.6 1 1 0 1 1 1 1 PLAC8 family Band_7 PF01145.25 RJW61775.1 - 1.4e-29 103.4 1.3 2.2e-29 102.7 1.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 RJW61775.1 - 0.0049 16.6 0.1 0.0076 16.0 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 RJW61775.1 - 0.099 13.0 2.6 0.37 11.2 0.6 2.8 2 1 1 3 3 3 0 Phage protein Gp68 PID PF00640.23 RJW61776.1 - 1.1e-15 57.9 0.3 3.9e-15 56.1 0.2 2.0 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) E1_DerP2_DerF2 PF02221.15 RJW61777.1 - 1e-14 55.1 0.2 1.2e-14 54.9 0.2 1.0 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 RJW61780.1 - 1.5e-15 57.8 0.0 1.8e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 ML domain Calreticulin PF00262.18 RJW61783.1 - 0.067 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Calreticulin family DUF4806 PF16064.5 RJW61784.1 - 5.6e-12 45.8 0.1 1.5e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4806) DUF2039 PF10217.9 RJW61785.1 - 1.2e-31 108.8 9.0 1.7e-31 108.4 9.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Zn-ribbon_8 PF09723.10 RJW61785.1 - 0.011 15.9 1.5 0.63 10.2 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 RJW61785.1 - 0.056 13.4 6.9 0.12 12.3 6.9 1.5 1 1 0 1 1 1 0 zinc-ribbons DUF2797 PF10977.8 RJW61785.1 - 0.39 10.6 6.1 0.16 11.8 3.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2797) FYVE_2 PF02318.16 RJW61785.1 - 1.6 9.0 10.7 0.71 10.1 7.6 1.9 1 1 2 3 3 3 0 FYVE-type zinc finger DZR PF12773.7 RJW61785.1 - 2.1 8.5 9.8 51 4.0 9.9 2.6 1 1 1 2 2 2 0 Double zinc ribbon Cript PF10235.9 RJW61785.1 - 9.7 6.8 13.7 82 3.9 13.7 2.4 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Sec1 PF00995.23 RJW61787.1 - 2.9e-45 155.6 0.0 1.8e-44 153.0 0.0 1.9 1 1 0 1 1 1 1 Sec1 family CUB PF00431.20 RJW61793.1 - 7.5e-38 129.3 0.0 3e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.20 RJW61793.1 - 0.0035 17.1 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 2 CUB-like domain ALAD PF00490.21 RJW61795.1 - 9.7e-109 363.4 0.0 1.1e-108 363.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase E1_DerP2_DerF2 PF02221.15 RJW61796.1 - 5.4e-06 26.9 0.0 7.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 RJW61797.1 - 1.4e-07 32.0 0.0 1.6e-07 31.9 0.0 1.0 1 0 0 1 1 1 1 ML domain zf-C2H2 PF00096.26 RJW61800.1 - 7.2e-17 60.8 22.8 0.0005 20.4 0.4 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW61800.1 - 2.1e-13 50.0 21.3 8.1e-06 26.0 0.9 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW61800.1 - 3.5e-11 43.0 20.5 0.0095 16.7 1.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RJW61800.1 - 0.0083 16.4 6.9 0.44 10.9 7.0 2.5 1 1 0 1 1 1 1 C2H2-type zinc ribbon Raffinose_syn PF05691.12 RJW61800.1 - 0.062 11.1 0.0 0.093 10.5 0.0 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 zf-C2H2_11 PF16622.5 RJW61800.1 - 0.13 12.0 3.4 5.4 6.9 0.4 3.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 RJW61800.1 - 0.18 12.0 5.5 21 5.2 0.1 3.1 2 1 0 3 3 3 0 Aberrant zinc-finger IBR PF01485.21 RJW61800.1 - 0.53 10.6 6.1 0.39 11.0 3.5 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-CGNR PF11706.8 RJW61800.1 - 1 9.3 3.4 8.8 6.3 0.5 3.0 2 1 0 2 2 2 0 CGNR zinc finger zf-C2H2_jaz PF12171.8 RJW61800.1 - 1.7 9.0 7.5 5.9 7.3 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.12 RJW61800.1 - 3.4 8.5 9.2 7 7.5 2.1 3.0 1 1 3 4 4 4 0 CHORD zf-TRAF PF02176.18 RJW61800.1 - 4.9 7.9 11.5 18 6.1 3.8 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger NUDIX PF00293.28 RJW61801.1 - 1.5e-12 47.7 0.0 2.1e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_M60 PF13402.6 RJW61802.1 - 8.2e-17 61.6 0.9 1.4e-16 60.8 0.9 1.4 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 RJW61802.1 - 3.7e-07 30.0 0.0 9.2e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Reprolysin_3 PF13582.6 RJW61802.1 - 0.13 12.7 0.1 0.31 11.6 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like VHL PF01847.16 RJW61804.1 - 0.047 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 VHL beta domain EamA PF00892.20 RJW61808.1 - 2.4 8.3 31.4 0.16 12.2 5.9 2.9 3 0 0 3 3 3 0 EamA-like transporter family zf-met PF12874.7 RJW61810.1 - 2.9e-05 24.3 29.7 0.14 12.6 0.3 7.4 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 RJW61810.1 - 0.01 16.2 2.0 0.01 16.2 2.0 12.7 13 1 0 13 13 13 0 Zinc finger, C2H2 type Phage_GPD PF05954.11 RJW61810.1 - 0.098 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) zf-H2C2_2 PF13465.6 RJW61810.1 - 1.6 9.3 21.2 0.93 10.0 0.1 7.6 6 0 0 6 6 6 0 Zinc-finger double domain Peptidase_M60 PF13402.6 RJW61811.1 - 5.6e-17 62.1 4.4 6.6e-17 61.9 4.4 1.1 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like Reprolysin_3 PF13582.6 RJW61811.1 - 0.017 15.6 0.1 0.03 14.8 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Myotub-related PF06602.14 RJW61812.1 - 1.4e-35 122.9 0.0 1e-34 120.0 0.0 2.0 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain BUD22 PF09073.10 RJW61815.1 - 1.8e-05 24.3 42.0 2.6e-05 23.8 42.0 1.2 1 0 0 1 1 1 1 BUD22 Kin17_mid PF10357.9 RJW61815.1 - 5.7 6.9 5.8 0.57 10.1 0.6 1.9 1 1 1 2 2 2 0 Domain of Kin17 curved DNA-binding protein LRR_8 PF13855.6 RJW61817.1 - 6.3e-11 41.9 4.3 8.5e-08 31.9 0.1 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRRNT PF01462.18 RJW61817.1 - 7.1e-05 22.4 5.3 7.1e-05 22.4 5.3 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 RJW61817.1 - 0.0022 18.3 3.2 2.7 8.9 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.7 RJW61817.1 - 0.013 15.9 6.7 0.36 11.3 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RJW61817.1 - 0.019 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) I-set PF07679.16 RJW61817.1 - 0.18 11.9 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain cNMP_binding PF00027.29 RJW61818.1 - 3e-42 142.6 0.1 2.5e-21 75.5 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 RJW61818.1 - 1.1e-09 37.7 0.0 3.2e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit CP2 PF04516.15 RJW61819.1 - 1.1e-44 152.4 0.0 1.9e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 RJW61819.1 - 1.8e-12 46.9 0.0 4.3e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RJW61819.1 - 0.013 16.0 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 RJW61819.1 - 0.035 14.1 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain RcsC PF09456.10 RJW61824.1 - 0.057 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) Cadherin PF00028.17 RJW61825.1 - 7.6e-28 96.8 1.6 9e-07 29.3 0.0 6.2 6 1 0 6 6 6 4 Cadherin domain Cadherin_2 PF08266.12 RJW61825.1 - 0.0024 17.7 0.0 2.9 7.8 0.0 2.9 2 0 0 2 2 2 2 Cadherin-like DUF4981 PF16353.5 RJW61825.1 - 0.12 12.8 0.0 0.62 10.6 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function(DUF4981) CENP-B_dimeris PF09026.10 RJW61828.1 - 6.9e-05 23.2 4.6 8e-05 23.0 4.6 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.6 RJW61828.1 - 0.0071 16.7 8.0 0.012 16.0 8.0 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 RJW61828.1 - 0.0089 14.2 2.7 0.0083 14.3 2.7 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 RJW61828.1 - 0.081 11.1 0.4 0.07 11.3 0.4 1.1 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.13 RJW61828.1 - 0.11 11.1 1.0 0.11 11.1 1.0 1.1 1 0 0 1 1 1 0 Utp14 protein GCIP PF13324.6 RJW61828.1 - 0.45 10.1 2.4 0.45 10.1 2.4 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRM_1 PF00076.22 RJW61829.1 - 3.9e-17 61.8 0.0 5.9e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 RJW61829.1 - 5.1e-05 23.2 5.7 8.2e-05 22.5 5.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RJW61829.1 - 0.00039 20.3 0.1 0.00062 19.7 0.1 1.3 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 RJW61829.1 - 0.0015 18.1 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_5 PF14787.6 RJW61829.1 - 0.0049 16.6 1.8 0.0079 15.9 1.8 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RRM_7 PF16367.5 RJW61829.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 RJW61829.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif PDZ PF00595.24 RJW61830.1 - 4.5e-21 75.0 1.7 1.5e-10 41.2 0.1 3.1 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 RJW61830.1 - 2.4e-15 56.1 4.1 3.5e-08 33.2 0.7 2.9 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RJW61830.1 - 6.9e-09 35.9 0.9 0.00024 21.3 0.2 3.2 2 1 1 3 3 3 2 PDZ domain Par3_HAL_N_term PF12053.8 RJW61830.1 - 3.5e-07 30.3 0.7 7.1e-07 29.4 0.7 1.5 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins NAPRTase_C PF17956.1 RJW61831.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain DcpS_C PF11969.8 RJW61834.1 - 1.5e-16 60.9 0.0 2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 RJW61834.1 - 4.6e-08 33.7 0.0 6.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 HIT domain RL10P_insert PF17777.1 RJW61836.1 - 2.1e-22 78.9 0.0 4.9e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 RJW61836.1 - 8e-14 51.6 0.2 1.3e-13 50.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Transglut_core PF01841.19 RJW61836.1 - 0.023 15.2 0.0 0.061 13.8 0.0 1.7 2 0 0 2 2 2 0 Transglutaminase-like superfamily DNA_primase_lrg PF04104.14 RJW61838.1 - 4.2e-79 265.7 0.0 6.8e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Herpes_gI PF01688.17 RJW61842.1 - 0.052 13.5 0.5 0.11 12.4 0.5 1.5 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein I COQ9 PF08511.11 RJW61843.1 - 3e-27 94.2 0.1 6.8e-27 93.1 0.1 1.6 1 0 0 1 1 1 1 COQ9 Cep57_CLD PF14073.6 RJW61843.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 LMF1 PF06762.14 RJW61844.1 - 1e-50 173.2 3.9 1.3e-50 172.8 3.9 1.1 1 0 0 1 1 1 1 Lipase maturation factor E1-E2_ATPase PF00122.20 RJW61845.1 - 0.05 13.1 0.0 0.05 13.1 0.0 2.2 3 0 0 3 3 3 0 E1-E2 ATPase Nop14 PF04147.12 RJW61849.1 - 1.3e-25 89.8 30.6 7.5e-18 64.2 9.7 2.9 2 1 0 2 2 2 2 Nop14-like family P-mevalo_kinase PF04275.14 RJW61849.1 - 0.062 13.3 0.2 0.3 11.1 0.2 2.1 2 0 0 2 2 2 0 Phosphomevalonate kinase NRIP1_repr_3 PF15689.5 RJW61849.1 - 0.076 13.3 0.1 0.32 11.3 0.0 2.1 1 1 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 3 SH3_1 PF00018.28 RJW61850.1 - 1.4e-06 27.8 0.0 2.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 RJW61850.1 - 0.019 15.2 1.6 0.093 13.0 0.0 2.8 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain AKNA PF12443.8 RJW61850.1 - 0.1 13.3 0.4 0.1 13.3 0.4 3.2 3 1 1 4 4 4 0 AT-hook-containing transcription factor Med9 PF07544.13 RJW61850.1 - 0.29 11.3 2.4 0.34 11.0 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_2 PF07716.15 RJW61850.1 - 2.3 8.4 4.9 26 5.0 0.1 3.1 3 0 0 3 3 3 0 Basic region leucine zipper FAM184 PF15665.5 RJW61850.1 - 6.6 6.5 15.9 0.92 9.2 4.6 3.2 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B HMG_box PF00505.19 RJW61851.1 - 1.5e-14 54.2 2.4 1.5e-14 54.2 2.4 2.2 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW61851.1 - 3.5e-05 24.3 2.0 3.5e-05 24.3 2.0 2.6 2 0 0 2 2 2 1 HMG-box domain Bud13 PF09736.9 RJW61851.1 - 5.2 7.5 34.7 7.2 7.0 19.2 3.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Ras PF00071.22 RJW61852.1 - 1.3e-44 151.7 0.0 1.5e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW61852.1 - 1.8e-25 89.5 0.0 2.6e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW61852.1 - 2.4e-06 27.1 0.0 4.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW61852.1 - 0.025 14.6 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RJW61852.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RJW61852.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ion_trans PF00520.31 RJW61853.1 - 5e-30 104.5 10.2 9.6e-30 103.6 10.2 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 RJW61853.1 - 1.9e-10 40.0 2.7 3.1e-10 39.3 2.7 1.3 1 0 0 1 1 1 1 Polycystin cation channel DUF1345 PF07077.11 RJW61853.1 - 0.002 17.9 1.5 0.14 11.8 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1345) Katanin_con80 PF13925.6 RJW61854.1 - 2.9e-07 30.7 0.0 4.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin SNF PF00209.18 RJW61855.1 - 7.7e-17 61.2 1.3 9e-17 61.0 1.3 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DELLA PF12041.8 RJW61855.1 - 0.13 12.1 0.1 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal A_deaminase PF00962.22 RJW61856.1 - 6.1e-14 52.1 0.0 9.1e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase rve PF00665.26 RJW61857.1 - 0.00013 22.1 0.0 0.00028 21.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Na_Ca_ex_C PF16494.5 RJW61857.1 - 0.016 15.6 0.1 0.03 14.8 0.1 1.4 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain RhoGEF PF00621.20 RJW61858.1 - 1e-27 97.6 1.3 1.7e-27 96.9 1.3 1.3 1 0 0 1 1 1 1 RhoGEF domain Tektin PF03148.14 RJW61859.1 - 1.7e-136 455.0 28.0 2.4e-136 454.5 28.0 1.2 1 0 0 1 1 1 1 Tektin family RVT_1 PF00078.27 RJW61859.1 - 5.7e-46 156.8 2.0 1.1e-45 155.8 0.0 2.4 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW61859.1 - 1e-11 44.7 1.3 8.3e-11 41.8 0.0 3.3 5 0 0 5 5 5 1 Endonuclease-reverse transcriptase PHD PF00628.29 RJW61859.1 - 0.0012 18.7 6.7 0.0029 17.5 6.7 1.6 1 0 0 1 1 1 1 PHD-finger LMBR1 PF04791.16 RJW61859.1 - 0.72 8.7 3.9 1.3 7.9 3.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1043 PF06295.12 RJW61859.1 - 1.6 8.7 4.5 0.92 9.5 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF1640 PF07798.11 RJW61859.1 - 7.9 6.5 12.7 17 5.4 0.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Tubulin PF00091.25 RJW61861.1 - 4e-68 229.5 0.0 5.5e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW61861.1 - 4e-52 175.7 0.0 6.3e-52 175.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW61861.1 - 0.0019 17.9 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain VASP_tetra PF08776.11 RJW61862.1 - 0.0014 18.2 0.5 1.8 8.2 0.0 3.0 3 0 0 3 3 3 2 VASP tetramerisation domain Utp13 PF08625.11 RJW61863.1 - 0.0061 16.5 4.3 1.2 9.0 0.3 2.4 2 0 0 2 2 2 2 Utp13 specific WD40 associated domain CDRT4 PF15213.6 RJW61863.1 - 0.014 16.0 1.1 0.038 14.6 1.1 1.7 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein GTP_EFTU PF00009.27 RJW61864.1 - 1.7e-50 171.3 0.3 3.3e-50 170.3 0.3 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RJW61864.1 - 8.4e-15 54.9 1.0 1.6e-14 54.1 1.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 RJW61864.1 - 9.3e-13 48.5 0.0 1.9e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 RJW61864.1 - 0.0029 17.7 0.1 0.018 15.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RVT_1 PF00078.27 RJW61864.1 - 0.015 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CUE PF02845.16 RJW61866.1 - 0.022 14.4 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 CUE domain HBS1_N PF08938.10 RJW61866.1 - 0.027 14.8 0.1 0.065 13.5 0.1 1.6 1 0 0 1 1 1 0 HBS1 N-terminus MMR_HSR1 PF01926.23 RJW61867.1 - 1.1e-13 51.3 0.0 2.6e-12 46.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RJW61867.1 - 0.00071 19.1 0.0 0.0021 17.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RJW61867.1 - 0.0015 18.4 0.0 0.082 12.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Enterotoxin_b PF01376.18 RJW61867.1 - 0.082 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain Dynamin_N PF00350.23 RJW61867.1 - 0.13 12.3 0.2 2.4 8.2 0.1 2.7 2 1 1 3 3 3 0 Dynamin family zf-C2H2 PF00096.26 RJW61868.1 - 1.4e-16 59.9 28.9 2.5e-05 24.5 0.8 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW61868.1 - 3.1e-13 49.3 27.2 0.0029 18.3 1.6 5.5 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW61868.1 - 3.2e-10 40.0 26.2 2.9e-06 27.4 0.4 5.9 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW61868.1 - 3.8e-06 26.7 23.3 0.0072 16.3 0.4 5.7 6 0 0 6 6 5 3 C2H2-type zinc finger zf-met PF12874.7 RJW61868.1 - 0.00022 21.5 20.4 0.0082 16.5 0.5 4.8 5 0 0 5 5 4 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 RJW61868.1 - 0.00031 20.6 16.8 0.35 10.8 0.3 4.9 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 RJW61868.1 - 0.0017 19.1 13.8 0.026 15.2 12.3 3.6 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 RJW61868.1 - 0.0029 17.3 26.9 0.022 14.5 1.4 4.6 4 0 0 4 4 4 2 zinc-finger C2H2-type zf_UBZ PF18439.1 RJW61868.1 - 0.0051 16.4 10.4 0.92 9.2 0.0 4.5 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 RJW61868.1 - 0.024 14.9 13.4 0.097 13.0 1.1 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RJW61868.1 - 0.033 14.5 4.6 0.033 14.5 4.6 3.3 2 1 2 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 RJW61868.1 - 0.16 11.8 4.1 0.11 12.4 1.1 2.2 1 1 1 2 2 2 0 GAGA factor DUF1677 PF07911.13 RJW61868.1 - 0.16 12.4 0.4 0.16 12.4 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1677) C1_2 PF03107.16 RJW61868.1 - 0.17 12.2 19.8 4.3 7.7 0.2 5.2 2 1 3 5 5 5 0 C1 domain ADK_lid PF05191.14 RJW61868.1 - 0.19 11.8 11.2 0.2 11.7 0.8 3.5 3 0 0 3 3 3 0 Adenylate kinase, active site lid Sgf11 PF08209.11 RJW61868.1 - 0.4 10.3 13.6 4.7 6.9 0.2 4.5 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) Actin_micro PF17003.5 RJW61868.1 - 0.4 9.8 9.2 5.2 6.2 3.4 2.6 1 1 0 2 2 2 0 Putative actin-like family zf_ZIC PF18366.1 RJW61868.1 - 0.91 9.7 4.1 44 4.3 0.5 3.4 2 1 1 3 3 3 0 Zic proteins zinc finger domain XPA_N PF01286.18 RJW61868.1 - 0.94 9.6 6.0 34 4.6 0.1 4.0 4 0 0 4 4 4 0 XPA protein N-terminal zf-3CxxC PF13695.6 RJW61868.1 - 1.1 9.8 12.9 0.29 11.6 3.3 3.3 1 1 3 4 4 4 0 Zinc-binding domain zf-CCHC_2 PF13696.6 RJW61868.1 - 1.1 9.1 17.3 3.9 7.4 1.2 4.0 4 0 0 4 4 4 0 Zinc knuckle CpXC PF14353.6 RJW61868.1 - 1.6 8.8 11.2 5.5 7.1 0.2 4.1 1 1 3 4 4 4 0 CpXC protein zf_C2H2_ZHX PF18387.1 RJW61868.1 - 3.4 7.4 7.0 1.4 8.6 0.4 2.8 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn-ribbon_8 PF09723.10 RJW61868.1 - 3.9 7.7 15.0 7 6.9 2.1 4.5 2 1 2 4 4 4 0 Zinc ribbon domain FYVE PF01363.21 RJW61868.1 - 4.2 7.6 18.6 1e+02 3.1 1.6 3.5 2 1 1 3 3 3 0 FYVE zinc finger zf-C2HE PF16278.5 RJW61868.1 - 5.9 7.4 8.7 7.8 7.0 0.9 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Desulfoferrod_N PF06397.12 RJW61868.1 - 7.1 6.4 13.5 2.3 7.9 0.2 3.7 4 0 0 4 4 3 0 Desulfoferrodoxin, N-terminal domain zf-BED PF02892.15 RJW61868.1 - 7.5 6.7 26.4 1.2 9.3 2.9 4.3 3 2 2 5 5 4 0 BED zinc finger zf-C2H2 PF00096.26 RJW61872.1 - 1.2e-17 63.2 47.8 9e-05 22.7 0.6 8.7 7 1 1 8 8 8 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW61872.1 - 1.9e-15 56.5 42.7 0.00038 20.8 1.0 8.7 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW61872.1 - 8.6e-11 41.7 48.7 0.0022 18.7 0.6 8.3 7 1 1 8 8 8 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RJW61872.1 - 0.0011 18.6 28.2 0.021 14.5 0.9 5.8 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RJW61872.1 - 0.084 13.2 0.3 0.084 13.2 0.3 7.6 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 RJW61872.1 - 0.12 13.1 16.7 0.98 10.1 3.2 4.3 2 2 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 RJW61872.1 - 0.17 12.2 23.8 0.28 11.5 3.1 5.1 2 2 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 RJW61872.1 - 5.1 7.5 24.9 0.17 12.2 3.5 4.3 2 2 2 4 4 4 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 RJW61872.1 - 6.5 6.5 14.2 2.4 7.9 0.3 4.4 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain Sulfotransfer_3 PF13469.6 RJW61873.1 - 4.3e-35 122.1 0.2 9.6e-35 120.9 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RJW61873.1 - 7.1e-08 32.2 0.1 1.4e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Peptidase_S48 PF03574.15 RJW61874.1 - 0.097 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S48 GerD PF17898.1 RJW61874.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Spore germination GerD central core domain zf-RING_9 PF13901.6 RJW61875.1 - 1.4e-56 191.8 12.9 2.4e-56 191.0 12.9 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Tubulin PF00091.25 RJW61876.1 - 5.6e-63 212.7 0.0 9.6e-63 211.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW61876.1 - 1.5e-50 170.5 0.0 2.9e-50 169.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW61876.1 - 0.18 11.4 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain DUF1759 PF03564.15 RJW61877.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) NPR3 PF03666.13 RJW61878.1 - 2.1e-18 66.4 9.3 4.1e-17 62.1 2.7 3.0 4 1 0 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 RVT_1 PF00078.27 RJW61878.1 - 5.4e-10 39.2 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Alba PF01918.21 RJW61878.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Alba Mob1_phocein PF03637.17 RJW61879.1 - 2.4e-75 252.2 0.2 3.2e-75 251.8 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family CDC45 PF02724.14 RJW61880.1 - 0.097 10.9 7.0 0.12 10.7 7.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 RJW61880.1 - 0.33 9.0 2.3 0.37 8.8 2.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.9 RJW61880.1 - 0.42 9.7 18.2 0.51 9.4 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 RJW61880.1 - 0.44 9.8 16.9 0.65 9.3 16.9 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RJW61880.1 - 1.8 6.6 15.3 2.2 6.3 15.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 RJW61880.1 - 1.9 7.7 5.1 2.1 7.6 5.1 1.0 1 0 0 1 1 1 0 BUD22 SGT1 PF07093.11 RJW61880.1 - 2.1 6.7 3.8 2.4 6.5 3.8 1.1 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.12 RJW61880.1 - 2.1 6.4 7.5 2.2 6.4 7.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RJW61880.1 - 2.1 7.7 8.6 2.4 7.5 8.6 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 RJW61880.1 - 4.5 5.7 6.9 5 5.6 6.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.11 RJW61880.1 - 10 6.2 7.1 14 5.7 7.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal ESR1_C PF12743.7 RJW61881.1 - 3.6 7.5 7.9 0.42 10.4 0.3 2.5 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal DUF4200 PF13863.6 RJW61882.1 - 7.8e-15 55.3 17.1 7.8e-15 55.3 17.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) DUF4867 PF16161.5 RJW61882.1 - 0.035 13.6 0.5 1.1 8.6 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4867) FUSC PF04632.12 RJW61882.1 - 1.3 7.5 5.5 1.7 7.1 5.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 RJW61882.1 - 1.4 8.9 5.1 3 7.9 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 RJW61882.1 - 2.9 7.9 29.9 0.76 9.8 10.8 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DASH_Dad3 PF08656.10 RJW61882.1 - 4.2 7.5 13.3 0.28 11.3 2.5 3.7 2 2 0 2 2 2 0 DASH complex subunit Dad3 zf-C2H2 PF00096.26 RJW61883.1 - 5.4e-14 51.8 31.4 3.6e-06 27.1 1.7 4.6 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW61883.1 - 4.2e-12 45.8 31.3 0.00021 21.9 1.9 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW61883.1 - 1.4e-10 41.1 29.8 0.00078 19.8 0.5 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-met PF12874.7 RJW61883.1 - 3e-05 24.2 25.7 0.095 13.1 0.1 4.9 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RJW61883.1 - 0.0015 18.2 1.9 0.0015 18.2 1.9 3.9 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-MYST PF17772.1 RJW61883.1 - 0.0056 16.3 16.9 0.051 13.2 0.3 3.8 2 2 2 4 4 4 2 MYST family zinc finger domain DUF2256 PF10013.9 RJW61883.1 - 0.01 15.9 11.6 4.4 7.5 0.5 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 RJW61883.1 - 0.012 15.4 1.6 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 GAGA factor DUF629 PF04780.12 RJW61883.1 - 0.021 13.4 1.2 0.021 13.4 1.2 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF629) DUF3268 PF11672.8 RJW61883.1 - 0.024 14.9 2.5 0.024 14.9 2.5 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain PriA_CRR PF18319.1 RJW61883.1 - 0.048 13.7 1.2 0.048 13.7 1.2 3.4 5 0 0 5 5 4 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2H2_6 PF13912.6 RJW61883.1 - 0.058 13.4 30.2 0.49 10.5 0.5 5.0 5 1 0 5 5 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RJW61883.1 - 0.071 13.5 22.9 1.8 9.0 0.1 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 RJW61883.1 - 0.074 13.2 19.7 5.5 7.2 12.9 3.1 1 1 2 3 3 3 0 FYVE zinc finger zf-C2HC_2 PF13913.6 RJW61883.1 - 0.24 11.3 16.0 4.4 7.3 0.3 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 RJW61883.1 - 0.33 11.7 14.8 1.7 9.5 4.9 2.4 1 1 2 3 3 3 0 zinc-ribbon family BolA PF01722.18 RJW61883.1 - 0.52 10.6 5.6 17 5.8 0.1 2.8 1 1 1 2 2 2 0 BolA-like protein Cript PF10235.9 RJW61883.1 - 0.87 10.2 14.4 11 6.7 0.0 4.0 2 2 1 3 3 3 0 Microtubule-associated protein CRIPT XPA_N PF01286.18 RJW61883.1 - 0.92 9.6 0.0 0.92 9.6 0.0 4.1 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_jaz PF12171.8 RJW61883.1 - 2 8.8 0.0 2 8.8 0.0 4.6 5 1 0 5 5 4 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 RJW61883.1 - 3 7.8 21.1 0.61 10.1 5.3 3.5 1 1 3 4 4 4 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 RJW61883.1 - 4.4 7.0 16.5 10 5.8 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF2072 PF09845.9 RJW61883.1 - 9.2 6.5 12.1 35 4.7 12.0 1.9 1 1 1 2 2 2 0 Zn-ribbon containing protein JmjC PF02373.22 RJW61884.1 - 3.1e-21 75.9 1.7 1.7e-20 73.6 1.7 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 RJW61884.1 - 1.3e-10 41.4 0.7 3.7e-10 39.9 0.7 1.7 1 1 0 1 1 1 1 Cupin-like domain DUF1618 PF07762.14 RJW61884.1 - 0.0086 16.7 0.2 0.02 15.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1618) Strabismus PF06638.11 RJW61885.1 - 8.9e-111 371.0 0.0 3.4e-93 313.0 0.0 3.8 2 1 1 3 3 3 3 Strabismus protein Pkinase PF00069.25 RJW61886.1 - 9.5e-56 189.1 0.0 1.2e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61886.1 - 5.7e-23 81.5 0.0 8.8e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW61886.1 - 0.00075 19.5 0.2 0.0046 16.9 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RJW61886.1 - 0.0024 17.2 0.2 0.0039 16.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RJW61886.1 - 0.027 14.1 0.1 0.053 13.1 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 RJW61886.1 - 0.038 13.6 0.9 0.11 12.0 0.8 1.8 2 1 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 RJW61886.1 - 0.1 11.9 0.2 6.5 6.0 0.0 2.1 1 1 0 2 2 2 0 Kinase-like Pkinase PF00069.25 RJW61887.1 - 5.4e-49 166.9 0.0 6.3e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61887.1 - 4.2e-33 114.7 0.0 5.4e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW61887.1 - 3.6e-05 23.2 0.0 5.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 RJW61887.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RJW61887.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GvpH PF05455.11 RJW61888.1 - 0.00068 19.8 42.4 0.6 10.2 3.0 5.1 1 1 4 5 5 5 4 GvpH F_actin_bund_C PF18060.1 RJW61888.1 - 0.00095 19.2 20.1 3.4 7.9 1.0 4.5 1 1 3 4 4 4 4 F actin bundling C terminal TFIIF_beta PF02270.15 RJW61888.1 - 0.15 12.2 2.8 2.3e+02 2.0 0.0 4.2 4 0 0 4 4 4 0 TFIIF, beta subunit HTH domain DUF2401 PF10287.9 RJW61888.1 - 1.4 8.4 21.8 43 3.6 0.0 5.9 6 0 0 6 6 6 0 Putative TOS1-like glycosyl hydrolase (DUF2401) BTB PF00651.31 RJW61889.1 - 2.7e-16 59.8 0.0 5.1e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain GpcrRhopsn4 PF10192.9 RJW61891.1 - 0.0064 15.9 0.1 0.0064 15.9 0.1 3.3 3 1 0 3 3 3 2 Rhodopsin-like GPCR transmembrane domain zf-H2C2_2 PF13465.6 RJW61892.1 - 2.2e-14 53.1 28.0 1.3e-05 25.4 0.1 5.6 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW61892.1 - 1.5e-12 47.2 27.9 0.00077 20.1 0.6 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW61892.1 - 1.2e-11 44.3 31.5 0.00017 21.8 0.5 4.7 4 1 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 RJW61892.1 - 2.4e-06 28.2 16.4 0.039 14.6 0.3 4.0 1 1 3 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 RJW61892.1 - 0.0025 18.2 14.3 0.87 10.1 0.8 4.7 4 1 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RJW61892.1 - 0.0075 16.0 2.5 0.0075 16.0 2.5 3.8 4 0 0 4 4 4 2 zinc-finger C2H2-type DUF3268 PF11672.8 RJW61892.1 - 0.0077 16.6 5.0 0.082 13.2 0.6 2.2 2 0 0 2 2 2 1 zinc-finger-containing domain zf-C2H2_6 PF13912.6 RJW61892.1 - 0.013 15.5 25.9 0.26 11.4 0.1 4.6 4 1 0 4 4 4 0 C2H2-type zinc finger CDC50 PF03381.15 RJW61892.1 - 0.08 12.4 1.5 0.085 12.4 0.6 1.4 1 1 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family zf-C2H2_jaz PF12171.8 RJW61892.1 - 0.14 12.5 12.9 3.7 8.0 0.8 4.8 4 2 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.21 RJW61892.1 - 0.34 11.1 25.2 8.1 6.7 7.0 3.8 1 1 1 2 2 2 0 FYVE zinc finger zf-Sec23_Sec24 PF04810.15 RJW61892.1 - 0.63 10.1 11.1 2.4 8.3 0.2 4.2 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger Zn_ribbon_SprT PF17283.2 RJW61892.1 - 0.91 9.5 15.4 1.7 8.6 11.7 3.1 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Ribosomal_S14 PF00253.21 RJW61892.1 - 1.2 9.0 8.0 0.68 9.8 0.6 2.9 2 1 1 3 3 3 0 Ribosomal protein S14p/S29e Zn-ribbon_8 PF09723.10 RJW61892.1 - 3.1 8.0 16.6 18 5.5 0.1 4.1 2 1 1 3 3 3 0 Zinc ribbon domain zf-MYST PF17772.1 RJW61892.1 - 9.6 5.9 11.2 2.1 8.0 2.0 3.4 2 2 2 4 4 4 0 MYST family zinc finger domain DUF1158 PF06643.11 RJW61893.1 - 0.022 15.3 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) Ras PF00071.22 RJW61895.1 - 5.5e-49 165.9 0.0 6.3e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW61895.1 - 3.9e-18 65.8 0.0 6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW61895.1 - 1.1e-06 28.2 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RJW61895.1 - 0.00031 20.7 0.9 0.15 12.0 0.6 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RJW61895.1 - 0.0067 16.0 0.2 0.089 12.3 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RJW61895.1 - 0.052 13.6 0.1 0.095 12.8 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 RJW61895.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 RJW61895.1 - 0.13 12.2 0.1 0.72 9.7 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 RJW61895.1 - 0.85 9.9 2.4 9.5 6.5 0.6 2.5 1 1 1 2 2 2 0 AAA domain Ank_2 PF12796.7 RJW61897.1 - 3e-30 104.6 5.3 1.6e-13 51.0 1.5 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW61897.1 - 2.2e-24 85.2 9.4 1.5e-07 31.5 0.1 6.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW61897.1 - 1e-23 83.4 6.1 3.4e-08 33.9 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RJW61897.1 - 8.5e-22 76.6 8.2 1e-05 25.7 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 RJW61897.1 - 5.1e-21 72.5 5.9 0.00056 20.2 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ion_trans PF00520.31 RJW61897.1 - 2.2e-07 30.4 17.0 4.9e-07 29.2 16.8 1.7 1 1 0 1 1 1 1 Ion transport protein TPP_enzyme_N PF02776.18 RJW61897.1 - 0.012 15.3 1.1 0.15 11.6 0.8 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Forkhead PF00250.18 RJW61898.1 - 2.1e-35 120.9 0.3 4.5e-35 119.8 0.3 1.6 1 0 0 1 1 1 1 Forkhead domain DUF1199 PF06712.11 RJW61898.1 - 1.9 8.6 6.2 4.6 7.3 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) RVT_1 PF00078.27 RJW61899.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SNF PF00209.18 RJW61902.1 - 1.1e-172 575.4 34.0 1.3e-172 575.2 34.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family FLYWCH PF04500.16 RJW61903.1 - 5.2e-11 42.5 0.2 1.9e-10 40.7 0.2 2.0 1 0 0 1 1 1 1 FLYWCH zinc finger domain Parvo_NS1 PF01057.17 RJW61904.1 - 0.053 12.6 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RAG2_PHD PF13341.6 RJW61904.1 - 0.079 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 RAG2 PHD domain Aldolase_II PF00596.21 RJW61905.1 - 3e-38 131.6 0.1 5.8e-38 130.7 0.1 1.5 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain RRM_1 PF00076.22 RJW61906.1 - 5.9e-19 67.7 0.0 1.5e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RJW61906.1 - 0.13 12.2 0.0 3.4 7.6 0.0 2.4 2 1 0 2 2 2 0 Occluded RNA-recognition motif ThiF PF00899.21 RJW61907.1 - 7.3e-60 202.4 0.1 1.4e-59 201.5 0.1 1.4 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 RJW61907.1 - 0.0056 17.2 0.0 0.015 15.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain ApbA PF02558.16 RJW61907.1 - 0.074 12.7 0.3 0.2 11.3 0.3 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 RJW61907.1 - 0.13 11.8 0.5 0.23 11.0 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Longin PF13774.6 RJW61908.1 - 1.7e-19 69.6 0.1 5.6e-19 68.0 0.1 1.9 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 RJW61908.1 - 1.3e-16 60.2 1.3 2.7e-16 59.1 0.6 1.9 2 0 0 2 2 2 1 Synaptobrevin Sec20 PF03908.13 RJW61908.1 - 0.0049 16.7 0.5 0.011 15.6 0.5 1.6 1 0 0 1 1 1 1 Sec20 Pox_EPC_I2-L1 PF12575.8 RJW61908.1 - 0.31 11.3 2.1 0.32 11.3 0.6 1.8 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Med14 PF08638.11 RJW61909.1 - 0.0016 17.9 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit MED14 TRM PF02005.16 RJW61910.1 - 8.2e-109 364.2 0.0 3.6e-92 309.5 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 RJW61910.1 - 1.4e-07 31.5 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 RJW61910.1 - 0.00059 19.5 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_3 PF01596.17 RJW61910.1 - 0.00073 18.8 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_15 PF09445.10 RJW61910.1 - 0.0018 17.8 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 RJW61910.1 - 0.013 14.9 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 RJW61910.1 - 0.024 14.3 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 RJW61910.1 - 0.044 14.5 0.0 0.092 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RJW61910.1 - 0.093 12.3 0.0 0.32 10.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain BCDHK_Adom3 PF10436.9 RJW61912.1 - 5e-41 140.2 0.5 4.6e-40 137.1 0.1 2.1 1 1 1 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RJW61912.1 - 1.5e-08 35.1 0.0 0.004 17.6 0.0 2.3 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tubulin PF00091.25 RJW61915.1 - 4.2e-66 222.9 0.0 5.8e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW61915.1 - 6.8e-50 168.5 0.0 1.1e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW61915.1 - 0.00019 21.2 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Cast PF10174.9 RJW61917.1 - 2.1e-40 138.7 58.6 2.1e-40 138.7 58.6 8.8 4 4 1 6 6 6 2 RIM-binding protein of the cytomatrix active zone Myosin_tail_1 PF01576.19 RJW61917.1 - 0.00097 17.1 36.9 0.00097 17.1 36.9 8.2 4 3 3 7 7 7 3 Myosin tail Tropomyosin_1 PF12718.7 RJW61917.1 - 0.0028 17.8 2.1 0.0028 17.8 2.1 17.0 6 5 10 16 16 16 3 Tropomyosin like Seryl_tRNA_N PF02403.22 RJW61917.1 - 0.0029 17.8 1.7 0.0029 17.8 1.7 19.1 7 5 7 18 18 18 2 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 RJW61917.1 - 0.0029 18.1 11.4 0.0029 18.1 11.4 13.0 3 3 7 11 11 11 4 Fez1 Sulfotransfer_2 PF03567.14 RJW61919.1 - 1.6e-24 87.2 0.1 2.2e-24 86.7 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 RJW61919.1 - 1.2e-06 27.7 2.8 1.5e-05 24.1 1.0 2.1 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Cast PF10174.9 RJW61920.1 - 3.4e-06 25.6 2.0 4.3e-06 25.3 2.0 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF2069 PF09842.9 RJW61920.1 - 0.14 12.4 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) Maf1 PF09174.10 RJW61921.1 - 1.1e-50 172.2 4.0 3e-50 170.8 4.0 1.7 1 1 0 1 1 1 1 Maf1 regulator NAD_binding_5 PF07994.12 RJW61921.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Ufm1 PF03671.14 RJW61922.1 - 6.5e-09 35.7 0.1 1.5e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Pkinase PF00069.25 RJW61926.1 - 1e-63 215.2 0.0 1.5e-63 214.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW61926.1 - 2.5e-27 95.8 0.0 3.8e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HYLS1_C PF15311.6 RJW61926.1 - 8.1e-11 42.5 9.0 9.6e-10 39.1 0.1 3.5 3 0 0 3 3 3 2 Hydrolethalus syndrome protein 1 C-terminus Kinase-like PF14531.6 RJW61926.1 - 6.3e-05 22.4 0.2 0.00057 19.3 0.0 2.1 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RJW61926.1 - 0.0072 15.9 0.2 0.017 14.7 0.2 1.6 1 0 0 1 1 1 1 RIO1 family MBD_C PF14048.6 RJW61926.1 - 0.068 13.9 0.0 0.26 12.0 0.0 2.0 1 0 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 MCM_bind PF09739.9 RJW61927.1 - 9.2e-94 315.0 0.0 1.3e-73 248.5 0.0 2.1 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor GTP_EFTU PF00009.27 RJW61928.1 - 1.5e-34 119.2 0.0 1.5e-34 119.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RJW61928.1 - 6.5e-16 58.4 0.4 1.9e-15 56.9 0.4 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 RJW61928.1 - 2.1e-13 50.0 0.0 5.1e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 RJW61928.1 - 2.5e-11 43.8 2.7 1.6e-06 28.4 0.1 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RJW61928.1 - 2.5e-07 30.8 0.6 1.5e-06 28.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 RJW61928.1 - 0.0055 16.9 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 RJW61928.1 - 0.0066 16.3 0.3 0.052 13.3 0.1 2.6 3 1 0 3 3 3 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 RJW61928.1 - 0.03 14.2 0.1 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 RJW61928.1 - 0.056 13.7 0.0 0.38 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain MIase PF02426.16 RJW61928.1 - 0.14 12.4 2.3 0.96 9.7 1.0 2.9 2 1 0 2 2 2 0 Muconolactone delta-isomerase RhoGEF PF00621.20 RJW61929.1 - 9.3e-18 65.1 0.1 1.1e-16 61.6 0.0 2.6 3 0 0 3 3 3 1 RhoGEF domain Golgin_A5 PF09787.9 RJW61929.1 - 0.02 14.3 5.7 0.033 13.6 2.4 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 Transcrip_act PF04949.13 RJW61929.1 - 0.029 14.3 2.8 0.083 12.8 2.8 1.7 1 0 0 1 1 1 0 Transcriptional activator Fib_alpha PF08702.10 RJW61929.1 - 0.19 11.9 2.6 0.29 11.3 0.8 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Rab5-bind PF09311.11 RJW61929.1 - 0.27 10.6 9.6 0.56 9.5 7.2 2.4 2 0 0 2 2 2 0 Rabaptin-like protein CCDC-167 PF15188.6 RJW61929.1 - 2.3 8.6 8.6 22 5.5 7.6 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Jnk-SapK_ap_N PF09744.9 RJW61929.1 - 2.5 8.3 15.5 1.7 8.8 11.2 2.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4337 PF14235.6 RJW61929.1 - 4.9 7.2 6.4 11 6.1 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TMF_TATA_bd PF12325.8 RJW61929.1 - 6.3 7.0 13.6 9.3 6.5 0.1 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 RJW61929.1 - 7.1 7.0 9.2 20 5.5 9.2 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RVT_1 PF00078.27 RJW61932.1 - 2.2e-15 56.8 0.0 7.6e-15 55.0 0.0 1.9 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_2 PF13347.6 RJW61933.1 - 3.9e-17 61.9 16.2 3.7e-12 45.5 7.8 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 RJW61933.1 - 1.2e-10 40.9 17.3 1e-07 31.2 3.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily COG5 PF10392.9 RJW61934.1 - 6.7e-14 52.2 6.7 6.7e-14 52.2 6.7 2.4 3 0 0 3 3 3 1 Golgi transport complex subunit 5 AIP3 PF03915.13 RJW61934.1 - 0.14 11.3 4.7 0.3 10.1 4.7 1.5 1 0 0 1 1 1 0 Actin interacting protein 3 Myosin_tail_1 PF01576.19 RJW61934.1 - 0.19 9.5 3.8 1 7.1 0.1 2.0 1 1 1 2 2 2 0 Myosin tail DUF713 PF05218.14 RJW61934.1 - 0.21 11.3 6.1 0.28 10.9 4.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF713) PspA_IM30 PF04012.12 RJW61934.1 - 0.24 11.0 2.0 0.47 10.0 2.0 1.4 1 0 0 1 1 1 0 PspA/IM30 family Sec8_exocyst PF04048.14 RJW61934.1 - 0.39 10.6 5.5 0.27 11.1 3.0 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Tropomyosin_1 PF12718.7 RJW61934.1 - 0.43 10.7 3.5 1.2 9.2 3.4 1.8 1 1 0 1 1 1 0 Tropomyosin like DUF4665 PF15679.5 RJW61934.1 - 0.44 11.2 2.3 1.3 9.7 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Exonuc_VII_L PF02601.15 RJW61934.1 - 0.52 9.8 4.6 1.1 8.7 4.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5082 PF16888.5 RJW61934.1 - 1.1 9.6 4.6 2.7 8.3 4.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 RJW61934.1 - 2.8 8.3 7.9 2.2 8.6 1.0 3.6 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vinculin PF01044.19 RJW61935.1 - 4.4e-59 200.7 0.3 7.3e-35 120.5 0.1 2.3 1 1 1 2 2 2 2 Vinculin family RVT_1 PF00078.27 RJW61935.1 - 1.4e-46 158.8 1.0 7.1e-46 156.5 0.0 2.5 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW61935.1 - 7.7e-12 45.1 0.0 5.6e-11 42.3 0.0 2.5 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase RUN PF02759.19 RJW61936.1 - 4.5e-23 81.7 0.0 1.8e-22 79.8 0.0 2.1 1 1 0 1 1 1 1 RUN domain PH_RBD PF12068.8 RJW61936.1 - 2.4e-19 69.4 0.0 7.4e-19 67.8 0.0 1.9 1 0 0 1 1 1 1 Rab-binding domain (RBD) RabGAP-TBC PF00566.18 RJW61936.1 - 4.1e-18 65.8 8.1 7.9e-13 48.6 0.4 4.1 3 1 0 3 3 3 3 Rab-GTPase-TBC domain DUF2193 PF09959.9 RJW61936.1 - 0.051 12.0 0.0 0.079 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) IL4 PF00727.18 RJW61940.1 - 0.0014 18.8 0.1 0.021 15.1 0.0 2.1 2 0 0 2 2 2 1 Interleukin 4 Pou PF00157.17 RJW61942.1 - 4.3e-22 77.9 0.8 9e-22 76.8 0.8 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 RJW61942.1 - 3.8e-13 49.1 0.0 9.4e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 RJW61942.1 - 2.9e-05 24.3 1.6 0.00026 21.3 0.4 2.8 2 1 1 3 3 3 1 Helix-turn-helix domain Homeobox_KN PF05920.11 RJW61942.1 - 0.0065 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.22 RJW61942.1 - 0.08 13.0 0.3 0.62 10.2 0.3 2.5 2 1 0 2 2 2 0 Helix-turn-helix SHNi-TPR PF10516.9 RJW61943.1 - 0.053 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 SHNi-TPR Trypsin PF00089.26 RJW61945.1 - 8e-39 133.7 0.0 3e-38 131.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin DUF316 PF03761.15 RJW61945.1 - 0.00077 19.1 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 Trypsin_2 PF13365.6 RJW61945.1 - 0.0091 16.9 0.0 0.027 15.4 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RJW61946.1 - 4e-48 164.1 0.0 3.1e-34 118.7 0.0 2.0 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 RJW61946.1 - 5.9e-05 24.0 0.0 0.00014 22.8 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain CLTH PF10607.9 RJW61947.1 - 4.8e-10 39.5 0.0 8.3e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain MamL-1 PF09596.10 RJW61948.1 - 0.022 15.0 0.2 0.025 14.8 0.2 1.1 1 0 0 1 1 1 0 MamL-1 domain M20_dimer PF07687.14 RJW61950.1 - 3.5e-12 46.2 0.0 5.2e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 RJW61950.1 - 2.1e-07 30.8 0.0 2.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 LRR_8 PF13855.6 RJW61951.1 - 3.9e-17 61.8 23.1 1.2e-06 28.2 3.8 4.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RJW61951.1 - 4.6e-13 49.1 26.3 1.3e-06 28.6 1.2 4.9 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) B3_4 PF03483.17 RJW61951.1 - 0.0033 17.1 0.0 0.011 15.4 0.0 1.8 1 1 1 2 2 2 1 B3/4 domain LRR_9 PF14580.6 RJW61951.1 - 0.02 14.4 6.0 0.18 11.3 0.6 2.6 1 1 2 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 RJW61951.1 - 0.15 12.2 13.3 5.5 7.3 0.2 5.3 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 RJW61951.1 - 3.3 8.6 16.3 23 6.0 0.8 6.6 5 2 0 5 5 5 0 Leucine Rich Repeat F-box_4 PF15966.5 RJW61952.1 - 1.5e-30 105.5 0.0 3.6e-30 104.2 0.0 1.6 2 0 0 2 2 2 1 F-box zf-TRAF_2 PF15965.5 RJW61952.1 - 5.6e-20 71.6 17.7 2.2e-18 66.5 16.3 2.5 2 0 0 2 2 2 1 TRAF-like zinc-finger zf-TRAF PF02176.18 RJW61952.1 - 2.7e-06 28.0 17.1 0.00012 22.7 8.8 4.6 3 2 1 4 4 4 2 TRAF-type zinc finger Sina PF03145.16 RJW61952.1 - 0.0057 16.6 2.0 0.011 15.7 2.0 1.4 1 0 0 1 1 1 1 Seven in absentia protein family Peptidase_M10 PF00413.24 RJW61953.1 - 1e-49 168.4 0.2 1.5e-49 167.9 0.2 1.2 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 RJW61953.1 - 7.6e-25 86.6 10.9 2.2e-09 37.1 1.2 5.0 4 1 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 RJW61953.1 - 2e-06 27.9 0.0 8.2e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 RJW61953.1 - 0.0024 18.4 0.4 0.0043 17.6 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 RJW61953.1 - 0.012 14.6 0.2 0.02 13.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.6 RJW61953.1 - 0.022 14.9 0.3 0.037 14.2 0.3 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 RJW61953.1 - 0.029 13.0 0.0 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_4 PF13583.6 RJW61953.1 - 0.24 11.0 0.2 0.42 10.2 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ANAPC3 PF12895.7 RJW61954.1 - 2.1e-19 69.5 11.5 2.6e-15 56.4 5.9 4.8 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RJW61954.1 - 2.1e-16 58.6 11.8 0.16 12.1 0.2 10.3 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 RJW61954.1 - 1.1e-13 51.3 18.3 9.5e-05 22.6 0.0 7.7 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 RJW61954.1 - 1.6e-13 49.9 9.3 0.17 11.7 0.0 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 RJW61954.1 - 5.9e-11 41.6 9.1 0.015 15.3 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW61954.1 - 3e-10 40.6 4.2 0.016 15.9 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW61954.1 - 6.8e-10 38.4 7.1 0.89 9.9 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW61954.1 - 8.3e-10 38.7 4.9 0.47 11.4 0.1 7.2 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 RJW61954.1 - 2.4e-09 36.7 0.9 0.28 10.9 0.0 6.6 4 2 2 6 6 6 2 TPR repeat TPR_19 PF14559.6 RJW61954.1 - 8.3e-07 29.4 3.2 0.46 11.0 0.1 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW61954.1 - 0.00022 21.4 2.8 9 6.9 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW61954.1 - 0.00062 19.9 0.3 0.011 15.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 RJW61954.1 - 0.0024 17.1 0.2 15 4.7 0.0 4.2 4 2 1 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 RJW61954.1 - 0.0027 17.7 0.1 0.0087 16.1 0.1 1.9 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_6 PF13174.6 RJW61954.1 - 0.0063 17.1 7.6 17 6.3 0.1 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat FlaC_arch PF05377.11 RJW61954.1 - 0.066 13.6 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PLAC8 PF04749.17 RJW61954.1 - 0.72 10.9 2.9 0.81 10.7 0.2 2.3 2 0 0 2 2 2 0 PLAC8 family Histone_H2A_C PF16211.5 RJW61955.1 - 2.3e-14 52.8 0.2 4e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 RJW61955.1 - 4.3e-14 53.0 0.0 5.8e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RJW61955.1 - 2.1e-05 24.7 0.0 2.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bax1-I PF01027.20 RJW61956.1 - 6.9e-33 114.2 26.1 8.1e-33 114.0 26.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Antimicrobial12 PF08107.11 RJW61956.1 - 0.42 10.4 5.1 0.19 11.5 1.7 2.3 2 0 0 2 2 2 0 Pleurocidin family YfhO PF09586.10 RJW61956.1 - 1 7.5 13.7 1.3 7.2 13.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO BaxI_1 PF12811.7 RJW61956.1 - 1.6 8.3 17.8 2.8 7.5 17.8 1.4 1 1 0 1 1 1 0 Bax inhibitor 1 like DUF1751 PF08551.10 RJW61956.1 - 4.3 8.0 9.1 0.3 11.7 2.3 2.4 1 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DUF2070 PF09843.9 RJW61956.1 - 8.8 4.5 16.0 12 4.0 16.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Kinesin PF00225.23 RJW61958.1 - 8.6e-106 353.6 1.0 8.6e-105 350.3 0.0 2.9 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW61958.1 - 1.1e-21 77.3 0.0 5.6e-21 75.1 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding CSN5_C PF18323.1 RJW61958.1 - 0.017 16.0 0.5 0.017 16.0 0.5 4.6 3 2 1 4 4 4 0 Cop9 signalosome subunit 5 C-terminal domain Spc42p PF11544.8 RJW61958.1 - 0.15 12.1 4.6 0.87 9.6 0.1 4.2 3 1 2 5 5 5 0 Spindle pole body component Spc42p Tyrosinase PF00264.20 RJW61962.1 - 2.6e-32 112.9 0.1 5.3e-32 111.9 0.1 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase LANC_like PF05147.13 RJW61963.1 - 9.5e-63 211.9 0.0 1.1e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_88 PF07470.13 RJW61963.1 - 0.00054 19.1 0.0 0.00098 18.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 RJW61963.1 - 0.02 13.4 0.0 0.41 9.1 0.1 2.1 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 RJW61963.1 - 0.05 13.1 0.0 0.68 9.4 0.0 2.2 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus DUF3539 PF12058.8 RJW61963.1 - 0.18 12.0 0.0 0.47 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3539) Cytochrome_CBB3 PF13442.6 RJW61963.1 - 0.3 11.4 1.6 0.89 9.9 0.1 2.5 2 1 1 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III INPP5B_PH PF16776.5 RJW61964.1 - 0.036 13.8 0.1 0.17 11.6 0.1 2.0 1 1 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Mito_carr PF00153.27 RJW61968.1 - 9.4e-66 217.8 0.0 1.4e-23 82.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Gp_dh_C PF02800.20 RJW61969.1 - 1e-68 229.9 0.0 1.5e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 RJW61969.1 - 3e-37 127.0 0.0 9.5e-37 125.4 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 RJW61969.1 - 0.071 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sds3 PF08598.11 RJW61970.1 - 5.3e-13 49.5 2.3 7.9e-13 48.9 2.3 1.4 1 0 0 1 1 1 1 Sds3-like zf-C4H2 PF10146.9 RJW61970.1 - 0.0072 16.7 6.4 0.0099 16.2 6.4 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein RPN7 PF10602.9 RJW61970.1 - 0.036 13.8 1.7 0.073 12.8 1.1 1.8 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Syntaxin-6_N PF09177.11 RJW61970.1 - 0.62 10.6 5.9 0.37 11.4 2.3 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fe-S_biosyn PF01521.20 RJW61971.1 - 1.4e-14 54.2 0.0 2.1e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NUDIX PF00293.28 RJW61972.1 - 1.1e-12 48.1 0.0 2.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain MKRN1_C PF15815.5 RJW61973.1 - 0.067 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal zf-C2H2_4 PF13894.6 RJW61975.1 - 1.5e-23 81.4 52.6 0.0016 19.1 2.2 7.8 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW61975.1 - 1.3e-22 79.0 56.2 7.8e-05 22.9 3.1 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW61975.1 - 9.6e-17 60.6 42.5 0.0039 17.6 0.5 8.1 8 1 0 8 8 7 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW61975.1 - 3.9e-15 55.7 28.0 0.055 13.8 0.6 7.5 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW61975.1 - 2.4e-12 46.8 32.1 0.016 15.6 0.6 7.8 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RJW61975.1 - 3.4e-12 46.0 38.6 0.013 15.4 1.5 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-Di19 PF05605.12 RJW61975.1 - 9.2e-10 38.7 33.5 6.8e-05 23.1 0.9 5.3 3 1 3 6 6 6 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 RJW61975.1 - 0.00017 21.3 41.2 0.033 13.9 2.2 7.3 7 0 0 7 7 7 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 RJW61975.1 - 0.00017 22.2 19.3 0.0069 17.1 0.1 4.4 2 2 1 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 RJW61975.1 - 0.0013 18.3 22.4 0.41 10.3 0.1 7.2 8 0 0 8 8 7 2 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 RJW61975.1 - 0.0044 16.6 22.6 0.031 13.9 1.2 5.5 2 2 4 6 6 6 3 Zinc-fingers and homeoboxes C2H2 finger domain Zn-ribbon_8 PF09723.10 RJW61975.1 - 0.011 15.9 0.7 0.011 15.9 0.7 5.5 6 1 0 6 6 5 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 RJW61975.1 - 0.011 16.0 32.7 5.2 7.5 0.7 6.9 2 2 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.6 RJW61975.1 - 0.032 14.1 1.5 0.032 14.1 1.5 4.2 5 0 0 5 5 4 0 Probable zinc-ribbon domain Rad50_zn_hook PF04423.14 RJW61975.1 - 0.33 10.8 6.6 5.9 6.8 0.4 3.2 2 1 1 3 3 3 0 Rad50 zinc hook motif zf-C2H2_8 PF15909.5 RJW61975.1 - 0.72 10.2 26.2 0.082 13.2 4.1 4.2 2 2 2 4 4 4 0 C2H2-type zinc ribbon Elf1 PF05129.13 RJW61975.1 - 0.95 9.6 24.2 1.9 8.6 1.2 5.3 2 2 3 5 5 5 0 Transcription elongation factor Elf1 like zf-MYST PF17772.1 RJW61975.1 - 1.5 8.5 13.1 2 8.1 0.0 4.6 4 2 2 6 6 5 0 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 RJW61975.1 - 3.5 7.7 23.1 7.3 6.7 0.4 6.0 6 1 0 6 6 6 0 Sec23/Sec24 zinc finger zf-LYAR PF08790.11 RJW61975.1 - 3.7 7.5 28.4 5.9 6.9 0.3 6.7 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger zf-C2H2_9 PF16293.5 RJW61975.1 - 5.9 6.8 12.4 16 5.4 0.0 5.3 6 0 0 6 6 5 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 RJW61975.1 - 8.9 6.4 35.0 0.96 9.5 0.1 6.2 5 1 2 7 7 7 0 BED zinc finger FRG PF08867.11 RJW61976.1 - 0.11 13.4 0.1 0.23 12.5 0.1 1.5 1 0 0 1 1 1 0 FRG domain Adaptin_N PF01602.20 RJW61977.1 - 0.062 11.9 0.4 4.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 RJW61977.1 - 0.17 12.5 2.6 57 4.4 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 RJW61977.1 - 0.19 12.0 3.8 5 7.6 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Mito_carr PF00153.27 RJW61978.1 - 9.5e-09 35.1 0.1 2.3e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial carrier protein IQ PF00612.27 RJW61980.1 - 2.7e-05 23.6 0.0 7.5e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif WXG100 PF06013.12 RJW61980.1 - 0.79 10.0 11.7 0.43 10.8 2.3 3.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG CK_II_beta PF01214.18 RJW61980.1 - 7.1 6.4 8.4 0.35 10.7 1.4 2.2 1 1 1 2 2 2 0 Casein kinase II regulatory subunit SAM_2 PF07647.17 RJW61982.1 - 3.5e-20 71.9 1.6 9.4e-12 44.9 0.1 3.0 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RJW61982.1 - 1.4e-13 51.0 0.7 6.9e-10 39.2 0.1 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 RJW61982.1 - 2.7e-10 40.9 0.0 6.9e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 TIR domain Prot_ATP_ID_OB PF16450.5 RJW61984.1 - 8.7e-10 38.4 0.0 2.7e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain Prot_ATP_OB_N PF17758.1 RJW61984.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain ANAPC4_WD40 PF12894.7 RJW61985.1 - 1.7e-05 25.1 0.0 0.28 11.5 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW61985.1 - 0.021 15.7 5.9 12 6.9 1.7 4.7 5 1 0 5 5 5 0 WD domain, G-beta repeat Peptidase_M48_N PF16491.5 RJW61987.1 - 2.4e-61 206.8 10.0 2.4e-61 206.8 10.0 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 RJW61987.1 - 2.5e-52 177.5 0.0 6.5e-52 176.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 PT PF04886.12 RJW61988.1 - 3.2e-37 125.8 122.6 1.8e+04 -34.2 122.6 4.4 1 1 0 1 1 1 0 PT repeat Presenilin PF01080.17 RJW61988.1 - 0.04 12.7 2.0 0.047 12.4 2.0 1.2 1 0 0 1 1 1 0 Presenilin CwfJ_C_1 PF04677.15 RJW61989.1 - 7.2e-26 90.5 0.0 1.3e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 RJW61989.1 - 3.8e-18 66.2 0.0 9.3e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-H2C2_2 PF13465.6 RJW61990.1 - 5.8e-12 45.5 6.9 6.5e-07 29.5 0.6 5.8 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2 PF00096.26 RJW61990.1 - 4.5e-08 33.1 52.1 0.00017 21.8 3.0 6.7 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RJW61990.1 - 4.5e-05 23.1 13.0 0.00039 20.1 0.5 4.4 4 1 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RJW61990.1 - 0.0064 17.2 61.5 0.013 16.2 2.5 7.7 8 1 0 8 8 8 5 C2H2-type zinc finger HTH_AraC PF00165.23 RJW61990.1 - 0.037 14.1 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family NHL PF01436.21 RJW61991.1 - 4.4e-21 73.8 12.3 2.7e-06 27.1 0.0 6.3 6 0 0 6 6 6 4 NHL repeat zf-RING_UBOX PF13445.6 RJW61991.1 - 4.3e-09 36.3 1.5 4.3e-09 36.3 1.5 3.6 3 1 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 RJW61991.1 - 3.1e-06 27.2 7.1 3.1e-06 27.2 7.1 3.4 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 RJW61991.1 - 7.1e-05 22.6 4.0 7.1e-05 22.6 4.0 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF5128 PF17170.4 RJW61991.1 - 0.00011 21.5 0.4 0.048 12.8 0.0 3.1 3 0 0 3 3 3 1 6-bladed beta-propeller zf-C3HC4_4 PF15227.6 RJW61991.1 - 0.00033 20.8 4.6 0.00033 20.8 4.6 4.0 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RJW61991.1 - 0.004 17.0 2.7 0.004 17.0 2.7 3.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RJW61991.1 - 0.013 15.3 4.6 0.013 15.3 4.6 3.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Mu-like_Com PF10122.9 RJW61991.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com OrfB_Zn_ribbon PF07282.11 RJW61991.1 - 0.96 9.4 6.7 3 7.8 3.8 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Phospholip_B PF04916.13 RJW61993.1 - 9.9e-155 516.1 4.3 1.2e-154 515.8 4.3 1.0 1 0 0 1 1 1 1 Phospholipase B CTP_transf_like PF01467.26 RJW61994.1 - 3e-32 111.8 0.1 1.1e-31 109.9 0.0 2.0 2 1 1 3 3 3 1 Cytidylyltransferase-like SPAM PF02090.15 RJW61994.1 - 0.052 13.4 0.1 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein Robl_LC7 PF03259.17 RJW61995.1 - 4.8e-11 42.3 0.0 7.6e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain RT_RNaseH_2 PF17919.1 RJW61995.1 - 0.071 13.2 0.2 0.14 12.2 0.1 1.5 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase GlcNAc_2-epim PF07221.11 RJW61995.1 - 0.16 11.2 0.2 0.32 10.2 0.2 1.6 1 1 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Pep3_Vps18 PF05131.14 RJW61996.1 - 1.3e-31 109.4 0.0 2.8e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family zf-RING_11 PF17123.5 RJW61996.1 - 0.0083 15.8 1.2 0.032 14.0 1.2 2.1 1 0 0 1 1 1 1 RING-like zinc finger Clathrin PF00637.20 RJW61996.1 - 0.042 13.7 0.1 0.26 11.1 0.0 2.4 3 0 0 3 3 3 0 Region in Clathrin and VPS zf-RING_5 PF14634.6 RJW61996.1 - 0.081 12.9 2.5 0.24 11.4 2.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RJW61996.1 - 0.092 12.6 4.6 0.32 10.9 4.6 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 RJW61996.1 - 0.11 12.9 0.7 0.31 11.5 0.7 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 RJW61996.1 - 0.23 11.5 1.3 0.79 9.8 1.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 RJW61996.1 - 0.27 11.1 2.0 1 9.3 2.0 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Snapin_Pallidin PF14712.6 RJW61996.1 - 0.29 11.6 0.9 0.89 10.0 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin zf-RING_2 PF13639.6 RJW61996.1 - 0.81 10.1 4.7 4.1 7.8 4.7 2.3 1 1 0 1 1 1 0 Ring finger domain Corona_3 PF04694.12 RJW61997.1 - 0.072 13.4 0.0 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 Coronavirus ORF3 protein Alpha_kinase PF02816.18 RJW61998.1 - 1.2e-58 198.3 0.0 1.9e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Aminotran_1_2 PF00155.21 RJW62002.1 - 1.1e-38 133.4 0.0 1.3e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II 7tm_1 PF00001.21 RJW62003.1 - 2.1e-12 47.0 19.0 2.1e-12 47.0 19.0 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Tubulin PF00091.25 RJW62004.1 - 2.3e-63 214.0 0.0 3.7e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW62004.1 - 5.3e-44 149.4 0.2 8.8e-44 148.7 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RJW62004.1 - 0.0052 17.1 0.0 0.014 15.7 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RJW62004.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 RJW62004.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin like DNA_pack_N PF02500.15 RJW62005.1 - 0.02 14.8 0.1 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Ephrin PF00812.17 RJW62005.1 - 0.072 13.1 1.2 0.12 12.3 1.0 1.6 1 1 0 1 1 1 0 Ephrin Myb_DNA-binding PF00249.31 RJW62006.1 - 7.5e-06 26.0 0.1 1.4e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RJW62006.1 - 0.00024 20.9 0.2 0.00049 19.9 0.2 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Phage_Mu_Gam PF07352.12 RJW62006.1 - 0.056 13.4 2.2 0.083 12.8 2.2 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Mit_KHE1 PF10173.9 RJW62006.1 - 0.11 12.5 0.5 0.16 12.0 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF1664 PF07889.12 RJW62006.1 - 0.13 12.3 0.7 0.2 11.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran_Xtn PF12848.7 RJW62006.1 - 0.29 11.2 2.1 0.62 10.1 2.1 1.5 1 0 0 1 1 1 0 ABC transporter Ephrin PF00812.17 RJW62007.1 - 2.9e-11 43.5 0.1 7.8e-11 42.1 0.1 1.8 1 0 0 1 1 1 1 Ephrin zf-C2H2_2 PF12756.7 RJW62009.1 - 0.0068 16.7 14.1 5.3 7.4 0.6 4.6 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 RJW62009.1 - 0.013 16.3 33.6 0.26 12.2 3.7 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RJW62009.1 - 0.016 15.0 3.2 0.016 15.0 3.2 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain TPR_2 PF07719.17 RJW62012.1 - 6.1e-15 54.1 0.9 1.1e-06 28.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RJW62012.1 - 7.2e-15 54.1 0.2 1.9e-07 30.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RJW62012.1 - 1.4e-08 34.3 0.0 3.9e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 RJW62012.1 - 7e-07 29.5 2.2 0.0033 18.1 0.0 3.3 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW62012.1 - 9.3e-07 29.1 0.9 0.009 16.3 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW62012.1 - 9.5e-06 25.4 0.0 0.0001 22.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW62012.1 - 1e-05 26.1 1.3 3.4e-05 24.4 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW62012.1 - 1.4e-05 25.2 0.4 5.2e-05 23.3 0.3 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat CS PF04969.16 RJW62012.1 - 6.3e-05 23.9 0.1 0.0002 22.3 0.1 1.9 1 0 0 1 1 1 1 CS domain TPR_19 PF14559.6 RJW62012.1 - 9.2e-05 22.9 0.3 0.00031 21.2 0.0 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW62012.1 - 0.026 14.5 0.1 0.27 11.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW62012.1 - 0.064 13.9 0.4 0.39 11.4 0.0 2.6 3 0 0 3 3 1 0 Tetratricopeptide repeat ASH PF15780.5 RJW62012.1 - 0.13 12.5 0.3 0.25 11.6 0.3 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Skp1_POZ PF03931.15 RJW62015.1 - 2.3e-07 30.9 0.0 2.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Acetyltransf_13 PF13880.6 RJW62017.1 - 2.8e-26 91.3 0.0 5e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 RJW62017.1 - 0.00088 19.7 0.0 0.0027 18.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RJW62017.1 - 0.0028 17.9 0.0 0.0052 17.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RJW62017.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Alg6_Alg8 PF03155.15 RJW62018.1 - 1e-88 298.5 26.7 1.4e-88 298.0 26.7 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RVT_1 PF00078.27 RJW62018.1 - 0.097 12.2 0.0 0.27 10.7 0.0 1.8 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 RJW62019.1 - 0.0013 18.1 18.8 0.0015 17.9 17.0 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF4389 PF14333.6 RJW62019.1 - 0.32 10.9 7.6 3.6 7.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) PHO4 PF01384.20 RJW62019.1 - 0.34 9.9 0.0 0.34 9.9 0.0 2.3 2 1 0 2 2 2 0 Phosphate transporter family UCH PF00443.29 RJW62020.1 - 8e-47 159.9 0.0 1.2e-46 159.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW62020.1 - 7.7e-15 55.3 0.2 1.1e-14 54.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RJW62020.1 - 0.00021 21.5 9.3 0.00021 21.5 9.3 3.5 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 RJW62020.1 - 0.0068 15.9 1.1 0.083 12.4 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ion_trans_2 PF07885.16 RJW62022.1 - 1.2e-16 60.4 2.9 1.9e-16 59.7 2.9 1.3 1 0 0 1 1 1 1 Ion channel Bax1-I PF01027.20 RJW62022.1 - 2 8.2 4.7 5.4 6.8 4.4 1.7 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Asparaginase_2 PF01112.18 RJW62023.1 - 8.7e-53 179.3 0.0 1.5e-52 178.5 0.0 1.3 1 1 0 1 1 1 1 Asparaginase ANAPC4_WD40 PF12894.7 RJW62024.1 - 0.00079 19.7 0.0 0.018 15.3 0.0 3.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW62024.1 - 0.068 14.1 0.0 5.8 8.0 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Ribosomal_S8e PF01201.22 RJW62025.1 - 3.4e-53 179.5 0.9 4.4e-53 179.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e EIF4E-T PF10477.9 RJW62027.1 - 5.2e-06 25.6 6.7 5.2e-06 25.6 6.7 3.1 1 1 2 3 3 3 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PAT1 PF09770.9 RJW62027.1 - 0.0028 16.0 3.8 0.004 15.5 3.8 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 PP2C PF00481.21 RJW62028.1 - 1e-70 238.3 0.0 1.4e-57 195.3 0.0 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 RJW62028.1 - 0.0012 18.5 0.1 0.0077 15.9 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RJW62028.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Sas10_Utp3 PF04000.15 RJW62029.1 - 9.7e-10 39.0 0.0 2.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF1217 PF06748.12 RJW62029.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) DHHC PF01529.20 RJW62031.1 - 1.6e-37 128.6 12.0 1.6e-37 128.6 12.0 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 RJW62031.1 - 1.3 9.2 4.8 2.3 8.4 4.8 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger C2 PF00168.30 RJW62035.1 - 0.00012 22.3 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain IBR PF01485.21 RJW62037.1 - 5.9e-20 71.3 34.9 5.8e-11 42.4 4.5 4.0 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 RJW62037.1 - 0.014 15.7 39.6 0.019 15.3 14.7 4.8 4 0 0 4 4 4 0 Ring finger domain zf-C3HC4_2 PF13923.6 RJW62037.1 - 0.051 13.4 0.5 0.051 13.4 0.5 4.8 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.19 RJW62038.1 - 3.6e-19 69.1 2.8 4.6e-19 68.8 2.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein SBF PF01758.16 RJW62039.1 - 2e-15 57.0 4.3 2e-15 57.0 4.3 2.3 2 1 1 3 3 3 1 Sodium Bile acid symporter family OAD_beta PF03977.13 RJW62039.1 - 0.0084 15.1 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Na+-transporting oxaloacetate decarboxylase beta subunit Mem_trans PF03547.18 RJW62039.1 - 0.026 12.9 2.6 0.12 10.7 0.5 2.2 2 0 0 2 2 2 0 Membrane transport protein TPR_1 PF00515.28 RJW62040.1 - 2.9e-15 55.3 0.8 1.2e-06 28.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW62040.1 - 8.1e-14 50.6 1.2 0.0043 17.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RJW62040.1 - 8.1e-07 28.6 0.1 0.18 11.5 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 RJW62040.1 - 4.2e-06 26.8 4.1 0.00099 19.2 1.8 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW62040.1 - 5.1e-05 23.5 3.5 0.042 14.1 1.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW62040.1 - 8.5e-05 22.5 1.5 0.42 11.0 0.1 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW62040.1 - 0.0005 20.7 1.6 0.95 10.2 0.4 2.9 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RJW62040.1 - 0.00061 20.2 3.8 0.065 13.8 0.2 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 RJW62040.1 - 0.0046 16.2 3.9 0.25 10.5 0.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW62040.1 - 0.0056 17.4 1.9 20 6.4 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW62040.1 - 0.039 14.0 3.4 4.9 7.4 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_ligase_aden PF01653.18 RJW62040.1 - 0.051 12.6 0.2 0.094 11.8 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain MAS20 PF02064.15 RJW62040.1 - 0.06 13.4 0.8 0.18 11.9 0.2 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor TPR_17 PF13431.6 RJW62040.1 - 0.11 12.9 0.5 36 5.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RJW62040.1 - 0.2 11.7 2.8 50 4.1 0.0 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 RJW62040.1 - 1.9 9.3 4.1 1.1e+02 3.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat CCDC-167 PF15188.6 RJW62040.1 - 7 7.1 11.4 1.2 9.5 0.2 3.3 1 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 Ribosomal_L18p PF00861.22 RJW62041.1 - 0.00011 22.6 0.0 0.00016 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast RhoGAP PF00620.27 RJW62042.1 - 4.2e-35 120.8 0.0 6.9e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain SPATA48 PF15073.6 RJW62043.1 - 0.0032 17.7 0.3 0.0046 17.2 0.3 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 FSA_C PF10479.9 RJW62043.1 - 0.042 12.0 0.0 0.047 11.8 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pkinase_Tyr PF07714.17 RJW62044.1 - 9.1e-39 133.3 0.0 1.5e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW62044.1 - 3.7e-19 69.1 0.0 2.4e-18 66.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 RJW62044.1 - 0.00067 20.2 0.1 0.61 10.7 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RJW62044.1 - 0.01 16.0 0.0 0.093 12.9 0.0 2.5 2 1 0 2 2 2 0 Immunoglobulin V-set domain Ig_2 PF13895.6 RJW62044.1 - 0.025 14.9 1.7 17 5.8 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin domain MA3 PF02847.17 RJW62046.1 - 1.4e-40 137.8 0.2 2.7e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 MA3 domain Cadherin PF00028.17 RJW62047.1 - 2.3e-76 252.3 1.6 1.3e-14 54.4 0.2 8.2 7 1 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RJW62047.1 - 1.7e-17 63.0 0.0 1.1e-09 38.0 0.0 5.1 5 0 0 5 5 5 3 Cadherin-like Cadherin_3 PF16184.5 RJW62047.1 - 2e-06 27.7 8.4 0.019 15.0 0.5 5.2 5 0 0 5 5 5 2 Cadherin-like RET_CLD1 PF17756.1 RJW62047.1 - 0.00062 20.1 0.0 7.8 6.8 0.0 4.4 4 0 0 4 4 4 1 RET Cadherin like domain 1 Cadherin_4 PF17803.1 RJW62047.1 - 0.0044 17.6 7.1 1.3 9.7 1.0 3.9 3 0 0 3 3 3 2 Bacterial cadherin-like domain SHMT PF00464.19 RJW62048.1 - 4.9e-164 545.7 0.0 6.1e-164 545.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase RVT_1 PF00078.27 RJW62049.1 - 3e-45 154.4 0.0 5.3e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW62049.1 - 0.0014 18.2 1.5 0.0028 17.2 1.5 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SLBP_RNA_bind PF15247.6 RJW62051.1 - 1e-25 89.6 3.6 2.3e-25 88.5 3.6 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain E1-E2_ATPase PF00122.20 RJW62052.1 - 1e-47 162.0 2.8 1.2e-47 161.7 0.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RJW62052.1 - 5e-34 118.4 0.0 2.9e-19 70.2 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HMA PF00403.26 RJW62052.1 - 1.1e-28 99.5 1.8 4.6e-09 36.6 0.1 5.2 5 1 0 5 5 5 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 RJW62052.1 - 0.00034 20.4 0.2 0.0038 17.0 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 RJW62052.1 - 0.00086 19.4 0.1 1.3 9.2 0.0 3.4 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 RJW62052.1 - 0.011 16.1 0.1 0.33 11.3 0.1 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase BEN PF10523.9 RJW62053.1 - 2.8e-06 27.4 0.0 5.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 BEN domain Sedlin_N PF04628.13 RJW62054.1 - 4.1e-20 72.2 0.0 6.6e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 RJW62054.1 - 0.15 12.0 0.0 3 7.8 0.0 2.1 2 0 0 2 2 2 0 Sybindin-like family Oxysterol_BP PF01237.18 RJW62055.1 - 1.1e-133 445.7 0.1 2.6e-129 431.3 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein RVT_1 PF00078.27 RJW62055.1 - 2.3e-28 99.3 0.0 4.9e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-F_leu_zip PF10473.9 RJW62055.1 - 0.053 13.5 11.8 0.096 12.7 1.2 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.17 RJW62055.1 - 0.09 12.7 4.7 0.11 12.4 0.7 2.5 2 0 0 2 2 2 0 Prefoldin subunit Snapin_Pallidin PF14712.6 RJW62055.1 - 0.21 12.0 5.8 0.063 13.7 0.9 2.3 2 0 0 2 2 2 0 Snapin/Pallidin SlyX PF04102.12 RJW62055.1 - 1.5 9.5 6.8 6.1 7.5 1.3 2.8 2 0 0 2 2 2 0 SlyX Hrs_helical PF12210.8 RJW62055.1 - 2.6 8.7 6.0 0.65 10.6 2.0 2.1 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DivIC PF04977.15 RJW62055.1 - 4.5 7.1 5.7 1.5 8.6 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator Mcl1_mid PF12341.8 RJW62056.1 - 1.3e-70 238.1 0.0 9.3e-70 235.3 0.0 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 RJW62056.1 - 8.1e-08 32.8 9.7 3.1e-06 27.8 0.0 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW62056.1 - 3.4e-06 27.3 0.1 0.39 11.0 0.0 4.2 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW62056.1 - 0.01 14.8 0.1 1.8 7.4 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Amelogenin PF02948.15 RJW62056.1 - 0.097 13.3 1.4 4.1 8.0 0.3 2.5 2 0 0 2 2 2 0 Amelogenin HMG_box PF00505.19 RJW62056.1 - 0.098 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box Prolactin_RP PF15172.6 RJW62056.1 - 0.17 11.5 0.1 0.46 10.1 0.1 1.7 1 0 0 1 1 1 0 Prolactin-releasing peptide Ima1_N PF09779.9 RJW62056.1 - 0.53 11.1 2.1 3.2 8.6 0.2 2.5 2 0 0 2 2 2 0 Ima1 N-terminal domain DUF3523 PF12037.8 RJW62057.1 - 3.8e-85 285.5 38.0 1.9e-84 283.2 38.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 RJW62057.1 - 2.4e-22 79.8 0.0 4.7e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RJW62057.1 - 6.4e-05 23.1 2.3 8.7e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 RJW62057.1 - 0.00024 21.2 0.0 0.00064 19.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 RJW62057.1 - 0.00036 21.0 3.1 0.0016 18.9 0.0 3.0 2 2 0 2 2 1 1 AAA ATPase domain Mg_chelatase PF01078.21 RJW62057.1 - 0.00038 19.9 0.1 0.002 17.6 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 RJW62057.1 - 0.00046 20.0 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RJW62057.1 - 0.0014 18.9 1.7 1.3 9.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 RJW62057.1 - 0.0036 17.3 0.7 0.012 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RJW62057.1 - 0.0059 17.2 0.0 0.031 14.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RJW62057.1 - 0.019 14.7 0.0 0.063 13.0 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 RJW62057.1 - 0.022 14.7 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 RJW62057.1 - 0.039 13.8 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 RJW62057.1 - 0.064 12.8 0.1 0.27 10.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RJW62057.1 - 0.07 13.5 0.0 0.46 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 RJW62057.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 RJW62057.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RJW62057.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.3 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RJW62057.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 RJW62057.1 - 0.62 9.8 0.0 0.62 9.8 0.0 3.2 2 1 0 2 2 1 0 AAA domain Gal-bind_lectin PF00337.22 RJW62058.1 - 0.00021 20.8 0.0 0.00063 19.3 0.0 1.9 1 1 0 1 1 1 1 Galactoside-binding lectin PID PF00640.23 RJW62060.1 - 1.7e-33 115.6 0.0 8.3e-33 113.4 0.0 2.0 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 RJW62060.1 - 4.4e-23 81.4 0.2 2.4e-11 43.8 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RJW62060.1 - 6.3e-12 45.2 0.3 4e-06 26.6 0.1 2.8 2 0 0 2 2 2 2 PDZ domain NRho PF16733.5 RJW62060.1 - 0.026 14.6 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 Rhomboid N-terminal domain DSL PF01414.19 RJW62062.1 - 1.1e-10 41.7 4.6 1.1e-10 41.7 4.6 3.8 4 0 0 4 4 4 1 Delta serrate ligand EGF PF00008.27 RJW62062.1 - 6.3e-10 39.2 13.9 5.8e-06 26.5 2.7 5.0 6 0 0 6 6 6 3 EGF-like domain hEGF PF12661.7 RJW62062.1 - 0.00012 22.6 4.4 0.00012 22.6 4.4 5.0 4 0 0 4 4 4 2 Human growth factor-like EGF EGF_2 PF07974.13 RJW62062.1 - 0.0023 18.3 5.9 0.0023 18.3 5.9 5.0 5 0 0 5 5 5 2 EGF-like domain TAFA PF12020.8 RJW62062.1 - 0.013 16.0 1.6 0.013 16.0 1.6 3.9 2 1 2 4 4 4 0 TAFA family MLANA PF14991.6 RJW62062.1 - 0.065 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A SKG6 PF08693.10 RJW62062.1 - 0.065 12.7 0.7 0.12 11.8 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-B_box PF00643.24 RJW62064.1 - 2.4e-06 27.6 21.7 1.1e-05 25.5 10.3 5.1 8 0 0 8 8 8 2 B-box zinc finger PHD PF00628.29 RJW62064.1 - 0.0013 18.6 7.0 0.0013 18.6 7.0 5.2 4 1 0 4 4 4 2 PHD-finger Tnp_zf-ribbon_2 PF13842.6 RJW62064.1 - 0.0097 16.7 6.1 0.0097 16.7 6.1 5.0 5 1 0 5 5 5 1 DDE_Tnp_1-like zinc-ribbon GDPD PF03009.17 RJW62064.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Pkinase_Tyr PF07714.17 RJW62065.1 - 1.1e-53 182.2 0.0 1.6e-53 181.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW62065.1 - 2.3e-43 148.5 0.0 1.5e-42 145.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain SAM_KSR1 PF13543.6 RJW62065.1 - 4.9e-05 23.5 0.0 8.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Kinase-like PF14531.6 RJW62065.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RJW62065.1 - 0.0097 15.3 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW62065.1 - 0.19 11.6 0.2 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family C1_1 PF00130.22 RJW62065.1 - 0.27 11.2 8.7 0.67 9.9 8.7 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) s48_45 PF07422.13 RJW62066.1 - 0.072 13.7 0.0 0.24 12.0 0.0 1.8 2 0 0 2 2 2 0 Sexual stage antigen s48/45 domain 7tm_1 PF00001.21 RJW62068.1 - 2.1e-08 33.8 11.8 3.9e-08 32.9 11.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LisH_2 PF16045.5 RJW62069.1 - 0.69 9.0 3.3 1.9 7.6 0.1 2.6 3 0 0 3 3 3 0 LisH V-set PF07686.17 RJW62070.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain MCM PF00493.23 RJW62071.1 - 7.9e-101 335.8 0.0 1.2e-100 335.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 RJW62071.1 - 1.8e-29 102.0 0.1 1.4e-28 99.1 0.4 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_OB PF17207.3 RJW62071.1 - 9.6e-18 64.2 0.0 2e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 RJW62071.1 - 6.3e-11 42.1 0.0 9.5e-08 31.7 0.0 2.9 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RJW62071.1 - 1.5e-07 31.3 0.0 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RJW62071.1 - 5.4e-07 29.7 0.0 1.8e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 RJW62071.1 - 0.0018 18.7 0.1 0.0052 17.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RJW62071.1 - 0.0046 16.7 0.1 0.63 9.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_lid_2 PF17863.1 RJW62071.1 - 0.051 13.4 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA lid domain AAA_16 PF13191.6 RJW62071.1 - 0.14 12.5 0.1 4.9 7.5 0.1 2.7 2 2 0 2 2 2 0 AAA ATPase domain Bromodomain PF00439.25 RJW62073.1 - 4e-91 299.2 15.1 1.7e-20 72.9 0.1 5.6 5 0 0 5 5 5 5 Bromodomain BAH PF01426.18 RJW62073.1 - 1.1e-29 102.7 0.0 4.6e-15 55.6 0.0 2.6 2 0 0 2 2 2 2 BAH domain HMG_box PF00505.19 RJW62073.1 - 5e-11 42.9 0.3 1.2e-10 41.6 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW62073.1 - 5.6e-10 39.7 1.6 1.4e-09 38.4 1.6 1.6 1 0 0 1 1 1 1 HMG-box domain AT_hook PF02178.19 RJW62073.1 - 0.059 13.3 4.5 0.23 11.5 4.5 2.1 1 0 0 1 1 1 0 AT hook motif ERCC4 PF02732.15 RJW62075.1 - 8.8e-25 87.7 0.0 1.5e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain VWA_3 PF13768.6 RJW62075.1 - 0.12 12.3 0.1 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF974 PF06159.13 RJW62076.1 - 2.9e-53 181.2 0.0 4.9e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 RJW62076.1 - 1e-05 25.2 0.1 0.64 9.4 0.0 4.0 3 1 1 4 4 4 2 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 RJW62076.1 - 0.15 12.2 0.1 7.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain RFXA_RFXANK_bdg PF15289.6 RJW62078.1 - 1.3e-13 51.4 0.3 7.1e-13 49.0 0.3 1.9 1 1 0 1 1 1 1 Regulatory factor X-associated C-terminal binding domain P_C PF06640.11 RJW62078.1 - 0.14 12.3 1.8 0.5 10.5 2.0 1.7 2 0 0 2 2 2 0 P protein C-terminus Carb_anhydrase PF00194.21 RJW62079.1 - 3.5e-21 75.9 0.0 3.9e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase VIT PF08487.10 RJW62080.1 - 1.1e-28 99.7 0.2 2.7e-28 98.4 0.2 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 RJW62080.1 - 4e-22 78.8 0.0 9.9e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain DSL PF01414.19 RJW62080.1 - 9.5e-12 45.0 5.1 9.5e-12 45.0 5.1 2.4 2 0 0 2 2 2 1 Delta serrate ligand VIT_2 PF13757.6 RJW62080.1 - 1.4e-11 44.1 0.0 3.6e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 RJW62080.1 - 1.1e-09 38.9 0.0 3.5e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RJW62080.1 - 5.8e-09 36.4 0.0 1.2e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 RJW62080.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus TMEM173 PF15009.6 RJW62080.1 - 0.12 11.5 0.0 0.34 10.0 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 173 Ion_trans_2 PF07885.16 RJW62081.1 - 3.9e-09 36.3 0.6 9.4e-09 35.1 0.6 1.6 1 0 0 1 1 1 1 Ion channel RVT_1 PF00078.27 RJW62082.1 - 1.6e-08 34.3 0.0 4e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW62082.1 - 5.6e-06 26.2 0.0 1.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW62082.1 - 0.0012 18.4 1.5 0.0024 17.5 1.5 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Apolipoprotein PF01442.18 RJW62082.1 - 0.2 11.5 13.3 0.043 13.7 9.0 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain ABC_membrane PF00664.23 RJW62083.1 - 4.5e-41 141.3 5.4 6e-41 140.9 5.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RJW62083.1 - 3.1e-31 108.7 0.0 6.3e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RJW62083.1 - 1.4e-08 34.5 1.1 7.3e-07 28.9 0.5 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RJW62083.1 - 7.3e-05 23.2 0.1 0.0002 21.8 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RJW62083.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 RJW62083.1 - 0.0046 16.2 0.0 0.0097 15.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 RJW62083.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RJW62083.1 - 0.018 15.3 0.2 0.26 11.6 0.2 2.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RJW62083.1 - 0.022 14.5 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 RJW62083.1 - 0.026 14.1 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 RJW62083.1 - 0.04 14.1 0.9 1.2 9.5 0.9 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Dala_Dala_lig_N PF01820.21 RJW62083.1 - 0.044 14.2 0.0 0.098 13.1 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus AAA_15 PF13175.6 RJW62083.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain CH PF00307.31 RJW62084.1 - 1.7e-11 44.3 0.0 4.4e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW62084.1 - 3.8e-06 26.7 0.0 9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain ADIP PF11559.8 RJW62084.1 - 0.0079 16.3 2.0 0.0079 16.3 2.0 5.4 5 1 0 5 5 5 1 Afadin- and alpha -actinin-Binding ERM PF00769.19 RJW62084.1 - 0.0095 15.8 0.7 0.0095 15.8 0.7 4.4 2 1 1 3 3 3 1 Ezrin/radixin/moesin family Shugoshin_N PF07558.11 RJW62084.1 - 0.011 15.5 1.0 0.011 15.5 1.0 4.3 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region NPV_P10 PF05531.12 RJW62084.1 - 0.013 15.9 8.3 2.5 8.6 0.1 4.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein zf-C4H2 PF10146.9 RJW62084.1 - 0.94 9.7 25.1 0.097 13.0 5.6 4.4 3 2 0 3 3 3 0 Zinc finger-containing protein Borrelia_P83 PF05262.11 RJW62084.1 - 2.4 6.5 8.5 0.021 13.4 0.3 1.6 2 0 0 2 2 2 0 Borrelia P83/100 protein DnaJ PF00226.31 RJW62085.1 - 1.1e-28 99.2 5.9 1.3e-28 98.8 5.9 1.1 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 RJW62085.1 - 0.0049 16.8 0.3 0.0086 16.0 0.3 1.4 1 0 0 1 1 1 1 A repeated domain in UCH-protein RVT_1 PF00078.27 RJW62086.1 - 3.5e-45 154.2 0.0 6.4e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGAP PF00620.27 RJW62086.1 - 1.9e-06 27.8 0.1 5.4e-06 26.3 0.1 1.7 1 1 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 RJW62086.1 - 0.00015 21.3 0.6 0.00034 20.2 0.6 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PHD_2 PF13831.6 RJW62087.1 - 3.2e-05 23.4 6.4 3.2e-05 23.4 6.4 1.9 2 0 0 2 2 2 1 PHD-finger MBT PF02820.18 RJW62087.1 - 0.0039 17.5 0.0 0.0095 16.3 0.0 1.6 1 0 0 1 1 1 1 mbt repeat zf-C2H2 PF00096.26 RJW62087.1 - 0.0053 17.1 0.8 0.018 15.5 0.8 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type Tudor-knot PF11717.8 RJW62087.1 - 0.021 14.7 3.4 3 7.8 0.2 2.6 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Agenet PF05641.12 RJW62087.1 - 0.052 14.0 0.8 0.48 10.9 0.2 2.4 2 0 0 2 2 2 0 Agenet domain PHD PF00628.29 RJW62087.1 - 0.058 13.3 13.5 0.26 11.2 13.7 2.1 1 1 0 1 1 1 0 PHD-finger Lig_chan PF00060.26 RJW62088.1 - 0.00025 20.9 0.2 0.00032 20.6 0.2 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Pkinase PF00069.25 RJW62090.1 - 1.9e-35 122.5 0.0 1.3e-24 87.0 0.0 4.7 4 1 1 5 5 5 3 Protein kinase domain Lig_chan-Glu_bd PF10613.9 RJW62090.1 - 3.1e-24 85.4 0.1 5.7e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Pkinase_Tyr PF07714.17 RJW62090.1 - 1.3e-10 41.0 0.0 3.7e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase SBP_bac_3 PF00497.20 RJW62090.1 - 2.5e-05 23.8 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 RJW62090.1 - 4.2e-05 23.4 0.0 8.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel Kinase-like PF14531.6 RJW62090.1 - 0.0066 15.8 0.0 0.02 14.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Chordopox_A13L PF05961.11 RJW62090.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Pkinase_fungal PF17667.1 RJW62090.1 - 0.083 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 RJW62090.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Neur_chan_LBD PF02931.23 RJW62095.1 - 1.1e-57 194.9 0.5 1.9e-57 194.2 0.5 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW62095.1 - 9.2e-28 97.9 0.0 1.5e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SDP_N PF12278.8 RJW62096.1 - 0.031 14.4 0.1 0.033 14.3 0.1 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Lig_chan PF00060.26 RJW62097.1 - 2.6e-08 33.8 0.0 6.7e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RJW62097.1 - 0.0001 21.8 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 E1_dh PF00676.20 RJW62101.1 - 4.9e-111 370.5 0.0 5.7e-111 370.3 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RJW62101.1 - 0.0058 15.9 0.1 0.0098 15.1 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase LysM PF01476.20 RJW62105.1 - 7.4e-10 38.7 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 LysM domain GRAM PF02893.20 RJW62105.1 - 0.036 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 GRAM domain ERK-JNK_inhib PF15002.6 RJW62105.1 - 0.056 13.1 1.4 0.091 12.4 1.4 1.3 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor DUF4778 PF16008.5 RJW62105.1 - 0.074 13.1 3.2 0.11 12.5 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DUF3042 PF11240.8 RJW62105.1 - 0.19 11.8 0.5 0.35 10.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Med19 PF10278.9 RJW62105.1 - 0.32 10.9 6.4 0.56 10.1 6.4 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DDHD PF02862.17 RJW62105.1 - 0.4 10.8 4.2 0.83 9.8 4.2 1.4 1 0 0 1 1 1 0 DDHD domain FCP1_C PF09309.10 RJW62105.1 - 1.2 9.0 13.6 5.6 6.8 0.7 2.2 2 0 0 2 2 2 0 FCP1, C-terminal zf-C2H2 PF00096.26 RJW62107.1 - 3.4e-20 71.3 32.2 0.00013 22.2 1.0 7.9 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW62107.1 - 2.4e-18 65.6 46.8 1.7e-07 31.3 2.8 9.7 10 0 0 10 10 10 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW62107.1 - 5e-12 45.6 39.7 0.04 14.8 3.4 8.1 8 0 0 8 8 7 5 C2H2-type zinc finger zf-Di19 PF05605.12 RJW62107.1 - 7.1e-08 32.6 19.7 0.0014 18.9 1.7 4.2 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 RJW62107.1 - 1.7e-05 25.0 11.8 0.23 11.8 0.0 5.9 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW62107.1 - 0.01 16.2 13.8 3.7 8.1 0.1 5.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 RJW62107.1 - 0.014 15.0 0.2 0.014 15.0 0.2 5.6 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 RJW62107.1 - 0.046 13.7 30.2 0.38 10.8 1.8 6.0 6 0 0 6 6 6 0 C2H2-type zinc finger PI31_Prot_N PF11566.8 RJW62107.1 - 0.069 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal zf-BED PF02892.15 RJW62107.1 - 0.12 12.4 17.0 2.7 8.1 1.0 5.4 2 1 3 5 5 5 0 BED zinc finger zf-TRAF PF02176.18 RJW62107.1 - 0.14 12.9 9.3 0.098 13.4 1.5 3.2 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_12 PF18658.1 RJW62107.1 - 0.29 10.7 9.8 0.68 9.6 0.2 3.9 3 1 1 4 4 4 0 Zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 RJW62107.1 - 0.34 10.9 17.3 0.11 12.4 2.0 3.8 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 RJW62107.1 - 0.99 10.2 7.7 27 5.6 0.1 3.9 3 0 0 3 3 3 0 zinc-ribbon family Elf1 PF05129.13 RJW62107.1 - 1 9.5 12.4 1.9 8.6 1.6 4.0 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like Dyp_perox PF04261.12 RJW62108.1 - 1.7e-35 122.6 0.0 2.3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family rve PF00665.26 RJW62109.1 - 2.9e-16 59.8 0.0 5.4e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RJW62109.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain LRR_2 PF07723.13 RJW62109.1 - 3.8 8.3 8.7 14 6.5 0.3 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat Gag_p24 PF00607.20 RJW62111.1 - 1.6e-17 64.1 1.3 2.4e-17 63.5 1.3 1.2 1 0 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) Dicer_dimer PF03368.14 RJW62111.1 - 0.056 13.6 0.0 46 4.3 0.0 3.4 2 1 1 3 3 3 0 Dicer dimerisation domain DUF2617 PF10936.8 RJW62111.1 - 0.11 12.6 0.0 8.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF2617 WD40 PF00400.32 RJW62112.1 - 2.6e-18 66.0 10.9 6.5e-05 23.6 0.1 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW62112.1 - 6.7e-09 35.9 0.0 0.0056 16.9 0.0 4.5 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW62112.1 - 0.0039 15.9 0.0 0.007 15.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40_like PF17005.5 RJW62112.1 - 0.11 11.9 0.0 0.5 9.6 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain Metallophos PF00149.28 RJW62113.1 - 1e-35 124.1 1.5 1.3e-35 123.8 0.9 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RJW62113.1 - 0.00074 19.9 0.1 0.0017 18.7 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 RJW62113.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 RJW62113.1 - 0.08 13.1 0.0 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain 23S_rRNA_IVP PF05635.11 RJW62113.1 - 0.11 12.9 0.2 0.31 11.4 0.2 1.7 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein C2 PF00168.30 RJW62114.1 - 1.3e-52 176.4 0.0 2e-26 92.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.6 RJW62114.1 - 0.00085 19.2 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.6 RJW62114.1 - 0.0028 17.2 0.0 1.7 8.2 0.0 2.8 3 0 0 3 3 3 2 CEP76 C2 domain TIMP PF00965.17 RJW62115.1 - 0.031 14.1 0.1 0.077 12.8 0.0 1.6 2 0 0 2 2 2 0 Tissue inhibitor of metalloproteinase E1_DerP2_DerF2 PF02221.15 RJW62115.1 - 0.082 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 ML domain N2227 PF07942.12 RJW62116.1 - 1.7e-103 345.6 0.0 2.7e-103 344.9 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 RJW62116.1 - 2.9e-05 24.6 0.0 0.0002 21.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RJW62116.1 - 0.008 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW62116.1 - 0.016 15.9 0.0 0.41 11.4 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Ubie_methyltran PF01209.18 RJW62116.1 - 0.037 13.3 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SKA2 PF16740.5 RJW62116.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Methyltransf_12 PF08242.12 RJW62116.1 - 0.13 13.1 0.0 0.57 10.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Cas1_AcylT PF07779.12 RJW62117.1 - 4.5e-104 349.0 29.6 2.3e-65 221.4 16.1 2.0 2 0 0 2 2 2 2 10 TM Acyl Transferase domain found in Cas1p Lectin_N PF03954.14 RJW62117.1 - 0.12 12.1 0.1 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF2207 PF09972.9 RJW62117.1 - 0.12 11.1 0.6 0.31 9.7 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Serpin PF00079.20 RJW62119.1 - 1.8e-77 261.2 0.0 2e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Sec7 PF01369.20 RJW62121.1 - 2.6e-39 134.8 0.1 4.3e-39 134.1 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain Aminotran_1_2 PF00155.21 RJW62122.1 - 2.6e-82 276.9 0.0 3.1e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RVT_1 PF00078.27 RJW62123.1 - 0.0012 18.4 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DCB PF16213.5 RJW62124.1 - 0.002 17.8 0.2 0.0041 16.8 0.2 1.5 1 1 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Nucleoporin_N PF08801.11 RJW62126.1 - 5.3e-50 170.4 0.0 8.2e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like TSP_1 PF00090.19 RJW62127.1 - 1.3e-08 34.9 7.8 5.7e-08 32.8 7.8 2.2 1 0 0 1 1 1 1 Thrombospondin type 1 domain EGF PF00008.27 RJW62127.1 - 0.03 14.6 45.9 0.14 12.5 6.7 6.5 4 1 1 5 5 5 0 EGF-like domain hEGF PF12661.7 RJW62127.1 - 0.031 14.9 3.6 0.031 14.9 3.6 7.1 5 3 0 5 5 5 0 Human growth factor-like EGF Cg6151-P PF10233.9 RJW62127.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Ank_2 PF12796.7 RJW62128.1 - 5.1e-21 75.1 0.4 2.5e-10 40.8 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW62128.1 - 2.2e-19 69.2 1.2 3e-07 30.6 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW62128.1 - 2.6e-15 56.6 2.9 9e-06 26.1 0.1 4.6 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW62128.1 - 7.9e-15 53.5 3.3 0.0044 17.4 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 RJW62128.1 - 3.2e-13 49.5 3.2 0.0023 18.3 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Roc PF08477.13 RJW62128.1 - 8.5e-06 26.0 0.2 0.0012 19.0 0.0 2.6 1 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 RJW62128.1 - 2.1e-05 24.4 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Death PF00531.22 RJW62128.1 - 0.00015 21.9 0.0 0.00045 20.3 0.0 1.9 1 0 0 1 1 1 1 Death domain Ras PF00071.22 RJW62128.1 - 0.0059 16.2 0.0 0.071 12.7 0.0 2.3 1 1 0 1 1 1 1 Ras family DUF5333 PF17267.2 RJW62128.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5333) RRM_1 PF00076.22 RJW62129.1 - 4.6e-34 116.1 0.2 6e-11 42.0 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW62129.1 - 1.1e-08 34.7 0.1 0.0011 18.5 0.1 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 RJW62129.1 - 4.5e-06 26.6 0.0 0.00071 19.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 RJW62129.1 - 0.00062 19.6 0.1 0.2 11.6 0.0 3.1 3 1 0 3 3 3 1 Occluded RNA-recognition motif K_channel_TID PF07941.11 RJW62129.1 - 0.0061 17.0 5.6 0.0061 17.0 5.6 1.7 2 0 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain DUF2122 PF09895.9 RJW62129.1 - 0.1 13.0 0.0 13 6.2 0.0 3.1 3 0 0 3 3 3 0 RecB-family nuclease (DUF2122) DUF3504 PF12012.8 RJW62130.1 - 3.5e-64 215.7 0.0 1.5e-40 138.8 0.0 4.3 4 0 0 4 4 4 3 Domain of unknown function (DUF3504) Pkinase_Tyr PF07714.17 RJW62131.1 - 9e-72 241.5 0.0 1.3e-71 240.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW62131.1 - 3.1e-42 144.8 0.0 5.4e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 RJW62131.1 - 3.9e-18 65.7 0.2 6.9e-18 64.9 0.2 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Kinase-like PF14531.6 RJW62131.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF4829 PF16111.5 RJW62131.1 - 0.054 14.3 0.2 0.18 12.6 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4829) RVT_1 PF00078.27 RJW62132.1 - 6.4e-10 38.9 0.0 6.5e-07 29.1 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bravo_FIGEY PF13882.6 RJW62133.1 - 2e-18 67.5 0.6 3.5e-18 66.7 0.6 1.4 1 0 0 1 1 1 1 Bravo-like intracellular region RPN6_N PF18055.1 RJW62134.1 - 8e-34 116.5 0.1 1.6e-33 115.5 0.1 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 RJW62134.1 - 1.5e-12 47.9 0.0 3.6e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 RJW62134.1 - 0.00074 19.4 0.2 2.5 8.5 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW62134.1 - 0.0029 17.1 0.8 0.0046 16.4 0.8 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 RJW62134.1 - 0.0042 17.3 5.1 0.0093 16.2 2.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW62134.1 - 0.0047 17.6 0.9 0.018 15.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN6_C_helix PF18503.1 RJW62134.1 - 0.065 13.0 0.0 0.22 11.3 0.0 2.0 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain Arf PF00025.21 RJW62136.1 - 1.1e-57 194.3 0.1 1.2e-57 194.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RJW62136.1 - 1.3e-12 47.9 0.1 1.8e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RJW62136.1 - 3.3e-11 43.1 0.0 3.7e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 RJW62136.1 - 1.4e-07 31.6 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RJW62136.1 - 3.6e-07 29.8 0.0 4.4e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RJW62136.1 - 1.2e-06 28.0 0.4 0.00043 19.6 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RJW62136.1 - 6.2e-05 22.5 0.0 8.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RJW62136.1 - 0.0069 15.9 0.0 0.032 13.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RJW62136.1 - 0.13 11.8 0.4 0.85 9.1 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Tropomodulin PF03250.14 RJW62137.1 - 2.3e-58 196.3 4.0 2.3e-58 196.3 4.0 1.7 2 0 0 2 2 2 1 Tropomodulin Nif11 PF07862.11 RJW62137.1 - 0.069 13.5 0.9 6.7 7.1 0.1 2.8 2 0 0 2 2 2 0 Nif11 domain Raco_middle PF17651.1 RJW62137.1 - 0.15 11.7 0.7 0.29 10.8 0.7 1.5 1 0 0 1 1 1 0 RACo middle region LRR_6 PF13516.6 RJW62137.1 - 3.3 8.0 7.2 2.7 8.3 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich repeat SET PF00856.28 RJW62138.1 - 4.4e-22 79.3 3.1 5.4e-21 75.7 0.7 2.7 2 1 0 2 2 2 1 SET domain CT47 PF15623.6 RJW62138.1 - 0.016 15.1 0.2 0.02 14.7 0.2 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Myc_N PF01056.18 RJW62138.1 - 0.022 14.7 0.6 0.031 14.2 0.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.6 RJW62138.1 - 0.081 13.3 2.9 0.14 12.6 2.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zn_Tnp_IS1 PF03811.13 RJW62139.1 - 4.3 7.1 7.7 7.8 6.3 0.2 3.1 2 1 1 3 3 3 0 InsA N-terminal domain RHH_1 PF01402.21 RJW62140.1 - 0.57 10.2 3.0 1.5 8.9 0.1 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Cas9_Topo PF17894.1 RJW62141.1 - 0.027 14.5 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Cation_efflux PF01545.21 RJW62143.1 - 3.8e-43 147.6 5.1 3.8e-43 147.6 5.1 1.5 2 0 0 2 2 2 1 Cation efflux family zf-C2H2 PF00096.26 RJW62146.1 - 5.3e-13 48.6 16.3 0.00037 20.8 0.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW62146.1 - 6.2e-11 42.2 17.4 0.00058 20.5 0.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW62146.1 - 3.2e-10 39.9 14.3 1.5e-06 28.3 0.4 4.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW62146.1 - 7.8e-05 22.8 7.2 1.5 9.2 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW62146.1 - 0.00078 19.8 8.5 1.3 9.5 0.9 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 RJW62146.1 - 0.0032 17.3 0.2 0.0032 17.3 0.2 3.6 4 0 0 4 4 4 1 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 RJW62146.1 - 0.015 16.0 2.8 0.015 16.0 2.8 2.3 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats FYVE PF01363.21 RJW62146.1 - 0.022 14.9 7.4 0.049 13.8 0.5 2.6 1 1 1 2 2 2 0 FYVE zinc finger zf-Di19 PF05605.12 RJW62146.1 - 0.03 14.6 10.0 0.14 12.5 4.0 2.9 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RJW62146.1 - 0.039 14.0 10.6 1.8 8.7 0.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger PyrI_C PF02748.15 RJW62146.1 - 0.04 13.8 0.2 2 8.4 0.0 2.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_C2H2_ZHX PF18387.1 RJW62146.1 - 0.067 12.8 3.6 5.2 6.8 0.4 2.8 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn-C2H2_12 PF18112.1 RJW62146.1 - 0.087 13.3 0.2 0.087 13.3 0.2 2.8 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_11 PF16622.5 RJW62146.1 - 0.11 12.3 8.0 1.7 8.5 0.0 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 RJW62146.1 - 0.13 12.4 6.6 1.6 8.9 1.1 3.4 2 1 0 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 RJW62146.1 - 0.24 11.2 4.0 4.7 7.0 0.1 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-MYST PF17772.1 RJW62146.1 - 0.24 11.1 5.8 0.41 10.3 0.2 3.1 2 1 1 3 3 3 0 MYST family zinc finger domain Lar_restr_allev PF14354.6 RJW62146.1 - 0.29 11.5 0.2 0.29 11.5 0.2 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-AN1 PF01428.16 RJW62146.1 - 0.56 10.4 6.4 12 6.2 0.2 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger Rpr2 PF04032.16 RJW62146.1 - 0.96 9.8 5.6 7.2 7.0 1.3 3.3 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NOB1_Zn_bind PF08772.11 RJW62146.1 - 1.2 9.4 4.9 0.64 10.2 1.3 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf_UBZ PF18439.1 RJW62146.1 - 1.6 8.4 5.4 6.3 6.5 0.4 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 RJW62146.1 - 2.2 8.4 6.6 6.2 6.9 5.0 2.6 1 1 1 2 2 2 0 Double zinc ribbon zf-CHCC PF10276.9 RJW62146.1 - 2.8 8.1 6.9 14 5.8 0.2 3.7 4 0 0 4 4 3 0 Zinc-finger domain zf-C2H2_2 PF12756.7 RJW62146.1 - 3.1 8.2 13.1 0.46 10.8 0.2 3.9 3 1 2 5 5 4 0 C2H2 type zinc-finger (2 copies) zf_C2H2_6 PF18450.1 RJW62146.1 - 6.5 6.6 10.8 3 7.6 0.8 3.1 3 0 0 3 3 3 0 Zinc Finger domain DUF2256 PF10013.9 RJW62146.1 - 8.8 6.5 6.4 9.8 6.4 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4078 PF13300.6 RJW62147.1 - 3.2e-19 69.0 5.0 3.2e-19 69.0 5.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) RRM_Rrp7 PF17799.1 RJW62147.1 - 0.08 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain RVT_1 PF00078.27 RJW62148.1 - 1.6e-46 158.6 0.2 3.8e-46 157.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RanBP PF00641.18 RJW62148.1 - 0.0022 17.3 10.6 0.0022 17.3 10.6 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RecR PF02132.15 RJW62148.1 - 1 9.0 14.2 0.36 10.4 4.2 2.6 2 0 0 2 2 2 0 RecR protein DZR PF12773.7 RJW62148.1 - 5 7.2 11.7 16 5.6 2.4 1.9 1 1 1 2 2 2 0 Double zinc ribbon Malic_M PF03949.15 RJW62150.1 - 5.5e-78 261.8 0.0 7.8e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 RJW62150.1 - 6e-73 244.5 0.0 8.8e-73 244.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Integrase_Zn PF02022.19 RJW62150.1 - 0.15 12.1 0.1 0.38 10.8 0.1 1.7 1 0 0 1 1 1 0 Integrase Zinc binding domain GST_N_2 PF13409.6 RJW62153.1 - 0.07 13.4 0.0 0.073 13.4 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain C2 PF00168.30 RJW62154.1 - 1e-09 38.6 0.0 2.6e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain FYVE_2 PF02318.16 RJW62154.1 - 0.0045 17.2 5.6 0.0045 17.2 5.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-piccolo PF05715.13 RJW62154.1 - 0.0064 16.6 9.2 0.013 15.6 9.2 1.5 1 0 0 1 1 1 1 Piccolo Zn-finger CN_hydrolase PF00795.22 RJW62155.1 - 2.5e-55 187.7 0.0 2.8e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Meis_PKNOX_N PF16493.5 RJW62156.1 - 6.1e-24 84.2 1.8 9.8e-24 83.5 0.6 1.9 2 0 0 2 2 2 1 N-terminal of Homeobox Meis and PKNOX1 KNOX1 PF03790.13 RJW62156.1 - 0.041 13.6 0.1 0.071 12.8 0.1 1.4 1 0 0 1 1 1 0 KNOX1 domain FAM60A PF15396.6 RJW62158.1 - 2.5e-28 99.5 6.6 5.2e-28 98.5 6.6 1.5 1 0 0 1 1 1 1 Protein Family FAM60A SOCS_box PF07525.16 RJW62160.1 - 4e-05 23.9 4.8 0.00011 22.5 4.8 1.8 1 0 0 1 1 1 1 SOCS box CCDC24 PF15669.5 RJW62160.1 - 0.27 11.1 0.1 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family zf-H2C2_2 PF13465.6 RJW62162.1 - 9.5e-20 70.1 40.3 1.4e-07 31.6 3.6 8.1 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.26 RJW62162.1 - 5.1e-15 55.0 48.9 0.00029 21.1 0.7 7.5 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-Di19 PF05605.12 RJW62162.1 - 7.6e-10 38.9 22.2 0.00012 22.3 1.3 4.0 3 1 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 RJW62162.1 - 2.1e-09 37.4 48.7 0.082 13.8 0.4 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW62162.1 - 5.4e-05 23.4 18.7 0.48 10.8 0.5 6.0 6 1 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW62162.1 - 7e-05 22.7 21.1 0.064 13.3 0.0 5.9 5 0 0 5 5 5 2 C2H2-type zinc finger Rad50_zn_hook PF04423.14 RJW62162.1 - 0.051 13.4 4.4 0.4 10.6 0.2 2.8 1 1 1 2 2 2 0 Rad50 zinc hook motif zf-met PF12874.7 RJW62162.1 - 0.053 13.9 23.1 0.6 10.6 0.1 6.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type DUF2225 PF09986.9 RJW62162.1 - 0.12 12.1 4.0 0.88 9.3 1.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) HypA PF01155.19 RJW62162.1 - 0.64 10.1 10.1 0.5 10.4 0.9 3.2 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_11 PF16622.5 RJW62162.1 - 1.5 8.6 17.1 4.4 7.2 0.0 4.6 4 0 0 4 4 4 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 RJW62162.1 - 2.2 9.1 12.5 17 6.2 0.1 4.0 3 0 0 3 3 3 0 zinc-ribbon family zf-C2H2_12 PF18658.1 RJW62162.1 - 7.4 6.2 17.8 0.93 9.1 2.3 4.7 3 2 2 5 5 5 0 Zinc-finger C2H2-type PARP PF00644.20 RJW62163.1 - 2.8e-55 186.9 0.0 5e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 RJW62163.1 - 3.6e-47 159.9 1.3 6.9e-47 159.0 1.3 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 RJW62163.1 - 5e-21 74.5 1.6 2.2e-20 72.5 0.5 2.4 1 1 1 2 2 2 1 WGR domain PADR1 PF08063.12 RJW62163.1 - 3.7e-20 71.5 1.8 5.3e-20 70.9 0.2 2.2 2 0 0 2 2 2 1 PADR1 (NUC008) domain zf-PARP PF00645.18 RJW62163.1 - 6.9e-11 42.9 5.1 6.1e-06 27.0 0.1 3.7 2 1 1 3 3 3 3 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF4795 PF16043.5 RJW62164.1 - 2.5e-36 125.2 0.2 3.2e-36 124.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Syntaxin-6_N PF09177.11 RJW62164.1 - 0.037 14.6 0.6 0.088 13.4 0.6 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal BMFP PF04380.13 RJW62164.1 - 0.057 13.9 3.1 0.2 12.1 1.3 2.3 1 1 1 2 2 2 0 Membrane fusogenic activity BAR PF03114.18 RJW62164.1 - 0.36 10.4 4.5 0.83 9.3 3.6 1.9 1 1 2 3 3 3 0 BAR domain DUF1451 PF07295.11 RJW62164.1 - 9.7 6.2 6.3 2.7 8.0 0.4 2.5 1 1 2 3 3 3 0 Zinc-ribbon containing domain DUF3715 PF12509.8 RJW62165.1 - 2.4e-36 125.0 0.2 2.1e-35 121.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3715) SAP18 PF06487.12 RJW62166.1 - 9.6e-38 129.5 0.0 1.7e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) AFT PF08731.11 RJW62166.1 - 0.0069 16.8 1.4 0.012 16.0 1.4 1.3 1 0 0 1 1 1 1 Transcription factor AFT DUF2970 PF11174.8 RJW62168.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) ADK PF00406.22 RJW62170.1 - 9.4e-39 132.9 0.0 1.2e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RJW62170.1 - 2.1e-29 102.7 0.0 2.6e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RJW62170.1 - 1.9e-07 31.7 0.0 2.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RJW62170.1 - 0.00039 20.6 0.0 0.00084 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RJW62170.1 - 0.0073 15.6 0.0 0.0086 15.4 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 RJW62170.1 - 0.062 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 RJW62170.1 - 0.066 12.9 0.3 2.3 7.9 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase CoaE PF01121.20 RJW62170.1 - 0.092 12.4 0.1 9.8 5.8 0.1 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase NB-ARC PF00931.22 RJW62170.1 - 0.12 11.6 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 RJW62170.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 RJW62170.1 - 0.18 11.5 0.1 0.37 10.5 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase zf-H2C2_2 PF13465.6 RJW62171.1 - 1.6e-11 44.0 15.7 1.1e-05 25.6 0.0 4.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW62171.1 - 2.1e-05 25.0 27.7 0.02 15.7 0.3 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW62171.1 - 0.00013 22.2 24.2 0.0016 18.8 0.3 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type DZR PF12773.7 RJW62171.1 - 0.2 11.7 0.1 0.2 11.7 0.1 3.8 3 1 0 3 3 3 0 Double zinc ribbon zf-C2H2_6 PF13912.6 RJW62171.1 - 0.89 9.6 15.5 4.8 7.3 2.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 RJW62171.1 - 0.96 9.1 6.1 13 5.5 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 RJW62171.1 - 4 7.3 5.2 5 7.1 0.0 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 RJW62171.1 - 4.1 7.6 12.7 12 6.1 0.0 3.8 3 1 1 4 4 4 0 Zinc ribbon domain LRR_8 PF13855.6 RJW62172.1 - 2.6e-52 174.4 46.6 2.6e-09 36.7 5.6 8.3 5 3 3 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 RJW62172.1 - 2.1e-33 113.8 56.3 7e-06 26.3 0.2 10.5 6 3 5 12 12 12 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW62172.1 - 1.4e-11 44.2 27.1 0.014 15.0 1.4 6.3 4 2 2 6 6 6 5 Leucine-rich repeat LRR_6 PF13516.6 RJW62172.1 - 4.4e-08 32.5 56.1 0.041 13.9 0.2 14.5 16 0 0 16 16 16 5 Leucine Rich repeat LRR_1 PF00560.33 RJW62172.1 - 5e-08 32.4 47.9 1.1 10.0 0.1 14.7 16 2 0 16 16 16 3 Leucine Rich Repeat LRR_5 PF13306.6 RJW62172.1 - 0.002 18.1 0.0 3.3 7.7 0.0 4.1 4 1 0 4 4 4 1 BspA type Leucine rich repeat region (6 copies) gag_pre-integrs PF13976.6 RJW62172.1 - 0.046 13.6 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 GAG-pre-integrase domain VHL PF01847.16 RJW62173.1 - 0.13 12.2 0.0 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 VHL beta domain HlyIII PF03006.20 RJW62176.1 - 8e-20 71.5 27.0 9.6e-20 71.3 27.0 1.0 1 0 0 1 1 1 1 Haemolysin-III related SLC3A2_N PF16028.5 RJW62176.1 - 0.029 13.9 3.6 0.082 12.5 3.6 1.9 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus OB_NTP_bind PF07717.16 RJW62178.1 - 0.13 12.6 1.8 2.4 8.6 0.3 2.6 2 0 0 2 2 2 0 Oligonucleotide/oligosaccharide-binding (OB)-fold 2OG-FeII_Oxy_2 PF13532.6 RJW62180.1 - 0.00046 20.4 0.0 0.00073 19.8 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PDEase_I PF00233.19 RJW62181.1 - 3.8e-34 118.4 6.8 8.1e-34 117.4 6.8 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 RJW62181.1 - 6.9e-21 75.1 0.9 1.3e-16 61.3 0.2 2.5 2 0 0 2 2 2 2 Phosphodiesterase 4 upstream conserved regions (UCR) COQ7 PF03232.13 RJW62181.1 - 2.3 8.0 3.7 1.4 8.7 1.1 1.9 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 PH PF00169.29 RJW62183.1 - 1.1e-05 25.8 0.0 0.067 13.7 0.0 2.6 2 0 0 2 2 2 2 PH domain Dynein_light PF01221.18 RJW62187.1 - 2.5e-16 59.7 0.0 5e-16 58.8 0.0 1.5 2 0 0 2 2 2 1 Dynein light chain type 1 Sec7 PF01369.20 RJW62189.1 - 2.8e-17 63.0 0.0 4.2e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 RJW62189.1 - 1e-06 28.8 0.1 6.6e-06 26.1 0.0 2.0 1 1 1 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Snf7 PF03357.21 RJW62192.1 - 3.8e-40 137.3 13.6 4.8e-40 137.0 13.6 1.1 1 0 0 1 1 1 1 Snf7 YtxH PF12732.7 RJW62192.1 - 1.7 9.2 6.7 61 4.3 6.7 2.5 1 1 0 1 1 1 0 YtxH-like protein DUF963 PF06131.11 RJW62196.1 - 0.084 12.3 0.8 0.19 11.2 0.8 1.6 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Amidinotransf PF02274.17 RJW62196.1 - 0.089 11.9 0.0 0.38 9.8 0.0 2.0 3 0 0 3 3 3 0 Amidinotransferase SQS_PSY PF00494.19 RJW62197.1 - 9.9e-30 103.9 0.6 1.1e-29 103.7 0.6 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Ribosomal_L16 PF00252.18 RJW62200.1 - 1.3e-43 148.2 0.1 1.7e-43 147.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Lebercilin PF15619.6 RJW62201.1 - 9.4e-19 67.8 35.7 9.4e-19 67.8 35.7 2.4 3 0 0 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease DUF2180 PF09947.9 RJW62201.1 - 0.029 14.3 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Ssu72 PF04722.13 RJW62201.1 - 0.096 12.2 2.9 0.19 11.3 2.9 1.4 1 0 0 1 1 1 0 Ssu72-like protein DUF5595 PF18077.1 RJW62201.1 - 2.7 8.1 5.1 2.3 8.4 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Spc7 PF08317.11 RJW62201.1 - 8.6 5.1 29.4 3.3 6.5 11.5 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 RJW62201.1 - 8.9 6.1 19.5 15 5.3 8.4 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Homeodomain PF00046.29 RJW62203.1 - 2e-07 30.8 0.3 4.3e-07 29.7 0.3 1.6 1 0 0 1 1 1 1 Homeodomain PNPase_C PF12111.8 RJW62203.1 - 0.16 11.5 0.4 0.35 10.3 0.4 1.6 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal zf-C4 PF00105.18 RJW62204.1 - 1.2e-28 99.3 15.6 3e-28 98.1 15.6 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW62204.1 - 1.1e-09 38.2 0.0 3e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MFS_1 PF07690.16 RJW62205.1 - 8.5e-32 110.4 19.1 1.1e-27 96.9 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 RJW62205.1 - 0.0017 16.8 0.2 0.42 8.8 0.0 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF5518 PF17647.1 RJW62205.1 - 0.28 11.3 21.4 0.19 11.9 2.6 3.4 3 1 0 3 3 3 0 Family of unknown function (DUF5518) NDK PF00334.19 RJW62206.1 - 2.6e-16 59.9 0.0 3.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PHD PF00628.29 RJW62208.1 - 1.6e-09 37.5 58.2 2.5e-05 24.1 7.1 7.7 6 2 1 7 7 7 4 PHD-finger UAE_UbL PF14732.6 RJW62210.1 - 7e-20 71.4 0.0 1.5e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ThiF PF00899.21 RJW62210.1 - 1.9e-05 24.1 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 RJW62210.1 - 0.0039 17.1 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site zf-C2H2_4 PF13894.6 RJW62211.1 - 5.2e-14 51.8 50.6 0.0074 17.0 0.4 8.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW62211.1 - 1.8e-09 37.6 52.8 0.0042 17.5 2.9 6.9 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-met PF12874.7 RJW62211.1 - 1.7e-06 28.2 18.0 0.14 12.6 0.4 6.8 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-BED PF02892.15 RJW62211.1 - 0.00023 21.1 0.5 0.00023 21.1 0.5 6.2 3 2 2 5 5 5 2 BED zinc finger zf-C2H2_jaz PF12171.8 RJW62211.1 - 0.00083 19.6 19.8 0.36 11.2 0.1 6.4 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 RJW62211.1 - 0.002 18.0 3.5 0.002 18.0 3.5 3.5 3 0 0 3 3 3 1 SprT-like zinc ribbon domain zf-C2H2_6 PF13912.6 RJW62211.1 - 0.021 14.8 42.0 0.07 13.1 1.2 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RJW62211.1 - 1.4 9.3 27.2 15 6.0 10.8 5.3 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 RJW62211.1 - 8.5 6.5 18.8 0.19 11.7 1.2 4.1 4 1 0 4 4 4 0 Adenylate kinase, active site lid LRR_9 PF14580.6 RJW62212.1 - 4e-05 23.2 0.0 8.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat fn3 PF00041.21 RJW62213.1 - 2e-32 111.4 24.1 3.3e-05 24.1 0.2 10.6 10 0 0 10 10 10 7 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW62213.1 - 0.00017 22.1 23.1 0.3 11.7 0.0 6.8 6 2 0 6 6 6 3 Purple acid Phosphatase, N-terminal domain DUF2567 PF10821.8 RJW62213.1 - 0.0073 16.4 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2567) Interfer-bind PF09294.10 RJW62213.1 - 0.083 13.2 7.3 6.9 7.0 0.2 5.4 6 1 1 7 7 7 0 Interferon-alpha/beta receptor, fibronectin type III BAR PF03114.18 RJW62216.1 - 9.4e-26 90.9 0.5 1.4e-25 90.3 0.5 1.3 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 RJW62216.1 - 5.4e-14 51.8 0.0 9.9e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RJW62216.1 - 9.7e-14 50.7 0.0 1.7e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain BAR_2 PF10455.9 RJW62216.1 - 7.8e-12 44.9 0.2 9.4e-12 44.7 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_2 PF07653.17 RJW62216.1 - 2.5e-11 43.1 0.0 4.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 RJW62216.1 - 0.0047 16.7 4.4 0.014 15.2 4.4 1.7 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 RJW62216.1 - 0.037 13.6 0.4 0.075 12.6 0.3 1.5 1 1 0 1 1 1 0 Arfaptin-like domain UPF0242 PF06785.11 RJW62216.1 - 0.6 10.2 4.0 0.93 9.6 4.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 RJW62216.1 - 2.3 7.7 5.4 7.8 6.0 5.3 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit RVT_1 PF00078.27 RJW62217.1 - 2.9e-09 36.8 0.0 1.3e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 RJW62219.1 - 1.1e-07 31.6 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pro_isomerase PF00160.21 RJW62220.1 - 9.7e-52 175.4 0.0 1.3e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RVT_1 PF00078.27 RJW62221.1 - 0.03 13.9 0.0 0.087 12.3 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Claudin_2 PF13903.6 RJW62221.1 - 0.6 9.8 5.1 1.1 9.0 5.1 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3509 PF12021.8 RJW62222.1 - 0.0036 17.0 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) Homeodomain PF00046.29 RJW62223.1 - 4e-20 71.4 6.4 4e-20 71.4 6.4 1.9 2 0 0 2 2 2 1 Homeodomain EPO_TPO PF00758.18 RJW62223.1 - 0.064 13.3 0.6 0.13 12.3 0.6 1.4 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin CAP PF00188.26 RJW62224.1 - 1.2e-25 90.8 0.1 3.5e-12 47.3 0.1 3.6 2 2 0 2 2 2 2 Cysteine-rich secretory protein family zf-CRD PF17979.1 RJW62224.1 - 0.095 12.8 1.8 4.2 7.5 0.1 2.5 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Med25_NR-box PF11244.8 RJW62224.1 - 0.18 12.2 1.0 8 7.0 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing HSP70 PF00012.20 RJW62228.1 - 2.6e-249 828.4 13.8 6.5e-249 827.1 13.8 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RJW62228.1 - 3.5e-16 59.0 0.3 7.7e-15 54.5 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 RJW62228.1 - 0.0025 18.2 0.1 3 8.3 0.0 2.8 2 0 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.16 RJW62228.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4845 PF16137.5 RJW62228.1 - 0.1 13.5 0.0 0.44 11.4 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4845) PIN_8 PF18476.1 RJW62228.1 - 0.55 10.1 5.8 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 PIN like domain Mago_nashi PF02792.14 RJW62229.1 - 2.5e-35 121.7 0.0 4.2e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Mago nashi protein RVT_1 PF00078.27 RJW62229.1 - 0.0036 16.8 0.0 0.0098 15.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rep_fac_C PF08542.11 RJW62230.1 - 2.7e-23 82.2 0.0 1e-22 80.3 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 RJW62230.1 - 5e-13 49.2 0.1 7.3e-11 42.1 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 RJW62230.1 - 1.6e-12 48.0 0.0 2.7e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 RJW62230.1 - 3.1e-07 30.4 0.0 5.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 RJW62230.1 - 9.7e-07 28.9 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW62230.1 - 1e-05 25.8 0.2 0.023 15.0 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 RJW62230.1 - 1.1e-05 25.9 0.0 0.0013 19.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 RJW62230.1 - 1.7e-05 24.8 0.0 5.4e-05 23.2 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_11 PF13086.6 RJW62230.1 - 0.00024 21.0 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RJW62230.1 - 0.00033 20.4 0.0 0.00085 19.1 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RJW62230.1 - 0.00055 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 RJW62230.1 - 0.00061 20.1 0.1 0.0016 18.7 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain MeaB PF03308.16 RJW62230.1 - 0.0016 17.5 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 RJW62230.1 - 0.0017 18.7 0.2 0.0078 16.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RJW62230.1 - 0.0018 18.8 0.0 0.0056 17.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 RJW62230.1 - 0.002 18.7 0.0 0.0071 16.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RJW62230.1 - 0.0024 17.6 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RJW62230.1 - 0.0028 17.1 0.1 0.03 13.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 RJW62230.1 - 0.0081 15.8 0.1 0.018 14.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 RJW62230.1 - 0.02 14.6 0.5 1.4 8.6 0.0 2.8 1 1 2 3 3 3 0 DEAD/DEAH box helicase NTPase_1 PF03266.15 RJW62230.1 - 0.022 14.7 0.2 0.14 12.1 0.0 2.1 1 1 1 2 2 2 0 NTPase AAA_30 PF13604.6 RJW62230.1 - 0.022 14.5 0.1 0.061 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 RJW62230.1 - 0.023 14.1 0.0 8 5.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_3 PF07726.11 RJW62230.1 - 0.024 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RJW62230.1 - 0.032 14.6 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 RNA helicase MipZ PF09140.11 RJW62230.1 - 0.046 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ AAA_23 PF13476.6 RJW62230.1 - 0.062 13.8 0.0 0.095 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RJW62230.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RJW62230.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 RJW62230.1 - 0.09 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain ResIII PF04851.15 RJW62230.1 - 0.12 12.4 0.0 2.9 7.9 0.0 2.6 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit PRK PF00485.18 RJW62230.1 - 0.14 11.9 0.0 9 6.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DNA_pol3_delta PF06144.13 RJW62230.1 - 0.18 11.6 0.0 0.43 10.3 0.0 1.6 2 0 0 2 2 1 0 DNA polymerase III, delta subunit tRNA-synt_1g PF09334.11 RJW62233.1 - 2.2e-18 66.2 0.0 2.7e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 RJW62233.1 - 2.2e-08 34.2 0.0 2.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA FAM76 PF16046.5 RJW62235.1 - 0.0035 16.8 2.8 0.0035 16.8 2.8 2.4 3 0 0 3 3 3 1 FAM76 protein DLP_helical PF18709.1 RJW62235.1 - 0.018 14.3 0.2 0.018 14.3 0.2 2.6 2 1 0 2 2 2 0 Dynamin-like helical domain TACC_C PF05010.14 RJW62235.1 - 0.03 14.1 16.6 0.051 13.4 16.6 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1722 PF08349.11 RJW62235.1 - 0.41 10.9 2.6 0.77 10.1 1.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1722) DUF1729 PF08354.10 RJW62235.1 - 0.65 8.8 7.4 0.99 8.2 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) NYD-SP28 PF14772.6 RJW62235.1 - 1.9 8.6 17.4 0.022 14.8 3.6 2.6 1 1 1 2 2 2 0 Sperm tail Remorin_C PF03763.13 RJW62235.1 - 4.4 7.2 11.2 6.6 6.7 0.8 2.3 2 0 0 2 2 2 0 Remorin, C-terminal region RVT_1 PF00078.27 RJW62238.1 - 2.9e-10 40.0 0.0 4.3e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2207 PF09972.9 RJW62239.1 - 0.012 14.4 0.9 0.015 14.1 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1700 PF08006.11 RJW62239.1 - 0.051 13.1 2.4 0.071 12.6 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) UPF0223 PF05256.12 RJW62239.1 - 0.054 13.8 0.1 0.093 13.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) Presenilin PF01080.17 RJW62239.1 - 2.1 7.0 11.7 0.024 13.4 4.4 1.4 2 0 0 2 2 2 0 Presenilin HSP70 PF00012.20 RJW62241.1 - 8.8e-259 859.7 6.9 1e-258 859.5 6.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RJW62241.1 - 1.7e-17 63.2 0.3 2.2e-16 59.6 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 RJW62241.1 - 0.0017 17.9 0.1 3.2 7.2 0.0 3.0 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 RJW62241.1 - 0.0027 18.1 3.0 3.2 8.2 0.1 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 RJW62241.1 - 0.016 14.5 0.5 0.063 12.5 0.1 2.3 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 RJW62241.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain La PF05383.17 RJW62244.1 - 9.4e-14 51.2 0.0 2.4e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 RJW62244.1 - 8.9e-10 38.2 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RJW62244.1 - 0.021 14.9 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif EF-hand_6 PF13405.6 RJW62245.1 - 3.4e-21 73.3 5.3 5.9e-06 25.8 0.0 4.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 RJW62245.1 - 3.2e-19 67.0 7.6 2e-05 23.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW62245.1 - 2.1e-18 66.5 5.0 3.8e-09 36.9 1.8 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW62245.1 - 4.2e-13 48.1 5.5 0.00011 21.5 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RJW62245.1 - 8.7e-13 47.9 7.4 9.3e-08 31.8 0.5 4.1 3 2 2 5 5 5 5 EF-hand domain pair Glyco_hydro_11 PF00457.17 RJW62245.1 - 0.002 17.8 0.4 0.0028 17.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 EF-hand_11 PF08976.11 RJW62245.1 - 0.029 15.2 0.0 0.047 14.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Caleosin PF05042.13 RJW62245.1 - 0.029 14.3 0.2 7.8 6.4 0.1 2.3 1 1 1 2 2 2 0 Caleosin related protein Ribosomal_L18 PF17135.4 RJW62245.1 - 0.094 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e HSP70 PF00012.20 RJW62246.1 - 1.2e-261 869.2 10.5 1.3e-261 869.0 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RJW62246.1 - 5.6e-17 61.6 0.3 1.1e-15 57.3 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 RJW62246.1 - 0.00073 19.9 0.4 2.7 8.4 0.0 3.4 3 0 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 RJW62246.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Cnd1_N PF12922.7 RJW62246.1 - 0.23 11.3 0.9 0.46 10.3 0.9 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term MULE PF10551.9 RJW62249.1 - 0.00063 20.1 0.0 0.0032 17.9 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain NHL PF01436.21 RJW62250.1 - 0.0027 17.7 0.1 5.4 7.3 0.0 4.7 5 0 0 5 5 5 1 NHL repeat HSP70 PF00012.20 RJW62251.1 - 1.5e-261 868.9 10.1 1.7e-261 868.7 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RJW62251.1 - 2.7e-17 62.6 0.3 7e-16 58.0 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 RJW62251.1 - 0.0011 19.4 2.8 1.9 9.0 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 RJW62251.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MetOD2 PF18548.1 RJW62251.1 - 0.078 13.1 0.6 0.35 11.0 0.1 2.4 2 0 0 2 2 2 0 Metanogen output domain 2 Cnd1_N PF12922.7 RJW62251.1 - 0.19 11.6 1.1 0.37 10.6 1.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Homeodomain PF00046.29 RJW62252.1 - 8.3e-21 73.6 5.8 8.3e-21 73.6 5.8 2.0 2 0 0 2 2 2 1 Homeodomain FANCL_C PF11793.8 RJW62252.1 - 0.066 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain RVT_1 PF00078.27 RJW62253.1 - 8.9e-46 156.2 0.0 1.5e-45 155.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_1 PF01344.25 RJW62254.1 - 4.7e-50 166.9 21.2 8.3e-14 50.9 0.3 6.7 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RJW62254.1 - 9.1e-27 92.4 13.8 1.5e-08 34.6 0.1 7.2 2 1 4 6 6 6 4 Kelch motif Kelch_4 PF13418.6 RJW62254.1 - 3.5e-18 65.3 9.4 2.1e-06 27.6 0.2 6.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 RJW62254.1 - 4e-18 64.6 12.5 4.2e-06 26.5 0.0 5.9 7 0 0 7 7 7 4 Kelch motif BACK PF07707.15 RJW62254.1 - 5.1e-17 61.9 0.2 9.7e-17 61.0 0.2 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 RJW62254.1 - 2.5e-13 49.9 9.6 1.3e-05 25.4 0.4 5.6 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW62254.1 - 8e-12 44.9 6.6 0.0029 17.6 0.0 5.7 6 0 0 6 6 6 4 Kelch motif EF-hand_1 PF00036.32 RJW62256.1 - 8.1e-35 115.8 11.0 7.6e-06 25.1 0.1 6.3 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 RJW62256.1 - 6.1e-32 106.8 10.5 1.8e-05 24.3 0.0 6.3 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.6 RJW62256.1 - 9.7e-28 96.4 12.2 5e-09 36.5 1.4 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW62256.1 - 1.5e-20 71.7 18.2 0.00022 20.6 0.3 6.5 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 RJW62256.1 - 2.5e-11 43.2 15.4 0.0039 17.0 0.1 6.7 7 0 0 7 7 7 3 EF-hand domain pair EF-hand_10 PF14788.6 RJW62256.1 - 3.2e-07 30.1 6.1 0.056 13.3 0.1 4.5 3 1 1 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 RJW62256.1 - 8.2e-05 22.9 2.5 7 7.0 0.1 5.3 4 2 1 5 5 5 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 RJW62256.1 - 0.00039 20.6 1.5 1.4 9.2 0.0 3.8 4 1 0 4 4 4 2 Dockerin type I domain GPHH PF16905.5 RJW62256.1 - 0.0068 16.1 0.0 1.1 9.1 0.0 3.1 4 0 0 4 4 4 1 Voltage-dependent L-type calcium channel, IQ-associated Caleosin PF05042.13 RJW62256.1 - 0.029 14.3 1.1 28 4.6 0.1 4.1 4 1 0 4 4 4 0 Caleosin related protein WWE PF02825.20 RJW62256.1 - 0.11 13.0 0.0 6 7.5 0.0 2.6 2 0 0 2 2 2 0 WWE domain DIMCO_N PF16844.5 RJW62256.1 - 0.14 12.5 0.7 10 6.5 0.1 3.1 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Septin PF00735.18 RJW62257.1 - 2.8e-54 184.3 0.4 2.8e-54 184.3 0.4 1.8 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.27 RJW62257.1 - 0.25 10.9 8.2 0.9 9.0 8.2 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Peptidase_S49 PF01343.18 RJW62257.1 - 0.25 11.3 3.3 0.46 10.4 3.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 Atg14 PF10186.9 RJW62257.1 - 0.36 9.9 14.1 0.62 9.1 14.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 RJW62258.1 - 0.27 11.3 5.4 7.3 6.6 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Pyrophosphatase PF00719.19 RJW62259.1 - 5.7e-61 205.0 0.3 8.7e-61 204.4 0.3 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase CAP PF00188.26 RJW62260.1 - 1.9e-12 48.1 1.3 5.6e-12 46.6 1.3 1.9 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CHZ PF09649.10 RJW62261.1 - 0.14 11.7 1.7 0.4 10.2 0.4 2.1 2 0 0 2 2 2 0 Histone chaperone domain CHZ tRNA-synt_1g PF09334.11 RJW62265.1 - 8.6e-114 380.3 0.3 1.1e-113 380.0 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RJW62265.1 - 1.7e-06 26.6 0.1 0.01 14.2 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) zinc-ribbons_6 PF07191.12 RJW62265.1 - 0.69 9.9 9.7 8.7 6.4 0.5 2.7 1 1 0 2 2 2 0 zinc-ribbons zf-C2HC5 PF06221.13 RJW62265.1 - 1.3 9.0 7.7 5.2 7.2 0.9 2.6 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type DZR PF12773.7 RJW62265.1 - 1.6 8.8 11.4 3.6 7.7 6.2 2.7 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 RJW62265.1 - 3.8 7.5 8.5 10 6.1 1.6 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.19 RJW62265.1 - 7.5 6.6 8.4 13 5.8 1.6 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GST_C_2 PF13410.6 RJW62266.1 - 1.3e-07 31.5 0.0 2.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RJW62266.1 - 0.00044 20.4 0.0 0.00077 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RJW62266.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_transf_22 PF03901.17 RJW62267.1 - 2.1e-60 205.1 38.1 2.9e-60 204.7 38.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HSP70 PF00012.20 RJW62268.1 - 2.1e-155 518.3 0.0 2.5e-155 518.1 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RJW62268.1 - 4.9e-16 58.4 0.1 1.3e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 RJW62268.1 - 4.7e-05 23.8 0.0 0.2 12.1 0.0 2.9 2 2 0 2 2 2 2 Cell division protein FtsA DDR PF08841.10 RJW62268.1 - 0.009 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 RJW62268.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 RJW62268.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.18 RJW62268.1 - 0.13 11.5 0.7 1.2 8.3 0.0 2.4 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF4537 PF15057.6 RJW62269.1 - 4.6e-09 36.3 0.0 1.1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) RVT_1 PF00078.27 RJW62273.1 - 0.0035 16.9 0.0 0.0075 15.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L28 PF00830.19 RJW62273.1 - 0.04 14.1 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L28 family Glyco_hydro_19 PF00182.19 RJW62274.1 - 1.3e-19 71.0 0.5 1.1e-17 64.8 0.5 2.6 1 1 0 1 1 1 1 Chitinase class I Arrestin_N PF00339.29 RJW62275.1 - 2.3e-17 63.4 0.1 9.8e-14 51.6 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RJW62275.1 - 0.00014 22.3 0.1 2.5 8.6 0.0 4.0 4 1 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 RJW62275.1 - 0.069 12.3 0.0 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Rgp1 Ank_2 PF12796.7 RJW62276.1 - 5.3e-40 135.9 0.1 9.9e-11 42.1 0.0 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 RJW62276.1 - 6.8e-21 73.7 6.3 9.3e-05 22.7 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 RJW62276.1 - 1.3e-19 70.2 4.0 0.00016 22.1 0.0 7.5 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW62276.1 - 5.7e-16 57.0 6.2 0.0014 19.0 0.0 8.2 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 RJW62276.1 - 1.1e-12 47.9 5.3 0.0013 19.0 0.0 6.1 3 3 4 8 8 8 4 Ankyrin repeats (many copies) CAP PF00188.26 RJW62277.1 - 2.1e-21 77.1 6.2 1.8e-10 41.8 1.8 3.7 2 2 0 2 2 2 2 Cysteine-rich secretory protein family VWA_3 PF13768.6 RJW62278.1 - 8.4e-13 48.5 0.1 3.7e-11 43.2 0.0 3.0 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 RJW62278.1 - 3.8e-08 33.8 0.0 7.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RJW62278.1 - 2.6e-06 28.0 0.0 6.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain HSP70 PF00012.20 RJW62279.1 - 3.9e-264 877.4 11.9 4.5e-264 877.2 11.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RJW62279.1 - 1.3e-16 60.3 0.7 5.1e-15 55.1 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 RJW62279.1 - 0.0038 17.0 0.0 0.0097 15.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 RJW62279.1 - 0.0087 15.1 0.3 0.075 12.0 0.2 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain DUF1464 PF07318.12 RJW62279.1 - 0.012 14.8 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) FtsA PF14450.6 RJW62279.1 - 0.023 15.1 5.8 3.6 8.0 0.1 3.6 3 2 0 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 RJW62279.1 - 0.025 14.1 0.1 6.4 6.2 0.0 2.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Cnd1_N PF12922.7 RJW62279.1 - 0.2 11.5 1.7 0.4 10.5 1.7 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term MetOD2 PF18548.1 RJW62279.1 - 0.97 9.6 6.5 0.47 10.6 0.1 2.7 2 1 0 2 2 2 0 Metanogen output domain 2 PIN_8 PF18476.1 RJW62279.1 - 1.6 8.5 8.0 0.53 10.1 0.2 2.4 2 0 0 2 2 2 0 PIN like domain HEPN-like_int PF18867.1 RJW62281.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 HEPN-like integron domain 1-cysPrx_C PF10417.9 RJW62283.1 - 0.23 11.3 0.4 19 5.2 0.0 2.8 3 0 0 3 3 3 0 C-terminal domain of 1-Cys peroxiredoxin AP3D1 PF06375.11 RJW62284.1 - 2.5 8.3 12.2 4.1 7.6 0.1 2.2 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 HSP70 PF00012.20 RJW62285.1 - 3.9e-212 705.7 7.7 3.1e-114 382.4 0.4 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 RJW62285.1 - 6.7e-13 48.1 0.1 1.7e-10 40.3 0.1 2.2 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 RJW62285.1 - 0.015 15.1 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Spore_GerAC PF05504.11 RJW62285.1 - 0.16 12.2 1.5 0.73 10.0 0.0 2.6 3 0 0 3 3 3 0 Spore germination B3/ GerAC like, C-terminal RVT_1 PF00078.27 RJW62286.1 - 1.7e-34 119.3 0.0 2.4e-33 115.5 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Snf7 PF03357.21 RJW62286.1 - 1.2e-11 44.5 5.6 2.4e-11 43.5 5.6 1.4 1 0 0 1 1 1 1 Snf7 Mito_carr PF00153.27 RJW62287.1 - 1.3e-18 66.7 1.5 5e-17 61.6 0.2 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein FAS_meander PF17951.1 RJW62287.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain PrgI PF12666.7 RJW62288.1 - 0.043 14.5 0.4 2.3 9.0 0.1 2.2 2 0 0 2 2 2 0 PrgI family protein Glucosamine_iso PF01182.20 RJW62289.1 - 2.9e-19 69.9 0.0 3.6e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PhoLip_ATPase_N PF16209.5 RJW62290.1 - 2.8e-23 81.4 1.2 2.8e-23 81.4 1.2 1.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RJW62290.1 - 2.2e-07 30.9 0.0 7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RJW62290.1 - 5.6e-05 22.7 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase GIY-YIG PF01541.24 RJW62290.1 - 0.0072 16.6 0.1 0.016 15.4 0.1 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain DHHC PF01529.20 RJW62291.1 - 6.3e-34 117.0 13.1 6.3e-34 117.0 13.1 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase RVT_1 PF00078.27 RJW62294.1 - 4.3e-07 29.7 0.0 8.6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FOLN PF09289.10 RJW62295.1 - 0.33 11.2 1.0 0.72 10.1 1.0 1.6 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain CUT PF02376.15 RJW62296.1 - 2.3e-32 111.0 1.2 3.3e-32 110.5 0.3 1.7 2 0 0 2 2 2 1 CUT domain Homeodomain PF00046.29 RJW62296.1 - 5.4e-11 42.2 1.4 1.1e-10 41.2 1.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW62296.1 - 7.1e-05 22.6 0.1 0.00015 21.6 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Methyltrn_RNA_4 PF09936.9 RJW62296.1 - 0.078 12.8 0.3 0.18 11.6 0.3 1.5 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase UPF0564 PF10595.9 RJW62297.1 - 4.6e-31 108.2 35.2 4.6e-31 108.2 35.2 2.1 2 1 0 2 2 2 1 Uncharacterised protein family UPF0564 Mga PF05043.13 RJW62297.1 - 0.0048 17.4 0.9 0.0048 17.4 0.9 2.0 2 0 0 2 2 2 1 Mga helix-turn-helix domain zf-AN1 PF01428.16 RJW62298.1 - 2.4e-15 56.4 24.0 1.5e-08 34.6 10.0 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger RVT_1 PF00078.27 RJW62299.1 - 6e-10 39.0 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW62299.1 - 2.5e-08 33.8 0.3 6.2e-08 32.4 0.3 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SOCS_box PF07525.16 RJW62299.1 - 3.2e-05 24.2 5.8 3.2e-05 24.2 5.8 2.4 2 0 0 2 2 2 1 SOCS box Cadherin_2 PF08266.12 RJW62300.1 - 5.5e-09 35.7 0.2 2.1e-08 33.9 0.0 2.0 2 1 0 2 2 2 1 Cadherin-like Cadherin PF00028.17 RJW62300.1 - 0.003 17.9 0.1 0.006 17.0 0.1 1.6 1 1 0 1 1 1 1 Cadherin domain MH2 PF03166.14 RJW62301.1 - 4.1e-74 248.8 0.8 5.4e-74 248.4 0.8 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 RJW62301.1 - 1.6e-41 140.7 1.1 3.3e-41 139.7 0.3 2.0 3 0 0 3 3 3 1 MH1 domain IRF-3 PF10401.9 RJW62301.1 - 0.005 16.6 0.0 0.0082 16.0 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 RJW62301.1 - 0.11 12.5 0.6 0.23 11.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Acetyltransf_1 PF00583.25 RJW62302.1 - 2.2e-08 34.3 0.0 3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RJW62302.1 - 3.3e-06 27.0 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RJW62302.1 - 0.0003 21.2 0.0 0.00044 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RJW62302.1 - 0.00042 20.2 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RJW62302.1 - 0.0061 16.7 0.0 0.0087 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RJW62302.1 - 0.0087 16.7 0.0 0.012 16.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Bestrophin PF01062.21 RJW62303.1 - 3.4e-63 213.8 3.2 4.3e-63 213.5 3.2 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel TPR_1 PF00515.28 RJW62305.1 - 1.2e-13 50.2 6.7 0.0015 18.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW62305.1 - 8.4e-12 44.3 9.0 0.0017 18.4 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RJW62305.1 - 2.1e-07 31.1 2.1 0.0026 18.0 1.5 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RJW62305.1 - 5.5e-07 29.2 0.1 0.00032 20.3 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 RJW62305.1 - 3.5e-05 23.9 0.6 0.012 16.0 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RJW62305.1 - 0.00019 21.4 2.2 0.67 10.3 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW62305.1 - 0.0046 16.9 5.6 0.51 10.5 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RJW62305.1 - 0.17 12.6 4.6 31 5.5 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW62305.1 - 0.31 11.3 6.1 6.3 7.1 1.9 4.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RJW62305.1 - 0.37 11.7 0.1 0.37 11.7 0.1 5.3 4 1 1 5 5 4 0 Tetratricopeptide repeat CD24 PF14984.6 RJW62305.1 - 0.62 10.3 7.1 1.2 9.5 0.3 3.8 3 0 0 3 3 3 0 CD24 protein BTAD PF03704.17 RJW62305.1 - 2.3 8.7 16.8 0.23 11.9 4.3 3.7 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 RJW62305.1 - 2.3 8.4 11.0 2.3 8.4 0.4 4.6 3 1 2 5 5 4 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 RJW62307.1 - 2e-13 50.6 0.0 1.1e-12 48.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RJW62307.1 - 9.6e-10 38.5 0.1 1.7e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RJW62307.1 - 1.5e-08 35.0 0.3 6.1e-08 33.0 0.3 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RJW62307.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Sugar_tr PF00083.24 RJW62308.1 - 3.1e-29 102.2 16.3 7.4e-29 100.9 16.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW62308.1 - 1.4e-19 70.2 17.5 1.4e-19 70.2 17.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily CYYR1 PF10873.8 RJW62308.1 - 0.25 11.8 2.3 0.62 10.5 1.8 1.9 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Carb_kinase PF01256.17 RJW62309.1 - 8.8e-55 185.8 0.0 1.1e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase DUF3692 PF12469.8 RJW62309.1 - 0.063 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Asp PF00026.23 RJW62312.1 - 1.3e-34 120.1 0.0 1.4e-22 80.5 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW62312.1 - 1.8e-10 41.3 0.0 4.2e-07 30.4 0.0 3.0 1 1 2 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RJW62312.1 - 0.0089 16.6 0.0 2.6 8.7 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease Parecho_VpG PF06344.11 RJW62313.1 - 0.13 12.9 0.2 47 5.0 0.0 2.7 2 0 0 2 2 2 0 Parechovirus Genome-linked protein PhoLip_ATPase_C PF16212.5 RJW62314.1 - 7e-64 216.0 22.9 8.9e-64 215.6 22.9 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 RJW62314.1 - 5.5e-09 36.6 0.0 6.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RJW62314.1 - 0.00011 22.0 0.1 0.0012 18.6 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RJW62314.1 - 0.011 16.1 0.0 1 9.7 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase MatE PF01554.18 RJW62315.1 - 1.6e-49 167.6 25.2 6.6e-25 87.6 13.2 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 RJW62315.1 - 7.9e-09 35.7 8.9 7.9e-09 35.7 8.9 4.1 4 1 1 5 5 5 1 Polysaccharide biosynthesis C-terminal domain DUF3987 PF13148.6 RJW62319.1 - 0.0045 16.1 0.0 0.0066 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) Ribosomal_S3Ae PF01015.18 RJW62322.1 - 3.5e-80 268.4 1.5 4.1e-80 268.1 1.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family PMM PF03332.13 RJW62322.1 - 0.062 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase SCAMP PF04144.13 RJW62323.1 - 6.9e-55 186.0 12.1 8.6e-55 185.7 12.1 1.1 1 0 0 1 1 1 1 SCAMP family T6SS_VasE PF05936.12 RJW62323.1 - 0.0093 14.7 0.2 0.013 14.2 0.2 1.1 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Filamin PF00630.19 RJW62324.1 - 6e-178 579.5 10.4 7.4e-19 68.5 0.1 11.2 11 0 0 11 11 11 11 Filamin/ABP280 repeat CH PF00307.31 RJW62324.1 - 1.4e-39 134.6 0.6 1.3e-21 76.8 0.2 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Big_3_5 PF16640.5 RJW62324.1 - 1.4e-06 28.4 10.1 1.2 9.4 0.0 6.9 8 0 0 8 8 8 2 Bacterial Ig-like domain (group 3) CAMSAP_CH PF11971.8 RJW62324.1 - 4.6e-05 23.2 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain Y_Y_Y PF07495.13 RJW62324.1 - 0.0007 19.5 0.2 5.1 7.1 0.0 4.8 5 0 0 5 5 5 1 Y_Y_Y domain CH_2 PF06294.11 RJW62324.1 - 0.0026 17.8 0.1 0.2 11.8 0.0 2.3 2 0 0 2 2 2 1 CH-like domain in sperm protein DUF5060 PF16586.5 RJW62324.1 - 0.0076 16.6 0.2 1.9e+02 2.5 0.0 6.1 8 0 0 8 8 8 0 Domain of unknown function (DUF5060) Glyoxalase_4 PF13669.6 RJW62324.1 - 0.082 13.2 0.0 73 3.7 0.0 4.2 4 0 0 4 4 4 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EMP24_GP25L PF01105.24 RJW62324.1 - 0.16 11.9 0.0 2.5 8.0 0.0 2.5 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD P53_C PF11619.8 RJW62324.1 - 0.18 11.9 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain Myotub-related PF06602.14 RJW62325.1 - 3.4e-116 388.0 0.0 4.9e-116 387.5 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 RJW62325.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain HLH PF00010.26 RJW62326.1 - 2e-15 56.5 1.9 4.3e-15 55.4 1.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 RJW62326.1 - 0.16 12.4 0.5 0.38 11.2 0.5 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Mito_fiss_reg PF05308.11 RJW62327.1 - 0.00064 19.9 0.4 0.0011 19.2 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator PRKG1_interact PF15898.5 RJW62327.1 - 0.079 13.9 1.8 0.14 13.1 1.8 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Hyccin PF09790.9 RJW62328.1 - 5.6e-19 68.4 3.3 1.5e-18 67.0 3.2 1.8 1 1 0 1 1 1 1 Hyccin MMR_HSR1 PF01926.23 RJW62330.1 - 4.5e-07 29.9 0.0 2.2e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RJW62330.1 - 0.0036 16.9 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 RJW62330.1 - 0.022 14.4 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Ras family Roc PF08477.13 RJW62330.1 - 0.06 13.6 0.0 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RJW62330.1 - 0.1 12.5 0.0 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase SH3_9 PF14604.6 RJW62332.1 - 1e-15 57.3 0.3 1.9e-15 56.4 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain Abi_HHR PF07815.14 RJW62332.1 - 1.6e-15 57.0 0.0 3.4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.28 RJW62332.1 - 1.9e-12 46.6 0.3 3.2e-12 45.9 0.3 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RJW62332.1 - 1.5e-11 43.8 0.1 4e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF4209 PF13910.6 RJW62334.1 - 2e-16 60.0 0.7 1.4e-15 57.3 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4209) Forkhead PF00250.18 RJW62335.1 - 4.8e-11 42.7 0.0 1.2e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain HEAT PF02985.22 RJW62336.1 - 5.7e-21 72.8 12.8 0.00041 20.4 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat Arm PF00514.23 RJW62336.1 - 4e-17 61.6 6.8 0.0011 18.9 0.0 6.2 6 1 0 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RJW62336.1 - 2.4e-15 56.7 3.8 2.5e-12 47.0 0.4 3.9 2 2 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 RJW62336.1 - 2.1e-11 44.1 0.5 0.00028 21.3 0.0 5.0 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 RJW62336.1 - 2.1e-11 44.1 2.7 1.3e-06 28.6 0.0 3.4 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RJW62336.1 - 1.4e-08 33.8 1.0 2.3e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Proteasom_PSMB PF10508.9 RJW62336.1 - 2.4e-06 26.4 0.2 0.0096 14.5 0.0 3.6 1 1 3 4 4 4 1 Proteasome non-ATPase 26S subunit Arm_2 PF04826.13 RJW62336.1 - 4.9e-06 26.2 0.0 2.4e-05 23.9 0.0 1.9 1 1 1 2 2 2 1 Armadillo-like RICTOR_V PF14668.6 RJW62336.1 - 6.2e-05 23.2 0.1 0.019 15.2 0.0 3.3 2 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, domain 5 Vac14_Fab1_bd PF12755.7 RJW62336.1 - 0.00066 20.2 0.6 2.6 8.7 0.0 3.4 3 1 0 3 3 2 2 Vacuolar 14 Fab1-binding region IFRD PF05004.13 RJW62336.1 - 0.0013 17.9 3.3 1.5 7.8 0.0 3.9 1 1 2 4 4 4 1 Interferon-related developmental regulator (IFRD) RICTOR_N PF14664.6 RJW62336.1 - 0.0014 17.7 0.7 0.0054 15.8 0.4 1.9 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term DUF4042 PF13251.6 RJW62336.1 - 0.002 17.9 0.6 5.9 6.5 0.0 4.0 2 2 1 4 4 4 1 Domain of unknown function (DUF4042) RasGEF_N_2 PF14663.6 RJW62336.1 - 0.0024 18.3 0.4 3.1 8.2 0.0 3.9 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RTP1_C1 PF10363.9 RJW62336.1 - 0.0033 17.6 1.1 13 6.0 0.0 3.6 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 RJW62336.1 - 0.0065 15.8 0.1 2.6 7.2 0.0 2.1 1 1 1 2 2 2 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 RJW62336.1 - 0.0067 16.5 0.3 0.16 12.1 0.0 2.8 2 1 0 3 3 3 1 V-ATPase subunit H DUF3636 PF12331.8 RJW62336.1 - 0.007 16.2 0.1 1.8 8.4 0.1 3.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3636) TAF6_C PF07571.13 RJW62336.1 - 0.0078 16.5 0.4 0.33 11.3 0.1 2.7 2 1 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain HEAT_PBS PF03130.16 RJW62336.1 - 0.012 16.2 4.0 3.7 8.5 0.0 4.7 5 1 0 5 5 4 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 RJW62336.1 - 0.013 15.2 0.7 0.47 10.2 0.2 2.7 2 2 0 2 2 2 0 rRNA processing/ribosome biogenesis API5 PF05918.11 RJW62336.1 - 0.014 14.2 0.3 0.86 8.3 0.0 2.4 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) DUF2019 PF09450.10 RJW62336.1 - 0.022 14.7 0.6 4.9 7.2 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF2019) Tti2 PF10521.9 RJW62336.1 - 0.023 14.2 0.3 0.63 9.5 0.0 2.6 2 1 1 3 3 3 0 Tti2 family GP88 PF17338.2 RJW62336.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Gene product 88 Ipi1_N PF12333.8 RJW62336.1 - 0.15 12.7 0.1 1.1 9.9 0.0 2.3 3 0 0 3 3 2 0 Rix1 complex component involved in 60S ribosome maturation GYF PF02213.16 RJW62338.1 - 7.1e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 GYF domain Cadherin PF00028.17 RJW62339.1 - 1.9e-62 207.7 8.7 3.6e-17 62.6 0.5 8.3 7 1 1 8 8 8 8 Cadherin domain Cadherin_3 PF16184.5 RJW62339.1 - 0.0027 17.7 13.8 0.45 10.5 0.1 5.5 5 2 0 5 5 5 2 Cadherin-like Cadherin_4 PF17803.1 RJW62339.1 - 2.1 9.0 15.2 0.21 12.2 0.2 4.1 4 0 0 4 4 4 0 Bacterial cadherin-like domain CTP_transf_like PF01467.26 RJW62340.1 - 9.1e-13 48.6 0.0 3e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Cytidylyltransferase-like Pput2613-deam PF14427.6 RJW62340.1 - 0.0048 16.8 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 1 Pput_2613-like deaminase Cadherin PF00028.17 RJW62342.1 - 3.8e-51 171.5 1.7 1.1e-16 61.1 0.2 9.3 8 1 1 9 9 9 8 Cadherin domain Cadherin_2 PF08266.12 RJW62342.1 - 3.3e-09 36.5 0.0 0.00057 19.7 0.0 4.2 5 0 0 5 5 5 2 Cadherin-like Phage_sheath_1N PF17481.2 RJW62342.1 - 3.5e-05 24.2 0.1 0.0009 19.7 0.0 2.8 2 0 0 2 2 2 1 Phage tail sheath protein beta-sandwich domain PepSY PF03413.19 RJW62342.1 - 0.00064 20.2 1.0 0.0062 17.1 0.1 3.0 4 0 0 4 4 4 1 Peptidase propeptide and YPEB domain RET_CLD1 PF17756.1 RJW62342.1 - 0.1 12.9 0.0 16 5.8 0.0 3.8 4 1 1 5 5 5 0 RET Cadherin like domain 1 LapA_dom PF06305.11 RJW62342.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NOA36 PF06524.12 RJW62343.1 - 1.2e-75 254.7 31.2 1.5e-75 254.4 31.2 1.0 1 0 0 1 1 1 1 NOA36 protein Astro_capsid_p PF12226.8 RJW62343.1 - 0.34 10.0 6.4 0.45 9.6 6.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SWIRM-assoc_3 PF16498.5 RJW62344.1 - 0.12 12.6 0.1 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal Histone PF00125.24 RJW62345.1 - 5.4e-12 46.2 0.0 8.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 RJW62345.1 - 0.06 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 CENP-S protein LIM PF00412.22 RJW62346.1 - 1.2e-14 54.3 6.1 1.4e-14 54.1 6.1 1.1 1 0 0 1 1 1 1 LIM domain NinD PF17466.2 RJW62346.1 - 0.00078 19.5 1.1 0.0011 19.0 1.1 1.3 1 0 0 1 1 1 1 Family of unknown function zf-MYND PF01753.18 RJW62346.1 - 0.075 13.1 4.0 1.5 9.0 3.5 2.2 1 1 1 2 2 2 0 MYND finger TNFR_c6 PF00020.18 RJW62346.1 - 0.088 13.2 5.1 0.3 11.5 1.5 2.5 2 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region Fer4_2 PF12797.7 RJW62346.1 - 0.25 11.5 3.6 2.3 8.5 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain zf_UBZ PF18439.1 RJW62346.1 - 0.36 10.4 0.1 0.36 10.4 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger RT_RNaseH_2 PF17919.1 RJW62347.1 - 1.7e-38 130.7 0.0 3.4e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW62347.1 - 5.5e-35 119.8 0.0 1.2e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW62347.1 - 9e-24 84.2 0.0 1.4e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RJW62347.1 - 2.3e-22 79.4 0.0 5.3e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW62347.1 - 1.9e-12 47.1 0.1 1.9e-12 47.1 0.1 1.8 2 0 0 2 2 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RJW62347.1 - 3.5e-06 27.1 0.0 3.5e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 RJW62347.1 - 5.9e-05 22.8 0.0 0.0002 21.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 RJW62347.1 - 0.0032 18.0 0.0 0.0072 16.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 RJW62347.1 - 0.0057 16.9 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein RVP PF00077.20 RJW62347.1 - 0.026 14.8 0.0 0.069 13.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 RJW62347.1 - 0.053 14.2 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 RJW62347.1 - 0.59 10.3 9.3 0.63 10.2 0.8 3.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 RJW62347.1 - 8.6 6.3 8.5 0.2 11.5 1.3 2.1 2 0 0 2 2 1 0 Zinc knuckle zf-C2H2 PF00096.26 RJW62348.1 - 1.6e-23 81.8 43.6 4.5e-07 30.0 1.1 6.2 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW62348.1 - 8e-18 63.6 34.7 0.00012 22.6 0.8 6.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW62348.1 - 2.9e-15 55.9 44.9 1.3e-08 34.9 0.7 7.8 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW62348.1 - 1.4e-07 31.6 13.5 1.3 9.4 0.0 5.6 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RJW62348.1 - 1.1e-06 28.8 24.6 0.00097 19.4 3.1 4.5 2 2 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RJW62348.1 - 7.2e-06 25.9 27.3 0.0014 18.6 0.2 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW62348.1 - 0.045 13.5 0.4 0.045 13.5 0.4 5.9 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 RJW62348.1 - 0.2 11.6 15.4 2.2 8.3 0.2 5.7 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 RJW62348.1 - 0.29 10.8 10.5 7.7 6.2 0.2 4.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-WRNIP1_ubi PF18279.1 RJW62348.1 - 0.3 11.8 4.4 25 5.8 0.1 3.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-met PF12874.7 RJW62348.1 - 0.33 11.4 22.2 0.73 10.3 0.3 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-BED PF02892.15 RJW62348.1 - 0.43 10.6 30.9 0.75 9.9 0.9 5.1 3 2 2 5 5 5 0 BED zinc finger C1_4 PF07975.12 RJW62348.1 - 1.1 9.5 15.9 0.9 9.8 1.1 3.7 2 1 1 4 4 4 0 TFIIH C1-like domain PRP21_like_P PF12230.8 RJW62348.1 - 1.2 9.0 4.7 9.6 6.0 0.2 2.7 2 1 1 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_2 PF12756.7 RJW62348.1 - 3.1 8.2 32.4 1.5 9.2 1.5 5.5 3 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 RJW62348.1 - 3.7 8.4 18.5 5.8 7.7 5.9 3.2 2 1 1 3 3 3 0 zinc-ribbon family Zn-C2H2_12 PF18112.1 RJW62348.1 - 5.1 7.7 13.3 2 9.0 3.1 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain SAP18 PF06487.12 RJW62349.1 - 4.4e-36 124.1 0.0 7.5e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) ABC_tran PF00005.27 RJW62350.1 - 4.4e-38 130.9 0.1 1.3e-21 77.6 0.0 2.6 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 RJW62350.1 - 3.4e-13 50.1 1.0 0.0031 17.4 0.0 3.6 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RJW62350.1 - 6.2e-08 32.4 0.9 0.02 14.3 0.0 3.4 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 RJW62350.1 - 7.6e-07 29.1 9.3 7.6e-07 29.1 9.3 2.6 3 0 0 3 3 2 1 ABC transporter AAA_16 PF13191.6 RJW62350.1 - 0.0004 20.8 0.6 0.093 13.1 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 RJW62350.1 - 0.0014 18.6 0.4 0.0041 17.0 0.0 2.0 3 0 0 3 3 2 1 RsgA GTPase MMR_HSR1 PF01926.23 RJW62350.1 - 0.0019 18.2 0.3 0.016 15.3 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 RJW62350.1 - 0.0031 17.8 0.9 0.083 13.2 0.0 3.0 4 0 0 4 4 2 1 AAA domain AAA PF00004.29 RJW62350.1 - 0.005 17.3 0.3 0.81 10.1 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RJW62350.1 - 0.0075 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 RJW62350.1 - 0.012 16.2 2.5 2.2 8.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.6 RJW62350.1 - 0.013 15.5 0.0 6.8 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 RJW62350.1 - 0.04 13.6 1.1 0.078 12.7 0.0 2.0 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.12 RJW62350.1 - 0.049 13.6 0.1 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 RJW62350.1 - 0.051 14.1 10.6 0.15 12.5 0.0 3.1 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.23 RJW62350.1 - 0.061 13.4 0.3 8 6.5 0.0 3.0 3 0 0 3 3 3 0 Dynamin family RNA_helicase PF00910.22 RJW62350.1 - 0.062 13.7 0.0 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 RJW62350.1 - 0.064 13.0 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RJW62350.1 - 0.067 13.4 4.2 5.1 7.3 0.1 2.8 3 0 0 3 3 2 0 AAA domain DUF2408 PF10303.9 RJW62350.1 - 0.098 13.2 1.8 0.14 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) AAA_24 PF13479.6 RJW62350.1 - 0.11 12.2 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF1472 PF07339.12 RJW62350.1 - 0.16 12.5 0.1 0.5 10.9 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1472) Imm3 PF14425.6 RJW62350.1 - 0.27 11.3 2.8 0.86 9.7 0.2 2.5 2 0 0 2 2 2 0 Immunity protein Imm3 EF-hand_4 PF12763.7 RJW62351.1 - 3.8e-12 46.1 0.0 7.3e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 RJW62351.1 - 0.0017 17.8 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 RJW62351.1 - 0.0038 17.0 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 RJW62351.1 - 0.077 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair FOXP-CC PF16159.5 RJW62351.1 - 0.55 10.9 3.8 6.2 7.5 0.2 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain DLIC PF05783.11 RJW62352.1 - 5.8e-57 193.6 2.5 1.1e-43 149.8 1.0 2.8 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Dynein_light PF01221.18 RJW62354.1 - 1.4e-15 57.3 0.0 2.7e-15 56.5 0.0 1.5 2 0 0 2 2 2 1 Dynein light chain type 1 AAA_2 PF07724.14 RJW62354.1 - 0.1 12.7 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) COX6B PF02297.17 RJW62355.1 - 8.8e-12 45.1 4.3 1.4e-11 44.5 4.3 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb ADAM_CR_2 PF17771.1 RJW62355.1 - 0.075 13.6 0.2 0.13 12.8 0.1 1.5 1 1 0 1 1 1 0 ADAM cysteine-rich domain Patched PF02460.18 RJW62356.1 - 5.4e-64 216.6 14.5 1.3e-39 136.0 0.0 2.2 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 RJW62356.1 - 2.2e-47 161.7 1.4 3.3e-47 161.1 1.4 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 RJW62356.1 - 6.6e-43 146.2 30.6 1.1e-24 87.0 1.1 4.3 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 RJW62356.1 - 0.019 14.8 4.3 0.047 13.6 4.3 1.6 1 0 0 1 1 1 0 Folate receptor family DUF4337 PF14235.6 RJW62356.1 - 1.7 8.8 7.0 17 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) ArAE_2_N PF10337.9 RJW62356.1 - 5.6 5.9 8.1 11 5.0 8.1 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal RVT_1 PF00078.27 RJW62360.1 - 0.0093 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1676 PF07898.13 RJW62360.1 - 0.6 10.1 7.8 1.2 9.1 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) NCU-G1 PF15065.6 RJW62362.1 - 5.6e-18 65.1 1.2 6e-16 58.4 0.9 2.9 2 1 0 2 2 2 2 Lysosomal transcription factor, NCU-G1 RVT_1 PF00078.27 RJW62366.1 - 2.2e-07 30.6 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dynein_light PF01221.18 RJW62369.1 - 1.1e-27 96.2 1.9 1.2e-27 96.0 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Cep57_CLD_2 PF14197.6 RJW62369.1 - 0.18 11.9 0.2 0.23 11.6 0.2 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Dynein_light PF01221.18 RJW62370.1 - 2e-23 82.5 0.1 2.7e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4495 PF14906.6 RJW62370.1 - 0.026 13.6 0.1 0.036 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) HutP PF09021.11 RJW62370.1 - 0.042 14.2 0.2 0.068 13.5 0.2 1.5 1 1 0 1 1 1 0 HutP RRM_1 PF00076.22 RJW62371.1 - 8.7e-14 51.1 0.1 1.6e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 RJW62371.1 - 0.026 14.6 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain Guanylate_cyc PF00211.20 RJW62372.1 - 9.6e-84 279.6 1.9 3e-46 157.3 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain CAP_GLY PF01302.25 RJW62373.1 - 5.6e-71 234.5 6.5 2.7e-24 85.0 0.2 3.6 3 0 0 3 3 3 3 CAP-Gly domain PIG-U PF06728.13 RJW62373.1 - 6.8e-71 239.3 28.7 8.9e-71 239.0 28.7 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Ank PF00023.30 RJW62373.1 - 1.2e-08 35.0 0.2 0.02 15.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RJW62373.1 - 3.4e-08 34.0 0.0 3.4e-06 27.6 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW62373.1 - 2.3e-06 28.0 0.1 0.00081 19.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW62373.1 - 1.6e-05 24.9 0.5 0.37 11.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RJW62373.1 - 0.00061 20.0 1.5 0.071 13.5 0.1 3.7 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Spo0M PF07070.11 RJW62373.1 - 0.25 10.9 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 SpoOM protein DUF4200 PF13863.6 RJW62374.1 - 0.016 15.6 15.1 0.016 15.6 15.1 6.4 2 2 3 6 6 6 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 RJW62374.1 - 0.016 15.7 12.7 0.016 15.7 12.7 5.6 2 2 3 5 5 5 0 Apg6 coiled-coil region LRR_4 PF12799.7 RJW62376.1 - 2.7e-07 30.8 10.9 0.00015 22.1 2.4 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW62376.1 - 6e-05 22.6 4.6 0.00095 18.7 0.2 2.5 3 0 0 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 RJW62376.1 - 7.8e-05 22.4 5.0 0.00026 20.7 5.0 2.0 1 1 0 1 1 1 1 Leucine rich repeat DUF724 PF05266.14 RJW62376.1 - 0.051 13.4 4.5 0.078 12.8 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LRR_6 PF13516.6 RJW62376.1 - 0.076 13.1 5.7 2.1 8.6 0.4 3.6 4 0 0 4 4 3 0 Leucine Rich repeat DUF5076 PF16826.5 RJW62376.1 - 0.084 12.8 0.3 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5076) Creatinase_N_2 PF16189.5 RJW62376.1 - 0.14 12.2 0.5 16 5.6 0.0 2.5 1 1 0 2 2 2 0 Creatinase/Prolidase N-terminal domain GPHR_N PF12537.8 RJW62376.1 - 0.16 12.0 1.1 7.5 6.7 0.3 2.8 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Tropomyosin_1 PF12718.7 RJW62376.1 - 0.21 11.7 8.8 0.43 10.7 8.8 1.5 1 0 0 1 1 1 0 Tropomyosin like DUF3552 PF12072.8 RJW62376.1 - 0.24 10.8 8.0 0.34 10.3 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) LRR_1 PF00560.33 RJW62376.1 - 0.33 11.7 5.3 30 5.7 2.4 3.5 2 1 0 2 2 2 0 Leucine Rich Repeat ATG16 PF08614.11 RJW62376.1 - 0.49 10.6 15.3 0.76 10.0 15.3 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Sec2p PF06428.11 RJW62376.1 - 0.95 9.5 10.5 1.7 8.7 8.5 2.3 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p FUSC PF04632.12 RJW62376.1 - 5.9 5.3 7.0 7.4 5.0 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family NCU-G1 PF15065.6 RJW62377.1 - 1.1e-62 212.1 0.0 1.6e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 DUF2275 PF10039.9 RJW62378.1 - 3.4 7.7 6.7 0.61 10.1 2.6 1.7 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) LIM PF00412.22 RJW62380.1 - 1.3e-24 86.2 19.0 4.7e-12 45.9 11.9 2.5 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 RJW62380.1 - 1e-17 63.7 2.2 2.1e-17 62.7 2.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW62380.1 - 0.0058 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 RJW62380.1 - 0.12 11.8 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Vps39_2 PF10367.9 RJW62380.1 - 5.4 7.5 7.4 27 5.2 1.7 3.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF3446 PF11928.8 RJW62381.1 - 0.048 14.0 14.3 0.054 13.8 14.3 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain SR-25 PF10500.9 RJW62381.1 - 0.075 12.6 19.3 0.075 12.6 19.3 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 RJW62381.1 - 0.66 9.6 4.7 0.69 9.6 4.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Chorion_2 PF03964.15 RJW62381.1 - 0.96 10.3 9.1 1 10.2 9.1 1.1 1 0 0 1 1 1 0 Chorion family 2 DUF1635 PF07795.11 RJW62381.1 - 0.99 9.2 4.7 0.92 9.3 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF508 PF04370.12 RJW62381.1 - 1.5 8.6 10.1 1.6 8.4 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF508) IMUP PF15761.5 RJW62381.1 - 4 8.2 16.3 5.3 7.8 16.3 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein Herpes_pp85 PF04637.12 RJW62381.1 - 7 4.9 13.5 7.6 4.8 13.5 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) LRR_4 PF12799.7 RJW62382.1 - 0.0068 16.8 0.3 1.6 9.3 0.0 2.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RJW62382.1 - 0.0097 15.9 0.2 3.4 7.9 0.0 3.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 RJW62382.1 - 0.045 14.3 0.9 14 6.7 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat PAN_1 PF00024.26 RJW62383.1 - 0.0036 17.2 4.2 0.0091 15.9 4.2 1.8 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RJW62383.1 - 0.011 15.7 0.2 0.022 14.7 0.2 1.5 1 0 0 1 1 1 0 PAN domain MANEC PF07502.14 RJW62383.1 - 0.093 13.0 2.9 0.11 12.8 0.5 2.3 2 0 0 2 2 2 0 MANEC domain DUF5641 PF18701.1 RJW62384.1 - 9.8e-05 22.4 3.6 0.00036 20.6 0.4 2.8 3 1 0 3 3 3 1 Family of unknown function (DUF5641) Lig_chan PF00060.26 RJW62385.1 - 5.4e-46 156.1 0.0 8.5e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RJW62385.1 - 1.4e-28 99.4 0.0 2.8e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 RJW62385.1 - 1e-18 67.6 0.0 1.6e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 RJW62385.1 - 1.6e-18 67.0 0.0 5e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 RJW62385.1 - 0.27 11.2 2.9 0.98 9.4 2.9 2.0 1 1 0 1 1 1 0 Ion channel Sel1 PF08238.12 RJW62387.1 - 0.00011 22.7 0.1 0.00025 21.6 0.1 1.7 1 0 0 1 1 1 1 Sel1 repeat DUF1707 PF08044.11 RJW62387.1 - 0.13 12.3 1.0 6.5 6.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Kelch_1 PF01344.25 RJW62388.1 - 4e-78 256.8 18.3 2.6e-17 62.1 0.3 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 RJW62388.1 - 4.3e-38 128.4 7.6 1.1e-07 31.8 0.1 6.7 4 2 3 7 7 7 5 Kelch motif Kelch_3 PF13415.6 RJW62388.1 - 4.1e-30 103.5 12.7 1e-06 28.9 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 RJW62388.1 - 8.3e-30 103.3 0.1 1.4e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 RJW62388.1 - 4.7e-29 99.2 3.8 2.8e-07 30.2 0.3 5.9 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 RJW62388.1 - 2.2e-28 98.0 1.0 1e-05 25.4 0.0 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain BACK PF07707.15 RJW62388.1 - 2.2e-28 98.3 0.4 4.2e-28 97.5 0.4 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 RJW62388.1 - 3.5e-08 33.3 8.0 0.55 10.3 0.0 5.4 5 0 0 5 5 5 3 Kelch motif SPRY PF00622.28 RJW62388.1 - 6.7e-07 29.4 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 SPRY domain PQQ_3 PF13570.6 RJW62388.1 - 0.0012 19.2 10.6 0.12 12.9 0.3 5.4 5 0 0 5 5 5 1 PQQ-like domain Ank_4 PF13637.6 RJW62389.1 - 8.2e-22 77.3 0.4 3e-10 40.4 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW62389.1 - 8e-21 74.4 2.7 6.9e-08 33.0 0.3 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW62389.1 - 5.8e-15 53.9 2.0 0.0028 18.0 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 RJW62389.1 - 7.8e-15 54.6 4.3 0.0003 21.1 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat PDZ_6 PF17820.1 RJW62389.1 - 2.3e-14 53.0 0.2 6.2e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 RJW62389.1 - 4.8e-14 52.5 0.0 9.8e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Ank_5 PF13857.6 RJW62389.1 - 1.2e-13 51.0 2.6 6.6e-07 29.5 0.1 4.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) PDZ_2 PF13180.6 RJW62389.1 - 0.00031 21.0 0.0 0.00071 19.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Utp14 PF04615.13 RJW62389.1 - 0.39 9.2 4.8 0.075 11.6 0.7 1.7 2 0 0 2 2 2 0 Utp14 protein Lig_chan PF00060.26 RJW62390.1 - 4.9e-33 114.1 0.0 9.1e-33 113.2 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 RJW62390.1 - 2.2e-29 102.7 0.1 2.1e-28 99.5 0.1 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 RJW62390.1 - 4.3e-26 91.4 0.0 6.3e-25 87.6 0.0 2.4 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RJW62390.1 - 4.4e-21 75.4 0.0 9e-20 71.1 0.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 RJW62390.1 - 0.014 15.3 0.2 0.014 15.3 0.2 1.9 2 0 0 2 2 2 0 Ion channel Antifungal_pept PF11410.8 RJW62390.1 - 1.4 8.9 4.6 0.88 9.5 0.6 2.4 2 0 0 2 2 2 0 Antifungal peptide PBP1_TM PF14812.6 RJW62391.1 - 0.0034 17.7 4.5 0.0055 17.1 4.5 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 RJW62391.1 - 0.23 11.1 1.5 0.4 10.3 1.5 1.4 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 RJW62391.1 - 0.32 9.0 3.9 0.4 8.7 3.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YL1 PF05764.13 RJW62391.1 - 2.8 8.0 5.4 3.6 7.6 5.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CENP-B_dimeris PF09026.10 RJW62391.1 - 3.7 8.0 17.3 5.8 7.4 17.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SNF2_N PF00176.23 RJW62392.1 - 3.1e-55 187.3 0.7 5.1e-55 186.6 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW62392.1 - 1.1e-16 61.1 0.0 3e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 RJW62392.1 - 1.1e-11 44.4 0.9 0.00027 20.8 0.0 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 RJW62392.1 - 2.1e-07 31.1 0.0 7.5e-07 29.3 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RJW62392.1 - 0.00091 19.0 0.0 0.0042 16.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RJW62392.1 - 0.02 15.2 0.0 0.13 12.6 0.0 2.5 1 1 0 1 1 1 0 AAA domain Creatininase PF02633.14 RJW62392.1 - 0.092 12.2 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Creatinine amidohydrolase DUF4201 PF13870.6 RJW62394.1 - 1.1e-25 90.4 27.3 1.1e-25 90.3 26.5 1.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Prominin PF05478.11 RJW62394.1 - 0.3 9.0 10.3 0.38 8.7 10.3 1.2 1 0 0 1 1 1 0 Prominin DUF743 PF05332.11 RJW62394.1 - 3.8 7.6 9.1 6.1 6.9 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF743) CAP PF00188.26 RJW62395.1 - 3.3e-08 34.4 4.1 4.8e-08 33.9 3.3 1.7 1 1 1 2 2 2 1 Cysteine-rich secretory protein family bZIP_Maf PF03131.17 RJW62396.1 - 4.2e-17 62.4 16.5 5.2e-17 62.2 16.0 1.4 1 1 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 RJW62396.1 - 1.5e-05 25.0 12.8 2.5e-05 24.3 12.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor Bap31_Bap29_C PF18035.1 RJW62396.1 - 0.043 13.8 0.7 0.043 13.8 0.7 1.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Cut12 PF11500.8 RJW62396.1 - 0.14 12.1 4.3 0.21 11.5 4.3 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein bZIP_2 PF07716.15 RJW62396.1 - 0.45 10.6 12.9 0.91 9.6 12.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Exonuc_VII_L PF02601.15 RJW62396.1 - 0.59 9.7 4.3 0.71 9.4 4.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAGH_C PF16123.5 RJW62397.1 - 9.5e-26 90.1 0.1 1.4e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 RJW62397.1 - 1.9e-10 41.1 5.3 1.1e-09 38.6 4.4 2.3 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RJW62397.1 - 0.031 13.8 0.3 0.074 12.6 0.3 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Peptidase_C14 PF00656.22 RJW62398.1 - 2.3e-39 135.8 0.0 2.9e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CDP-OH_P_transf PF01066.21 RJW62401.1 - 2.9e-14 53.6 0.2 2.9e-14 53.6 0.2 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Neur_chan_LBD PF02931.23 RJW62402.1 - 2.4e-40 138.3 1.0 3.3e-40 137.8 1.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW62402.1 - 0.0058 16.7 2.7 0.0058 16.7 2.7 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region BRI3BP PF14965.6 RJW62402.1 - 0.55 9.7 4.6 0.2 11.1 1.9 1.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF2070 PF09843.9 RJW62402.1 - 0.57 8.4 2.9 0.83 7.9 2.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Sybindin PF04099.12 RJW62403.1 - 2.2e-32 112.0 0.0 2.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 RJW62403.1 - 1.9e-07 31.2 0.0 2.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Tmemb_185A PF10269.9 RJW62406.1 - 0.00086 19.1 9.6 0.0023 17.6 9.6 1.7 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein Spore_YabQ PF09578.10 RJW62406.1 - 0.048 13.9 0.1 0.048 13.9 0.1 2.3 3 0 0 3 3 3 0 Spore cortex protein YabQ (Spore_YabQ) AdoHcyase PF05221.17 RJW62409.1 - 6.6e-133 442.4 0.0 1.1e-70 238.1 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 RJW62409.1 - 1.9e-81 271.8 0.8 3.1e-81 271.2 0.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 RJW62409.1 - 7.6e-05 22.3 0.1 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 RJW62409.1 - 0.00017 21.0 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 RJW62409.1 - 0.0022 18.2 0.0 0.0049 17.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 RJW62409.1 - 0.062 12.0 0.0 0.4 9.4 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_7 PF13241.6 RJW62409.1 - 0.071 13.6 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding MoeA_N PF03453.17 RJW62409.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 MoeA N-terminal region (domain I and II) SBP_bac_6 PF13343.6 RJW62412.1 - 0.093 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DUF4131 PF13567.6 RJW62412.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) rRNA_proc-arch PF13234.6 RJW62413.1 - 2.5e-64 217.8 0.0 3.6e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 RJW62413.1 - 9.8e-53 178.2 0.1 1.8e-52 177.3 0.1 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 RJW62413.1 - 8.9e-18 64.7 0.0 2.4e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW62413.1 - 1.9e-06 28.2 0.0 6.4e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW62413.1 - 2.2e-05 24.5 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RJW62413.1 - 0.0012 19.2 0.0 0.0048 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 RJW62413.1 - 0.2 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea tRNA-synt_2b PF00587.25 RJW62414.1 - 5.3e-10 39.5 0.0 1.5e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) RA PF00788.23 RJW62415.1 - 3.1e-24 85.4 0.0 3.7e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 RJW62415.1 - 6.2e-15 55.3 0.1 2.8e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 DIL domain zf-C2H2_4 PF13894.6 RJW62417.1 - 9.2e-06 26.1 8.8 0.015 16.1 0.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW62417.1 - 0.00034 20.9 6.8 0.0081 16.6 0.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 RJW62417.1 - 0.0041 17.0 1.7 0.0041 17.0 1.7 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 RJW62417.1 - 0.0088 15.8 7.1 0.43 10.4 0.6 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-BED PF02892.15 RJW62417.1 - 0.0098 15.9 7.7 0.16 12.0 1.2 2.6 1 1 1 2 2 2 2 BED zinc finger zf-H2C2_2 PF13465.6 RJW62417.1 - 0.017 15.5 5.7 2.5 8.7 1.4 2.8 2 0 0 2 2 2 0 Zinc-finger double domain RAG1_imp_bd PF12560.8 RJW62417.1 - 0.021 14.4 0.7 0.038 13.5 0.7 1.3 1 0 0 1 1 1 0 RAG1 importin binding zf-C2H2_3rep PF18868.1 RJW62417.1 - 0.028 15.1 2.2 1.8 9.3 0.2 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats ADK_lid PF05191.14 RJW62417.1 - 0.09 12.8 0.3 0.19 11.7 0.3 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid Lar_restr_allev PF14354.6 RJW62417.1 - 0.16 12.3 1.5 0.35 11.3 1.5 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 RJW62417.1 - 0.43 10.7 5.1 2.8 8.1 3.9 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 RJW62417.1 - 3.9 7.9 8.9 7.7 6.9 1.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 RJW62417.1 - 7.1 6.3 9.0 0.34 10.5 0.8 2.4 2 0 0 2 2 2 0 MYST family zinc finger domain Zf_RING PF16744.5 RJW62417.1 - 8.5 6.6 8.0 26 5.0 1.4 2.5 1 1 1 2 2 2 0 KIAA1045 RING finger zf-AN1 PF01428.16 RJW62417.1 - 9 6.6 6.7 23 5.3 0.8 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger Myotub-related PF06602.14 RJW62418.1 - 1.7e-05 24.0 1.1 0.0006 18.8 1.1 2.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 RJW62418.1 - 0.0013 18.8 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Acyltransferase PF01553.21 RJW62419.1 - 8.7e-13 48.1 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 RJW62419.1 - 4e-08 33.2 0.0 8.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus RVT_1 PF00078.27 RJW62421.1 - 9.3e-45 152.8 0.0 1.4e-44 152.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_PH PF01138.21 RJW62421.1 - 1.1e-10 42.1 0.2 1.3e-09 38.6 0.0 2.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Exo_endo_phos_2 PF14529.6 RJW62421.1 - 5.7e-07 29.4 0.0 1.6e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW62421.1 - 7.1e-07 29.0 1.1 1.8e-06 27.7 0.4 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Yippee-Mis18 PF03226.14 RJW62422.1 - 9.8e-10 38.6 0.0 1.6e-09 37.9 0.0 1.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 RJW62422.1 - 0.013 15.3 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease Endonuclease_7 PF02945.15 RJW62422.1 - 0.015 15.2 0.2 0.03 14.2 0.0 1.5 2 0 0 2 2 2 0 Recombination endonuclease VII AFG1_ATPase PF03969.16 RJW62423.1 - 4.4e-37 127.8 0.0 5.1e-35 121.0 0.0 2.0 1 1 1 2 2 2 2 AFG1-like ATPase DC_STAMP PF07782.13 RJW62424.1 - 1.5e-36 126.1 0.4 8.8e-36 123.5 0.1 2.3 2 0 0 2 2 2 1 DC-STAMP-like protein zf-C3HC4_3 PF13920.6 RJW62424.1 - 0.016 15.0 4.9 0.055 13.3 4.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW62424.1 - 0.94 9.9 5.2 3.6 8.0 5.2 2.1 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 RJW62424.1 - 1.3 9.1 4.0 3.6 7.7 4.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon Kelch_1 PF01344.25 RJW62425.1 - 2.6e-79 260.6 18.9 3.3e-16 58.6 0.0 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RJW62425.1 - 4e-49 163.4 11.2 3.2e-08 33.6 0.0 6.4 2 2 4 6 6 6 6 Kelch motif Kelch_3 PF13415.6 RJW62425.1 - 2.1e-35 120.3 7.4 7.2e-08 32.5 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 RJW62425.1 - 1.8e-33 113.3 7.0 5.7e-07 29.3 0.0 6.9 6 1 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RJW62425.1 - 2e-28 98.2 5.4 4.4e-06 26.6 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 RJW62425.1 - 2.6e-27 95.2 0.4 4.1e-27 94.6 0.4 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RJW62425.1 - 4.1e-26 91.1 1.3 1.4e-25 89.4 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 RJW62425.1 - 1.6e-14 53.5 5.0 0.0013 18.7 0.0 5.5 5 0 0 5 5 5 3 Kelch motif DUF3342 PF11822.8 RJW62425.1 - 0.009 16.2 0.7 0.23 11.7 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) DUF2798 PF11391.8 RJW62426.1 - 0.0058 16.6 13.1 0.013 15.5 13.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2798) Romo1 PF10247.9 RJW62426.1 - 0.0077 16.6 3.5 0.39 11.1 0.3 2.1 1 1 1 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.6 RJW62426.1 - 0.02 14.9 4.4 0.034 14.1 4.4 1.5 1 1 0 1 1 1 0 Glycine zipper DUF5455 PF17537.2 RJW62426.1 - 0.41 11.1 5.9 29 5.1 5.9 2.2 1 1 0 1 1 1 0 Family of unknown function (DUF5455) FeoB_C PF07664.12 RJW62426.1 - 0.87 9.3 7.5 94 2.8 7.5 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B C terminus FtsX PF02687.21 RJW62426.1 - 6.6 7.3 10.0 2e+02 2.5 10.0 2.0 1 1 0 1 1 1 0 FtsX-like permease family PPTA PF01239.22 RJW62427.1 - 1e-05 25.1 11.8 5e-05 22.9 0.1 4.4 4 1 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 RJW62427.1 - 0.068 14.0 0.1 3.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat C2 PF00168.30 RJW62428.1 - 6.5e-05 23.2 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain Kunitz_BPTI PF00014.23 RJW62429.1 - 7.3e-14 51.7 9.9 7.3e-14 51.7 9.9 1.7 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain LRR_4 PF12799.7 RJW62430.1 - 4.3e-16 58.8 11.9 5.4e-09 36.2 2.3 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW62430.1 - 1.1e-14 54.3 0.3 1.6e-14 53.8 0.3 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RJW62430.1 - 4.6e-09 35.9 11.8 6.9e-06 25.7 6.4 3.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_2 PF07723.13 RJW62430.1 - 0.18 12.5 2.2 4.1 8.2 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat BUD22 PF09073.10 RJW62430.1 - 0.38 10.1 25.3 0.48 9.7 25.3 1.2 1 0 0 1 1 1 0 BUD22 LRR_6 PF13516.6 RJW62430.1 - 0.44 10.7 0.1 0.44 10.7 0.1 4.8 6 0 0 6 6 6 0 Leucine Rich repeat SDA1 PF05285.12 RJW62430.1 - 1.5 8.2 28.4 1.9 7.8 28.4 1.1 1 0 0 1 1 1 0 SDA1 LRR_1 PF00560.33 RJW62430.1 - 1.8 9.4 11.6 8.8 7.3 0.4 5.0 5 1 0 5 5 5 0 Leucine Rich Repeat EGF_2 PF07974.13 RJW62432.1 - 0.0017 18.7 19.4 0.0036 17.6 0.3 5.5 4 1 0 4 4 4 2 EGF-like domain EGF PF00008.27 RJW62432.1 - 0.0022 18.3 6.6 0.0022 18.3 6.6 5.3 4 2 0 4 4 4 2 EGF-like domain hEGF PF12661.7 RJW62432.1 - 0.075 13.7 18.9 3.1 8.6 0.7 5.3 4 0 0 4 4 4 0 Human growth factor-like EGF TSP_1 PF00090.19 RJW62432.1 - 0.15 12.3 7.2 0.48 10.7 7.2 2.0 1 0 0 1 1 1 0 Thrombospondin type 1 domain ig PF00047.25 RJW62434.1 - 2e-12 47.1 0.1 7.5e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 RJW62434.1 - 1.3e-10 41.8 0.2 3.3e-07 30.8 0.1 3.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RJW62434.1 - 4.2e-10 39.6 0.0 4.6e-06 26.6 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW62434.1 - 1.2e-05 25.6 0.1 0.00065 20.0 0.1 2.7 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 RJW62434.1 - 0.021 14.8 0.1 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Lung_7-TM_R PF06814.13 RJW62435.1 - 1.2e-63 215.2 19.1 1.2e-63 215.2 19.1 1.4 2 0 0 2 2 2 1 Lung seven transmembrane receptor RVT_1 PF00078.27 RJW62435.1 - 8.1e-43 146.5 0.0 1.3e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GpcrRhopsn4 PF10192.9 RJW62435.1 - 6.7e-05 22.4 8.1 0.00014 21.4 7.9 1.7 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain TPR_1 PF00515.28 RJW62436.1 - 1.3e-23 81.7 19.9 2.3e-07 30.3 0.3 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 RJW62436.1 - 5.4e-17 60.5 24.9 4.5e-05 23.2 0.2 9.5 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 RJW62436.1 - 7e-15 54.4 5.2 0.00037 20.1 0.2 7.2 6 1 1 7 7 7 4 TPR repeat TPR_14 PF13428.6 RJW62436.1 - 1.7e-09 37.7 22.3 0.097 13.5 0.0 9.4 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 RJW62436.1 - 2.4e-07 30.4 14.1 1.7 9.0 0.0 8.6 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW62436.1 - 6e-07 29.9 26.9 0.39 11.2 0.1 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 RJW62436.1 - 3.7e-06 27.1 22.1 0.056 13.7 0.0 7.8 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 RJW62436.1 - 1.3e-05 25.2 16.0 0.33 11.1 0.4 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW62436.1 - 1.8e-05 24.8 17.3 1.9 9.0 0.1 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat MIT PF04212.18 RJW62436.1 - 0.00012 22.1 11.9 0.18 11.9 0.1 4.9 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 RJW62436.1 - 0.00062 20.4 22.1 0.26 12.0 0.6 6.1 5 2 2 7 7 7 4 Tetratricopeptide repeat SHNi-TPR PF10516.9 RJW62436.1 - 0.00083 18.8 0.8 0.19 11.2 0.0 3.7 3 0 0 3 3 3 1 SHNi-TPR TPR_21 PF09976.9 RJW62436.1 - 0.012 15.3 0.7 0.012 15.3 0.7 4.2 3 2 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 RJW62436.1 - 0.038 14.6 0.5 30 5.6 0.0 3.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW62436.1 - 0.045 13.8 12.0 3.7 7.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 RJW62436.1 - 0.33 10.1 8.3 0.84 8.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA_int_endo PF01974.17 RJW62437.1 - 2.7e-14 53.0 0.1 4.5e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 RJW62437.1 - 0.011 15.4 0.2 0.053 13.2 0.0 2.2 2 1 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain Homeodomain PF00046.29 RJW62441.1 - 4.2e-22 77.7 2.0 8.8e-22 76.7 2.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW62441.1 - 0.0077 16.1 0.2 0.028 14.3 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain Glu_cys_ligase PF04262.14 RJW62441.1 - 0.051 12.2 0.1 0.076 11.6 0.1 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase Glyphos_transf PF04464.14 RJW62441.1 - 0.16 10.9 0.9 7.5 5.4 0.1 2.1 2 0 0 2 2 2 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Ion_trans PF00520.31 RJW62442.1 - 1.4e-34 119.5 17.0 2.3e-34 118.7 17.0 1.3 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW62442.1 - 3.3e-10 39.8 5.6 3.3e-10 39.8 5.6 2.0 2 0 0 2 2 2 1 Ion channel DUF1759 PF03564.15 RJW62443.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) KCNQ_channel PF03520.14 RJW62444.1 - 6.3e-33 114.2 0.4 1.2e-32 113.3 0.1 1.6 2 0 0 2 2 2 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 RJW62444.1 - 1.3e-25 90.0 8.0 2.1e-25 89.4 8.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW62444.1 - 1.4e-13 50.6 2.9 5.1e-13 48.8 2.9 2.0 1 0 0 1 1 1 1 Ion channel IQ PF00612.27 RJW62444.1 - 0.053 13.3 2.1 0.19 11.6 0.1 3.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Calponin PF00402.18 RJW62445.1 - 5.8e-61 201.7 48.0 1.2e-13 50.4 2.0 5.7 5 0 0 5 5 5 5 Calponin family repeat CH PF00307.31 RJW62445.1 - 2e-19 69.7 0.0 3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain PhoLip_ATPase_C PF16212.5 RJW62446.1 - 7.6e-50 170.0 25.7 1e-49 169.6 25.7 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 RJW62446.1 - 1.9e-11 44.7 0.1 3.7e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RJW62446.1 - 1e-07 31.9 0.3 4.7e-06 26.6 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RJW62446.1 - 0.0058 16.4 0.1 0.95 9.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 RJW62446.1 - 0.012 16.1 0.1 0.12 12.7 0.0 2.5 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 RJW62446.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Kunitz_BPTI PF00014.23 RJW62447.1 - 1.7e-15 57.0 2.0 2.1e-15 56.7 2.0 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Tetraspanin PF00335.20 RJW62448.1 - 7.3e-17 61.8 4.0 1.1e-16 61.3 4.0 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 RJW62448.1 - 0.00099 19.4 0.9 0.00099 19.4 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) Zn_peptidase_2 PF04298.12 RJW62448.1 - 0.64 9.4 3.1 1.8 7.9 1.9 2.0 1 1 0 2 2 2 0 Putative neutral zinc metallopeptidase Annexin PF00191.20 RJW62449.1 - 1.4e-60 201.3 1.7 1.4e-18 66.7 0.0 4.9 4 1 0 4 4 4 4 Annexin Fe_hyd_SSU PF02256.17 RJW62449.1 - 0.056 13.5 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 Iron hydrogenase small subunit Toxin_2 PF00451.19 RJW62450.1 - 0.93 9.9 6.7 0.38 11.1 0.9 2.6 2 1 1 3 3 3 0 Scorpion short toxin, BmKK2 DUF5038 PF16441.5 RJW62451.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5038) RRM_1 PF00076.22 RJW62453.1 - 2.3e-09 37.0 0.0 6.5e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC106 PF15794.5 RJW62454.1 - 0.0016 18.2 9.5 0.0083 15.9 0.7 2.7 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 106 DUF1635 PF07795.11 RJW62454.1 - 0.0043 16.9 0.4 0.0043 16.9 0.4 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1635) YabA PF06156.13 RJW62454.1 - 0.094 13.4 6.9 1.2 9.8 0.1 3.2 3 0 0 3 3 3 0 Initiation control protein YabA PI3K_P85_iSH2 PF16454.5 RJW62454.1 - 0.18 11.4 0.1 0.18 11.4 0.1 2.3 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 RJW62454.1 - 0.23 12.0 0.1 0.23 12.0 0.1 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF3450 PF11932.8 RJW62454.1 - 0.54 9.5 9.5 0.83 8.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Prefoldin PF02996.17 RJW62454.1 - 2.7 7.9 4.9 4.7 7.1 0.9 2.6 2 0 0 2 2 2 0 Prefoldin subunit Noelin-1 PF12308.8 RJW62454.1 - 3.8 7.6 6.2 0.69 9.9 0.1 2.5 3 0 0 3 3 3 0 Neurogenesis glycoprotein DUF4164 PF13747.6 RJW62454.1 - 4.7 7.6 10.5 0.093 13.0 1.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) GOLGA2L5 PF15070.6 RJW62454.1 - 7 5.2 12.5 0.63 8.6 0.8 2.7 2 1 1 3 3 3 0 Putative golgin subfamily A member 2-like protein 5 GAS PF13851.6 RJW62454.1 - 7.8 5.8 14.5 0.44 9.9 1.1 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Dynactin_p62 PF05502.13 RJW62455.1 - 1.2e-33 116.7 20.8 3.3e-20 72.3 10.6 2.1 2 0 0 2 2 2 2 Dynactin p62 family Choline_sulf_C PF12411.8 RJW62455.1 - 0.15 11.9 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal I-set PF07679.16 RJW62456.1 - 7.4e-15 54.8 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW62456.1 - 2.9e-14 53.4 0.0 6.7e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RJW62456.1 - 3.9e-11 43.1 0.0 2.3e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RJW62456.1 - 5.1e-09 36.2 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RJW62456.1 - 0.00022 21.3 0.0 0.0026 17.9 0.0 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 RJW62456.1 - 0.015 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain C1_2 PF03107.16 RJW62457.1 - 3 8.2 11.6 0.3 11.4 6.2 2.1 2 0 0 2 2 2 0 C1 domain Ras PF00071.22 RJW62458.1 - 2e-45 154.3 0.0 3.1e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW62458.1 - 4.1e-16 59.3 0.0 6.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW62458.1 - 1.6e-06 27.7 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW62458.1 - 9.2e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 RJW62458.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 RJW62458.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 1 0 1 1 1 0 RsgA GTPase Band_7 PF01145.25 RJW62459.1 - 9.3e-08 32.3 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family SCP2 PF02036.17 RJW62459.1 - 0.00021 21.7 0.6 0.00076 19.9 0.0 2.2 4 0 0 4 4 4 1 SCP-2 sterol transfer family ARF7EP_C PF14949.6 RJW62460.1 - 1.1e-29 103.1 3.7 1.9e-29 102.3 3.7 1.4 1 0 0 1 1 1 1 ARF7 effector protein C-terminus SPRY PF00622.28 RJW62461.1 - 8.6e-21 74.3 0.8 2.3e-19 69.7 0.1 2.3 2 0 0 2 2 2 1 SPRY domain CLTH PF10607.9 RJW62461.1 - 2.9e-17 62.9 0.0 5.3e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 RJW62461.1 - 0.0002 21.2 0.0 0.00054 19.8 0.0 1.8 2 0 0 2 2 2 1 LisH NOA36 PF06524.12 RJW62461.1 - 2.4 7.4 28.9 0.26 10.6 17.3 2.2 2 0 0 2 2 2 0 NOA36 protein Cwf_Cwc_15 PF04889.12 RJW62461.1 - 9.9 5.8 25.8 12 5.5 1.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Autophagy_N PF03986.13 RJW62462.1 - 3.8e-44 150.0 0.2 6.1e-44 149.3 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 RJW62462.1 - 7.7e-20 71.2 1.7 1.3e-19 70.5 0.8 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 RJW62462.1 - 5.8e-15 54.5 1.9 1.3e-14 53.4 1.9 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Importin_rep_6 PF18829.1 RJW62462.1 - 0.39 10.9 2.6 2.8 8.1 0.3 2.6 2 0 0 2 2 2 0 Importin repeat 6 MTA_R1 PF17226.2 RJW62463.1 - 0.0019 18.3 0.7 0.0044 17.1 0.7 1.7 1 0 0 1 1 1 1 MTA R1 domain GATA PF00320.27 RJW62463.1 - 0.003 17.1 1.5 0.003 17.1 1.5 1.8 2 0 0 2 2 2 1 GATA zinc finger DUF5578 PF17741.1 RJW62463.1 - 0.038 13.4 0.3 0.054 12.9 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5578) DUF4147 PF13660.6 RJW62465.1 - 8.3e-48 162.9 0.0 1.9e-47 161.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 RJW62465.1 - 3.1e-19 69.2 0.0 6.9e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 MOFRL family DUF1992 PF09350.10 RJW62467.1 - 1.9e-20 72.8 0.0 7.1e-20 70.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) RNase_P_p30 PF01876.16 RJW62468.1 - 2.6e-26 92.4 0.0 1.1e-25 90.4 0.0 1.9 1 1 0 1 1 1 1 RNase P subunit p30 Annexin PF00191.20 RJW62469.1 - 2.8e-23 81.7 0.1 5.9e-09 35.9 0.0 4.8 4 1 0 4 4 4 3 Annexin Collagen PF01391.18 RJW62470.1 - 4e-161 522.9 636.8 1.3e-08 34.5 26.2 21.3 2 1 10 12 12 12 8 Collagen triple helix repeat (20 copies) COLFI PF01410.18 RJW62470.1 - 6.8e-47 159.7 0.1 9.5e-47 159.3 0.1 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.24 RJW62470.1 - 2.3e-05 25.0 0.0 4.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 RJW62470.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 RJW62470.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain TMF_TATA_bd PF12325.8 RJW62473.1 - 2.5e-29 101.8 1.3 2.5e-29 101.8 1.3 7.3 2 1 7 9 9 9 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 RJW62473.1 - 1.5e-07 31.3 14.8 1.5e-07 31.3 14.8 8.0 4 2 6 10 10 10 1 TATA element modulatory factor 1 DNA binding DDE_Tnp_1_3 PF13612.6 RJW62473.1 - 0.072 13.1 0.9 0.18 11.8 0.9 1.7 1 0 0 1 1 1 0 Transposase DDE domain Apc13p PF05839.11 RJW62473.1 - 0.27 11.5 5.2 0.072 13.3 0.7 2.5 2 0 0 2 2 2 0 Apc13p protein HU-CCDC81_bac_2 PF18175.1 RJW62473.1 - 0.83 9.6 3.7 9.4 6.2 0.2 3.8 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 HALZ PF02183.18 RJW62473.1 - 5.9 7.2 49.6 0.24 11.6 0.4 7.9 8 1 1 9 9 9 0 Homeobox associated leucine zipper Bromodomain PF00439.25 RJW62474.1 - 1.1e-16 60.7 0.0 2e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain AAA_6 PF12774.7 RJW62475.1 - 1.1e-161 537.3 0.0 2.4e-159 529.6 0.0 3.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW62475.1 - 1.2e-144 482.3 6.3 1.2e-144 482.3 6.3 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RJW62475.1 - 4.8e-119 397.1 0.1 1.2e-118 395.8 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RJW62475.1 - 1.8e-101 338.8 0.3 4.9e-101 337.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RJW62475.1 - 5.6e-91 303.5 3.3 9.7e-90 299.5 0.0 3.8 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 RJW62475.1 - 1.7e-80 268.8 0.1 2.4e-76 255.3 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RJW62475.1 - 9.4e-55 184.9 0.0 2.8e-54 183.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RJW62475.1 - 3.1e-46 158.0 4.2 5.5e-46 157.2 4.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RJW62475.1 - 1e-44 151.4 0.0 9.3e-44 148.3 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 RJW62475.1 - 1.6e-30 105.8 0.3 8.3e-30 103.5 0.2 2.5 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RJW62475.1 - 1.1e-20 74.0 0.1 3.2e-06 27.2 0.0 6.5 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RJW62475.1 - 1.2e-20 73.6 0.0 8.7e-20 70.8 0.0 2.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RJW62475.1 - 3.4e-07 30.6 3.8 0.13 12.6 0.0 5.4 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.6 RJW62475.1 - 4.2e-06 27.2 0.3 9 6.6 0.0 5.9 6 0 0 6 6 5 0 AAA ATPase domain T2SSE PF00437.20 RJW62475.1 - 0.00025 20.2 0.0 0.34 9.9 0.0 3.3 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA PF00004.29 RJW62475.1 - 0.00025 21.5 6.1 1.6 9.2 0.0 5.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 RJW62475.1 - 0.00041 20.4 2.3 0.69 9.9 0.1 3.3 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.6 RJW62475.1 - 0.00047 20.7 0.2 0.25 11.9 0.0 4.4 5 0 0 5 5 3 1 AAA domain Mg_chelatase PF01078.21 RJW62475.1 - 0.0013 18.2 0.0 0.67 9.3 0.0 2.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DEAD PF00270.29 RJW62475.1 - 0.0028 17.4 0.0 8.5 6.1 0.0 3.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_30 PF13604.6 RJW62475.1 - 0.014 15.1 0.2 20 4.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 RJW62475.1 - 0.017 15.5 0.0 74 3.8 0.0 3.9 3 0 0 3 3 3 0 RNA helicase DUF853 PF05872.12 RJW62475.1 - 0.054 12.1 0.6 7.4 5.0 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.6 RJW62475.1 - 0.092 12.9 0.1 39 4.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 RJW62475.1 - 0.36 10.3 2.5 3.3 7.1 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein AAA_24 PF13479.6 RJW62475.1 - 1.2 8.8 3.6 80 2.9 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 RJW62475.1 - 1.8 8.9 9.6 2.2 8.6 0.0 4.0 4 0 0 4 4 3 0 AAA domain WD40 PF00400.32 RJW62477.1 - 6.3e-27 93.3 16.2 1.9e-06 28.5 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW62477.1 - 2.4e-14 53.4 3.0 1.2e-05 25.5 0.2 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW62477.1 - 9.5e-05 22.4 0.1 2.8 7.8 0.0 3.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RJW62477.1 - 0.00028 20.0 0.0 0.15 11.0 0.0 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 RJW62477.1 - 0.095 10.7 0.1 4.6 5.1 0.0 2.5 2 0 0 2 2 2 0 IKI3 family RRM_1 PF00076.22 RJW62478.1 - 2.4e-33 113.8 0.0 1.1e-17 63.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW62478.1 - 0.002 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW62478.1 - 0.063 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif WD40 PF00400.32 RJW62481.1 - 1e-40 136.9 24.1 6.4e-08 33.1 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW62481.1 - 1.8e-05 25.0 0.7 2.6 8.4 0.5 4.7 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RJW62481.1 - 0.0051 16.2 0.0 0.74 9.1 0.0 2.5 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 RJW62481.1 - 0.0052 15.5 2.5 6.8 5.2 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 RJW62481.1 - 0.07 13.2 0.1 13 5.9 0.0 3.5 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region RINT1_TIP1 PF04437.13 RJW62482.1 - 1.1e-62 212.6 0.0 6.2e-33 114.4 0.0 2.6 2 0 0 2 2 2 2 RINT-1 / TIP-1 family PhaP_Bmeg PF09602.10 RJW62482.1 - 0.0024 17.8 0.3 0.97 9.4 0.1 2.9 1 1 1 3 3 3 2 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CdvA PF18822.1 RJW62482.1 - 0.052 13.4 1.4 8.2 6.3 0.1 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain HisKA_3 PF07730.13 RJW62482.1 - 0.15 12.6 1.5 8.9 6.9 0.0 3.3 3 0 0 3 3 3 0 Histidine kinase PigN PF04987.14 RJW62484.1 - 8e-63 212.9 37.8 1.2e-62 212.3 37.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 RJW62484.1 - 1.2e-15 58.0 0.0 1.1e-06 28.5 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 RJW62484.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily RE_MamI PF09567.10 RJW62484.1 - 0.14 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 MamI restriction endonuclease RVT_1 PF00078.27 RJW62485.1 - 8.4e-15 54.9 0.2 4.1e-07 29.8 0.0 2.7 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Orthoreo_P17 PF07272.11 RJW62485.1 - 0.0015 18.6 0.9 0.022 14.8 0.1 2.3 2 0 0 2 2 2 1 Orthoreovirus P17 protein UBA_6 PF18039.1 RJW62485.1 - 0.012 15.5 0.0 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain Ras PF00071.22 RJW62486.1 - 1.4e-46 158.1 0.0 1.6e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW62486.1 - 1.3e-21 77.0 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW62486.1 - 1.5e-06 27.8 0.0 1.8e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW62486.1 - 0.0014 18.2 0.0 0.003 17.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 RJW62486.1 - 0.046 13.5 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RT_RNaseH PF17917.1 RJW62488.1 - 1.7e-20 73.2 0.0 2.3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW62488.1 - 2.5e-19 69.2 0.1 3.4e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TPR_10 PF13374.6 RJW62489.1 - 0.0002 21.1 0.0 0.26 11.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW62489.1 - 0.00044 20.5 0.0 0.0023 18.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DivIC PF04977.15 RJW62489.1 - 0.012 15.4 0.8 0.028 14.2 0.8 1.6 1 0 0 1 1 1 0 Septum formation initiator BMP2K_C PF15282.6 RJW62489.1 - 0.052 13.4 0.3 0.052 13.4 0.3 1.7 2 0 0 2 2 2 0 BMP-2-inducible protein kinase C-terminus SET PF00856.28 RJW62490.1 - 3e-11 44.0 0.4 4.9e-10 40.0 0.4 2.4 1 1 0 1 1 1 1 SET domain XPC-binding PF09280.11 RJW62491.1 - 1.1e-19 70.0 10.0 1.7e-19 69.3 10.0 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 RJW62491.1 - 5.8e-19 67.6 1.1 1e-13 50.9 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 RJW62491.1 - 2e-18 65.9 2.4 3.8e-18 65.0 2.4 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RJW62491.1 - 7.7e-05 22.4 2.8 0.00013 21.7 2.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 RJW62491.1 - 0.0009 19.3 0.6 0.0017 18.4 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RJW62491.1 - 0.043 14.3 0.6 0.11 12.9 0.6 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain UBA_3 PF09288.10 RJW62491.1 - 0.069 13.0 0.0 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF1495 PF07381.11 RJW62491.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) DUF2999 PF11212.8 RJW62491.1 - 0.14 12.5 0.6 3.1 8.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) DUF2407 PF10302.9 RJW62491.1 - 0.15 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF3135 PF11333.8 RJW62491.1 - 0.16 12.3 0.2 0.16 12.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) TFIID_20kDa PF03847.13 RJW62492.1 - 1.3e-16 60.8 0.1 2.6e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Exonuc_VII_L PF02601.15 RJW62492.1 - 8.3e-05 22.3 22.9 0.00012 21.7 22.9 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit CBFD_NFYB_HMF PF00808.23 RJW62492.1 - 0.00059 20.1 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAT1 PF09770.9 RJW62492.1 - 0.0012 17.2 58.9 0.0017 16.8 58.9 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 RJW62492.1 - 0.0021 16.9 40.1 0.003 16.4 40.1 1.1 1 0 0 1 1 1 1 Presenilin Histone PF00125.24 RJW62492.1 - 0.0027 18.0 0.0 0.0027 18.0 0.0 3.2 2 1 0 2 2 1 1 Core histone H2A/H2B/H3/H4 CDC45 PF02724.14 RJW62492.1 - 0.005 15.2 27.9 0.0078 14.6 27.9 1.2 1 0 0 1 1 1 1 CDC45-like protein Macoilin PF09726.9 RJW62492.1 - 0.011 14.4 21.9 0.014 14.0 21.9 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 RJW62492.1 - 0.059 13.3 28.9 0.089 12.7 28.9 1.2 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 RJW62492.1 - 0.12 9.4 42.4 0.17 9.0 42.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCSAP PF15748.5 RJW62492.1 - 0.33 11.1 44.6 0.54 10.4 44.6 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4746 PF15928.5 RJW62492.1 - 0.58 9.5 27.3 1 8.7 27.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPP4R2 PF09184.11 RJW62492.1 - 0.79 9.3 20.9 1.5 8.4 20.9 1.4 1 0 0 1 1 1 0 PPP4R2 AUX_IAA PF02309.16 RJW62492.1 - 0.83 9.5 21.2 1.4 8.7 21.2 1.4 1 0 0 1 1 1 0 AUX/IAA family Peptidase_S64 PF08192.11 RJW62492.1 - 0.9 8.0 28.4 1.2 7.5 28.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 RR_TM4-6 PF06459.12 RJW62492.1 - 0.94 9.2 39.7 1.5 8.6 39.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 RJW62492.1 - 1.2 7.5 16.2 2 6.7 16.2 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDK5_activator PF03261.15 RJW62492.1 - 2.2 7.7 29.0 3.4 7.1 29.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF572 PF04502.13 RJW62492.1 - 2.6 7.6 33.0 4.3 6.9 33.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lin-8 PF03353.15 RJW62492.1 - 3.7 7.0 48.7 6.1 6.3 48.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF966 PF06136.13 RJW62492.1 - 4.1 7.0 30.9 6.1 6.4 30.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Membralin PF09746.9 RJW62492.1 - 4.6 6.2 24.3 7.2 5.5 24.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein GAGA_bind PF06217.12 RJW62492.1 - 5 7.3 29.6 8.5 6.6 29.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Caldesmon PF02029.15 RJW62492.1 - 7.8 5.1 39.6 11 4.6 39.6 1.1 1 0 0 1 1 1 0 Caldesmon Asp-B-Hydro_N PF05279.11 RJW62492.1 - 9.5 6.2 30.0 15 5.6 30.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Rhodanese PF00581.20 RJW62493.1 - 4.9e-09 36.7 0.0 1.3e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain DnaJ PF00226.31 RJW62494.1 - 1.7e-06 28.0 0.0 3.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain PNP_UDP_1 PF01048.20 RJW62496.1 - 7.5e-46 156.3 0.1 9e-46 156.0 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 RJW62498.1 - 5.3e-47 160.0 0.3 6e-47 159.9 0.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily ICMT PF04140.14 RJW62498.1 - 0.084 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ACC_epsilon PF13822.6 RJW62499.1 - 0.19 12.5 1.1 0.33 11.6 1.1 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit DUF913 PF06025.12 RJW62499.1 - 6.8 5.6 16.1 2.8e+02 0.3 16.1 2.2 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) zf-H2C2_2 PF13465.6 RJW62500.1 - 7.2e-25 86.3 45.7 7.7e-07 29.3 2.1 6.8 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 RJW62500.1 - 4.2e-18 64.7 56.6 0.0063 16.9 6.2 6.8 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW62500.1 - 3.3e-13 49.3 53.1 0.00076 20.1 0.2 6.8 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW62500.1 - 5.8e-07 29.6 41.9 0.01 16.1 2.2 6.5 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW62500.1 - 0.0019 18.2 2.2 0.0019 18.2 2.2 7.2 7 0 0 7 7 7 3 C2H2-type zinc finger zf_UBZ PF18439.1 RJW62500.1 - 0.0054 16.3 29.3 0.75 9.4 0.3 6.5 6 0 0 6 6 6 4 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 RJW62500.1 - 0.018 15.4 5.0 0.018 15.4 5.0 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 RJW62500.1 - 0.047 13.8 25.9 1.8 8.8 4.6 5.9 4 2 2 6 6 6 0 Zinc ribbon domain XPA_N PF01286.18 RJW62500.1 - 0.38 10.8 22.1 5.4 7.2 0.0 6.1 6 0 0 6 6 6 0 XPA protein N-terminal zinc_ribbon_15 PF17032.5 RJW62500.1 - 3.4 8.5 24.2 12 6.7 2.6 4.5 2 2 1 3 3 3 0 zinc-ribbon family zinc_ribbon_4 PF13717.6 RJW62500.1 - 6.8 6.7 24.2 14 5.7 0.1 5.4 4 1 0 4 4 4 0 zinc-ribbon domain Peptidase_S8 PF00082.22 RJW62502.1 - 3.6e-47 161.1 1.7 4.6e-47 160.7 1.7 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 RJW62502.1 - 4e-22 78.0 0.0 6.6e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 RJW62502.1 - 5.9e-20 71.8 0.3 1.1e-19 71.0 0.3 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Vg_Tdu PF07545.14 RJW62503.1 - 0.016 15.0 2.4 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Vestigial/Tondu family NTF2 PF02136.20 RJW62506.1 - 7.8e-15 55.5 0.2 1e-14 55.1 0.2 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 RJW62506.1 - 0.00042 20.7 0.0 0.00058 20.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) 2-oxoacid_dh PF00198.23 RJW62507.1 - 1.2e-65 221.3 0.1 1.4e-65 221.0 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RJW62507.1 - 5.7e-12 45.3 1.5 1.9e-11 43.6 1.5 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 RJW62507.1 - 3.3e-08 33.7 0.1 8.2e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain PYNP_C PF07831.13 RJW62507.1 - 0.023 14.3 0.3 0.75 9.5 0.1 2.3 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain IF-2B PF01008.17 RJW62508.1 - 9.5e-53 179.2 0.0 1.2e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cadherin_3 PF16184.5 RJW62510.1 - 2.6e-40 136.9 10.2 1.9e-06 27.9 0.0 10.8 9 1 0 9 9 9 8 Cadherin-like DUF4514 PF14986.6 RJW62510.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) DUF4293 PF14126.6 RJW62511.1 - 0.044 14.0 0.9 0.11 12.7 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) PNP_UDP_1 PF01048.20 RJW62512.1 - 5.6e-42 143.6 0.1 6.1e-42 143.5 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily RVT_1 PF00078.27 RJW62514.1 - 2e-46 158.3 0.0 3.8e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH PF00169.29 RJW62514.1 - 6.4e-18 65.2 0.3 1.3e-09 38.5 0.1 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RJW62514.1 - 2.5e-06 27.9 0.7 0.00061 20.2 0.7 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain ArfGap PF01412.18 RJW62514.1 - 0.0029 17.7 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH_8 PF15409.6 RJW62514.1 - 0.0071 16.6 0.4 0.97 9.8 0.0 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain T6SS_TssG PF06996.11 RJW62515.1 - 0.054 12.7 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion, TssG SNF2_N PF00176.23 RJW62516.1 - 2.3e-73 246.9 1.9 2.3e-73 246.9 1.9 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 RJW62516.1 - 1.6e-21 76.2 0.2 7.7e-21 74.0 0.2 2.2 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 RJW62516.1 - 6.3e-20 71.6 0.0 3e-19 69.4 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 RJW62516.1 - 2e-15 56.9 13.9 2e-15 56.9 13.9 4.2 4 0 0 4 4 4 1 HSA ResIII PF04851.15 RJW62516.1 - 7.4e-13 48.9 0.0 3.7e-12 46.6 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BRK PF07533.16 RJW62516.1 - 1.3e-11 43.9 0.1 2.7e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 BRK domain QLQ PF08880.11 RJW62516.1 - 3.7e-10 39.4 0.8 9.6e-10 38.1 0.8 1.7 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 RJW62516.1 - 3.1e-09 37.3 4.4 3.1e-09 37.3 4.4 5.4 6 1 0 7 7 7 1 Snf2-ATP coupling, chromatin remodelling complex DEAD PF00270.29 RJW62516.1 - 3.9e-05 23.5 0.0 9.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Folate_rec PF03024.14 RJW62517.1 - 0.11 12.4 0.0 14 5.5 0.0 2.0 1 1 0 2 2 2 0 Folate receptor family TEP1_N PF05386.11 RJW62517.1 - 0.19 11.4 0.0 24 4.6 0.0 2.2 2 0 0 2 2 2 0 TEP1 N-terminal domain DUF2043 PF09740.9 RJW62517.1 - 0.2 12.4 0.0 25 5.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) Phospholip_A2_2 PF05826.12 RJW62518.1 - 6.4e-35 119.3 2.0 1.1e-34 118.5 2.0 1.4 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 RJW62518.1 - 0.013 15.9 9.9 0.19 12.2 8.0 2.5 1 1 0 1 1 1 0 Phospholipase A2 MFS_1 PF07690.16 RJW62519.1 - 4.2e-27 95.0 22.7 1.6e-22 79.9 3.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 RJW62519.1 - 0.97 9.3 4.2 0.63 9.8 0.5 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term AIP3 PF03915.13 RJW62521.1 - 7.7e-15 54.9 6.1 1.4e-14 54.0 6.1 1.4 1 1 0 1 1 1 1 Actin interacting protein 3 SUIM_assoc PF16619.5 RJW62521.1 - 0.0082 16.2 5.6 0.041 14.0 5.6 2.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Syntaxin-6_N PF09177.11 RJW62521.1 - 0.014 16.0 1.0 0.053 14.1 1.0 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF2959 PF11172.8 RJW62521.1 - 0.12 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Spc7 PF08317.11 RJW62521.1 - 0.52 9.1 4.2 0.41 9.5 0.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG7_N PF16420.5 RJW62522.1 - 1.5e-73 248.1 0.2 1.9e-73 247.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 RJW62522.1 - 3.9e-41 141.0 0.0 8e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 RJW62522.1 - 0.019 15.1 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RecR PF02132.15 RJW62524.1 - 2 8.0 5.6 0.63 9.7 2.5 1.8 2 0 0 2 2 2 0 RecR protein EntA_Immun PF08951.10 RJW62525.1 - 0.014 15.7 0.2 0.032 14.6 0.2 1.6 1 0 0 1 1 1 0 Enterocin A Immunity DUF1690 PF07956.11 RJW62527.1 - 0.2 12.1 0.0 0.41 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) RVT_1 PF00078.27 RJW62531.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0489 PF12640.7 RJW62532.1 - 2.7e-13 50.5 0.7 1.3e-12 48.3 0.6 2.2 2 1 0 2 2 2 1 UPF0489 domain I-set PF07679.16 RJW62533.1 - 0.0019 18.2 0.0 0.006 16.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW62533.1 - 0.0033 18.0 5.2 0.012 16.2 0.4 2.9 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 RJW62533.1 - 0.0059 16.9 1.7 0.22 11.9 0.1 2.8 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 RJW62533.1 - 0.022 14.8 0.0 0.96 9.6 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain ig PF00047.25 RJW62533.1 - 0.036 14.2 3.2 2.8 8.2 0.6 2.9 2 1 0 2 2 2 0 Immunoglobulin domain V-set PF07686.17 RJW62533.1 - 0.039 14.1 4.0 0.28 11.4 0.8 2.9 2 1 0 2 2 2 0 Immunoglobulin V-set domain L_HMGIC_fpl PF10242.9 RJW62533.1 - 0.09 13.0 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein Cas_Cmr3 PF09700.10 RJW62533.1 - 0.1 12.0 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) Pkinase PF00069.25 RJW62534.1 - 1.2e-72 244.5 0.0 1.5e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW62534.1 - 2.5e-32 112.2 0.0 3.4e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 RJW62534.1 - 9.3e-13 48.3 0.0 2.3e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 RJW62534.1 - 2.5e-06 27.0 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RJW62534.1 - 0.00071 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 RJW62534.1 - 0.0017 17.4 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 RJW62534.1 - 0.045 12.5 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RJW62534.1 - 0.076 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW62534.1 - 0.082 11.8 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain zf-CCHC_3 PF13917.6 RJW62535.1 - 4.3e-11 42.6 10.4 1.1e-10 41.3 10.4 1.8 1 1 0 1 1 1 1 Zinc knuckle Polyoma_coat2 PF00761.20 RJW62535.1 - 0.11 12.2 0.2 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein zf-CCHC_2 PF13696.6 RJW62535.1 - 0.89 9.4 4.3 4.8 7.1 2.0 2.3 2 0 0 2 2 2 0 Zinc knuckle Peroxin-3 PF04882.12 RJW62535.1 - 5.3 5.9 21.8 6.2 5.7 21.8 1.0 1 0 0 1 1 1 0 Peroxin-3 Macoilin PF09726.9 RJW62535.1 - 6.9 5.1 22.9 7.2 5.0 22.9 1.1 1 0 0 1 1 1 0 Macoilin family Raftlin PF15250.6 RJW62535.1 - 9.1 4.9 12.9 9.3 4.9 12.9 1.0 1 0 0 1 1 1 0 Raftlin Peptidase_M8 PF01457.16 RJW62536.1 - 1.5e-17 63.5 0.1 6.3e-17 61.4 0.1 1.7 1 1 0 1 1 1 1 Leishmanolysin BSP_II PF05432.11 RJW62537.1 - 2.5 7.7 10.5 2.9 7.5 10.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PAX PF00292.18 RJW62538.1 - 6.4e-68 226.4 0.5 1.4e-67 225.3 0.5 1.6 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 RJW62538.1 - 1.5e-21 76.0 2.3 3.8e-21 74.7 2.3 1.8 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 RJW62538.1 - 0.0009 19.0 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 RJW62538.1 - 0.035 13.7 0.0 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 InsA C-terminal domain Homeobox_KN PF05920.11 RJW62538.1 - 0.047 13.6 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Homeobox KN domain HTH_28 PF13518.6 RJW62538.1 - 0.1 12.7 0.1 0.86 9.8 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Zn_peptidase_2 PF04298.12 RJW62538.1 - 0.36 10.2 2.1 0.83 9.0 2.1 1.5 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF4148 PF13663.6 RJW62538.1 - 2.9 8.2 5.9 29 5.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) K_channel_TID PF07941.11 RJW62538.1 - 3.3 8.2 9.8 5 7.7 0.6 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Tetraspanin PF00335.20 RJW62541.1 - 1.5e-37 129.6 18.6 1.7e-37 129.4 18.6 1.0 1 0 0 1 1 1 1 Tetraspanin family 7tm_1 PF00001.21 RJW62544.1 - 1.1e-22 80.7 11.0 3.4e-22 79.0 11.0 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2567 PF10821.8 RJW62544.1 - 0.62 10.1 6.7 0.14 12.3 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) DUF4834 PF16118.5 RJW62544.1 - 1.8 9.5 4.7 1.6 9.8 1.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) OTT_1508_deam PF14441.6 RJW62545.1 - 0.65 10.0 3.3 1.4 8.9 0.3 2.5 2 0 0 2 2 2 0 OTT_1508-like deaminase TIM PF00121.18 RJW62547.1 - 3.9e-90 301.5 0.0 4.4e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase I-set PF07679.16 RJW62549.1 - 8.3e-34 115.5 0.0 2.6e-13 49.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW62549.1 - 5.8e-24 84.5 0.0 2.5e-09 37.6 0.0 4.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RJW62549.1 - 3.9e-15 56.0 0.0 1.9e-06 28.1 0.1 4.0 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RJW62549.1 - 1.2e-09 38.2 0.0 3.1e-05 24.1 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain BiPBP_C PF06832.12 RJW62549.1 - 2.3e-07 30.8 0.0 0.023 14.8 0.0 4.1 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family V-set PF07686.17 RJW62549.1 - 4.7e-05 23.5 0.4 1.4 9.1 0.3 4.4 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 RJW62549.1 - 0.00011 22.2 0.0 0.11 12.6 0.1 3.7 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 RJW62549.1 - 0.0088 16.4 0.0 2.1 8.8 0.0 3.2 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Pheromone PF08015.11 RJW62549.1 - 3.8 8.6 5.9 2.1 9.5 1.3 3.2 2 0 0 2 2 2 0 Fungal mating-type pheromone TPR_2 PF07719.17 RJW62550.1 - 3.7e-08 32.9 1.6 0.001 19.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RJW62550.1 - 4.8e-08 32.5 3.1 0.039 13.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RJW62550.1 - 1.9e-05 24.7 0.4 8.7e-05 22.6 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RJW62550.1 - 0.00026 21.0 0.1 0.027 14.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RJW62550.1 - 0.0011 19.4 0.2 0.0034 17.9 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Synaphin PF05835.12 RJW62550.1 - 0.0026 18.0 0.4 0.0078 16.5 0.4 1.7 1 0 0 1 1 1 1 Synaphin protein TPR_14 PF13428.6 RJW62550.1 - 0.0044 17.7 1.6 0.024 15.4 0.4 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RJW62550.1 - 0.034 13.9 0.4 0.083 12.6 0.0 1.8 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 RJW62550.1 - 0.035 14.8 0.1 0.035 14.8 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW62550.1 - 0.041 13.9 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 RJW62550.1 - 0.05 13.8 0.1 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF PF00209.18 RJW62553.1 - 3.8e-20 72.1 37.3 2.6e-19 69.3 26.0 2.1 1 1 0 2 2 2 2 Sodium:neurotransmitter symporter family Erf4 PF10256.9 RJW62554.1 - 2e-11 44.0 0.0 2.6e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family GOLGA2L5 PF15070.6 RJW62555.1 - 2.8e-24 85.7 55.4 2.8e-24 85.7 55.4 3.2 1 1 2 3 3 3 1 Putative golgin subfamily A member 2-like protein 5 DUF1722 PF08349.11 RJW62555.1 - 0.0087 16.3 2.8 0.28 11.5 0.4 3.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1722) EF-hand_7 PF13499.6 RJW62558.1 - 2.2e-18 66.4 1.2 4.9e-08 33.3 0.1 4.2 3 3 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RJW62558.1 - 6.9e-15 53.4 4.8 5.6e-08 31.8 0.1 4.8 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 RJW62558.1 - 7.1e-15 53.6 1.2 2.5e-07 30.1 0.1 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 RJW62558.1 - 1.1e-13 50.8 0.7 0.00013 21.8 0.0 5.5 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW62558.1 - 8.6e-12 44.0 0.8 0.00012 21.4 0.1 3.6 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 RJW62558.1 - 0.0011 18.9 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RJW62558.1 - 0.12 12.7 0.0 2.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region WD40 PF00400.32 RJW62559.1 - 2.8e-16 59.6 13.5 6.4e-05 23.6 0.4 8.4 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW62559.1 - 0.0007 19.8 0.3 1.7 9.0 0.0 5.1 6 1 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain E2R135 PF11570.8 RJW62559.1 - 0.0066 16.7 6.1 0.0066 16.7 6.1 2.2 2 0 0 2 2 2 1 Coiled-coil receptor-binding R-domain of colicin E2 WD40_like PF17005.5 RJW62559.1 - 0.048 13.0 0.6 3 7.1 0.0 3.4 3 0 0 3 3 3 0 WD40-like domain DUF4596 PF15363.6 RJW62559.1 - 0.051 13.8 0.0 4 7.7 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4596) Cytotoxic PF09000.10 RJW62559.1 - 0.13 12.6 1.5 2.2 8.7 0.0 3.3 3 0 0 3 3 3 0 Cytotoxic ERG4_ERG24 PF01222.17 RJW62560.1 - 7.5e-63 212.8 6.5 1.6e-62 211.7 6.5 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 RJW62560.1 - 2.4e-06 27.3 0.2 5.8e-06 26.0 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 RJW62560.1 - 0.0057 17.0 0.0 0.0057 17.0 0.0 2.6 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 RJW62560.1 - 0.015 15.7 0.3 0.16 12.4 0.0 2.7 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NVEALA PF14055.6 RJW62560.1 - 0.3 11.1 2.5 0.28 11.2 0.2 2.1 2 0 0 2 2 2 0 NVEALA protein DAO PF01266.24 RJW62562.1 - 1.2e-60 206.0 0.0 1.5e-60 205.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RJW62562.1 - 0.00012 22.3 0.3 0.00026 21.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 RJW62562.1 - 0.0072 14.9 0.0 0.83 8.1 0.0 2.3 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 RJW62562.1 - 0.034 13.4 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 RJW62562.1 - 0.076 12.2 0.1 9.4 5.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 RJW62562.1 - 0.12 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Telomere_reg-2 PF10193.9 RJW62563.1 - 8.1e-20 71.3 0.1 3.7e-19 69.2 0.0 2.2 2 0 0 2 2 2 1 Telomere length regulation protein Asp PF00026.23 RJW62564.1 - 6.5e-30 104.6 0.0 7.3e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW62564.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 RJW62564.1 - 0.057 14.0 0.0 3.5 8.3 0.0 2.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease eIF-1a PF01176.19 RJW62565.1 - 2e-21 75.6 0.1 3.5e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ATHILA PF03078.15 RJW62565.1 - 0.13 11.1 1.5 0.17 10.7 1.5 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family CENP-B_dimeris PF09026.10 RJW62565.1 - 0.61 10.5 17.0 1.4 9.4 17.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 RJW62565.1 - 0.85 7.8 11.3 1 7.5 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RJW62565.1 - 1.2 7.2 15.8 1.4 6.9 15.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 RJW62565.1 - 2.5 7.1 17.4 3.5 6.7 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WVELL PF14043.6 RJW62570.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 WVELL protein VPS13_mid_rpt PF16910.5 RJW62571.1 - 1.5e-76 257.0 17.0 6.8e-67 225.3 0.0 6.5 7 0 0 7 7 7 3 Repeating coiled region of VPS13 VPS13 PF16908.5 RJW62571.1 - 1.2e-32 113.6 1.5 2e-30 106.4 0.9 3.4 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal AHSP PF09236.10 RJW62571.1 - 0.35 11.3 2.9 4.8 7.7 0.3 3.1 3 0 0 3 3 3 0 Alpha-haemoglobin stabilising protein DUF755 PF05501.11 RJW62571.1 - 6.4 7.1 11.2 20 5.5 10.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) CCDC53 PF10152.9 RJW62571.1 - 9.6 6.6 9.2 0.84 10.0 0.2 3.4 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex RT_RNaseH_2 PF17919.1 RJW62572.1 - 1e-08 35.1 0.0 2.4e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW62572.1 - 1.7e-06 28.3 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SelB-wing_2 PF09106.11 RJW62572.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix adh_short_C2 PF13561.6 RJW62575.1 - 3.2e-08 33.4 0.0 3.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RJW62575.1 - 1.5e-07 31.0 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Ets PF00178.22 RJW62576.1 - 2.2e-32 111.3 1.0 2.2e-32 111.3 1.0 1.8 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 RJW62576.1 - 1.3e-13 50.7 0.1 2.8e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Tubulin-binding PF00418.19 RJW62579.1 - 5.2e-65 215.1 28.9 5.5e-12 45.5 0.3 6.6 7 0 0 7 7 7 6 Tau and MAP protein, tubulin-binding repeat F5_F8_type_C PF00754.25 RJW62580.1 - 1.7e-09 37.8 0.0 9.7e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain CBM26 PF16738.5 RJW62580.1 - 0.0053 17.0 0.7 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 Starch-binding module 26 LapA_dom PF06305.11 RJW62580.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 RJW62581.1 - 1.6e-44 152.3 0.0 3.1e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW62581.1 - 6.8e-31 107.5 0.0 1.3e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW62581.1 - 4.3e-06 26.3 0.0 7.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RJW62581.1 - 0.0023 16.8 0.0 0.0023 16.8 0.0 3.0 3 0 0 3 3 3 1 Fungal protein kinase RVT_1 PF00078.27 RJW62581.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RasGAP_C PF03836.15 RJW62581.1 - 0.3 11.2 3.9 0.97 9.6 3.9 1.9 1 0 0 1 1 1 0 RasGAP C-terminus ATP-synt_C PF00137.21 RJW62582.1 - 0.065 13.6 0.0 0.097 13.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase subunit C MFS_1 PF07690.16 RJW62583.1 - 3e-31 108.7 24.1 3e-31 108.7 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.27 RJW62584.1 - 8.7e-45 152.9 0.0 1.4e-44 152.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW62584.1 - 5.7e-07 29.4 0.0 1.6e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW62584.1 - 6.7e-07 29.1 1.1 1.8e-06 27.7 0.4 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Complex1_LYR PF05347.15 RJW62584.1 - 1.8e-05 24.7 0.2 1.8e-05 24.7 0.2 2.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) CUE PF02845.16 RJW62584.1 - 0.032 13.9 0.2 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 CUE domain DMA PF03474.14 RJW62584.1 - 0.11 12.1 1.6 0.15 11.7 0.1 2.0 2 0 0 2 2 2 0 DMRTA motif SgrR_N PF12793.7 RJW62585.1 - 0.11 12.8 3.2 0.074 13.3 0.9 1.9 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term p31comet PF06581.12 RJW62586.1 - 0.0025 17.0 0.0 0.05 12.8 0.0 2.2 2 0 0 2 2 2 2 Mad1 and Cdc20-bound-Mad2 binding PP2C PF00481.21 RJW62587.1 - 1.4e-73 247.8 0.0 1.7e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 RJW62587.1 - 1.6e-18 66.9 0.0 3.6e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 RJW62587.1 - 0.0011 18.6 0.0 0.0029 17.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RJW62587.1 - 0.003 17.5 0.1 0.053 13.4 0.1 2.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Mob_synth_C PF06463.13 RJW62589.1 - 6.3e-32 110.2 0.0 1.1e-31 109.5 0.0 1.5 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 RJW62589.1 - 3.4e-09 37.3 0.0 5.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily ATE_C PF04377.15 RJW62590.1 - 2.5e-48 164.1 1.4 4.2e-48 163.4 1.4 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 RJW62590.1 - 8.7e-14 51.7 2.6 2.3e-13 50.3 2.6 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus RRM_1 PF00076.22 RJW62594.1 - 6.3e-18 64.4 0.0 1.2e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW62594.1 - 0.0008 19.0 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RJW62594.1 - 0.06 13.4 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Limkain b1 EMP70 PF02990.16 RJW62595.1 - 8.1e-148 493.3 16.3 1.2e-147 492.8 16.3 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 PsbM PF05151.12 RJW62595.1 - 1.5 8.7 7.8 0.82 9.5 3.0 2.8 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) Ig_3 PF13927.6 RJW62597.1 - 0.0014 19.1 0.0 0.0024 18.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Adeno_E3_CR2 PF02439.15 RJW62597.1 - 0.019 14.7 0.1 0.019 14.7 0.1 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Ion_trans PF00520.31 RJW62597.1 - 0.033 13.4 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 Ion transport protein I-set PF07679.16 RJW62597.1 - 0.069 13.2 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW62597.1 - 0.096 13.0 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin domain JHY PF15261.6 RJW62598.1 - 8.8e-07 29.7 21.2 1.8e-05 25.5 0.1 3.4 3 0 0 3 3 3 2 Jhy protein TIM PF00121.18 RJW62600.1 - 2.9e-74 249.5 0.1 3.3e-74 249.3 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase RVT_1 PF00078.27 RJW62601.1 - 1.4e-33 116.3 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Annexin PF00191.20 RJW62604.1 - 2.8e-55 184.3 6.9 3.4e-24 84.7 0.4 4.2 4 0 0 4 4 4 4 Annexin RVT_1 PF00078.27 RJW62605.1 - 0.0005 19.6 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AMPK1_CBM PF16561.5 RJW62609.1 - 9.8e-30 102.6 0.3 2.8e-29 101.2 0.4 1.7 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 RJW62609.1 - 1.2e-23 83.2 1.7 1.2e-23 83.2 1.7 2.0 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 RJW62609.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Misat_Tub_SegII PF10644.9 RJW62610.1 - 6.4e-11 42.6 0.0 1.8e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RJW62610.1 - 1e-05 25.3 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 RJW62610.1 - 0.0033 17.6 0.0 0.97 9.6 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Ras PF00071.22 RJW62611.1 - 2.3e-52 176.8 0.0 2.7e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW62611.1 - 2e-30 105.5 0.0 3.7e-30 104.6 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW62611.1 - 3.3e-08 33.2 0.0 4.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RJW62611.1 - 2.9e-06 27.3 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 RJW62611.1 - 3e-06 26.8 0.0 4.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RJW62611.1 - 2.4e-05 24.4 0.0 3.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RJW62611.1 - 0.0016 18.8 0.0 0.0066 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RJW62611.1 - 0.0052 17.1 0.0 0.0083 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 RJW62611.1 - 0.0069 15.9 0.0 0.06 12.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 RJW62611.1 - 0.01 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 RJW62611.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 RJW62611.1 - 0.043 13.0 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 RJW62611.1 - 0.046 14.2 0.0 0.14 12.7 0.0 1.9 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 RJW62611.1 - 0.051 13.5 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 RJW62611.1 - 0.064 12.5 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 Septin cobW PF02492.19 RJW62611.1 - 0.1 12.2 0.0 8.5 5.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 RJW62611.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 RJW62611.1 - 0.18 11.5 0.1 0.38 10.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ERG4_ERG24 PF01222.17 RJW62612.1 - 7.2e-28 97.5 3.0 3.2e-19 69.0 0.2 2.2 2 0 0 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family RVT_1 PF00078.27 RJW62613.1 - 4.4e-09 36.2 0.0 5.5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_2b PF00587.25 RJW62614.1 - 2.4e-16 60.2 0.0 4.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TPR_2 PF07719.17 RJW62614.1 - 5.4e-12 44.8 7.9 4.4e-05 23.3 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 RJW62614.1 - 7.3e-10 38.2 5.6 0.0017 18.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW62614.1 - 7.7e-08 32.5 0.1 1.3 10.1 0.1 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW62614.1 - 1.7e-07 30.9 3.7 0.11 12.8 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW62614.1 - 1.1e-06 28.8 1.0 0.0022 18.2 0.0 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 RJW62614.1 - 1.2e-05 25.7 0.1 0.2 12.2 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW62614.1 - 1.7e-05 24.9 1.4 0.21 12.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW62614.1 - 7.2e-05 22.5 1.1 0.8 9.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RJW62614.1 - 0.00038 20.1 0.3 0.56 9.9 0.0 4.3 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 RJW62614.1 - 0.00057 20.5 0.3 0.019 15.6 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW62614.1 - 0.0011 19.1 0.4 0.025 14.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW62614.1 - 0.0035 17.5 5.4 0.015 15.5 0.9 4.0 2 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RJW62614.1 - 0.013 14.8 0.2 1.8 7.7 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.20 RJW62614.1 - 0.13 12.1 0.4 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_10 PF13374.6 RJW62614.1 - 0.22 11.4 2.4 1.5 8.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 RJW62614.1 - 0.24 11.7 1.5 57 4.3 0.0 4.4 4 0 0 4 4 4 0 PPR repeat DNA_pol_B PF00136.21 RJW62615.1 - 3.3e-146 487.6 0.0 4.3e-146 487.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 RJW62615.1 - 3.3e-77 259.9 0.0 5.9e-77 259.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 RJW62615.1 - 1.2e-18 67.4 5.8 2.8e-18 66.2 5.8 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 RJW62615.1 - 0.0016 17.4 0.6 0.0029 16.6 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 RJW62615.1 - 0.0041 16.8 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 RJW62615.1 - 3.7 7.5 5.0 23 4.9 5.0 2.1 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LRR_6 PF13516.6 RJW62616.1 - 7.9e-17 59.8 14.7 4.9e-05 23.1 0.1 7.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 RJW62616.1 - 2.9e-05 24.3 2.1 12 6.5 0.0 4.7 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW62616.1 - 0.0056 17.1 6.9 41 5.3 0.9 5.9 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 RJW62616.1 - 0.36 10.6 2.4 24 4.8 0.1 3.9 3 2 1 5 5 5 0 Leucine rich repeat RVT_1 PF00078.27 RJW62617.1 - 2e-38 132.1 0.0 3.8e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPAP1_C PF08620.10 RJW62617.1 - 1.6e-24 85.8 0.2 5.7e-24 84.0 0.2 2.0 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 RJW62617.1 - 2.4e-13 49.6 4.5 5.6e-13 48.4 4.5 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal Adeno_E3A PF05248.12 RJW62618.1 - 0.021 14.8 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E3A Mfa1 PF17445.2 RJW62619.1 - 0.09 12.8 1.0 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Mating factor A1 Solute_trans_a PF03619.16 RJW62620.1 - 3.2e-86 289.1 23.1 3.9e-86 288.9 23.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha RVT_1 PF00078.27 RJW62621.1 - 8.6e-14 51.6 0.0 3.3e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Molybdopterin PF00384.22 RJW62621.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin oxidoreductase ABC_tran_CTD PF16326.5 RJW62621.1 - 0.46 10.8 0.0 0.46 10.8 0.0 3.1 3 1 0 4 4 4 0 ABC transporter C-terminal domain Tup_N PF08581.10 RJW62621.1 - 2.7 8.3 5.4 1.1 9.7 0.2 2.6 3 0 0 3 3 3 0 Tup N-terminal CAP PF00188.26 RJW62624.1 - 2.9e-36 125.1 2.2 6.8e-19 69.0 0.4 2.4 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Forkhead PF00250.18 RJW62627.1 - 3.1e-31 107.5 0.1 5.7e-31 106.6 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain WD40 PF00400.32 RJW62629.1 - 8.3e-40 134.0 7.8 5.2e-06 27.1 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat TMEM219 PF14940.6 RJW62629.1 - 1.2e-19 70.9 0.0 1.9e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Transmembrane 219 PRP4 PF08799.11 RJW62629.1 - 3.7e-14 52.0 0.9 7.8e-14 50.9 0.9 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 RJW62629.1 - 2.3e-10 40.6 0.0 0.1 12.9 0.0 6.2 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW62629.1 - 3.9e-07 29.1 0.7 0.28 9.8 0.0 4.2 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RJW62629.1 - 4.8e-07 29.1 0.0 0.42 9.5 0.0 4.8 2 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Pectate_lyase22 PF14583.6 RJW62629.1 - 0.032 12.9 0.0 0.055 12.1 0.0 1.3 1 0 0 1 1 1 0 Oligogalacturonate lyase Nbas_N PF15492.6 RJW62629.1 - 0.037 13.3 0.0 1.7 7.9 0.0 2.5 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF441 PF04284.13 RJW62629.1 - 0.063 13.3 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF441) Sel1 PF08238.12 RJW62630.1 - 1.2e-45 152.9 35.6 3.5e-08 33.9 0.9 11.2 11 0 0 11 11 11 10 Sel1 repeat Ldr_toxin PF13940.6 RJW62630.1 - 0.11 12.6 1.3 0.24 11.5 0.3 2.1 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system TPR_16 PF13432.6 RJW62630.1 - 8.3 7.2 10.1 5.2 7.8 1.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Annexin PF00191.20 RJW62631.1 - 1.6e-74 245.9 5.7 4.8e-23 81.0 0.4 4.8 4 1 0 4 4 4 4 Annexin NCA2 PF08637.10 RJW62631.1 - 0.027 13.6 0.1 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 SAM_Exu PF18609.1 RJW62631.1 - 0.3 11.2 1.1 2.5 8.3 0.1 2.9 3 1 0 3 3 3 0 Exuperantia SAM-like domain MCM PF00493.23 RJW62632.1 - 4.8e-73 245.0 0.0 8.9e-65 217.9 0.0 2.2 2 0 0 2 2 2 2 MCM P-loop domain MCM_lid PF17855.1 RJW62632.1 - 2.7e-24 85.4 2.9 6.2e-24 84.2 2.9 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 RJW62632.1 - 7.6e-22 77.5 0.3 2.8e-21 75.7 0.3 1.9 1 1 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 RJW62632.1 - 5.7e-07 29.1 0.1 0.00012 21.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RJW62632.1 - 4.6e-05 23.4 0.0 8.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RJW62632.1 - 0.0044 16.9 0.0 0.026 14.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW62632.1 - 0.036 14.5 0.8 0.12 12.7 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 RJW62632.1 - 0.073 13.3 0.2 0.31 11.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 RJW62632.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RuvB_N PF05496.12 RJW62632.1 - 0.19 11.5 0.0 0.6 9.8 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Peptidase_U49 PF10463.9 RJW62633.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase U49 RGS12_usC PF16612.5 RJW62633.1 - 0.23 11.9 4.2 0.34 11.4 2.4 2.1 1 1 1 2 2 2 0 C-terminal unstructured region of RGS12 Utp14 PF04615.13 RJW62634.1 - 7.7e-63 213.3 40.8 1.1e-44 153.2 34.6 2.0 1 1 1 2 2 2 2 Utp14 protein MoaC PF01967.21 RJW62635.1 - 3.8e-37 127.4 1.7 3.9e-37 127.4 0.2 1.7 2 0 0 2 2 2 1 MoaC family SNF PF00209.18 RJW62636.1 - 3e-37 128.5 52.2 2.2e-19 69.6 16.6 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family PP2C PF00481.21 RJW62637.1 - 2.8e-24 86.1 0.0 8.7e-24 84.5 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C AAA PF00004.29 RJW62638.1 - 2.7e-30 105.5 0.0 1.6e-29 103.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RJW62638.1 - 2.8e-07 30.9 0.0 2.5e-06 27.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RJW62638.1 - 1.5e-06 28.8 0.0 2.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RJW62638.1 - 2.1e-05 25.0 0.0 0.00011 22.6 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 RJW62638.1 - 7.5e-05 23.0 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RJW62638.1 - 0.00024 20.9 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RJW62638.1 - 0.00038 20.8 0.0 0.0016 18.8 0.0 2.1 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.6 RJW62638.1 - 0.0017 18.4 0.0 0.0046 17.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 RJW62638.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 RJW62638.1 - 0.0018 18.2 0.0 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RJW62638.1 - 0.0019 17.4 0.1 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 RJW62638.1 - 0.0019 17.8 0.1 0.015 14.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RJW62638.1 - 0.0024 17.7 0.0 0.0099 15.6 0.0 2.0 3 0 0 3 3 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 RJW62638.1 - 0.0026 17.7 0.0 0.13 12.1 0.0 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_2 PF07724.14 RJW62638.1 - 0.0028 17.8 0.0 0.014 15.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RJW62638.1 - 0.0035 17.5 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 RJW62638.1 - 0.0037 17.3 0.0 0.0076 16.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.14 RJW62638.1 - 0.0055 16.7 0.0 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 RJW62638.1 - 0.0058 16.4 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 RJW62638.1 - 0.0076 14.9 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 RJW62638.1 - 0.0083 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase NACHT PF05729.12 RJW62638.1 - 0.0084 16.0 0.0 0.025 14.5 0.0 2.0 1 1 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 RJW62638.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 RJW62638.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RJW62638.1 - 0.022 14.3 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 RJW62638.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 RJW62638.1 - 0.031 14.2 0.0 0.084 12.8 0.0 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 RJW62638.1 - 0.038 13.7 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 RJW62638.1 - 0.049 14.0 0.1 0.23 11.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 RJW62638.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain PhoH PF02562.16 RJW62638.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.13 RJW62638.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 RJW62638.1 - 0.19 12.2 0.0 0.41 11.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Kinesin PF00225.23 RJW62639.1 - 1e-96 323.8 0.4 1.8e-96 322.9 0.1 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW62639.1 - 3.4e-26 92.0 0.1 1.2e-25 90.2 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding zf-AN1 PF01428.16 RJW62641.1 - 3.7e-21 75.0 23.0 4.9e-11 42.6 6.6 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 RJW62641.1 - 0.063 13.6 19.6 0.24 11.8 5.5 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain IBR PF01485.21 RJW62641.1 - 0.38 11.0 16.3 1 9.7 3.9 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_5 PF13719.6 RJW62641.1 - 0.7 9.7 8.7 3.7 7.4 0.4 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC5 PF06221.13 RJW62641.1 - 7.6 6.6 13.5 1 9.4 3.9 2.5 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type TMEM132D_C PF15706.5 RJW62644.1 - 8.9e-05 22.2 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4685 PF15737.5 RJW62644.1 - 2.5 8.5 5.3 17 5.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) PH PF00169.29 RJW62645.1 - 1.3e-07 32.1 0.1 2.6e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 PH domain PGG PF13962.6 RJW62647.1 - 0.63 9.9 7.8 0.31 10.9 3.0 2.7 2 1 0 2 2 2 0 Domain of unknown function DCP2 PF05026.13 RJW62648.1 - 1.8e-17 63.4 0.5 4.1e-17 62.3 0.5 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 RJW62648.1 - 4.6e-14 52.6 0.0 1.2e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain RT_RNaseH PF17917.1 RJW62649.1 - 8.3e-29 100.0 0.2 4.1e-28 97.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW62649.1 - 1e-27 96.0 1.5 2.1e-27 95.1 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 RJW62649.1 - 4.7e-19 68.2 0.2 1.2e-18 66.9 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RJW62649.1 - 0.00015 21.9 0.5 0.00047 20.3 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger PNMA PF14893.6 RJW62649.1 - 0.019 14.4 0.0 0.056 12.8 0.0 1.6 1 1 0 1 1 1 0 PNMA Cript PF10235.9 RJW62649.1 - 2.1 9.0 8.1 0.21 12.2 2.1 2.4 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Nup35_RRM PF05172.13 RJW62650.1 - 0.095 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Glyco_hydro_71 PF03659.14 RJW62651.1 - 0.16 10.8 0.3 0.19 10.5 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Cytochrom_B561 PF03188.16 RJW62652.1 - 0.0063 16.7 2.2 0.0063 16.7 2.2 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 RepA1_leader PF08048.12 RJW62652.1 - 0.018 15.3 3.5 0.043 14.1 3.5 1.6 1 0 0 1 1 1 0 Tap RepA1 leader peptide KAP PF05804.12 RJW62653.1 - 6.1e-236 785.0 21.2 1.4e-171 572.2 8.4 2.3 2 1 0 2 2 2 2 Kinesin-associated protein (KAP) Arm PF00514.23 RJW62653.1 - 1.2e-05 25.2 0.1 6.4 7.0 0.0 6.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 RJW62653.1 - 0.021 14.9 4.2 0.25 11.4 0.8 3.5 3 1 0 3 3 3 0 V-ATPase subunit H Imm48 PF15574.6 RJW62653.1 - 0.045 13.5 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Immunity protein 48 RhoGAP PF00620.27 RJW62653.1 - 0.078 12.8 1.6 0.61 9.9 0.2 3.1 3 0 0 3 3 3 0 RhoGAP domain FPL PF09758.9 RJW62653.1 - 1.3 9.0 7.0 0.62 10.1 1.7 2.6 3 0 0 3 3 3 0 Uncharacterised conserved protein Cnd1 PF12717.7 RJW62653.1 - 5.1 7.1 7.6 3 7.9 0.1 3.4 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Kinesin PF00225.23 RJW62654.1 - 1.6e-87 293.6 0.1 1.6e-87 293.6 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW62654.1 - 8.1e-10 38.8 0.1 2e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding NDK PF00334.19 RJW62655.1 - 1.6e-40 138.3 0.0 2.4e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 RJW62655.1 - 4.4e-18 64.7 0.4 7.4e-18 64.0 0.4 1.4 1 0 0 1 1 1 1 Dpy-30 motif Hrs_helical PF12210.8 RJW62656.1 - 2.6e-38 130.5 5.3 2.6e-38 130.5 5.3 2.5 1 1 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE PF01363.21 RJW62656.1 - 2.4e-17 62.8 14.6 4.4e-17 62.0 14.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger VHS PF00790.19 RJW62656.1 - 2e-13 50.4 0.6 1.5e-11 44.3 0.0 2.5 2 0 0 2 2 2 1 VHS domain DZR PF12773.7 RJW62656.1 - 5.8 7.0 11.1 6.7e+02 0.4 11.1 2.8 1 1 0 1 1 1 0 Double zinc ribbon APG6_N PF17675.1 RJW62656.1 - 9.1 6.8 31.5 2.6 8.6 9.9 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-RING_9 PF13901.6 RJW62657.1 - 4.1e-32 111.8 17.0 5.8e-32 111.4 5.2 2.5 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon C1_1 PF00130.22 RJW62657.1 - 1.1e-05 25.2 3.8 1.1e-05 25.2 3.8 4.2 4 0 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Mac PF12464.8 RJW62657.1 - 3.8 7.8 6.5 8 6.8 0.1 3.3 3 0 0 3 3 3 0 Maltose acetyltransferase RVT_1 PF00078.27 RJW62658.1 - 0.14 11.6 0.0 0.75 9.3 0.0 2.1 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 RJW62659.1 - 2.7e-35 121.9 0.0 5.9e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L18 PF17135.4 RJW62659.1 - 8.2e-06 25.3 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Hjc PF01870.18 RJW62659.1 - 0.0082 16.1 0.5 0.022 14.7 0.1 1.9 2 0 0 2 2 2 1 Archaeal holliday junction resolvase (hjc) EIF_2_alpha PF07541.12 RJW62661.1 - 1.4e-31 109.0 0.0 2.7e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 RJW62661.1 - 5.2e-12 45.9 1.2 8.4e-12 45.3 1.2 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RVT_1 PF00078.27 RJW62661.1 - 0.0028 17.2 0.1 0.0051 16.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EXOSC1 PF10447.9 RJW62661.1 - 0.11 13.1 0.2 0.24 12.0 0.2 1.6 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 Pes-10 PF07149.11 RJW62661.1 - 0.74 8.8 4.4 1.3 8.0 4.4 1.3 1 0 0 1 1 1 0 Pes-10 Astro_capsid_p PF12226.8 RJW62661.1 - 3.4 6.7 6.7 5.9 6.0 6.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Frizzled PF01534.17 RJW62662.1 - 1.3e-80 270.9 11.0 2.1e-80 270.2 11.0 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 RJW62662.1 - 9.7e-29 100.2 5.5 1.8e-28 99.4 5.5 1.4 1 0 0 1 1 1 1 Fz domain IQ PF00612.27 RJW62663.1 - 0.1 12.4 3.6 0.27 11.1 3.6 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Aminotran_1_2 PF00155.21 RJW62664.1 - 1.1e-36 126.8 0.0 1.5e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RJW62664.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 RJW62664.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RJW62664.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 RJW62664.1 - 0.028 13.0 0.0 0.041 12.4 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme ICAM_N PF03921.14 RJW62665.1 - 0.11 12.2 0.0 0.58 9.9 0.0 2.0 1 1 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain Acyl_transf_3 PF01757.22 RJW62666.1 - 6.5e-10 38.6 9.3 6.5e-10 38.6 9.3 1.6 2 0 0 2 2 2 1 Acyltransferase family PhoLip_ATPase_C PF16212.5 RJW62666.1 - 0.26 11.0 10.0 0.7 9.6 10.0 1.6 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal Sec1 PF00995.23 RJW62667.1 - 6.1e-56 190.8 0.0 7.5e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_transf_10 PF00852.19 RJW62667.1 - 0.021 14.5 0.2 0.037 13.8 0.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term PhoLip_ATPase_C PF16212.5 RJW62669.1 - 5.9e-55 186.7 21.7 5.9e-55 186.7 21.7 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RJW62669.1 - 2.9e-14 52.5 2.1 2.9e-14 52.5 2.1 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RJW62669.1 - 2.3e-09 37.9 3.4 1.4e-06 28.8 0.6 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RJW62669.1 - 1.8e-08 34.3 0.0 4.2e-07 30.0 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RJW62669.1 - 1.2e-05 24.9 0.0 6.8e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RJW62669.1 - 0.011 15.5 0.1 0.037 13.8 0.1 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 RJW62669.1 - 0.21 12.0 0.5 4.2 7.7 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF3671 PF12420.8 RJW62669.1 - 4.5 7.4 6.9 0.46 10.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function Galactosyl_T PF01762.21 RJW62670.1 - 2.7e-42 144.8 0.0 3.8e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 RJW62670.1 - 3.6e-05 23.3 0.1 9.4e-05 22.0 0.1 1.7 1 1 0 1 1 1 1 Fringe-like Pro-NT_NN PF07421.11 RJW62670.1 - 0.028 14.7 0.6 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor SAPS PF04499.15 RJW62670.1 - 0.1 11.4 7.2 0.13 11.1 7.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 RJW62670.1 - 6.2 6.2 48.6 9.1 5.6 48.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RJW62670.1 - 10 4.2 46.9 15 3.7 46.9 1.1 1 0 0 1 1 1 0 Nop14-like family PhoLip_ATPase_C PF16212.5 RJW62671.1 - 6.5e-55 186.6 22.3 6.5e-55 186.6 22.3 3.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RJW62671.1 - 4.4e-12 45.5 1.6 4.4e-12 45.5 1.6 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RJW62671.1 - 4e-10 40.3 0.7 2e-05 25.0 0.3 3.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RJW62671.1 - 7.8e-05 22.7 0.0 0.00067 19.7 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RJW62671.1 - 0.028 14.2 0.0 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 RJW62671.1 - 0.091 13.1 0.0 0.71 10.2 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RJW62671.1 - 0.31 10.6 2.6 0.8 9.2 0.0 2.7 2 1 0 2 2 2 0 E1-E2 ATPase V_ATPase_I PF01496.19 RJW62672.1 - 0.045 11.7 3.5 0.051 11.5 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 RJW62672.1 - 0.13 10.6 0.1 0.17 10.3 0.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 RJW62672.1 - 0.22 9.8 7.0 0.25 9.6 7.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 RJW62672.1 - 0.75 8.5 6.6 0.91 8.2 6.6 1.1 1 0 0 1 1 1 0 Presenilin ARGLU PF15346.6 RJW62672.1 - 0.83 9.5 26.5 1.2 9.0 26.5 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DDRGK PF09756.9 RJW62672.1 - 1 8.9 17.5 1.4 8.4 17.5 1.2 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 RJW62672.1 - 3.7 7.3 10.1 4.8 6.9 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MDM10 PF12519.8 RJW62672.1 - 4.1 6.2 5.7 5.1 5.8 5.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 AAA_11 PF13086.6 RJW62672.1 - 6.5 6.5 8.7 7.8 6.2 8.7 1.1 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.11 RJW62672.1 - 8.1 4.8 13.7 10 4.5 13.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MULE PF10551.9 RJW62676.1 - 8.7e-15 54.9 0.0 2.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain TNFR_c6 PF00020.18 RJW62678.1 - 9.5e-06 25.9 9.0 9.5e-06 25.9 9.0 5.3 3 1 2 5 5 5 2 TNFR/NGFR cysteine-rich region EGF_CA PF07645.15 RJW62678.1 - 0.0032 17.6 10.6 0.0032 17.6 10.6 3.8 3 1 0 3 3 3 1 Calcium-binding EGF domain hEGF PF12661.7 RJW62678.1 - 8.9 7.1 19.1 0.063 13.9 4.0 3.5 3 0 0 3 3 3 0 Human growth factor-like EGF DUF1759 PF03564.15 RJW62680.1 - 0.0018 18.2 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Dor1 PF04124.12 RJW62680.1 - 0.0041 15.8 0.0 0.0053 15.5 0.0 1.2 1 0 0 1 1 1 1 Dor1-like family Sec1 PF00995.23 RJW62682.1 - 2.5e-18 66.7 0.2 2.6e-18 66.6 0.2 1.0 1 0 0 1 1 1 1 Sec1 family Aminotran_1_2 PF00155.21 RJW62684.1 - 9.1e-07 28.4 0.0 1.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cu_amine_oxid PF01179.20 RJW62685.1 - 7.9e-78 262.2 0.0 1.2e-77 261.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 RJW62685.1 - 0.013 15.3 0.1 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) IFT20 PF14931.6 RJW62686.1 - 3.5e-37 127.2 12.5 4.7e-37 126.8 12.5 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 MCM3AP_GANP PF16769.5 RJW62686.1 - 0.0012 17.2 7.0 0.0014 17.0 7.0 1.1 1 0 0 1 1 1 1 MCM3AP domain of GANP WEMBL PF05701.11 RJW62686.1 - 0.0044 15.8 8.8 0.0052 15.5 8.8 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light HAUS-augmin3 PF14932.6 RJW62686.1 - 0.017 14.7 11.6 0.023 14.3 11.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ArAE_2_N PF10337.9 RJW62686.1 - 0.018 14.1 3.5 0.022 13.8 3.5 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal THOC7 PF05615.13 RJW62686.1 - 0.073 13.4 16.4 0.42 10.9 16.4 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 Cluap1 PF10234.9 RJW62686.1 - 0.091 12.1 13.9 0.35 10.2 13.5 1.7 1 1 1 2 2 2 0 Clusterin-associated protein-1 ZnuA PF01297.17 RJW62686.1 - 0.22 10.9 3.1 0.38 10.1 2.8 1.6 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic V_ATPase_I PF01496.19 RJW62686.1 - 0.6 8.0 6.4 0.75 7.6 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIVA PF05103.13 RJW62686.1 - 2.1 8.4 14.8 5.3 7.1 14.8 1.6 1 1 0 1 1 1 0 DivIVA protein bZIP_2 PF07716.15 RJW62686.1 - 5.8 7.1 14.1 3.3 7.8 11.4 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Couple_hipA PF13657.6 RJW62687.1 - 0.12 13.0 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 HipA N-terminal domain WH2 PF02205.20 RJW62689.1 - 0.0052 16.6 0.1 0.015 15.1 0.1 1.8 1 0 0 1 1 1 1 WH2 motif DUF1465 PF07323.12 RJW62689.1 - 0.05 13.4 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) COG5 PF10392.9 RJW62689.1 - 0.064 13.4 0.4 0.12 12.6 0.4 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 RhoGAP PF00620.27 RJW62690.1 - 1.9e-30 105.7 0.0 5.9e-30 104.1 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain Peptidase_C33 PF05412.12 RJW62692.1 - 0.036 14.1 0.0 1.8 8.6 0.0 2.8 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase DUF4417 PF14386.6 RJW62693.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) Elongin_A PF06881.11 RJW62694.1 - 0.0018 18.8 0.5 0.0018 18.8 0.5 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ig PF00047.25 RJW62695.1 - 9.7e-11 41.7 0.5 3e-05 24.1 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 RJW62695.1 - 2.6e-10 40.8 0.2 0.00017 22.1 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RJW62695.1 - 3.6e-09 36.8 0.2 1.9e-06 28.0 0.0 3.6 2 2 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 RJW62695.1 - 2.2e-06 27.6 0.0 6.3e-05 23.0 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_6 PF18452.1 RJW62695.1 - 8.9e-06 25.2 0.0 0.0072 15.9 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RJW62695.1 - 7.8e-05 22.9 0.0 0.01 16.2 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.15 RJW62695.1 - 0.011 16.1 0.0 0.047 14.1 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin C1-set domain COX4 PF02936.14 RJW62696.1 - 8.4e-26 90.6 0.0 1.4e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV BolA PF01722.18 RJW62696.1 - 1.2e-08 35.1 0.1 2e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 BolA-like protein RVT_1 PF00078.27 RJW62696.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3322 PF11795.8 RJW62696.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF4748 PF15932.5 RJW62696.1 - 1.1 9.0 3.1 2.1 8.2 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Inositol_P PF00459.25 RJW62698.1 - 2.9e-24 86.0 0.0 3.5e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Phage_sheath_1 PF04984.14 RJW62699.1 - 0.026 14.4 0.0 0.083 12.8 0.0 1.6 1 1 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain Methyltransf_16 PF10294.9 RJW62700.1 - 5.7e-13 49.0 0.0 9.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 RJW62700.1 - 0.00035 20.4 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW62700.1 - 0.0041 17.8 0.0 0.01 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RJW62700.1 - 0.032 13.8 0.0 0.085 12.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 RJW62700.1 - 0.039 13.8 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain 7tm_1 PF00001.21 RJW62701.1 - 2.2e-16 60.0 2.2 4.1e-16 59.1 1.7 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW62701.1 - 0.014 14.8 10.1 0.13 11.6 10.1 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.17 RJW62701.1 - 0.041 12.9 0.1 0.041 12.9 0.1 1.8 2 0 0 2 2 2 0 Frizzled/Smoothened family membrane region Ilar_coat PF01787.16 RJW62702.1 - 0.17 11.6 0.1 0.23 11.2 0.1 1.1 1 0 0 1 1 1 0 Ilarvirus coat protein Thioesterase PF00975.20 RJW62703.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain P4Ha_N PF08336.11 RJW62704.1 - 3.2e-25 88.7 0.1 9.2e-25 87.2 0.1 1.8 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 RJW62704.1 - 1.1e-13 51.8 0.2 3.3e-13 50.3 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 RJW62704.1 - 0.00092 19.2 3.6 0.013 15.6 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RJW62704.1 - 0.0066 16.5 0.1 0.0066 16.5 0.1 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat zf-nanos PF05741.13 RJW62704.1 - 0.019 15.2 0.1 0.31 11.3 0.0 2.4 2 0 0 2 2 2 0 Nanos RNA binding domain TPR_10 PF13374.6 RJW62704.1 - 0.42 10.5 2.3 0.59 10.1 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RJW62704.1 - 4.5 8.0 7.8 1.4 9.6 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_6 PF12774.7 RJW62706.1 - 3.2e-163 542.4 0.0 1.4e-162 540.2 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW62706.1 - 1.9e-134 448.8 9.0 2.8e-134 448.2 1.8 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RJW62706.1 - 2.4e-88 295.9 0.0 8.7e-88 294.0 0.0 2.1 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RJW62706.1 - 4.8e-81 270.6 0.4 7.1e-74 247.2 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 RJW62706.1 - 3.3e-26 91.9 0.2 7.2e-24 84.3 0.1 3.5 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RJW62706.1 - 4.7e-20 71.7 0.1 1.9e-19 69.7 0.1 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RJW62706.1 - 5e-20 71.9 0.0 7.5e-08 32.5 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 RJW62706.1 - 2.4e-09 37.7 0.8 0.079 13.4 0.0 5.7 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RJW62706.1 - 7.2e-08 33.1 0.1 0.074 13.6 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 RJW62706.1 - 7.8e-08 32.9 1.5 0.48 10.8 0.1 5.9 4 1 1 5 5 5 1 AAA ATPase domain AAA_22 PF13401.6 RJW62706.1 - 5.9e-07 29.8 0.1 0.95 9.7 0.0 5.7 6 0 0 6 6 4 2 AAA domain T2SSE PF00437.20 RJW62706.1 - 1e-05 24.7 0.0 0.5 9.4 0.0 4.0 4 0 0 4 4 4 2 Type II/IV secretion system protein Sigma54_activat PF00158.26 RJW62706.1 - 2.1e-05 24.3 0.2 0.09 12.5 0.0 4.1 4 0 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.22 RJW62706.1 - 5.5e-05 23.5 0.1 1.6 9.2 0.0 4.5 4 0 0 4 4 4 1 RNA helicase AAA_33 PF13671.6 RJW62706.1 - 0.00029 21.0 1.1 1.4 9.1 0.0 4.6 4 0 0 4 4 4 1 AAA domain TsaE PF02367.17 RJW62706.1 - 0.00058 19.9 3.1 0.41 10.7 0.1 3.8 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 RJW62706.1 - 0.0026 17.7 0.0 1.5 8.7 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 RJW62706.1 - 0.003 17.3 0.2 12 5.8 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_30 PF13604.6 RJW62706.1 - 0.0081 15.9 0.8 14 5.3 0.0 3.8 4 0 0 4 4 4 0 AAA domain DUF815 PF05673.13 RJW62706.1 - 0.011 14.9 0.1 6.4 5.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 RJW62706.1 - 0.024 15.2 0.2 1.8 9.1 0.1 3.6 3 0 0 3 3 2 0 ABC transporter Mg_chelatase PF01078.21 RJW62706.1 - 0.024 14.0 2.0 0.24 10.8 0.0 3.0 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 RJW62706.1 - 0.064 12.4 0.6 0.91 8.7 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain ResIII PF04851.15 RJW62706.1 - 0.068 13.2 0.4 4.4 7.3 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 RJW62706.1 - 0.13 12.1 2.0 5.9 6.8 0.0 3.5 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_23 PF13476.6 RJW62706.1 - 0.16 12.4 0.8 13 6.2 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 RJW62706.1 - 0.19 11.4 0.2 18 5.0 0.1 3.2 2 0 0 2 2 2 0 AAA domain RasGAP_C PF03836.15 RJW62706.1 - 0.19 11.8 3.5 0.093 12.9 0.2 2.2 2 0 0 2 2 1 0 RasGAP C-terminus AAA_19 PF13245.6 RJW62706.1 - 0.24 11.7 2.5 9.8 6.5 0.0 3.5 3 0 0 3 3 2 0 AAA domain BRE1 PF08647.11 RJW62706.1 - 3.9 7.6 6.2 4.3 7.5 0.4 3.6 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF1640 PF07798.11 RJW62706.1 - 5.7 7.0 8.1 0.24 11.4 0.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Nucleoporin_FG2 PF15967.5 RJW62709.1 - 0.068 11.7 0.4 0.077 11.5 0.4 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region KH_10 PF17905.1 RJW62710.1 - 6.9e-08 32.8 1.2 0.0013 19.2 0.6 3.5 2 1 0 2 2 2 2 GLD-3 KH domain 5 KH_1 PF00013.29 RJW62710.1 - 2e-07 30.7 0.1 0.004 17.0 0.0 3.9 4 1 0 4 4 4 2 KH domain SLS PF14611.6 RJW62710.1 - 0.0076 16.1 0.4 0.078 12.8 0.0 2.4 1 1 2 3 3 3 1 Mitochondrial inner-membrane-bound regulator DUF4974 PF16344.5 RJW62710.1 - 0.016 15.2 0.7 6.1 6.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4974) PWWP PF00855.17 RJW62711.1 - 6.3e-08 32.9 0.1 1.3e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 PWWP domain 7tm_1 PF00001.21 RJW62712.1 - 1.7e-10 40.6 13.3 4.3e-10 39.4 13.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW62712.1 - 0.0053 16.2 13.8 0.028 13.8 13.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF5316 PF17247.2 RJW62712.1 - 0.053 13.5 6.4 0.49 10.4 0.3 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5316) zf-U1 PF06220.12 RJW62713.1 - 2.1e-20 72.2 8.7 3.3e-20 71.6 8.7 1.3 1 0 0 1 1 1 1 U1 zinc finger DHO_dh PF01180.21 RJW62714.1 - 7.2e-87 291.3 0.0 8.7e-87 291.0 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 RJW62714.1 - 0.0026 16.9 0.1 0.013 14.5 0.1 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 RJW62714.1 - 0.0097 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Gln-synt_C PF00120.24 RJW62715.1 - 1e-76 258.2 0.0 1.3e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain AAA_6 PF12774.7 RJW62716.1 - 2.5e-150 500.0 0.1 4.5e-149 495.9 0.0 2.7 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW62716.1 - 2.7e-115 385.7 12.9 2.7e-115 385.7 12.9 1.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RJW62716.1 - 6.5e-85 284.6 0.0 1.4e-84 283.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RJW62716.1 - 2.6e-70 235.6 0.1 1e-63 214.2 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_1 PF17857.1 RJW62716.1 - 6.1e-23 80.9 0.1 6.4e-22 77.7 0.1 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 RJW62716.1 - 2.6e-22 79.3 0.0 6.9e-05 22.9 0.0 5.5 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RJW62716.1 - 1.6e-12 47.6 2.0 1.6e-10 41.2 0.2 3.6 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 RJW62716.1 - 9e-09 35.7 0.1 0.074 13.3 0.0 5.1 4 0 0 4 4 4 3 AAA domain AAA PF00004.29 RJW62716.1 - 1.2e-06 29.0 0.0 0.15 12.5 0.0 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW62716.1 - 3e-06 27.7 0.4 6.4 7.1 0.0 5.5 5 1 1 6 6 5 1 AAA ATPase domain AAA_19 PF13245.6 RJW62716.1 - 0.0015 18.9 0.3 26 5.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 RJW62716.1 - 0.004 17.7 0.0 0.19 12.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 RJW62716.1 - 0.0055 15.8 2.5 0.49 9.4 0.0 3.0 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_33 PF13671.6 RJW62716.1 - 0.012 15.8 0.4 7.9 6.6 0.0 3.4 4 0 0 4 4 2 0 AAA domain AAA_30 PF13604.6 RJW62716.1 - 0.033 13.9 0.7 4.9 6.8 1.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 RJW62716.1 - 0.37 11.2 2.7 37 4.8 0.0 3.7 5 0 0 5 5 4 0 RNA helicase STIL_N PF15253.6 RJW62718.1 - 5.4e-17 61.9 0.0 1.2e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus Thioredoxin PF00085.20 RJW62719.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin CH PF00307.31 RJW62720.1 - 7.7e-05 22.8 0.1 0.00014 22.0 0.1 1.5 1 1 0 1 1 1 1 Calponin homology (CH) domain RhoGEF PF00621.20 RJW62721.1 - 2.2e-28 99.8 3.3 5.8e-27 95.1 2.6 2.3 1 1 0 2 2 2 1 RhoGEF domain PH_10 PF15411.6 RJW62721.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Globin PF00042.22 RJW62722.1 - 4.3e-10 40.1 0.0 8.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Globin UME PF08064.13 RJW62722.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 UME (NUC010) domain TLD PF07534.16 RJW62723.1 - 5.7e-16 59.0 0.0 8.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 RJW62723.1 - 1.5e-07 31.3 0.0 0.00047 19.9 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain cobW PF02492.19 RJW62724.1 - 1.1e-48 165.1 0.0 1.8e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 RJW62724.1 - 7.2e-09 35.5 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 RJW62724.1 - 0.0014 18.6 0.3 0.53 10.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 RJW62724.1 - 0.052 13.6 0.6 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 RJW62724.1 - 0.072 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 RJW62724.1 - 0.1 11.6 0.7 0.81 8.6 0.1 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 RJW62724.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Fucokinase PF07959.12 RJW62725.1 - 1.3e-09 37.5 5.3 6.3e-08 32.0 1.9 2.5 1 1 2 3 3 3 2 L-fucokinase Hexapep PF00132.24 RJW62725.1 - 1.5e-06 27.7 5.9 0.011 15.4 2.1 3.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 RJW62725.1 - 0.00077 17.7 0.5 0.00095 17.4 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) DUF4292 PF14125.6 RJW62725.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) Hexapep_2 PF14602.6 RJW62725.1 - 0.11 12.3 8.6 1.5 8.7 5.0 3.1 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase 7tm_1 PF00001.21 RJW62727.1 - 1.1e-25 90.4 24.0 7.2e-18 64.8 8.6 3.1 2 1 0 3 3 3 3 7 transmembrane receptor (rhodopsin family) RRM_5 PF13893.6 RJW62730.1 - 4.7e-40 136.1 3.7 7.5e-31 106.3 0.0 4.9 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RJW62730.1 - 8.7e-24 83.1 0.0 1e-07 31.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RJW62730.1 - 2.8e-08 33.5 0.3 0.0018 18.1 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_8 PF11835.8 RJW62730.1 - 0.015 15.5 0.2 0.13 12.5 0.1 2.5 2 1 0 2 2 2 0 RRM-like domain ICEA PF05315.11 RJW62732.1 - 0.024 14.1 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 ICEA Protein Herpes_UL52 PF03121.15 RJW62733.1 - 4.4e-08 33.0 0.3 1.4e-07 31.3 0.2 1.9 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase Calponin PF00402.18 RJW62734.1 - 7.5e-10 38.3 1.3 1.7e-09 37.2 1.3 1.6 1 0 0 1 1 1 1 Calponin family repeat CH PF00307.31 RJW62734.1 - 7.6e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain RRM_1 PF00076.22 RJW62735.1 - 7.9e-35 118.5 0.2 1.9e-14 53.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW62735.1 - 7.2e-06 26.0 0.0 0.12 12.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 RJW62735.1 - 0.025 14.4 0.0 1.8 8.5 0.0 3.2 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_5 PF13893.6 RJW62735.1 - 0.098 12.3 0.0 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RJW62735.1 - 0.15 12.1 0.0 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 IF4E PF01652.18 RJW62740.1 - 4.4e-41 140.3 0.1 5.3e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E GIY-YIG PF01541.24 RJW62741.1 - 0.00048 20.4 0.1 0.00071 19.8 0.1 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain Nop PF01798.18 RJW62742.1 - 2.6e-30 105.6 1.5 6.8e-15 55.2 4.6 3.1 2 1 0 2 2 2 2 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 RJW62742.1 - 3.1e-10 40.3 0.4 6.5e-10 39.3 0.4 1.6 1 0 0 1 1 1 1 NOP5NT (NUC127) domain ATP-synt_DE PF00401.20 RJW62742.1 - 0.88 9.9 4.0 2.6 8.4 0.9 2.5 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Robl_LC7 PF03259.17 RJW62743.1 - 0.0014 18.4 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain Vps8 PF12816.7 RJW62744.1 - 2e-24 86.2 0.1 5.7e-23 81.5 0.1 2.4 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 zf-rbx1 PF12678.7 RJW62744.1 - 0.0028 17.9 6.3 0.0085 16.4 6.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Clathrin PF00637.20 RJW62744.1 - 0.0029 17.5 0.4 0.32 10.9 0.0 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_11 PF17123.5 RJW62744.1 - 0.02 14.6 1.0 0.052 13.3 0.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger PHD PF00628.29 RJW62744.1 - 0.021 14.7 2.3 0.069 13.1 2.3 1.9 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 RJW62744.1 - 0.031 14.6 7.1 0.14 12.5 7.1 2.3 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 RJW62744.1 - 0.05 13.5 5.6 0.18 11.7 5.6 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 ANAPC4_WD40 PF12894.7 RJW62744.1 - 0.072 13.4 0.1 3 8.2 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_UBOX PF13445.6 RJW62744.1 - 0.076 13.0 2.6 0.3 11.2 2.6 2.1 1 0 0 1 1 1 0 RING-type zinc-finger WD40 PF00400.32 RJW62744.1 - 0.45 11.5 2.9 0.47 11.4 0.1 2.7 2 0 0 2 2 1 0 WD domain, G-beta repeat zf-C3HC4 PF00097.25 RJW62744.1 - 1.5 8.7 5.4 6.1 6.8 5.4 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW62744.1 - 1.8 8.6 6.6 5.7 7.0 6.6 1.9 1 0 0 1 1 1 0 zinc-RING finger domain CUE PF02845.16 RJW62745.1 - 1.4e-06 27.9 0.0 3.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 CUE domain Inositol_P PF00459.25 RJW62746.1 - 1.2e-11 44.6 0.0 1.8e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Kp4 PF09044.10 RJW62746.1 - 0.0021 18.1 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Kp4 Plasmid_RAQPRD PF09686.10 RJW62746.1 - 0.063 13.5 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TES PF08034.11 RJW62748.1 - 6.5e-09 35.9 2.0 6.5e-09 35.9 2.0 7.0 5 2 0 6 6 6 1 Trematode eggshell synthesis protein 7tm_1 PF00001.21 RJW62750.1 - 0.00035 20.0 17.4 0.00066 19.1 17.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Yip1 PF04893.17 RJW62751.1 - 2.8e-05 23.9 4.8 0.022 14.5 0.0 2.7 2 1 0 2 2 2 2 Yip1 domain PDGF PF00341.17 RJW62751.1 - 0.13 12.6 6.2 3.5 8.0 0.5 2.4 2 0 0 2 2 2 0 PDGF/VEGF domain zf-NOSIP PF15906.5 RJW62751.1 - 0.61 10.3 3.6 21 5.4 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein DEAD PF00270.29 RJW62753.1 - 1.9e-44 151.5 0.0 5.6e-44 150.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW62753.1 - 5.2e-29 100.8 0.0 2e-28 98.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 RJW62753.1 - 0.0017 17.7 1.7 0.0041 16.5 0.0 2.2 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 RJW62753.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 RJW62753.1 - 0.12 12.5 2.7 0.21 11.7 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Cnd2 PF05786.14 RJW62753.1 - 3.5 6.2 7.9 7 5.2 7.9 1.3 1 1 0 1 1 1 0 Condensin complex subunit 2 RVT_1 PF00078.27 RJW62756.1 - 7.4e-39 133.5 0.0 1.4e-38 132.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sec34 PF04136.15 RJW62756.1 - 1.4e-17 63.9 0.0 4.2e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Sec34-like family SPG48 PF14764.6 RJW62756.1 - 0.021 15.3 0.0 0.077 13.5 0.0 1.9 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking Dynein_C PF18199.1 RJW62757.1 - 4.1e-81 272.6 0.0 6.9e-81 271.8 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RJW62757.1 - 4.2e-50 169.8 0.0 7.1e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RJW62757.1 - 4.1e-40 136.6 0.3 2e-39 134.3 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain E2 PF08199.11 RJW62760.1 - 0.12 12.3 0.3 0.26 11.2 0.3 1.5 1 0 0 1 1 1 0 Bacteriophage E2-like protein DLIC PF05783.11 RJW62761.1 - 5.6e-83 279.3 0.0 4.3e-71 240.2 0.0 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) 7tm_1 PF00001.21 RJW62766.1 - 0.00018 20.9 16.5 0.0003 20.2 16.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ELFV_dehydrog_N PF02812.18 RJW62767.1 - 5.1e-55 184.9 0.0 8.6e-55 184.1 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 RJW62767.1 - 8.3e-53 179.6 0.0 1.8e-50 171.9 0.0 2.2 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 RJW62767.1 - 0.021 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase_Tyr PF07714.17 RJW62769.1 - 0.00044 19.6 0.0 0.0022 17.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW62769.1 - 0.00075 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DNA_ligase_A_M PF01068.21 RJW62770.1 - 1.9e-58 197.5 0.1 3e-57 193.6 0.1 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 RJW62770.1 - 2.6e-32 112.5 0.1 5.6e-32 111.4 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 RJW62770.1 - 5.9e-25 87.8 0.0 1.8e-24 86.2 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 RJW62770.1 - 2.3e-05 24.8 0.0 3.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 RJW62770.1 - 0.021 14.8 0.3 9.8 6.3 0.0 2.9 2 0 0 2 2 2 0 DNA ligase OB-like domain GHL13 PF14883.6 RJW62770.1 - 0.033 13.3 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 TPR_8 PF13181.6 RJW62771.1 - 3.6e-13 48.6 0.9 0.13 12.6 0.1 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 RJW62771.1 - 1.3e-12 47.4 6.1 0.04 14.8 0.0 7.9 5 3 3 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 RJW62771.1 - 1e-10 41.2 3.6 0.094 13.1 0.0 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW62771.1 - 1.1e-10 41.9 3.4 0.099 13.2 0.0 7.0 5 2 4 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 RJW62771.1 - 1.7e-10 40.2 5.3 0.86 9.9 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 RJW62771.1 - 1.1e-09 37.7 2.2 1.6 8.7 0.2 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 RJW62771.1 - 2.5e-09 37.6 4.5 0.0034 18.0 0.0 6.2 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 RJW62771.1 - 7.6e-09 35.2 2.0 0.0018 17.5 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW62771.1 - 1.1e-07 31.4 7.7 0.44 10.7 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW62771.1 - 4.4e-07 30.1 10.7 0.056 13.7 0.0 6.4 5 2 1 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW62771.1 - 1.5e-06 28.3 0.1 1.4 9.2 0.0 4.5 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RJW62771.1 - 1.1e-05 25.7 5.2 38 5.2 0.1 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 RJW62771.1 - 2.2e-05 24.7 0.3 3.9 8.4 0.4 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW62771.1 - 0.016 15.3 0.1 1.3 9.2 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 RJW62771.1 - 0.036 14.4 2.6 9.4 6.7 0.1 4.4 4 2 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RJW62771.1 - 0.073 13.0 13.1 9.9 6.2 0.1 6.2 6 1 1 7 7 6 0 Tetratricopeptide repeat Roughex PF06020.11 RJW62771.1 - 2 7.4 7.7 0.13 11.3 2.6 1.5 2 0 0 2 2 2 0 Drosophila roughex protein UbiA PF01040.18 RJW62772.1 - 1.1e-12 47.8 4.2 2.4e-12 46.7 4.2 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family RhoGAP-FF1 PF16512.5 RJW62773.1 - 9.1e-07 29.5 0.0 2.8e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 p190-A and -B Rho GAPs FF domain Ras PF00071.22 RJW62773.1 - 0.0026 17.4 0.0 0.035 13.7 0.0 2.3 2 0 0 2 2 2 1 Ras family FeoB_N PF02421.18 RJW62773.1 - 0.036 13.6 0.0 0.61 9.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 RJW62773.1 - 0.071 12.6 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_C78 PF07910.13 RJW62774.1 - 1.6e-42 145.4 0.0 2.6e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 7TM_GPCR_Srw PF10324.9 RJW62775.1 - 6.1e-07 29.0 6.8 0.00034 20.0 0.9 2.5 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw Amino_oxidase PF01593.24 RJW62776.1 - 3.8e-25 89.1 0.0 6.2e-25 88.4 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RJW62776.1 - 2.3e-10 40.6 0.0 5.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RJW62776.1 - 3.1e-08 33.6 0.0 9.5e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase ApbA PF02558.16 RJW62776.1 - 0.0056 16.3 0.0 0.61 9.7 0.0 2.3 1 1 1 2 2 2 2 Ketopantoate reductase PanE/ApbA MCRA PF06100.11 RJW62776.1 - 0.0088 14.9 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 MCRA family NAD_binding_9 PF13454.6 RJW62776.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 RJW62776.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family E1_dh PF00676.20 RJW62778.1 - 6.7e-109 363.4 0.0 8.1e-109 363.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RJW62778.1 - 0.00041 19.6 0.0 0.00077 18.7 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 RJW62778.1 - 0.00081 19.2 0.8 0.0016 18.2 0.6 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4061 PF13270.6 RJW62780.1 - 8.5e-13 48.4 0.2 1.2e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) DUF2760 PF10816.8 RJW62780.1 - 0.01 15.7 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) FH2 PF02181.23 RJW62781.1 - 2.2e-74 250.8 8.3 3.1e-74 250.3 0.1 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 RJW62781.1 - 2.4e-22 79.5 9.0 5.9e-22 78.2 9.0 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 RJW62781.1 - 1.5e-21 76.8 1.2 5.7e-12 45.6 0.2 2.8 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Mito_fiss_reg PF05308.11 RJW62781.1 - 0.004 17.3 4.2 0.011 15.8 4.2 1.7 1 0 0 1 1 1 1 Mitochondrial fission regulator TolA_bind_tri PF16331.5 RJW62781.1 - 0.0044 17.1 6.2 0.0044 17.1 6.2 3.1 1 1 1 2 2 2 1 TolA binding protein trimerisation CLZ PF16526.5 RJW62781.1 - 0.082 13.3 0.3 0.082 13.3 0.3 5.3 3 1 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HalX PF08663.10 RJW62781.1 - 0.26 11.6 13.5 0.26 11.6 2.9 3.0 1 1 1 2 2 2 0 HalX domain DUF4559 PF15112.6 RJW62781.1 - 0.27 10.9 8.8 0.26 10.9 6.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Sipho_Gp157 PF05565.11 RJW62781.1 - 0.72 9.8 5.6 1.7 8.6 5.6 1.6 1 0 0 1 1 1 0 Siphovirus Gp157 Baculo_PEP_C PF04513.12 RJW62781.1 - 0.84 9.7 5.9 2.6 8.1 3.1 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.11 RJW62781.1 - 1.2 8.0 12.8 2.6 6.8 12.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fez1 PF06818.15 RJW62781.1 - 1.3 9.4 14.1 0.18 12.3 8.9 2.1 2 0 0 2 2 2 0 Fez1 DUF4472 PF14739.6 RJW62781.1 - 1.9 9.3 13.2 1.2 9.9 10.0 2.4 2 1 0 2 2 1 0 Domain of unknown function (DUF4472) ABC_tran_CTD PF16326.5 RJW62781.1 - 2.1 8.6 14.3 1.5 9.1 6.7 3.0 1 1 0 2 2 2 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 RJW62781.1 - 2.7 8.2 15.3 12 6.1 15.3 2.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Tnp_22_trimer PF17489.2 RJW62781.1 - 4.2 7.4 5.5 21 5.2 0.0 3.2 3 0 0 3 3 2 0 L1 transposable element trimerization domain Phage_GPO PF05929.11 RJW62781.1 - 5.3 6.6 14.9 6.5 6.3 7.9 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FUSC PF04632.12 RJW62781.1 - 5.5 5.4 12.7 1.1 7.8 7.3 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family TMPIT PF07851.13 RJW62781.1 - 5.7 6.1 5.6 17 4.5 5.6 1.8 1 0 0 1 1 1 0 TMPIT-like protein Golgin_A5 PF09787.9 RJW62781.1 - 6.3 6.2 19.2 1.3 8.4 14.7 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 Cpn60_TCP1 PF00118.24 RJW62782.1 - 7.3e-17 61.2 0.2 1.6e-16 60.0 0.2 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRM_1 PF00076.22 RJW62783.1 - 1.2e-14 53.9 0.0 1.8e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 RJW62783.1 - 6.5e-08 32.2 2.9 1.6e-07 30.9 2.9 1.7 1 0 0 1 1 1 1 SAP domain Uso1_p115_head PF04869.14 RJW62784.1 - 8.9e-39 133.4 0.0 9.8e-23 80.7 0.0 2.4 2 0 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 RJW62784.1 - 9.1e-26 89.6 2.5 3e-25 87.9 2.5 2.0 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor Metallophos PF00149.28 RJW62784.1 - 4e-09 37.3 0.8 7.8e-09 36.3 0.1 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Uso1_p115_C PF04871.13 RJW62784.1 - 9.5e-06 26.0 7.4 2.5e-05 24.7 7.4 1.6 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3636 PF12331.8 RJW62784.1 - 0.019 14.8 0.1 1.9 8.3 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) Fib_alpha PF08702.10 RJW62784.1 - 0.13 12.5 0.4 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 RJW62784.1 - 1.8 8.5 4.7 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CCDC53 PF10152.9 RJW62784.1 - 5.5 7.4 6.7 47 4.4 6.7 2.2 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Innexin PF00876.18 RJW62785.1 - 4.1e-122 407.9 0.0 5.5e-122 407.4 0.0 1.2 1 0 0 1 1 1 1 Innexin Romo1 PF10247.9 RJW62786.1 - 2.6e-25 88.5 17.1 3.2e-25 88.3 17.1 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 RJW62786.1 - 0.067 13.6 7.3 0.081 13.3 7.3 1.1 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Lar_restr_allev PF14354.6 RJW62787.1 - 0.21 12.0 6.9 2.7 8.4 5.4 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar IBR PF01485.21 RJW62787.1 - 0.28 11.5 11.1 0.16 12.3 9.3 1.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Rav1p_C PF12234.8 RJW62788.1 - 3.9e-54 184.2 0.0 8.8e-46 156.6 0.0 4.7 5 0 0 5 5 5 3 RAVE protein 1 C terminal WD40 PF00400.32 RJW62788.1 - 0.055 14.4 8.0 1e+02 4.0 0.1 6.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Auxin_inducible PF02519.14 RJW62788.1 - 0.18 12.0 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Auxin responsive protein Choline_kinase PF01633.20 RJW62790.1 - 8.4e-30 103.9 0.0 4.5e-22 78.7 0.1 2.0 1 1 1 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 RJW62790.1 - 2.5e-07 30.9 0.1 3.8e-07 30.3 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 RJW62790.1 - 0.005 16.2 0.0 0.006 15.9 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase RRM_1 PF00076.22 RJW62792.1 - 4.6e-12 45.6 0.0 9.4e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4164 PF13747.6 RJW62794.1 - 0.066 13.5 0.7 7.5 6.9 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) Peptidase_A17 PF05380.13 RJW62795.1 - 2.5e-07 30.9 0.0 3.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 RJW62796.1 - 0.0075 16.4 0.8 0.012 15.7 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain Tetraspanin PF00335.20 RJW62797.1 - 0.0019 17.9 4.5 0.0021 17.8 4.5 1.0 1 0 0 1 1 1 1 Tetraspanin family Corona_S2 PF01601.16 RJW62797.1 - 0.015 13.8 0.9 0.016 13.7 0.9 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein wnt PF00110.19 RJW62798.1 - 2.1e-103 346.1 24.7 2.4e-103 345.9 24.7 1.0 1 0 0 1 1 1 1 wnt family HAD_2 PF13419.6 RJW62799.1 - 4.8e-21 75.6 0.0 5.8e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RJW62799.1 - 2.5e-08 34.5 0.0 2e-05 25.0 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RJW62799.1 - 0.0024 17.9 0.0 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 RJW62799.1 - 0.073 13.2 0.0 5.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Tetraspanin PF00335.20 RJW62800.1 - 2.1e-36 125.8 6.2 3e-36 125.3 6.2 1.2 1 0 0 1 1 1 1 Tetraspanin family 2OG-FeII_Oxy_2 PF13532.6 RJW62803.1 - 1.1e-26 94.2 0.0 1.4e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IATP PF04568.12 RJW62804.1 - 2.6e-21 75.9 0.8 4e-21 75.3 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF5320 PF17253.2 RJW62804.1 - 0.011 16.8 0.2 0.017 16.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Peptidase_C1_2 PF03051.15 RJW62804.1 - 0.062 12.1 0.2 0.086 11.6 0.2 1.1 1 0 0 1 1 1 0 Peptidase C1-like family OATP PF03137.20 RJW62806.1 - 4.6e-77 259.6 0.0 3.3e-76 256.7 0.0 2.2 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.15 RJW62806.1 - 0.021 14.9 2.6 0.83 9.8 0.3 2.7 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Spin-Ssty PF02513.17 RJW62806.1 - 0.029 14.1 0.0 0.1 12.3 0.1 1.9 2 0 0 2 2 2 0 Spin/Ssty Family PDEase_I PF00233.19 RJW62807.1 - 2.1e-84 283.0 7.9 3.6e-84 282.2 7.9 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 RJW62807.1 - 3.3e-25 87.7 0.1 7.4e-25 86.6 0.1 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal PhoLip_ATPase_N PF16209.5 RJW62808.1 - 5.1e-34 115.8 2.9 5.9e-16 57.9 0.2 2.7 2 0 0 2 2 2 2 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 RJW62808.1 - 6.4e-15 55.1 0.0 6.8e-06 25.7 0.0 3.6 3 2 0 3 3 3 2 E1-E2 ATPase Orf78 PF06024.12 RJW62808.1 - 0.015 15.6 0.7 5.5 7.4 0.0 3.0 2 0 0 2 2 2 0 Orf78 (ac78) DUF1385 PF07136.11 RJW62808.1 - 0.027 13.8 8.8 0.52 9.6 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) TubC_N PF18563.1 RJW62808.1 - 0.029 14.4 0.1 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 TubC N-terminal docking domain DUF1281 PF06924.11 RJW62808.1 - 0.086 12.4 0.0 16 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) AbrB PF05145.12 RJW62808.1 - 0.23 10.4 4.0 0.074 12.0 0.3 2.0 2 0 0 2 2 2 0 Transition state regulatory protein AbrB PMP1_2 PF08114.11 RJW62808.1 - 4.7 7.0 7.5 2.3 8.0 0.2 3.2 3 0 0 3 3 3 0 ATPase proteolipid family RVT_1 PF00078.27 RJW62809.1 - 8.5e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 RJW62811.1 - 1.1e-61 208.6 0.0 2.1e-61 207.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW62811.1 - 2.2e-30 105.8 0.0 4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW62811.1 - 3.8e-07 29.7 0.0 8.2e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW62811.1 - 0.00019 20.5 0.0 0.00056 19.0 0.0 1.8 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RJW62811.1 - 0.00088 19.3 0.0 0.00088 19.3 0.0 3.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family C1_1 PF00130.22 RJW62811.1 - 0.0011 18.7 6.4 0.0011 18.7 6.4 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Abi_HHR PF07815.14 RJW62811.1 - 0.065 13.4 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Abl-interactor HHR Baculo_PEP_C PF04513.12 RJW62811.1 - 2.5 8.1 5.8 0.55 10.3 1.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_4 PF12799.7 RJW62813.1 - 1.4e-17 63.5 27.5 1.4e-07 31.7 6.0 6.3 3 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW62813.1 - 3.5e-14 52.7 12.3 2.1e-10 40.4 2.3 3.8 1 1 1 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 RJW62813.1 - 7.4e-14 51.3 32.1 0.00099 18.8 0.9 5.7 4 1 1 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 RJW62813.1 - 5.3e-05 22.9 11.8 11 6.3 0.1 6.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 RJW62813.1 - 0.019 15.4 18.5 9.1 7.3 0.1 7.3 8 0 0 8 8 8 0 Leucine Rich Repeat Flagellin_C PF00700.21 RJW62815.1 - 3.5 8.1 10.8 57 4.2 0.2 4.5 4 0 0 4 4 4 0 Bacterial flagellin C-terminal helical region Cation_efflux PF01545.21 RJW62817.1 - 1.1e-27 97.0 7.2 1.1e-27 97.0 7.2 1.4 2 0 0 2 2 2 1 Cation efflux family TspO_MBR PF03073.15 RJW62818.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 TspO/MBR family AMMECR1 PF01871.17 RJW62819.1 - 1e-46 158.6 0.0 1.3e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 FERM_N PF09379.10 RJW62821.1 - 1.2e-11 44.3 0.1 2.7e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 RJW62821.1 - 1.6e-11 44.4 0.5 3.6e-11 43.3 0.5 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RJW62821.1 - 9.8e-11 42.1 0.3 6.6e-10 39.4 0.0 2.6 2 0 0 2 2 2 1 FERM central domain Coilin_N PF15862.5 RJW62821.1 - 0.00038 20.3 0.0 0.067 13.0 0.0 3.4 3 1 0 3 3 3 1 Coilin N-terminus COesterase PF00135.28 RJW62824.1 - 3e-30 105.6 0.0 5.6e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RJW62824.1 - 4.2e-07 30.1 0.0 1.5e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Transglut_core3 PF13471.6 RJW62824.1 - 0.0015 18.5 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF2182 PF09948.9 RJW62824.1 - 0.05 13.5 1.1 0.086 12.7 0.1 1.8 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) DASH_Duo1 PF08651.10 RJW62825.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF4011 PF13195.6 RJW62825.1 - 0.044 13.7 5.0 0.067 13.1 4.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) Alpha_L_fucos PF01120.17 RJW62825.1 - 1.2 8.5 7.2 1.5 8.2 7.2 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase WD40 PF00400.32 RJW62826.1 - 7.4e-52 172.2 16.9 5e-10 39.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW62826.1 - 1.1e-19 70.5 0.1 0.00049 20.4 0.0 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW62826.1 - 3e-12 46.0 1.2 0.0057 15.3 0.0 4.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 RJW62826.1 - 7.1e-10 39.1 0.0 8e-05 22.6 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 RJW62826.1 - 6.5e-06 25.7 0.0 0.068 12.5 0.0 3.1 1 1 2 3 3 3 2 WD40-like domain PALB2_WD40 PF16756.5 RJW62826.1 - 0.0011 17.9 1.1 4.1 6.2 0.0 4.0 1 1 4 5 5 5 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 RJW62826.1 - 0.0019 16.6 0.0 0.13 10.5 0.0 2.2 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 RJW62826.1 - 0.0022 17.0 3.6 7.7 5.4 0.0 3.9 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 RJW62826.1 - 0.014 14.4 0.0 1.1 8.3 0.0 2.8 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain Hira PF07569.11 RJW62826.1 - 0.031 14.0 1.4 5.7 6.6 0.1 3.5 4 1 0 4 4 4 0 TUP1-like enhancer of split Herpes_UL52 PF03121.15 RJW62826.1 - 0.067 13.1 0.0 19 5.3 0.0 2.7 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase HMG_box PF00505.19 RJW62827.1 - 4.5e-25 87.9 1.4 9.4e-25 86.8 1.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW62827.1 - 7.1e-09 36.1 1.4 1.3e-08 35.2 1.4 1.5 1 0 0 1 1 1 1 HMG-box domain EF-hand_7 PF13499.6 RJW62828.1 - 5.1e-08 33.2 3.1 7.1e-08 32.8 2.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW62828.1 - 3e-07 29.9 2.6 0.00087 19.0 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RJW62828.1 - 0.00022 21.0 1.2 0.00064 19.5 1.2 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW62828.1 - 0.00034 20.0 0.3 0.00034 20.0 0.3 3.1 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 RJW62828.1 - 0.022 14.2 0.1 0.06 12.9 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_13 PF17958.1 RJW62828.1 - 0.038 13.8 0.1 0.3 10.9 0.1 2.3 1 1 0 1 1 1 0 EF-hand domain PDZ PF00595.24 RJW62830.1 - 8.4e-06 26.1 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW62830.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Aa_trans PF01490.18 RJW62833.1 - 1.9e-10 40.1 21.0 4e-05 22.5 15.6 2.7 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein DUF5489 PF17592.2 RJW62833.1 - 0.37 11.4 3.5 0.3 11.6 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5489) tRNA_m1G_MT PF01746.21 RJW62834.1 - 3.4e-17 62.8 0.0 6.2e-17 61.9 0.0 1.4 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase ABC_membrane PF00664.23 RJW62836.1 - 9.4e-53 179.6 27.2 1.2e-29 103.8 4.0 3.0 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RJW62836.1 - 1.9e-45 154.8 0.0 1e-22 81.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RJW62836.1 - 2.1e-09 37.2 0.9 0.079 12.4 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RJW62836.1 - 9e-07 29.0 0.0 0.59 9.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RJW62836.1 - 0.00011 22.5 0.5 9.3 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 RJW62836.1 - 0.0002 21.4 0.3 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 RJW62836.1 - 0.00021 21.7 2.4 0.098 13.0 0.2 3.2 3 1 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 RJW62836.1 - 0.00023 20.8 0.1 0.51 10.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 RJW62836.1 - 0.00083 19.5 0.4 0.023 14.8 0.1 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain Adeno_IVa2 PF02456.15 RJW62836.1 - 0.0009 18.1 0.0 0.42 9.3 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein RsgA_GTPase PF03193.16 RJW62836.1 - 0.0018 18.2 0.8 0.84 9.5 0.0 2.6 3 0 0 3 3 2 1 RsgA GTPase T2SSE PF00437.20 RJW62836.1 - 0.0025 16.9 0.0 0.62 9.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 RJW62836.1 - 0.0041 16.9 0.2 4.5 7.0 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_23 PF13476.6 RJW62836.1 - 0.0053 17.3 0.0 2.6 8.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 RJW62836.1 - 0.009 15.6 0.3 0.92 9.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 RJW62836.1 - 0.011 15.8 0.6 1.9 8.5 0.2 2.6 3 0 0 3 3 2 0 Dynamin family AAA_30 PF13604.6 RJW62836.1 - 0.013 15.2 0.5 2.5 7.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 RJW62836.1 - 0.029 13.9 0.1 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 RJW62836.1 - 0.046 14.2 0.2 9.5 6.7 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 RJW62836.1 - 0.071 13.4 0.1 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MTABC_N PF16185.5 RJW62836.1 - 0.12 11.8 12.0 0.39 10.2 12.0 1.9 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region NACHT PF05729.12 RJW62836.1 - 0.13 12.2 1.8 4.5 7.2 0.0 3.0 4 0 0 4 4 3 0 NACHT domain MeaB PF03308.16 RJW62836.1 - 0.14 11.1 0.1 17 4.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 RJW62836.1 - 0.23 10.8 1.1 0.52 9.6 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 RJW62836.1 - 0.25 10.5 0.1 13 4.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain WD40 PF00400.32 RJW62837.1 - 3e-10 40.5 5.9 0.00065 20.5 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Cyclin_N PF00134.23 RJW62838.1 - 2.3e-09 37.1 0.3 5.3e-09 35.9 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain GLE1 PF07817.13 RJW62838.1 - 0.042 13.0 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 GLE1-like protein Vps5 PF09325.10 RJW62839.1 - 9.1e-57 192.3 11.2 1.4e-56 191.7 11.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 RJW62839.1 - 2.8e-22 78.8 0.4 1.2e-21 76.8 0.0 2.3 3 0 0 3 3 3 1 PX domain Arfaptin PF06456.13 RJW62839.1 - 0.0071 15.9 6.5 0.42 10.2 6.5 2.5 1 1 0 1 1 1 1 Arfaptin-like domain DUF4471 PF14740.6 RJW62839.1 - 0.038 13.2 0.6 0.074 12.3 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) BAR_3_WASP_bdg PF10456.9 RJW62839.1 - 0.094 12.2 2.3 3.1 7.2 2.3 2.2 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein zf-C2H2_4 PF13894.6 RJW62842.1 - 5e-09 36.2 24.8 0.0046 17.7 0.4 5.3 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW62842.1 - 2.9e-07 30.6 14.0 0.0036 17.6 1.1 4.0 4 0 0 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 RJW62842.1 - 2e-06 27.9 32.7 0.00021 21.6 0.4 6.0 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 RJW62842.1 - 0.00078 20.1 4.6 0.28 11.9 0.8 3.4 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 RJW62842.1 - 0.0019 18.4 1.5 0.0019 18.4 1.5 3.6 3 0 0 3 3 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 RJW62842.1 - 0.028 14.3 3.4 0.12 12.2 0.2 3.3 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) DUF2256 PF10013.9 RJW62842.1 - 0.038 14.1 8.5 0.32 11.1 0.2 4.2 3 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 RJW62842.1 - 0.041 13.9 0.3 1.4 9.0 0.2 3.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-MIZ PF02891.20 RJW62842.1 - 0.045 13.5 0.1 0.045 13.5 0.1 3.6 4 0 0 4 4 4 0 MIZ/SP-RING zinc finger zf-met PF12874.7 RJW62842.1 - 0.075 13.4 15.6 1.3 9.5 0.8 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_12 PF18658.1 RJW62842.1 - 0.16 11.5 8.1 0.071 12.7 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger C2H2-type zf-C2H2_11 PF16622.5 RJW62842.1 - 0.2 11.5 19.9 0.24 11.2 0.4 4.4 5 0 0 5 5 5 0 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 RJW62842.1 - 0.26 11.8 5.9 36 5.0 0.1 4.2 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain Lar_restr_allev PF14354.6 RJW62842.1 - 0.29 11.6 13.4 0.15 12.5 2.3 3.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 RJW62842.1 - 0.6 9.7 7.6 2.7 7.6 0.0 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding UPF0547 PF10571.9 RJW62842.1 - 0.8 9.8 6.5 8.6 6.6 0.6 3.3 3 0 0 3 3 2 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 RJW62842.1 - 1.5 8.3 6.4 13 5.3 0.1 3.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 RJW62842.1 - 2.4 8.3 11.2 1 9.4 0.1 4.5 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 RJW62842.1 - 3.1 8.2 16.6 5.2 7.5 10.8 3.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) PQ-loop PF04193.14 RJW62843.1 - 4.3e-08 32.8 1.2 4.3e-08 32.8 1.2 2.7 2 1 1 3 3 3 1 PQ loop repeat COX7B PF05392.11 RJW62843.1 - 0.092 12.4 0.3 5 6.9 0.2 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB DCAF15_WD40 PF14939.6 RJW62846.1 - 4.7e-07 29.7 0.2 1.2e-06 28.4 0.2 1.6 1 1 0 1 1 1 1 DDB1-and CUL4-substrate receptor 15, WD repeat Glypican PF01153.19 RJW62847.1 - 5.9e-37 127.7 0.2 4e-35 121.7 0.4 2.1 2 0 0 2 2 2 2 Glypican GRDP-like PF07173.12 RJW62851.1 - 0.086 13.5 5.3 0.048 14.3 2.6 2.0 1 1 1 2 2 2 0 Glycine-rich domain-containing protein-like HlyD_2 PF12700.7 RJW62851.1 - 2.1 7.0 6.2 0.79 8.4 3.1 1.7 1 1 0 1 1 1 0 HlyD family secretion protein DUF3417 PF11897.8 RJW62851.1 - 5.5 7.5 9.4 0.33 11.4 1.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) OST3_OST6 PF04756.13 RJW62852.1 - 0.14 11.5 0.1 0.14 11.5 0.1 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family WD40 PF00400.32 RJW62853.1 - 1.2e-05 26.0 1.1 0.53 11.3 0.3 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW62853.1 - 0.0012 19.1 0.0 0.0072 16.6 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Arf PF00025.21 RJW62854.1 - 1.1e-33 116.2 0.1 2.6e-33 114.9 0.1 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 RJW62854.1 - 2.5e-06 27.0 0.0 3.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RJW62854.1 - 0.034 13.5 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Pkinase PF00069.25 RJW62856.1 - 4.2e-74 249.2 0.0 5.6e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW62856.1 - 3.6e-46 157.5 0.0 5.3e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 RJW62856.1 - 9.9e-13 48.3 0.0 3.9e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 RJW62856.1 - 9.9e-07 27.9 0.0 1.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW62856.1 - 1.3e-06 27.9 0.0 4.7e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 RJW62856.1 - 0.016 15.2 0.1 0.32 10.9 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.12 RJW62856.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain Haspin_kinase PF12330.8 RJW62856.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4140 PF13600.6 RJW62858.1 - 0.017 15.5 4.3 1 9.8 0.3 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 RJW62858.1 - 0.02 15.6 2.0 0.56 10.9 0.1 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Val_tRNA-synt_C PF10458.9 RJW62858.1 - 0.095 13.0 9.5 1.5 9.2 0.8 3.3 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm T4SS PF07996.11 RJW62858.1 - 0.28 11.6 13.2 1.5 9.1 2.6 3.2 3 0 0 3 3 3 0 Type IV secretion system proteins ABC_tran_CTD PF16326.5 RJW62858.1 - 0.37 11.1 4.1 0.73 10.1 0.2 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Snf7 PF03357.21 RJW62858.1 - 0.62 9.6 5.0 5.5 6.5 0.6 2.3 2 0 0 2 2 2 0 Snf7 DUF724 PF05266.14 RJW62858.1 - 1.9 8.3 7.1 1.7 8.5 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.8 RJW62858.1 - 2 8.5 5.5 3.5 7.7 0.7 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 RJW62858.1 - 3.8 7.2 9.6 2.1 8.1 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) DivIC PF04977.15 RJW62858.1 - 4 7.3 6.6 5.9 6.7 0.7 2.5 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 RJW62858.1 - 7.9 7.0 9.1 6.2 7.3 1.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Rad9 PF04139.13 RJW62860.1 - 5.5e-12 45.7 0.2 5.1e-11 42.5 0.2 1.9 1 1 0 1 1 1 1 Rad9 Josephin PF02099.17 RJW62862.1 - 1e-39 136.3 0.8 1.5e-39 135.7 0.1 1.6 2 0 0 2 2 2 1 Josephin UIM PF02809.20 RJW62862.1 - 0.0017 18.1 16.9 0.58 10.2 0.5 4.0 3 0 0 3 3 3 3 Ubiquitin interaction motif DUF1939 PF09154.10 RJW62862.1 - 0.19 11.9 0.2 0.55 10.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) Spc7 PF08317.11 RJW62865.1 - 1.5e-07 30.6 81.0 0.00026 20.0 28.7 5.6 2 1 3 5 5 5 4 Spc7 kinetochore protein BRE1 PF08647.11 RJW62865.1 - 0.00018 21.5 6.8 0.00018 21.5 6.8 7.4 4 1 3 7 7 6 2 BRE1 E3 ubiquitin ligase MIS13 PF08202.11 RJW62865.1 - 0.00062 19.1 14.9 0.00062 19.1 14.9 5.8 1 1 4 5 5 5 1 Mis12-Mtw1 protein family Allexi_40kDa PF05549.11 RJW62865.1 - 0.0032 17.0 5.4 0.0032 17.0 5.4 5.6 1 1 5 6 6 6 1 Allexivirus 40kDa protein DUF4407 PF14362.6 RJW62865.1 - 0.015 14.6 67.6 0.0089 15.4 15.1 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 RJW62865.1 - 0.021 14.9 53.1 0.59 10.2 2.4 7.5 3 3 4 7 7 7 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 RJW62865.1 - 0.028 14.4 0.8 0.028 14.4 0.8 9.3 6 1 2 9 9 8 0 Prefoldin subunit CLZ PF16526.5 RJW62865.1 - 0.038 14.4 0.6 0.038 14.4 0.6 9.2 3 1 6 10 10 9 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MtrG PF04210.13 RJW62865.1 - 0.048 13.5 3.7 1.2 9.0 0.0 4.0 4 0 0 4 4 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Fungal_TACC PF12709.7 RJW62865.1 - 0.22 12.0 0.1 0.22 12.0 0.1 8.7 5 2 4 10 10 9 0 Fungal Transforming acidic coiled-coil (TACC) proteins ATG16 PF08614.11 RJW62865.1 - 0.26 11.5 98.8 0.025 14.8 18.6 5.3 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) SHE3 PF17078.5 RJW62865.1 - 0.79 9.4 73.9 2.6 7.7 5.5 5.1 1 1 3 4 4 4 0 SWI5-dependent HO expression protein 3 TPR_MLP1_2 PF07926.12 RJW62865.1 - 0.96 9.5 98.1 0.031 14.3 4.6 7.7 3 1 3 7 7 7 0 TPR/MLP1/MLP2-like protein TACC_C PF05010.14 RJW62865.1 - 1.3 8.8 67.2 0.3 10.9 19.0 5.2 2 1 1 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal KASH_CCD PF14662.6 RJW62865.1 - 1.7 8.5 89.9 0.26 11.1 4.1 5.6 3 2 1 5 5 5 0 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 RJW62865.1 - 1.9 7.0 56.6 0.062 12.0 14.0 3.4 1 1 2 3 3 3 0 AAA domain DUF948 PF06103.11 RJW62865.1 - 2.1 8.7 30.4 0.22 11.8 0.5 6.6 5 1 1 7 7 7 0 Bacterial protein of unknown function (DUF948) MscS_porin PF12795.7 RJW62865.1 - 2.2 7.8 96.3 0.57 9.7 10.6 5.1 2 1 2 4 4 4 0 Mechanosensitive ion channel porin domain DUF1192 PF06698.11 RJW62865.1 - 3.5 7.8 24.1 9.1 6.4 0.4 7.7 7 1 1 8 8 8 0 Protein of unknown function (DUF1192) Alanine_zipper PF11839.8 RJW62865.1 - 3.9 7.9 23.6 6.2 7.3 0.8 6.8 5 2 2 7 7 6 0 Alanine-zipper, major outer membrane lipoprotein APG6_N PF17675.1 RJW62865.1 - 4.8 7.7 103.7 0.71 10.4 16.6 6.8 1 1 6 7 7 7 0 Apg6 coiled-coil region CALCOCO1 PF07888.11 RJW62865.1 - 5 5.9 94.0 11 4.7 49.6 3.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like EzrA PF06160.12 RJW62865.1 - 6.7 4.8 66.0 0.71 8.0 16.5 4.4 1 1 3 4 4 4 0 Septation ring formation regulator, EzrA APG17 PF04108.12 RJW62865.1 - 7.3 5.6 58.9 1.2 8.2 26.0 5.2 1 1 2 3 3 3 0 Autophagy protein Apg17 V-ATPase_G PF03179.15 RJW62866.1 - 1.5e-18 67.3 9.9 2.3e-18 66.7 9.9 1.3 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 RJW62866.1 - 0.29 11.5 8.4 0.48 10.8 8.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Aminotran_1_2 PF00155.21 RJW62867.1 - 1e-70 238.8 0.0 1.2e-70 238.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RJW62867.1 - 5.5e-05 22.3 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RJW62867.1 - 6.6e-05 22.4 0.5 0.00011 21.7 0.5 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 RJW62867.1 - 0.056 12.0 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Atg8 PF02991.16 RJW62867.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like DUF2587 PF10759.9 RJW62868.1 - 0.057 12.9 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PP2C PF00481.21 RJW62871.1 - 1.5e-76 257.4 0.0 1.8e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RJW62871.1 - 2.7e-05 23.9 0.0 4.6e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 RJW62871.1 - 0.019 15.4 0.1 0.039 14.4 0.1 1.6 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain PAP1 PF08601.10 RJW62871.1 - 0.38 10.4 1.0 0.59 9.8 1.0 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 fn3 PF00041.21 RJW62872.1 - 3.3e-17 62.6 0.0 4.8e-10 39.6 0.1 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW62872.1 - 0.0067 17.0 0.0 4.2 8.0 0.0 2.4 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain WAP PF00095.21 RJW62872.1 - 0.011 16.2 12.3 0.011 16.2 12.3 2.6 2 1 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Radial_spoke PF04712.12 RJW62873.1 - 6.2e-12 45.2 0.0 9.9e-06 24.8 0.0 3.0 2 1 0 3 3 3 3 Radial spokehead-like protein DUF3506 PF12014.8 RJW62873.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) UCH PF00443.29 RJW62875.1 - 6.5e-20 71.7 0.0 2e-19 70.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW62875.1 - 7e-05 22.6 0.2 7e-05 22.6 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase XRCC4 PF06632.12 RJW62875.1 - 0.16 10.8 0.2 0.28 10.0 0.2 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 HTH_3 PF01381.22 RJW62876.1 - 3.3e-14 52.7 1.2 5.3e-14 52.0 1.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 RJW62876.1 - 3.6e-11 43.4 0.6 7.3e-11 42.4 0.6 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 RJW62876.1 - 2.2e-05 24.7 0.0 3.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 RJW62876.1 - 3.6e-05 23.7 0.7 6.1e-05 23.0 0.7 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 RJW62876.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_38 PF13936.6 RJW62876.1 - 0.14 11.9 0.2 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_25 PF13413.6 RJW62876.1 - 0.14 12.0 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain FAD_binding_1 PF00667.20 RJW62877.1 - 1.1e-19 71.0 0.0 2.1e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 RJW62877.1 - 9.6e-11 42.3 0.0 3.2e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RJW62877.1 - 0.0071 16.5 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain RNA_pol_Rpb2_6 PF00562.28 RJW62879.1 - 1.6e-94 317.2 0.0 1.6e-93 313.8 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 RJW62879.1 - 4e-27 95.0 0.0 1.3e-26 93.4 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 RJW62879.1 - 3.2e-23 81.7 0.0 9.7e-23 80.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 RJW62879.1 - 4.1e-18 65.1 0.0 8.5e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 RJW62879.1 - 1e-13 51.5 0.4 7.2e-10 39.1 0.2 2.8 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 RJW62879.1 - 7.4e-07 29.0 0.0 6.4e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 PHD PF00628.29 RJW62879.1 - 1.7 8.6 4.7 1.4 8.9 1.1 2.7 2 1 0 2 2 2 0 PHD-finger RasGAP PF00616.19 RJW62880.1 - 6.5e-18 65.2 0.0 2.1e-17 63.5 0.0 1.8 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 RJW62880.1 - 3.2e-06 27.4 0.0 1.6e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 C2 domain WD40 PF00400.32 RJW62881.1 - 5.7e-35 118.8 3.9 3.8e-06 27.5 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW62881.1 - 1.6e-18 66.8 0.0 0.00025 21.3 0.0 5.2 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW62881.1 - 1.1e-09 38.5 0.0 4.8e-08 33.1 0.0 3.1 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A CSTF1_dimer PF16699.5 RJW62881.1 - 2.2e-07 30.5 0.1 4.3e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Ge1_WD40 PF16529.5 RJW62881.1 - 1.6e-06 27.4 1.7 0.00016 20.7 0.1 3.2 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 RJW62881.1 - 0.00025 19.5 0.1 0.0051 15.2 0.1 1.7 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 RJW62881.1 - 0.014 14.7 0.0 2.6 7.3 0.0 3.2 4 0 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 RJW62881.1 - 0.046 12.2 0.0 0.081 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain NDUF_B12 PF08122.12 RJW62882.1 - 1.8e-16 59.9 0.5 2.6e-16 59.4 0.5 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Cadherin PF00028.17 RJW62883.1 - 1e-56 189.3 0.4 1.3e-13 51.2 0.0 8.3 6 2 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 RJW62883.1 - 1.2e-08 34.7 0.0 0.00088 19.1 0.0 5.6 6 0 0 6 6 6 2 Cadherin-like GBP PF02263.19 RJW62884.1 - 1.6e-85 286.5 0.0 2.4e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain DUF2304 PF10066.9 RJW62884.1 - 0.065 13.5 1.1 0.16 12.2 1.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) AAA_33 PF13671.6 RJW62887.1 - 7.7e-24 84.5 0.0 1.5e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain SAP PF02037.27 RJW62887.1 - 1.6e-11 43.7 0.1 3.2e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 SAP domain AAA_18 PF13238.6 RJW62887.1 - 1e-05 26.1 0.1 2.4e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RJW62887.1 - 0.0078 15.5 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 RJW62887.1 - 0.024 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain EF-hand_1 PF00036.32 RJW62888.1 - 1.3e-17 61.9 2.6 9.4e-09 34.2 0.2 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW62888.1 - 8.8e-16 58.1 0.7 1e-15 57.9 0.7 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RJW62888.1 - 5.2e-14 51.0 1.4 6.7e-08 31.7 0.2 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW62888.1 - 1.9e-13 49.1 2.6 2.8e-09 36.1 0.8 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RJW62888.1 - 9.2e-13 47.8 5.6 1.1e-10 41.2 1.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW62888.1 - 0.00059 20.1 0.0 0.0008 19.7 0.0 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 RJW62888.1 - 0.0069 17.2 0.0 0.0074 17.1 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 RJW62888.1 - 0.0084 16.0 0.0 0.0095 15.9 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RJW62888.1 - 0.05 13.8 0.6 0.16 12.2 0.5 1.8 1 1 1 2 2 2 0 Dockerin type I domain EF-hand_9 PF14658.6 RJW62888.1 - 0.14 12.5 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 RJW62891.1 - 8.1e-40 136.8 0.0 1.5e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW62891.1 - 9.7e-21 74.2 0.0 1.6e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 RJW62891.1 - 3.6e-12 46.0 10.3 8.1e-12 44.8 10.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.14 RJW62891.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FYVE_2 PF02318.16 RJW62891.1 - 0.033 14.4 2.5 0.1 12.8 2.5 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger PHD PF00628.29 RJW62891.1 - 0.045 13.7 8.1 0.15 11.9 8.1 1.9 1 1 0 1 1 1 0 PHD-finger C1_2 PF03107.16 RJW62891.1 - 0.046 14.0 4.8 0.1 12.9 4.8 1.6 1 0 0 1 1 1 0 C1 domain PHD_2 PF13831.6 RJW62891.1 - 7.1 6.3 8.8 0.085 12.4 0.8 2.0 2 0 0 2 2 2 0 PHD-finger Nucleoside_tran PF01733.18 RJW62892.1 - 9.6e-54 182.8 2.6 1.1e-53 182.6 2.6 1.0 1 0 0 1 1 1 1 Nucleoside transporter Ilm1 PF10311.9 RJW62892.1 - 0.059 13.0 0.0 0.073 12.7 0.0 1.5 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 Coronavirus_5 PF05528.11 RJW62893.1 - 0.061 13.3 0.1 0.091 12.8 0.1 1.3 1 1 0 1 1 1 0 Coronavirus gene 5 protein McyA_C PF12593.8 RJW62893.1 - 0.092 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Microcystin synthetase C terminal ALG3 PF05208.13 RJW62895.1 - 0.11 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 ALG3 protein Ras PF00071.22 RJW62898.1 - 2.8e-10 40.0 0.1 0.00015 21.4 0.2 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RJW62898.1 - 1.5e-08 34.9 0.0 1.4e-06 28.5 0.1 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW62898.1 - 0.00014 21.4 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 RJW62898.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RJW62898.1 - 0.045 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ENTH PF01417.20 RJW62899.1 - 2.1e-29 102.1 0.2 3.9e-29 101.2 0.2 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 RJW62899.1 - 0.0011 18.1 0.2 0.0023 17.0 0.2 1.5 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 RJW62899.1 - 6.9 6.8 7.2 0.85 9.7 1.9 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif PrmA PF06325.13 RJW62900.1 - 2.3e-07 30.5 0.1 3.4e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 RJW62900.1 - 7.1e-06 26.7 0.0 1.4e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 RJW62900.1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 RJW62900.1 - 0.00024 20.8 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 RJW62900.1 - 0.00031 20.3 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 RJW62900.1 - 0.0025 18.5 0.0 0.005 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 RJW62900.1 - 0.0056 16.4 0.0 0.0085 15.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 RJW62900.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 RJW62900.1 - 0.015 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 RJW62900.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 RJW62900.1 - 0.062 13.3 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 RJW62900.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 RJW62900.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 RJW62900.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RRM_1 PF00076.22 RJW62903.1 - 4.6e-16 58.4 0.1 7.8e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW62903.1 - 0.00046 20.2 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 RJW62903.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.29 RJW62903.1 - 0.029 14.2 3.9 0.095 12.6 3.9 1.9 1 0 0 1 1 1 0 PHD-finger Peptidase_M16_C PF05193.21 RJW62905.1 - 6.4e-37 127.3 0.0 4.3e-34 118.1 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RJW62905.1 - 4.2e-25 88.5 0.0 1.2e-24 86.9 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Transcrip_reg PF01709.20 RJW62906.1 - 4.9e-42 144.0 0.0 5.6e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator AbbA_antirepres PF14156.6 RJW62906.1 - 0.069 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Antirepressor AbbA C1_1 PF00130.22 RJW62907.1 - 0.086 12.7 1.4 0.19 11.6 1.4 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) KH_1 PF00013.29 RJW62910.1 - 4e-107 350.1 11.3 4.3e-15 55.3 0.1 15.5 16 0 0 16 16 16 11 KH domain SLS PF14611.6 RJW62910.1 - 1.9e-09 37.7 16.1 0.011 15.6 0.0 8.7 4 2 6 11 11 11 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 RJW62910.1 - 0.00017 21.4 3.6 1.8 8.5 0.0 6.2 6 1 1 7 7 7 1 KH domain BMC PF00936.19 RJW62910.1 - 0.0016 18.4 1.8 24 5.0 0.0 6.0 8 0 0 8 8 8 0 BMC domain MOEP19 PF16005.5 RJW62910.1 - 0.0067 16.4 0.1 13 5.9 0.0 5.1 4 2 2 6 6 6 1 KH-like RNA-binding domain DUF2017 PF09438.10 RJW62910.1 - 0.087 12.7 0.2 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2017) TrkA_C PF02080.21 RJW62910.1 - 0.14 12.0 0.5 45 4.0 0.1 5.1 5 0 0 5 5 5 0 TrkA-C domain Secretin_N PF03958.17 RJW62910.1 - 0.3 11.5 7.9 30 5.1 0.1 7.0 9 1 0 9 9 9 0 Bacterial type II/III secretion system short domain DUF3090 PF11290.8 RJW62910.1 - 1.1 9.0 4.1 23 4.7 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3090) FtsQ PF03799.15 RJW62910.1 - 2.5 8.9 5.9 60 4.5 0.2 5.2 5 1 1 6 6 6 0 Cell division protein FtsQ WD40 PF00400.32 RJW62911.1 - 8.4e-05 23.3 1.2 0.36 11.8 0.2 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-UBR PF02207.20 RJW62912.1 - 9.1e-19 67.4 13.4 2e-18 66.3 13.4 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 RJW62912.1 - 3.3e-18 65.3 0.1 9.2e-18 63.8 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CaKB PF03185.15 RJW62913.1 - 5.2e-11 42.6 1.8 0.0044 16.7 0.0 3.1 3 0 0 3 3 3 3 Calcium-activated potassium channel, beta subunit Cofilin_ADF PF00241.20 RJW62918.1 - 0.074 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein FOP_dimer PF09398.10 RJW62919.1 - 1.7e-08 34.6 0.1 8.2e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 RJW62919.1 - 1.1e-05 24.4 0.3 1.7e-05 23.8 0.3 1.3 1 0 0 1 1 1 1 LisH DUF423 PF04241.15 RJW62922.1 - 9.8e-23 80.2 0.3 2.2e-22 79.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Acyltransferase PF01553.21 RJW62924.1 - 1.3e-21 76.6 0.0 8.9e-21 73.9 0.0 2.0 1 1 1 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 RJW62924.1 - 5.5e-08 32.8 0.2 1.2e-07 31.7 0.2 1.6 1 1 0 1 1 1 1 Acyltransferase C-terminus Arm PF00514.23 RJW62927.1 - 1.1e-86 282.5 13.3 1.5e-12 47.1 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 RJW62927.1 - 1.8e-23 81.8 0.0 3.1e-21 74.7 0.1 2.4 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 RJW62927.1 - 5.1e-23 81.1 3.9 1.7e-09 37.9 0.1 6.6 4 2 4 8 8 8 4 HEAT-like repeat IBB PF01749.20 RJW62927.1 - 1.1e-21 77.1 0.0 1.2e-19 70.5 0.0 2.4 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 RJW62927.1 - 1.5e-20 73.4 0.3 1.6e-07 31.6 0.0 5.6 3 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 RJW62927.1 - 1.1e-17 62.6 6.6 0.00013 21.9 0.0 7.3 8 0 0 8 8 7 4 HEAT repeat Adaptin_N PF01602.20 RJW62927.1 - 7e-08 31.5 0.0 2.8e-06 26.2 0.0 2.1 1 1 1 2 2 2 1 Adaptin N terminal region Arm_2 PF04826.13 RJW62927.1 - 8.9e-07 28.6 0.4 0.067 12.6 0.0 3.7 2 1 2 4 4 4 3 Armadillo-like Cnd1 PF12717.7 RJW62927.1 - 5.2e-06 26.6 0.0 3.1 7.8 0.0 3.9 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 RJW62927.1 - 0.0012 19.3 0.9 1.6e+02 3.4 0.0 6.4 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 RJW62927.1 - 0.0085 16.2 0.0 15 5.8 0.0 3.6 2 1 3 5 5 5 0 V-ATPase subunit H ParcG PF10274.9 RJW62927.1 - 0.0089 16.2 0.0 0.24 11.5 0.0 2.7 3 0 0 3 3 3 1 Parkin co-regulated protein RICTOR_V PF14668.6 RJW62927.1 - 0.056 13.7 4.8 14 6.0 0.1 4.4 3 3 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Snurportin1 PF11538.8 RJW62927.1 - 0.94 9.7 6.4 1.8 8.8 6.4 1.5 1 0 0 1 1 1 0 Snurportin1 DDE_Tnp_IS1595 PF12762.7 RJW62928.1 - 2.8e-09 37.2 0.0 4.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain RVT_1 PF00078.27 RJW62930.1 - 6.6e-09 35.6 0.0 9.8e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp PF00026.23 RJW62932.1 - 4.3e-28 98.6 0.0 6.2e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF2505 PF10698.9 RJW62933.1 - 0.096 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) TDP43_N PF18694.1 RJW62934.1 - 2.1e-29 101.2 0.0 3.9e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 RJW62934.1 - 1.5e-23 82.4 0.0 8.5e-11 41.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW62934.1 - 5.6e-05 23.2 0.2 0.02 15.0 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RJW62934.1 - 6.4e-05 22.9 0.1 0.0046 16.9 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 RJW62934.1 - 0.02 14.8 0.0 0.84 9.6 0.0 2.3 2 0 0 2 2 2 0 RL domain Nup35_RRM PF05172.13 RJW62934.1 - 0.049 13.6 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 RJW62936.1 - 6.9e-39 133.8 0.1 1.1e-38 133.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW62936.1 - 5.8e-20 71.7 0.0 7.4e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 RJW62936.1 - 5.3e-08 32.6 6.4 1.2e-07 31.5 6.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PB1 PF00564.24 RJW62936.1 - 2.9e-07 30.3 0.0 5.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Haspin_kinase PF12330.8 RJW62936.1 - 0.0044 16.0 0.2 0.012 14.6 0.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 RJW62936.1 - 0.011 15.4 0.1 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RJW62936.1 - 0.078 12.9 0.0 0.19 11.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family RhoGAP PF00620.27 RJW62938.1 - 1.2e-29 103.1 0.1 1.9e-16 60.3 0.1 3.5 3 0 0 3 3 3 2 RhoGAP domain PurA PF04845.13 RJW62939.1 - 6.8e-08 32.1 0.0 9.9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein RVT_1 PF00078.27 RJW62940.1 - 1.1e-16 61.1 0.0 1.7e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos PF00149.28 RJW62942.1 - 2.8e-19 70.4 0.0 4.4e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RJW62942.1 - 0.073 13.5 0.4 0.14 12.6 0.4 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain MFS_1 PF07690.16 RJW62943.1 - 1.7e-20 73.3 38.4 1.6e-15 56.9 16.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Glyco_transf_22 PF03901.17 RJW62944.1 - 9.2e-43 147.0 24.6 1.4e-42 146.4 24.6 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SIR2 PF02146.17 RJW62944.1 - 4e-22 79.0 0.0 9e-16 58.3 0.0 2.5 1 1 1 2 2 2 2 Sir2 family zf-H2C2_5 PF13909.6 RJW62944.1 - 0.0049 16.6 1.1 0.013 15.2 1.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 RJW62944.1 - 5.1 6.8 9.3 0.62 9.7 0.1 3.2 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain VASt PF16016.5 RJW62945.1 - 1.1e-29 103.8 0.0 3.1e-29 102.4 0.0 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 RJW62945.1 - 5.2e-29 100.4 1.5 4.4e-18 65.2 0.4 2.4 2 0 0 2 2 2 2 GRAM domain Peptidase_C36 PF05415.11 RJW62945.1 - 0.039 14.2 0.0 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase MFS_1 PF07690.16 RJW62946.1 - 3.3e-13 49.3 23.5 5.9e-13 48.5 23.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 RJW62947.1 - 5.1e-16 58.5 34.3 3.5e-11 42.6 14.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RJW62947.1 - 0.004 16.1 2.8 0.004 16.1 2.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Integrase_H2C2 PF17921.1 RJW62951.1 - 0.022 14.8 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain RVP PF00077.20 RJW62951.1 - 0.086 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease MFS_1 PF07690.16 RJW62953.1 - 1.8e-15 56.7 20.5 1.8e-15 56.7 20.5 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily PPTA PF01239.22 RJW62955.1 - 1.5e-43 145.3 20.0 1.9e-11 43.3 0.2 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat PAP2 PF01569.21 RJW62959.1 - 1.3e-24 86.5 1.1 2.7e-24 85.5 1.1 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 RJW62959.1 - 0.00022 20.9 4.1 0.0007 19.3 4.1 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 RJW62959.1 - 0.012 16.1 1.9 0.012 16.1 1.9 2.4 2 1 0 2 2 2 0 PAP2 superfamily C-terminal DUF202 PF02656.15 RJW62959.1 - 0.22 12.0 2.0 0.5 10.9 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) LRR_4 PF12799.7 RJW62961.1 - 2.6e-09 37.2 12.5 6e-05 23.3 2.4 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.23 RJW62961.1 - 8.6e-08 32.0 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 RJW62961.1 - 1.8e-05 24.4 4.6 1.8e-05 24.4 4.6 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 RJW62961.1 - 0.36 11.5 6.8 2.8 8.8 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat rRNA_proc-arch PF13234.6 RJW62962.1 - 1.5e-70 238.3 0.0 2.6e-70 237.5 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 RJW62962.1 - 9.9e-49 165.2 0.6 9.9e-49 165.2 0.6 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 RJW62962.1 - 7.5e-19 68.2 0.0 6.6e-18 65.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW62962.1 - 8e-06 26.2 0.0 8.6e-05 22.9 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RJW62962.1 - 0.012 15.9 0.0 0.1 12.9 0.0 2.6 2 1 1 3 3 3 0 AAA domain EF-hand_14 PF17959.1 RJW62962.1 - 0.041 14.2 0.1 0.18 12.2 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain Ecm29 PF13001.7 RJW62963.1 - 6.1e-20 71.4 0.0 3.6e-18 65.5 0.0 3.0 2 1 0 2 2 2 1 Proteasome stabiliser HEAT_2 PF13646.6 RJW62963.1 - 0.0037 17.6 19.0 0.22 11.9 0.0 6.5 7 1 3 10 10 10 5 HEAT repeats Arm PF00514.23 RJW62963.1 - 0.0076 16.3 0.4 0.56 10.3 0.0 4.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RJW62963.1 - 0.1 12.9 22.3 0.11 12.8 0.0 7.4 7 0 0 7 7 7 0 HEAT repeat Spt20 PF12090.8 RJW62963.1 - 1.5 8.4 5.7 2.9 7.4 5.7 1.4 1 0 0 1 1 1 0 Spt20 family DUF3509 PF12021.8 RJW62964.1 - 0.0039 16.9 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) Phe_tRNA-synt_N PF02912.18 RJW62965.1 - 0.73 9.8 7.0 3.1 7.8 1.0 3.2 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain PAP2 PF01569.21 RJW62966.1 - 6e-25 87.6 1.8 7.2e-25 87.3 1.1 1.5 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 RJW62966.1 - 4.9e-05 23.8 9.0 0.00015 22.2 2.6 2.5 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 RJW62966.1 - 0.00013 21.7 3.1 0.00043 20.0 3.1 1.9 1 1 0 1 1 1 1 PAP2 superfamily DUF475 PF04332.15 RJW62966.1 - 0.023 14.5 0.6 6.9 6.4 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF475) Syndecan PF01034.20 RJW62966.1 - 0.13 12.2 0.1 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Syndecan domain FUSC_2 PF13515.6 RJW62966.1 - 1.4 9.0 8.4 14 5.8 2.6 2.8 2 2 1 3 3 3 0 Fusaric acid resistance protein-like Hormone_recep PF00104.30 RJW62968.1 - 8.4e-05 22.2 0.3 0.00019 21.1 0.3 1.5 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ADK_lid PF05191.14 RJW62968.1 - 0.028 14.4 0.8 0.075 13.0 0.8 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-C4 PF00105.18 RJW62968.1 - 0.17 12.4 11.1 0.37 11.3 11.1 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Prok-RING_1 PF14446.6 RJW62968.1 - 0.23 11.4 4.9 0.58 10.1 4.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2318 PF10080.9 RJW62968.1 - 0.61 10.2 5.5 1.1 9.4 5.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) PHD PF00628.29 RJW62968.1 - 7 6.6 11.2 16 5.5 11.2 1.6 1 0 0 1 1 1 0 PHD-finger GCP_N_terminal PF17681.1 RJW62969.1 - 9.6e-63 212.6 0.0 1.4e-62 212.1 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 RJW62969.1 - 2.4e-39 135.7 0.5 9.8e-39 133.6 0.3 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal TFIIE_beta PF02186.15 RJW62971.1 - 1e-17 64.1 0.1 2.3e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain WW PF00397.26 RJW62971.1 - 5e-06 26.5 0.0 0.087 12.9 0.2 2.6 2 0 0 2 2 2 2 WW domain TFA2_Winged_2 PF18121.1 RJW62971.1 - 0.00016 21.3 0.0 0.00033 20.3 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 adh_short PF00106.25 RJW62971.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Coprogen_oxidas PF01218.18 RJW62971.1 - 0.16 10.6 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase LANC_like PF05147.13 RJW62974.1 - 3.2e-60 203.6 0.0 3.9e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 RJW62974.1 - 0.16 11.4 0.2 0.45 10.0 0.0 1.7 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus WD40 PF00400.32 RJW62976.1 - 2e-09 37.9 16.4 0.049 14.5 0.2 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW62976.1 - 6.1e-06 26.5 0.0 0.032 14.5 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CRT10 PF08728.10 RJW62976.1 - 0.14 10.3 0.0 6 4.9 0.0 2.1 2 0 0 2 2 2 0 CRT10 ZapC PF07126.12 RJW62977.1 - 0.1 12.1 0.2 0.13 11.8 0.2 1.1 1 0 0 1 1 1 0 Cell-division protein ZapC adh_short PF00106.25 RJW62978.1 - 7.8e-29 100.5 0.1 4.4e-17 62.2 0.0 2.9 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RJW62978.1 - 7.2e-17 61.7 0.0 8.2e-11 41.9 0.0 2.8 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RJW62978.1 - 6.5e-06 25.8 0.1 1.2e-05 24.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 RJW62978.1 - 0.00012 22.0 0.0 0.00046 20.1 0.0 1.9 2 1 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 RJW62978.1 - 0.00086 18.8 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 RJW62978.1 - 0.019 14.9 0.0 0.14 12.0 0.0 2.2 2 1 1 3 3 3 0 NAD(P)H-binding ApbA PF02558.16 RJW62978.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.26 RJW62978.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RVT_1 PF00078.27 RJW62979.1 - 3.4e-41 141.2 0.0 8.8e-41 139.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1298 PF06974.13 RJW62980.1 - 0.01 15.8 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1298) DUF1077 PF06417.12 RJW62981.1 - 4.5e-39 133.1 0.3 7.6e-39 132.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF1667 PF07892.11 RJW62982.1 - 0.093 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) GIY-YIG PF01541.24 RJW62982.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain 3HCDH_N PF02737.18 RJW62983.1 - 5.5e-49 166.5 0.0 9.2e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RJW62983.1 - 1e-05 25.8 0.0 3e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 RJW62983.1 - 1.3e-05 25.2 0.1 0.00011 22.2 0.1 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 RJW62983.1 - 0.0017 17.7 0.1 0.0047 16.2 0.1 1.6 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 RJW62983.1 - 0.034 13.7 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DFP PF04127.15 RJW62983.1 - 0.046 13.5 0.1 0.076 12.8 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Pyr_redox_2 PF07992.14 RJW62983.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NES_C_h PF18208.1 RJW62983.1 - 0.13 12.6 0.1 4 7.8 0.0 2.2 1 1 1 2 2 2 0 Nicking enzyme C-terminal middle helical domain F420_oxidored PF03807.17 RJW62983.1 - 0.16 12.6 0.7 0.71 10.5 0.7 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 RJW62983.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding MFS_1 PF07690.16 RJW62984.1 - 3.4e-15 55.8 46.6 1.5e-08 34.0 10.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_4 PF13637.6 RJW62985.1 - 1.7e-32 111.4 7.5 1.4e-14 54.2 0.6 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW62985.1 - 2.9e-30 104.7 0.3 8.5e-17 61.5 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW62985.1 - 2.2e-29 101.1 6.5 8e-12 45.2 0.7 4.2 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW62985.1 - 1.5e-26 89.5 1.8 1.5e-08 34.2 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 RJW62985.1 - 1.9e-24 84.9 4.5 1.8e-07 31.3 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Pro_isomerase PF00160.21 RJW62986.1 - 1.3e-49 168.5 0.3 5.4e-49 166.5 0.1 2.0 2 1 1 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 RJW62986.1 - 2.7e-08 33.5 0.0 5.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4944 PF16302.5 RJW62986.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) RRM_5 PF13893.6 RJW62986.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2594 PF10769.9 RJW62986.1 - 0.24 11.5 0.5 7.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) Pkinase_Tyr PF07714.17 RJW62987.1 - 1.2e-34 119.8 0.0 4e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW62987.1 - 2.6e-34 118.8 0.0 4.1e-23 82.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 RJW62987.1 - 0.0066 15.3 0.0 0.083 11.6 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase DUF3012 PF11216.8 RJW62987.1 - 0.041 13.9 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) MAGI_u5 PF16666.5 RJW62987.1 - 1.5 9.0 4.3 1.4 9.0 1.6 2.1 2 0 0 2 2 2 0 Unstructured region on MAGI Death PF00531.22 RJW62988.1 - 1.7e-05 24.9 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Death domain ZU5 PF00791.20 RJW62988.1 - 0.02 15.2 0.1 0.14 12.5 0.1 2.4 2 0 0 2 2 2 0 ZU5 domain DUF104 PF01954.16 RJW62988.1 - 0.07 13.6 0.3 0.18 12.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF104 MFS_1 PF07690.16 RJW62989.1 - 8.6e-20 71.0 14.7 3.7e-18 65.6 10.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RJW62989.1 - 5.2e-11 42.1 5.4 5.2e-11 42.1 5.4 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 RJW62989.1 - 0.0017 17.8 1.8 0.0028 17.0 1.8 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 RJW62989.1 - 0.0017 17.0 5.1 0.0017 17.0 5.1 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein Flavi_NS4A PF01350.17 RJW62989.1 - 0.071 13.1 0.7 0.15 12.0 0.5 1.6 1 1 0 1 1 1 0 Flavivirus non-structural protein NS4A LSM PF01423.22 RJW62991.1 - 3.9e-16 58.5 1.2 5.3e-16 58.1 1.2 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.8 RJW62991.1 - 0.063 13.2 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Hfq PF17209.3 RJW62991.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.4 1 1 0 1 1 1 0 Hfq protein Bestrophin PF01062.21 RJW62992.1 - 2.4e-82 276.6 2.8 3e-82 276.3 2.8 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Vut_1 PF02592.15 RJW62992.1 - 0.12 12.7 0.3 0.12 12.7 0.3 1.7 2 0 0 2 2 2 0 Putative vitamin uptake transporter MmcB-like PF06319.12 RJW62992.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA repair protein MmcB-like Galactosyl_T PF01762.21 RJW62993.1 - 2.5e-08 34.0 0.0 4.8e-06 26.5 0.0 2.2 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 RJW62993.1 - 5.8e-07 29.2 1.0 7.2e-06 25.6 1.0 2.0 1 1 0 1 1 1 1 Fringe-like DUF2826 PF11442.8 RJW62993.1 - 0.076 12.9 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) NUC173 PF08161.12 RJW62994.1 - 5.8e-16 58.8 7.3 4e-15 56.0 0.1 3.9 4 0 0 4 4 4 2 NUC173 domain TAN PF11640.8 RJW62994.1 - 0.34 11.0 5.2 0.33 11.1 0.2 3.7 3 1 1 4 4 4 0 Telomere-length maintenance and DNA damage repair EF-G-binding_N PF07299.11 RJW62994.1 - 0.91 10.1 3.8 17 6.0 0.1 3.8 4 0 0 4 4 4 0 Elongation factor G-binding protein, N-terminal Asp PF00026.23 RJW62995.1 - 3.7e-21 75.9 0.0 4.3e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW62995.1 - 0.00026 20.8 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Trypsin_2 PF13365.6 RJW62996.1 - 6e-25 88.9 0.5 1.5e-24 87.6 0.5 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RJW62996.1 - 7.2e-13 48.9 0.0 1.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 RJW62996.1 - 6.2e-10 39.3 0.0 1.2e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW62996.1 - 9.6e-10 38.2 0.1 2.3e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW62996.1 - 3.4e-07 30.5 0.0 7.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 RJW62996.1 - 0.0062 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain GRASP55_65 PF04495.14 RJW62996.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Peptidase_S46 PF10459.9 RJW62996.1 - 0.33 9.5 2.3 0.4 9.3 0.3 1.8 2 0 0 2 2 2 0 Peptidase S46 zf-C2H2_jaz PF12171.8 RJW62998.1 - 0.00017 21.8 0.1 0.00035 20.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW62998.1 - 0.00045 20.5 0.3 0.001 19.4 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RJW62998.1 - 0.0055 17.0 0.1 0.013 15.8 0.1 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) ACD PF16671.5 RJW62998.1 - 0.091 11.1 0.0 0.16 10.3 0.0 1.3 1 0 0 1 1 1 0 Actin cross-linking domain Polysacc_synt_4 PF04669.13 RJW62999.1 - 9.5e-20 71.0 0.1 1.5e-17 63.8 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis AMP-binding PF00501.28 RJW63000.1 - 2.1e-61 207.8 0.0 2.5e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RJW63000.1 - 0.01 16.8 0.0 0.036 15.0 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DSPc PF00782.20 RJW63001.1 - 6.7e-34 116.6 0.0 1.1e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 RJW63001.1 - 4.2e-10 39.4 0.4 8.2e-10 38.5 0.4 1.4 1 0 0 1 1 1 1 DEK C terminal domain PTPlike_phytase PF14566.6 RJW63001.1 - 9.3e-06 25.8 0.3 0.00067 19.8 0.1 2.4 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 RJW63001.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase OTU PF02338.19 RJW63001.1 - 0.14 12.7 0.4 0.44 11.0 0.2 1.9 1 1 1 2 2 2 0 OTU-like cysteine protease RVT_1 PF00078.27 RJW63003.1 - 2.8e-45 154.6 0.0 4.8e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW63003.1 - 0.00012 21.7 0.6 0.00025 20.6 0.6 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SDA1 PF05285.12 RJW63004.1 - 3.1e-05 23.6 38.0 3.6e-05 23.4 38.0 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RJW63004.1 - 3.6e-05 22.2 40.8 4e-05 22.1 40.8 1.0 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 RJW63004.1 - 0.00056 18.5 42.7 0.00064 18.3 42.7 1.1 1 0 0 1 1 1 1 Mpp10 protein RR_TM4-6 PF06459.12 RJW63004.1 - 0.0036 17.2 26.0 0.0043 16.9 26.0 1.3 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 RJW63004.1 - 0.0042 16.1 9.3 0.0046 16.0 9.3 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Caldesmon PF02029.15 RJW63004.1 - 0.0063 15.3 39.2 0.0071 15.2 39.2 1.1 1 0 0 1 1 1 1 Caldesmon Nop53 PF07767.11 RJW63004.1 - 0.0096 15.4 41.5 0.011 15.1 41.5 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) SAPS PF04499.15 RJW63004.1 - 0.011 14.6 12.9 0.011 14.6 12.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CCSAP PF15748.5 RJW63004.1 - 0.06 13.5 22.4 0.067 13.4 22.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PIP5K PF01504.18 RJW63004.1 - 0.08 12.2 5.9 0.093 11.9 5.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CDC45 PF02724.14 RJW63004.1 - 0.11 10.7 38.0 0.15 10.4 38.0 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 RJW63004.1 - 0.11 11.8 39.2 0.13 11.5 39.2 1.1 1 0 0 1 1 1 0 BUD22 RNA_polI_A34 PF08208.11 RJW63004.1 - 0.14 12.2 35.1 0.2 11.7 35.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.10 RJW63004.1 - 0.15 12.4 24.7 0.2 12.0 24.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4045 PF13254.6 RJW63004.1 - 0.18 11.4 20.4 0.19 11.4 20.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Tim54 PF11711.8 RJW63004.1 - 0.19 10.5 24.8 0.3 9.8 24.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 RJW63004.1 - 0.21 10.3 22.3 0.27 10.0 22.3 1.1 1 0 0 1 1 1 0 Presenilin Drc1-Sld2 PF11719.8 RJW63004.1 - 0.27 10.8 23.0 0.32 10.5 23.0 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein BORG_CEP PF14957.6 RJW63004.1 - 0.51 11.5 10.0 0.62 11.2 10.0 1.4 1 0 0 1 1 1 0 Cdc42 effector AAA_11 PF13086.6 RJW63004.1 - 0.55 10.0 12.4 0.67 9.7 12.4 1.2 1 0 0 1 1 1 0 AAA domain SID-1_RNA_chan PF13965.6 RJW63004.1 - 0.61 8.4 5.4 0.59 8.5 5.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NPR3 PF03666.13 RJW63004.1 - 0.86 8.3 19.0 1 8.1 19.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 RJW63004.1 - 1 8.7 50.3 1.5 8.1 50.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FGF-BP1 PF06473.12 RJW63004.1 - 1.4 8.7 18.5 2 8.2 18.5 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Endostatin PF06482.11 RJW63004.1 - 1.4 8.3 4.9 1.5 8.2 4.9 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF262 PF03235.14 RJW63004.1 - 1.7 8.7 10.2 1.9 8.6 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Plasmodium_Vir PF05795.11 RJW63004.1 - 2.3 7.6 15.6 2.7 7.3 15.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CSG2 PF16965.5 RJW63004.1 - 2.4 7.0 5.2 2.9 6.7 5.2 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF5308 PF17233.2 RJW63004.1 - 2.6 8.2 6.8 3.6 7.8 6.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Hid1 PF12722.7 RJW63004.1 - 3.5 5.6 20.2 3.5 5.6 20.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FRQ PF09421.10 RJW63004.1 - 4 5.3 16.4 3.9 5.4 16.4 1.0 1 0 0 1 1 1 0 Frequency clock protein CLN3 PF02487.17 RJW63004.1 - 4.1 6.3 12.1 5.2 6.0 12.1 1.1 1 0 0 1 1 1 0 CLN3 protein Smg8_Smg9 PF10220.9 RJW63004.1 - 4.2 5.6 14.9 4.3 5.5 14.9 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Gti1_Pac2 PF09729.9 RJW63004.1 - 4.9 7.2 12.5 6.2 6.9 12.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 RJW63004.1 - 6.2 5.7 16.7 7.6 5.4 16.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 RJW63004.1 - 6.3 6.8 11.0 6.6 6.7 11.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 RJW63004.1 - 6.4 5.6 15.3 6.9 5.5 15.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM60A PF15396.6 RJW63004.1 - 6.5 6.7 11.7 8.5 6.3 11.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.12 RJW63004.1 - 8.7 6.0 35.8 11 5.6 35.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MCM_bind PF09739.9 RJW63004.1 - 9.3 4.6 18.0 11 4.3 18.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Zip PF02535.22 RJW63004.1 - 9.3 5.4 16.8 11 5.1 16.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2828 PF11443.8 RJW63004.1 - 9.4 4.2 17.4 14 3.6 17.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Fn_bind PF02986.14 RJW63006.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Fibronectin binding repeat Fumble PF03630.14 RJW63007.1 - 6.4e-119 397.0 0.0 8.3e-119 396.6 0.0 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 RJW63007.1 - 2.1e-38 132.2 0.0 3.3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 dDENN PF03455.19 RJW63008.1 - 0.052 13.5 1.9 0.096 12.7 1.3 1.7 2 0 0 2 2 2 0 dDENN domain Pneumo_M2 PF07380.11 RJW63009.1 - 0.19 12.0 0.1 0.19 12.0 0.1 1.4 2 0 0 2 2 2 0 Pneumovirus M2 protein Phosphodiest PF01663.22 RJW63012.1 - 3.1e-41 142.2 0.0 2.3e-40 139.3 0.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RJW63012.1 - 1.8e-08 34.1 0.0 0.008 15.6 0.0 3.1 3 1 0 3 3 3 2 Sulfatase Metalloenzyme PF01676.18 RJW63012.1 - 3.7e-07 29.7 0.0 3.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Metalloenzyme superfamily PglZ PF08665.12 RJW63012.1 - 0.021 14.9 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 PglZ domain CbiK PF06180.11 RJW63012.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DUF687 PF05095.12 RJW63012.1 - 0.068 11.7 0.3 0.1 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF687) IBR PF01485.21 RJW63013.1 - 6.7e-26 90.3 26.0 3.1e-14 52.9 7.3 3.7 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain DUF667 PF05018.13 RJW63017.1 - 3.4e-83 277.9 0.1 5.1e-83 277.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF667) GTP_EFTU PF00009.27 RJW63018.1 - 8.8e-19 67.8 0.0 1.4e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RJW63018.1 - 0.02 14.9 0.1 0.1 12.7 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 RJW63018.1 - 0.17 12.3 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Scs3p PF10261.9 RJW63019.1 - 0.023 14.2 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM TFR_dimer PF04253.15 RJW63019.1 - 0.045 13.8 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain adh_short_C2 PF13561.6 RJW63020.1 - 6e-22 78.3 0.0 9.9e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RJW63020.1 - 3.5e-21 75.6 0.0 6.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase SCP2 PF02036.17 RJW63020.1 - 5e-14 52.6 0.0 1.1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 RJW63020.1 - 0.0053 17.0 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DUF4139 PF13598.6 RJW63022.1 - 4.3e-32 111.5 0.0 8.6e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 RJW63022.1 - 3.8e-20 72.1 4.6 2.9e-19 69.3 0.3 2.4 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Tropomyosin_1 PF12718.7 RJW63022.1 - 0.11 12.7 6.3 0.028 14.6 1.8 1.9 2 0 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.12 RJW63022.1 - 0.22 11.5 0.6 1.9 8.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 RJW63022.1 - 0.4 11.2 6.1 2.4 8.7 1.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 RJW63022.1 - 0.78 10.0 5.2 11 6.2 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PspA_IM30 PF04012.12 RJW63022.1 - 1.3 8.5 7.4 0.93 9.0 2.5 2.1 2 0 0 2 2 2 0 PspA/IM30 family HLH PF00010.26 RJW63023.1 - 2.9e-14 52.8 0.1 5.2e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ion_trans PF00520.31 RJW63024.1 - 7.8e-32 110.4 42.1 2.2e-16 59.8 9.7 2.2 2 0 0 2 2 2 2 Ion transport protein MINDY_DUB PF04424.13 RJW63024.1 - 0.029 14.4 0.4 0.16 12.0 0.1 2.4 2 0 0 2 2 2 0 MINDY deubiquitinase V-set PF07686.17 RJW63025.1 - 9.6e-15 54.7 7.7 1.3 9.2 0.0 10.1 10 0 0 10 10 10 6 Immunoglobulin V-set domain I-set PF07679.16 RJW63025.1 - 0.00027 21.0 1.8 17 5.6 0.0 7.0 7 0 0 7 7 7 1 Immunoglobulin I-set domain Ig_6 PF18452.1 RJW63025.1 - 0.0025 17.3 10.5 8.9 6.0 0.0 7.1 8 0 0 8 8 8 3 Immunoglobulin domain ig PF00047.25 RJW63025.1 - 0.023 14.9 13.1 15 5.8 0.1 8.6 8 0 0 8 8 8 0 Immunoglobulin domain Spec3 PF15795.5 RJW63026.1 - 0.21 12.2 0.2 0.21 12.2 0.2 1.7 2 0 0 2 2 2 0 Ectodermal ciliogenesis protein Paf1 PF03985.13 RJW63027.1 - 2.4e-146 488.0 8.0 2.4e-146 488.0 8.0 2.1 1 1 1 2 2 2 1 Paf1 Pkinase PF00069.25 RJW63029.1 - 5e-57 193.3 0.0 8.1e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 RJW63029.1 - 1.2e-35 121.8 0.0 3e-35 120.5 0.0 1.7 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 RJW63029.1 - 1e-26 93.8 0.0 2.6e-26 92.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase rve PF00665.26 RJW63029.1 - 1.9e-14 53.9 0.1 1.3e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Kinase-like PF14531.6 RJW63029.1 - 8.2e-05 22.1 0.1 0.00028 20.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like rve_3 PF13683.6 RJW63029.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 RJW63029.1 - 0.00032 20.9 0.1 0.00078 19.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase_fungal PF17667.1 RJW63029.1 - 0.00085 18.2 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RJW63029.1 - 0.0015 17.6 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RJW63029.1 - 0.17 11.8 1.2 1.5 8.7 0.0 2.7 2 1 0 3 3 3 0 Phosphotransferase enzyme family CymA PF16941.5 RJW63030.1 - 0.014 14.7 0.0 0.54 9.4 0.0 2.1 2 0 0 2 2 2 0 Putative cyclodextrin porin MyTH4 PF00784.17 RJW63031.1 - 2e-14 54.0 0.9 6.4e-08 33.1 0.0 3.2 4 0 0 4 4 4 2 MyTH4 domain PH PF00169.29 RJW63031.1 - 8.4e-10 39.1 0.1 0.0013 19.3 0.0 3.9 2 2 0 2 2 2 2 PH domain FERM_M PF00373.18 RJW63031.1 - 0.00059 20.2 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 FERM central domain P66_CC PF16563.5 RJW63036.1 - 1.2e-05 24.8 6.0 1.2e-05 24.8 6.0 3.7 3 0 0 3 3 3 1 Coiled-coil and interaction region of P66A and P66B with MBD2 GATA PF00320.27 RJW63036.1 - 8.5e-05 22.1 0.7 0.0002 20.9 0.7 1.6 1 0 0 1 1 1 1 GATA zinc finger 7tm_1 PF00001.21 RJW63039.1 - 2e-36 125.7 10.0 3.1e-36 125.1 10.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sema PF01403.19 RJW63040.1 - 6e-19 68.2 0.0 6.9e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Sema domain V-ATPase_C PF03223.15 RJW63041.1 - 4.5e-148 493.6 2.2 5.8e-148 493.2 2.2 1.1 1 0 0 1 1 1 1 V-ATPase subunit C 2-Hacid_dh_C PF02826.19 RJW63043.1 - 4.6e-55 185.7 0.0 6.6e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RJW63043.1 - 2.1e-26 92.2 0.0 3.2e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RJW63043.1 - 0.00015 21.9 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF58 PF01882.18 RJW63044.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF58 AMP-binding PF00501.28 RJW63045.1 - 7.1e-66 222.5 0.0 8.4e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ada3 PF10198.9 RJW63046.1 - 3.8e-12 46.5 2.2 2.6e-11 43.8 2.9 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Integrase_H2C2 PF17921.1 RJW63048.1 - 0.0018 18.3 0.5 0.0065 16.5 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Methyltransf_25 PF13649.6 RJW63049.1 - 2.1e-09 37.9 0.0 4.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RJW63049.1 - 2.5e-08 33.7 0.0 3.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 RJW63049.1 - 2e-06 27.7 0.1 4.6e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RJW63049.1 - 2.6e-06 28.0 0.0 6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 RJW63049.1 - 3.6e-06 26.1 0.1 8.7e-06 24.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 RJW63049.1 - 1.2e-05 25.2 0.0 4.7e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 RJW63049.1 - 3.1e-05 23.6 0.1 5.1e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 RJW63049.1 - 0.0017 18.3 0.1 0.0027 17.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RJW63049.1 - 0.0027 17.1 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 RJW63049.1 - 0.024 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 RJW63049.1 - 0.026 15.3 0.0 0.047 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 RJW63049.1 - 0.031 14.0 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 RJW63049.1 - 0.053 13.4 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 RJW63049.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RNase_T PF00929.24 RJW63050.1 - 4.8e-21 76.0 0.0 7.6e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Dev_Cell_Death PF10539.9 RJW63050.1 - 0.037 13.9 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Development and cell death domain Nkap_C PF06047.11 RJW63051.1 - 1.3e-47 160.1 0.9 1.3e-47 160.1 0.9 2.2 3 0 0 3 3 3 1 NF-kappa-B-activating protein C-terminal domain Med25_VWA PF11265.8 RJW63052.1 - 2.4e-06 27.5 0.0 8.6e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A DUF640 PF04852.12 RJW63053.1 - 0.059 13.5 0.0 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF640) E1_dh PF00676.20 RJW63055.1 - 3.7e-82 275.6 0.0 5.2e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 RJW63055.1 - 1.3e-51 174.8 0.0 1.7e-50 171.2 0.0 2.0 1 1 1 2 2 2 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 RJW63055.1 - 3.7e-50 169.6 0.0 6e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Peptidase_S80 PF07230.11 RJW63055.1 - 0.077 11.3 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) R2K_2 PF18299.1 RJW63055.1 - 0.097 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 MLD PF11647.8 RJW63057.1 - 0.13 12.6 0.8 0.99 9.7 0.1 2.4 1 1 1 2 2 2 0 Membrane Localization Domain Voltage_CLC PF00654.20 RJW63059.1 - 1.5e-86 290.8 32.5 1.5e-86 290.8 32.5 1.5 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 RJW63059.1 - 2.5e-13 50.2 0.1 1.8e-06 28.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF3382 PF11862.8 RJW63059.1 - 3.3 8.1 9.0 0.16 12.2 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) IF-2B PF01008.17 RJW63060.1 - 1.5e-53 181.8 0.0 1.8e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Vps35 PF03635.17 RJW63060.1 - 0.016 13.8 0.0 0.019 13.5 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Importin_rep_3 PF18806.1 RJW63060.1 - 0.13 12.3 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Importin 13 repeat 7tm_1 PF00001.21 RJW63061.1 - 1.3e-46 159.0 11.1 1.6e-46 158.7 11.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW63061.1 - 1.9e-06 27.7 17.0 3e-06 27.1 17.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RJW63061.1 - 1.1e-05 25.0 10.5 1.6e-05 24.4 10.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Orthopox_A36R PF05950.11 RJW63061.1 - 1.9 8.7 3.7 1.6 8.8 0.1 2.0 2 0 0 2 2 2 0 Orthopoxvirus A36R protein CTD_bind PF04818.13 RJW63062.1 - 0.0082 16.9 0.0 0.021 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf_UBZ PF18439.1 RJW63062.1 - 0.013 15.1 0.3 0.032 13.8 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 RJW63062.1 - 0.089 12.6 3.2 0.2 11.4 1.4 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Rsa3 PF14615.6 RJW63062.1 - 0.12 12.0 1.3 0.24 11.0 1.3 1.5 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Ribosomal_S26e PF01283.19 RJW63065.1 - 5.4e-22 78.3 1.6 6.4e-22 78.0 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Shikimate_DH PF01488.20 RJW63066.1 - 0.045 13.8 0.2 0.12 12.4 0.2 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 RJW63067.1 - 5e-27 94.9 17.2 1.3e-26 93.5 17.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW63067.1 - 3.6e-18 65.6 18.5 3.6e-18 65.6 18.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 RJW63068.1 - 2.4e-75 253.7 0.0 5.9e-74 249.2 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 RJW63068.1 - 0.048 14.7 0.0 0.15 13.0 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Bestrophin PF01062.21 RJW63069.1 - 1.9e-31 109.6 1.9 2.4e-31 109.2 1.9 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel CUB PF00431.20 RJW63070.1 - 6.2e-47 158.5 0.3 3.7e-23 82.0 0.1 2.3 2 0 0 2 2 2 2 CUB domain Noggin PF05806.12 RJW63071.1 - 5.3e-21 75.5 0.4 9.2e-21 74.7 0.4 1.3 1 0 0 1 1 1 1 Noggin Pkinase PF00069.25 RJW63073.1 - 5.8e-40 137.3 0.0 9.1e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63073.1 - 1.4e-14 54.0 0.0 5e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW63073.1 - 0.0021 17.1 0.0 0.0021 17.1 0.0 2.1 3 0 0 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 RJW63073.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RJW63073.1 - 0.039 13.9 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Lig_chan-Glu_bd PF10613.9 RJW63074.1 - 1e-19 70.8 0.0 1.8e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RJW63074.1 - 1.2e-10 41.3 0.0 4.4e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 RNase_T PF00929.24 RJW63076.1 - 6e-36 124.5 0.0 7.1e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 RJW63076.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like RVT_1 PF00078.27 RJW63077.1 - 6.3e-06 25.9 0.0 0.048 13.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.25 RJW63079.1 - 7.7e-42 143.0 0.0 1e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW63079.1 - 3.4e-21 75.9 0.0 4.3e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW63079.1 - 8.8e-08 32.3 0.1 4.3e-07 30.0 0.1 1.9 1 1 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 RJW63079.1 - 0.044 13.7 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.15 RJW63079.1 - 0.09 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 RJW63079.1 - 0.17 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MBOAT PF03062.19 RJW63080.1 - 9.3e-24 84.4 22.9 9.3e-24 84.4 22.9 1.7 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ras PF00071.22 RJW63081.1 - 3.8e-52 176.2 0.1 4.5e-52 175.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW63081.1 - 8.4e-21 74.4 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW63081.1 - 8.5e-10 38.4 0.0 1.1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW63081.1 - 3.1e-07 30.1 0.5 8e-07 28.8 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RJW63081.1 - 2.3e-05 24.3 0.0 0.02 14.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 RJW63081.1 - 0.00011 22.1 0.8 0.00061 19.6 0.1 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 RJW63081.1 - 0.0017 17.7 0.2 0.0021 17.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 RJW63081.1 - 0.0024 17.4 0.2 0.0075 15.8 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 RJW63081.1 - 0.0053 16.8 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RJW63081.1 - 0.032 14.6 0.0 0.071 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RJW63081.1 - 0.16 12.2 0.0 0.57 10.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain PT PF04886.12 RJW63082.1 - 9.7e-24 82.6 23.6 1.6e+04 -4.4 23.6 8.4 1 1 0 1 1 1 0 PT repeat SLC35F PF06027.12 RJW63083.1 - 2.3e-59 201.4 24.6 1.6e-58 198.6 24.6 2.2 1 1 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 RJW63083.1 - 9.1e-08 32.4 35.2 0.00031 20.9 6.5 2.4 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 RJW63083.1 - 0.00018 20.6 2.8 0.00018 20.6 2.8 1.9 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like CBF PF03914.17 RJW63085.1 - 2.3e-16 60.3 0.2 3.1e-15 56.6 0.0 2.7 1 1 1 2 2 2 1 CBF/Mak21 family 7tm_1 PF00001.21 RJW63090.1 - 3.5e-39 134.7 6.4 3.5e-39 134.7 6.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW63090.1 - 3.8e-08 33.3 8.6 6e-08 32.6 8.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RJW63090.1 - 0.00026 20.8 3.4 0.0011 18.7 3.4 2.1 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 RJW63090.1 - 0.01 15.1 3.7 0.03 13.6 0.3 2.3 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw E1-E2_ATPase PF00122.20 RJW63091.1 - 0.004 16.7 3.0 1.4 8.4 0.2 2.3 2 0 0 2 2 2 2 E1-E2 ATPase DUF3663 PF12404.8 RJW63092.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase zf-C2H2 PF00096.26 RJW63094.1 - 3.6e-05 24.0 7.3 0.054 14.0 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW63094.1 - 0.019 15.3 0.1 0.28 11.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_6 PF14599.6 RJW63094.1 - 0.021 14.8 0.5 1.2 9.2 0.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon zf-C2H2_4 PF13894.6 RJW63094.1 - 0.021 15.6 16.2 0.025 15.4 1.6 3.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RJW63094.1 - 0.33 10.6 5.8 0.19 11.4 0.3 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF35_N PF12172.8 RJW63094.1 - 0.34 10.8 3.9 1 9.3 1.0 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) NCD3G PF07562.14 RJW63098.1 - 0.1 12.6 0.6 0.1 12.6 0.6 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Dynein_light PF01221.18 RJW63099.1 - 9.3e-13 48.3 0.0 2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 SNURF PF07192.11 RJW63099.1 - 0.034 14.0 1.6 0.11 12.3 1.6 1.9 1 0 0 1 1 1 0 SNURF/RPN4 protein FERM_C PF09380.10 RJW63100.1 - 5.2e-18 65.2 0.0 1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RJW63100.1 - 4.9e-16 59.2 0.1 9.1e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 RJW63100.1 - 5.3e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain MIR PF02815.19 RJW63101.1 - 0.029 14.2 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 MIR domain DUF3416 PF11896.8 RJW63101.1 - 0.03 14.6 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Mucin_bdg PF03272.13 RJW63103.1 - 0.073 13.1 0.0 0.081 13.0 0.0 1.0 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module PHM7_ext PF12621.8 RJW63104.1 - 0.11 12.6 1.0 0.43 10.8 0.2 2.2 2 0 0 2 2 2 0 Extracellular tail, of 10TM putative phosphate transporter Sulfotransfer_3 PF13469.6 RJW63105.1 - 1.5e-21 77.8 0.3 1.9e-21 77.5 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RJW63105.1 - 0.14 11.6 0.3 0.32 10.5 0.3 1.6 1 1 0 1 1 1 0 Sulfotransferase domain Ig_2 PF13895.6 RJW63107.1 - 6e-06 26.5 0.0 0.22 11.9 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain TSP_1 PF00090.19 RJW63107.1 - 2.4e-05 24.5 17.5 0.0051 17.0 6.9 3.1 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_3 PF13927.6 RJW63107.1 - 0.002 18.7 0.7 0.04 14.5 0.0 3.5 3 1 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 RJW63107.1 - 0.015 15.5 0.7 0.31 11.2 0.1 3.5 3 1 0 3 3 3 0 Immunoglobulin domain V-set PF07686.17 RJW63107.1 - 0.018 15.2 0.0 1.1 9.5 0.1 3.1 3 1 0 3 3 3 0 Immunoglobulin V-set domain DNA_ligase_A_M PF01068.21 RJW63108.1 - 2.7e-55 187.2 0.0 4.8e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 RJW63108.1 - 1.1e-41 143.1 4.2 3.8e-30 105.5 2.1 2.6 2 0 0 2 2 2 2 DNA ligase N terminus RVT_1 PF00078.27 RJW63108.1 - 5.3e-39 134.0 0.0 1.2e-38 132.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_ligase_A_C PF04679.15 RJW63108.1 - 6e-17 62.1 0.0 2e-16 60.4 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 RJW63108.1 - 5.8e-06 26.7 0.0 1.3e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 RNA ligase Exo_endo_phos PF03372.23 RJW63108.1 - 0.0005 19.7 0.1 0.0042 16.6 0.1 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family B2-adapt-app_C PF09066.10 RJW63108.1 - 0.013 15.6 0.1 9.5 6.4 0.0 2.7 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain DUF2656 PF10847.8 RJW63108.1 - 0.058 13.5 0.0 0.93 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) Dynamin_N PF00350.23 RJW63109.1 - 7.3e-40 136.8 0.1 1.9e-39 135.4 0.1 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RJW63109.1 - 1.1e-05 25.5 0.5 5.6e-05 23.2 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 RJW63109.1 - 1.3e-05 24.6 1.2 0.00012 21.4 0.1 2.9 3 0 0 3 3 3 1 Dynamin central region DUF1593 PF07632.11 RJW63109.1 - 0.0022 17.5 0.0 0.01 15.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1593) FeoB_N PF02421.18 RJW63109.1 - 0.0037 16.8 0.1 0.4 10.2 0.1 2.5 1 1 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 RJW63109.1 - 0.0052 17.0 0.0 0.7 10.1 0.0 3.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 RJW63109.1 - 0.024 13.9 0.0 0.27 10.5 0.0 2.4 2 0 0 2 2 2 0 AIG1 family DUF327 PF03885.13 RJW63109.1 - 0.054 13.5 0.2 0.54 10.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF327) AAA_16 PF13191.6 RJW63109.1 - 0.12 12.8 4.0 0.37 11.2 0.0 3.5 3 2 0 4 4 4 0 AAA ATPase domain Shugoshin_N PF07558.11 RJW63109.1 - 0.31 11.0 2.7 1.2 9.1 2.7 2.1 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Glyco_trans_1_2 PF13524.6 RJW63109.1 - 0.45 10.9 2.9 14 6.1 0.1 3.8 4 0 0 4 4 4 0 Glycosyl transferases group 1 Homeodomain PF00046.29 RJW63110.1 - 6.4e-19 67.5 5.0 1.3e-18 66.6 5.0 1.5 1 0 0 1 1 1 1 Homeodomain Lir1 PF07207.11 RJW63110.1 - 8.9 6.6 9.3 0.27 11.5 0.2 3.1 3 0 0 3 3 3 0 Light regulated protein Lir1 TMEM100 PF16311.5 RJW63112.1 - 0.0092 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 100 LapA_dom PF06305.11 RJW63112.1 - 0.042 13.7 0.1 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 RJW63112.1 - 0.21 11.4 1.8 0.36 10.6 1.8 1.3 1 0 0 1 1 1 0 Vpu protein PDEase_I PF00233.19 RJW63115.1 - 7.2e-38 130.6 0.5 1e-37 130.1 0.5 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Mx_ML PF17536.2 RJW63115.1 - 0.051 13.3 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal PTS_EIIA_1 PF00358.20 RJW63115.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 T2SSE PF00437.20 RJW63116.1 - 0.00013 21.1 0.0 0.00024 20.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 RJW63116.1 - 0.051 13.9 0.1 0.22 11.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 RJW63116.1 - 0.061 13.2 1.0 1.9 8.3 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 RJW63116.1 - 1.4 9.4 0.0 1.4 9.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain cwf21 PF08312.12 RJW63118.1 - 0.049 13.8 1.2 0.14 12.4 1.2 1.8 1 0 0 1 1 1 0 cwf21 domain cNMP_binding PF00027.29 RJW63118.1 - 0.054 13.6 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain SNRNP27 PF08648.12 RJW63120.1 - 2.9e-29 100.9 0.9 5.3e-29 100.1 0.9 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Recombinase PF07508.13 RJW63120.1 - 0.11 12.8 0.1 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Recombinase Ion_trans PF00520.31 RJW63121.1 - 1.2e-30 106.5 14.9 1.6e-30 106.1 14.9 1.1 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 RJW63121.1 - 3.2e-16 59.5 0.0 6.2e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain Ion_trans_2 PF07885.16 RJW63121.1 - 9.6e-10 38.3 0.5 9.6e-10 38.3 0.5 2.3 2 0 0 2 2 2 1 Ion channel PAS PF00989.25 RJW63121.1 - 3.7e-07 30.1 0.0 7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 RJW63121.1 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 RJW63121.1 - 1.1e-05 25.7 0.0 3e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 PAS fold cNMP_binding PF00027.29 RJW63121.1 - 6.7e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EI24 PF07264.11 RJW63121.1 - 3.8 7.7 10.2 0.042 14.1 2.5 1.6 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DNA_ligase_A_M PF01068.21 RJW63122.1 - 5.1e-35 121.0 0.0 9.3e-35 120.1 0.0 1.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 RJW63122.1 - 1.1e-28 100.8 0.0 2.5e-28 99.6 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 RJW63122.1 - 1.2e-12 48.0 0.0 5.6e-11 42.7 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 RJW63122.1 - 1.4e-12 48.1 0.0 3.6e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 RJW63122.1 - 5.4e-07 29.9 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 RJW63122.1 - 0.00018 21.5 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 DNA ligase IV SET PF00856.28 RJW63123.1 - 2.5e-08 34.5 0.0 3.3e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 SET domain TPR_2 PF07719.17 RJW63123.1 - 1.1e-07 31.4 3.1 0.16 12.1 0.0 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 RJW63123.1 - 0.0003 20.5 0.4 0.46 10.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-MYND PF01753.18 RJW63123.1 - 0.0012 18.8 9.8 0.0012 18.8 9.8 2.6 2 0 0 2 2 2 1 MYND finger TPR_16 PF13432.6 RJW63123.1 - 0.14 12.8 2.6 62 4.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW63123.1 - 0.19 12.4 0.2 0.96 10.2 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat SET PF00856.28 RJW63124.1 - 7.6e-10 39.4 0.0 9e-09 35.9 0.0 2.5 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 RJW63124.1 - 0.00014 21.7 4.5 0.55 10.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW63124.1 - 0.0013 19.0 3.7 0.5 10.7 1.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RJW63124.1 - 0.0014 18.3 2.6 0.97 9.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-MYND PF01753.18 RJW63124.1 - 0.0032 17.5 8.7 0.0032 17.5 8.7 3.3 2 0 0 2 2 2 1 MYND finger RecO_C PF02565.15 RJW63124.1 - 0.059 13.2 0.1 0.21 11.4 0.1 1.9 1 0 0 1 1 1 0 Recombination protein O C terminal TPR_8 PF13181.6 RJW63124.1 - 0.085 13.1 0.1 3.1 8.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Pap_E4 PF02711.14 RJW63124.1 - 0.52 11.3 4.5 1.6 9.7 2.1 2.6 2 0 0 2 2 2 0 E4 protein Myc-LZ PF02344.15 RJW63125.1 - 0.034 14.2 1.3 0.061 13.4 1.3 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain DUF2773 PF10971.8 RJW63125.1 - 0.091 12.9 0.2 8.3 6.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2773) CSD PF00313.22 RJW63126.1 - 2.8e-26 91.1 0.4 5.7e-26 90.2 0.4 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain S1 PF00575.23 RJW63126.1 - 0.0095 16.3 0.2 0.017 15.4 0.2 1.3 1 0 0 1 1 1 1 S1 RNA binding domain eIF2A PF08662.11 RJW63128.1 - 1.7e-34 119.4 0.1 7.5e-18 65.1 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A SRF-TF PF00319.18 RJW63129.1 - 2.8e-16 58.7 0.1 5.9e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Peptidase_C65 PF10275.9 RJW63130.1 - 1.1e-68 231.4 0.0 1.6e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain TMEM131_like PF12371.8 RJW63130.1 - 0.0016 18.7 0.1 4.6 7.6 0.0 3.3 3 0 0 3 3 3 2 Transmembrane protein 131-like FYTT PF07078.11 RJW63131.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Forty-two-three protein zf-A20 PF01754.16 RJW63132.1 - 2.4e-11 43.3 5.8 9.2e-11 41.5 5.8 2.0 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 RJW63132.1 - 6.2e-09 35.9 6.4 6.2e-09 35.9 6.4 2.6 2 1 1 3 3 3 1 AN1-like Zinc finger NAM-associated PF14303.6 RJW63132.1 - 1.8 9.3 6.8 3.3 8.4 6.8 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Robl_LC7 PF03259.17 RJW63133.1 - 3.5e-13 49.1 0.0 4.3e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Dynein_light PF01221.18 RJW63134.1 - 9.5e-28 96.4 0.2 1.1e-27 96.2 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RuBisCO_large_N PF02788.16 RJW63134.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Ribonuclease_3 PF00636.26 RJW63136.1 - 0.0075 16.9 0.0 0.012 16.2 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease III domain Dynein_light PF01221.18 RJW63137.1 - 2.1e-25 88.8 0.0 2.3e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 RJW63137.1 - 0.055 12.9 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Pkinase PF00069.25 RJW63143.1 - 4.5e-40 137.7 0.0 5.8e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63143.1 - 7.4e-25 87.7 0.0 1.1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 RJW63143.1 - 4.3e-11 42.9 0.0 9.4e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain RVT_1 PF00078.27 RJW63143.1 - 1.3e-05 24.8 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kinase-like PF14531.6 RJW63143.1 - 0.0015 17.9 0.0 0.0031 16.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 RJW63143.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RJW63143.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 RJW63143.1 - 0.22 11.1 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DAGK_acc PF00609.19 RJW63145.1 - 3.9e-50 170.3 0.0 6e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 RJW63145.1 - 2.1e-19 69.4 0.0 5.9e-19 67.9 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 RJW63145.1 - 4.2e-12 45.8 12.4 8.7e-12 44.7 12.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RA PF00788.23 RJW63145.1 - 1.8e-10 41.3 0.1 3.3e-05 24.4 0.0 2.7 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain C1_2 PF03107.16 RJW63145.1 - 0.72 10.2 6.4 1.7 9.0 6.4 1.6 1 0 0 1 1 1 0 C1 domain Frizzled PF01534.17 RJW63147.1 - 9.6e-125 415.9 11.7 1.7e-124 415.1 11.7 1.4 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 RJW63147.1 - 6.4e-40 136.2 1.3 1.5e-39 135.1 1.3 1.7 1 0 0 1 1 1 1 Fz domain Tetraspanin PF00335.20 RJW63148.1 - 3.2e-28 99.0 6.7 3.5e-28 98.9 6.7 1.1 1 0 0 1 1 1 1 Tetraspanin family RecT PF03837.14 RJW63148.1 - 0.16 11.5 0.0 0.47 9.9 0.0 1.7 2 0 0 2 2 2 0 RecT family MTABC_N PF16185.5 RJW63148.1 - 0.57 9.6 6.4 0.75 9.2 6.4 1.1 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Pox_A14 PF05767.12 RJW63148.1 - 1 9.5 11.6 0.064 13.4 3.7 2.2 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF2569 PF10754.9 RJW63148.1 - 2.7 8.4 10.8 20 5.6 9.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF1218 PF06749.12 RJW63148.1 - 5.8 7.5 14.2 0.81 10.2 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) G-alpha PF00503.20 RJW63149.1 - 2.9e-56 191.2 3.7 4.4e-56 190.6 3.7 1.2 1 0 0 1 1 1 1 G-protein alpha subunit RVT_1 PF00078.27 RJW63149.1 - 1.4e-41 142.4 0.0 2.9e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arf PF00025.21 RJW63149.1 - 5.2e-08 32.5 0.2 1.5e-07 31.0 0.2 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family ITAM PF02189.15 RJW63149.1 - 0.15 12.6 0.5 1.1 9.9 0.1 2.3 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif UCH PF00443.29 RJW63150.1 - 1.6e-66 224.4 0.5 2.6e-66 223.8 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW63150.1 - 1.4e-18 67.6 0.2 3.8e-17 62.9 0.2 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Whib PF02467.16 RJW63150.1 - 0.19 12.3 0.6 0.47 11.1 0.6 1.6 1 0 0 1 1 1 0 Transcription factor WhiB RVT_1 PF00078.27 RJW63152.1 - 5.3e-14 52.3 0.0 7.1e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mu-conotoxin PF05374.12 RJW63154.1 - 1.7 8.7 12.8 8.6 6.5 2.6 2.8 2 0 0 2 2 2 0 Mu-Conotoxin Pkinase PF00069.25 RJW63157.1 - 0.00063 19.2 0.1 0.00094 18.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain MULE PF10551.9 RJW63158.1 - 1.3e-06 28.7 0.0 3.8e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain Arm PF00514.23 RJW63159.1 - 5.6e-13 48.4 20.0 0.00024 21.0 0.1 7.1 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat SAMP PF05924.11 RJW63159.1 - 4.7e-10 38.4 7.2 0.00052 19.2 0.3 4.1 3 0 0 3 3 3 3 SAMP Motif APC_rep PF18797.1 RJW63159.1 - 0.11 13.4 0.0 0.42 11.6 0.0 2.1 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat APC_r PF05923.12 RJW63159.1 - 0.13 12.0 11.9 0.41 10.4 0.5 5.4 4 0 0 4 4 4 0 APC repeat Flavodoxin_1 PF00258.25 RJW63161.1 - 9.4e-18 64.8 0.0 1.3e-15 57.9 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin NIF3 PF01784.18 RJW63162.1 - 2.1e-66 224.0 0.0 2.7e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Rrp44_S1 PF17215.3 RJW63162.1 - 0.2 11.6 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 S1 domain Ion_trans_N PF08412.10 RJW63166.1 - 2e-25 88.1 0.3 4.2e-25 87.1 0.3 1.6 1 0 0 1 1 1 1 Ion transport protein N-terminal Lectin_C PF00059.21 RJW63167.1 - 0.023 15.4 0.0 0.023 15.4 0.0 2.3 3 0 0 3 3 3 0 Lectin C-type domain RP-C_C PF11800.8 RJW63167.1 - 0.27 11.3 6.6 0.63 10.1 6.6 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region Mago-bind PF09282.10 RJW63168.1 - 1.8e-14 53.3 0.5 1.8e-14 53.3 0.5 2.0 2 0 0 2 2 2 1 Mago binding DUF3545 PF12065.8 RJW63168.1 - 0.0074 16.3 1.6 0.0074 16.3 1.6 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3545) PET PF06297.14 RJW63168.1 - 0.01 16.1 0.0 0.033 14.5 0.0 1.9 1 0 0 1 1 1 0 PET Domain IFT46_B_C PF12317.8 RJW63172.1 - 1.1e-62 211.6 0.2 1.3e-62 211.3 0.2 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Cwf_Cwc_15 PF04889.12 RJW63172.1 - 0.011 15.5 5.2 0.018 14.8 5.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 RJW63172.1 - 0.012 15.9 7.0 0.022 15.2 7.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 RJW63172.1 - 0.048 13.0 3.0 0.06 12.7 3.0 1.2 1 0 0 1 1 1 0 NOA36 protein Tim54 PF11711.8 RJW63172.1 - 0.076 11.8 0.2 0.11 11.2 0.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GCIP PF13324.6 RJW63172.1 - 0.15 11.6 0.6 0.21 11.2 0.6 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRN3 PF05327.11 RJW63172.1 - 0.28 9.7 2.0 0.26 9.8 0.9 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4611 PF15387.6 RJW63172.1 - 0.3 11.3 5.1 0.83 9.9 5.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Rhabdo_ncap PF00945.18 RJW63172.1 - 0.37 9.6 1.1 0.56 9.0 1.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein FAM176 PF14851.6 RJW63172.1 - 0.57 9.8 2.9 0.56 9.9 1.5 1.7 2 0 0 2 2 2 0 FAM176 family Pox_Ag35 PF03286.14 RJW63172.1 - 1.9 8.2 6.2 4.6 7.0 6.2 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 RJW63172.1 - 3.6 5.6 7.7 5.9 4.9 7.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 RJW63172.1 - 6 7.3 11.8 1.3 9.5 6.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CUB PF00431.20 RJW63173.1 - 4.7e-44 149.2 0.0 2.2e-14 53.7 0.0 4.0 4 0 0 4 4 4 4 CUB domain XS PF03468.14 RJW63173.1 - 0.021 15.1 0.0 8.3 6.7 0.0 2.5 2 0 0 2 2 2 0 XS domain Cupin_5 PF06172.11 RJW63173.1 - 0.11 12.7 0.0 21 5.2 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily (DUF985) PQQ PF01011.21 RJW63173.1 - 0.16 12.0 0.1 44 4.3 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat Peptidase_C14 PF00656.22 RJW63176.1 - 1.5e-41 143.0 0.0 1.8e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CybS PF05328.12 RJW63177.1 - 3.8e-24 84.9 0.1 4.4e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DUF2165 PF09933.9 RJW63178.1 - 0.078 13.0 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) BPL_N PF09825.9 RJW63178.1 - 0.23 10.5 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Dynein_light PF01221.18 RJW63180.1 - 3.1e-36 123.5 0.3 3.4e-36 123.4 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 W2 PF02020.18 RJW63181.1 - 1.7e-14 53.7 0.3 3.7e-14 52.6 0.3 1.5 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 RJW63181.1 - 4.4e-05 23.2 0.0 8.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 RJW63181.1 - 5.6e-05 22.7 1.8 0.024 14.4 0.4 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 RJW63181.1 - 0.0011 19.3 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 RJW63181.1 - 0.075 11.1 0.1 0.29 9.2 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) SesA PF17107.5 RJW63181.1 - 0.17 12.1 0.4 35 4.6 0.0 2.9 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FRG1 PF06229.12 RJW63182.1 - 5.8e-61 205.5 0.0 1.1e-60 204.7 0.0 1.4 2 0 0 2 2 2 1 FRG1-like domain DUF1754 PF08555.10 RJW63182.1 - 0.00046 20.9 4.9 0.00046 20.9 4.9 1.6 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) G-alpha PF00503.20 RJW63183.1 - 4.6e-49 167.5 0.1 6.9e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Exo_endo_phos_2 PF14529.6 RJW63183.1 - 0.01 15.7 0.0 0.04 13.8 0.0 1.9 1 1 1 2 2 2 0 Endonuclease-reverse transcriptase Arf PF00025.21 RJW63183.1 - 0.16 11.4 0.1 0.37 10.2 0.1 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family FERM_M PF00373.18 RJW63184.1 - 4.4e-11 43.2 0.0 1e-10 42.0 0.0 1.7 1 1 0 1 1 1 1 FERM central domain FERM_N PF09379.10 RJW63184.1 - 1.9e-09 37.4 0.0 3.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 RJW63184.1 - 1.3e-08 35.1 0.3 3.3e-08 33.8 0.3 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Tubulin PF00091.25 RJW63185.1 - 2.1e-52 178.2 0.0 4e-52 177.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW63185.1 - 5.1e-25 88.1 0.0 1.2e-24 86.9 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Dynein_light PF01221.18 RJW63187.1 - 2e-38 130.6 1.2 2.2e-38 130.4 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Rdx PF10262.9 RJW63189.1 - 5.7e-05 23.2 0.0 6.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Rdx family DUF3891 PF13030.6 RJW63190.1 - 0.065 13.0 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) Dynein_light PF01221.18 RJW63191.1 - 4.2e-29 100.7 0.7 5.9e-29 100.2 0.7 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Toxin_TOLIP PF00087.21 RJW63192.1 - 3.9e-05 23.8 13.7 6.9e-05 23.0 13.7 1.5 1 1 0 1 1 1 1 Snake toxin and toxin-like protein Activin_recp PF01064.23 RJW63192.1 - 0.29 12.2 11.1 0.52 11.4 11.1 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain Claudin_2 PF13903.6 RJW63194.1 - 1e-08 35.2 9.9 1.5e-08 34.7 9.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TMEM72 PF16054.5 RJW63195.1 - 0.055 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 72 Mto2_bdg PF12808.7 RJW63195.1 - 0.21 11.9 0.5 0.45 10.9 0.5 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Pkinase PF00069.25 RJW63196.1 - 2.4e-53 181.2 0.0 3.1e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63196.1 - 2.8e-28 98.9 0.0 3.3e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW63196.1 - 2e-07 30.6 0.0 4.3e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RJW63196.1 - 4.1e-06 26.5 0.0 5.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RJW63196.1 - 0.00021 20.7 0.3 0.00036 20.0 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RJW63196.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 RJW63196.1 - 0.02 14.8 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RJW63196.1 - 0.021 13.6 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 RJW63196.1 - 0.093 12.3 0.5 0.24 11.0 0.2 1.6 1 1 0 2 2 2 0 Choline/ethanolamine kinase CUB PF00431.20 RJW63197.1 - 2.1e-22 79.5 0.1 4.6e-15 55.9 0.1 2.1 2 0 0 2 2 2 2 CUB domain Med9 PF07544.13 RJW63198.1 - 0.84 9.8 5.7 3 8.0 3.2 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.12 RJW63198.1 - 4.6 7.9 6.7 0.93 10.2 1.1 2.7 3 0 0 3 3 3 0 SlyX NAD_binding_1 PF00175.21 RJW63199.1 - 7.2e-12 45.9 0.0 1.2e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 RJW63199.1 - 8.1e-12 45.2 0.0 2.6e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Dynein_light PF01221.18 RJW63200.1 - 3.6e-32 110.5 0.5 4.1e-32 110.4 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Swm2 PF17083.5 RJW63200.1 - 0.017 15.1 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 WD40 PF00400.32 RJW63201.1 - 5e-38 128.4 7.0 1.1e-07 32.4 0.4 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW63201.1 - 1e-18 67.4 0.0 2.5e-05 24.5 0.0 5.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 RJW63201.1 - 1.5e-12 46.9 0.2 4.4e-12 45.4 0.2 1.9 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 RJW63201.1 - 1.2e-10 40.9 0.1 0.0067 15.4 0.0 4.3 4 1 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RJW63201.1 - 1.9e-06 26.8 0.0 0.57 8.8 0.0 4.4 1 1 3 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 RJW63201.1 - 0.045 13.1 0.0 0.61 9.3 0.0 2.5 1 1 0 1 1 1 0 WD40-like domain T-box_assoc PF16176.5 RJW63201.1 - 0.11 12.5 0.4 0.25 11.4 0.4 1.5 1 0 0 1 1 1 0 T-box transcription factor-associated PD40 PF07676.12 RJW63201.1 - 0.12 12.3 0.1 1.9 8.5 0.0 2.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nucleoside_tran PF01733.18 RJW63203.1 - 7.1e-62 209.6 20.5 4.9e-42 144.4 9.6 2.5 3 0 0 3 3 3 2 Nucleoside transporter RVT_1 PF00078.27 RJW63203.1 - 0.00059 19.4 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AGP PF06376.12 RJW63203.1 - 0.67 9.9 3.1 1.6 8.7 3.1 1.6 1 0 0 1 1 1 0 Arabinogalactan peptide DUF373 PF04123.13 RJW63203.1 - 3.7 6.9 11.7 7.7 5.8 11.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Btz PF09405.10 RJW63205.1 - 4.6e-06 26.9 1.8 4.6e-06 26.9 1.8 2.2 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding PHO4 PF01384.20 RJW63206.1 - 3.5e-69 233.4 0.0 4e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family AbrB PF05145.12 RJW63206.1 - 0.001 18.1 0.5 0.001 18.1 0.5 1.5 2 0 0 2 2 2 1 Transition state regulatory protein AbrB V-ATPase_G_2 PF16999.5 RJW63207.1 - 0.025 15.0 4.1 0.056 13.9 2.6 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Phasin_2 PF09361.10 RJW63207.1 - 3.1 8.1 11.1 5.3 7.4 0.4 3.4 3 1 1 4 4 4 0 Phasin protein CUB PF00431.20 RJW63209.1 - 5.6e-141 461.2 22.8 4.3e-17 62.5 0.1 10.1 10 0 0 10 10 10 10 CUB domain CUB_2 PF02408.20 RJW63209.1 - 8.5e-08 32.0 0.2 17 5.2 0.0 6.1 5 0 0 5 5 5 4 CUB-like domain LnmK_N_HDF PF18238.1 RJW63209.1 - 1.6e-05 24.8 0.1 2.8 7.7 0.0 3.8 3 0 0 3 3 3 3 LnmK N-terminal Hot Dog Fold domain GHL6 PF14871.6 RJW63209.1 - 0.00073 19.7 4.6 9.1 6.4 0.1 3.5 3 0 0 3 3 3 3 Hypothetical glycosyl hydrolase 6 PAD_N PF08526.10 RJW63209.1 - 0.015 15.6 0.0 8 6.9 0.0 3.4 3 0 0 3 3 3 0 Protein-arginine deiminase (PAD) N-terminal domain MJ1316 PF04457.12 RJW63209.1 - 0.017 15.9 0.0 1e+02 3.7 0.0 3.7 3 0 0 3 3 3 0 MJ1316 RNA cyclic group end recognition domain GDNF PF02351.16 RJW63209.1 - 0.38 11.8 10.0 44 5.1 0.2 5.0 5 0 0 5 5 5 0 GDNF/GAS1 domain Serpin PF00079.20 RJW63211.1 - 1e-97 327.8 0.0 1.2e-97 327.6 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Molybdopterin PF00384.22 RJW63214.1 - 3.7e-67 227.2 0.0 2.5e-66 224.4 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 RJW63214.1 - 1e-17 63.9 0.3 1.9e-17 63.1 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 RJW63214.1 - 3.5e-16 58.5 0.1 3.5e-16 58.5 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 RJW63214.1 - 3.1e-11 43.8 0.2 8.8e-11 42.3 0.2 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 RJW63214.1 - 2.5e-07 30.6 1.4 2.5e-07 30.6 1.4 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 RJW63214.1 - 0.0015 18.3 0.2 4.5 7.0 0.0 3.4 3 1 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 RJW63214.1 - 0.17 11.8 1.4 4.7 7.2 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Glycos_transf_4 PF00953.21 RJW63215.1 - 1.7e-32 112.6 14.6 1.7e-32 112.6 14.6 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 4 cNMP_binding PF00027.29 RJW63217.1 - 6.6e-21 74.2 0.0 1.8e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RJW63217.1 - 3.2e-18 65.9 13.7 6.6e-18 64.8 13.7 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW63217.1 - 0.0056 16.6 2.2 0.014 15.3 1.6 2.1 1 1 0 1 1 1 1 Ion channel Cyclin_N PF00134.23 RJW63218.1 - 1.1e-12 47.7 0.0 1.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 RJW63218.1 - 1.8e-10 41.4 0.0 1.8e-10 41.4 0.0 1.6 2 1 0 2 2 2 1 Cyclin DUF2733 PF10813.8 RJW63218.1 - 0.04 13.7 1.1 0.11 12.3 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) Serpin PF00079.20 RJW63219.1 - 1e-95 321.2 0.0 1.3e-95 320.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) HMG_box PF00505.19 RJW63221.1 - 1.2e-12 48.0 3.5 2.2e-12 47.2 3.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box DUF4819 PF16090.5 RJW63221.1 - 2.4e-07 30.7 0.1 3.2e-06 27.1 0.0 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4819) HMG_box_2 PF09011.10 RJW63221.1 - 6.7e-06 26.6 1.4 1.5e-05 25.5 1.4 1.6 1 0 0 1 1 1 1 HMG-box domain Beta-lactamase PF00144.24 RJW63223.1 - 8.8e-37 127.1 0.0 4.1e-36 124.9 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase Tetraspanin PF00335.20 RJW63223.1 - 9.5e-12 45.1 1.1 2e-11 44.1 1.1 1.5 1 0 0 1 1 1 1 Tetraspanin family Peptidase_S11 PF00768.20 RJW63223.1 - 0.046 13.2 0.0 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DUF2576 PF10845.8 RJW63223.1 - 0.069 12.8 0.5 0.37 10.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) DUF2534 PF10749.9 RJW63223.1 - 0.11 12.7 0.3 0.28 11.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) CybS PF05328.12 RJW63223.1 - 0.24 11.1 1.7 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit HARP PF07443.13 RJW63224.1 - 0.016 14.8 0.9 0.026 14.1 0.3 1.7 2 0 0 2 2 2 0 HepA-related protein (HARP) Sld5 PF05916.11 RJW63225.1 - 0.0014 19.1 0.1 0.0023 18.4 0.1 1.5 1 1 0 1 1 1 1 GINS complex protein DUF4603 PF15376.6 RJW63225.1 - 0.012 13.1 0.0 0.014 12.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) WD40 PF00400.32 RJW63226.1 - 0.0002 22.1 0.5 1.8 9.5 0.2 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-RING_2 PF13639.6 RJW63226.1 - 0.0017 18.6 12.2 0.14 12.5 4.3 2.8 2 0 0 2 2 2 2 Ring finger domain ANAPC4_WD40 PF12894.7 RJW63226.1 - 0.071 13.4 0.0 8.2 6.8 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-ANAPC11 PF12861.7 RJW63226.1 - 1 9.5 6.5 2.9 8.0 6.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 RJW63226.1 - 1.7 8.6 11.0 2.9 7.8 0.5 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW63226.1 - 2.9 8.0 13.1 0.35 10.9 8.0 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 RJW63226.1 - 5 7.2 12.0 87 3.2 12.0 2.5 1 1 0 1 1 1 0 zinc-RING finger domain AA_permease_2 PF13520.6 RJW63227.1 - 2.3e-29 102.5 13.3 2.3e-29 102.5 13.3 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 RJW63227.1 - 1.6e-21 76.5 11.4 1.6e-21 76.5 11.4 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RJW63227.1 - 3.9e-20 71.7 8.7 3.9e-20 71.7 8.7 4.0 4 0 0 4 4 4 1 C-terminus of AA_permease Saf_2TM PF18303.1 RJW63227.1 - 0.13 11.8 1.4 0.39 10.3 1.4 1.8 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain PRT_C PF08372.10 RJW63227.1 - 0.76 9.5 2.6 0.92 9.3 0.2 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Arf PF00025.21 RJW63231.1 - 1.8e-73 245.7 0.0 2.2e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RJW63231.1 - 1.1e-14 54.7 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RJW63231.1 - 2.9e-13 49.8 0.0 3.5e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 RJW63231.1 - 4.3e-10 39.3 0.5 7.2e-07 28.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 RJW63231.1 - 6.1e-10 38.8 0.0 7.5e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RJW63231.1 - 4.3e-09 36.1 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RJW63231.1 - 7.5e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RJW63231.1 - 0.0017 17.9 0.2 0.025 14.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 RJW63231.1 - 0.005 16.6 0.1 3.4 7.4 0.0 2.5 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 RJW63231.1 - 0.0095 16.5 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RJW63231.1 - 0.014 15.3 0.0 4.1 7.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 RJW63231.1 - 0.015 14.3 0.1 0.74 8.7 0.0 2.4 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 RJW63231.1 - 0.087 13.3 0.2 0.19 12.3 0.2 1.7 1 1 0 1 1 1 0 ABC transporter cobW PF02492.19 RJW63231.1 - 0.13 11.8 0.3 13 5.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 RJW63231.1 - 0.14 12.6 0.1 0.34 11.3 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain UQ_con PF00179.26 RJW63232.1 - 1.2e-19 70.3 0.0 1.8e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RJW63232.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Myosin_tail_1 PF01576.19 RJW63234.1 - 2e-75 254.4 166.7 3.3e-75 253.7 166.7 1.4 1 1 0 1 1 1 1 Myosin tail Filament PF00038.21 RJW63234.1 - 8.5e-21 74.8 144.9 2.2e-06 27.5 35.1 7.0 1 1 4 6 6 6 5 Intermediate filament protein ATG16 PF08614.11 RJW63234.1 - 6.5e-06 26.5 177.8 0.013 15.8 17.2 9.1 1 1 6 8 8 8 6 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 RJW63234.1 - 3.8e-05 21.5 58.0 3.8e-05 21.5 58.0 4.3 1 1 3 4 4 4 1 Protein of unknown function (DUF3584) HMMR_N PF15905.5 RJW63234.1 - 4.9e-05 23.0 19.8 4.9e-05 23.0 19.8 6.1 1 1 5 6 6 6 3 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 RJW63234.1 - 9.4e-05 21.4 29.7 9.4e-05 21.4 29.7 7.2 1 1 6 7 7 7 4 Spc7 kinetochore protein DUF1664 PF07889.12 RJW63234.1 - 0.00015 21.8 87.7 0.087 12.9 1.2 10.9 2 2 10 13 13 13 4 Protein of unknown function (DUF1664) ADIP PF11559.8 RJW63234.1 - 0.0002 21.5 13.6 0.0002 21.5 13.6 11.0 2 2 9 11 11 11 3 Afadin- and alpha -actinin-Binding TolA_bind_tri PF16331.5 RJW63234.1 - 0.0004 20.4 4.1 0.0004 20.4 4.1 14.4 6 4 8 14 14 14 5 TolA binding protein trimerisation Shugoshin_N PF07558.11 RJW63234.1 - 0.0007 19.4 40.9 0.0041 16.9 0.3 8.2 8 0 0 8 8 8 3 Shugoshin N-terminal coiled-coil region Rab5-bind PF09311.11 RJW63234.1 - 0.0012 18.3 36.3 0.0012 18.3 36.3 7.4 1 1 5 7 7 6 1 Rabaptin-like protein Fib_alpha PF08702.10 RJW63234.1 - 0.0016 18.6 4.5 0.0016 18.6 4.5 9.2 1 1 9 10 10 10 2 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 RJW63234.1 - 0.002 18.0 2.5 0.002 18.0 2.5 11.8 6 5 5 13 13 13 1 GIT coiled-coil Rho guanine nucleotide exchange factor HOOK PF05622.12 RJW63234.1 - 0.0023 16.2 20.3 0.0023 16.2 20.3 5.1 1 1 4 5 5 4 3 HOOK protein KASH_CCD PF14662.6 RJW63234.1 - 0.003 17.4 21.5 0.003 17.4 21.5 8.2 1 1 5 7 7 7 4 Coiled-coil region of CCDC155 or KASH HR1 PF02185.16 RJW63234.1 - 0.0036 17.4 9.6 0.0036 17.4 9.6 11.9 5 4 5 10 10 6 1 Hr1 repeat JIP_LZII PF16471.5 RJW63234.1 - 0.005 17.0 8.0 0.005 17.0 8.0 14.5 4 2 15 20 20 19 3 JNK-interacting protein leucine zipper II ZapB PF06005.12 RJW63234.1 - 0.014 15.8 5.7 0.014 15.8 5.7 14.4 4 4 7 11 11 8 0 Cell division protein ZapB CHDCT2 PF08074.11 RJW63234.1 - 0.015 15.5 6.8 0.015 15.5 6.8 7.2 3 2 6 9 9 9 0 CHDCT2 (NUC038) domain NumbF PF06311.12 RJW63234.1 - 0.086 13.4 0.3 0.086 13.4 0.3 6.4 5 2 0 6 6 5 0 NUMB domain TSC22 PF01166.18 RJW63234.1 - 0.089 13.1 0.3 0.089 13.1 0.3 10.9 6 3 5 12 12 12 0 TSC-22/dip/bun family Uso1_p115_C PF04871.13 RJW63234.1 - 2.2 8.6 155.2 0.48 10.8 10.3 11.4 1 1 8 9 9 8 0 Uso1 / p115 like vesicle tethering protein, C terminal region YqjK PF13997.6 RJW63234.1 - 3.3 8.0 8.7 14 6.0 0.5 3.9 3 1 1 4 4 3 0 YqjK-like protein AAA_13 PF13166.6 RJW63234.1 - 8.8 4.8 115.5 0.0091 14.7 22.8 5.4 1 1 4 5 5 5 0 AAA domain HAUS-augmin3 PF14932.6 RJW63234.1 - 8.9 5.8 133.5 0.76 9.3 11.4 9.5 1 1 9 10 10 10 0 HAUS augmin-like complex subunit 3 DEAD PF00270.29 RJW63235.1 - 2.1e-49 167.7 0.0 3.4e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW63235.1 - 1.8e-30 105.5 0.0 3.8e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HTH_OrfB_IS605 PF12323.8 RJW63236.1 - 0.033 13.7 0.2 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain SapB_1 PF05184.15 RJW63236.1 - 0.068 13.2 0.1 0.068 13.2 0.1 3.2 3 1 0 3 3 3 0 Saposin-like type B, region 1 zf-LSD1 PF06943.12 RJW63236.1 - 1.1 9.2 0.1 1.1 9.2 0.1 3.4 4 0 0 4 4 4 0 LSD1 zinc finger TBPIP PF07106.13 RJW63237.1 - 3.2e-17 62.2 0.3 6.1e-17 61.3 0.3 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 RJW63237.1 - 1.5e-06 28.2 0.1 3.1e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Uso1_p115_C PF04871.13 RJW63237.1 - 0.0048 17.3 3.3 0.0087 16.4 3.3 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Baculo_PEP_C PF04513.12 RJW63237.1 - 0.006 16.6 1.7 0.006 16.6 1.7 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4349 PF14257.6 RJW63237.1 - 0.021 14.3 4.6 0.036 13.5 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) GPS2_interact PF15784.5 RJW63237.1 - 0.038 14.4 0.9 0.087 13.3 0.9 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KELK PF15796.5 RJW63237.1 - 0.065 13.7 5.3 0.16 12.4 5.3 1.6 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1192 PF06698.11 RJW63237.1 - 0.087 12.9 8.2 1.1 9.4 2.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF2730 PF10805.8 RJW63237.1 - 0.094 12.8 2.3 0.19 11.8 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF910 PF06014.11 RJW63237.1 - 0.12 12.4 1.8 24 5.1 0.1 4.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF910) SlyX PF04102.12 RJW63237.1 - 0.25 12.0 3.7 1.1 9.9 2.2 2.5 1 1 1 2 2 2 0 SlyX Lzipper-MIP1 PF14389.6 RJW63237.1 - 2.4 8.5 9.8 2.1 8.7 8.0 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 CCDC-167 PF15188.6 RJW63237.1 - 6 7.3 9.9 4.5 7.7 1.4 2.5 2 1 1 3 3 2 0 Coiled-coil domain-containing protein 167 ABC_tran_CTD PF16326.5 RJW63237.1 - 9.5 6.5 10.6 23 5.3 7.7 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain TPMT PF05724.11 RJW63238.1 - 6.2e-43 147.0 0.0 7.6e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) EF-hand_13 PF17958.1 RJW63238.1 - 0.13 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain CNOT1_CAF1_bind PF16415.5 RJW63240.1 - 7.2e-47 159.6 0.4 8.1e-47 159.5 0.4 1.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain MIF4G PF02854.19 RJW63240.1 - 0.0045 16.7 0.8 0.021 14.5 0.8 2.0 1 1 0 1 1 1 1 MIF4G domain Symplekin_C PF12295.8 RJW63240.1 - 0.014 15.5 0.2 0.029 14.5 0.2 1.5 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal Acyl-CoA_dh_1 PF00441.24 RJW63242.1 - 3.2e-32 111.8 1.1 6.7e-32 110.8 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RJW63242.1 - 2.3e-21 75.8 0.0 4.4e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RJW63242.1 - 5.8e-18 65.6 0.0 1.4e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RJW63242.1 - 2.1e-10 41.0 0.0 5.3e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MdcE PF06833.11 RJW63242.1 - 0.1 12.1 0.0 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) LIM PF00412.22 RJW63243.1 - 1.3e-11 44.5 12.3 1.6e-11 44.3 12.3 1.1 1 0 0 1 1 1 1 LIM domain DpnI PF06044.12 RJW63243.1 - 0.012 15.3 2.6 0.013 15.1 2.6 1.1 1 0 0 1 1 1 0 Dam-replacing family UPAR_LY6_2 PF16975.5 RJW63243.1 - 0.44 10.8 8.3 0.53 10.5 6.3 1.8 1 1 1 2 2 2 0 Ly6/PLAUR domain-containing protein 6, Lypd6 FAT PF02259.23 RJW63244.1 - 7e-73 245.8 0.0 2.8e-61 207.7 0.0 2.5 2 0 0 2 2 2 2 FAT domain PI3_PI4_kinase PF00454.27 RJW63244.1 - 3.4e-70 236.7 0.3 5.9e-70 235.9 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 RJW63244.1 - 8.8e-33 112.7 1.1 4.3e-32 110.5 0.7 2.5 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 RJW63244.1 - 1.7e-10 40.6 0.1 4e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 RJW63244.1 - 0.0064 17.0 0.1 1.1 9.8 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW63244.1 - 0.05 14.4 3.9 0.33 11.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 RJW63244.1 - 0.09 12.9 2.3 10 6.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 RJW63245.1 - 6e-23 81.5 0.0 1.6e-13 50.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RJW63245.1 - 2.8e-06 27.4 0.0 0.14 12.1 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 RJW63245.1 - 1.9e-05 24.4 0.1 0.014 15.0 0.1 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 RJW63245.1 - 0.00026 20.0 0.1 0.0027 16.6 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 RJW63245.1 - 0.00045 19.4 0.0 0.0007 18.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 RJW63245.1 - 0.0011 19.5 0.2 0.4 11.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RJW63245.1 - 0.0052 17.0 0.1 0.014 15.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 RJW63245.1 - 0.02 14.1 0.0 0.28 10.4 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RJW63245.1 - 0.09 11.9 0.1 1.9 7.5 0.0 2.5 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 RJW63245.1 - 0.12 11.7 0.0 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 RJW63245.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 RJW63245.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Synaptobrevin PF00957.21 RJW63247.1 - 2.3e-32 110.6 3.5 5.3e-32 109.5 3.5 1.6 1 0 0 1 1 1 1 Synaptobrevin Sigma_reg_N PF13800.6 RJW63247.1 - 0.0099 16.2 0.5 0.024 14.9 0.5 1.6 1 0 0 1 1 1 1 Sigma factor regulator N-terminal DUF4736 PF15883.5 RJW63247.1 - 6.5 6.4 6.4 0.77 9.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Metallophos PF00149.28 RJW63248.1 - 2.8e-21 76.9 2.0 4.4e-21 76.3 1.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RJW63248.1 - 7.7e-20 71.5 0.1 2e-19 70.2 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 RJW63248.1 - 1.6e-19 70.3 0.0 2.7e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain UDPGP PF01704.18 RJW63249.1 - 2.1e-184 613.0 0.0 2.4e-184 612.8 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Bap31_Bap29_C PF18035.1 RJW63249.1 - 0.067 13.2 0.1 16 5.6 0.0 2.7 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain CDC50 PF03381.15 RJW63250.1 - 1.9e-20 73.6 0.1 2.7e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3810 PF12725.7 RJW63250.1 - 0.26 10.6 0.7 0.37 10.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) CTP_synth_N PF06418.14 RJW63251.1 - 7.5e-123 409.0 0.1 1e-122 408.6 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 RJW63251.1 - 5.2e-41 140.5 0.0 4.8e-33 114.5 0.0 2.6 2 1 0 2 2 2 2 Glutamine amidotransferase class-I Nop14 PF04147.12 RJW63253.1 - 3.2 5.8 28.1 3.6 5.7 28.1 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RJW63253.1 - 6.4 4.8 39.1 8.7 4.3 39.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Lamp PF01299.17 RJW63255.1 - 0.00041 20.2 2.5 7.2 6.4 0.0 3.8 4 0 0 4 4 4 3 Lysosome-associated membrane glycoprotein (Lamp) COX8 PF02285.15 RJW63255.1 - 0.011 15.6 0.1 0.036 14.0 0.1 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII HEAT PF02985.22 RJW63256.1 - 0.079 13.3 0.2 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat DUF4729 PF15866.5 RJW63257.1 - 0.72 9.1 11.3 11 5.3 5.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4729) zf-C2H2_aberr PF17017.5 RJW63257.1 - 3.7 7.7 7.8 4.5 7.4 0.1 3.0 2 1 1 3 3 3 0 Aberrant zinc-finger RVT_1 PF00078.27 RJW63258.1 - 7.7e-45 153.1 0.0 1.2e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW63258.1 - 4.8e-07 29.6 0.0 1.4e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW63258.1 - 5e-07 29.5 1.0 1.5e-06 27.9 0.4 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Metallophos PF00149.28 RJW63259.1 - 1e-40 140.4 0.1 1.3e-40 140.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RJW63259.1 - 7e-22 77.6 2.8 1.1e-21 77.0 2.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain TRAP-delta PF05404.12 RJW63260.1 - 8.1e-40 136.0 0.0 1e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) RRM_1 PF00076.22 RJW63261.1 - 7.5e-45 150.6 0.0 4.7e-19 68.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW63261.1 - 0.00012 22.1 0.0 0.67 10.1 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 RJW63261.1 - 0.0013 18.5 0.0 0.035 13.9 0.0 2.7 2 1 0 2 2 2 1 Occluded RNA-recognition motif PapC_C PF13953.6 RJW63261.1 - 0.14 12.0 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 PapC C-terminal domain LPP20 PF02169.16 RJW63261.1 - 9.9 6.6 8.1 2.2 8.7 0.5 2.5 2 0 0 2 2 2 0 LPP20 lipoprotein RVT_1 PF00078.27 RJW63265.1 - 3.6e-24 85.5 0.0 2.4e-23 82.8 0.0 2.1 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpb4 PF03874.16 RJW63265.1 - 1.5e-19 70.5 2.4 2.9e-19 69.6 2.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb4 SapB_1 PF05184.15 RJW63266.1 - 0.0051 16.8 0.0 0.049 13.7 0.0 2.5 2 0 0 2 2 2 1 Saposin-like type B, region 1 AMP-binding PF00501.28 RJW63268.1 - 7.1e-87 291.7 0.1 8.5e-87 291.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RJW63268.1 - 5.4e-21 75.4 0.1 1.4e-20 74.1 0.1 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain zf-RING_2 PF13639.6 RJW63270.1 - 1e-08 35.4 12.1 3e-08 33.9 12.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RJW63270.1 - 3e-07 30.6 7.3 1e-06 28.9 7.3 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RJW63270.1 - 3.4e-06 26.8 6.6 3.4e-06 26.8 6.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW63270.1 - 2.2e-05 24.2 10.1 5.1e-05 23.0 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW63270.1 - 6.6e-05 22.8 7.5 0.00017 21.5 7.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 RJW63270.1 - 0.00021 21.0 5.0 0.00021 21.0 5.0 3.2 3 0 0 3 3 3 1 RING-like zinc finger Prok-RING_4 PF14447.6 RJW63270.1 - 0.00037 20.3 8.5 0.00097 19.0 8.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RJW63270.1 - 0.00082 19.4 8.8 0.0014 18.6 5.6 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RJW63270.1 - 0.0011 18.8 9.7 0.0024 17.7 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RJW63270.1 - 0.011 15.8 2.4 0.031 14.3 2.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RJW63270.1 - 0.061 13.0 8.4 0.16 11.6 8.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type G2BR PF18442.1 RJW63270.1 - 0.16 11.7 2.5 0.28 10.8 2.5 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) zf-P11 PF03854.14 RJW63270.1 - 0.29 10.8 11.9 0.13 12.0 7.5 2.7 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 RJW63270.1 - 0.7 10.1 8.2 2 8.7 8.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 RJW63270.1 - 9.5 6.1 8.4 17 5.3 6.4 2.4 2 1 0 2 2 1 0 RING/Ubox like zinc-binding domain Kunitz_BPTI PF00014.23 RJW63271.1 - 1.8e-16 60.1 4.8 2.5e-16 59.6 4.8 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Pecanex_C PF05041.15 RJW63272.1 - 4.5e-98 327.4 0.0 9.3e-98 326.3 0.0 1.5 2 0 0 2 2 2 1 Pecanex protein (C-terminus) PH PF00169.29 RJW63272.1 - 0.015 15.8 0.2 0.042 14.4 0.2 1.7 1 0 0 1 1 1 0 PH domain GRDP-like PF07173.12 RJW63273.1 - 8.4e-22 78.4 1.8 9.3e-17 62.0 0.1 3.5 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like GAT PF03127.14 RJW63276.1 - 1.5e-21 76.4 0.9 2.9e-21 75.6 0.9 1.5 1 0 0 1 1 1 1 GAT domain YIF1 PF03878.15 RJW63277.1 - 1.2e-63 214.9 0.6 1.7e-63 214.4 0.6 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 RJW63277.1 - 2e-06 27.7 2.2 3.1e-06 27.0 2.2 1.3 1 0 0 1 1 1 1 Yip1 domain AA_permease_2 PF13520.6 RJW63278.1 - 3.4e-42 144.8 28.1 3.4e-42 144.8 28.1 3.0 2 1 1 3 3 3 2 Amino acid permease AA_permease PF00324.21 RJW63278.1 - 9.4e-27 93.7 27.4 9.4e-27 93.7 27.4 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RJW63278.1 - 1.2e-19 70.1 10.4 1.2e-19 70.1 10.4 4.7 7 0 0 7 7 7 1 C-terminus of AA_permease WBP-1 PF11669.8 RJW63278.1 - 0.12 13.0 1.1 12 6.6 0.2 3.0 2 0 0 2 2 2 0 WW domain-binding protein 1 Radial_spoke PF04712.12 RJW63279.1 - 1.5e-145 486.0 1.8 1.5e-145 486.0 1.8 2.0 1 1 1 2 2 2 1 Radial spokehead-like protein MIT_C PF16565.5 RJW63280.1 - 1.2e-50 171.1 0.0 1.9e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT MIT PF04212.18 RJW63280.1 - 0.00018 21.5 0.1 0.00034 20.6 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FERM_C PF09380.10 RJW63281.1 - 7.4e-21 74.3 0.3 1.4e-20 73.4 0.3 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 RJW63281.1 - 1.8e-12 47.0 0.1 3.5e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 RJW63281.1 - 5.9e-12 46.0 0.9 1e-11 45.3 0.3 1.7 2 0 0 2 2 2 1 FERM central domain Pou PF00157.17 RJW63282.1 - 2.4e-23 81.9 0.8 5.7e-23 80.7 0.1 2.0 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain MFS_1 PF07690.16 RJW63286.1 - 2e-48 165.1 46.3 2.3e-47 161.6 35.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RJW63286.1 - 1e-06 28.3 5.6 1e-06 28.3 5.6 2.6 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB CDC50 PF03381.15 RJW63287.1 - 2.2e-47 161.9 0.0 2.8e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family VEGF_C PF14554.6 RJW63287.1 - 0.13 12.4 0.3 0.25 11.5 0.3 1.4 1 0 0 1 1 1 0 VEGF heparin-binding domain PDZ PF00595.24 RJW63289.1 - 3.5e-05 24.1 0.0 7.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW63289.1 - 0.048 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 PDZ domain SAM_1 PF00536.30 RJW63291.1 - 4.1e-24 84.8 1.5 9.4e-10 38.8 0.1 4.2 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RJW63291.1 - 1.2e-21 76.6 0.1 4.8e-07 29.8 0.0 3.6 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) Filo_VP35 PF02097.15 RJW63291.1 - 0.034 13.2 0.4 0.094 11.8 0.4 1.7 1 0 0 1 1 1 0 Filoviridae VP35 EPO_TPO PF00758.18 RJW63291.1 - 0.16 12.0 2.9 0.37 10.8 1.3 2.6 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin DUF1932 PF09130.11 RJW63291.1 - 2.2 8.3 5.7 18 5.4 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1932) Metallophos_C PF14008.6 RJW63292.1 - 6.8e-23 81.3 0.1 2.3e-22 79.6 0.1 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 RJW63292.1 - 1.1e-22 81.6 1.5 1.6e-22 81.0 0.6 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 RJW63292.1 - 1.9e-19 70.0 0.1 4e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD PF09423.10 RJW63292.1 - 0.0046 16.0 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.7 RJW63292.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Corona_RPol_N PF06478.13 RJW63292.1 - 0.2 10.7 0.3 0.27 10.2 0.3 1.2 1 0 0 1 1 1 0 Coronavirus RPol N-terminus Rhomboid PF01694.22 RJW63293.1 - 2.4e-34 118.5 7.5 3.7e-34 117.9 7.5 1.2 1 0 0 1 1 1 1 Rhomboid family RVT_1 PF00078.27 RJW63295.1 - 2.8e-46 157.8 0.6 1.1e-45 155.9 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW63295.1 - 1.8e-11 43.9 0.0 8.1e-11 41.8 0.0 2.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase WD40 PF00400.32 RJW63295.1 - 0.00033 21.4 11.6 0.14 13.1 3.3 5.2 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW63295.1 - 0.016 15.5 0.0 0.12 12.7 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Dynein_attach_N PF15867.5 RJW63296.1 - 2.9e-27 94.4 0.0 5.7e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 RJW63296.1 - 5.6e-12 46.0 0.2 1.3e-11 44.9 0.2 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Antigen_Bd37 PF11641.8 RJW63296.1 - 0.11 12.0 0.3 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein TruB_C_2 PF16198.5 RJW63297.1 - 1.1e-23 83.2 0.6 2.2e-23 82.2 0.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DKCLD PF08068.12 RJW63297.1 - 5.2e-21 74.5 0.2 1.4e-20 73.1 0.2 1.8 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.18 RJW63297.1 - 6.3e-21 75.3 0.7 4e-18 66.2 0.7 3.0 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 RJW63297.1 - 1e-19 70.3 0.3 2.5e-19 69.0 0.3 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 RJW63297.1 - 0.022 15.0 0.0 0.096 13.0 0.0 2.1 2 0 0 2 2 2 0 UPF0113 PUA domain CUB PF00431.20 RJW63298.1 - 1.2e-50 170.5 0.0 4.7e-14 52.7 0.0 7.2 8 1 0 8 8 8 5 CUB domain Ldl_recept_a PF00057.18 RJW63298.1 - 0.012 15.8 1.9 0.036 14.3 1.9 1.9 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A DUF4477 PF14780.6 RJW63298.1 - 0.047 13.3 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Homeodomain PF00046.29 RJW63299.1 - 5.8e-23 80.5 6.6 2.5e-22 78.5 5.7 2.2 2 0 0 2 2 2 1 Homeodomain Pkinase PF00069.25 RJW63300.1 - 3.7e-61 206.8 0.0 5.7e-39 134.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63300.1 - 1.4e-27 96.6 0.0 1.1e-19 70.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RJW63300.1 - 8.8e-05 22.5 1.1 0.07 13.0 0.2 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW63300.1 - 0.0087 15.0 0.1 0.015 14.2 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RJW63300.1 - 0.021 14.2 0.1 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 RJW63300.1 - 0.026 13.5 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 RJW63300.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family AXH PF08517.12 RJW63301.1 - 1.7e-18 67.3 0.0 2e-16 60.6 0.0 2.5 1 1 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) RVT_1 PF00078.27 RJW63302.1 - 1.3e-11 44.4 0.0 4.5e-05 23.1 0.0 3.9 3 1 1 4 4 4 3 Reverse transcriptase (RNA-dependent DNA polymerase) T6PP_N PF18572.1 RJW63302.1 - 0.066 13.1 0.4 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Nefa_Nip30_N PF10187.9 RJW63303.1 - 2.8e-16 59.8 9.6 4.8e-16 59.0 9.6 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 zf-Di19 PF05605.12 RJW63304.1 - 0.00017 21.8 5.3 0.017 15.4 3.0 2.6 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 RJW63304.1 - 0.59 10.0 2.7 5.1 7.0 0.4 2.5 1 1 1 2 2 2 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 RJW63304.1 - 2.4 9.2 15.0 2.7 9.1 3.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Pkinase PF00069.25 RJW63305.1 - 1.2e-05 24.9 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63305.1 - 0.00091 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PPP1R32 PF15691.5 RJW63307.1 - 3.6e-36 125.2 11.7 4.9e-26 91.8 4.5 2.0 1 1 1 2 2 2 2 Protein phosphatase 1 regulatory subunit 32 Presenilin PF01080.17 RJW63308.1 - 0.88 8.3 7.1 1 8.0 7.1 1.1 1 0 0 1 1 1 0 Presenilin TP_methylase PF00590.20 RJW63310.1 - 1e-20 74.6 0.0 2.4e-20 73.4 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2303 PF10065.9 RJW63311.1 - 0.0032 16.7 0.0 0.0037 16.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2303) Na_K-ATPase PF00287.18 RJW63312.1 - 5.6e-25 88.1 0.0 7e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain AAA PF00004.29 RJW63313.1 - 1.6e-29 103.0 0.0 3.3e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW63313.1 - 1.8e-13 50.1 0.2 7.5e-13 48.1 0.2 2.1 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 RJW63313.1 - 4.8e-08 32.9 0.0 1.3e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 RJW63313.1 - 1.7e-05 25.3 0.1 0.022 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 RJW63313.1 - 5.7e-05 22.9 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RJW63313.1 - 0.00019 21.6 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RJW63313.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 RJW63313.1 - 0.00084 19.5 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RJW63313.1 - 0.0023 17.9 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RJW63313.1 - 0.0072 15.7 1.9 0.0086 15.5 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RJW63313.1 - 0.0075 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 RJW63313.1 - 0.0091 15.5 0.2 0.046 13.2 0.1 2.0 1 1 1 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 RJW63313.1 - 0.016 15.2 0.5 0.2 11.7 0.0 2.9 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 RJW63313.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 RJW63313.1 - 0.024 14.9 0.2 0.085 13.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 RJW63313.1 - 0.035 13.6 0.1 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Cytidylate_kin PF02224.18 RJW63313.1 - 0.038 13.7 0.3 2.3 7.9 0.1 2.4 2 0 0 2 2 2 0 Cytidylate kinase RNA_helicase PF00910.22 RJW63313.1 - 0.047 14.1 0.0 0.16 12.4 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.6 RJW63313.1 - 0.07 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RJW63313.1 - 0.092 12.5 0.1 1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RJW63313.1 - 0.11 12.8 0.3 0.24 11.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain DUF4296 PF14129.6 RJW63313.1 - 0.13 12.9 0.1 0.39 11.3 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4296) AAA_17 PF13207.6 RJW63313.1 - 0.16 12.4 0.0 0.46 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RJW63313.1 - 0.25 10.7 0.7 1.2 8.4 0.1 2.3 2 1 1 3 3 3 0 KaiC Snapin_Pallidin PF14712.6 RJW63315.1 - 0.018 15.4 3.5 0.14 12.6 0.0 2.9 2 1 0 2 2 2 0 Snapin/Pallidin Filament PF00038.21 RJW63315.1 - 0.094 12.3 4.8 0.24 10.9 4.3 1.8 1 1 0 1 1 1 0 Intermediate filament protein TMF_DNA_bd PF12329.8 RJW63315.1 - 0.96 9.5 5.2 1.2 9.2 1.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AATF-Che1 PF13339.6 RJW63315.1 - 1 10.0 6.0 0.25 12.0 1.7 2.1 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor ZapB PF06005.12 RJW63315.1 - 3.9 8.0 9.3 7.5 7.1 1.7 3.1 1 1 1 2 2 2 0 Cell division protein ZapB Golgin_A5 PF09787.9 RJW63315.1 - 9.2 5.6 11.7 0.12 11.8 3.6 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 HNF-1B_C PF04812.13 RJW63317.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus DAGAT PF03982.13 RJW63318.1 - 3.2e-75 252.8 0.0 2.8e-69 233.3 0.0 2.2 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Pkinase PF00069.25 RJW63319.1 - 1.6e-62 211.3 0.0 1.9e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63319.1 - 7.2e-28 97.6 0.0 9.9e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RJW63319.1 - 0.00012 21.5 0.5 0.00019 20.9 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW63319.1 - 0.00046 20.2 0.1 0.00089 19.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RJW63319.1 - 0.001 18.4 0.2 0.0022 17.4 0.2 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW63319.1 - 0.02 13.8 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Trimer_CC PF08954.11 RJW63319.1 - 0.029 13.9 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 Trimerisation motif GLEYA PF10528.9 RJW63320.1 - 0.048 14.1 0.1 1.4 9.4 0.1 2.2 1 1 1 2 2 2 0 GLEYA domain Hist_deacetyl PF00850.19 RJW63323.1 - 7.1e-64 216.2 0.0 9.7e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DAGAT PF03982.13 RJW63324.1 - 1e-81 274.1 0.4 2.9e-72 243.1 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase RVT_1 PF00078.27 RJW63325.1 - 3.1e-39 134.8 0.0 6.6e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) JAB PF01398.21 RJW63325.1 - 1.1e-12 48.0 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Exo_endo_phos PF03372.23 RJW63325.1 - 0.00022 20.8 0.2 0.0023 17.5 0.1 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF2656 PF10847.8 RJW63325.1 - 0.025 14.7 0.0 0.58 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) ASC PF00858.24 RJW63329.1 - 1.3e-67 228.8 1.1 1.6e-67 228.5 1.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF3797 PF12677.7 RJW63329.1 - 0.084 12.8 0.1 0.28 11.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) MFS_1 PF07690.16 RJW63330.1 - 1.9e-11 43.5 3.0 1.9e-11 43.5 3.0 2.1 2 1 0 3 3 3 1 Major Facilitator Superfamily tRNA-synt_His PF13393.6 RJW63332.1 - 1.5e-40 139.4 0.2 3.9e-35 121.6 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 RJW63332.1 - 2.3e-12 46.9 0.0 5.2e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 RJW63332.1 - 8.3e-05 22.2 0.3 0.00088 18.9 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.20 RJW63332.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Dicty_REP PF05086.12 RJW63332.1 - 1.7 6.5 4.1 2.7 5.9 4.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cation_ATPase_C PF00689.21 RJW63335.1 - 2.9e-45 154.2 5.5 5.8e-45 153.2 5.5 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RJW63335.1 - 9.5e-44 149.1 0.3 1.8e-43 148.2 0.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 RJW63335.1 - 5.2e-21 74.5 0.1 1e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RJW63335.1 - 4.4e-19 69.6 0.1 6.7e-18 65.7 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RJW63335.1 - 8.2e-07 29.0 2.3 8.4e-07 29.0 0.6 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RJW63335.1 - 4.8e-05 23.8 0.0 0.00031 21.2 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3738 PF12543.8 RJW63335.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) DUF5511 PF17630.2 RJW63337.1 - 0.014 15.6 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5511) TTR-52 PF01060.23 RJW63338.1 - 0.0012 19.5 0.9 0.52 11.0 0.2 2.3 2 0 0 2 2 2 2 Transthyretin-like family Med20 PF08612.11 RJW63338.1 - 0.0038 16.6 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ALMS_motif PF15309.6 RJW63338.1 - 0.057 13.9 2.5 0.091 13.2 2.5 1.3 1 0 0 1 1 1 0 ALMS motif MGC-24 PF05283.11 RJW63338.1 - 0.066 13.7 0.5 0.066 13.7 0.5 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Rhodanese_C PF12368.8 RJW63338.1 - 0.38 11.2 4.1 13 6.2 0.6 2.4 2 0 0 2 2 2 0 Rhodanase C-terminal TFB6 PF17110.5 RJW63339.1 - 0.18 11.6 13.0 0.034 13.9 1.3 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH SDA1 PF05285.12 RJW63339.1 - 0.61 9.5 15.0 0.73 9.2 15.0 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 RJW63339.1 - 0.66 8.2 12.9 0.66 8.2 12.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RJW63339.1 - 1.5 6.9 13.4 1.6 6.8 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 RJW63339.1 - 2.1 6.8 7.2 2.2 6.7 7.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDE_Tnp_IS1595 PF12762.7 RJW63342.1 - 0.00045 20.3 0.0 0.00048 20.2 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain UBA_e1_thiolCys PF10585.9 RJW63344.1 - 1.5e-55 188.9 0.0 2.9e-55 187.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 RJW63344.1 - 4.2e-53 180.2 0.7 5.9e-38 130.6 0.0 3.2 2 1 1 3 3 3 3 ThiF family E1_UFD PF09358.10 RJW63344.1 - 2.9e-08 34.3 0.0 6.6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain HEAT PF02985.22 RJW63346.1 - 0.0058 16.8 1.3 2.7 8.5 0.3 2.7 2 1 0 2 2 2 2 HEAT repeat Cnd1 PF12717.7 RJW63346.1 - 0.024 14.7 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 BTB PF00651.31 RJW63347.1 - 8.3e-32 109.7 0.3 1.4e-31 109.0 0.1 1.5 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 RJW63347.1 - 0.00035 20.7 0.1 0.011 15.8 0.1 2.2 2 0 0 2 2 2 1 MATH domain BACK PF07707.15 RJW63347.1 - 0.0038 17.3 0.1 0.17 12.0 0.0 2.8 2 1 1 3 3 3 1 BTB And C-terminal Kelch BTB_2 PF02214.22 RJW63347.1 - 0.044 14.1 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain ABC_membrane PF00664.23 RJW63348.1 - 2.4e-64 217.6 11.9 3.2e-64 217.2 11.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region tRNA-synt_1b PF00579.25 RJW63349.1 - 2.1e-49 168.4 0.0 2.9e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ABC_tran PF00005.27 RJW63350.1 - 2.8e-51 173.6 0.1 1.4e-36 126.1 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RJW63350.1 - 4.5e-40 138.0 8.8 6.7e-40 137.5 8.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RJW63350.1 - 5.6e-09 35.8 0.3 0.00021 20.8 0.0 3.7 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RJW63350.1 - 7.6e-09 35.7 0.1 0.0038 17.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RJW63350.1 - 1.2e-08 34.6 0.1 0.0038 16.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RJW63350.1 - 1.3e-08 35.4 1.6 0.018 15.4 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 RJW63350.1 - 4.1e-07 30.3 0.2 0.062 13.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 RJW63350.1 - 5.6e-07 29.6 0.0 0.024 14.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 RJW63350.1 - 1.8e-06 27.4 0.0 0.029 13.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.6 RJW63350.1 - 2.2e-06 27.7 0.1 0.15 11.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 RJW63350.1 - 1.1e-05 25.2 0.0 0.0071 16.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RJW63350.1 - 1.9e-05 24.3 0.0 0.07 12.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region G-alpha PF00503.20 RJW63350.1 - 2.6e-05 23.6 0.0 0.062 12.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_23 PF13476.6 RJW63350.1 - 0.00019 22.0 0.1 0.82 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 RJW63350.1 - 0.00023 21.2 0.0 0.98 9.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_5 PF07728.14 RJW63350.1 - 0.00036 20.6 0.3 0.75 9.8 0.0 3.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 RJW63350.1 - 0.00072 20.0 0.0 3.6 8.0 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 RJW63350.1 - 0.001 19.1 0.0 0.21 11.5 0.0 2.7 2 1 1 3 3 3 1 Rad17 P-loop domain NB-ARC PF00931.22 RJW63350.1 - 0.0012 18.1 0.0 0.95 8.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DUF815 PF05673.13 RJW63350.1 - 0.0023 17.1 0.0 1 8.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 RJW63350.1 - 0.0025 18.4 0.0 1.4 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 RJW63350.1 - 0.0034 16.2 0.1 0.0098 14.7 0.0 1.7 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 RJW63350.1 - 0.0035 17.0 0.1 1.1 8.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 RJW63350.1 - 0.0051 17.0 0.0 3 8.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RJW63350.1 - 0.0053 17.1 0.0 3.7 8.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.7 RJW63350.1 - 0.0057 15.6 0.0 1.8 7.4 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain APS_kinase PF01583.20 RJW63350.1 - 0.0098 15.8 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase Ploopntkinase3 PF18751.1 RJW63350.1 - 0.013 15.5 0.0 5 7.0 0.0 2.7 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 SbcCD_C PF13558.6 RJW63350.1 - 0.014 15.6 0.2 0.22 11.8 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 RJW63350.1 - 0.019 15.0 0.1 6.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain PRK PF00485.18 RJW63350.1 - 0.02 14.6 0.0 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 RJW63350.1 - 0.022 14.7 0.1 9.3 6.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 RJW63350.1 - 0.025 14.0 0.0 4.7 6.6 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein Roc PF08477.13 RJW63350.1 - 0.037 14.3 0.1 9.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 RJW63350.1 - 0.039 13.5 0.1 12 5.4 0.0 2.9 3 0 0 3 3 2 0 Ferrous iron transport protein B Viral_helicase1 PF01443.18 RJW63350.1 - 0.043 13.6 0.1 1.5 8.5 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.18 RJW63350.1 - 0.06 12.6 0.0 13 5.0 0.0 2.4 2 0 0 2 2 2 0 Septin TsaE PF02367.17 RJW63350.1 - 0.062 13.3 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF927 PF06048.11 RJW63350.1 - 0.063 12.8 0.2 8 5.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF927) AAA_17 PF13207.6 RJW63350.1 - 0.073 13.5 0.0 16 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RJW63350.1 - 0.092 12.5 0.2 14 5.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 RJW63350.1 - 0.1 12.5 0.3 23 4.9 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 RJW63350.1 - 0.13 12.5 0.0 21 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Asp PF00026.23 RJW63351.1 - 5.6e-52 177.1 0.0 6.3e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW63351.1 - 1.5e-07 31.8 0.0 0.0076 16.5 0.0 2.2 1 1 0 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RJW63351.1 - 0.0032 17.3 0.0 0.0087 15.9 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Ig_3 PF13927.6 RJW63354.1 - 1.8e-26 92.5 0.1 2.3e-11 44.1 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 RJW63354.1 - 2.1e-20 72.5 0.0 8.5e-11 41.8 0.0 3.9 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW63354.1 - 6.9e-17 61.6 0.1 3.5e-06 27.3 0.0 4.0 5 0 0 5 5 5 3 Immunoglobulin domain ig PF00047.25 RJW63354.1 - 9.6e-11 41.7 0.0 1.9e-05 24.7 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RJW63354.1 - 2.2e-06 27.8 0.4 0.027 14.7 0.1 4.4 3 2 1 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 RJW63354.1 - 1.2e-05 25.3 0.2 0.13 12.3 0.0 4.0 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain HA2 PF04408.23 RJW63355.1 - 1.3e-24 86.5 0.2 2.7e-24 85.5 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RJW63355.1 - 9.2e-12 45.3 0.0 1.9e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RJW63355.1 - 7.7e-08 32.3 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 RJW63355.1 - 0.00034 21.0 0.1 0.00077 19.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RJW63355.1 - 0.00066 19.3 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW63355.1 - 0.00074 19.8 0.2 0.0026 18.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RJW63355.1 - 0.0073 16.8 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 RJW63355.1 - 0.0086 15.7 0.1 0.022 14.4 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 RJW63355.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RJW63355.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 RJW63355.1 - 0.043 14.3 0.3 0.15 12.6 0.2 1.8 1 1 0 2 2 2 0 ABC transporter NACHT PF05729.12 RJW63355.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain HTH_IclR PF09339.10 RJW63355.1 - 0.069 13.0 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain AAA_7 PF12775.7 RJW63355.1 - 0.086 12.4 0.1 0.45 10.0 0.1 2.2 2 1 0 3 3 3 0 P-loop containing dynein motor region PhoH PF02562.16 RJW63355.1 - 0.15 11.5 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein WD40 PF00400.32 RJW63357.1 - 8.3e-48 159.4 38.7 2.3e-08 34.6 0.3 11.5 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 RJW63357.1 - 1.5e-34 118.9 5.6 4e-34 117.5 5.6 1.7 1 1 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 RJW63357.1 - 4.6e-07 30.0 4.6 1.7 9.0 0.1 6.5 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW63357.1 - 0.00025 20.1 2.7 0.072 12.0 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RJW63357.1 - 0.0029 16.3 5.4 0.51 8.9 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Pkinase PF00069.25 RJW63360.1 - 1.5e-42 145.8 0.0 2.5e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63360.1 - 1.4e-27 96.6 0.0 2.6e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW63360.1 - 0.00027 20.4 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RJW63360.1 - 0.0014 17.5 0.0 0.0024 16.7 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RJW63360.1 - 0.0095 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RJW63360.1 - 0.022 14.1 0.1 0.051 12.9 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.27 RJW63362.1 - 2.3e-11 43.7 0.0 3.3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BBIP10 PF14777.6 RJW63362.1 - 1e-06 28.2 0.5 1.7e-06 27.4 0.5 1.4 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 Ig_3 PF13927.6 RJW63363.1 - 1.5e-14 54.3 0.1 6.7e-09 36.2 0.1 2.9 2 1 1 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RJW63363.1 - 1.3e-11 44.6 0.2 2.3e-11 43.8 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 RJW63363.1 - 4.8e-10 39.5 0.0 9.6e-08 32.1 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RJW63363.1 - 4.4e-09 36.3 0.1 8.8e-07 28.9 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW63363.1 - 5.4e-07 29.9 0.1 0.0018 18.6 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 RJW63363.1 - 0.0013 18.7 0.0 0.0096 16.0 0.0 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RJW63363.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Lipin_N PF04571.14 RJW63364.1 - 3.2e-30 104.1 0.0 4.6e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 lipin, N-terminal conserved region Peptidase_C48 PF02902.19 RJW63365.1 - 1.3e-27 97.1 0.3 1.6e-21 77.2 0.1 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain AMP-binding PF00501.28 RJW63367.1 - 1.7e-79 267.4 0.0 2.2e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RJW63367.1 - 0.093 13.7 0.0 0.26 12.3 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF1011 PF06237.12 RJW63370.1 - 3.7e-14 52.8 10.2 2.2e-10 40.8 5.8 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1011) GIY-YIG PF01541.24 RJW63371.1 - 0.00018 21.7 0.2 0.00049 20.3 0.2 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF2034 PF10356.9 RJW63371.1 - 0.0042 16.5 1.7 0.43 10.0 0.2 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF2034) LNP1 PF15419.6 RJW63371.1 - 0.086 13.1 0.3 0.086 13.1 0.3 1.8 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 HECT PF00632.25 RJW63372.1 - 5.5e-86 288.8 0.0 8.9e-86 288.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 RJW63372.1 - 0.039 13.7 0.2 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Mac PF12464.8 RJW63373.1 - 0.044 14.0 0.5 7.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Maltose acetyltransferase Abhydrolase_6 PF12697.7 RJW63376.1 - 0.0011 19.6 0.4 0.0013 19.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RJW63376.1 - 0.0096 15.6 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RJW63376.1 - 0.16 11.2 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RRM_1 PF00076.22 RJW63378.1 - 1.5e-16 60.0 0.1 2.5e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW63378.1 - 0.00016 21.7 0.0 0.00041 20.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 RJW63378.1 - 0.0089 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RJW63378.1 - 0.16 12.0 0.1 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Profilin PF00235.19 RJW63379.1 - 2.2e-14 53.8 0.0 2.5e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Profilin Bep_C_terminal PF17841.1 RJW63379.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.6 1 1 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) Pkinase PF00069.25 RJW63380.1 - 2.5e-64 217.2 0.0 3.4e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63380.1 - 1.5e-37 129.3 0.0 2.1e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 RJW63380.1 - 2.9e-26 91.7 0.0 5.6e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 RJW63380.1 - 1.7e-22 79.1 32.3 4.3e-13 48.9 15.6 3.6 4 0 0 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 RJW63380.1 - 3.1e-07 31.0 1.3 8.1e-07 29.7 1.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 RJW63380.1 - 0.0026 17.2 0.0 0.085 12.2 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 RJW63380.1 - 0.079 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 RJW63380.1 - 0.15 11.6 0.1 0.99 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 RJW63380.1 - 0.17 10.8 0.1 0.63 8.9 0.0 1.6 1 1 0 2 2 2 0 Haspin like kinase domain ParA PF10609.9 RJW63381.1 - 4.6e-79 265.3 0.0 8.3e-79 264.5 0.0 1.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RJW63381.1 - 2.9e-06 27.4 0.0 0.0015 18.6 0.3 2.8 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 RJW63381.1 - 3.2e-05 23.9 0.0 7.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RJW63381.1 - 5e-05 23.7 0.1 0.0019 18.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_31 PF13614.6 RJW63381.1 - 6.3e-05 23.0 0.2 0.00081 19.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 RJW63381.1 - 0.0016 18.3 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 RJW63381.1 - 0.0042 16.3 0.2 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase TF_Zn_Ribbon PF08271.12 RJW63381.1 - 0.018 14.6 0.2 0.039 13.5 0.2 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding IstB_IS21 PF01695.17 RJW63381.1 - 0.028 14.2 0.1 0.085 12.6 0.0 1.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 RJW63381.1 - 0.035 13.7 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 RJW63381.1 - 0.1 11.8 0.1 7.6 5.7 0.0 2.2 2 0 0 2 2 2 0 ATPase MipZ DBC1 PF14443.6 RJW63383.1 - 3.4e-45 153.1 0.0 7.4e-45 152.0 0.0 1.5 1 0 0 1 1 1 1 DBC1 SAP PF02037.27 RJW63383.1 - 1.3e-09 37.6 0.3 2.8e-09 36.5 0.3 1.6 1 0 0 1 1 1 1 SAP domain EF-hand_6 PF13405.6 RJW63383.1 - 0.021 14.7 0.1 0.07 13.1 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 RJW63383.1 - 0.092 13.2 1.2 0.25 11.8 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair DUF1456 PF07308.13 RJW63383.1 - 0.11 12.8 0.0 0.43 11.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) Prominin PF05478.11 RJW63383.1 - 8.4 4.2 5.3 1.3 6.9 1.2 1.6 2 0 0 2 2 2 0 Prominin MULE PF10551.9 RJW63384.1 - 8.9e-12 45.3 0.3 5.5e-10 39.5 0.1 2.5 2 0 0 2 2 2 2 MULE transposase domain SecG PF03840.14 RJW63385.1 - 0.096 12.8 0.5 0.096 12.8 0.5 2.1 2 0 0 2 2 2 0 Preprotein translocase SecG subunit DIL PF01843.19 RJW63385.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 DIL domain RVT_1 PF00078.27 RJW63386.1 - 3.7e-06 26.6 0.0 1.1e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAAD PF18752.1 RJW63386.1 - 0.022 14.6 0.3 0.022 14.6 0.3 2.1 2 1 1 3 3 3 0 Dictyosteliid AID/APOBEC-like Deaminase Ldh_1_N PF00056.23 RJW63387.1 - 7.7e-43 146.0 0.7 1.3e-42 145.3 0.7 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 RJW63387.1 - 1.2e-22 80.6 0.0 2.2e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 RJW63387.1 - 9.1e-05 22.1 0.9 0.00017 21.3 0.9 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Poly_export PF02563.16 RJW63387.1 - 0.031 14.5 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein Glyco_hydro_4 PF02056.16 RJW63387.1 - 0.038 13.5 2.6 0.07 12.7 0.2 2.1 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase AlaDh_PNT_C PF01262.21 RJW63387.1 - 0.044 13.1 0.1 0.066 12.5 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain fn3_4 PF16794.5 RJW63393.1 - 1.2e-28 99.0 0.1 2.1e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Fibronectin-III type domain NAD_Gly3P_dh_C PF07479.14 RJW63394.1 - 5.2e-35 120.8 0.0 6.9e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 RJW63394.1 - 3.3e-05 23.9 0.0 5.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DIX PF00778.17 RJW63395.1 - 2.6e-24 84.8 0.0 9e-24 83.1 0.0 1.9 1 1 0 1 1 1 1 DIX domain RGS PF00615.19 RJW63395.1 - 3.2e-20 72.6 0.0 6.3e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.10 RJW63395.1 - 5.3e-05 23.2 0.5 5.3e-05 23.2 0.5 2.6 2 0 0 2 2 2 1 Axin beta-catenin binding domain SUI1 PF01253.22 RJW63396.1 - 4.4e-16 59.2 0.0 9.1e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.18 RJW63396.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain zf-Di19 PF05605.12 RJW63397.1 - 1.1e-05 25.6 0.5 2.4e-05 24.5 0.5 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 RJW63397.1 - 0.0046 17.7 3.1 0.16 12.9 0.2 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.15 RJW63397.1 - 0.044 13.8 1.9 0.24 11.4 0.3 2.8 3 0 0 3 3 3 0 BED zinc finger PHD_Oberon PF07227.11 RJW63397.1 - 0.062 13.2 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 PHD - plant homeodomain finger protein DUF2491 PF10679.9 RJW63397.1 - 0.15 11.2 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) zf-AD PF07776.15 RJW63397.1 - 0.17 12.1 3.3 6 7.2 0.4 2.8 2 1 0 3 3 3 0 Zinc-finger associated domain (zf-AD) zf-met PF12874.7 RJW63397.1 - 0.29 11.6 0.1 0.29 11.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-CCHC_2 PF13696.6 RJW63397.1 - 1.7 8.5 6.3 9.5 6.2 0.8 2.4 2 0 0 2 2 2 0 Zinc knuckle Peptidase_C2 PF00648.21 RJW63399.1 - 1.5e-09 37.4 0.2 4.6e-08 32.4 0.0 2.8 2 1 1 3 3 3 1 Calpain family cysteine protease IQ PF00612.27 RJW63399.1 - 0.66 9.9 7.2 0.071 12.9 0.8 2.7 3 0 0 3 3 3 0 IQ calmodulin-binding motif Me-amine-dh_H PF06433.11 RJW63400.1 - 0.22 10.4 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) NAD_Gly3P_dh_N PF01210.23 RJW63401.1 - 8.8e-22 77.8 0.0 1e-21 77.5 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 RJW63401.1 - 0.015 15.9 0.0 0.044 14.4 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ribos_L4_asso_C PF14374.6 RJW63401.1 - 0.18 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain MFS_1 PF07690.16 RJW63402.1 - 1.6e-37 129.3 34.4 2.6e-23 82.5 15.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RJW63402.1 - 9.2e-06 25.2 25.5 0.00084 18.7 11.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB FANC_SAP PF18081.1 RJW63402.1 - 0.033 14.3 0.2 0.1 12.8 0.2 1.9 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain DUF4381 PF14316.6 RJW63402.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) TIMELESS PF04821.14 RJW63403.1 - 2.6e-55 187.7 1.7 5.5e-55 186.6 0.2 2.1 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 RJW63403.1 - 9.6e-20 71.2 1.1 9.6e-20 71.2 1.1 2.6 3 0 0 3 3 3 1 Timeless protein C terminal region Ldh_1_N PF00056.23 RJW63404.1 - 8.8e-42 142.5 0.1 1.2e-41 142.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 RJW63404.1 - 5.4e-21 75.2 0.0 8.8e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 RJW63404.1 - 0.00092 18.8 0.8 0.0023 17.6 0.8 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 RJW63404.1 - 0.0032 17.0 0.0 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase AlaDh_PNT_C PF01262.21 RJW63404.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_4C PF11975.8 RJW63404.1 - 0.033 14.3 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain RVT_1 PF00078.27 RJW63405.1 - 1.7e-09 37.6 0.1 1.9e-09 37.4 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAA_hydrolase_N PF09298.11 RJW63405.1 - 0.12 12.6 0.0 0.15 12.2 0.0 1.3 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal Rieske PF00355.26 RJW63407.1 - 1.9e-10 40.6 1.0 2.9e-10 39.9 1.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 RJW63407.1 - 0.0028 18.1 0.9 0.0047 17.4 0.9 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Hepatitis_core PF00906.20 RJW63408.1 - 0.13 11.9 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Hepatitis core antigen LCAT PF02450.15 RJW63409.1 - 3.9e-47 161.3 0.0 4.4e-40 138.1 0.0 2.0 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 RJW63409.1 - 1.6e-06 28.9 0.0 3.1e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RJW63409.1 - 0.019 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RJW63409.1 - 0.05 13.2 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 RJW63409.1 - 0.053 13.2 0.3 0.2 11.4 0.0 2.0 3 0 0 3 3 3 0 PGAP1-like protein GCV_H PF01597.19 RJW63410.1 - 1.4e-41 141.2 0.3 1.9e-41 140.8 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 RJW63410.1 - 0.00016 21.5 0.1 0.00042 20.1 0.0 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Aldo_ket_red PF00248.21 RJW63410.1 - 0.074 12.2 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Aldo/keto reductase family ADK PF00406.22 RJW63411.1 - 3e-12 46.9 0.0 2.5e-08 34.2 0.0 3.7 1 1 0 1 1 1 1 Adenylate kinase CH_2 PF06294.11 RJW63411.1 - 3.7e-10 39.8 0.0 2.1e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 CH-like domain in sperm protein RVT_1 PF00078.27 RJW63411.1 - 1.9e-07 30.8 0.0 4.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_17 PF13207.6 RJW63411.1 - 8.5e-07 29.5 0.0 8.5e-07 29.5 0.0 4.1 2 2 1 3 3 3 1 AAA domain AAA_18 PF13238.6 RJW63411.1 - 0.00029 21.4 0.0 0.00029 21.4 0.0 3.4 2 1 2 4 4 4 1 AAA domain Hydin_ADK PF17213.3 RJW63411.1 - 0.079 13.2 0.1 0.079 13.2 0.1 4.3 3 1 2 5 5 5 0 Hydin Adenylate kinase-like domain Ribosomal_L19 PF01245.20 RJW63412.1 - 1.7e-13 50.4 0.0 2.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 STOP PF05217.12 RJW63414.1 - 0.44 10.9 17.7 3.1e+02 1.8 0.0 10.9 15 0 0 15 15 15 0 STOP protein Ldh_1_N PF00056.23 RJW63416.1 - 6.8e-44 149.4 0.3 1e-43 148.8 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 RJW63416.1 - 2e-22 79.9 0.0 6.4e-22 78.2 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain AlaDh_PNT_C PF01262.21 RJW63416.1 - 0.0011 18.3 0.7 0.0018 17.6 0.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 RJW63416.1 - 0.036 13.6 3.0 0.13 11.8 3.0 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 RJW63416.1 - 0.053 13.1 2.7 0.39 10.3 0.2 2.6 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase LCAT PF02450.15 RJW63418.1 - 2.6e-45 155.3 0.0 3.8e-38 131.7 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 RJW63418.1 - 5.8e-05 23.8 0.1 0.00017 22.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RJW63418.1 - 0.0023 17.2 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 RJW63418.1 - 0.019 14.7 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_S9 PF00326.21 RJW63418.1 - 0.091 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family 2OG-FeII_Oxy_4 PF13661.6 RJW63419.1 - 0.044 14.4 0.0 0.087 13.5 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PI3Ka PF00613.20 RJW63420.1 - 2.7e-38 131.2 0.4 9.6e-38 129.4 0.6 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 RJW63420.1 - 4.8e-27 95.4 0.1 1.2e-23 84.2 0.1 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 RJW63420.1 - 2.9e-06 26.9 0.0 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PI3K_C2 PF00792.24 RJW63420.1 - 4.6e-06 26.6 0.0 9.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Sec63 PF02889.16 RJW63421.1 - 4.1e-07 29.4 0.0 3.5e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain Pkinase PF00069.25 RJW63423.1 - 1e-44 152.9 0.2 1.4e-44 152.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63423.1 - 2.4e-24 86.0 0.1 2.9e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW63423.1 - 0.0042 16.4 0.0 0.006 15.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW63423.1 - 0.053 12.5 0.1 0.14 11.0 0.0 1.5 1 1 1 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 RJW63423.1 - 0.068 12.2 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 BCL_N PF04714.13 RJW63426.1 - 6.7e-25 86.9 4.6 1.2e-24 86.1 4.6 1.5 1 0 0 1 1 1 1 BCL7, N-terminal conserver region GRIM-19 PF06212.12 RJW63427.1 - 1e-48 164.6 0.4 1.2e-48 164.5 0.4 1.0 1 0 0 1 1 1 1 GRIM-19 protein ubiquitin PF00240.23 RJW63428.1 - 3e-05 23.7 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Tugs PF17840.1 RJW63428.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain AAA_16 PF13191.6 RJW63429.1 - 0.00031 21.2 0.0 0.0031 17.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 RJW63429.1 - 0.00058 19.8 0.0 0.0029 17.6 0.0 2.2 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 RJW63429.1 - 0.00091 19.8 0.0 0.0026 18.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 RJW63429.1 - 0.002 18.4 0.0 0.0057 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_17 PF13431.6 RJW63429.1 - 0.0036 17.6 2.0 1.5 9.4 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat ABC_membrane_2 PF06472.15 RJW63429.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ATPase_2 PF01637.18 RJW63429.1 - 0.031 14.2 0.0 0.094 12.6 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 RJW63429.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 RJW63429.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RJW63429.1 - 0.12 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 RJW63429.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RJW63429.1 - 0.16 11.9 0.0 0.92 9.4 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase TPR_11 PF13414.6 RJW63429.1 - 0.16 11.6 1.1 0.85 9.3 0.0 2.9 4 0 0 4 4 4 0 TPR repeat TPR_9 PF13371.6 RJW63429.1 - 1 9.5 5.3 2.3 8.4 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPH PF13868.6 RJW63430.1 - 5.6e-13 48.1 125.0 5.6e-13 48.1 125.0 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Ribosomal_S5 PF00333.20 RJW63431.1 - 3e-27 94.4 0.7 5.9e-27 93.4 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 RJW63431.1 - 5.2e-25 86.7 0.0 8.8e-25 86.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 RJW63431.1 - 2.2 8.9 9.7 4.7 7.8 9.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Sdh5 PF03937.16 RJW63432.1 - 3.9e-19 68.4 0.0 9.8e-19 67.1 0.0 1.6 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Pyridoxal_deC PF00282.19 RJW63433.1 - 4e-116 387.8 0.0 4.8e-116 387.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 RJW63433.1 - 0.00034 19.4 0.0 0.00051 18.8 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 RJW63433.1 - 0.0019 17.5 0.0 0.0026 17.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 RJW63433.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.19 RJW63433.1 - 0.24 10.3 0.0 0.97 8.3 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V Apt1 PF10351.9 RJW63434.1 - 1.4 7.7 5.9 2.3 7.0 5.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribonuc_red_lgC PF02867.15 RJW63435.1 - 1e-189 631.5 0.0 1.3e-189 631.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 RJW63435.1 - 1.3e-20 73.2 0.0 2.7e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 RJW63435.1 - 1.2e-13 51.4 0.0 3.9e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain DIRP PF06584.13 RJW63437.1 - 4.3e-21 75.1 0.5 1.4e-20 73.4 0.1 2.1 2 0 0 2 2 2 1 DIRP Lipocalin_3 PF12702.7 RJW63438.1 - 0.0061 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Lipocalin-like PH PF00169.29 RJW63439.1 - 8.6e-15 55.1 0.5 1.6e-14 54.3 0.5 1.5 1 0 0 1 1 1 1 PH domain DUF956 PF06115.11 RJW63439.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF956) Glyco_transf_21 PF13506.6 RJW63445.1 - 5.1e-32 110.7 0.0 6.5e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 RJW63445.1 - 6.3e-13 49.1 0.0 8.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 RJW63445.1 - 5.2e-12 46.1 2.6 9.8e-12 45.2 2.6 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 RUN PF02759.19 RJW63448.1 - 2.9e-25 88.8 0.0 6.3e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 RUN domain Ras PF00071.22 RJW63449.1 - 4.1e-54 182.6 0.0 4.8e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW63449.1 - 6e-31 107.2 0.0 8.1e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW63449.1 - 1.7e-17 63.4 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW63449.1 - 7.5e-06 25.6 0.3 6.2e-05 22.6 0.1 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RJW63449.1 - 7.4e-05 22.2 0.0 9.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RJW63449.1 - 0.00085 19.4 0.0 0.0017 18.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 RJW63449.1 - 0.0036 17.6 0.3 0.028 14.7 0.3 2.1 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 RJW63449.1 - 0.0096 15.7 0.3 0.73 9.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 RJW63449.1 - 0.016 15.5 0.1 0.035 14.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 RJW63449.1 - 0.032 13.7 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 RJW63449.1 - 0.044 13.4 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 RJW63449.1 - 0.057 13.1 0.1 0.13 11.9 0.1 1.6 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 RJW63449.1 - 0.083 13.1 0.2 0.65 10.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain TetR_C_16 PF17920.1 RJW63449.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ets PF00178.22 RJW63450.1 - 1.3e-31 108.9 2.9 2.6e-31 107.9 2.9 1.5 1 0 0 1 1 1 1 Ets-domain Mg_trans_NIPA PF05653.14 RJW63452.1 - 2.7e-98 328.7 20.2 3.4e-98 328.4 20.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 RJW63452.1 - 0.00014 22.0 5.0 0.00014 22.0 5.0 3.3 2 1 1 3 3 3 1 EamA-like transporter family Chromosome_seg PF13889.6 RJW63454.1 - 5e-19 68.2 1.9 9.9e-19 67.3 1.9 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 RJW63454.1 - 5.4e-13 49.3 0.2 6.1e-12 45.9 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4210) Pkinase PF00069.25 RJW63455.1 - 1.4e-58 198.4 0.0 2.4e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63455.1 - 1e-31 110.1 0.0 1.9e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Phage_HK97_TLTM PF06120.11 RJW63455.1 - 0.0024 17.1 1.2 0.004 16.4 1.2 1.2 1 0 0 1 1 1 1 Tail length tape measure protein Kinase-like PF14531.6 RJW63455.1 - 0.023 14.0 0.0 0.094 12.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pet100 PF09803.9 RJW63455.1 - 5.7 7.5 6.5 8.4 7.0 0.4 3.1 3 0 0 3 3 3 0 Pet100 U3_assoc_6 PF08640.11 RJW63457.1 - 2.7e-17 62.6 10.3 2.7e-17 62.6 10.3 2.6 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 Uso1_p115_C PF04871.13 RJW63457.1 - 0.022 15.1 2.7 0.022 15.1 2.7 3.2 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_14 PF13428.6 RJW63457.1 - 0.077 13.9 0.5 6.5 7.9 0.3 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Allexi_40kDa PF05549.11 RJW63457.1 - 3.6 7.0 9.3 1.2 8.6 3.0 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein Prominin PF05478.11 RJW63457.1 - 6.5 4.6 9.5 0.67 7.8 2.3 2.2 2 0 0 2 2 2 0 Prominin YebO PF13974.6 RJW63457.1 - 8.9 6.5 8.3 0.44 10.6 1.5 2.3 2 0 0 2 2 2 0 YebO-like protein Pro_isomerase PF00160.21 RJW63458.1 - 2.2e-49 167.8 0.0 6.4e-49 166.3 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_C14 PF00656.22 RJW63458.1 - 1.3e-06 28.6 0.1 4.1e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 Caspase domain I-set PF07679.16 RJW63458.1 - 5.7e-06 26.3 0.0 1.7e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Rtf2 PF04641.12 RJW63458.1 - 7.8e-05 22.2 0.2 0.00021 20.7 0.2 1.7 1 0 0 1 1 1 1 Rtf2 RING-finger Ig_3 PF13927.6 RJW63458.1 - 0.00015 22.3 0.3 0.00083 19.9 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Ago_PAZ PF18309.1 RJW63458.1 - 0.019 15.6 0.2 3.9 8.2 0.1 2.7 2 0 0 2 2 2 0 Argonaute PAZ domain Rhomboid PF01694.22 RJW63459.1 - 1.1e-16 61.1 11.1 1.1e-11 45.0 2.2 3.0 3 0 0 3 3 3 2 Rhomboid family Ig_3 PF13927.6 RJW63460.1 - 2.9e-16 59.8 5.5 2.5e-05 24.8 0.2 5.2 3 2 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RJW63460.1 - 5.6e-12 45.6 0.0 0.0042 17.1 0.0 4.5 4 1 0 4 4 4 2 Immunoglobulin I-set domain ig PF00047.25 RJW63460.1 - 1.8e-11 44.0 1.4 0.00034 20.7 0.0 5.1 3 3 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RJW63460.1 - 2.8e-11 43.6 0.6 0.024 14.8 0.0 5.7 6 0 0 6 6 6 4 Immunoglobulin V-set domain Ig_2 PF13895.6 RJW63460.1 - 9e-09 35.6 0.2 0.00057 20.2 0.0 4.4 5 0 0 5 5 5 1 Immunoglobulin domain Izumo-Ig PF16706.5 RJW63460.1 - 0.0011 19.0 0.0 2.3 8.3 0.0 3.8 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RJW63460.1 - 0.0012 18.3 0.0 2.6 7.7 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain DUF4448 PF14610.6 RJW63460.1 - 0.0022 17.8 0.1 0.0038 17.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Ig_5 PF16681.5 RJW63460.1 - 0.0048 17.3 0.0 1.4 9.4 0.0 3.6 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RJW63460.1 - 0.012 15.9 0.0 0.12 12.6 0.0 2.7 5 0 0 5 5 5 0 T-cell surface glycoprotein CD3 delta chain ADIP PF11559.8 RJW63461.1 - 0.032 14.3 2.0 0.043 13.9 2.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2721 PF11026.8 RJW63461.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RVT_1 PF00078.27 RJW63464.1 - 2.7e-45 154.6 0.0 4.8e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW63464.1 - 0.00011 21.8 0.6 0.00025 20.7 0.6 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA PF00004.29 RJW63467.1 - 4.6e-43 146.8 0.0 8.9e-43 145.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW63467.1 - 5.4e-13 48.5 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 RJW63467.1 - 5.4e-07 29.9 0.0 1.3e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RJW63467.1 - 1.2e-06 28.6 0.0 4.3e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RJW63467.1 - 1.3e-06 28.9 0.5 7e-05 23.3 0.1 3.0 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 RJW63467.1 - 5.3e-06 26.3 0.1 1.4e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 RJW63467.1 - 5.5e-05 23.5 2.7 0.0099 16.1 0.5 3.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RJW63467.1 - 9.9e-05 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RJW63467.1 - 0.0017 18.5 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RJW63467.1 - 0.002 17.4 0.0 0.0049 16.1 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 RJW63467.1 - 0.0021 18.6 0.1 0.009 16.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RJW63467.1 - 0.0023 17.7 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 RJW63467.1 - 0.0075 15.7 0.1 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 RJW63467.1 - 0.0076 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 RJW63467.1 - 0.0082 15.5 0.0 0.026 13.9 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_3 PF07726.11 RJW63467.1 - 0.0097 15.8 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RJW63467.1 - 0.016 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 RJW63467.1 - 0.027 14.2 0.1 0.12 12.1 0.0 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 RJW63467.1 - 0.034 13.9 0.0 0.068 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 RJW63467.1 - 0.035 14.1 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RJW63467.1 - 0.035 13.3 0.1 0.094 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 RJW63467.1 - 0.037 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 RJW63467.1 - 0.045 13.5 0.5 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RJW63467.1 - 0.05 13.6 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain OmpH PF03938.14 RJW63467.1 - 0.05 13.9 3.1 0.1 12.9 3.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RNA_helicase PF00910.22 RJW63467.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 RJW63467.1 - 0.057 13.0 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RILP PF11461.8 RJW63467.1 - 0.058 13.6 4.2 0.15 12.3 4.2 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein Parvo_NS1 PF01057.17 RJW63467.1 - 0.062 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 FapA PF03961.13 RJW63467.1 - 0.068 11.8 2.5 0.1 11.2 2.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_30 PF13604.6 RJW63467.1 - 0.098 12.4 0.1 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RJW63467.1 - 0.11 12.9 1.3 0.34 11.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RJW63467.1 - 0.12 11.6 0.0 0.3 10.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 RJW63467.1 - 0.14 12.7 0.1 1.1 9.8 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Ion_trans_2 PF07885.16 RJW63468.1 - 6.4e-36 122.2 15.0 1.4e-18 66.6 3.4 2.5 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 RJW63468.1 - 4.5e-05 22.8 4.9 0.014 14.6 0.6 2.4 1 1 1 2 2 2 2 Ion transport protein DEAD PF00270.29 RJW63469.1 - 2.1e-22 79.7 0.0 5.2e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW63469.1 - 1.7e-10 41.2 0.1 5.6e-09 36.3 0.1 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW63469.1 - 2.1e-09 37.6 0.0 3.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sec63 PF02889.16 RJW63469.1 - 5.8e-09 35.5 0.0 9.4e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain RVT_1 PF00078.27 RJW63469.1 - 0.00075 19.1 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1160 PF06648.11 RJW63469.1 - 0.068 13.2 0.1 1.4 8.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1160) AAA_22 PF13401.6 RJW63469.1 - 0.14 12.4 0.1 0.65 10.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain Prenyltrans PF00432.21 RJW63472.1 - 7e-19 67.3 7.9 1.1e-07 31.5 0.1 5.4 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat DUF3902 PF13042.6 RJW63472.1 - 0.08 12.5 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) Tim44 PF04280.15 RJW63475.1 - 5.4e-35 120.7 0.1 6.1e-33 114.0 0.0 3.2 2 1 0 2 2 2 1 Tim44-like domain PPDK_N PF01326.19 RJW63475.1 - 0.046 13.0 0.2 0.07 12.4 0.2 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF4085 PF13315.6 RJW63475.1 - 0.073 12.7 2.4 0.11 12.1 0.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4085) DUF2267 PF10025.9 RJW63475.1 - 0.087 13.1 0.4 0.25 11.6 0.4 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Prominin PF05478.11 RJW63475.1 - 0.15 10.0 1.5 0.23 9.4 1.5 1.2 1 0 0 1 1 1 0 Prominin EMC3_TMCO1 PF01956.16 RJW63475.1 - 0.48 10.1 3.0 0.77 9.5 2.2 1.7 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF1690 PF07956.11 RJW63475.1 - 0.71 10.3 8.5 1.4 9.3 8.5 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Laminin_II PF06009.12 RJW63475.1 - 0.75 9.8 6.9 2.1 8.4 6.9 1.9 1 0 0 1 1 1 0 Laminin Domain II DUF3347 PF11827.8 RJW63475.1 - 6.7 6.8 6.8 8.8 6.5 1.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3347) ASFV_J13L PF05568.11 RJW63476.1 - 0.061 13.1 1.1 0.27 11.0 0.3 2.0 1 1 1 2 2 2 0 African swine fever virus J13L protein Got1 PF04178.12 RJW63477.1 - 3.6e-26 91.8 12.3 6e-26 91.1 12.3 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family CUB PF00431.20 RJW63478.1 - 1.4e-34 118.8 0.0 6.4e-17 61.9 0.0 2.1 2 0 0 2 2 2 2 CUB domain UPF0542 PF15086.6 RJW63480.1 - 2.1e-36 123.7 2.0 2.4e-36 123.5 2.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 DUF2206 PF09971.9 RJW63480.1 - 0.16 10.7 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Toxin_TOLIP PF00087.21 RJW63481.1 - 0.015 15.6 5.2 0.024 14.9 5.2 1.4 1 1 0 1 1 1 0 Snake toxin and toxin-like protein Kinesin PF00225.23 RJW63482.1 - 2.1e-42 145.2 6.4 2.9e-42 144.8 6.4 1.2 1 0 0 1 1 1 1 Kinesin motor domain FAM76 PF16046.5 RJW63482.1 - 0.00074 19.0 0.2 0.0014 18.1 0.2 1.3 1 0 0 1 1 1 1 FAM76 protein MMR_HSR1 PF01926.23 RJW63484.1 - 5.4e-10 39.4 0.0 2.9e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 RJW63484.1 - 0.0017 18.2 0.0 7.1 6.3 0.0 3.1 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 RJW63484.1 - 0.02 14.4 0.2 0.19 11.3 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B IIGP PF05049.13 RJW63484.1 - 0.027 13.5 0.2 0.044 12.9 0.2 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 RJW63484.1 - 0.036 14.0 0.6 6.8 6.6 0.1 2.7 1 1 1 2 2 2 0 RsgA GTPase cobW PF02492.19 RJW63484.1 - 0.18 11.4 0.0 3.7 7.1 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Aldedh PF00171.22 RJW63485.1 - 8.9e-154 512.4 0.0 1.2e-153 511.9 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAP3 PF10236.9 RJW63485.1 - 3.9e-44 151.1 0.0 6.5e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 DUF1487 PF07368.11 RJW63485.1 - 0.02 14.3 0.0 0.99 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF3314 PF11771.8 RJW63487.1 - 0.097 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) PAN_4 PF14295.6 RJW63488.1 - 4.1 7.4 16.2 5.9 6.9 1.7 4.3 4 1 0 4 4 4 0 PAN domain Sas10_Utp3 PF04000.15 RJW63489.1 - 0.044 14.4 0.0 0.07 13.8 0.0 1.3 1 0 0 1 1 1 0 Sas10/Utp3/C1D family PAN_1 PF00024.26 RJW63490.1 - 0.01 15.8 0.6 0.01 15.8 0.6 1.9 2 0 0 2 2 2 0 PAN domain PAN_4 PF14295.6 RJW63490.1 - 2.2 8.2 8.9 0.41 10.6 2.5 2.7 3 0 0 3 3 3 0 PAN domain Tudor_FRX1 PF18336.1 RJW63491.1 - 0.098 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain Actin PF00022.19 RJW63492.1 - 3.6e-152 506.7 0.0 1.2e-151 505.0 0.0 1.6 1 1 0 1 1 1 1 Actin Laminin_G_2 PF02210.24 RJW63493.1 - 2.2e-26 92.9 0.0 1.3e-10 41.9 0.0 3.6 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 RJW63493.1 - 1.9e-21 76.6 0.0 2.9e-07 30.7 0.1 4.5 3 1 0 3 3 3 3 Laminin G domain Laminin_EGF PF00053.24 RJW63493.1 - 1.9e-14 53.5 36.2 1.4e-08 34.8 14.4 5.2 5 0 0 5 5 5 3 Laminin EGF domain Kazal_2 PF07648.15 RJW63493.1 - 2.9e-07 30.5 2.0 2.9e-07 30.5 2.0 2.7 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EGF PF00008.27 RJW63493.1 - 3.3e-05 24.1 7.3 3.3e-05 24.1 7.3 6.1 6 1 0 6 6 6 1 EGF-like domain hEGF PF12661.7 RJW63493.1 - 0.00012 22.5 7.0 0.00012 22.5 7.0 6.5 7 0 0 7 7 7 1 Human growth factor-like EGF EGF_2 PF07974.13 RJW63493.1 - 0.0063 16.8 10.7 0.0063 16.8 10.7 6.3 6 2 1 7 7 7 1 EGF-like domain zf-C4 PF00105.18 RJW63494.1 - 1.1e-28 99.5 19.4 2.2e-28 98.5 19.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW63494.1 - 2.5e-10 40.3 0.0 4.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor STAT_int PF02865.17 RJW63497.1 - 0.011 16.1 0.1 0.018 15.5 0.1 1.4 1 1 0 1 1 1 0 STAT protein, protein interaction domain F-box_4 PF15966.5 RJW63497.1 - 0.024 14.5 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 F-box CNOT1_HEAT PF16418.5 RJW63497.1 - 0.037 14.1 0.2 0.051 13.6 0.2 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat FAA_hydrolase_N PF09298.11 RJW63497.1 - 0.11 12.7 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal NAP PF00956.18 RJW63498.1 - 1e-35 123.2 23.2 8.3e-31 107.1 15.1 3.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) NOA36 PF06524.12 RJW63498.1 - 0.12 11.7 6.3 0.2 11.0 6.3 1.4 1 0 0 1 1 1 0 NOA36 protein Sec20 PF03908.13 RJW63498.1 - 0.16 11.9 0.1 0.67 9.9 0.0 1.8 2 0 0 2 2 2 0 Sec20 MYT1 PF08474.11 RJW63498.1 - 0.39 10.6 3.3 0.6 10.0 3.3 1.4 1 0 0 1 1 1 0 Myelin transcription factor 1 Astro_capsid_p PF12226.8 RJW63498.1 - 6.9 5.7 8.4 11 5.1 8.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ASC PF00858.24 RJW63500.1 - 8e-06 25.1 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel PAN_1 PF00024.26 RJW63501.1 - 0.00012 21.9 0.8 0.00027 20.8 0.8 1.5 1 0 0 1 1 1 1 PAN domain ASC PF00858.24 RJW63502.1 - 8.7e-17 61.2 2.2 1.2e-16 60.7 2.2 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel fn3 PF00041.21 RJW63503.1 - 2.3e-14 53.5 4.9 5.7e-09 36.2 0.2 4.9 4 1 0 4 4 4 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW63503.1 - 0.0022 18.5 0.0 0.25 11.9 0.0 3.3 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RJW63503.1 - 0.061 13.7 0.0 13 6.3 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 RJW63503.1 - 0.1 12.5 0.2 2 8.4 0.0 2.7 3 0 0 3 3 3 0 Fibronectin-III type domain RNase_PH PF01138.21 RJW63505.1 - 1e-16 61.7 0.3 1.9e-16 60.8 0.3 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SCHIP-1 PF10148.9 RJW63506.1 - 5.5e-13 49.1 4.8 5.5e-13 49.1 4.8 2.2 2 1 0 2 2 2 1 Schwannomin-interacting protein 1 FEZ PF07763.13 RJW63506.1 - 0.008 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 FEZ-like protein zf-RING_4 PF14570.6 RJW63508.1 - 0.052 13.3 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DNA_pol_B PF00136.21 RJW63509.1 - 1.2e-108 363.8 0.0 1.7e-108 363.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 RJW63509.1 - 8.9e-27 94.1 0.0 2e-26 92.9 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 RJW63509.1 - 2.3e-18 66.6 0.0 5.9e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 RJW63509.1 - 1.1e-16 60.6 6.7 2.4e-16 59.6 6.7 1.6 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 RJW63509.1 - 0.0021 17.0 0.0 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Endonuclease_5 PF04493.14 RJW63510.1 - 5.5e-52 176.3 0.0 7e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 RJW63510.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 Actin PF00022.19 RJW63511.1 - 7.2e-151 502.4 0.0 2.3e-150 500.7 0.0 1.6 1 1 0 1 1 1 1 Actin PAN_1 PF00024.26 RJW63512.1 - 0.0015 18.5 2.7 0.0027 17.6 2.7 1.4 1 0 0 1 1 1 1 PAN domain RGS PF00615.19 RJW63513.1 - 1.9e-32 112.0 2.2 3.6e-32 111.1 2.2 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Actin PF00022.19 RJW63514.1 - 2.8e-145 484.0 0.0 9.2e-145 482.3 0.0 1.7 1 1 0 1 1 1 1 Actin Kazal_2 PF07648.15 RJW63518.1 - 9e-44 147.4 56.4 1.5e-10 41.0 3.4 6.7 6 0 0 6 6 6 5 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RJW63518.1 - 3.8e-33 113.3 55.9 3.6e-09 36.5 4.1 6.5 6 0 0 6 6 6 5 Kazal-type serine protease inhibitor domain FOLN PF09289.10 RJW63518.1 - 0.71 10.1 14.5 0.15 12.3 2.3 3.2 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain cNMP_binding PF00027.29 RJW63519.1 - 6.7e-19 67.8 0.0 1.1e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RJW63519.1 - 4.8e-07 29.3 5.4 7.4e-07 28.6 5.4 1.3 1 0 0 1 1 1 1 Ion transport protein RhoGEF PF00621.20 RJW63522.1 - 2.9e-25 89.6 0.0 5.8e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.7 RJW63522.1 - 2.3e-10 40.2 1.1 9.5e-08 31.9 0.3 3.6 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.26 RJW63522.1 - 1.5e-06 28.5 0.0 0.011 16.1 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RJW63522.1 - 0.024 15.1 0.0 7.6 7.0 0.0 3.2 3 1 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain PAN_1 PF00024.26 RJW63524.1 - 0.00034 20.5 0.8 0.00034 20.5 0.8 1.9 2 0 0 2 2 2 1 PAN domain C6_DPF PF10170.9 RJW63524.1 - 0.0025 18.1 3.8 0.0039 17.5 3.8 1.3 1 0 0 1 1 1 1 Cysteine-rich domain PAN_4 PF14295.6 RJW63524.1 - 1.1 9.2 6.4 0.16 11.9 1.9 1.8 2 0 0 2 2 2 0 PAN domain Claudin_2 PF13903.6 RJW63525.1 - 6.6e-13 48.8 14.1 9.5e-13 48.3 14.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction 7TM_GPCR_Srh PF10318.9 RJW63525.1 - 0.0041 16.2 3.7 0.0041 16.2 3.7 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh DUF3165 PF11364.8 RJW63525.1 - 0.13 12.6 2.8 0.33 11.3 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) Claudin_3 PF06653.11 RJW63525.1 - 0.22 11.5 15.6 2 8.3 15.6 2.3 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF996 PF06195.13 RJW63528.1 - 3.8 7.8 13.8 3.8 7.8 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF996) NicO PF03824.16 RJW63528.1 - 4.6 6.5 15.0 4.7 6.5 15.0 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein OST3_OST6 PF04756.13 RJW63528.1 - 7.4 5.8 16.1 8.8 5.6 16.1 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Actin PF00022.19 RJW63529.1 - 3.8e-55 187.1 0.0 2.2e-54 184.6 0.0 1.8 1 1 0 1 1 1 1 Actin GerD PF17898.1 RJW63529.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Spore germination GerD central core domain DUF2615 PF11027.8 RJW63530.1 - 0.061 13.5 2.5 0.1 12.8 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Ion_trans_2 PF07885.16 RJW63531.1 - 2.3e-26 91.6 10.3 3.3e-16 59.0 7.4 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 RJW63531.1 - 0.13 11.5 4.5 0.2 10.9 4.5 1.3 1 0 0 1 1 1 0 Ion transport protein zf-ribbon_3 PF13248.6 RJW63533.1 - 0.079 12.4 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Mpv17_PMP22 PF04117.12 RJW63537.1 - 1.7e-17 63.3 1.1 3.4e-17 62.4 1.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family CBP PF12192.8 RJW63538.1 - 0.024 14.8 0.9 0.024 14.8 0.9 2.0 2 0 0 2 2 2 0 Fungal calcium binding protein Pkinase PF00069.25 RJW63541.1 - 2.1e-56 191.2 0.0 7.2e-56 189.5 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63541.1 - 5.6e-36 124.2 0.0 1.7e-35 122.6 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase PKK PF12474.8 RJW63541.1 - 0.00053 20.1 18.5 0.00053 20.1 18.5 4.5 3 2 1 4 4 4 1 Polo kinase kinase ABC1 PF03109.16 RJW63541.1 - 0.74 10.0 7.8 1.7 8.9 0.0 3.5 3 0 0 3 3 3 0 ABC1 family Proteasome PF00227.26 RJW63543.1 - 5.5e-38 130.4 0.2 2.5e-37 128.2 0.2 1.8 1 1 0 1 1 1 1 Proteasome subunit ING PF12998.7 RJW63545.1 - 6.1e-13 49.2 0.9 6.1e-13 49.2 0.9 1.8 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 RJW63545.1 - 4.2e-06 26.6 7.0 7.4e-06 25.8 7.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 RJW63545.1 - 0.014 15.6 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Sec5 PF15469.6 RJW63545.1 - 0.023 14.5 1.1 0.023 14.5 1.1 1.6 2 0 0 2 2 2 0 Exocyst complex component Sec5 zf-RING-like PF08746.11 RJW63545.1 - 1.5 9.1 4.1 3.3 8.1 4.1 1.6 1 0 0 1 1 1 0 RING-like domain SecY PF00344.20 RJW63546.1 - 9.5e-72 241.8 13.1 1.2e-71 241.5 13.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 RJW63546.1 - 9e-15 54.2 0.0 2.9e-14 52.6 0.0 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2975 PF11188.8 RJW63546.1 - 0.41 10.5 5.3 0.61 10.0 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF1430 PF07242.11 RJW63546.1 - 0.52 10.6 6.0 0.73 10.1 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1430) Ribosomal_S11 PF00411.19 RJW63547.1 - 3.4e-44 149.7 1.1 4.7e-44 149.3 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Mito_carr PF00153.27 RJW63548.1 - 8.8e-40 134.6 0.0 2.3e-17 62.7 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein OST3_OST6 PF04756.13 RJW63549.1 - 1.4e-72 244.6 0.0 1.9e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 RJW63549.1 - 0.0078 16.2 0.0 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin SCAMP PF04144.13 RJW63549.1 - 0.03 14.6 2.4 0.045 14.1 2.4 1.2 1 0 0 1 1 1 0 SCAMP family WD40 PF00400.32 RJW63551.1 - 5e-06 27.2 7.8 0.041 14.8 0.0 5.0 4 1 1 5 5 5 2 WD domain, G-beta repeat eIF3m_C_helix PF18005.1 RJW63553.1 - 0.018 14.7 0.2 0.032 13.9 0.2 1.4 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Gryzun-like PF12742.7 RJW63553.1 - 0.067 13.2 0.3 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking CALCOCO1 PF07888.11 RJW63554.1 - 0.00088 18.3 8.7 0.0013 17.7 8.6 1.3 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 RJW63554.1 - 0.0028 16.6 3.6 0.004 16.1 3.6 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3450 PF11932.8 RJW63554.1 - 0.0028 17.0 1.0 0.0039 16.5 1.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) FapA PF03961.13 RJW63554.1 - 0.0042 15.8 0.3 0.0042 15.8 0.3 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A Fib_alpha PF08702.10 RJW63554.1 - 0.0068 16.6 1.7 0.01 16.1 0.7 1.6 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 RJW63554.1 - 0.018 15.1 3.8 0.018 15.1 3.8 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Potyvirid-P3 PF13608.6 RJW63554.1 - 0.026 13.6 0.2 0.037 13.1 0.1 1.3 1 1 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF1843 PF08898.10 RJW63554.1 - 0.079 13.5 0.4 0.6 10.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Cupin_4 PF08007.12 RJW63554.1 - 0.14 11.6 0.9 0.18 11.3 0.6 1.4 1 1 0 1 1 1 0 Cupin superfamily protein Spc24 PF08286.11 RJW63554.1 - 0.3 11.3 3.8 0.56 10.5 0.5 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4200 PF13863.6 RJW63554.1 - 0.32 11.4 8.0 0.043 14.2 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FlaC_arch PF05377.11 RJW63554.1 - 0.48 10.9 7.0 0.69 10.3 0.3 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GrpE PF01025.19 RJW63554.1 - 0.78 9.4 6.5 0.24 11.0 1.3 2.0 1 1 1 2 2 2 0 GrpE zf-Mss51 PF13824.6 RJW63554.1 - 0.86 9.8 3.7 0.41 10.8 0.5 2.1 3 0 0 3 3 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Swi5 PF07061.11 RJW63554.1 - 0.98 9.6 4.5 31 4.7 4.5 2.5 1 1 0 1 1 1 0 Swi5 ABC_tran_CTD PF16326.5 RJW63554.1 - 4.9 7.5 9.1 2.2 8.6 4.5 2.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 RJW63554.1 - 7.5 6.8 11.4 3.4 7.9 7.3 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 fn3 PF00041.21 RJW63555.1 - 0.00059 20.1 0.2 0.44 10.9 0.0 3.3 3 0 0 3 3 3 2 Fibronectin type III domain Not1 PF04054.15 RJW63559.1 - 2e-99 333.0 2.5 7.7e-55 186.3 0.2 2.7 2 0 0 2 2 2 2 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 RJW63559.1 - 7.2e-76 254.5 0.1 1.3e-75 253.7 0.1 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 RJW63559.1 - 2.3e-43 147.6 0.1 9.4e-43 145.6 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 RJW63559.1 - 1.8e-39 135.0 2.2 9.5e-39 132.7 2.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) zf-C2H2_4 PF13894.6 RJW63560.1 - 0.00062 20.4 7.3 0.074 13.9 1.6 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW63560.1 - 0.00073 19.9 6.8 0.084 13.4 1.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW63560.1 - 0.05 13.9 0.4 0.56 10.6 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RJW63560.1 - 0.056 13.9 0.8 5.6 7.6 0.3 3.1 2 0 0 2 2 2 0 Zinc-finger double domain RVT_1 PF00078.27 RJW63561.1 - 7.1e-45 153.2 0.0 1.4e-44 152.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW63561.1 - 5.4e-07 29.5 0.0 1.6e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW63561.1 - 6.7e-07 29.1 1.1 1.8e-06 27.7 0.4 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family IFT57 PF10498.9 RJW63561.1 - 0.0027 16.7 6.5 0.0027 16.7 6.5 2.4 2 1 1 3 3 3 1 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 RJW63561.1 - 0.0033 17.5 2.7 0.85 9.7 3.5 2.6 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 RJW63561.1 - 0.024 12.2 15.0 0.038 11.5 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EMP24_GP25L PF01105.24 RJW63561.1 - 0.055 13.4 1.3 0.15 12.0 1.3 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ATG16 PF08614.11 RJW63561.1 - 0.07 13.3 13.9 0.18 12.0 13.9 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Macoilin PF09726.9 RJW63561.1 - 0.07 11.7 5.8 0.12 10.9 5.8 1.2 1 0 0 1 1 1 0 Macoilin family AvrM-A PF18241.1 RJW63561.1 - 0.076 13.4 6.0 0.59 10.5 5.3 2.5 3 0 0 3 3 3 0 Flax-rust effector AvrM-A Laminin_II PF06009.12 RJW63561.1 - 0.11 12.5 7.2 0.11 12.5 4.6 2.3 2 0 0 2 2 2 0 Laminin Domain II PIN_8 PF18476.1 RJW63561.1 - 0.12 12.2 5.4 0.24 11.2 5.4 1.4 1 0 0 1 1 1 0 PIN like domain DUF4407 PF14362.6 RJW63561.1 - 0.14 11.5 9.5 0.29 10.4 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LUC7 PF03194.15 RJW63561.1 - 0.21 11.2 6.7 0.38 10.4 6.7 1.3 1 0 0 1 1 1 0 LUC7 N_terminus GAS PF13851.6 RJW63561.1 - 0.25 10.7 20.0 0.054 12.8 8.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Occludin_ELL PF07303.13 RJW63561.1 - 0.28 11.9 9.3 0.11 13.2 5.1 2.5 2 0 0 2 2 2 0 Occludin homology domain Atg14 PF10186.9 RJW63561.1 - 0.31 10.1 5.8 0.63 9.1 5.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 RJW63561.1 - 0.43 11.0 13.9 0.89 10.0 13.9 1.5 1 0 0 1 1 1 0 Fez1 EzrA PF06160.12 RJW63561.1 - 0.43 8.7 12.1 0.69 8.0 11.6 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Filament PF00038.21 RJW63561.1 - 0.45 10.1 17.7 0.42 10.1 15.5 2.0 1 1 0 1 1 1 0 Intermediate filament protein HrpB7 PF09486.10 RJW63561.1 - 0.63 10.4 16.9 0.39 11.1 12.9 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) V_ATPase_I PF01496.19 RJW63561.1 - 0.67 7.8 4.1 0.99 7.2 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Csm1_N PF18504.1 RJW63561.1 - 1.4 9.3 14.5 1.2 9.6 2.6 3.1 2 1 1 3 3 3 0 Csm1 N-terminal domain TMF_TATA_bd PF12325.8 RJW63561.1 - 1.8 8.8 19.4 1.2 9.4 16.0 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding T3SS_needle_E PF08988.10 RJW63561.1 - 2.1 8.6 12.6 1.7 8.8 1.3 4.5 2 1 2 4 4 4 0 Type III secretion system, cytoplasmic E component of needle UPF0242 PF06785.11 RJW63561.1 - 2.1 8.4 15.8 4.1 7.5 15.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 RJW63561.1 - 4.2 7.1 16.8 58 3.3 16.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 RJW63561.1 - 5.1 5.9 18.5 10 4.9 18.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 RJW63561.1 - 5.4 7.1 9.5 1.1 9.3 4.0 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Vfa1 PF08432.10 RJW63561.1 - 5.7 7.2 9.7 10 6.4 9.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YabA PF06156.13 RJW63561.1 - 5.9 7.6 8.2 6.3 7.5 5.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA TMPIT PF07851.13 RJW63561.1 - 7.8 5.6 11.7 13 4.9 11.0 1.6 1 1 0 1 1 1 0 TMPIT-like protein BAR PF03114.18 RJW63565.1 - 1.3e-37 129.7 9.0 1.6e-37 129.4 9.0 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 RJW63565.1 - 4.2e-05 22.8 8.0 5.4e-05 22.5 8.0 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking CobA_CobO_BtuR PF02572.15 RJW63565.1 - 0.038 14.2 0.1 0.087 13.1 0.1 1.6 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Endotoxin_C2 PF18449.1 RJW63565.1 - 0.21 11.9 4.7 0.39 11.1 2.1 2.6 2 0 0 2 2 2 0 Delta endotoxin DUF1908 PF08926.11 RJW63566.1 - 0.064 12.3 0.5 0.062 12.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) CitX PF03802.14 RJW63566.1 - 0.13 12.0 0.4 0.2 11.4 0.4 1.2 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Peptidase_M17_N PF02789.17 RJW63566.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain PC_rep PF01851.22 RJW63569.1 - 3.3e-30 103.0 29.5 7e-05 23.1 0.4 9.5 9 0 0 9 9 9 7 Proteasome/cyclosome repeat RPN2_C PF18004.1 RJW63569.1 - 2.1e-25 89.5 16.8 2.1e-25 89.5 16.8 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 RJW63569.1 - 4.7e-17 62.1 5.0 7.5e-12 45.5 0.0 4.3 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 RJW63569.1 - 0.009 16.5 0.3 22 5.7 0.0 4.2 3 0 0 3 3 3 1 HEAT-like repeat DUF1702 PF08012.11 RJW63569.1 - 0.033 13.1 0.3 2.4 7.0 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1702) HEAT PF02985.22 RJW63569.1 - 0.036 14.3 0.0 1 9.8 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat PACT_coil_coil PF10495.9 RJW63569.1 - 1.1 9.9 4.3 2.8 8.6 0.0 2.7 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein MULE PF10551.9 RJW63570.1 - 1.5e-10 41.3 0.0 3.3e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DDOST_48kD PF03345.14 RJW63571.1 - 9e-135 449.7 0.2 1.1e-134 449.4 0.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Ax_dynein_light PF10211.9 RJW63572.1 - 4.8e-95 316.8 13.0 5.7e-95 316.6 13.0 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain RIB43A PF05914.12 RJW63572.1 - 0.00023 20.1 12.8 0.00023 20.1 12.8 1.5 1 1 0 1 1 1 1 RIB43A UPF0242 PF06785.11 RJW63572.1 - 0.00088 19.4 5.7 0.00088 19.4 5.7 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus TSNAXIP1_N PF15739.5 RJW63572.1 - 0.0019 18.6 13.2 0.54 10.6 10.3 2.5 1 1 1 2 2 2 2 Translin-associated factor X-interacting N-terminus HALZ PF02183.18 RJW63572.1 - 0.021 15.0 3.7 0.56 10.5 0.3 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Striatin PF08232.12 RJW63572.1 - 0.22 12.1 10.5 0.51 10.9 10.5 1.6 1 0 0 1 1 1 0 Striatin family FapA PF03961.13 RJW63572.1 - 0.24 10.0 4.3 0.3 9.7 4.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A End3 PF12761.7 RJW63572.1 - 0.26 11.5 9.1 0.077 13.2 5.8 1.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Syntaxin-6_N PF09177.11 RJW63572.1 - 0.36 11.4 10.1 0.051 14.1 5.8 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF5320 PF17253.2 RJW63572.1 - 0.51 11.4 7.7 8.3 7.5 0.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) APG6_N PF17675.1 RJW63572.1 - 0.82 10.2 20.9 3.4 8.2 21.0 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region Remorin_C PF03763.13 RJW63572.1 - 1.6 8.6 11.9 3.4 7.6 11.9 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region Jnk-SapK_ap_N PF09744.9 RJW63572.1 - 2 8.6 19.9 37 4.5 19.9 2.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF724 PF05266.14 RJW63572.1 - 2.5 7.9 12.0 1.4 8.7 10.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 RJW63572.1 - 4.1 8.4 16.2 4.1 8.4 13.5 2.2 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain OmpH PF03938.14 RJW63572.1 - 6.3 7.1 14.9 8.8 6.7 12.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 RJW63572.1 - 8.7 6.2 19.1 0.24 11.2 4.7 2.9 2 1 1 3 3 3 0 Septum formation initiator DUF1515 PF07439.11 RJW63572.1 - 9.4 6.3 7.5 3.1 7.9 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Arrestin_C PF02752.22 RJW63574.1 - 1.5e-16 61.0 0.0 3.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RJW63574.1 - 1.1e-07 32.1 0.0 5.6e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain RYDR_ITPR PF01365.21 RJW63575.1 - 3.1e-131 434.9 0.7 2.6e-79 265.4 0.0 2.8 2 0 0 2 2 2 2 RIH domain RyR PF02026.16 RJW63575.1 - 4.7e-109 356.8 0.3 8.6e-29 99.6 0.0 5.1 5 0 0 5 5 5 4 RyR domain SPRY PF00622.28 RJW63575.1 - 3.3e-49 166.0 0.0 1.1e-20 74.0 0.0 4.2 4 1 0 4 4 4 3 SPRY domain Ins145_P3_rec PF08709.11 RJW63575.1 - 1.4e-39 135.5 0.0 4.4e-38 130.6 0.0 2.3 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 RJW63575.1 - 4.3e-34 118.0 0.7 5.3e-27 94.9 0.1 3.3 3 0 0 3 3 3 3 MIR domain RIH_assoc PF08454.11 RJW63575.1 - 0.078 12.8 0.1 2.1 8.3 0.0 3.0 2 1 0 2 2 2 0 RyR and IP3R Homology associated Prefoldin PF02996.17 RJW63576.1 - 1.5e-25 89.4 0.4 1.8e-25 89.2 0.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DEDD_Tnp_IS110 PF01548.17 RJW63576.1 - 0.00063 19.6 1.4 0.52 10.2 0.2 2.1 2 0 0 2 2 2 2 Transposase Prefoldin_2 PF01920.20 RJW63576.1 - 0.0048 16.8 2.4 0.52 10.3 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit ING PF12998.7 RJW63576.1 - 0.0093 16.5 1.2 0.1 13.2 0.1 2.2 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding BORCS7 PF16088.5 RJW63576.1 - 0.045 14.0 4.1 0.057 13.7 0.9 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF1664 PF07889.12 RJW63576.1 - 0.05 13.6 0.6 1.3 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 RJW63576.1 - 0.057 13.5 3.0 0.071 13.2 0.2 2.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 RJW63576.1 - 0.071 13.3 3.3 4.4 7.5 0.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1759 PF03564.15 RJW63576.1 - 0.08 12.9 0.2 2 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) E2F_CC-MB PF16421.5 RJW63577.1 - 3.2e-26 91.5 0.6 3.2e-26 91.5 0.6 1.7 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 RJW63577.1 - 3.8e-24 84.5 0.2 8.7e-24 83.4 0.1 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Baculo_PEP_C PF04513.12 RJW63577.1 - 0.025 14.6 0.3 0.042 13.9 0.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 RJW63577.1 - 0.029 14.6 2.9 0.029 14.6 2.9 2.2 3 0 0 3 3 3 0 Haemolysin XhlA JIP_LZII PF16471.5 RJW63577.1 - 0.095 12.9 1.2 0.17 12.1 1.2 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II TSC21 PF15217.6 RJW63582.1 - 0.065 13.2 0.0 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 TSC21 family Noc2 PF03715.13 RJW63583.1 - 1.2e-70 238.1 2.4 5.7e-46 157.1 1.3 2.3 2 0 0 2 2 2 2 Noc2p family RVT_1 PF00078.27 RJW63583.1 - 1e-11 44.8 0.0 2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CN_hydrolase PF00795.22 RJW63583.1 - 0.047 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase RB_A PF01858.17 RJW63583.1 - 0.065 13.1 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain Nop14 PF04147.12 RJW63583.1 - 1.7 6.7 29.4 0.4 8.8 0.1 2.4 2 1 0 2 2 2 0 Nop14-like family Symplekin_C PF12295.8 RJW63584.1 - 1.4e-63 214.4 0.4 2.6e-63 213.5 0.4 1.5 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 RJW63584.1 - 3.8e-08 33.3 0.0 9e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Peptidase_A17 PF05380.13 RJW63586.1 - 2.8e-19 69.7 0.0 7.7e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 RJW63586.1 - 0.00013 21.6 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TetR_C_27 PF17935.1 RJW63586.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain gag-asp_proteas PF13975.6 RJW63586.1 - 0.071 13.7 0.0 0.29 11.7 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1759 PF03564.15 RJW63586.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) zf-C2H2 PF00096.26 RJW63587.1 - 6.8e-11 42.0 40.6 0.00099 19.4 3.0 5.2 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW63587.1 - 1.9e-09 37.6 29.8 0.0097 16.7 2.2 5.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RJW63587.1 - 0.012 15.9 1.2 0.061 13.6 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 RJW63587.1 - 0.016 15.2 29.3 0.18 11.8 0.8 4.8 5 0 0 5 5 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW63587.1 - 0.016 15.6 30.5 0.1 13.1 2.4 6.3 6 1 0 6 6 6 0 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 RJW63587.1 - 0.045 13.4 0.1 0.045 13.4 0.1 4.2 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 RJW63587.1 - 0.13 12.7 0.2 0.13 12.7 0.2 5.3 6 0 0 6 6 5 0 Zinc-finger of C2H2 type LAGLIDADG_2 PF03161.13 RJW63587.1 - 0.15 12.0 0.3 0.32 11.0 0.1 1.7 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family zf-C2H2_11 PF16622.5 RJW63587.1 - 0.19 11.5 26.2 4.8 7.0 1.6 4.9 4 0 0 4 4 4 0 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 RJW63587.1 - 0.28 11.1 0.1 0.28 11.1 0.1 3.6 3 1 0 3 3 3 0 SprT-like zinc ribbon domain GAGA PF09237.11 RJW63587.1 - 0.4 10.5 8.8 0.48 10.3 0.1 3.3 3 0 0 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.7 RJW63587.1 - 5.8 7.3 15.5 8.7 6.7 6.2 4.3 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 RJW63587.1 - 6.8 5.8 7.2 12 5.0 0.2 2.8 1 1 2 3 3 3 0 Putative actin-like family Peptidase_C2 PF00648.21 RJW63589.1 - 1.8e-116 388.3 0.0 2.4e-116 387.9 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RJW63589.1 - 1.2e-43 148.7 0.0 2e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 RJW63589.1 - 1.6e-08 33.8 0.2 9.8e-06 25.1 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RJW63589.1 - 8.7e-07 28.1 0.0 8.4e-05 21.9 0.2 2.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 RJW63589.1 - 0.01 15.3 0.5 0.11 12.1 0.3 2.5 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 RJW63589.1 - 0.033 14.6 0.7 0.37 11.3 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF1_GNE PF00736.19 RJW63590.1 - 2.1e-34 117.5 1.9 3.7e-34 116.8 0.3 2.1 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 RJW63590.1 - 3e-13 49.9 6.5 6.4e-13 48.9 6.5 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region DUF1640 PF07798.11 RJW63590.1 - 0.0014 18.7 2.4 0.0022 18.0 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.12 RJW63590.1 - 0.0038 17.3 0.2 0.006 16.6 0.2 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.11 RJW63590.1 - 0.014 15.5 2.3 0.014 15.5 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) BLOC1_2 PF10046.9 RJW63590.1 - 0.024 15.0 4.2 0.04 14.2 2.4 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 RJW63590.1 - 0.024 12.6 1.2 0.033 12.2 1.2 1.1 1 0 0 1 1 1 0 Prominin TRPM_tetra PF16519.5 RJW63590.1 - 0.025 14.7 2.8 0.066 13.3 2.8 1.7 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Cupin_4 PF08007.12 RJW63590.1 - 0.061 12.8 0.2 0.079 12.4 0.2 1.2 1 0 0 1 1 1 0 Cupin superfamily protein tRNA-synt_2c PF01411.19 RJW63590.1 - 0.086 11.3 0.3 0.11 10.9 0.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) LpxB PF02684.15 RJW63590.1 - 0.089 11.6 0.3 0.13 11.1 0.3 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase FlgN PF05130.12 RJW63590.1 - 0.12 12.9 4.1 0.16 12.5 3.8 1.5 1 1 0 1 1 1 0 FlgN protein V_ATPase_I PF01496.19 RJW63590.1 - 0.16 9.8 0.2 0.17 9.8 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med9 PF07544.13 RJW63590.1 - 0.69 10.0 5.1 1.4 9.1 5.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.11 RJW63590.1 - 0.98 9.9 6.3 0.7 10.3 0.7 2.6 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF4123 PF13503.6 RJW63594.1 - 0.11 12.9 0.9 0.22 11.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) rve PF00665.26 RJW63596.1 - 1.2e-12 48.1 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RJW63596.1 - 0.0027 17.5 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Imm70 PF15601.6 RJW63597.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 70 zf-C2H2_2 PF12756.7 RJW63598.1 - 2.5e-11 43.8 0.1 1.6e-10 41.2 0.1 2.2 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 RJW63598.1 - 0.087 13.0 1.0 3.3 7.9 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Rap1_C PF11626.8 RJW63599.1 - 0.032 14.3 0.1 0.097 12.8 0.1 1.9 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Nop10p PF04135.12 RJW63600.1 - 7.4e-21 73.9 0.6 8.6e-21 73.7 0.6 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family ELYS-bb PF16687.5 RJW63601.1 - 8.6e-20 70.8 0.7 3.5e-14 52.3 0.0 2.6 3 0 0 3 3 3 2 beta-propeller of ELYS nucleoporin WW PF00397.26 RJW63602.1 - 9.4e-07 28.8 0.9 2.5e-06 27.4 0.9 1.8 1 0 0 1 1 1 1 WW domain YL1 PF05764.13 RJW63602.1 - 1.2e-05 25.5 12.3 1.6e-05 25.1 12.3 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Zn_Tnp_IS91 PF14319.6 RJW63602.1 - 0.046 13.8 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain Nop14 PF04147.12 RJW63602.1 - 6.2 4.9 14.9 8.6 4.4 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family RNB PF00773.19 RJW63603.1 - 3.5e-74 250.1 0.0 5.6e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 RJW63603.1 - 2.3e-22 78.8 0.0 7.9e-22 77.1 0.0 2.0 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 RJW63603.1 - 1.7e-05 24.9 0.2 0.0022 18.1 0.0 2.8 3 0 0 3 3 3 1 Cold shock domain Rrp44_CSD1 PF17216.3 RJW63603.1 - 0.021 14.6 0.0 0.059 13.1 0.0 1.7 1 1 0 1 1 1 0 Rrp44-like cold shock domain zf-CW PF07496.15 RJW63603.1 - 0.14 12.2 0.6 27 4.9 0.1 2.6 2 0 0 2 2 2 0 CW-type Zinc Finger DOCK-C2 PF14429.6 RJW63604.1 - 6.9e-44 150.0 0.0 1.5e-43 148.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 RJW63604.1 - 9e-11 42.2 0.0 2.4e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) RVT_1 PF00078.27 RJW63605.1 - 1.8e-46 158.4 0.5 7.6e-46 156.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) BRO1 PF03097.18 RJW63605.1 - 2.6e-34 118.7 3.7 4.4e-34 117.9 3.7 1.3 1 0 0 1 1 1 1 BRO1-like domain Exo_endo_phos_2 PF14529.6 RJW63605.1 - 1.1e-11 44.6 0.0 6e-11 42.2 0.0 2.3 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase zf-CCHC_2 PF13696.6 RJW63606.1 - 0.0036 17.1 0.8 0.0091 15.8 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 RJW63606.1 - 0.0038 17.2 0.8 0.0083 16.2 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 RJW63606.1 - 0.0081 16.7 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease AlgF PF11182.8 RJW63606.1 - 0.016 15.0 0.5 0.025 14.3 0.0 1.5 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF RVP PF00077.20 RJW63606.1 - 0.023 15.0 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 RJW63606.1 - 0.12 13.1 0.0 0.25 12.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Nucleoporin_C PF03177.14 RJW63607.1 - 1.2e-09 37.5 0.0 3.6e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 RJW63607.1 - 1.6e-07 30.4 0.0 3.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Peptidase_C97 PF05903.14 RJW63608.1 - 2.2e-37 128.2 0.0 3.2e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_C2 PF00648.21 RJW63609.1 - 9.5e-117 389.2 0.0 1.3e-116 388.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RJW63609.1 - 1.5e-42 145.2 0.0 2.7e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_8 PF13833.6 RJW63609.1 - 5.6e-10 38.9 0.5 1.4e-06 28.1 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW63609.1 - 1.6e-06 27.2 10.1 5.9e-05 22.3 0.7 3.6 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 RJW63609.1 - 1.6e-06 28.4 0.3 0.13 12.7 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW63609.1 - 3.7e-06 26.4 7.5 1.5e-05 24.6 0.4 4.3 5 0 0 5 5 5 1 EF-hand domain EF-hand_5 PF13202.6 RJW63609.1 - 0.22 11.1 1.3 2.1 8.0 1.1 2.5 2 0 0 2 2 2 0 EF hand Pkinase PF00069.25 RJW63610.1 - 4.2e-76 255.8 0.0 6.4e-76 255.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63610.1 - 2.1e-42 145.2 0.0 3.3e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW63610.1 - 1.2e-08 34.6 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 RJW63610.1 - 2.8e-06 27.0 0.1 6.3e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.22 RJW63610.1 - 5.7e-06 26.0 0.7 1.2e-05 25.0 0.7 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RJW63610.1 - 0.0078 15.6 0.4 0.014 14.7 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW63610.1 - 0.02 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family RVT_1 PF00078.27 RJW63610.1 - 0.039 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Haspin_kinase PF12330.8 RJW63610.1 - 0.04 12.9 0.4 0.084 11.8 0.4 1.4 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 RJW63610.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MRP-S34 PF16053.5 RJW63612.1 - 1.4e-36 125.0 0.0 2.4e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 V-set PF07686.17 RJW63613.1 - 5.6e-21 74.8 17.7 0.012 15.8 0.0 12.0 12 0 0 12 12 12 8 Immunoglobulin V-set domain I-set PF07679.16 RJW63613.1 - 1.2e-11 44.5 1.3 5.3 7.2 0.0 10.2 11 0 0 11 11 11 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW63613.1 - 2.4e-06 28.1 15.9 45 4.7 0.0 13.0 15 0 0 15 15 15 0 Immunoglobulin domain Izumo-Ig PF16706.5 RJW63613.1 - 0.00011 22.2 0.6 16 5.6 0.0 6.9 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 RJW63613.1 - 0.00022 21.5 29.9 4.8 7.6 0.0 13.1 15 0 0 15 15 15 1 Immunoglobulin domain zf-C2H2 PF00096.26 RJW63614.1 - 7.7e-18 63.9 58.8 0.00051 20.3 1.6 6.7 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW63614.1 - 3.9e-14 52.1 54.8 0.021 15.6 2.0 6.9 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW63614.1 - 4e-09 36.5 47.8 0.0044 17.4 3.7 8.1 8 1 0 8 8 8 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW63614.1 - 4.9e-05 23.2 12.7 0.011 15.7 0.6 5.2 6 0 0 6 6 4 3 C2H2-type zinc finger zf-met PF12874.7 RJW63614.1 - 0.00027 21.2 24.8 0.0051 17.2 1.1 6.3 6 0 0 6 6 6 1 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 RJW63614.1 - 0.0025 18.5 9.6 0.12 13.1 0.7 3.5 2 1 1 3 3 3 1 zinc-ribbon family zf-C2H2_jaz PF12171.8 RJW63614.1 - 0.0042 17.3 26.4 1.8 8.9 0.3 6.4 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding Rpr2 PF04032.16 RJW63614.1 - 0.01 16.1 5.9 0.18 12.1 0.2 3.2 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GAGA PF09237.11 RJW63614.1 - 0.025 14.4 7.7 0.99 9.3 0.2 3.6 2 1 1 3 3 3 0 GAGA factor Mut7-C PF01927.16 RJW63614.1 - 0.037 14.1 11.3 6.1 6.9 0.1 4.2 2 1 3 5 5 5 0 Mut7-C RNAse domain UPF0515 PF15135.6 RJW63614.1 - 0.085 12.2 11.0 0.86 8.9 0.9 3.4 2 1 1 3 3 3 0 Uncharacterised protein UPF0515 Spt46 PF17734.1 RJW63614.1 - 0.1 12.4 9.6 1.7 8.4 0.1 3.2 2 1 1 3 3 3 0 Spermatogenesis-associated protein 46 PHF5 PF03660.14 RJW63614.1 - 0.14 12.4 5.5 1.6 9.0 0.0 2.9 2 1 0 2 2 2 0 PHF5-like protein zf-C2HE PF16278.5 RJW63614.1 - 0.17 12.3 32.6 1.3 9.6 1.3 4.7 4 1 1 5 5 4 0 C2HE / C2H2 / C2HC zinc-binding finger CFC PF09443.10 RJW63614.1 - 0.18 11.7 20.0 0.29 11.0 0.1 4.7 5 0 0 5 5 5 0 Cripto_Frl-1_Cryptic (CFC) UspB PF10625.9 RJW63614.1 - 0.5 10.4 3.1 18 5.4 0.4 2.4 2 0 0 2 2 2 0 Universal stress protein B (UspB) zf-ACC PF17848.1 RJW63614.1 - 0.72 10.0 11.5 6.5 6.9 0.1 4.3 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zf-FCS PF06467.14 RJW63614.1 - 1.3 9.0 18.7 13 5.9 0.1 5.3 6 0 0 6 6 5 0 MYM-type Zinc finger with FCS sequence motif Zn_ribbon_SprT PF17283.2 RJW63614.1 - 1.4 8.9 24.8 4.5 7.3 2.6 4.4 4 0 0 4 4 4 0 SprT-like zinc ribbon domain Terminase_GpA PF05876.12 RJW63614.1 - 2.2 6.7 7.6 0.62 8.5 0.5 2.2 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) DUF3268 PF11672.8 RJW63614.1 - 2.3 8.6 7.7 18 5.7 0.1 2.8 2 1 0 2 2 2 0 zinc-finger-containing domain zf-C2H2_8 PF15909.5 RJW63614.1 - 3.4 8.0 22.3 0.2 11.9 0.7 3.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 RJW63614.1 - 4.9 7.3 20.7 22 5.3 0.1 5.2 5 1 0 5 5 5 0 Zinc ribbon domain DUF5318 PF17249.2 RJW63614.1 - 7 6.4 7.4 9 6.1 0.8 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5318) zf_UBZ PF18439.1 RJW63614.1 - 7.4 6.3 24.8 5.2 6.8 0.1 5.9 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Pkinase_Tyr PF07714.17 RJW63616.1 - 7.2e-30 104.1 0.8 2.6e-23 82.6 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW63616.1 - 5.4e-28 98.1 0.0 2.5e-25 89.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 RJW63616.1 - 7.5e-10 38.1 3.4 2.1e-09 36.7 3.4 1.8 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 RJW63616.1 - 1.7e-05 25.8 10.2 1.7e-05 25.8 10.2 2.6 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 RJW63616.1 - 0.0016 17.3 0.0 0.0033 16.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase FdtA PF05523.11 RJW63617.1 - 0.029 14.1 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal FYRN PF05964.14 RJW63617.1 - 0.075 12.9 0.2 1 9.2 0.0 2.6 2 1 0 2 2 2 0 F/Y-rich N-terminus Es2 PF09751.9 RJW63618.1 - 5.8e-38 131.8 4.7 1e-23 84.8 0.2 3.3 3 0 0 3 3 3 3 Nuclear protein Es2 Ets PF00178.22 RJW63619.1 - 9.5e-32 109.3 0.5 1.9e-31 108.4 0.5 1.5 1 0 0 1 1 1 1 Ets-domain Pox_F17 PF04767.12 RJW63619.1 - 0.024 15.1 1.4 0.062 13.8 1.4 1.7 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein zf-CXXC PF02008.20 RJW63621.1 - 1.1e-15 57.3 19.2 1.1e-15 57.3 19.2 2.9 3 0 0 3 3 3 1 CXXC zinc finger domain PHD PF00628.29 RJW63621.1 - 3.1e-11 43.0 9.7 3.1e-11 43.0 9.7 3.2 3 0 0 3 3 3 1 PHD-finger EF-hand_7 PF13499.6 RJW63622.1 - 2.4e-12 47.1 1.3 2.5e-08 34.2 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW63622.1 - 3.5e-12 45.2 0.1 1.4e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RJW63622.1 - 1.8e-11 42.7 0.1 3e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 RJW63622.1 - 4.8e-07 29.0 0.0 0.00014 21.2 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW63622.1 - 1.8e-05 24.5 1.2 0.08 12.8 0.2 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 RJW63622.1 - 0.00036 20.8 0.0 0.019 15.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain DUF3349 PF11829.8 RJW63622.1 - 0.014 16.1 0.0 0.13 13.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) ECH_1 PF00378.20 RJW63624.1 - 1.7e-49 168.4 0.0 2.2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RJW63624.1 - 1.2e-20 74.4 0.0 1.8e-19 70.4 0.0 2.0 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase PRK PF00485.18 RJW63626.1 - 9.9e-30 103.7 0.0 1.3e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family BRCT PF00533.26 RJW63628.1 - 1.3e-43 147.2 0.0 3.9e-10 40.0 0.0 7.6 7 1 0 7 7 7 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 RJW63628.1 - 6.5e-43 144.5 9.8 1.8e-17 63.0 0.8 7.9 9 1 0 9 9 9 5 twin BRCT domain BRCT_2 PF16589.5 RJW63628.1 - 7.6e-28 96.8 0.0 3.2e-05 24.3 0.0 7.8 8 0 0 8 8 8 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RJW63628.1 - 6.4e-13 48.4 0.0 8e-07 28.9 0.0 4.8 5 0 0 5 5 5 3 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 RJW63628.1 - 7.5e-10 39.0 0.5 3.3 8.0 0.1 7.3 7 1 0 7 7 7 4 DNA ligase 3 BRCT domain Usp PF00582.26 RJW63629.1 - 2.2e-26 93.1 0.0 2.6e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Asparaginase PF00710.20 RJW63630.1 - 1.7e-58 197.3 0.0 2.8e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 RJW63630.1 - 3e-24 85.4 0.1 5.4e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 RJW63630.1 - 3.1e-17 62.9 0.3 8e-09 36.0 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW63630.1 - 1.3e-14 54.3 0.6 9.7e-08 32.4 0.1 4.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW63630.1 - 1.6e-14 53.8 0.1 5.8e-09 36.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW63630.1 - 6.3e-10 38.4 0.6 0.0034 17.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RJW63630.1 - 1.4e-05 25.3 1.2 0.9 10.1 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RJW63631.1 - 5.9e-11 42.8 0.1 1.8e-10 41.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW63631.1 - 3e-10 40.2 1.9 7.9e-09 35.6 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RJW63631.1 - 1.3e-09 38.1 0.7 0.0021 18.4 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RJW63631.1 - 4.7e-09 35.8 0.4 0.0059 17.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 RJW63631.1 - 1.5e-05 25.5 0.3 0.024 15.2 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (many copies) SNF2_N PF00176.23 RJW63632.1 - 5.7e-56 189.7 0.1 1.1e-55 188.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW63632.1 - 1.8e-12 47.5 0.5 3.2e-11 43.5 0.5 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ADD_ATRX PF17981.1 RJW63632.1 - 3e-09 36.6 0.3 8.6e-09 35.1 0.3 1.8 1 0 0 1 1 1 1 Cysteine Rich ADD domain ResIII PF04851.15 RJW63632.1 - 7.2e-07 29.4 0.0 2.9e-06 27.4 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2340 PF10209.9 RJW63632.1 - 0.023 15.2 0.1 0.1 13.0 0.1 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) PHD PF00628.29 RJW63632.1 - 0.19 11.7 12.7 0.097 12.6 9.7 2.2 2 0 0 2 2 2 0 PHD-finger Prenyltrans PF00432.21 RJW63633.1 - 1.5e-61 203.8 7.0 4.4e-14 51.9 0.2 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 RJW63633.1 - 4.2e-05 22.8 0.0 0.028 13.5 0.0 3.0 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 RJW63633.1 - 5.7e-05 22.4 0.0 0.0058 15.8 0.0 2.7 1 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain Bromo_TP PF07524.13 RJW63635.1 - 1e-06 28.7 0.1 2.3e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 RJW63635.1 - 4.9e-06 26.7 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Histone-fold protein PHD PF00628.29 RJW63635.1 - 2.7e-05 24.0 0.4 6.1e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 PHD-finger JAKMIP_CC3 PF16034.5 RJW63636.1 - 2.4e-06 27.7 14.8 2.4e-06 27.7 14.8 5.4 3 2 2 5 5 5 2 JAKMIP CC3 domain Dimer_Tnp_hAT PF05699.14 RJW63636.1 - 0.053 13.3 0.1 0.19 11.6 0.1 2.0 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Ribonuclease_3 PF00636.26 RJW63636.1 - 0.13 12.9 0.7 0.5 11.0 0.7 2.0 1 0 0 1 1 1 0 Ribonuclease III domain COQ7 PF03232.13 RJW63636.1 - 0.47 10.2 12.3 0.29 10.9 0.7 3.4 2 1 1 3 3 3 0 Ubiquinone biosynthesis protein COQ7 Pox_A_type_inc PF04508.12 RJW63636.1 - 1.4 8.9 13.4 0.31 11.0 0.2 4.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Baculo_PEP_C PF04513.12 RJW63636.1 - 4.8 7.2 28.0 0.14 12.2 0.8 4.9 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4 PF00105.18 RJW63637.1 - 1.6e-22 79.7 16.5 3.5e-22 78.7 16.5 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW63637.1 - 3.5e-07 30.0 4.1 7.5e-06 25.7 0.3 3.6 2 1 1 3 3 3 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 RJW63637.1 - 0.01 15.9 8.5 0.027 14.6 6.8 2.4 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type YIF1 PF03878.15 RJW63638.1 - 1.3e-15 57.6 0.9 1.4e-15 57.5 0.9 1.0 1 0 0 1 1 1 1 YIF1 TctB PF07331.11 RJW63638.1 - 0.031 14.6 2.8 0.036 14.3 2.8 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family C1q PF00386.21 RJW63641.1 - 3.6e-24 85.4 0.0 4.6e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 RJW63641.1 - 1.9e-05 24.6 0.0 3.9e-05 23.5 0.0 1.6 1 1 1 2 2 2 1 BclA C-terminal domain Collagen PF01391.18 RJW63641.1 - 0.0029 17.3 2.0 0.0049 16.6 2.0 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PA14 PF07691.12 RJW63641.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 PA14 domain Snf7 PF03357.21 RJW63643.1 - 1.9e-15 56.9 9.9 2.4e-15 56.6 9.9 1.1 1 0 0 1 1 1 1 Snf7 Ras PF00071.22 RJW63644.1 - 3.2e-57 192.7 0.1 3.6e-57 192.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW63644.1 - 2.2e-22 79.5 0.0 3.2e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW63644.1 - 4.2e-08 32.8 0.1 4.9e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RJW63644.1 - 5.5e-05 23.1 0.8 0.064 13.2 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RJW63644.1 - 0.00063 19.8 0.0 0.00092 19.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RJW63644.1 - 0.0032 17.0 0.1 0.0078 15.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AlkA_N PF06029.11 RJW63644.1 - 0.014 15.7 0.0 0.075 13.3 0.0 1.9 1 1 0 1 1 1 0 AlkA N-terminal domain FSH1 PF03959.13 RJW63645.1 - 4.1e-39 134.4 0.1 1.4e-38 132.7 0.1 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 RJW63645.1 - 0.043 13.1 0.0 0.089 12.0 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF829 PF05705.14 RJW63645.1 - 0.16 11.8 0.0 0.62 9.9 0.0 1.6 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF829) HLH PF00010.26 RJW63647.1 - 4.6e-09 36.1 1.9 1.5e-08 34.5 1.9 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UPF0016 PF01169.19 RJW63648.1 - 1.7e-42 143.6 19.3 1.2e-22 80.0 5.4 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.16 RJW63648.1 - 0.03 14.0 6.5 0.28 10.8 0.3 2.4 2 1 0 2 2 2 0 Integral membrane protein TerC family Mntp PF02659.15 RJW63648.1 - 0.042 13.6 0.1 0.042 13.6 0.1 2.6 2 1 0 2 2 2 0 Putative manganese efflux pump FTR1 PF03239.14 RJW63648.1 - 0.16 11.1 10.4 0.011 14.9 1.9 2.1 1 1 1 2 2 2 0 Iron permease FTR1 family Phage_holin_3_6 PF07332.11 RJW63648.1 - 0.58 10.2 7.2 0.6 10.2 0.0 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Miga PF10265.9 RJW63650.1 - 3.3e-81 273.9 1.2 1e-80 272.3 0.8 1.9 2 0 0 2 2 2 1 Mitoguardin Phosphodiest PF01663.22 RJW63651.1 - 1e-12 48.4 2.1 5.4e-12 46.0 0.2 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RJW63651.1 - 3.9e-05 23.2 0.1 5.6e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 RJW63651.1 - 4.1e-05 23.1 0.0 6.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily RVT_1 PF00078.27 RJW63652.1 - 1.5e-44 152.2 0.0 2.3e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 RJW63652.1 - 6e-35 120.9 0.0 1e-34 120.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63652.1 - 1.8e-28 99.5 0.0 3.3e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 RJW63652.1 - 5.8e-12 44.9 0.2 1.3e-11 43.7 0.2 1.7 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Exo_endo_phos_2 PF14529.6 RJW63652.1 - 7.1e-07 29.1 0.1 2.5e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW63652.1 - 1.1e-06 28.4 1.3 2.9e-06 27.0 0.4 2.2 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family Pkinase_fungal PF17667.1 RJW63652.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Ion_trans PF00520.31 RJW63653.1 - 2.5e-45 154.6 10.3 3.3e-45 154.3 10.3 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RJW63653.1 - 1.4e-27 95.9 0.1 2.5e-27 95.1 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RJW63653.1 - 6.1e-13 48.5 5.7 6.1e-13 48.5 5.7 2.0 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 RJW63653.1 - 0.047 12.4 2.7 0.075 11.7 2.7 1.4 1 0 0 1 1 1 0 Polycystin cation channel BTB_3 PF16017.5 RJW63653.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain VGCC_alpha2 PF08473.11 RJW63655.1 - 3e-11 42.8 0.0 4.9e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd FAM72 PF14976.6 RJW63657.1 - 0.063 13.4 0.3 0.072 13.2 0.3 1.2 1 0 0 1 1 1 0 FAM72 protein RVT_1 PF00078.27 RJW63658.1 - 2.6e-45 154.6 0.0 4.8e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW63658.1 - 5.1e-05 22.9 0.8 0.00011 21.8 0.8 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PRK PF00485.18 RJW63659.1 - 0.0034 17.1 0.0 0.011 15.5 0.0 1.7 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family HEAT_2 PF13646.6 RJW63660.1 - 0.032 14.6 0.6 0.32 11.4 0.1 2.7 2 1 1 3 3 3 0 HEAT repeats DDT PF02791.17 RJW63660.1 - 0.17 12.2 2.7 0.55 10.6 1.1 2.6 3 0 0 3 3 3 0 DDT domain DUF4530 PF15039.6 RJW63660.1 - 1.1 9.5 4.6 6.9 6.8 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) DUF2457 PF10446.9 RJW63660.1 - 1.6 7.8 11.6 2.4 7.2 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EF-hand_6 PF13405.6 RJW63661.1 - 4.2e-09 35.6 0.3 4.4e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RJW63661.1 - 8.4e-09 35.8 0.2 0.00023 21.6 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW63661.1 - 3e-07 29.5 0.4 3.9e-05 22.9 0.0 2.9 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 RJW63661.1 - 4.9e-07 29.5 0.8 0.3 11.0 0.0 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 RJW63661.1 - 1.8e-05 25.0 0.0 0.019 15.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RJW63661.1 - 0.015 14.8 0.7 0.052 13.1 0.0 2.3 2 1 0 2 2 2 0 EF hand WWE PF02825.20 RJW63661.1 - 0.13 12.9 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 WWE domain ThiF PF00899.21 RJW63662.1 - 1.6e-16 60.4 0.0 5.7e-16 58.6 0.0 1.9 1 1 0 1 1 1 1 ThiF family Pribosyltran_N PF13793.6 RJW63663.1 - 1.2e-44 150.9 0.4 3.3e-44 149.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 RJW63663.1 - 1.7e-26 93.4 0.9 8.3e-21 74.8 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Rad51 PF08423.11 RJW63663.1 - 1e-17 64.3 0.1 1e-13 51.2 0.0 2.6 3 0 0 3 3 3 2 Rad51 Pribosyltran PF00156.27 RJW63663.1 - 1.8e-14 53.6 1.0 1.6e-13 50.5 0.4 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain AAA_25 PF13481.6 RJW63663.1 - 5.4e-06 26.1 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 RJW63663.1 - 6.4e-06 25.7 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 RJW63663.1 - 6.7e-05 22.3 0.1 0.00013 21.4 0.1 1.4 1 0 0 1 1 1 1 KaiC UPRTase PF14681.6 RJW63663.1 - 0.00094 18.7 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CLP1_P PF16575.5 RJW63663.1 - 0.079 12.8 0.4 0.29 10.9 0.0 2.1 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RecA PF00154.21 RJW63663.1 - 0.084 12.3 0.0 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 recA bacterial DNA recombination protein PAXNEB PF05625.11 RJW63663.1 - 0.14 11.3 0.1 0.27 10.3 0.1 1.4 1 0 0 1 1 1 0 PAXNEB protein Lar_N PF09861.9 RJW63663.1 - 0.16 11.1 0.2 0.63 9.2 0.0 2.1 3 0 0 3 3 3 0 Lactate racemase N-terminal domain Astacin PF01400.24 RJW63665.1 - 5.4e-36 124.0 0.0 1.5e-35 122.6 0.0 1.8 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) RT_RNaseH PF17917.1 RJW63665.1 - 6.3e-28 97.1 0.1 1.5e-27 95.9 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW63665.1 - 1e-25 89.6 0.4 5e-25 87.4 0.4 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RJW63665.1 - 7.7e-22 77.7 0.0 3.5e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW63665.1 - 2.2e-16 59.7 0.1 6.9e-16 58.1 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain ShK PF01549.24 RJW63665.1 - 4.4e-12 46.3 85.1 9.3e-05 22.9 4.7 7.9 7 0 0 7 7 7 5 ShK domain-like rve_3 PF13683.6 RJW63665.1 - 0.085 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Peptidase_A17 PF05380.13 RJW63665.1 - 0.097 12.7 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Pao retrotransposon peptidase DUF4722 PF15849.5 RJW63665.1 - 0.097 12.4 0.1 0.52 10.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4722) Kin17_mid PF10357.9 RJW63666.1 - 1.2e-44 151.3 0.3 3.4e-44 149.8 0.1 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 RJW63666.1 - 5.4e-13 48.8 1.0 1.2e-12 47.7 1.0 1.6 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain KOW PF00467.29 RJW63666.1 - 0.002 18.0 0.0 0.0083 16.0 0.0 2.1 1 0 0 1 1 1 1 KOW motif Toxin_23 PF08093.11 RJW63666.1 - 1.6 8.9 4.3 0.4 10.9 0.7 1.9 2 0 0 2 2 2 0 Magi 5 toxic peptide family G-alpha PF00503.20 RJW63667.1 - 7.3e-65 219.4 5.7 3.9e-62 210.5 2.7 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 RJW63667.1 - 7e-13 48.4 0.2 1.5e-12 47.3 0.2 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW63667.1 - 0.0033 16.8 0.1 0.0052 16.2 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RJW63667.1 - 0.032 13.8 0.1 0.046 13.2 0.1 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF4476 PF14771.6 RJW63667.1 - 0.063 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Roc PF08477.13 RJW63667.1 - 0.12 12.6 0.1 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase EnY2 PF10163.9 RJW63668.1 - 2.1e-22 79.3 0.0 2.6e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Aldose_epim PF01263.20 RJW63670.1 - 1.1e-52 179.2 0.0 1.4e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Asp_protease_2 PF13650.6 RJW63671.1 - 0.044 14.4 0.0 0.094 13.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease HAT PF02184.16 RJW63672.1 - 1.6e-30 104.7 64.1 2.9e-07 30.3 0.6 14.0 13 2 0 13 13 13 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 RJW63672.1 - 2.4e-23 80.8 28.4 0.011 16.5 0.1 12.1 8 3 5 13 13 11 9 Tetratricopeptide repeat TPR_19 PF14559.6 RJW63672.1 - 1.2e-18 67.3 2.5 0.0015 19.0 0.0 7.9 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 RJW63672.1 - 3.4e-11 43.6 6.0 0.56 10.9 0.0 7.4 6 2 2 8 8 8 4 Tetratricopeptide repeat Suf PF05843.14 RJW63672.1 - 9.7e-10 38.9 47.5 5.8e-06 26.5 7.5 6.6 3 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 RJW63672.1 - 1.5e-09 37.6 0.8 0.00062 20.0 0.0 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW63672.1 - 7e-06 25.8 21.2 4.1 7.8 0.1 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 RJW63672.1 - 0.00016 21.9 13.7 0.81 10.0 0.0 6.9 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 RJW63672.1 - 0.0014 18.7 9.9 14 6.2 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW63672.1 - 0.043 13.9 4.0 19 5.6 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat BSD PF03909.17 RJW63672.1 - 0.1 12.6 1.9 5.8 7.0 0.2 2.8 2 0 0 2 2 2 0 BSD domain TPR_6 PF13174.6 RJW63672.1 - 0.15 12.7 28.6 5 8.0 0.2 9.5 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_9 PF13371.6 RJW63672.1 - 0.34 11.1 9.4 4.8 7.4 0.1 4.9 4 1 0 5 5 5 0 Tetratricopeptide repeat DAO PF01266.24 RJW63674.1 - 3.7e-20 72.8 0.0 1.7e-19 70.6 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase ADH_zinc_N_2 PF13602.6 RJW63674.1 - 0.0056 17.7 0.0 0.011 16.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Topo_Zn_Ribbon PF08272.11 RJW63674.1 - 0.035 13.8 0.1 0.088 12.5 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like NAD_binding_8 PF13450.6 RJW63674.1 - 0.046 13.9 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 RJW63674.1 - 0.046 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 RJW63674.1 - 0.2 12.2 0.0 0.42 11.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BTB PF00651.31 RJW63675.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain EGF PF00008.27 RJW63677.1 - 0.00024 21.3 35.3 0.026 14.8 5.5 5.2 4 0 0 4 4 4 4 EGF-like domain YiaAB PF05360.14 RJW63677.1 - 1 9.7 3.2 0.46 10.8 0.4 1.9 2 0 0 2 2 2 0 yiaA/B two helix domain IQ_SEC7_PH PF16453.5 RJW63678.1 - 1.4e-54 183.8 0.1 2.7e-54 182.9 0.1 1.5 1 0 0 1 1 1 1 PH domain Sec7 PF01369.20 RJW63678.1 - 6.1e-54 182.5 0.0 9.7e-54 181.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_5 PF15405.6 RJW63678.1 - 0.012 15.7 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain T2SSM PF04612.12 RJW63678.1 - 0.055 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M HSA PF07529.13 RJW63679.1 - 1.9e-06 28.1 0.0 5.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 HSA SNF2_N PF00176.23 RJW63679.1 - 2.4e-06 26.5 0.1 9.6e-06 24.5 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain FCH PF00611.23 RJW63680.1 - 5.9e-17 61.7 0.1 2.2e-16 59.9 0.1 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 RJW63680.1 - 3.3e-12 46.0 1.5 8.4e-07 28.8 0.0 4.1 3 1 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 RJW63680.1 - 1.3e-10 40.7 0.0 0.0019 17.8 0.0 4.4 4 0 0 4 4 4 2 SH3 domain SH3_2 PF07653.17 RJW63680.1 - 0.00014 21.5 0.0 0.16 11.7 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain DUF2937 PF11157.8 RJW63680.1 - 0.54 10.0 2.6 4.9 6.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) GDPD PF03009.17 RJW63682.1 - 1.7e-23 83.7 0.0 1.4e-21 77.4 0.0 2.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Med27 PF11571.8 RJW63683.1 - 1.4e-22 79.8 0.7 3e-22 78.8 0.1 1.9 2 0 0 2 2 2 1 Mediator complex subunit 27 Glyco_transf_64 PF09258.10 RJW63684.1 - 4e-54 183.5 0.0 7.9e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 RJW63684.1 - 0.0007 18.9 0.0 0.0029 16.9 0.0 2.0 2 0 0 2 2 2 1 Exostosin family GoLoco PF02188.17 RJW63687.1 - 5.2e-33 112.1 30.6 1.7e-08 33.8 0.2 4.8 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.6 RJW63687.1 - 8.9e-19 67.6 20.5 1.2e-08 35.1 1.8 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 RJW63687.1 - 1.6e-16 59.4 16.4 9.4e-05 22.1 0.9 6.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 RJW63687.1 - 9e-12 44.2 11.3 0.00022 21.2 0.0 6.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 RJW63687.1 - 7.8e-10 38.1 18.9 0.0012 18.7 0.1 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW63687.1 - 1e-06 28.4 23.3 0.014 15.5 0.7 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW63687.1 - 0.003 17.0 0.8 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 MalT-like TPR region SNAP PF14938.6 RJW63687.1 - 0.024 14.1 0.2 0.024 14.1 0.2 2.0 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 RJW63687.1 - 0.029 15.2 7.1 0.43 11.5 0.1 4.8 5 2 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RJW63687.1 - 0.033 14.1 24.3 0.17 11.8 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 RJW63687.1 - 0.076 12.7 8.8 3.6 7.3 0.2 5.0 3 2 1 4 4 4 0 TPR repeat TPR_16 PF13432.6 RJW63687.1 - 1.3 9.7 8.1 3.6 8.3 1.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyphos_transf PF04464.14 RJW63691.1 - 0.0057 15.7 0.0 0.0068 15.4 0.0 1.0 1 0 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase PIG-H PF10181.9 RJW63696.1 - 1.6e-06 27.8 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component IPK PF03770.16 RJW63697.1 - 2e-35 122.5 0.1 5.2e-35 121.1 0.1 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase Innexin PF00876.18 RJW63698.1 - 4.2e-93 312.4 7.4 5.3e-93 312.1 7.4 1.0 1 0 0 1 1 1 1 Innexin SieB PF14163.6 RJW63698.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF4381 PF14316.6 RJW63698.1 - 0.087 13.1 4.4 0.64 10.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Collagen PF01391.18 RJW63699.1 - 1.4e-47 159.2 160.5 1.5e-09 37.4 27.4 6.8 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) LicD PF04991.13 RJW63700.1 - 2.1e-14 54.2 0.0 8.4e-09 35.9 0.1 2.4 2 0 0 2 2 2 2 LicD family Glft2_N PF17994.1 RJW63701.1 - 0.047 13.6 0.1 0.059 13.3 0.1 1.2 1 0 0 1 1 1 0 Galactofuranosyltransferase 2 N-terminal LicD PF04991.13 RJW63703.1 - 1.5e-06 28.5 0.0 0.0059 16.8 0.0 2.2 2 0 0 2 2 2 2 LicD family SEA PF01390.20 RJW63705.1 - 0.0069 16.5 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 SEA domain DUF5626 PF18540.1 RJW63705.1 - 0.071 13.6 0.0 0.1 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5626) NIF PF03031.18 RJW63707.1 - 1.1e-18 67.5 0.1 9.1e-18 64.5 0.1 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HDV_ag PF01517.18 RJW63709.1 - 0.021 14.7 2.2 0.022 14.5 0.2 1.9 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen TAF8_C PF10406.9 RJW63709.1 - 1.1 9.9 3.3 2.9 8.5 3.0 1.9 1 1 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Pkinase PF00069.25 RJW63710.1 - 3.4e-74 249.6 0.0 4.6e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63710.1 - 1.5e-42 145.7 0.0 2.2e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 RJW63710.1 - 8.6e-19 67.1 0.0 1.6e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 RJW63710.1 - 7.4e-07 28.8 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA PF00627.31 RJW63710.1 - 0.0018 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Kdo PF06293.14 RJW63710.1 - 0.0064 15.9 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RJW63710.1 - 0.0083 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.11 RJW63710.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Haspin_kinase PF12330.8 RJW63710.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RJW63710.1 - 0.22 11.4 0.2 1.1 9.1 0.1 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Paramyxo_C PF01692.18 RJW63710.1 - 0.59 9.5 1.8 2.1 7.7 1.8 1.9 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C Ribosomal_L7Ae PF01248.26 RJW63711.1 - 7.6e-23 80.1 0.6 1.1e-22 79.6 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase_Tyr PF07714.17 RJW63712.1 - 8e-90 300.6 0.0 1.1e-89 300.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW63712.1 - 3.9e-41 141.2 0.0 5.7e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 RJW63712.1 - 0.00043 20.4 0.0 0.00088 19.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain APH PF01636.23 RJW63712.1 - 0.00052 20.0 0.1 0.88 9.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family ig PF00047.25 RJW63712.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Kinase-like PF14531.6 RJW63712.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CotJA PF11007.8 RJW63712.1 - 0.025 14.4 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) DUF2207 PF09972.9 RJW63713.1 - 0.00044 19.1 0.7 0.00059 18.7 0.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Wzy_C PF04932.15 RJW63713.1 - 2.6 7.7 10.2 0.6 9.7 6.3 1.9 2 0 0 2 2 2 0 O-Antigen ligase LicD PF04991.13 RJW63714.1 - 7.1e-16 59.0 0.4 9.2e-10 39.0 0.0 2.6 3 0 0 3 3 3 2 LicD family Cofilin_ADF PF00241.20 RJW63720.1 - 2.6e-11 43.4 0.0 2.7e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein E1-E2_ATPase PF00122.20 RJW63722.1 - 1.7e-30 105.9 1.6 3.7e-30 104.8 0.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 RJW63722.1 - 1.1e-23 83.7 0.4 4.4e-23 81.7 0.4 2.1 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 RJW63722.1 - 3.7e-17 63.3 0.0 1.9e-09 38.2 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RJW63722.1 - 1.4e-05 25.0 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) AGTRAP PF06396.11 RJW63722.1 - 0.0034 17.2 1.0 0.0084 15.9 0.1 2.1 2 0 0 2 2 2 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Hydrolase_3 PF08282.12 RJW63722.1 - 0.062 13.0 0.0 9.8 5.8 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RJW63723.1 - 2.1e-31 108.9 0.1 2.1e-31 108.9 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RJW63723.1 - 8e-17 62.2 0.0 4.6e-07 30.3 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 RJW63723.1 - 5e-08 33.1 0.3 3.2e-07 30.5 0.0 2.5 3 0 0 3 3 3 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 RJW63723.1 - 2.4e-07 30.8 0.0 5.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Pkinase PF00069.25 RJW63724.1 - 1e-66 225.0 0.0 1.4e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63724.1 - 4.7e-31 108.0 0.0 7.1e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW63724.1 - 0.0033 16.8 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Tub_N PF16322.5 RJW63724.1 - 0.0098 16.3 3.6 0.03 14.7 3.6 1.8 1 0 0 1 1 1 1 Tubby N-terminal APH PF01636.23 RJW63724.1 - 0.023 14.6 2.4 0.079 12.9 2.4 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW63724.1 - 0.071 12.0 5.1 0.096 11.6 0.1 3.2 3 1 0 3 3 3 0 Haspin like kinase domain Kdo PF06293.14 RJW63724.1 - 0.18 11.2 0.5 0.36 10.2 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vir_act_alpha_C PF10400.9 RJW63727.1 - 0.04 14.6 0.0 0.053 14.2 0.0 1.2 1 0 0 1 1 1 0 Virulence activator alpha C-term zf-CCCH_3 PF15663.5 RJW63727.1 - 0.061 13.5 0.1 0.07 13.4 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger containing family 7tm_1 PF00001.21 RJW63728.1 - 3.1e-28 98.8 22.0 4.2e-27 95.1 20.7 2.8 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF4817 PF16087.5 RJW63729.1 - 2.8e-17 62.3 0.0 5.1e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) Peptidase_S10 PF00450.22 RJW63730.1 - 1.2e-118 397.1 0.1 1.4e-118 397.0 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 RJW63731.1 - 9e-27 94.5 0.5 1.1e-26 94.2 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DOT1 PF08123.13 RJW63735.1 - 1.5e-69 233.7 0.0 4.6e-69 232.1 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 DHC_N1 PF08385.12 RJW63735.1 - 0.12 11.0 0.8 0.18 10.4 0.8 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Osmo_CC PF08946.10 RJW63735.1 - 0.36 11.1 3.5 1.2 9.4 3.5 1.9 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DivIC PF04977.15 RJW63735.1 - 5.6 6.8 6.1 29 4.5 0.4 2.7 2 0 0 2 2 2 0 Septum formation initiator Peptidase_S10 PF00450.22 RJW63736.1 - 8.5e-47 160.5 0.0 9.6e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PAP2 PF01569.21 RJW63737.1 - 3.6e-14 52.7 10.7 1e-13 51.2 4.0 3.7 3 2 1 4 4 4 1 PAP2 superfamily Kinesin PF00225.23 RJW63738.1 - 1.2e-90 303.8 0.0 1.9e-90 303.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 RJW63738.1 - 3.6e-36 123.5 0.0 1.2e-35 121.8 0.0 2.0 2 0 0 2 2 2 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 RJW63738.1 - 1e-17 64.4 0.0 3.2e-15 56.4 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding V-SNARE PF05008.15 RJW63738.1 - 0.37 11.2 2.6 1.9 8.9 1.5 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Alpha-amylase PF00128.24 RJW63739.1 - 1.5e-22 80.6 0.8 5.2e-18 65.7 1.0 2.6 2 1 0 2 2 2 2 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 RJW63739.1 - 2.1e-15 56.0 0.1 3.8e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus UPF0183 PF03676.14 RJW63740.1 - 2.9e-93 313.2 0.0 3.8e-91 306.3 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) Fapy_DNA_glyco PF01149.24 RJW63741.1 - 0.082 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase N-terminal domain FERM_C PF09380.10 RJW63741.1 - 0.1 13.0 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 FERM C-terminal PH-like domain PPR_2 PF13041.6 RJW63742.1 - 6.2e-15 55.1 0.0 5.2e-06 26.6 0.0 4.8 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 RJW63742.1 - 6.2e-09 35.8 0.0 0.00072 19.6 0.0 4.7 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 RJW63742.1 - 0.0013 18.4 0.1 8.6 6.2 0.0 4.8 6 0 0 6 6 6 1 PPR repeat PPR PF01535.20 RJW63742.1 - 0.0017 18.5 2.7 6.4 7.3 0.0 4.5 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 RJW63742.1 - 0.002 17.5 0.1 0.25 10.7 0.0 2.8 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP BTAD PF03704.17 RJW63742.1 - 0.022 15.2 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Cadherin_pro PF08758.11 RJW63742.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Cadherin prodomain like IQ PF00612.27 RJW63743.1 - 3.3e-08 32.6 8.3 3.8e-05 23.1 0.8 3.5 3 0 0 3 3 3 2 IQ calmodulin-binding motif DUF4862 PF16154.5 RJW63743.1 - 0.022 14.2 0.1 0.027 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4862) Na_Ca_ex PF01699.24 RJW63744.1 - 2.8e-17 63.1 7.5 4.2e-17 62.5 7.5 1.3 1 1 0 1 1 1 1 Sodium/calcium exchanger protein PTB PF08416.13 RJW63745.1 - 3.1e-08 33.8 0.0 7.6e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotyrosine-binding domain SH2 PF00017.24 RJW63745.1 - 1.9e-07 31.1 0.0 4.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain DUF525 PF04379.14 RJW63745.1 - 0.026 14.8 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 ApaG domain SH2_2 PF14633.6 RJW63745.1 - 0.087 12.2 0.0 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 SH2 domain FERM_N PF09379.10 RJW63746.1 - 1.1e-11 44.4 0.0 1.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 RJW63746.1 - 5.4e-05 23.6 0.2 0.0024 18.3 0.0 2.4 3 0 0 3 3 3 1 FERM central domain HLH PF00010.26 RJW63747.1 - 1.5e-13 50.5 1.1 3.4e-13 49.3 1.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 RJW63747.1 - 1.3e-09 38.1 1.0 3.3e-09 36.8 1.0 1.7 1 0 0 1 1 1 1 Hairy Orange LSM PF01423.22 RJW63748.1 - 1.5e-16 59.9 0.4 1.8e-16 59.6 0.4 1.1 1 0 0 1 1 1 1 LSM domain TPH PF13868.6 RJW63751.1 - 2.6e-59 200.5 126.4 5.5e-50 169.9 94.8 3.1 2 1 1 3 3 3 2 Trichohyalin-plectin-homology domain Dynein_light PF01221.18 RJW63752.1 - 1.4e-24 86.2 0.0 1.5e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_M15_3 PF08291.11 RJW63752.1 - 0.055 13.6 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase M15 Hex_IIIa PF02455.16 RJW63754.1 - 0.14 11.0 0.6 0.19 10.5 0.6 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Ldh_2 PF02615.14 RJW63755.1 - 3.1e-93 312.6 0.2 3.5e-93 312.4 0.2 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase JHD PF17811.1 RJW63757.1 - 0.032 14.8 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 Jumonji helical domain TPR_9 PF13371.6 RJW63757.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Mito_carr PF00153.27 RJW63758.1 - 1.1e-58 195.2 3.7 1e-20 73.4 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Lumazine_bd_2 PF12893.7 RJW63759.1 - 0.056 14.1 0.0 1.6 9.5 0.0 2.9 3 0 0 3 3 3 0 Putative lumazine-binding DUF3426 PF11906.8 RJW63759.1 - 0.12 12.5 0.1 0.32 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Il2rg PF15874.5 RJW63760.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative Interleukin 2 receptor, gamma chain Methyltr_RsmB-F PF01189.17 RJW63762.1 - 6.4e-30 104.3 0.0 1.3e-26 93.5 0.0 3.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RJW63762.1 - 0.0076 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase EMP24_GP25L PF01105.24 RJW63762.1 - 0.041 13.8 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD STN1_2 PF09170.10 RJW63762.1 - 0.048 13.9 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF778 PF05608.12 RJW63763.1 - 2.1e-32 113.0 3.3 6.8e-19 69.0 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF4796 PF16044.5 RJW63763.1 - 0.0016 18.1 0.4 0.0035 16.9 0.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4796) LAP1C PF05609.12 RJW63766.1 - 8 5.4 88.9 15 4.5 88.9 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TRAP_alpha PF03896.16 RJW63767.1 - 1.6e-05 24.3 1.4 1.7e-05 24.2 1.4 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 RJW63767.1 - 2.7e-05 22.5 8.9 2.7e-05 22.5 8.9 1.1 1 0 0 1 1 1 1 DNA polymerase phi DUF2946 PF11162.8 RJW63767.1 - 0.0036 18.0 1.4 0.0044 17.7 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) CobT PF06213.12 RJW63767.1 - 0.31 10.4 12.1 0.37 10.1 12.1 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Polyoma_lg_T_C PF06431.11 RJW63767.1 - 0.46 9.3 3.0 0.48 9.2 3.0 1.0 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Osteopontin PF00865.18 RJW63767.1 - 0.5 9.8 23.8 0.57 9.6 23.8 1.0 1 0 0 1 1 1 0 Osteopontin NOA36 PF06524.12 RJW63767.1 - 0.65 9.3 22.1 0.84 8.9 22.1 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 RJW63767.1 - 1.2 9.2 9.5 1.7 8.6 9.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 RJW63767.1 - 1.2 7.3 10.5 1.3 7.2 10.5 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 RJW63767.1 - 1.8 8.3 8.8 2.6 7.7 8.8 1.4 1 1 0 1 1 1 0 FAM176 family Utp14 PF04615.13 RJW63767.1 - 2.2 6.7 8.8 2.3 6.7 8.8 1.0 1 0 0 1 1 1 0 Utp14 protein Sporozoite_P67 PF05642.11 RJW63767.1 - 2.6 6.0 5.5 3 5.8 5.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 RJW63767.1 - 3.8 5.9 12.7 4 5.9 12.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CNDH2_C PF16858.5 RJW63767.1 - 5.3 6.8 7.4 5.6 6.8 7.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term TFB6 PF17110.5 RJW63767.1 - 6.2 6.5 9.1 7.7 6.2 9.1 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop14 PF04147.12 RJW63767.1 - 9.4 4.3 16.1 11 4.1 16.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF938 PF06080.12 RJW63768.1 - 0.035 13.9 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Herpes_U26 PF07402.11 RJW63768.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus U26 protein ATP-grasp_2 PF08442.10 RJW63769.1 - 9.5e-63 211.4 0.0 1.8e-62 210.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 RJW63769.1 - 4.5e-26 91.5 1.0 7.5e-26 90.8 1.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 RJW63769.1 - 0.034 14.0 0.4 0.21 11.4 0.1 2.1 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 RJW63769.1 - 0.039 13.4 0.1 0.14 11.6 0.1 2.0 1 1 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 RJW63769.1 - 0.054 13.3 0.0 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peripla_BP_3 PF13377.6 RJW63769.1 - 0.14 12.5 0.1 4.5 7.6 0.1 2.5 1 1 0 2 2 2 0 Periplasmic binding protein-like domain Ribonuclease_T2 PF00445.18 RJW63770.1 - 5.6e-46 157.1 0.1 6.4e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family HTH_8 PF02954.19 RJW63770.1 - 0.23 11.3 0.2 1.6 8.6 0.2 2.2 1 1 0 1 1 1 0 Bacterial regulatory protein, Fis family TBCC PF07986.12 RJW63771.1 - 5e-30 103.7 0.0 8.2e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 RJW63771.1 - 2.3e-20 73.2 1.6 3.2e-14 53.4 0.1 2.4 2 0 0 2 2 2 2 Tubulin-specific chaperone C N-terminal domain MASE2 PF05230.11 RJW63775.1 - 0.034 14.2 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 MASE2 domain CD34_antigen PF06365.12 RJW63776.1 - 0.00065 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family DAG1 PF05454.11 RJW63776.1 - 0.019 14.4 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF5527 PF17665.1 RJW63776.1 - 0.19 11.3 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5527) DUF2207 PF09972.9 RJW63776.1 - 0.2 10.4 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 RJW63776.1 - 0.39 10.6 11.1 26 4.7 11.1 2.3 1 1 0 1 1 1 0 TMEM154 protein family DUF4083 PF13314.6 RJW63776.1 - 3.9 7.5 7.3 8.8 6.4 5.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) PA28_beta PF02252.18 RJW63777.1 - 4.9e-57 191.7 0.6 7.9e-57 191.0 0.6 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 RJW63777.1 - 2.5e-12 46.7 0.2 5.2e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit DUF1676 PF07898.13 RJW63778.1 - 9.1 6.3 10.5 12 5.9 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) NAPRTase_N PF17767.1 RJW63779.1 - 1.1e-40 138.9 0.0 2.1e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 RJW63779.1 - 2.6e-36 124.4 0.3 4.6e-36 123.6 0.3 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 RJW63779.1 - 3e-06 27.0 0.0 0.028 14.0 0.0 2.3 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.16 RJW63779.1 - 0.005 16.9 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribonuclease_T2 PF00445.18 RJW63780.1 - 1.1e-13 51.9 0.0 1.4e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Pet191_N PF10203.9 RJW63780.1 - 0.064 13.6 0.5 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Pkinase PF00069.25 RJW63781.1 - 1.3e-45 155.9 0.0 1.8e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63781.1 - 6e-29 101.1 0.0 2.9e-26 92.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW63781.1 - 0.025 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ribonuclease_T2 PF00445.18 RJW63782.1 - 6.9e-11 42.7 0.1 8.4e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Oxidored_q3 PF00499.20 RJW63782.1 - 0.068 12.9 2.8 0.092 12.5 2.8 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 zf-C3HC4_3 PF13920.6 RJW63783.1 - 5.4e-06 26.2 9.3 1.9e-05 24.4 9.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW63783.1 - 0.00055 20.2 12.7 0.0014 18.9 12.7 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 RJW63783.1 - 0.0043 16.9 9.0 0.018 14.9 9.0 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RJW63783.1 - 0.045 13.7 11.0 0.12 12.3 11.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Trm112p PF03966.16 RJW63783.1 - 0.17 12.5 1.1 0.37 11.4 0.4 1.9 2 0 0 2 2 2 0 Trm112p-like protein Pinin_SDK_memA PF04696.13 RJW63785.1 - 4.8e-29 101.0 13.7 1.4e-28 99.5 13.7 1.9 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region Pinin_SDK_N PF04697.13 RJW63785.1 - 1.3e-09 38.8 0.0 1.3e-09 38.8 0.0 4.2 3 2 1 5 5 5 1 pinin/SDK conserved region Prefoldin PF02996.17 RJW63785.1 - 0.19 11.6 0.2 0.19 11.6 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit Hormone_recep PF00104.30 RJW63786.1 - 3.9e-30 105.0 0.0 6.5e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RJW63786.1 - 3.8e-28 97.7 15.7 6.4e-28 97.0 15.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Herpes_U26 PF07402.11 RJW63788.1 - 0.035 13.7 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus U26 protein CaKB PF03185.15 RJW63792.1 - 2.3e-19 69.9 6.8 3.1e-19 69.4 6.8 1.1 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit Sec23_trunk PF04811.15 RJW63793.1 - 7.8e-69 231.9 0.0 1.1e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 RJW63793.1 - 2.8e-27 94.5 0.2 5.8e-27 93.5 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RJW63793.1 - 9.1e-27 93.6 0.0 1.9e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 RJW63793.1 - 3.1e-12 46.3 10.2 6e-12 45.4 10.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 RJW63793.1 - 9.8e-09 35.0 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat RWD PF05773.22 RJW63794.1 - 0.055 13.7 0.4 0.096 13.0 0.4 1.7 1 1 0 1 1 1 0 RWD domain Gag_p30 PF02093.16 RJW63794.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Gag P30 core shell protein RVT_1 PF00078.27 RJW63795.1 - 7.5e-09 35.4 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EMI PF07546.13 RJW63797.1 - 0.062 14.1 0.2 0.11 13.2 0.2 1.5 1 0 0 1 1 1 0 EMI domain Ald_Xan_dh_C2 PF02738.18 RJW63797.1 - 0.17 10.3 0.0 0.18 10.3 0.0 1.0 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase EpCAM_N PF18635.1 RJW63798.1 - 0.098 12.8 1.2 0.098 12.8 1.2 2.7 3 0 0 3 3 3 0 Epithelial cell adhesion molecule N-terminal domain IL15 PF02372.15 RJW63802.1 - 0.16 12.0 0.7 0.36 10.8 0.7 1.5 1 0 0 1 1 1 0 Interleukin 15 JHD PF17811.1 RJW63802.1 - 0.17 12.4 1.6 0.4 11.2 1.3 1.8 1 1 0 1 1 1 0 Jumonji helical domain Prominin PF05478.11 RJW63802.1 - 0.5 8.3 3.5 0.65 7.9 3.5 1.2 1 0 0 1 1 1 0 Prominin FapA PF03961.13 RJW63802.1 - 3.6 6.1 4.9 6.8 5.2 4.9 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A RVT_1 PF00078.27 RJW63803.1 - 1.1e-12 47.9 0.0 1.9e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tektin PF03148.14 RJW63805.1 - 4.1e-99 331.9 47.3 4.7e-99 331.7 47.3 1.0 1 0 0 1 1 1 1 Tektin family Tropomyosin_1 PF12718.7 RJW63805.1 - 0.0038 17.4 2.2 0.0038 17.4 2.2 4.4 3 1 1 4 4 4 1 Tropomyosin like KapB PF08810.10 RJW63805.1 - 0.029 14.5 1.1 0.14 12.4 1.1 2.1 1 0 0 1 1 1 0 Kinase associated protein B DUF1664 PF07889.12 RJW63805.1 - 0.033 14.2 22.1 0.099 12.7 3.6 4.1 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF2935 PF11155.8 RJW63805.1 - 0.17 12.2 11.3 9.2e+02 0.2 11.5 3.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) BEX PF04538.12 RJW63805.1 - 0.44 11.1 3.0 0.58 10.8 0.7 2.4 2 0 0 2 2 2 0 Brain expressed X-linked like family HrpB7 PF09486.10 RJW63805.1 - 0.79 10.1 26.0 0.1 13.0 2.8 4.3 1 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) FlaC_arch PF05377.11 RJW63805.1 - 2.3 8.7 13.0 0.11 12.9 0.9 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 RJW63805.1 - 6 7.3 31.1 0.04 14.4 9.2 2.8 2 1 1 3 3 3 0 Fez1 Plk4_PB2 PF18409.1 RJW63805.1 - 7.8 7.2 14.4 18 6.1 1.3 4.6 3 2 2 5 5 5 0 Polo-like Kinase 4 Polo Box 2 AWS PF17907.1 RJW63806.1 - 2e-10 40.6 4.5 3.7e-10 39.7 4.5 1.4 1 0 0 1 1 1 1 AWS domain CAP PF00188.26 RJW63809.1 - 2.3e-12 47.9 0.0 7.1e-12 46.3 0.0 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family WW PF00397.26 RJW63810.1 - 9.3e-23 80.0 1.3 1.5e-11 44.2 0.1 2.5 2 0 0 2 2 2 2 WW domain C2 PF00168.30 RJW63810.1 - 5.9e-08 32.9 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF3480 PF11979.8 RJW63813.1 - 5.9e-41 140.6 0.0 4.3e-21 75.3 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF3480) Serpin PF00079.20 RJW63814.1 - 0.0019 17.6 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Forkhead PF00250.18 RJW63816.1 - 8.1e-37 125.4 0.0 1.9e-36 124.2 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain AKAP7_NLS PF10469.9 RJW63818.1 - 2.4e-37 128.8 0.0 3.1e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 RJW63818.1 - 3.2e-09 36.5 0.0 6.7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 KH domain ADIP PF11559.8 RJW63819.1 - 0.00024 21.2 57.0 0.0033 17.5 14.3 3.9 1 1 3 4 4 4 3 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 RJW63819.1 - 0.0041 17.2 4.0 0.0041 17.2 4.0 3.5 2 1 1 3 3 3 1 Laminin Domain II Tropomyosin_1 PF12718.7 RJW63819.1 - 0.0093 16.1 3.5 0.0093 16.1 3.5 4.3 1 1 2 3 3 3 1 Tropomyosin like HrpB7 PF09486.10 RJW63819.1 - 0.011 16.2 37.7 0.14 12.5 17.8 3.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lebercilin PF15619.6 RJW63819.1 - 0.013 15.2 55.5 0.18 11.4 6.2 2.8 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 RJW63819.1 - 0.016 14.1 54.1 0.22 10.4 26.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 RJW63819.1 - 0.016 13.9 48.3 0.022 13.4 18.5 2.0 1 1 1 2 2 2 0 AAA domain DUF4618 PF15397.6 RJW63819.1 - 0.054 12.9 48.9 0.022 14.2 34.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) PKcGMP_CC PF16808.5 RJW63819.1 - 0.077 12.9 10.4 0.12 12.2 0.0 4.4 4 1 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HCMV_UL139 PF12507.8 RJW63819.1 - 0.079 13.3 13.5 1.9 8.9 13.5 2.6 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein HMMR_N PF15905.5 RJW63819.1 - 0.099 12.1 58.0 1.3 8.4 31.4 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 RJW63819.1 - 0.17 10.2 59.0 1 7.6 11.0 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein Cep57_CLD_2 PF14197.6 RJW63819.1 - 0.31 11.1 43.4 0.069 13.2 6.5 4.9 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 DUF2935 PF11155.8 RJW63819.1 - 0.34 11.3 12.3 2.2e+02 2.2 12.3 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Spectrin PF00435.21 RJW63819.1 - 0.55 10.7 41.1 0.12 12.9 6.6 3.4 1 1 2 3 3 3 0 Spectrin repeat Fib_alpha PF08702.10 RJW63819.1 - 0.78 9.9 46.4 0.91 9.7 5.6 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 RJW63819.1 - 0.79 10.4 57.4 0.044 14.4 14.3 4.3 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 RJW63819.1 - 1.1 9.4 63.1 0.53 10.5 18.7 3.3 1 1 1 2 2 1 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 RJW63819.1 - 1.6 8.0 51.4 0.16 11.3 13.6 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 RJW63819.1 - 1.8 8.6 58.1 0.038 14.1 20.3 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 RJW63819.1 - 2.1 8.8 55.1 0.22 12.0 33.6 2.9 1 1 2 3 3 3 0 Fez1 DUF1664 PF07889.12 RJW63819.1 - 2.8 8.0 36.4 3.7 7.6 9.3 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HAP1_N PF04849.13 RJW63819.1 - 2.8 7.0 59.2 4.8 6.3 21.4 2.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 RJW63819.1 - 4.8 6.4 43.4 0.96 8.7 21.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 RJW63819.1 - 6.3 5.6 56.1 4.5 6.0 52.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) SET PF00856.28 RJW63821.1 - 5.9e-16 59.3 1.9 8.3e-16 58.8 0.1 2.2 2 1 0 2 2 2 1 SET domain WW PF00397.26 RJW63821.1 - 2e-12 47.0 0.2 6.2e-12 45.4 0.1 1.9 2 0 0 2 2 2 1 WW domain SRI PF08236.11 RJW63821.1 - 6.8e-11 42.2 0.0 1.7e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.11 RJW63821.1 - 4 7.5 4.6 1.9 8.6 1.1 2.3 2 0 0 2 2 2 0 TFIIS helical bundle-like domain NolV PF06635.12 RJW63823.1 - 0.17 11.2 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein NolV Pribosyltran PF00156.27 RJW63824.1 - 9.3e-17 61.0 0.1 1.5e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Sugar_tr PF00083.24 RJW63825.1 - 7.7e-98 328.3 18.0 1.2e-97 327.7 18.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW63825.1 - 2e-23 82.9 28.0 5.3e-23 81.5 24.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PsbN PF02468.15 RJW63825.1 - 1.4 8.9 4.8 19 5.2 0.8 3.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Pribosyltran PF00156.27 RJW63826.1 - 1.2e-17 63.8 0.0 1.6e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Peptidase_M28 PF04389.17 RJW63827.1 - 1.3e-08 34.8 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 RJW63827.1 - 2e-07 30.7 0.0 3.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Acyltransferase PF01553.21 RJW63828.1 - 2.7e-19 69.1 0.0 4.6e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase EGF PF00008.27 RJW63829.1 - 0.037 14.3 0.5 0.037 14.3 0.5 6.3 5 1 0 5 5 5 0 EGF-like domain EGF_alliinase PF04863.13 RJW63829.1 - 0.6 10.6 7.1 0.2 12.1 2.6 2.6 2 0 0 2 2 2 0 Alliinase EGF-like domain cEGF PF12662.7 RJW63829.1 - 1.2 9.1 15.7 2.2 8.3 2.0 4.7 4 0 0 4 4 4 0 Complement Clr-like EGF-like Seipin PF06775.14 RJW63830.1 - 3.1e-27 96.0 0.1 5.3e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) SpoIIE PF07228.12 RJW63830.1 - 6.5e-10 39.2 0.0 1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 RJW63830.1 - 0.00066 19.4 0.0 0.0066 16.1 0.0 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.21 RJW63830.1 - 0.0058 16.3 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C eRF1_2 PF03464.15 RJW63833.1 - 1.2e-46 158.3 0.0 2e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 RJW63833.1 - 1.3e-37 128.7 0.1 3.7e-37 127.2 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 RJW63833.1 - 1.6e-20 73.4 0.0 2.5e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 RJW63833.1 - 2.4e-10 40.8 0.0 3.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 RJW63833.1 - 1.7e-09 38.0 0.0 2.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 GIY-YIG PF01541.24 RJW63834.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain MRP-S27 PF10037.9 RJW63835.1 - 1.5e-61 208.5 1.9 2.3e-51 174.9 1.8 2.2 1 1 1 2 2 2 2 Mitochondrial 28S ribosomal protein S27 MVP_shoulder PF11978.8 RJW63835.1 - 0.18 11.8 0.6 6.9 6.7 0.1 3.0 3 0 0 3 3 3 0 Shoulder domain EGF_Tenascin PF18720.1 RJW63837.1 - 0.0048 16.9 6.5 0.017 15.2 1.5 3.1 2 0 0 2 2 2 1 Tenascin EGF domain EGF PF00008.27 RJW63837.1 - 0.043 14.1 0.9 0.043 14.1 0.9 6.5 5 2 0 5 5 5 0 EGF-like domain hEGF PF12661.7 RJW63837.1 - 0.78 10.5 21.2 9.1 7.1 2.1 5.4 4 0 0 4 4 4 0 Human growth factor-like EGF Fijivirus_P9-2 PF06837.11 RJW63838.1 - 7.1 6.0 8.4 29 4.0 0.1 2.2 2 0 0 2 2 2 0 Fijivirus P9-2 protein GAF_3 PF13492.6 RJW63839.1 - 0.001 19.4 0.0 0.0034 17.7 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 RJW63839.1 - 0.0038 17.5 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 RJW63839.1 - 0.0081 16.8 0.0 0.056 14.1 0.0 2.3 2 0 0 2 2 2 1 GAF domain NAF PF03822.14 RJW63839.1 - 0.028 14.6 9.6 1 9.6 0.4 3.3 3 0 0 3 3 3 0 NAF domain Dpy-30 PF05186.13 RJW63839.1 - 0.13 12.0 0.1 24 4.7 0.0 3.4 3 0 0 3 3 3 0 Dpy-30 motif RVT_1 PF00078.27 RJW63842.1 - 4.1e-07 29.8 0.0 7.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 RJW63843.1 - 7.8e-14 51.2 0.3 1.2e-07 31.4 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RJW63843.1 - 3.4e-09 36.8 2.8 1.1e-06 28.9 0.0 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW63843.1 - 0.00016 21.2 0.1 0.00029 20.4 0.1 1.5 1 1 0 1 1 1 1 Leucine-rich repeat Pribosyltran PF00156.27 RJW63845.1 - 1.9e-18 66.5 0.0 2.7e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RJW63845.1 - 0.071 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Lyase_1 PF00206.20 RJW63848.1 - 1.9e-89 300.2 0.0 2.3e-88 296.6 0.0 2.1 1 1 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 RJW63848.1 - 4.3e-21 75.1 0.2 1.2e-20 73.7 0.2 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus GlcNAc-1_reg PF18440.1 RJW63849.1 - 0.069 13.4 0.6 6.1 7.2 0.2 2.7 2 1 1 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain Serpin PF00079.20 RJW63850.1 - 3e-84 283.5 0.0 3.4e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) UPF0506 PF11703.8 RJW63851.1 - 1e-13 51.4 24.3 1.3e-13 51.1 24.3 1.1 1 0 0 1 1 1 1 UPF0506 Dickkopf_N PF04706.12 RJW63851.1 - 0.0064 16.9 24.2 0.048 14.1 24.3 2.0 1 1 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region Conotoxin_I2 PF17557.2 RJW63851.1 - 0.033 14.3 9.7 0.033 14.3 9.7 2.3 2 0 0 2 2 2 0 I2-superfamily conotoxins Toxin_23 PF08093.11 RJW63851.1 - 9.7 6.4 18.8 1.1 9.4 6.8 2.6 2 0 0 2 2 2 0 Magi 5 toxic peptide family PAP_assoc PF03828.19 RJW63853.1 - 5.1e-14 52.2 1.3 5.4e-12 45.7 0.5 3.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RJW63853.1 - 1.6e-05 25.1 0.0 9.9e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-CCHC PF00098.23 RJW63853.1 - 0.0025 17.8 2.2 0.0025 17.8 2.2 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_6 PF15288.6 RJW63853.1 - 0.012 15.4 0.6 0.012 15.4 0.6 3.2 2 0 0 2 2 2 0 Zinc knuckle Polbeta PF18765.1 RJW63853.1 - 0.023 14.8 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-CCHC_4 PF14392.6 RJW63853.1 - 2.2 8.1 4.2 12 5.7 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 RJW63853.1 - 3.2 7.7 16.2 0.076 12.9 1.1 3.3 3 0 0 3 3 3 0 Zinc knuckle Aldedh PF00171.22 RJW63854.1 - 5.8e-89 298.7 0.6 7.2e-89 298.4 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family I-set PF07679.16 RJW63855.1 - 0.00015 21.7 0.0 0.66 10.1 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW63855.1 - 0.00017 22.1 0.0 0.0065 17.0 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin domain PorA PF11271.8 RJW63855.1 - 0.0026 17.1 0.3 0.0042 16.4 0.3 1.3 1 0 0 1 1 1 1 Porin PorA ig PF00047.25 RJW63855.1 - 0.081 13.1 0.0 1.6 8.9 0.0 2.7 3 2 0 3 3 3 0 Immunoglobulin domain Asp PF00026.23 RJW63856.1 - 6.4e-33 114.5 0.0 7.7e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW63856.1 - 7.8e-05 23.0 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal RelA_SpoT PF04607.17 RJW63857.1 - 0.0017 18.6 0.0 0.0087 16.3 0.0 2.3 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins CCDC74_C PF14917.6 RJW63857.1 - 0.023 15.2 0.3 0.17 12.4 0.3 2.6 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal dsDNA_bind PF01984.20 RJW63857.1 - 2.4 8.5 9.1 1.2 9.5 5.2 2.6 2 0 0 2 2 2 0 Double-stranded DNA-binding domain RA PF00788.23 RJW63858.1 - 1.7e-17 63.8 0.0 1.2e-09 38.7 0.0 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 RJW63858.1 - 0.0098 16.2 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain RRM_1 PF00076.22 RJW63859.1 - 3.9e-19 68.3 0.0 8.5e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C2 PF00648.21 RJW63861.1 - 1.6e-59 201.4 0.0 1.9e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease zf-C2H2_4 PF13894.6 RJW63862.1 - 3e-10 40.0 47.0 0.0016 19.1 0.4 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW63862.1 - 1.8e-08 34.5 38.2 2.5e-05 24.5 1.3 6.7 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 RJW63862.1 - 3.6e-05 24.0 3.7 0.0012 19.2 0.4 6.7 7 0 0 7 7 7 3 Zinc finger, C2H2 type Spt46 PF17734.1 RJW63862.1 - 0.011 15.6 4.4 0.011 15.6 4.4 2.3 2 1 2 4 4 4 0 Spermatogenesis-associated protein 46 zf-BED PF02892.15 RJW63862.1 - 0.026 14.5 2.2 0.026 14.5 2.2 3.5 3 1 1 4 4 4 0 BED zinc finger zf-C2H2_jaz PF12171.8 RJW63862.1 - 0.046 14.0 0.1 0.046 14.0 0.1 5.9 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 RJW63862.1 - 0.37 10.4 12.3 2.9 7.6 0.0 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Glyco_hydro_cc PF11790.8 RJW63863.1 - 0.19 11.2 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core rve PF00665.26 RJW63864.1 - 1.3e-17 64.0 0.0 3.8e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW63864.1 - 4.4e-12 45.9 0.1 1.1e-11 44.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 RJW63864.1 - 0.003 17.3 0.1 0.031 14.0 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain E1_DerP2_DerF2 PF02221.15 RJW63865.1 - 1.8e-14 54.3 0.7 3.1e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 ML domain DUF1935 PF09149.10 RJW63865.1 - 0.0073 16.7 0.1 0.73 10.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1935) SMP_LBD PF17047.5 RJW63865.1 - 0.067 12.7 0.1 8.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain LicD PF04991.13 RJW63867.1 - 0.00057 20.1 0.1 0.0024 18.1 0.0 1.9 2 0 0 2 2 2 1 LicD family Podoplanin PF05808.11 RJW63868.1 - 0.00027 21.1 3.8 0.00047 20.3 3.8 1.4 1 1 0 1 1 1 1 Podoplanin LRRC37AB_C PF14914.6 RJW63868.1 - 0.011 15.7 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Renin_r PF07850.14 RJW63868.1 - 0.032 14.8 0.0 0.13 12.9 0.0 1.9 2 0 0 2 2 2 0 Renin receptor-like protein DUF4448 PF14610.6 RJW63868.1 - 0.068 12.9 0.8 0.17 11.6 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 RJW63868.1 - 0.1 12.5 4.5 0.25 11.2 4.5 1.8 1 1 0 1 1 1 0 TMEM154 protein family Zip PF02535.22 RJW63868.1 - 0.66 9.1 13.3 17 4.5 13.3 2.1 1 1 0 1 1 1 0 ZIP Zinc transporter DUF4366 PF14283.6 RJW63868.1 - 0.82 9.7 5.2 0.3 11.1 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) GREB1 PF15782.5 RJW63868.1 - 3.4 4.6 7.8 4.2 4.4 7.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 RJW63869.1 - 3.9e-37 128.1 0.0 4.7e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63869.1 - 4e-09 36.2 0.0 9.2e-09 35.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW63869.1 - 3.1e-08 33.3 0.0 4.2e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RJW63869.1 - 0.00098 18.5 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RJW63869.1 - 0.0033 17.0 0.0 0.029 14.0 0.1 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 RJW63869.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family EcKinase PF02958.20 RJW63869.1 - 0.049 12.9 0.0 0.083 12.2 0.0 1.3 1 1 0 1 1 1 0 Ecdysteroid kinase PDEase_I PF00233.19 RJW63870.1 - 1.3e-78 264.0 1.1 2.1e-78 263.3 1.1 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 RJW63870.1 - 0.022 15.0 0.2 0.045 14.0 0.2 1.5 1 0 0 1 1 1 0 HD domain HTH_21 PF13276.6 RJW63871.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain VHL PF01847.16 RJW63872.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 VHL beta domain TMF_DNA_bd PF12329.8 RJW63873.1 - 0.0001 22.3 6.4 0.0001 22.3 6.4 8.2 6 3 2 9 9 9 3 TATA element modulatory factor 1 DNA binding DSX_dimer PF08828.10 RJW63873.1 - 2.8 7.7 5.5 4.3 7.1 0.2 3.4 3 0 0 3 3 3 0 Doublesex dimerisation domain DUF2935 PF11155.8 RJW63873.1 - 9 6.7 15.1 12 6.2 3.1 5.0 2 2 2 4 4 4 0 Domain of unknown function (DUF2935) FA_desaturase PF00487.24 RJW63874.1 - 0.31 10.8 6.6 0.39 10.5 6.6 1.2 1 0 0 1 1 1 0 Fatty acid desaturase 7TM_GPCR_Srsx PF10320.9 RJW63874.1 - 1.7 7.9 16.9 0.024 14.0 5.8 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx Tetraspanin PF00335.20 RJW63874.1 - 2 8.1 11.8 2.4 7.8 11.8 1.1 1 0 0 1 1 1 0 Tetraspanin family PAS_11 PF14598.6 RJW63875.1 - 3.5e-14 52.9 0.1 8.4e-10 38.8 0.0 2.9 2 0 0 2 2 2 2 PAS domain HLH PF00010.26 RJW63875.1 - 4.2e-12 45.8 0.9 7.3e-12 45.1 0.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 RJW63875.1 - 1e-08 35.2 0.0 0.00076 19.5 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 RJW63875.1 - 1.5e-06 28.4 0.0 0.046 14.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 RJW63875.1 - 7.4e-06 26.2 0.0 0.17 12.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 RJW63875.1 - 3.4e-05 24.1 0.0 0.0026 18.0 0.0 2.5 2 0 0 2 2 2 1 PAS fold LIM PF00412.22 RJW63876.1 - 9.6e-12 44.9 29.3 9.6e-08 32.1 5.6 3.3 3 1 0 3 3 3 2 LIM domain DUF4113 PF13438.6 RJW63876.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) Jas PF16135.5 RJW63876.1 - 0.13 12.5 18.0 2.9 8.2 0.2 3.4 3 0 0 3 3 3 0 TPL-binding domain in jasmonate signalling Xpo1 PF08389.12 RJW63878.1 - 1.9e-07 31.3 18.3 1.4e-05 25.2 2.6 4.5 6 0 0 6 6 6 2 Exportin 1-like protein zf-C2H2_4 PF13894.6 RJW63880.1 - 0.00022 21.8 51.2 1.4 10.0 0.3 9.1 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW63880.1 - 0.0014 18.9 12.5 1.5 9.2 0.2 5.6 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RJW63880.1 - 0.0014 18.9 5.6 0.0014 18.9 5.6 5.7 5 1 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 RJW63880.1 - 0.0023 18.3 6.7 0.0077 16.6 1.5 7.5 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-met PF12874.7 RJW63880.1 - 0.022 15.1 27.7 0.21 12.0 0.3 5.6 6 0 0 6 6 6 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 RJW63880.1 - 1.9 8.5 6.0 2 8.4 0.1 3.6 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain RNA_pol_Rpc82 PF05645.13 RJW63881.1 - 0.042 13.6 1.5 0.16 11.7 0.0 2.4 2 1 1 3 3 3 0 RNA polymerase III subunit RPC82 FapA PF03961.13 RJW63881.1 - 0.047 12.3 3.2 0.064 11.9 3.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4884 PF16225.5 RJW63881.1 - 0.072 13.2 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) CAMSAP_CC1 PF17095.5 RJW63881.1 - 0.095 12.6 3.3 0.21 11.5 3.3 1.5 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Exonuc_VII_L PF02601.15 RJW63881.1 - 0.16 11.5 4.8 0.24 11.0 4.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit vATP-synt_E PF01991.18 RJW63881.1 - 0.35 10.2 5.7 0.72 9.2 5.7 1.5 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Tubulin PF00091.25 RJW63882.1 - 5.1e-65 219.4 0.0 7.5e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW63882.1 - 2e-49 167.0 0.0 3.5e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW63882.1 - 0.0017 18.0 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain SEA PF01390.20 RJW63883.1 - 0.041 14.0 3.2 1.2 9.2 0.0 3.7 4 0 0 4 4 4 0 SEA domain NTP_transferase PF00483.23 RJW63884.1 - 7.3e-46 156.7 0.0 1e-45 156.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 RJW63884.1 - 9.2e-10 37.9 4.8 7.3e-07 28.7 0.4 3.4 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 RJW63884.1 - 5.1e-09 36.7 0.0 7.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 RJW63884.1 - 0.0036 17.0 1.5 1.4 8.7 0.2 3.3 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 RJW63884.1 - 0.045 11.9 0.0 0.064 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 RJW63884.1 - 0.047 12.6 0.3 0.15 11.0 0.4 1.7 1 1 0 1 1 1 0 L-fucokinase DUF1759 PF03564.15 RJW63885.1 - 4.9e-12 46.0 0.0 6.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Transferrin PF00405.17 RJW63885.1 - 0.0014 17.9 0.0 0.0014 17.9 0.0 1.1 1 0 0 1 1 1 1 Transferrin HAD PF12710.7 RJW63885.1 - 0.013 15.9 0.1 0.029 14.8 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RasGEF PF00617.19 RJW63888.1 - 2.1e-28 99.7 0.1 7.4e-28 97.9 0.1 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RJW63888.1 - 4.8e-19 68.5 0.2 1.5e-18 67.0 0.2 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif DEAD PF00270.29 RJW63889.1 - 4e-38 130.9 0.0 8.7e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW63889.1 - 9.6e-25 87.1 0.3 4.2e-24 85.0 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW63889.1 - 1.1e-05 25.5 0.0 3.5e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RJW63889.1 - 0.0073 16.7 0.1 0.022 15.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RJW63889.1 - 0.027 14.7 0.2 0.76 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF5389 PF17364.2 RJW63890.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5389) DUF4205 PF13898.6 RJW63892.1 - 2.6e-44 151.6 0.0 1.5e-37 129.4 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) AAA_21 PF13304.6 RJW63893.1 - 6.4e-06 26.2 0.2 8.4e-06 25.8 0.2 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 RJW63893.1 - 7e-05 23.4 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter KapB PF08810.10 RJW63893.1 - 0.016 15.3 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Kinase associated protein B SMC_N PF02463.19 RJW63893.1 - 0.027 13.9 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Cu PF17563.2 RJW63893.1 - 0.064 13.5 0.3 0.9 9.8 0.4 2.2 2 0 0 2 2 2 0 Cupiennin ParA PF10609.9 RJW63895.1 - 1.4e-80 270.3 0.0 1.7e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RJW63895.1 - 0.00016 21.7 0.0 0.0029 17.7 0.0 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 RJW63895.1 - 0.017 14.5 0.0 0.05 13.1 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1610 PF07754.11 RJW63895.1 - 0.11 12.4 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DUF4817 PF16087.5 RJW63897.1 - 3.2e-17 62.1 0.1 3.6e-16 58.7 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain (DUF4817) Phage_antitermQ PF06530.12 RJW63897.1 - 0.13 12.2 0.0 2.3 8.2 0.0 2.3 1 1 1 2 2 2 0 Phage antitermination protein Q Sema PF01403.19 RJW63898.1 - 5.1e-18 65.1 0.0 1.7e-17 63.4 0.0 1.6 1 1 0 1 1 1 1 Sema domain TSP_1 PF00090.19 RJW63901.1 - 9.8e-05 22.5 9.7 9.8e-05 22.5 9.7 2.6 2 0 0 2 2 2 1 Thrombospondin type 1 domain EGF_2 PF07974.13 RJW63901.1 - 0.026 14.9 6.2 0.026 14.9 6.2 5.6 5 2 0 5 5 5 0 EGF-like domain hEGF PF12661.7 RJW63901.1 - 0.28 11.9 27.0 2 9.2 1.8 6.3 5 0 0 5 5 5 0 Human growth factor-like EGF Pkinase PF00069.25 RJW63902.1 - 5.8e-48 163.5 0.3 1.1e-47 162.6 0.3 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW63902.1 - 4.1e-22 78.7 0.0 7.9e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 RJW63902.1 - 0.013 14.5 0.2 0.021 13.8 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 RJW63902.1 - 0.04 13.8 0.1 0.93 9.4 0.0 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family RIO1 PF01163.22 RJW63902.1 - 0.081 12.5 0.1 0.081 12.5 0.1 2.8 2 2 0 2 2 2 0 RIO1 family zf-H2C2_5 PF13909.6 RJW63904.1 - 0.00041 20.0 0.6 0.00041 20.0 0.6 2.8 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RJW63904.1 - 0.0023 18.3 0.7 0.0023 18.3 0.7 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 RJW63904.1 - 0.0027 18.4 5.0 2.8 8.6 5.0 2.6 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 RJW63904.1 - 0.012 16.4 16.6 1.7 9.7 1.5 4.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW63904.1 - 0.023 15.1 16.1 0.16 12.4 0.4 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 RJW63904.1 - 0.32 11.4 12.3 1.9 8.9 0.3 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 RJW63904.1 - 0.36 10.6 4.2 7.9 6.3 0.1 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type OST-HTH PF12872.7 RJW63905.1 - 1.7e-51 171.9 1.1 3.1e-13 49.4 0.0 7.4 7 0 0 7 7 7 5 OST-HTH/LOTUS domain RRM_1 PF00076.22 RJW63905.1 - 0.2 11.5 0.0 0.49 10.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TTL PF03133.15 RJW63907.1 - 7.8e-103 343.7 0.0 9.9e-103 343.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RJW63907.1 - 5.5e-05 22.5 0.0 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RJW63907.1 - 0.0019 17.5 0.0 0.0051 16.1 0.0 1.6 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp V-SNARE_C PF12352.8 RJW63910.1 - 1.2e-14 54.4 5.3 1.8e-14 53.7 5.3 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RJW63910.1 - 0.0043 16.9 0.7 0.0075 16.2 0.7 1.4 1 1 0 1 1 1 1 Sec20 OppC_N PF12911.7 RJW63910.1 - 0.013 15.5 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Fusion_gly PF00523.18 RJW63910.1 - 0.02 13.2 0.1 0.024 12.9 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Choline_transpo PF04515.12 RJW63910.1 - 0.16 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter DUF3958 PF13125.6 RJW63910.1 - 0.19 11.9 5.7 0.42 10.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) MBT PF02820.18 RJW63911.1 - 3.4e-71 235.6 0.1 3.4e-23 81.8 0.0 3.3 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.18 RJW63911.1 - 5.7e-12 45.6 11.2 1.5e-11 44.3 5.8 3.0 2 0 0 2 2 2 1 Zinc finger, C2HC type BTB PF00651.31 RJW63912.1 - 1.8e-26 92.5 0.3 4.2e-26 91.4 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RJW63912.1 - 3.8e-24 84.7 0.0 8.2e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 RJW63912.1 - 2.8e-22 78.0 8.0 5.7e-06 25.8 0.4 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RJW63912.1 - 1.2e-10 41.4 5.7 0.013 15.8 0.0 6.1 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW63912.1 - 1e-09 38.2 3.0 2.7e-05 24.0 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 RJW63912.1 - 2.3e-09 37.2 11.6 0.07 13.5 0.1 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 RJW63912.1 - 7.4e-07 29.1 9.5 0.053 13.5 0.0 5.9 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 RJW63912.1 - 0.00029 20.7 4.8 0.95 9.5 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Exo_endo_phos PF03372.23 RJW63913.1 - 1.1e-06 28.3 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RJW63913.1 - 0.0032 17.3 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TRH PF05438.12 RJW63913.1 - 0.072 12.8 0.6 0.12 12.1 0.6 1.3 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) CAP PF00188.26 RJW63914.1 - 1.1e-13 52.1 7.6 5.4e-13 49.9 7.6 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family TMF_DNA_bd PF12329.8 RJW63915.1 - 0.012 15.5 16.9 0.012 15.5 16.9 9.9 5 2 5 10 10 10 0 TATA element modulatory factor 1 DNA binding DUF4019 PF13211.6 RJW63915.1 - 1.6 9.2 4.9 20 5.7 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4019) MULE PF10551.9 RJW63916.1 - 4.4e-10 39.9 1.6 4.7e-10 39.8 0.2 1.8 2 0 0 2 2 2 1 MULE transposase domain DASH_Duo1 PF08651.10 RJW63916.1 - 0.071 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 Adaptin_N PF01602.20 RJW63917.1 - 6.2e-73 246.1 0.2 8.1e-73 245.8 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 RJW63917.1 - 3.9e-25 88.3 0.3 7.4e-25 87.4 0.3 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Kinetochor_Ybp2 PF08568.10 RJW63917.1 - 0.011 14.3 0.0 0.023 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin HEAT_2 PF13646.6 RJW63917.1 - 0.13 12.6 1.2 4.8 7.6 0.0 3.5 3 1 1 4 4 4 0 HEAT repeats Galactosyl_T PF01762.21 RJW63921.1 - 6.3e-20 71.8 0.0 8.4e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 RJW63921.1 - 0.035 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Fringe-like zinc_ribbon_6 PF14599.6 RJW63922.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-ribbon Lactamase_B PF00753.27 RJW63923.1 - 1.6e-15 57.6 1.7 1.4e-14 54.5 1.0 1.9 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RJW63923.1 - 6.6e-07 29.0 0.2 8.6e-07 28.7 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 RJW63923.1 - 0.00048 19.6 0.0 0.00084 18.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RJW63923.1 - 0.028 14.3 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DnaJ PF00226.31 RJW63924.1 - 1.5e-16 60.3 0.7 3.6e-16 59.0 0.7 1.7 1 0 0 1 1 1 1 DnaJ domain SF3a60_bindingd PF12108.8 RJW63924.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Pro_isomerase PF00160.21 RJW63925.1 - 3.1e-39 134.8 0.0 4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ig_3 PF13927.6 RJW63927.1 - 1.3e-52 176.3 2.6 9.7e-12 45.3 0.0 7.4 7 1 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 RJW63927.1 - 3.6e-46 155.2 0.0 8.8e-11 41.7 0.0 7.7 7 1 0 7 7 7 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW63927.1 - 1.9e-36 124.2 0.1 2.8e-06 27.6 0.0 7.6 7 1 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 RJW63927.1 - 1.5e-34 118.0 0.0 4.2e-07 30.1 0.0 7.0 6 0 0 6 6 6 5 Immunoglobulin domain fn3 PF00041.21 RJW63927.1 - 8e-31 106.2 0.3 1e-07 32.2 0.1 4.9 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 RJW63927.1 - 7.9e-20 71.1 0.3 0.0062 16.7 0.0 8.2 6 4 1 7 7 7 4 Immunoglobulin V-set domain Ig_6 PF18452.1 RJW63927.1 - 4.5e-07 29.3 0.0 0.57 9.8 0.0 5.0 5 0 0 5 5 5 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RJW63927.1 - 1.5e-05 25.4 0.3 0.2 12.3 0.1 3.9 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 RJW63927.1 - 0.0076 16.3 0.0 1.1 9.4 0.0 3.9 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 RJW63927.1 - 0.015 15.3 1.0 4.6 7.3 0.0 4.5 5 0 0 5 5 5 0 C17orf99 Ig domain Ribosomal_S6 PF01250.17 RJW63930.1 - 2.5e-15 56.5 0.0 3.3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Tudor_3 PF18115.1 RJW63931.1 - 9.8e-05 22.1 0.0 0.00029 20.6 0.0 1.9 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 RJW63931.1 - 0.0038 16.9 0.0 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 TPR_19 PF14559.6 RJW63931.1 - 0.14 12.6 0.6 0.3 11.6 0.6 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat gag-asp_proteas PF13975.6 RJW63932.1 - 0.00012 22.5 0.0 0.00026 21.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RJW63932.1 - 0.0005 20.6 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease ExoD PF06055.12 RJW63932.1 - 0.029 13.8 0.1 0.061 12.7 0.1 1.5 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD zf-CCHC_4 PF14392.6 RJW63932.1 - 0.33 10.7 3.8 0.78 9.5 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle TrkA_TMD PF18613.1 RJW63932.1 - 1.5 8.3 4.0 3.8 7.0 4.0 1.7 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain Exo_endo_phos PF03372.23 RJW63933.1 - 2.6e-05 23.9 0.0 5.9e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SAM_1 PF00536.30 RJW63935.1 - 6.1e-10 39.4 0.0 9.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RJW63935.1 - 2.1e-06 27.7 0.0 1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) AT_hook PF02178.19 RJW63935.1 - 0.0046 16.7 2.5 0.013 15.3 2.5 1.8 1 0 0 1 1 1 1 AT hook motif SAM_3 PF18016.1 RJW63935.1 - 0.2 11.5 0.1 0.4 10.5 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Tuberin PF03542.16 RJW63936.1 - 0.043 12.9 0.2 0.071 12.2 0.2 1.3 1 0 0 1 1 1 0 Tuberin Mito_carr PF00153.27 RJW63937.1 - 1.5e-63 210.7 4.1 1.9e-24 85.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 RJW63939.1 - 3.2e-55 187.5 36.9 6.3e-54 183.2 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RJW63939.1 - 1.1e-10 41.0 3.6 1.1e-10 41.0 3.6 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter GAS PF13851.6 RJW63940.1 - 1.1e-75 253.5 28.4 1.7e-75 252.8 28.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 RJW63940.1 - 0.00057 20.2 18.8 0.00057 20.2 18.8 2.3 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 RJW63940.1 - 0.0054 16.1 12.6 0.0054 16.1 12.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Metal_resist PF13801.6 RJW63940.1 - 0.027 14.7 0.4 0.027 14.7 0.4 2.6 3 1 0 3 3 2 0 Heavy-metal resistance Virulence_fact PF13769.6 RJW63940.1 - 0.027 14.7 0.5 0.027 14.7 0.5 2.1 2 1 0 2 2 2 0 Virulence factor DUF4164 PF13747.6 RJW63940.1 - 0.038 14.3 18.5 0.68 10.2 1.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) HEPN_RES_NTD1 PF18870.1 RJW63940.1 - 0.075 13.2 2.4 0.16 12.1 1.2 2.0 1 1 1 2 2 2 0 HEPN/RES N-terminal domain 1 Baculo_PEP_C PF04513.12 RJW63940.1 - 0.26 11.3 11.5 1.9 8.5 1.3 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 RJW63940.1 - 0.53 10.8 29.1 2.2 8.8 15.2 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4201 PF13870.6 RJW63940.1 - 1.5 8.5 29.1 2.2 8.0 19.7 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4201) PI3K_P85_iSH2 PF16454.5 RJW63940.1 - 1.6 8.3 23.4 0.29 10.7 2.1 3.3 1 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain bZIP_Maf PF03131.17 RJW63940.1 - 2.5 8.7 17.3 2.1 8.9 4.6 3.4 3 1 1 4 4 3 0 bZIP Maf transcription factor Nsp1_C PF05064.13 RJW63940.1 - 5.6 6.8 15.8 0.57 10.0 5.7 3.1 1 1 2 3 3 3 0 Nsp1-like C-terminal region Bap31_Bap29_C PF18035.1 RJW63940.1 - 5.8 7.0 11.1 3.3 7.8 7.7 2.4 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain ADIP PF11559.8 RJW63940.1 - 6.9 6.7 25.9 0.56 10.3 15.7 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 RJW63940.1 - 8.4 7.1 22.5 0.22 12.2 7.9 2.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Macoilin PF09726.9 RJW63940.1 - 9.2 4.7 24.3 21 3.5 3.8 1.8 1 1 1 2 2 2 0 Macoilin family Golgin_A5 PF09787.9 RJW63942.1 - 0.012 15.1 31.0 0.19 11.2 9.7 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 CENP-H PF05837.12 RJW63942.1 - 0.017 15.6 26.5 0.34 11.3 10.5 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) PI_PP_I PF18363.1 RJW63942.1 - 0.028 14.6 4.4 0.11 12.6 1.9 2.9 1 1 2 3 3 3 0 Phosphoinositide phosphatase insertion domain YgaB PF14182.6 RJW63942.1 - 0.041 14.3 2.4 0.041 14.3 2.4 3.5 1 1 2 3 3 3 0 YgaB-like protein DUF3450 PF11932.8 RJW63942.1 - 0.1 11.9 27.8 0.38 10.0 5.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Fungal_TACC PF12709.7 RJW63942.1 - 0.13 12.8 0.2 0.13 12.8 0.2 4.5 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 RJW63942.1 - 0.2 10.5 31.5 0.24 10.3 8.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 RJW63942.1 - 0.25 11.9 22.6 0.94 10.1 13.1 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal T2SSG PF08334.11 RJW63942.1 - 0.26 11.4 1.8 0.68 10.0 0.1 2.3 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein G DUF1664 PF07889.12 RJW63942.1 - 0.27 11.3 13.3 1 9.4 3.5 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 RJW63942.1 - 0.28 11.2 26.1 0.11 12.5 5.4 4.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.9 RJW63942.1 - 0.36 11.1 35.1 0.11 12.7 7.7 2.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 SOAR PF16533.5 RJW63942.1 - 0.62 10.1 15.6 0.036 14.1 2.5 2.8 2 1 1 3 3 3 0 STIM1 Orai1-activating region ComP_DUS PF16732.5 RJW63942.1 - 0.63 11.0 6.6 4.9 8.1 0.4 2.6 2 1 0 2 2 2 0 Type IV minor pilin ComP, DNA uptake sequence receptor NPV_P10 PF05531.12 RJW63942.1 - 0.64 10.5 9.3 9.8 6.7 0.3 3.5 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.21 RJW63942.1 - 0.77 9.9 24.9 1.1 9.5 0.9 4.8 4 1 1 5 5 5 0 bZIP transcription factor DUF5344 PF17279.2 RJW63942.1 - 0.81 10.3 12.4 1.5 9.4 0.7 3.5 3 1 1 4 4 3 0 Family of unknown function (DUF5344) TPR_MLP1_2 PF07926.12 RJW63942.1 - 0.85 9.7 31.6 2 8.5 11.9 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Prominin PF05478.11 RJW63942.1 - 0.97 7.3 13.4 0.39 8.6 6.3 2.6 1 1 2 3 3 3 0 Prominin FUSC PF04632.12 RJW63942.1 - 1.4 7.4 20.1 9.5 4.6 20.1 2.1 1 1 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 RJW63942.1 - 2.1 8.8 30.1 3.2e+02 1.6 29.9 2.8 1 1 0 1 1 1 0 Fez1 DUF3584 PF12128.8 RJW63942.1 - 3.3 5.1 28.1 6.6 4.1 28.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 RJW63942.1 - 4.1 7.6 16.8 2.4 8.4 3.4 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family PIN PF01850.21 RJW63942.1 - 4.2 7.9 9.5 12 6.5 0.7 2.7 1 1 2 3 3 3 0 PIN domain TMPIT PF07851.13 RJW63942.1 - 5 6.3 17.4 0.32 10.2 6.6 2.2 1 1 1 2 2 2 0 TMPIT-like protein GAS PF13851.6 RJW63942.1 - 7.3 5.9 30.6 0.17 11.2 7.3 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding LppA PF16708.5 RJW63942.1 - 7.9 6.4 8.4 25 4.8 2.9 2.7 2 1 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium DUF4407 PF14362.6 RJW63942.1 - 8.8 5.6 23.2 6.9e+02 -0.6 23.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sec34 PF04136.15 RJW63942.1 - 9.2 6.1 15.2 3.2 7.6 4.3 3.0 1 1 1 3 3 3 0 Sec34-like family MscS_porin PF12795.7 RJW63942.1 - 9.7 5.7 35.8 2.3 7.7 16.4 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain EF-hand_1 PF00036.32 RJW63943.1 - 7.4e-29 97.1 13.4 3.6e-06 26.2 1.1 6.6 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 RJW63943.1 - 1.5e-22 77.5 17.2 3.5e-05 23.4 0.9 6.5 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.6 RJW63943.1 - 7e-21 72.7 17.0 0.00086 18.7 0.1 6.4 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 RJW63943.1 - 1.4e-19 70.3 19.8 2.5e-08 34.2 2.7 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 RJW63943.1 - 1.4e-09 37.6 17.7 0.0098 15.7 0.4 6.0 5 2 1 6 6 6 5 EF-hand domain pair Dockerin_1 PF00404.18 RJW63943.1 - 0.0034 17.5 4.6 0.67 10.2 0.1 3.7 4 0 0 4 4 4 1 Dockerin type I domain Put_Phosphatase PF06888.12 RJW63943.1 - 0.036 13.5 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative Phosphatase EF-hand_10 PF14788.6 RJW63943.1 - 0.04 13.8 7.4 9.9 6.1 0.1 4.6 5 0 0 5 5 5 0 EF hand SPARC_Ca_bdg PF10591.9 RJW63943.1 - 9.7 6.5 10.3 50 4.2 0.1 4.6 3 1 2 5 5 5 0 Secreted protein acidic and rich in cysteine Ca binding region HLH PF00010.26 RJW63945.1 - 2.4e-15 56.2 1.7 4.3e-15 55.4 1.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TRAM PF01938.20 RJW63946.1 - 2.2e-06 27.5 0.0 4.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 TRAM domain Glyco_hydro_38N PF01074.22 RJW63948.1 - 2.2e-85 286.5 1.9 3.3e-85 285.9 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain RVT_1 PF00078.27 RJW63948.1 - 6.6e-45 153.3 0.0 1.2e-44 152.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_38C PF07748.13 RJW63948.1 - 8.6e-28 97.9 0.0 1.7e-27 96.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 RJW63948.1 - 9.8e-19 67.3 0.8 3e-18 65.8 0.1 2.3 2 0 0 2 2 2 1 Alpha mannosidase middle domain Carn_acyltransf PF00755.20 RJW63949.1 - 1.1e-24 87.1 0.0 1.6e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RVT_1 PF00078.27 RJW63949.1 - 1.1e-07 31.6 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phos_pyr_kin PF08543.12 RJW63950.1 - 4.1e-10 39.5 0.0 5.6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 RJW63950.1 - 2.7e-06 26.9 0.0 1.1e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase G-gamma PF00631.22 RJW63951.1 - 1.4e-14 53.8 0.1 1.7e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 GGL domain RHH_1 PF01402.21 RJW63951.1 - 0.028 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Ank_2 PF12796.7 RJW63953.1 - 8.4e-38 128.8 11.6 1.5e-13 51.2 0.0 4.2 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW63953.1 - 4.4e-27 91.2 6.9 1.1e-05 25.4 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 RJW63953.1 - 6.9e-25 86.8 10.1 4.2e-07 30.1 0.0 5.7 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RJW63953.1 - 8.7e-25 86.0 11.7 2.6e-06 27.6 0.0 7.2 5 2 2 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 RJW63953.1 - 1.6e-24 85.9 9.5 5.7e-11 42.7 0.2 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Dynein_light PF01221.18 RJW63955.1 - 2.5e-14 53.4 0.0 3.4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Cloacin PF03515.14 RJW63955.1 - 0.22 11.2 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain ECH_1 PF00378.20 RJW63956.1 - 2.9e-68 229.9 0.3 4.5e-68 229.3 0.3 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RJW63956.1 - 2.2e-30 106.3 0.3 4e-30 105.5 0.3 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 RJW63956.1 - 0.037 14.0 0.2 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 Dynein_light PF01221.18 RJW63958.1 - 1e-17 64.2 0.0 1.8e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 ANAPC4_WD40 PF12894.7 RJW63969.1 - 6.2e-19 68.1 0.0 0.0021 18.3 0.0 5.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW63969.1 - 1.3e-13 51.2 2.6 9.8e-06 26.2 0.1 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 RJW63969.1 - 0.00021 21.2 0.0 0.024 14.5 0.0 2.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PSII_BNR PF14870.6 RJW63969.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 IKI3 PF04762.12 RJW63969.1 - 0.19 9.7 0.0 1 7.2 0.0 2.0 2 1 1 3 3 3 0 IKI3 family Carn_acyltransf PF00755.20 RJW63970.1 - 1.9e-39 135.8 0.0 2.5e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MORN PF02493.20 RJW63971.1 - 8.8e-23 78.8 27.6 5.5e-05 22.8 3.5 7.8 7 1 0 7 7 7 6 MORN repeat Tektin PF03148.14 RJW63973.1 - 7.4e-76 255.4 24.9 8.3e-76 255.2 24.9 1.0 1 0 0 1 1 1 1 Tektin family Phos_pyr_kin PF08543.12 RJW63973.1 - 0.11 11.9 0.4 0.22 10.8 0.4 1.5 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF4650 PF15509.6 RJW63973.1 - 0.15 11.4 2.5 0.19 11.0 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) Retrotrans_gag PF03732.17 RJW63973.1 - 0.19 12.0 5.0 0.42 10.9 0.5 2.9 2 1 0 2 2 2 0 Retrotransposon gag protein T3SS_needle_E PF08988.10 RJW63973.1 - 1.7 8.9 14.3 2 8.6 1.4 4.2 3 1 3 6 6 6 0 Type III secretion system, cytoplasmic E component of needle Syntaxin-6_N PF09177.11 RJW63973.1 - 7.6 7.2 16.4 6.9 7.3 1.0 3.5 2 2 2 4 4 4 0 Syntaxin 6, N-terminal Sec2p PF06428.11 RJW63973.1 - 8.4 6.4 17.0 2.2 8.3 6.1 3.7 2 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p CC2-LZ PF16516.5 RJW63973.1 - 8.6 6.8 17.5 0.45 10.9 0.8 4.0 3 1 1 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator RVT_1 PF00078.27 RJW63974.1 - 5.8e-10 39.1 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Macoilin PF09726.9 RJW63974.1 - 3.1 6.2 5.6 4.6 5.7 5.6 1.2 1 0 0 1 1 1 0 Macoilin family DUF4661 PF15576.6 RJW63974.1 - 4.5 7.1 8.5 9.4 6.1 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Forkhead PF00250.18 RJW63976.1 - 6.8e-25 87.2 0.1 1.5e-24 86.1 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Glyco_hydro_38N PF01074.22 RJW63978.1 - 1.9e-67 227.6 0.2 3.2e-67 226.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 RJW63978.1 - 3.2e-24 84.9 0.0 6.4e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 RJW63978.1 - 1.3e-15 58.1 0.0 3e-15 56.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38N PF01074.22 RJW63979.1 - 8.2e-71 238.7 2.8 1.1e-70 238.2 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 RJW63979.1 - 1.7e-22 80.5 0.0 3.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 RJW63979.1 - 5.3e-20 71.4 0.0 1.4e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Tachystatin_A PF11406.8 RJW63980.1 - 0.076 13.1 0.2 0.19 11.8 0.2 1.7 1 1 1 2 2 2 0 Antimicrobial peptide tachystatin A UPF0004 PF00919.20 RJW63981.1 - 8.7e-16 57.8 0.0 1.4e-06 28.3 0.0 3.4 3 0 0 3 3 3 2 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 RJW63981.1 - 4.5e-07 30.4 0.0 9.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily T2SSC PF11356.8 RJW63983.1 - 0.021 14.7 0.6 0.027 14.4 0.6 1.2 1 0 0 1 1 1 0 Type II secretion system protein C DUF2090 PF09863.9 RJW63983.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) GAIN_A PF18619.1 RJW63983.1 - 0.26 11.5 3.7 4.3 7.6 0.2 2.5 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Tubulin PF00091.25 RJW63984.1 - 1.2e-60 205.1 0.0 1.9e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW63984.1 - 1e-42 145.3 0.0 1.9e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW63984.1 - 0.031 13.9 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain Prok-RING_2 PF14445.6 RJW63985.1 - 0.027 14.6 0.2 0.027 14.6 0.2 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 zf-C2H2 PF00096.26 RJW63985.1 - 0.35 11.4 34.5 2.5 8.7 0.6 5.5 4 1 1 5 5 5 0 Zinc finger, C2H2 type MFS_1 PF07690.16 RJW63986.1 - 4.6e-27 94.9 8.7 5.9e-26 91.2 5.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Laminin_N PF00055.17 RJW63988.1 - 2.5e-41 141.8 7.4 7.9e-40 136.9 0.7 3.2 3 1 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 RJW63988.1 - 3.1e-07 30.4 13.8 3.1e-07 30.4 13.8 2.4 2 0 0 2 2 2 1 Laminin EGF domain F5_F8_type_C PF00754.25 RJW63988.1 - 0.034 14.2 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain BNR_6 PF15899.5 RJW63988.1 - 0.32 11.2 1.6 1 9.6 1.6 1.9 1 0 0 1 1 1 0 BNR-Asp box repeat M16C_assoc PF08367.11 RJW63990.1 - 9.5e-61 205.1 0.0 5.6e-60 202.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 RJW63990.1 - 4.8e-15 56.1 0.0 3e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF1957 PF09210.11 RJW63990.1 - 0.018 15.4 0.2 0.051 14.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) DUF3631 PF12307.8 RJW63990.1 - 1.7 8.9 7.8 0.86 9.8 2.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3631) Josephin PF02099.17 RJW63991.1 - 6.2e-24 84.9 0.2 5.2e-22 78.7 0.2 2.1 1 1 0 1 1 1 1 Josephin YTH PF04146.15 RJW63992.1 - 1.5e-39 135.6 0.5 1.5e-39 135.6 0.5 2.8 2 2 0 2 2 2 1 YT521-B-like domain Ebola_NP PF05505.12 RJW63992.1 - 0.73 8.1 5.0 0.97 7.7 5.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein 7tm_1 PF00001.21 RJW63993.1 - 5.4e-12 45.6 1.0 5.8e-12 45.5 1.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) AP_endonuc_2 PF01261.24 RJW63993.1 - 0.21 11.0 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Helicase_C PF00271.31 RJW63994.1 - 3e-25 88.7 0.0 1e-24 87.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RJW63994.1 - 9.3e-23 80.9 0.0 1.9e-21 76.6 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase gag-asp_proteas PF13975.6 RJW63995.1 - 1.6e-09 38.2 0.0 3.7e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RJW63995.1 - 3.4e-06 27.6 0.0 9.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Integrase_H2C2 PF17921.1 RJW63995.1 - 6.6e-05 22.9 1.3 0.00032 20.7 1.3 2.2 1 1 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 RJW63995.1 - 0.00096 18.9 0.1 0.0018 18.0 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 RJW63995.1 - 0.0047 16.5 0.1 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 Ty3 transposon peptidase RVP PF00077.20 RJW63995.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 RJW63995.1 - 0.094 12.9 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain ABC_membrane PF00664.23 RJW63997.1 - 2.3e-69 234.1 29.9 1.2e-35 123.5 10.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RJW63997.1 - 4e-54 182.9 0.0 7.4e-31 107.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RJW63997.1 - 3.2e-10 39.8 5.6 0.003 17.0 0.0 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RJW63997.1 - 3.7e-06 27.0 0.1 0.0033 17.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RJW63997.1 - 4.3e-06 26.8 0.6 0.069 13.2 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 RJW63997.1 - 6.1e-05 22.7 1.1 0.16 11.7 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 RJW63997.1 - 0.0004 20.5 3.0 0.023 14.8 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 RJW63997.1 - 0.00058 20.4 0.4 0.54 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RJW63997.1 - 0.00061 20.2 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 RJW63997.1 - 0.0043 16.9 5.9 1 9.1 1.0 3.8 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 RJW63997.1 - 0.016 15.2 1.1 0.6 10.1 0.1 2.4 2 0 0 2 2 2 0 Dynamin family DUF815 PF05673.13 RJW63997.1 - 0.018 14.2 0.1 3.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 RJW63997.1 - 0.027 14.2 0.7 13 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 RJW63997.1 - 0.03 14.6 2.8 2.2 8.5 0.1 3.2 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 RJW63997.1 - 0.07 12.8 0.2 16 5.1 1.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 RJW63997.1 - 0.11 11.8 0.2 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PCMT PF01135.19 RJW63999.1 - 1.3e-20 74.0 0.0 1e-14 54.8 0.0 2.2 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 RJW63999.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 RJW63999.1 - 0.18 11.8 0.0 0.66 9.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Lig_chan PF00060.26 RJW64000.1 - 3.3e-51 173.0 0.9 6.5e-51 172.1 0.9 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RJW64000.1 - 4.1e-36 123.7 0.0 7e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 RJW64000.1 - 6.7e-31 107.7 0.0 1.2e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 RJW64000.1 - 1.5e-21 76.9 0.0 3.8e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Cortexin PF11057.8 RJW64000.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Cortexin of kidney Peripla_BP_6 PF13458.6 RJW64000.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Ion_trans_2 PF07885.16 RJW64000.1 - 1.1 9.3 9.3 0.2 11.6 4.4 2.4 2 0 0 2 2 2 0 Ion channel Prominin PF05478.11 RJW64002.1 - 1.7e-42 145.4 5.9 3.2e-28 98.2 0.0 2.6 2 1 1 3 3 3 2 Prominin DUF2207 PF09972.9 RJW64002.1 - 0.00017 20.5 0.7 0.011 14.5 0.0 2.4 3 0 0 3 3 3 1 Predicted membrane protein (DUF2207) DNA_pol3_tau_5 PF12170.8 RJW64002.1 - 0.051 13.6 1.5 0.15 12.1 1.5 1.8 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha MutS_III PF05192.18 RJW64002.1 - 0.054 13.7 0.2 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 MutS domain III HMMR_N PF15905.5 RJW64002.1 - 0.25 10.8 7.3 0.13 11.7 1.0 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4446 PF14584.6 RJW64002.1 - 0.43 10.6 1.6 7.2 6.6 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Apolipoprotein PF01442.18 RJW64002.1 - 0.51 10.2 13.1 0.73 9.7 5.0 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 RJW64002.1 - 1.8 9.0 6.7 24 5.5 0.2 3.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Utp12 PF04003.12 RJW64002.1 - 2.2 8.6 5.0 0.54 10.6 0.8 2.2 2 0 0 2 2 2 0 Dip2/Utp12 Family DUF2408 PF10303.9 RJW64002.1 - 2.7 8.6 8.6 1.5 9.4 4.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Syntaxin_2 PF14523.6 RJW64002.1 - 3.3 8.1 7.9 2.6 8.5 2.7 2.9 2 0 0 2 2 2 0 Syntaxin-like protein FlgN PF05130.12 RJW64002.1 - 3.3 8.2 9.2 2 8.9 2.7 2.9 2 1 0 2 2 2 0 FlgN protein FancD2 PF14631.6 RJW64003.1 - 4.1e-49 167.1 4.8 1.2e-32 112.4 0.8 4.7 4 1 0 4 4 4 3 Fanconi anaemia protein FancD2 nuclease PDZ PF00595.24 RJW64004.1 - 1.6e-12 47.6 0.0 3.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW64004.1 - 4.1e-07 29.7 0.0 9.4e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW64004.1 - 0.00058 20.1 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain 7tm_1 PF00001.21 RJW64006.1 - 8.4e-29 100.7 0.9 1.4e-28 100.0 0.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW64006.1 - 0.00096 18.9 7.2 0.0019 17.9 1.8 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Mce4_CUP1 PF11887.8 RJW64007.1 - 0.055 12.9 0.1 0.061 12.8 0.1 1.0 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Ras PF00071.22 RJW64008.1 - 5.2e-24 84.7 0.0 2e-21 76.3 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RJW64008.1 - 1e-14 54.7 0.0 5e-13 49.3 0.0 2.6 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW64008.1 - 0.00045 19.7 0.0 0.0088 15.5 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW64008.1 - 0.00074 19.6 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 RJW64008.1 - 0.012 14.9 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.10 RJW64008.1 - 0.012 15.1 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit WD40 PF00400.32 RJW64010.1 - 1.3e-13 51.1 20.3 7.2e-05 23.5 1.0 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW64010.1 - 0.0045 17.3 0.1 0.48 10.8 0.0 3.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain FancD2 PF14631.6 RJW64011.1 - 4.5e-07 27.7 0.1 5.9e-07 27.4 0.1 1.1 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease SDA1 PF05285.12 RJW64011.1 - 0.047 13.1 6.5 0.053 12.9 6.5 1.0 1 0 0 1 1 1 0 SDA1 Laminin_EGF PF00053.24 RJW64012.1 - 4e-16 58.9 42.2 2.1e-09 37.4 13.4 3.3 4 0 0 4 4 4 2 Laminin EGF domain NTR PF01759.21 RJW64012.1 - 1.1e-12 47.6 0.0 1.2e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 UNC-6/NTR/C345C module Jagunal PF07086.12 RJW64014.1 - 5.5e-60 202.6 0.6 6.3e-60 202.5 0.6 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis DUF3974 PF13120.6 RJW64014.1 - 0.13 12.4 0.4 0.28 11.3 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) Lig_chan PF00060.26 RJW64015.1 - 1.6e-49 167.6 0.6 2.7e-49 166.8 0.6 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RJW64015.1 - 9.3e-37 125.7 0.1 1.6e-36 125.0 0.1 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RJW64015.1 - 1.6e-21 76.8 0.0 3.7e-21 75.6 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 RJW64015.1 - 0.0095 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Cortexin PF11057.8 RJW64015.1 - 0.01 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Cortexin of kidney Ion_trans_2 PF07885.16 RJW64015.1 - 6.2 6.9 7.5 1.1 9.2 2.5 2.3 2 0 0 2 2 2 0 Ion channel zinc_ribbon_6 PF14599.6 RJW64016.1 - 0.073 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon Ribosomal_L4 PF00573.22 RJW64018.1 - 2.4e-32 112.2 0.0 1.1e-31 110.0 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family Pkinase PF00069.25 RJW64019.1 - 1.6e-39 135.9 0.0 2.4e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64019.1 - 3.7e-28 98.5 0.0 5.4e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW64019.1 - 2.1e-05 23.5 2.8 2.7e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RJW64019.1 - 9.7e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RJW64019.1 - 0.0018 18.2 0.1 0.0044 17.0 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RFC1 PF08519.12 RJW64020.1 - 7.3e-39 133.4 0.0 3.9e-37 127.8 0.0 2.7 3 0 0 3 3 3 1 Replication factor RFC1 C terminal domain AAA PF00004.29 RJW64020.1 - 1.9e-14 54.2 0.0 4.5e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RJW64020.1 - 0.0081 15.9 0.0 0.024 14.4 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RJW64020.1 - 0.0083 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RJW64020.1 - 0.011 16.1 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RJW64020.1 - 0.013 15.9 0.0 0.045 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 RJW64020.1 - 0.02 14.8 0.1 1.8 8.4 0.0 2.6 2 1 0 2 2 2 0 Rad17 P-loop domain DNA_pol3_delta PF06144.13 RJW64020.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF4371 PF14291.6 RJW64020.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) Pkinase PF00069.25 RJW64021.1 - 3.2e-68 230.0 0.0 4.6e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64021.1 - 2.3e-39 135.3 0.0 1.6e-38 132.5 0.1 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 RJW64021.1 - 1.2e-12 48.0 0.0 5.7e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 RJW64021.1 - 3.8e-05 23.1 0.0 7.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RJW64021.1 - 0.00025 19.9 0.0 0.0005 19.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RJW64021.1 - 0.0019 17.2 0.3 0.012 14.6 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain DUF4596 PF15363.6 RJW64024.1 - 4.8 7.5 4.9 53 4.2 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) zf-CCHC_5 PF14787.6 RJW64024.1 - 5.5 6.8 7.2 45 3.9 0.4 3.9 3 2 0 3 3 3 0 GAG-polyprotein viral zinc-finger ARGLU PF15346.6 RJW64025.1 - 3.7e-26 91.8 40.1 5.3e-16 58.8 25.9 2.0 1 1 1 2 2 2 2 Arginine and glutamate-rich 1 DUF5384 PF17358.2 RJW64025.1 - 0.37 10.8 30.2 0.47 10.5 29.7 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5384) Aminotran_5 PF00266.19 RJW64027.1 - 8.8e-21 74.3 0.3 1.3e-18 67.1 0.3 2.7 1 1 0 1 1 1 1 Aminotransferase class-V GAPES4 PF17157.4 RJW64028.1 - 0.11 13.0 0.0 0.34 11.3 0.0 1.8 1 1 1 2 2 2 0 Gammaproteobacterial periplasmic sensor domain NMD3 PF04981.13 RJW64029.1 - 1.3e-49 168.9 10.4 1.9e-49 168.3 10.4 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 RJW64029.1 - 0.064 13.3 12.5 0.13 12.3 5.1 2.6 1 1 1 2 2 2 0 Double zinc ribbon NinF PF05810.12 RJW64029.1 - 0.099 12.5 3.0 0.45 10.4 2.4 2.4 2 0 0 2 2 2 0 NinF protein AAA_22 PF13401.6 RJW64031.1 - 8.3e-06 26.1 0.1 0.11 12.8 0.1 4.2 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 RJW64031.1 - 1.5e-05 25.0 0.0 0.017 15.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 RJW64031.1 - 1.8e-05 24.8 0.0 0.0093 15.9 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 RJW64031.1 - 3.7e-05 23.3 0.0 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 RJW64031.1 - 5.6e-05 23.6 0.0 0.0055 17.1 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 RJW64031.1 - 0.00018 22.0 0.1 0.22 12.0 0.1 3.2 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 RJW64031.1 - 0.00036 21.0 9.0 0.078 13.4 0.0 4.9 6 1 1 7 7 5 2 AAA ATPase domain AAA_29 PF13555.6 RJW64031.1 - 0.00052 19.7 1.9 0.79 9.5 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 RJW64031.1 - 0.00055 20.5 0.3 1.6 9.3 0.0 3.6 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 RJW64031.1 - 0.0032 17.4 0.5 2.3 8.1 0.0 3.4 4 0 0 4 4 4 1 RsgA GTPase AAA_14 PF13173.6 RJW64031.1 - 0.0039 17.2 0.0 0.28 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RJW64031.1 - 0.0066 16.6 1.7 0.14 12.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 RJW64031.1 - 0.013 15.6 0.1 0.071 13.2 0.1 2.3 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSF PF00482.23 RJW64031.1 - 0.027 14.4 2.8 0.12 12.4 0.6 3.0 3 0 0 3 3 2 0 Type II secretion system (T2SS), protein F RNA_helicase PF00910.22 RJW64031.1 - 0.029 14.8 0.0 8.1 6.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.20 RJW64031.1 - 0.045 12.9 5.6 0.83 8.7 0.0 3.1 2 2 0 3 3 3 0 G-protein alpha subunit T2SSE PF00437.20 RJW64031.1 - 0.054 12.5 0.0 0.84 8.6 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 RJW64031.1 - 0.068 13.1 0.1 17 5.3 0.0 3.6 3 0 0 3 3 2 0 NACHT domain AAA_28 PF13521.6 RJW64031.1 - 0.069 13.4 2.9 10 6.3 0.0 3.4 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 RJW64031.1 - 0.11 12.1 0.1 4.5 6.9 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 RJW64031.1 - 0.11 12.3 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 RJW64031.1 - 0.19 11.1 0.5 1.9 7.8 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 RJW64031.1 - 0.71 10.3 8.4 93 3.4 0.1 4.4 4 0 0 4 4 4 0 AAA domain Csm1_N PF18504.1 RJW64031.1 - 0.75 10.2 8.0 0.064 13.6 0.5 3.1 3 0 0 3 3 2 0 Csm1 N-terminal domain zf-Tim10_DDP PF02953.15 RJW64031.1 - 1.4 8.6 4.8 2.6 7.7 0.3 3.5 3 0 0 3 3 3 0 Tim10/DDP family zinc finger AAA PF00004.29 RJW64033.1 - 1.1e-40 139.2 0.0 2.1e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW64033.1 - 3.4e-10 39.6 0.2 6.4e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 RJW64033.1 - 4.4e-09 36.2 0.8 8.8e-09 35.2 0.8 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 RJW64033.1 - 8.8e-06 25.9 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 RJW64033.1 - 1.6e-05 24.2 0.0 2.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 RJW64033.1 - 2.9e-05 24.4 0.3 0.015 15.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 RJW64033.1 - 0.00014 22.3 0.2 0.0056 17.1 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RJW64033.1 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RJW64033.1 - 0.00081 19.4 0.5 0.007 16.4 0.5 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 RJW64033.1 - 0.00087 19.6 0.3 0.0077 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RJW64033.1 - 0.0017 18.9 0.1 0.009 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 RJW64033.1 - 0.0033 16.8 0.3 0.43 9.9 0.0 3.1 3 0 0 3 3 3 1 KaiC AAA_33 PF13671.6 RJW64033.1 - 0.01 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RJW64033.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RJW64033.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 RJW64033.1 - 0.013 15.4 0.1 0.049 13.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 RJW64033.1 - 0.031 13.9 0.3 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain TIP49 PF06068.13 RJW64033.1 - 0.044 13.0 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 RJW64033.1 - 0.047 13.5 0.2 5.3 6.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RJW64033.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 RJW64033.1 - 0.053 13.1 1.9 0.45 10.1 0.4 2.6 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 RJW64033.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 RJW64033.1 - 0.07 12.3 0.1 0.55 9.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 RJW64033.1 - 0.086 12.3 0.2 0.45 9.9 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 RJW64033.1 - 0.1 11.9 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 RJW64033.1 - 0.13 12.0 0.8 0.29 10.8 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RJW64033.1 - 0.16 11.4 0.1 0.42 10.1 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 RJW64033.1 - 0.17 11.6 0.2 0.68 9.6 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 RJW64033.1 - 0.18 11.0 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 RJW64033.1 - 0.19 11.4 0.4 0.38 10.5 0.4 1.5 1 1 0 1 1 1 0 AAA domain MT PF12777.7 RJW64036.1 - 8.6e-05 21.7 0.1 0.00016 20.8 0.1 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor BAR PF03114.18 RJW64036.1 - 0.001 18.8 7.6 0.0029 17.3 7.6 1.7 1 0 0 1 1 1 1 BAR domain AAA_16 PF13191.6 RJW64036.1 - 0.0027 18.1 0.0 0.11 12.9 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain Dynein_AAA_lid PF17852.1 RJW64036.1 - 0.0056 16.8 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain RNA_helicase PF00910.22 RJW64036.1 - 0.0081 16.5 0.0 5.3 7.5 0.0 3.0 3 0 0 3 3 3 1 RNA helicase ATPase_2 PF01637.18 RJW64036.1 - 0.017 15.0 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 RJW64036.1 - 0.021 15.3 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 RJW64036.1 - 2.9 8.3 0.0 2.9 8.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF2564 PF10819.8 RJW64036.1 - 5 7.6 9.9 3 8.3 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) T3SSipB PF16535.5 RJW64036.1 - 7.1 7.1 11.5 17 5.8 6.4 3.3 2 1 0 2 2 2 0 Type III cell invasion protein SipB zf-H2C2_2 PF13465.6 RJW64040.1 - 3e-19 68.5 35.3 5.4e-06 26.6 2.0 6.2 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 RJW64040.1 - 1.3e-16 60.0 39.0 0.001 19.4 0.3 6.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW64040.1 - 1e-12 47.7 35.2 0.0056 17.4 0.4 6.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW64040.1 - 0.0002 21.3 26.9 0.047 13.7 2.5 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW64040.1 - 0.0026 18.0 18.4 7.8 6.9 0.1 5.9 4 1 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RJW64040.1 - 0.0032 17.7 1.8 0.0032 17.7 1.8 3.9 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 RJW64040.1 - 0.01 15.6 0.8 0.01 15.6 0.8 3.7 5 0 0 5 5 4 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 RJW64040.1 - 0.037 13.9 5.8 0.29 11.0 0.1 4.1 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 RJW64040.1 - 0.051 13.5 3.2 15 5.6 0.3 3.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met PF12874.7 RJW64040.1 - 0.07 13.6 0.2 0.07 13.6 0.2 5.9 4 1 0 4 4 4 0 Zinc-finger of C2H2 type zf-met2 PF12907.7 RJW64040.1 - 0.29 11.3 6.3 0.22 11.7 0.2 3.1 1 1 1 2 2 2 0 Zinc-binding PyrI_C PF02748.15 RJW64040.1 - 1.5 8.8 5.9 2.9 7.8 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 RJW64040.1 - 2.6 8.2 18.6 4.9 7.3 4.7 4.2 2 2 2 4 4 4 0 Zinc ribbon domain zf-C2HE PF16278.5 RJW64040.1 - 3.7 8.1 14.8 6.5 7.3 3.1 4.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Ank_4 PF13637.6 RJW64041.1 - 0.022 15.3 0.0 0.034 14.7 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW64041.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) HCV_NS5a_C PF12941.7 RJW64042.1 - 0.038 13.9 2.0 0.042 13.7 2.0 1.0 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region DUF2464 PF10240.9 RJW64049.1 - 4.6e-41 141.1 0.0 6.6e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Multivesicular body subunit 12 ADAM17_MPD PF16698.5 RJW64049.1 - 0.016 15.6 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Membrane-proximal domain, switch, for ADAM17 DUF2895 PF11444.8 RJW64050.1 - 2 7.7 4.6 2.1 7.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) RVT_1 PF00078.27 RJW64052.1 - 2.9e-05 23.7 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SOCS_box PF07525.16 RJW64053.1 - 8.1e-09 35.7 2.8 1.7e-08 34.7 2.8 1.6 1 0 0 1 1 1 1 SOCS box Aminotran_1_2 PF00155.21 RJW64054.1 - 5.6e-48 163.9 0.0 7.3e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RJW64054.1 - 0.0056 16.0 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 RJW64054.1 - 0.044 12.7 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DUF1759 PF03564.15 RJW64055.1 - 0.001 19.0 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Bax1-I PF01027.20 RJW64058.1 - 7e-26 91.4 14.5 8.9e-26 91.0 14.5 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2157 PF09925.9 RJW64058.1 - 0.11 12.3 11.7 0.21 11.4 11.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Presenilin PF01080.17 RJW64058.1 - 0.91 8.2 5.0 1.2 7.8 5.0 1.2 1 0 0 1 1 1 0 Presenilin MerC PF03203.14 RJW64058.1 - 1.9 9.0 10.2 9.6 6.7 7.7 2.2 1 1 1 2 2 2 0 MerC mercury resistance protein F-box-like PF12937.7 RJW64059.1 - 0.0047 16.8 0.9 0.011 15.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RJW64059.1 - 0.0052 16.6 0.2 0.015 15.2 0.2 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 RJW64059.1 - 0.04 14.4 3.2 23 5.6 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DnaJ PF00226.31 RJW64060.1 - 3.9e-22 78.1 0.5 1.7e-21 76.1 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 RJW64060.1 - 9.1e-07 29.0 1.4 0.00077 19.6 0.1 4.0 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RJW64060.1 - 0.022 15.0 6.4 0.96 9.7 0.0 3.4 4 0 0 4 4 4 0 Myb-like DNA-binding domain Methyltransf_11 PF08241.12 RJW64061.1 - 6.5e-09 36.3 0.1 2.5e-07 31.3 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW64061.1 - 2.9e-08 34.3 0.0 3.4e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 RJW64061.1 - 5.5e-05 23.0 0.0 0.0079 16.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 RJW64061.1 - 0.00014 22.5 0.0 0.036 14.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RJW64061.1 - 0.0033 17.3 0.0 0.007 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CPSase_L_D2 PF02786.17 RJW64062.1 - 1e-77 260.4 0.2 1.7e-77 259.7 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RJW64062.1 - 1.7e-42 144.4 0.0 4.5e-42 143.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RJW64062.1 - 2.1e-33 114.6 0.0 5.5e-33 113.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 RJW64062.1 - 1.2e-08 34.8 0.1 1.7e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 RJW64062.1 - 9.9e-07 28.5 0.1 2.4e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 RJW64062.1 - 0.00033 20.7 0.0 0.00094 19.3 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Pkinase PF00069.25 RJW64065.1 - 8.4e-40 136.8 0.0 1.1e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64065.1 - 7.9e-12 45.0 0.0 2.2e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW64065.1 - 0.0081 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain SHMT PF00464.19 RJW64067.1 - 2e-173 576.6 0.0 3.1e-173 576.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF2464 PF10240.9 RJW64067.1 - 1.1e-17 64.5 0.0 6.5e-15 55.4 0.0 3.1 1 1 1 2 2 2 2 Multivesicular body subunit 12 zf-C3H1 PF10650.9 RJW64070.1 - 0.0014 18.3 2.2 0.0014 18.3 2.2 2.3 2 0 0 2 2 2 1 Putative zinc-finger domain GDI PF00996.18 RJW64072.1 - 1.9e-22 79.4 0.0 2.9e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NmrA PF05368.13 RJW64073.1 - 0.035 13.7 0.0 0.04 13.5 0.0 1.0 1 0 0 1 1 1 0 NmrA-like family NPAT_C PF15712.5 RJW64074.1 - 0.11 11.2 11.9 0.14 10.7 11.9 1.1 1 0 0 1 1 1 0 NPAT C terminus SR-25 PF10500.9 RJW64074.1 - 2.8 7.5 29.2 4.5 6.8 29.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5466 PF17554.2 RJW64074.1 - 3 8.1 8.8 10 6.4 0.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5466) DUF5427 PF10310.9 RJW64074.1 - 4.2 6.2 11.4 9.6 5.0 8.7 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5427) Presenilin PF01080.17 RJW64074.1 - 4.5 5.9 6.4 5.7 5.6 6.4 1.1 1 0 0 1 1 1 0 Presenilin Fibin PF15819.5 RJW64074.1 - 5.6 6.7 9.9 10 5.8 1.4 2.1 1 1 1 2 2 2 0 Fin bud initiation factor homologue Apt1 PF10351.9 RJW64074.1 - 9.2 5.0 12.4 10 4.8 12.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Innexin PF00876.18 RJW64077.1 - 1.8e-141 471.5 0.9 2e-108 362.8 0.6 3.1 3 0 0 3 3 3 3 Innexin Casc1 PF12366.8 RJW64077.1 - 0.015 14.8 0.0 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 Pro_CA PF00484.19 RJW64080.1 - 4.4e-20 72.6 0.0 5.3e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase CPW_WPC PF09717.10 RJW64082.1 - 0.092 13.7 0.1 0.24 12.4 0.1 1.6 1 0 0 1 1 1 0 Plasmodium falciparum domain of unknown function (CPW_WPC) ANAPC4_WD40 PF12894.7 RJW64083.1 - 1.6e-10 41.1 2.8 0.019 15.3 0.3 5.0 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 RJW64083.1 - 3e-06 27.2 2.4 7.8e-05 22.6 1.0 2.7 1 1 1 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.32 RJW64083.1 - 0.003 18.3 3.4 2.7 9.0 0.0 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat Synaptobrevin PF00957.21 RJW64083.1 - 0.054 13.3 0.3 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 Synaptobrevin Nbas_N PF15492.6 RJW64083.1 - 0.097 12.0 0.2 9.3 5.5 0.0 3.0 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PIG-P PF08510.12 RJW64084.1 - 3.3e-27 94.8 1.2 3.7e-27 94.7 1.2 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 RJW64084.1 - 0.013 15.8 11.1 0.029 14.6 10.2 2.0 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4764 PF15961.5 RJW64085.1 - 1.3e-10 40.7 4.2 1.5e-07 30.6 2.7 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4764) Ntox30 PF15532.6 RJW64085.1 - 0.0021 18.4 0.5 0.0064 16.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial toxin 30 zf-C2H2 PF00096.26 RJW64085.1 - 0.012 16.0 0.2 0.024 15.1 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW64085.1 - 0.13 13.2 0.2 0.27 12.2 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger P120R PF08062.11 RJW64085.1 - 5.9 7.4 5.5 4.3 7.8 2.8 2.2 2 0 0 2 2 2 0 P120R (NUC006) repeat DUF2076 PF09849.9 RJW64087.1 - 8.1e-06 26.1 0.2 9.2e-06 25.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 RJW64087.1 - 5.3e-05 23.2 1.2 8e-05 22.7 1.2 1.2 1 0 0 1 1 1 1 CHCH domain Linker_histone PF00538.19 RJW64089.1 - 4e-29 100.8 0.4 4e-29 100.8 0.4 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF908 PF06012.12 RJW64089.1 - 3.1 7.1 8.9 3.2 7.1 8.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ParcG PF10274.9 RJW64090.1 - 5.5e-22 78.8 0.0 7.1e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein RVT_1 PF00078.27 RJW64091.1 - 7.4e-24 84.5 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MLD PF11647.8 RJW64092.1 - 0.083 13.2 2.8 0.14 12.4 1.2 1.9 1 1 1 2 2 2 0 Membrane Localization Domain DND1_DSRM PF14709.7 RJW64092.1 - 0.26 11.6 1.8 0.4 11.0 0.1 1.9 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 SRCR PF00530.18 RJW64094.1 - 6.6e-25 87.5 6.3 8.9e-14 51.8 0.3 3.6 4 0 0 4 4 4 2 Scavenger receptor cysteine-rich domain Beta_helix PF13229.6 RJW64094.1 - 2.5e-11 43.7 55.9 0.00038 20.3 3.3 7.9 5 3 3 8 8 8 5 Right handed beta helix region SRCR_2 PF15494.6 RJW64094.1 - 1.4e-05 25.6 3.7 0.015 15.9 0.4 3.4 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain UL45 PF05473.12 RJW64094.1 - 0.002 17.8 0.3 0.0063 16.2 0.0 1.9 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Hepsin-SRCR PF09272.10 RJW64094.1 - 0.043 14.3 0.2 7.7 7.1 0.0 3.2 3 0 0 3 3 3 0 Hepsin, SRCR domain LRR_4 PF12799.7 RJW64095.1 - 1.3e-23 82.7 22.1 1.2e-05 25.5 1.9 6.3 3 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW64095.1 - 2.5e-17 62.9 4.8 4.4e-15 55.6 0.1 2.7 1 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 RJW64095.1 - 1.1e-14 53.9 17.8 2.5e-06 27.2 1.9 4.6 1 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 RJW64095.1 - 2.6e-05 23.9 11.2 0.7 10.1 0.1 6.6 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 RJW64095.1 - 0.0012 19.1 11.8 7.1 7.6 1.4 6.4 5 2 0 5 5 5 2 Leucine Rich Repeat DUF2849 PF11011.8 RJW64095.1 - 0.24 12.1 3.3 1.4 9.6 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) NPDC1 PF06809.11 RJW64096.1 - 0.0031 16.6 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) Claudin_2 PF13903.6 RJW64097.1 - 2.2e-14 53.7 6.4 3.5e-14 53.0 6.4 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RJW64097.1 - 6.1e-05 22.9 3.5 0.07 13.0 1.3 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 RJW64097.1 - 0.013 14.9 0.3 0.013 14.9 0.3 2.3 1 1 1 2 2 2 0 Clc-like L_HMGIC_fpl PF10242.9 RJW64097.1 - 0.027 14.7 10.0 0.051 13.8 7.8 2.2 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein GPHR_N PF12537.8 RJW64097.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal PGG PF13962.6 RJW64097.1 - 0.087 12.6 2.7 2.1 8.2 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function Claudin_3 PF06653.11 RJW64097.1 - 0.1 12.5 13.6 1 9.3 14.0 2.3 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Colicin_V PF02674.16 RJW64097.1 - 0.21 11.5 3.7 0.089 12.8 0.5 1.8 2 0 0 2 2 2 0 Colicin V production protein DUF5090 PF17009.5 RJW64097.1 - 0.43 10.5 2.2 0.36 10.8 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) DUF2448 PF10476.9 RJW64097.1 - 0.44 10.4 5.3 0.072 13.0 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Amastin PF07344.11 RJW64097.1 - 2 8.3 13.1 0.2 11.5 7.4 2.0 2 0 0 2 2 2 0 Amastin surface glycoprotein Peptidase_A17 PF05380.13 RJW64098.1 - 9.4e-46 155.8 0.0 1.8e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 RJW64098.1 - 7.9e-05 22.7 1.0 0.00016 21.7 1.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 RJW64100.1 - 7.7e-09 35.8 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RJW64100.1 - 5.5e-06 26.4 0.0 8.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RJW64100.1 - 6e-06 26.6 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RJW64100.1 - 0.00065 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Med22 PF06179.12 RJW64101.1 - 2.9e-21 75.7 0.6 4.2e-21 75.1 0.6 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Atg8 PF02991.16 RJW64103.1 - 1.4e-37 128.0 0.0 1.7e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RJW64103.1 - 4.5e-06 27.0 0.0 5.4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF4533 PF15047.6 RJW64105.1 - 0.0047 16.5 0.3 0.022 14.3 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4533) AATase PF07247.12 RJW64105.1 - 0.062 11.9 0.1 0.072 11.6 0.1 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase SUI1 PF01253.22 RJW64106.1 - 9e-26 90.2 1.4 1.2e-25 89.9 1.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 C2 PF00168.30 RJW64107.1 - 3.2e-34 117.3 0.2 7.1e-21 74.4 0.0 3.8 4 0 0 4 4 4 3 C2 domain Pex24p PF06398.11 RJW64107.1 - 0.066 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin CEP76-C2 PF15627.6 RJW64107.1 - 0.091 12.3 0.0 14 5.2 0.0 2.6 3 0 0 3 3 3 0 CEP76 C2 domain Rdx PF10262.9 RJW64108.1 - 9.2e-08 32.2 0.0 1.4e-07 31.6 0.0 1.3 1 1 0 1 1 1 1 Rdx family KH_1 PF00013.29 RJW64111.1 - 3.3e-12 46.0 0.5 3.2e-05 23.7 0.1 3.6 3 0 0 3 3 3 3 KH domain KH_9 PF17904.1 RJW64111.1 - 7.3e-10 39.1 0.0 2.4e-09 37.4 0.0 1.9 1 1 1 2 2 2 1 FMRP KH0 domain V_ATPase_I_N PF18670.1 RJW64111.1 - 0.034 14.5 0.5 0.1 13.0 0.2 2.0 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain RFX_DNA_binding PF02257.15 RJW64112.1 - 1.4e-31 108.9 0.0 2.6e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain PAP2 PF01569.21 RJW64112.1 - 0.16 11.7 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 PAP2 superfamily DUF825 PF05695.12 RJW64112.1 - 0.26 8.4 0.0 0.35 8.0 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) MAP70 PF07058.11 RJW64112.1 - 0.78 8.4 1.6 1.1 7.9 1.6 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 RVT_1 PF00078.27 RJW64116.1 - 3.7e-12 46.2 0.0 5.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chorein_N PF12624.7 RJW64116.1 - 0.045 13.9 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 PPV_E1_C PF00519.17 RJW64117.1 - 0.00024 20.1 0.0 0.00027 19.9 0.0 1.3 1 1 0 1 1 1 1 Papillomavirus helicase T2SSE PF00437.20 RJW64117.1 - 0.0032 16.6 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Parvo_NS1 PF01057.17 RJW64117.1 - 0.0069 15.5 0.0 0.0086 15.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 DUF2536 PF10750.9 RJW64117.1 - 0.015 15.2 0.1 7 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) TsaE PF02367.17 RJW64117.1 - 0.022 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 RJW64117.1 - 0.068 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SHR-BD PF06650.12 RJW64118.1 - 2.7e-33 115.5 0.0 3.4e-32 111.9 0.0 2.6 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 RJW64118.1 - 2.8e-24 85.8 6.3 3.7e-18 65.9 0.6 3.4 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 RJW64118.1 - 1.2e-11 44.6 0.0 4e-08 33.0 0.0 3.9 4 0 0 4 4 4 2 Repeating coiled region of VPS13 BTB PF00651.31 RJW64119.1 - 4.8e-16 59.0 0.0 2.9e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 RJW64119.1 - 3.8e-06 26.9 0.1 0.00015 21.8 0.2 2.9 3 0 0 3 3 3 1 BTB And C-terminal Kelch Neur_chan_memb PF02932.16 RJW64120.1 - 4.4e-32 112.1 0.0 7.5e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RJW64120.1 - 1.5e-26 93.2 0.4 6.9e-21 74.7 0.1 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain MFS_1 PF07690.16 RJW64121.1 - 2.7e-35 121.9 18.2 1e-21 77.3 0.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.21 RJW64122.1 - 4.3e-08 32.8 8.6 4.3e-08 32.8 8.6 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) HisKA_2 PF07568.12 RJW64122.1 - 0.083 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase Dynein_light PF01221.18 RJW64124.1 - 3.2e-29 101.1 0.5 3.6e-29 100.9 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Phage_cap_E PF03864.15 RJW64124.1 - 0.079 12.1 0.0 0.087 12.0 0.0 1.0 1 0 0 1 1 1 0 Phage major capsid protein E 7tm_1 PF00001.21 RJW64126.1 - 9.3e-08 31.7 2.1 9.3e-08 31.7 2.1 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) PI3_PI4_kinase PF00454.27 RJW64127.1 - 1.1e-37 130.3 0.0 2.2e-37 129.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 RJW64127.1 - 4.6e-19 68.3 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Serine/threonine-protein kinase smg-1 FATC PF02260.20 RJW64127.1 - 8.8e-13 47.8 0.4 2.7e-12 46.3 0.4 2.0 1 0 0 1 1 1 1 FATC domain Ank_2 PF12796.7 RJW64127.1 - 1.8e-10 41.3 0.0 8.7e-10 39.1 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW64127.1 - 2.5e-08 34.3 0.2 4.4e-07 30.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW64127.1 - 0.00015 21.9 0.2 10 7.1 0.0 4.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RJW64127.1 - 0.017 15.4 0.1 0.85 10.0 0.1 3.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 RJW64127.1 - 0.038 14.5 0.1 1.5 9.4 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat FRB_dom PF08771.11 RJW64127.1 - 0.05 14.0 0.7 10 6.6 0.2 3.3 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain Neur_chan_LBD PF02931.23 RJW64128.1 - 3.4e-51 173.8 2.8 5.3e-51 173.1 2.8 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW64128.1 - 4.1e-30 105.6 0.0 1.1e-29 104.3 0.0 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region AvrB_AvrC PF05394.11 RJW64128.1 - 0.093 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Avirulence protein RVT_1 PF00078.27 RJW64129.1 - 1.8e-28 99.6 0.0 3.8e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW64129.1 - 1.1e-06 28.4 0.0 3.9e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase ER_lumen_recept PF00810.18 RJW64130.1 - 4e-40 138.0 6.9 5.9e-40 137.5 6.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PrgI PF12666.7 RJW64130.1 - 0.31 11.8 2.8 0.64 10.8 2.7 1.8 1 1 0 1 1 1 0 PrgI family protein RhoGAP PF00620.27 RJW64133.1 - 2.1e-14 53.6 0.4 5.5e-14 52.3 0.4 1.7 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 RJW64133.1 - 2.3e-12 46.6 18.9 2.7e-08 33.6 1.4 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.24 RJW64133.1 - 7.7e-10 38.7 0.0 4.7e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 SH2 domain SAM_1 PF00536.30 RJW64133.1 - 0.0041 17.5 0.0 0.018 15.4 0.0 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SabA_adhesion PF18304.1 RJW64133.1 - 0.022 14.0 0.2 0.038 13.2 0.2 1.3 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain CagE_TrbE_VirB PF03135.14 RJW64133.1 - 0.34 11.0 1.6 1.4 9.0 0.8 2.2 2 0 0 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system PHD PF00628.29 RJW64133.1 - 2 8.4 19.9 1.8 8.5 2.5 2.7 2 0 0 2 2 2 0 PHD-finger ATG16 PF08614.11 RJW64133.1 - 3.2 7.9 14.6 9.7 6.4 14.6 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Vicilin_N PF04702.12 RJW64133.1 - 5.3 6.9 10.9 11 5.9 10.9 1.4 1 0 0 1 1 1 0 Vicilin N terminal region Neur_chan_memb PF02932.16 RJW64134.1 - 7.2e-29 101.5 0.0 1e-28 101.0 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RJW64134.1 - 5.1e-06 26.1 0.0 7.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF5090 PF17009.5 RJW64134.1 - 7.5 6.5 9.4 1.6 8.6 6.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) TRAP_alpha PF03896.16 RJW64135.1 - 2.8e-40 138.3 0.0 4.1e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Ras PF00071.22 RJW64137.1 - 3e-51 173.3 0.1 9.7e-51 171.6 0.1 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RJW64137.1 - 5.2e-26 91.2 0.0 1.5e-25 89.8 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW64137.1 - 4.8e-07 29.4 0.0 1.2e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW64137.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region HLH PF00010.26 RJW64138.1 - 2.4e-12 46.6 4.6 5e-12 45.6 4.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.32 RJW64139.1 - 3.8e-09 37.0 8.7 1.3e-06 29.0 0.1 6.0 6 1 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW64139.1 - 4.7e-05 23.6 0.0 7.9 6.8 0.0 3.8 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain TonB_N PF16031.5 RJW64139.1 - 2.1 8.8 8.8 4.6 7.8 8.8 1.5 1 0 0 1 1 1 0 TonB polyproline region DUF1067 PF06362.11 RJW64141.1 - 0.016 16.0 0.2 0.041 14.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1067) 7tm_1 PF00001.21 RJW64142.1 - 8.7e-20 71.1 1.5 1.5e-19 70.4 1.4 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW64142.1 - 2.4e-08 33.9 4.3 2.4e-08 33.9 4.3 2.1 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RJW64142.1 - 3.6e-08 33.1 13.7 6.3e-08 32.3 5.6 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 RJW64142.1 - 0.09 12.1 17.1 0.053 12.9 9.9 2.7 2 2 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 RJW64142.1 - 0.18 11.2 0.1 0.18 11.2 0.1 2.8 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM154 PF15102.6 RJW64142.1 - 0.39 10.6 3.8 0.26 11.2 0.7 2.1 2 0 0 2 2 2 0 TMEM154 protein family Nup188_C PF18378.1 RJW64143.1 - 0.065 12.1 0.1 0.081 11.7 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain DUF4821 PF16092.5 RJW64143.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Pkinase PF00069.25 RJW64145.1 - 3e-60 203.8 0.0 9.9e-60 202.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64145.1 - 1.6e-32 112.8 0.2 1.8e-22 79.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 RJW64145.1 - 1.4e-06 28.9 0.3 5.3e-06 27.0 0.2 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 RJW64145.1 - 0.00015 21.2 0.2 0.011 15.1 0.0 2.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RJW64145.1 - 0.00016 20.8 0.1 0.00025 20.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RJW64145.1 - 0.00037 19.9 0.0 0.00083 18.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW64145.1 - 0.0031 17.5 1.7 0.032 14.2 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RJW64145.1 - 0.029 13.2 0.0 0.06 12.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Zn_ribbon_SprT PF17283.2 RJW64146.1 - 0.1 12.5 0.4 0.1 12.5 0.4 2.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Rib_5-P_isom_A PF06026.14 RJW64147.1 - 9e-60 201.2 0.0 1.2e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 RJW64147.1 - 0.0013 18.7 0.4 0.1 12.5 0.1 2.1 1 1 1 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.13 RJW64147.1 - 0.0058 15.8 0.0 0.0084 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain Phosducin PF02114.16 RJW64149.1 - 5.4e-41 140.3 0.2 1e-39 136.1 0.2 2.2 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 RJW64149.1 - 9.8e-06 25.5 0.0 5.9e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin iPGM_N PF06415.13 RJW64149.1 - 0.085 12.3 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) RINGv PF12906.7 RJW64151.1 - 0.18 12.0 0.9 2 8.6 0.1 2.5 2 0 0 2 2 2 0 RING-variant domain Carb_anhydrase PF00194.21 RJW64153.1 - 6.1e-63 212.7 0.0 7.3e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Complex1_LYR_2 PF13233.6 RJW64154.1 - 1.8e-16 60.7 0.4 2.5e-16 60.2 0.4 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 RJW64154.1 - 1.5e-08 34.6 1.7 1.7e-08 34.3 0.3 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF3037 PF11236.8 RJW64154.1 - 0.099 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Galactosyl_T PF01762.21 RJW64156.1 - 0.091 12.6 0.1 0.87 9.4 0.0 2.4 2 1 1 3 3 3 0 Galactosyltransferase DEAD PF00270.29 RJW64158.1 - 1.7e-37 128.9 0.3 3.2e-37 128.0 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW64158.1 - 7.1e-30 103.6 0.1 2.5e-29 101.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW64158.1 - 4.4e-07 30.0 0.0 9.9e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RJW64158.1 - 1.5e-05 25.3 0.0 4.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 RJW64158.1 - 0.083 12.2 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit CHORD PF04968.12 RJW64159.1 - 0.065 14.0 0.1 0.065 14.0 0.1 2.7 3 0 0 3 3 3 0 CHORD Filamin PF00630.19 RJW64160.1 - 3.5e-235 763.4 17.8 5.6e-20 72.1 0.0 20.3 20 0 0 20 20 20 20 Filamin/ABP280 repeat Y_Y_Y PF07495.13 RJW64160.1 - 4.9e-14 52.0 5.8 0.45 10.5 0.0 10.0 11 0 0 11 11 11 4 Y_Y_Y domain Big_3_5 PF16640.5 RJW64160.1 - 1.7e-11 44.2 17.3 0.0052 16.9 0.2 11.0 12 0 0 12 12 12 2 Bacterial Ig-like domain (group 3) DUF5060 PF16586.5 RJW64160.1 - 0.00027 21.2 1.4 1.6e+02 2.8 0.0 8.6 10 0 0 10 10 10 0 Domain of unknown function (DUF5060) YtkA PF13115.6 RJW64160.1 - 0.012 16.2 1.3 1.4e+02 3.2 0.0 7.3 10 0 0 10 10 10 0 YtkA-like Big_1 PF02369.16 RJW64160.1 - 0.13 12.3 1.8 27 4.9 0.1 5.3 7 0 0 7 7 7 0 Bacterial Ig-like domain (group 1) Invasin_D3 PF09134.10 RJW64160.1 - 0.2 12.0 10.2 10 6.5 0.2 7.5 8 1 0 8 8 8 0 Invasin, domain 3 RA PF00788.23 RJW64162.1 - 7e-11 42.6 0.0 1.5e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 RJW64162.1 - 4.7e-09 36.0 2.7 1.1e-08 34.9 2.7 1.6 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain C1_1 PF00130.22 RJW64162.1 - 0.00027 20.7 14.5 0.00045 20.1 14.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ras_bdg_2 PF14847.6 RJW64162.1 - 0.028 14.7 0.5 0.064 13.6 0.0 1.9 2 0 0 2 2 2 0 Ras-binding domain of Byr2 Golgin_A5 PF09787.9 RJW64164.1 - 0.0028 17.2 3.0 0.0028 17.2 3.0 4.1 1 1 1 3 3 3 1 Golgin subfamily A member 5 ProSAAS PF07259.12 RJW64164.1 - 0.0097 15.9 1.5 0.0097 15.9 1.5 3.4 1 1 3 4 4 4 2 ProSAAS precursor Fez1 PF06818.15 RJW64164.1 - 1.5 9.3 61.7 0.24 11.8 24.1 3.2 1 1 2 3 3 3 0 Fez1 CRAL_TRIO PF00650.20 RJW64168.1 - 2.4e-16 59.9 0.1 3.1e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF739 PF05339.11 RJW64168.1 - 0.043 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF739) DUF3906 PF13046.6 RJW64168.1 - 0.12 12.4 0.0 7.5 6.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3906) EF1_GNE PF00736.19 RJW64169.1 - 2e-22 79.2 0.1 6.3e-22 77.6 0.0 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 RJW64169.1 - 6.5e-09 36.1 1.1 6.5e-09 36.1 1.1 2.7 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region BSP_II PF05432.11 RJW64169.1 - 0.014 15.1 2.2 0.018 14.7 2.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3619 PF12279.8 RJW64169.1 - 0.048 14.0 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) PAC1 PF16094.5 RJW64169.1 - 0.17 11.0 1.2 0.25 10.5 1.2 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Ank_2 PF12796.7 RJW64170.1 - 0.00022 21.8 0.0 0.0014 19.1 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW64170.1 - 0.089 13.4 0.0 0.36 11.5 0.0 1.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Nsp1_C PF05064.13 RJW64171.1 - 6.6e-31 106.5 6.0 1.4e-30 105.5 6.0 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region WD40 PF00400.32 RJW64171.1 - 8.8e-23 80.2 8.0 7.9e-05 23.4 0.1 7.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW64171.1 - 1.1e-06 28.8 0.0 0.011 16.0 0.0 3.7 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 RJW64171.1 - 0.00066 20.0 5.0 0.0015 18.8 5.0 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF16 PF01519.16 RJW64171.1 - 0.014 15.9 3.0 0.027 15.0 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 ALIX_LYPXL_bnd PF13949.6 RJW64171.1 - 0.041 13.2 3.6 0.064 12.5 3.6 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA_23 PF13476.6 RJW64171.1 - 0.066 13.7 0.0 0.099 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Prefoldin PF02996.17 RJW64171.1 - 0.084 12.8 0.4 0.17 11.8 0.4 1.5 1 0 0 1 1 1 0 Prefoldin subunit DUF4200 PF13863.6 RJW64171.1 - 0.12 12.8 4.0 0.21 12.0 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.15 RJW64171.1 - 0.25 10.9 3.7 0.4 10.2 3.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 RJW64171.1 - 0.34 10.2 3.1 0.72 9.1 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF148 PF02520.17 RJW64171.1 - 0.79 9.9 3.3 11 6.2 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 APG6_N PF17675.1 RJW64171.1 - 3.4 8.2 10.2 6 7.4 10.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 RJW64171.1 - 4.7 7.5 6.5 1.1 9.4 3.3 1.5 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding KH_1 PF00013.29 RJW64172.1 - 5.4e-11 42.2 0.0 1.3e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_9 PF17904.1 RJW64172.1 - 3.5e-08 33.7 0.1 0.00047 20.5 0.0 2.8 3 0 0 3 3 3 2 FMRP KH0 domain Agenet PF05641.12 RJW64172.1 - 0.0013 19.1 0.0 0.33 11.5 0.1 2.8 2 1 0 2 2 2 2 Agenet domain Vinculin PF01044.19 RJW64173.1 - 2.6e-97 327.2 24.5 1.9e-84 284.6 13.6 2.8 1 1 0 2 2 2 2 Vinculin family FUSC PF04632.12 RJW64173.1 - 0.0028 16.3 1.2 0.0028 16.3 1.2 2.4 2 1 1 3 3 3 1 Fusaric acid resistance protein family F_actin_bind PF08919.10 RJW64173.1 - 0.0054 16.8 9.0 0.42 10.7 0.0 4.4 4 0 0 4 4 4 2 F-actin binding I_LWEQ PF01608.17 RJW64173.1 - 0.23 11.7 0.0 0.23 11.7 0.0 4.2 5 0 0 5 5 5 0 I/LWEQ domain Xpo1 PF08389.12 RJW64173.1 - 0.25 11.4 1.6 1.2 9.2 0.1 2.5 2 0 0 2 2 2 0 Exportin 1-like protein DUF4709 PF15821.5 RJW64173.1 - 1.2 9.5 5.0 3.7 7.9 1.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) HECT PF00632.25 RJW64174.1 - 5.5e-42 144.3 0.0 8.7e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pro_isomerase PF00160.21 RJW64176.1 - 2.7e-16 60.2 0.0 3e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Dna2 PF08696.11 RJW64179.1 - 1.3e-35 123.0 0.0 3.7e-35 121.6 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 RJW64179.1 - 5.9e-16 59.0 0.0 5.9e-16 59.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RJW64179.1 - 4.2e-09 36.4 0.0 8.8e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 RJW64179.1 - 1.1e-07 32.0 0.0 2.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.6 RJW64179.1 - 4.1e-07 30.4 0.1 8.7e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 RJW64179.1 - 0.00091 19.3 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MobB PF03205.14 RJW64179.1 - 0.0069 16.3 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 RJW64179.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 RJW64179.1 - 0.023 14.2 0.1 0.023 14.2 0.1 1.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 RJW64179.1 - 0.037 13.9 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Helicase DUF853 PF05872.12 RJW64179.1 - 0.046 12.3 0.5 0.082 11.5 0.1 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_5 PF07728.14 RJW64179.1 - 0.051 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 RJW64179.1 - 0.056 13.2 0.0 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 RJW64179.1 - 0.099 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 RJW64179.1 - 0.099 13.0 0.7 0.22 11.9 0.1 1.9 2 0 0 2 2 1 0 AAA ATPase domain MeaB PF03308.16 RJW64179.1 - 0.11 11.5 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 RJW64179.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI INTS2 PF14750.6 RJW64180.1 - 1.7e-82 277.6 0.0 1.3e-80 271.3 0.0 2.0 1 1 0 1 1 1 1 Integrator complex subunit 2 Xlink PF00193.17 RJW64180.1 - 0.091 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Extracellular link domain SH3BP5 PF05276.14 RJW64182.1 - 7.8e-67 225.5 16.3 1.1e-66 224.9 16.3 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) FliJ PF02050.16 RJW64182.1 - 0.0054 16.9 7.3 0.0054 16.9 7.3 2.8 2 1 0 2 2 2 1 Flagellar FliJ protein UvsY PF11056.8 RJW64182.1 - 0.021 15.2 2.9 0.051 13.9 0.8 2.1 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY T3SSipB PF16535.5 RJW64182.1 - 7.7 7.0 8.6 9.9 6.6 0.3 2.8 1 1 1 2 2 2 0 Type III cell invasion protein SipB YlqD PF11068.8 RJW64182.1 - 9.9 6.5 11.8 2.3 8.6 1.7 2.6 1 1 2 3 3 3 0 YlqD protein PUF PF00806.19 RJW64184.1 - 1.3e-64 210.4 9.5 1.4e-09 37.1 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 RJW64184.1 - 0.017 15.4 0.8 4.4 7.6 0.1 4.1 3 1 1 4 4 4 0 CPL (NUC119) domain DUF4055 PF13264.6 RJW64184.1 - 0.17 12.1 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) TssR PF17643.1 RJW64186.1 - 0.074 11.0 0.0 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR Ecm29 PF13001.7 RJW64188.1 - 0.00028 19.7 0.2 0.084 11.5 0.1 2.3 2 0 0 2 2 2 2 Proteasome stabiliser CLASP_N PF12348.8 RJW64188.1 - 0.0046 16.5 1.0 0.56 9.7 0.1 3.0 2 1 1 3 3 3 1 CLASP N terminal HEAT PF02985.22 RJW64188.1 - 0.0096 16.1 3.0 0.12 12.7 0.1 4.2 6 0 0 6 6 6 1 HEAT repeat MMS19_C PF12460.8 RJW64188.1 - 0.018 14.2 0.1 0.081 12.0 0.0 2.1 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 RJW64188.1 - 0.063 13.5 0.3 11 6.2 0.0 3.6 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 RJW64188.1 - 0.17 12.5 0.0 1.2 9.7 0.0 2.5 1 0 0 1 1 1 0 HEAT-like repeat DHR-2 PF06920.13 RJW64189.1 - 1.1e-124 417.0 0.0 1.7e-124 416.4 0.0 1.2 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 RJW64189.1 - 7.7e-42 143.3 0.1 1.7e-41 142.2 0.1 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins RabGAP-TBC PF00566.18 RJW64190.1 - 2e-37 129.0 2.5 5.8e-26 91.5 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Ig_3 PF13927.6 RJW64190.1 - 7e-15 55.4 0.5 2.4e-09 37.6 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RJW64190.1 - 3e-11 43.3 0.1 2.9e-07 30.6 0.0 3.7 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RJW64190.1 - 8.4e-11 41.8 0.0 7.9e-08 32.3 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW64190.1 - 1e-05 25.8 0.3 0.0015 18.8 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 RJW64190.1 - 0.006 16.6 0.4 5 7.3 0.0 3.0 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain V-set PF07686.17 RJW64190.1 - 0.026 14.7 0.1 4.4 7.5 0.0 2.9 2 0 0 2 2 2 0 Immunoglobulin V-set domain Arg_repressor PF01316.21 RJW64191.1 - 0.0022 17.7 0.3 0.0067 16.2 0.3 1.8 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain Tmemb_cc2 PF10267.9 RJW64191.1 - 0.0075 15.5 1.8 0.0088 15.2 1.8 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein DUF4618 PF15397.6 RJW64191.1 - 0.05 13.0 4.3 0.11 12.0 3.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) SlyX PF04102.12 RJW64191.1 - 0.11 13.1 6.5 1.7 9.3 1.0 2.8 1 1 1 2 2 2 0 SlyX Med4 PF10018.9 RJW64191.1 - 0.13 11.9 3.9 0.073 12.7 1.6 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Pkinase PF00069.25 RJW64192.1 - 8.3e-22 77.8 0.0 1.3e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64192.1 - 1.5e-10 40.9 0.0 2.8e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 RJW64192.1 - 7.9e-05 22.2 3.8 0.00026 20.5 3.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) MIT PF04212.18 RJW64192.1 - 0.11 12.5 3.9 0.051 13.7 1.3 1.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF5405 PF17399.2 RJW64192.1 - 0.17 12.2 0.4 22 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5405) ArnB_C PF18677.1 RJW64192.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Hexokinase_2 PF03727.16 RJW64193.1 - 6.3e-79 264.8 0.0 9e-79 264.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 RJW64193.1 - 5.8e-63 212.4 0.0 8.2e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Fe_dep_repr_C PF02742.15 RJW64196.1 - 0.012 15.6 0.1 3.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain 7tm_1 PF00001.21 RJW64197.1 - 1.9e-49 168.4 15.1 4.4e-49 167.2 15.1 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW64197.1 - 1.3e-15 57.5 5.5 8.6e-15 54.8 3.1 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RJW64197.1 - 2.2e-09 37.3 9.4 3.9e-09 36.5 9.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 RJW64197.1 - 0.0041 16.7 10.4 0.0083 15.7 10.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_4 PF13853.6 RJW64197.1 - 0.008 15.9 1.3 0.014 15.1 1.3 1.3 1 0 0 1 1 1 1 Olfactory receptor INTS2 PF14750.6 RJW64198.1 - 3.6e-55 187.1 6.3 4.2e-54 183.6 6.3 1.9 1 1 0 1 1 1 1 Integrator complex subunit 2 Antistasin PF02822.14 RJW64199.1 - 1.7e-05 25.3 25.5 5.2e-05 23.8 9.4 2.7 2 1 0 2 2 2 2 Antistasin family MFS_1 PF07690.16 RJW64200.1 - 7.9e-21 74.4 31.7 3e-20 72.5 11.6 2.1 2 1 1 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.16 RJW64200.1 - 0.0014 18.3 17.3 0.098 12.4 5.8 3.6 3 1 0 3 3 3 2 Ion channel regulatory protein UNC-93 SP24 PF16504.5 RJW64200.1 - 0.024 14.7 0.4 9.2 6.3 0.0 3.4 3 0 0 3 3 3 0 Putative virion membrane protein of plant and insect virus P2X_receptor PF00864.19 RJW64201.1 - 2.3e-146 487.6 0.6 3.1e-146 487.2 0.6 1.1 1 0 0 1 1 1 1 ATP P2X receptor G0-G1_switch_2 PF15103.6 RJW64201.1 - 0.0068 16.8 0.2 0.014 15.8 0.2 1.5 1 0 0 1 1 1 1 G0/G1 switch protein 2 MAT1 PF06391.13 RJW64201.1 - 0.022 14.6 4.6 0.035 13.9 4.6 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 WAP PF00095.21 RJW64201.1 - 1.2 9.6 4.5 9.3 6.7 0.6 3.0 3 0 0 3 3 3 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Cytadhesin_P30 PF07271.11 RJW64201.1 - 1.6 8.2 4.7 0.56 9.7 0.5 2.0 2 0 0 2 2 2 0 Cytadhesin P30/P32 SRP19 PF01922.17 RJW64204.1 - 1.9e-23 83.2 0.0 3.6e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein DUF5571 PF17732.1 RJW64204.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5571) RT_RNaseH_2 PF17919.1 RJW64205.1 - 1e-16 60.8 0.0 1.9e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW64205.1 - 7.8e-13 48.4 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 RJW64205.1 - 0.00011 22.4 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chorein_N PF12624.7 RJW64206.1 - 2.9e-13 49.9 0.3 7.2e-13 48.7 0.3 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 TPR_12 PF13424.6 RJW64208.1 - 1.1e-10 41.6 9.1 8.7e-06 25.9 0.1 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW64208.1 - 4.6e-08 32.7 1.9 0.024 14.8 0.0 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW64208.1 - 5.6e-07 29.2 1.0 1.9 8.8 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW64208.1 - 0.00025 20.9 0.6 0.52 10.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 RJW64208.1 - 0.0011 18.8 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_MalT PF17874.1 RJW64208.1 - 0.0034 16.8 2.5 0.32 10.3 0.1 2.9 2 1 0 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 RJW64208.1 - 0.0087 15.8 0.2 21 5.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RJW64208.1 - 0.013 15.4 2.5 1.2 9.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat COX5A PF02284.16 RJW64208.1 - 0.075 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Sel1 PF08238.12 RJW64208.1 - 0.09 13.5 0.2 3.4 8.5 0.1 3.0 2 1 1 3 3 3 0 Sel1 repeat TPR_4 PF07721.14 RJW64208.1 - 1.3 9.9 10.7 19 6.3 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 RJW64209.1 - 4.8e-51 170.5 0.1 7.1e-16 57.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW64209.1 - 4.4e-06 26.3 0.0 0.18 11.4 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 RJW64209.1 - 0.00041 20.5 0.0 0.34 11.2 0.0 3.2 3 0 0 3 3 3 1 BRCA1-associated protein 2 RRM_7 PF16367.5 RJW64209.1 - 0.0033 17.5 0.0 0.56 10.4 0.0 3.1 3 1 0 3 3 3 1 RNA recognition motif Arm PF00514.23 RJW64213.1 - 1.8e-52 173.8 18.7 1e-06 28.6 0.0 12.7 13 0 0 13 13 13 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RJW64213.1 - 5.9e-15 55.4 6.3 0.004 17.5 0.1 7.7 4 4 6 10 10 10 4 HEAT repeats Adaptin_N PF01602.20 RJW64213.1 - 7e-10 38.1 0.4 0.00084 18.0 0.0 3.4 2 1 1 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 RJW64213.1 - 3.8e-07 30.5 8.7 0.045 14.3 0.2 7.4 7 2 2 9 9 9 3 HEAT-like repeat HEAT PF02985.22 RJW64213.1 - 7.9e-07 28.8 11.8 1.8 9.1 0.1 7.0 8 0 0 8 8 7 4 HEAT repeat KAP PF05804.12 RJW64213.1 - 1.8e-05 23.1 0.8 0.18 9.9 0.0 4.2 2 1 1 4 4 4 2 Kinesin-associated protein (KAP) Cnd1 PF12717.7 RJW64213.1 - 0.00017 21.6 0.6 6.8 6.7 0.0 4.0 1 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 RJW64213.1 - 0.00032 20.8 0.0 8.7 6.5 0.0 5.5 3 1 3 7 7 7 1 V-ATPase subunit H RICTOR_N PF14664.6 RJW64213.1 - 0.011 14.8 0.7 0.79 8.7 0.0 3.7 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term CTNNBL PF08216.11 RJW64213.1 - 0.019 15.2 0.1 49 4.2 0.0 5.0 5 1 1 6 6 6 0 Catenin-beta-like, Arm-motif containing nuclear Drf_GBD PF06371.13 RJW64213.1 - 2.6 7.6 5.6 0.94 9.0 0.1 2.8 2 1 0 2 2 2 0 Diaphanous GTPase-binding Domain APG6_N PF17675.1 RJW64214.1 - 9.4e-05 22.9 32.0 0.00014 22.4 8.1 9.6 3 2 7 10 10 10 5 Apg6 coiled-coil region HMMR_N PF15905.5 RJW64214.1 - 0.00053 19.6 17.2 0.00053 19.6 17.2 6.4 3 2 3 6 6 6 3 Hyaluronan mediated motility receptor N-terminal Takusan PF04822.13 RJW64214.1 - 0.003 17.4 4.6 0.003 17.4 4.6 9.2 7 3 4 11 11 11 2 Takusan Bap31_Bap29_C PF18035.1 RJW64214.1 - 0.058 13.4 0.1 0.058 13.4 0.1 6.3 7 0 0 7 7 7 0 Bap31/Bap29 cytoplasmic coiled-coil domain Fez1 PF06818.15 RJW64214.1 - 0.3 11.5 101.7 0.025 15.0 19.2 7.3 3 2 5 8 8 8 0 Fez1 WD40 PF00400.32 RJW64215.1 - 0.0058 17.4 8.1 28 5.8 0.0 6.3 7 1 0 7 7 7 2 WD domain, G-beta repeat WD40 PF00400.32 RJW64216.1 - 2.1e-09 37.8 8.9 0.001 19.8 1.1 6.4 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW64216.1 - 3e-07 30.7 0.1 0.23 11.8 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW64216.1 - 0.013 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein COesterase PF00135.28 RJW64216.1 - 0.083 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family NTP_transf_2 PF01909.23 RJW64217.1 - 0.00021 21.5 0.1 0.00039 20.7 0.1 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1461 PF07314.11 RJW64217.1 - 0.092 12.6 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Polbeta PF18765.1 RJW64217.1 - 0.16 12.0 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase FF PF01846.19 RJW64218.1 - 1.2e-44 150.3 30.2 1.3e-13 50.9 1.5 4.7 4 0 0 4 4 4 4 FF domain WW PF00397.26 RJW64218.1 - 1.9e-20 72.6 16.5 3.2e-08 33.5 3.9 3.8 3 0 0 3 3 3 3 WW domain RhoGAP-FF1 PF16512.5 RJW64218.1 - 0.00028 21.5 1.8 0.00028 21.5 1.8 3.5 2 1 1 3 3 3 1 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 RJW64218.1 - 0.56 10.5 3.0 19 5.6 0.2 3.3 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain RVT_1 PF00078.27 RJW64219.1 - 6.1e-45 153.4 0.0 1.3e-44 152.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rtt106 PF08512.12 RJW64219.1 - 1.1e-22 80.3 0.1 3.4e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HMG_box PF00505.19 RJW64219.1 - 5.9e-15 55.4 1.2 1.6e-14 54.1 1.2 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box SSrecog PF03531.14 RJW64219.1 - 5.1e-13 48.7 0.0 5.1e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) HMG_box_2 PF09011.10 RJW64219.1 - 9.6e-12 45.3 1.0 9.6e-12 45.3 1.0 1.9 2 0 0 2 2 2 1 HMG-box domain CDC45 PF02724.14 RJW64219.1 - 0.96 7.7 12.8 1.4 7.1 12.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4783 PF16022.5 RJW64221.1 - 0.013 15.6 0.3 0.019 15.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) Laminin_EGF PF00053.24 RJW64222.1 - 6.2e-84 276.0 173.6 3.4e-11 43.1 12.2 10.3 9 1 1 10 10 10 10 Laminin EGF domain Laminin_N PF00055.17 RJW64222.1 - 3e-42 144.8 0.9 3e-42 144.8 0.9 3.3 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Ion_trans PF00520.31 RJW64223.1 - 1.4e-11 44.2 17.5 8.2e-08 31.8 9.1 2.2 2 0 0 2 2 2 2 Ion transport protein DivIVA PF05103.13 RJW64223.1 - 0.00013 22.0 0.3 0.41 10.7 0.0 2.8 2 0 0 2 2 2 2 DivIVA protein CK2S PF15011.6 RJW64223.1 - 0.0089 15.9 2.6 1.8 8.4 0.2 2.5 2 0 0 2 2 2 2 Casein Kinase 2 substrate Fib_alpha PF08702.10 RJW64223.1 - 0.14 12.3 1.1 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 RJW64223.1 - 0.37 11.5 2.4 36 5.2 0.1 3.2 2 0 0 2 2 2 0 Occludin homology domain RVT_1 PF00078.27 RJW64224.1 - 9.9e-46 156.0 0.0 1.8e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ICMT PF04140.14 RJW64225.1 - 1.1e-25 89.8 1.0 2e-25 89.0 1.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 RJW64225.1 - 4.3e-11 43.2 0.5 7.5e-11 42.4 0.5 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 RJW64225.1 - 0.027 14.0 0.6 0.03 13.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Polysacc_synt_3 PF13440.6 RJW64225.1 - 0.096 11.9 0.5 0.12 11.6 0.5 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UQ_con PF00179.26 RJW64226.1 - 4.4e-33 113.9 0.0 3.8e-32 110.8 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme F-box PF00646.33 RJW64226.1 - 6.8e-10 38.6 0.7 2.2e-09 37.0 0.7 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 RJW64226.1 - 8.4e-08 32.1 0.2 1.8e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 RJW64226.1 - 1.1e-07 31.6 0.1 3.4e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 RJW64226.1 - 0.0013 18.6 0.6 0.0061 16.5 0.6 2.0 2 0 0 2 2 2 1 F-box-like domain RWD PF05773.22 RJW64226.1 - 0.017 15.4 0.2 0.42 10.9 0.0 2.4 2 0 0 2 2 2 0 RWD domain ATP_bind_1 PF03029.17 RJW64227.1 - 6.5e-72 242.2 0.2 7.2e-46 156.9 0.0 2.0 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 RJW64227.1 - 5.6e-05 23.1 0.0 0.00072 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RJW64227.1 - 0.00091 19.5 0.0 0.0045 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 RJW64227.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 RJW64227.1 - 0.0023 17.7 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 RJW64227.1 - 0.0027 17.8 0.0 0.0037 17.3 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 RJW64227.1 - 0.0032 17.9 0.0 0.025 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ArsA_ATPase PF02374.15 RJW64227.1 - 0.0033 16.6 0.0 0.0072 15.5 0.0 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase AAA PF00004.29 RJW64227.1 - 0.0044 17.4 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 RJW64227.1 - 0.0058 15.6 0.0 0.0093 15.0 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 RJW64227.1 - 0.016 15.7 0.0 0.051 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RJW64227.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 RJW64227.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 RJW64227.1 - 0.019 15.5 0.1 0.057 14.0 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.14 RJW64227.1 - 0.038 14.0 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RJW64227.1 - 0.04 14.1 0.0 0.09 12.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 RJW64227.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 RJW64227.1 - 0.1 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 RJW64227.1 - 0.11 13.0 0.0 0.44 11.1 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 RJW64227.1 - 0.11 12.5 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RJW64227.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RJW64227.1 - 0.16 11.8 0.1 0.85 9.5 0.0 1.9 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 RJW64227.1 - 0.17 12.3 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RA PF00788.23 RJW64228.1 - 4.1e-07 30.5 0.0 8.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Peptidase_M29 PF02073.15 RJW64228.1 - 0.15 10.9 3.8 0.071 11.9 1.0 1.6 1 1 1 2 2 2 0 Thermophilic metalloprotease (M29) FAM76 PF16046.5 RJW64228.1 - 0.75 9.1 2.9 0.53 9.6 0.1 1.8 2 0 0 2 2 2 0 FAM76 protein ADIP PF11559.8 RJW64228.1 - 6 6.9 17.7 0.52 10.4 3.7 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PXA PF02194.15 RJW64230.1 - 1.3e-45 155.6 3.0 3.6e-45 154.2 2.7 2.0 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 RJW64230.1 - 2.9e-20 72.9 0.0 1.8e-19 70.3 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 RJW64230.1 - 1.9e-16 60.1 0.0 4.7e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.19 RJW64230.1 - 0.0084 16.4 0.3 0.71 10.2 0.0 3.6 4 0 0 4 4 4 1 Regulator of G protein signaling domain Med20 PF08612.11 RJW64232.1 - 2.1e-27 95.9 0.0 2.9e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex zf-C2H2 PF00096.26 RJW64235.1 - 2.7e-12 46.4 28.8 4.6e-05 23.6 3.0 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW64235.1 - 5.3e-07 29.8 27.0 5.3e-06 26.6 1.9 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW64235.1 - 1.8e-06 28.3 24.9 0.014 16.2 3.0 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RJW64235.1 - 0.0004 20.1 6.6 0.0004 20.1 6.6 3.2 3 0 0 3 3 3 1 C2H2-type zinc-finger domain RPAP2_Rtr1 PF04181.13 RJW64235.1 - 0.47 10.8 0.1 0.47 10.8 0.1 3.1 3 0 0 3 3 3 0 Rtr1/RPAP2 family SOCS_box PF07525.16 RJW64236.1 - 0.0048 17.2 0.7 0.012 15.9 0.7 1.7 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 RJW64236.1 - 0.035 14.7 0.1 0.079 13.6 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Cyclin_N PF00134.23 RJW64237.1 - 2.4e-20 72.6 0.2 4.6e-20 71.7 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RJW64237.1 - 1.8e-09 37.7 1.0 5.9e-09 36.0 0.3 2.1 2 1 0 2 2 2 1 Cyclin, C-terminal domain HTH_17 PF12728.7 RJW64238.1 - 0.052 13.7 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain LRR_6 PF13516.6 RJW64241.1 - 1.9e-19 68.0 10.6 0.0015 18.4 0.0 6.7 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.33 RJW64241.1 - 4.4e-05 23.4 5.6 3.4 8.6 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 RJW64241.1 - 0.00027 21.3 15.3 0.17 12.4 1.1 4.9 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW64241.1 - 0.0062 16.3 11.7 0.15 11.9 0.6 4.4 1 1 4 5 5 5 4 Leucine rich repeat GST_C_3 PF14497.6 RJW64242.1 - 4.2e-16 58.9 0.0 5.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RJW64242.1 - 1.8e-11 44.2 0.0 4.3e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RJW64242.1 - 8.1e-07 29.2 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RJW64242.1 - 1.8e-06 27.6 0.1 4.8e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RJW64242.1 - 2.3e-05 24.3 0.0 7.2e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RJW64242.1 - 0.00043 20.7 0.1 0.022 15.2 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Telomere_Sde2_2 PF13297.6 RJW64243.1 - 3.2e-25 87.5 0.0 7.9e-25 86.3 0.0 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 RJW64243.1 - 9.5e-10 38.5 6.0 1.9e-09 37.5 6.0 1.5 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain DUF3435 PF11917.8 RJW64243.1 - 0.25 10.2 3.5 0.25 10.2 3.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3435) Glyco_transf_7N PF13733.6 RJW64244.1 - 5.3e-40 136.2 0.0 8.9e-40 135.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RJW64244.1 - 2.5e-24 84.7 0.0 3.9e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DRY_EERY PF09750.9 RJW64245.1 - 5.4e-23 81.8 0.2 5.4e-23 81.8 0.2 2.6 2 0 0 2 2 2 1 Alternative splicing regulator Ldh_1_N PF00056.23 RJW64246.1 - 7.5e-37 126.6 0.1 1.5e-36 125.5 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 RJW64246.1 - 4.9e-35 120.9 0.0 1e-34 119.8 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_3_C PF01915.22 RJW64246.1 - 0.042 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF3585 PF12130.8 RJW64249.1 - 1.1e-28 100.1 25.1 1.1e-28 100.1 25.1 2.1 3 0 0 3 3 3 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 RJW64249.1 - 3.5e-18 65.8 0.0 8.1e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain NT-C2 PF10358.9 RJW64249.1 - 1.1e-13 51.2 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins CAMSAP_CH PF11971.8 RJW64249.1 - 2.3e-06 27.4 0.0 6.3e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 RJW64249.1 - 0.074 13.2 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 CH-like domain in sperm protein FlaC_arch PF05377.11 RJW64249.1 - 0.89 10.0 3.9 0.73 10.3 1.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cas_St_Csn2 PF16813.5 RJW64252.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St Prefoldin PF02996.17 RJW64253.1 - 1.4e-25 89.5 3.3 1.9e-25 89.1 3.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Nucleoporin_C PF03177.14 RJW64253.1 - 0.017 13.9 0.6 0.023 13.5 0.6 1.2 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal Osmo_CC PF08946.10 RJW64253.1 - 2.2 8.6 7.1 0.29 11.4 0.5 2.7 2 1 0 2 2 2 0 Osmosensory transporter coiled coil DUF1007 PF06226.13 RJW64254.1 - 0.013 15.4 0.2 0.027 14.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) Prismane PF03063.20 RJW64255.1 - 0.0028 16.4 2.5 0.004 15.9 2.5 1.2 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family IQ PF00612.27 RJW64255.1 - 0.044 13.6 1.5 0.13 12.1 1.5 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fib_alpha PF08702.10 RJW64255.1 - 0.19 11.9 12.2 2 8.6 0.3 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 RJW64255.1 - 0.56 10.3 24.3 1 9.4 2.9 2.6 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ubiquitin PF00240.23 RJW64255.1 - 1.8 8.4 6.4 2.4 8.0 0.0 3.5 4 1 0 4 4 4 0 Ubiquitin family Pyr_redox PF00070.27 RJW64255.1 - 3.1 8.4 5.3 2.2 8.9 0.4 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FUSC PF04632.12 RJW64255.1 - 3.3 6.1 3.9 1.3 7.5 0.8 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family Spectrin PF00435.21 RJW64255.1 - 4.7 7.8 13.9 7.2 7.2 3.2 3.0 2 1 1 3 3 3 0 Spectrin repeat Pan3_PK PF18101.1 RJW64256.1 - 2.4e-48 163.6 0.2 6.9e-48 162.1 0.2 1.8 2 0 0 2 2 2 1 Pan3 Pseudokinase domain Pkinase_Tyr PF07714.17 RJW64256.1 - 0.0057 16.0 0.0 0.02 14.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RJW64256.1 - 0.068 12.5 0.0 0.66 9.3 0.0 2.2 1 1 0 1 1 1 0 Protein kinase domain EMP24_GP25L PF01105.24 RJW64257.1 - 5e-16 59.2 0.0 1.1e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Tmemb_cc2 PF10267.9 RJW64257.1 - 0.076 12.1 0.0 0.076 12.1 0.0 1.8 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein PWWP PF00855.17 RJW64258.1 - 5e-28 97.4 4.1 4.1e-15 55.9 0.1 3.6 3 0 0 3 3 3 2 PWWP domain SET PF00856.28 RJW64258.1 - 1.6e-18 67.6 0.0 2.8e-17 63.6 0.0 2.9 3 0 0 3 3 3 1 SET domain PHD PF00628.29 RJW64258.1 - 2.8e-09 36.7 61.7 1.7e-05 24.6 2.5 6.6 5 1 1 6 6 6 4 PHD-finger C5HCH PF17982.1 RJW64258.1 - 3e-06 27.3 5.7 3e-06 27.3 5.7 4.9 5 1 0 5 5 5 1 NSD Cys-His rich domain FYVE_2 PF02318.16 RJW64258.1 - 0.0018 18.5 2.2 0.0018 18.5 2.2 5.2 4 2 1 5 5 5 1 FYVE-type zinc finger C1_1 PF00130.22 RJW64258.1 - 0.0028 17.5 7.3 0.0028 17.5 7.3 6.9 5 1 1 6 6 6 1 Phorbol esters/diacylglycerol binding domain (C1 domain) UQ_con PF00179.26 RJW64259.1 - 1e-27 96.5 0.0 1.3e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RING_2 PF13639.6 RJW64261.1 - 5.2e-12 45.9 7.1 5.2e-12 45.9 7.1 4.9 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 RJW64261.1 - 1e-09 38.1 6.8 1e-09 38.1 6.8 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RJW64261.1 - 2e-09 37.0 8.8 9.7e-09 34.8 2.9 3.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 RJW64261.1 - 8.5e-07 28.7 5.0 8.5e-07 28.7 5.0 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW64261.1 - 1.4e-06 28.5 5.6 1.4e-06 28.5 5.6 4.1 4 1 1 5 5 5 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RJW64261.1 - 3e-06 27.1 3.8 3e-06 27.1 3.8 3.4 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RJW64261.1 - 2.3e-05 24.3 4.2 2.3e-05 24.3 4.2 2.8 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RJW64261.1 - 0.00027 20.7 8.0 0.00027 20.7 8.0 3.8 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 HTH_psq PF05225.16 RJW64262.1 - 3.6e-10 39.4 0.0 1.2e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Mitofilin PF09731.9 RJW64264.1 - 5.7e-78 263.3 8.3 6.6e-77 259.8 8.3 2.0 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Ribonuc_2-5A PF06479.12 RJW64264.1 - 0.092 12.9 1.9 0.35 11.0 1.9 2.0 1 0 0 1 1 1 0 Ribonuclease 2-5A TRAM_LAG1_CLN8 PF03798.16 RJW64265.1 - 2.3e-25 89.5 10.3 2.3e-25 89.5 10.3 1.9 2 0 0 2 2 2 1 TLC domain DUF3307 PF11750.8 RJW64265.1 - 0.0008 19.5 0.4 0.0013 18.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3307) INSIG PF07281.12 RJW64266.1 - 3.5e-24 85.7 4.0 6.6e-24 84.7 3.9 1.5 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) NTF2 PF02136.20 RJW64270.1 - 8.5e-16 58.6 0.1 1e-15 58.4 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 RJW64270.1 - 0.077 13.4 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) rve PF00665.26 RJW64273.1 - 9.4e-13 48.4 0.0 2.9e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW64273.1 - 6.1e-11 42.3 3.3 6.9e-11 42.1 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 RJW64273.1 - 0.034 13.9 0.1 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain Barwin PF00967.17 RJW64274.1 - 0.073 12.9 0.2 0.076 12.9 0.2 1.1 1 0 0 1 1 1 0 Barwin family MH1 PF03165.16 RJW64277.1 - 5.6e-11 42.6 0.4 2.2e-10 40.6 0.1 2.1 2 0 0 2 2 2 1 MH1 domain zf-NOSIP PF15906.5 RJW64277.1 - 0.096 12.8 2.5 16 5.7 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger of nitric oxide synthase-interacting protein Nramp PF01566.18 RJW64278.1 - 6.9e-103 344.4 10.7 7.9e-103 344.2 10.7 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein KH_1 PF00013.29 RJW64279.1 - 2.2e-40 136.3 7.5 7.7e-16 57.7 2.1 3.5 3 0 0 3 3 3 3 KH domain RRM_1 PF00076.22 RJW64279.1 - 8.5e-13 47.9 0.2 1.7e-12 47.0 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.17 RJW64279.1 - 4.5e-12 45.6 9.0 0.00027 20.7 0.1 3.5 2 1 1 3 3 3 3 KH domain KH_4 PF13083.6 RJW64279.1 - 6.8e-05 22.7 4.0 0.5 10.3 0.4 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 RJW64279.1 - 8.1e-05 22.6 4.2 0.52 10.4 0.3 3.5 3 0 0 3 3 3 2 NusA-like KH domain Nup35_RRM_2 PF14605.6 RJW64279.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif COMPASS-Shg1 PF05205.12 RJW64280.1 - 3.2e-17 63.1 0.7 3.2e-17 63.1 0.7 2.2 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 Ank_4 PF13637.6 RJW64284.1 - 8.9e-17 61.2 0.1 4.6e-13 49.4 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW64284.1 - 5.7e-14 52.0 0.1 5.1e-06 26.7 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW64284.1 - 6.8e-14 52.2 0.0 1.9e-12 47.6 0.0 3.1 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 RJW64284.1 - 4e-13 49.2 0.0 2.4e-06 27.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 RJW64284.1 - 1e-12 47.0 0.5 2.6e-06 27.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat zf-MYND PF01753.18 RJW64284.1 - 6.8e-09 35.7 10.3 1.4e-08 34.7 10.3 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 RJW64284.1 - 9.7 6.2 9.7 17 5.4 6.1 2.8 2 1 0 2 2 2 0 HIT zinc finger Kelch_1 PF01344.25 RJW64285.1 - 9.7e-65 214.0 14.4 4.2e-15 55.0 0.0 7.1 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 RJW64285.1 - 2.3e-36 122.9 7.9 7.3e-09 35.6 0.0 6.4 2 1 4 6 6 6 6 Kelch motif Kelch_2 PF07646.15 RJW64285.1 - 3e-28 96.7 3.8 9.2e-07 28.6 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RJW64285.1 - 1.2e-21 76.4 5.4 0.00018 21.4 0.0 5.6 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 RJW64285.1 - 3.7e-20 71.7 4.9 0.0004 20.6 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain BACK PF07707.15 RJW64285.1 - 2e-19 69.6 1.8 4.1e-19 68.6 1.8 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 RJW64285.1 - 1.3e-16 60.1 4.5 0.0018 18.2 0.0 6.4 6 0 0 6 6 6 3 Kelch motif LRR_6 PF13516.6 RJW64286.1 - 3.2e-19 67.3 11.8 0.011 15.7 0.0 8.7 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 RJW64286.1 - 3.3e-07 30.5 12.3 0.019 15.4 0.0 5.6 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW64286.1 - 0.00014 21.6 10.2 0.75 9.6 0.6 5.5 5 2 1 6 6 6 3 Leucine rich repeat Pentapeptide_4 PF13599.6 RJW64286.1 - 0.04 14.1 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) LRR_1 PF00560.33 RJW64286.1 - 0.059 13.9 10.8 5.4 8.0 0.0 6.6 7 1 0 7 7 7 0 Leucine Rich Repeat DUF1759 PF03564.15 RJW64287.1 - 0.0065 16.4 0.1 0.0097 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) zf-C2H2_9 PF16293.5 RJW64287.1 - 0.016 15.1 0.6 0.24 11.3 0.0 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Sulfotransfer_4 PF17784.1 RJW64287.1 - 0.098 12.5 0.3 0.13 12.1 0.3 1.2 1 1 0 1 1 1 0 Sulfotransferase domain PAN_1 PF00024.26 RJW64288.1 - 1.3e-05 25.1 1.9 2.5e-05 24.2 1.9 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 RJW64288.1 - 0.1 12.8 2.8 0.21 11.7 2.8 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.6 RJW64288.1 - 0.22 11.5 2.2 0.52 10.3 2.2 1.6 1 0 0 1 1 1 0 PAN domain DUF1759 PF03564.15 RJW64289.1 - 1.2e-06 28.5 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) AATF-Che1 PF13339.6 RJW64289.1 - 0.16 12.7 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Ncstrn_small PF18266.1 RJW64290.1 - 2.2e-39 135.2 0.8 5.4e-39 133.9 0.2 1.9 2 0 0 2 2 2 1 Nicastrin small lobe Nicastrin PF05450.15 RJW64290.1 - 7.2e-23 81.3 0.0 1.1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Nicastrin AA_permease_2 PF13520.6 RJW64294.1 - 4.2e-43 147.8 23.5 4.6e-43 147.6 23.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RJW64294.1 - 1e-21 77.1 19.8 1.2e-21 76.9 19.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF21 PF01595.20 RJW64296.1 - 4.3e-35 121.0 1.4 8.5e-35 120.0 1.4 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 RJW64296.1 - 2.1e-05 24.8 0.3 0.0054 17.1 0.1 2.6 2 0 0 2 2 2 2 CBS domain TGF_beta PF00019.20 RJW64297.1 - 1.2e-31 109.8 0.6 2.9e-31 108.5 0.6 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 RJW64297.1 - 0.015 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 TGF-beta propeptide Stb3 PF10330.9 RJW64297.1 - 0.095 12.7 0.2 0.27 11.3 0.2 1.9 1 1 0 1 1 1 0 Putative Sin3 binding protein PLDc_3 PF13918.6 RJW64298.1 - 6.3e-38 130.2 0.0 1.4e-37 129.1 0.0 1.5 2 0 0 2 2 2 1 PLD-like domain PLDc_2 PF13091.6 RJW64298.1 - 2.8e-21 75.8 0.0 2e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RJW64298.1 - 1.2e-10 41.1 1.6 3.6e-06 26.9 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif FHA PF00498.26 RJW64301.1 - 1.3e-16 60.7 0.0 2.6e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RJW64301.1 - 0.013 15.8 0.0 0.11 12.8 0.0 2.3 1 1 1 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain DUF2785 PF10978.8 RJW64301.1 - 0.079 12.7 0.1 0.079 12.7 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2785) ADIP PF11559.8 RJW64301.1 - 1.6 8.8 21.4 0.48 10.5 15.7 2.3 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 RJW64301.1 - 5.4 7.0 29.4 0.23 11.5 14.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4349 PF14257.6 RJW64301.1 - 8.7 5.7 10.6 2.8 7.3 7.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Dopey_N PF04118.14 RJW64302.1 - 1.9e-90 303.1 0.0 2.2e-89 299.6 0.0 2.3 2 0 0 2 2 2 1 Dopey, N-terminal Dscam_C PF12355.8 RJW64302.1 - 0.22 12.5 4.0 0.59 11.1 4.0 1.7 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal CAP_N PF01213.19 RJW64302.1 - 1.4 8.4 3.3 2.9 7.3 3.3 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SAYSvFN PF10260.9 RJW64303.1 - 6 6.9 6.6 1.9 8.5 0.1 3.2 3 1 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) zf-C2H2 PF00096.26 RJW64304.1 - 3e-22 77.8 55.6 3.7e-05 23.9 0.9 9.6 9 1 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW64304.1 - 3.3e-16 58.6 62.1 0.0037 18.0 1.0 10.5 9 1 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW64304.1 - 4.5e-09 36.3 53.0 0.00026 21.3 0.4 8.8 9 1 0 9 9 9 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW64304.1 - 0.00024 21.3 21.3 0.41 11.0 0.0 6.4 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 RJW64304.1 - 0.0008 20.0 0.1 0.0008 20.0 0.1 3.6 3 0 0 3 3 3 1 FOXP coiled-coil domain DUF2795 PF11387.8 RJW64304.1 - 0.0035 17.5 0.0 6.8 7.0 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2795) zf-C2H2_6 PF13912.6 RJW64304.1 - 0.0091 16.0 29.8 0.11 12.5 0.6 7.0 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 RJW64304.1 - 0.052 13.5 0.2 0.052 13.5 0.2 6.3 6 0 0 6 6 6 0 zinc-finger of a C2HC-type RVT_1 PF00078.27 RJW64304.1 - 0.079 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_7 PF02591.15 RJW64304.1 - 0.15 12.3 0.2 0.15 12.3 0.2 4.5 5 0 0 5 5 4 0 C4-type zinc ribbon domain Zn_ribbon_SprT PF17283.2 RJW64304.1 - 0.51 10.3 0.1 0.22 11.5 0.4 5.5 5 2 0 5 5 4 0 SprT-like zinc ribbon domain zf-C2H2_3rep PF18868.1 RJW64304.1 - 1.3 9.7 19.9 3.6 8.3 0.2 4.9 3 1 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 RJW64304.1 - 1.8 8.6 14.6 1.2 9.2 1.4 3.8 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2321 PF10083.9 RJW64304.1 - 1.8 8.2 8.0 2 8.0 0.3 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_2 PF12756.7 RJW64304.1 - 2.5 8.5 16.7 0.05 13.9 1.5 4.2 3 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) PAN_1 PF00024.26 RJW64305.1 - 0.00024 21.0 0.9 0.00049 20.0 0.9 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RJW64305.1 - 0.065 13.2 1.2 0.065 13.2 1.2 1.9 2 0 0 2 2 2 0 PAN domain Serpin PF00079.20 RJW64306.1 - 1.2e-16 61.1 0.0 1.4e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Melibiase_2 PF16499.5 RJW64307.1 - 1.1e-123 411.9 1.2 1.3e-123 411.7 1.2 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 RJW64307.1 - 5.2e-08 33.0 0.0 8.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 RJW64307.1 - 1.9e-06 27.1 0.0 4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Melibiase Actin PF00022.19 RJW64308.1 - 5.2e-211 700.5 0.0 1.1e-112 376.7 0.0 3.5 2 2 0 2 2 2 2 Actin MreB_Mbl PF06723.13 RJW64308.1 - 0.0013 17.6 0.0 0.82 8.4 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein Acp26Ab PF05777.12 RJW64309.1 - 0.058 14.0 0.0 0.17 12.6 0.0 1.7 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) Tfb5 PF06331.12 RJW64310.1 - 2.4e-09 37.0 0.1 3.8e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Hydrolase_4 PF12146.8 RJW64311.1 - 5.7e-15 55.2 0.0 1.2e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RJW64311.1 - 4.6e-10 39.6 0.0 4.8e-06 26.4 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RJW64311.1 - 3.2e-08 34.5 0.1 4e-07 30.9 0.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.12 RJW64311.1 - 2e-05 23.7 0.0 3.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 RJW64311.1 - 0.0067 15.9 0.0 0.04 13.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 RJW64311.1 - 0.031 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1057 PF06342.12 RJW64311.1 - 0.23 10.4 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) VHL PF01847.16 RJW64312.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 VHL beta domain ABC_tran PF00005.27 RJW64313.1 - 6e-25 88.4 0.1 2.1e-23 83.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter ABC_tran_Xtn PF12848.7 RJW64313.1 - 2.2e-19 69.3 2.4 2.2e-19 69.3 2.4 2.7 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 RJW64313.1 - 4.7e-06 26.6 2.1 0.0094 15.8 0.1 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RJW64313.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 RJW64313.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 RJW64313.1 - 0.038 13.4 0.0 0.13 11.7 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 RJW64313.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 RJW64313.1 - 0.089 12.5 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 RJW64313.1 - 0.1 12.8 0.0 0.42 10.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RJW64313.1 - 0.13 12.3 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RJW64313.1 - 0.21 12.1 0.2 0.21 12.1 0.2 3.0 2 2 0 2 2 2 0 AAA domain DUF5517 PF17639.2 RJW64313.1 - 0.26 11.6 1.3 0.51 10.7 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5517) BUD22 PF09073.10 RJW64313.1 - 0.28 10.5 11.0 0.62 9.4 6.4 2.2 2 0 0 2 2 2 0 BUD22 DUF1151 PF06625.11 RJW64313.1 - 9.1 6.3 10.6 0.14 12.1 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1151) G-alpha PF00503.20 RJW64314.1 - 1.5e-77 261.1 16.5 7e-74 249.1 10.3 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 RJW64314.1 - 2.6e-14 53.0 1.7 7e-11 41.9 0.2 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW64314.1 - 2.7e-05 23.7 1.7 0.00013 21.4 0.1 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RJW64314.1 - 0.00095 19.2 0.5 0.33 11.0 0.0 3.1 2 2 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 RJW64314.1 - 0.0023 17.4 0.2 0.58 9.6 0.1 3.0 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Roc PF08477.13 RJW64314.1 - 0.013 15.8 0.1 1.5 9.0 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Inhibitor_I34 PF10466.9 RJW64314.1 - 0.027 15.0 0.7 0.49 11.0 0.0 2.6 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 AAA_29 PF13555.6 RJW64314.1 - 0.077 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 RJW64314.1 - 0.083 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 RJW64314.1 - 0.11 12.0 5.6 0.38 10.3 1.6 2.9 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 RJW64314.1 - 0.23 11.2 2.5 2 8.1 0.2 3.0 2 1 1 3 3 3 0 AAA domain AAA_15 PF13175.6 RJW64314.1 - 0.25 11.0 10.0 0.091 12.5 1.6 2.6 2 1 1 3 3 3 0 AAA ATPase domain EGF PF00008.27 RJW64315.1 - 0.0026 18.0 15.5 0.64 10.4 0.1 5.6 5 0 0 5 5 5 3 EGF-like domain EGF_2 PF07974.13 RJW64315.1 - 0.0078 16.6 17.2 0.014 15.8 0.0 4.5 4 1 0 4 4 4 2 EGF-like domain DSL PF01414.19 RJW64315.1 - 0.028 14.7 12.0 0.065 13.5 2.7 3.4 2 0 0 2 2 2 0 Delta serrate ligand PAN_1 PF00024.26 RJW64317.1 - 5.7e-05 23.0 0.8 0.00012 22.0 0.8 1.5 1 0 0 1 1 1 1 PAN domain RVT_1 PF00078.27 RJW64318.1 - 1.8e-46 158.4 0.3 5.5e-46 156.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C12 PF01088.21 RJW64318.1 - 1.7e-44 152.1 0.0 2.6e-39 135.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 RJW64318.1 - 4.3e-15 55.3 2.9 8.8e-15 54.3 2.9 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Exo_endo_phos_2 PF14529.6 RJW64318.1 - 3e-06 27.1 0.0 2.9e-05 23.9 0.0 2.7 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase Zf_RING PF16744.5 RJW64319.1 - 0.096 12.8 0.4 0.14 12.2 0.4 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger 7tm_1 PF00001.21 RJW64320.1 - 2.9e-06 26.8 18.2 9.3e-05 21.9 18.2 2.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CHCH PF06747.13 RJW64321.1 - 9.1e-07 28.9 0.5 3e-06 27.2 0.3 2.0 2 0 0 2 2 2 1 CHCH domain MTCP1 PF08991.10 RJW64321.1 - 0.00018 21.6 0.6 0.00082 19.5 0.4 2.2 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type TSC22 PF01166.18 RJW64322.1 - 0.00014 22.1 0.2 0.00014 22.1 0.2 3.7 2 1 2 4 4 4 1 TSC-22/dip/bun family DUF2968 PF11180.8 RJW64322.1 - 0.0012 18.6 7.3 0.0012 18.6 7.3 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2968) APG6_N PF17675.1 RJW64322.1 - 0.0061 17.1 15.8 0.037 14.6 11.3 2.7 2 1 0 2 2 2 1 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 RJW64322.1 - 0.0095 16.0 6.1 0.0095 16.0 6.1 3.2 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3086 PF11285.8 RJW64322.1 - 0.028 13.6 1.1 2.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Phage_GP20 PF06810.11 RJW64322.1 - 0.039 13.7 6.1 0.14 11.9 0.6 2.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 Med30 PF11315.8 RJW64322.1 - 0.044 14.0 10.9 0.028 14.6 7.3 2.3 2 1 0 2 2 2 0 Mediator complex subunit 30 MtlR PF05068.12 RJW64322.1 - 0.045 13.8 0.2 0.14 12.1 0.2 1.8 1 0 0 1 1 1 0 Mannitol repressor Spc7 PF08317.11 RJW64322.1 - 0.045 12.6 16.7 0.011 14.6 3.8 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein ERM PF00769.19 RJW64322.1 - 0.05 13.4 14.2 0.012 15.4 8.4 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family zf-RING_9 PF13901.6 RJW64322.1 - 0.053 13.5 4.2 1.3 8.9 0.6 2.4 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon DUF3584 PF12128.8 RJW64322.1 - 0.059 10.9 18.0 0.0026 15.4 11.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) SLATT_4 PF18186.1 RJW64322.1 - 0.082 12.5 3.7 0.07 12.8 1.0 2.2 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 zf-C4H2 PF10146.9 RJW64322.1 - 0.14 12.5 14.8 0.13 12.5 7.4 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein Golgin_A5 PF09787.9 RJW64322.1 - 0.16 11.4 17.4 0.1 12.1 3.0 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 GAS PF13851.6 RJW64322.1 - 0.18 11.1 13.7 2.6 7.4 9.7 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 RJW64322.1 - 0.19 12.0 11.2 0.3 11.3 4.3 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.11 RJW64322.1 - 0.28 11.3 10.5 0.17 12.0 0.3 3.1 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase LPP PF04728.13 RJW64322.1 - 0.31 11.5 9.7 4.2 7.9 0.0 4.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.7 RJW64322.1 - 0.42 10.7 17.7 0.28 11.3 13.8 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.12 RJW64322.1 - 0.44 10.6 13.6 2.1 8.4 1.9 3.5 3 1 1 4 4 3 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 RJW64322.1 - 0.63 11.0 15.6 5.8 7.9 4.7 3.5 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Vps54_N PF10475.9 RJW64322.1 - 0.67 9.2 6.7 0.59 9.4 0.1 2.5 2 1 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex JIP_LZII PF16471.5 RJW64322.1 - 0.78 10.0 11.2 0.97 9.7 1.6 3.7 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II DASH_Dam1 PF08653.10 RJW64322.1 - 0.79 9.6 3.0 6.2 6.7 0.7 2.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 TPR_MLP1_2 PF07926.12 RJW64322.1 - 0.82 9.7 20.9 0.55 10.3 11.5 3.4 3 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 RJW64322.1 - 0.84 10.1 6.3 0.83 10.2 0.1 3.4 3 2 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Tho2 PF11262.8 RJW64322.1 - 1.1 8.4 5.2 1.3 8.1 1.0 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 CENP-H PF05837.12 RJW64322.1 - 1.2 9.5 19.4 2.8 8.4 7.3 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) BLOC1_2 PF10046.9 RJW64322.1 - 1.4 9.2 7.2 0.57 10.5 0.3 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mt_ATP-synt_B PF05405.14 RJW64322.1 - 2.3 7.8 7.7 12 5.4 3.8 2.6 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RasGAP_C PF03836.15 RJW64322.1 - 2.4 8.3 9.1 0.16 12.1 1.5 2.6 2 1 1 3 3 3 0 RasGAP C-terminus YabA PF06156.13 RJW64322.1 - 2.7 8.7 8.7 6 7.6 2.0 3.2 2 1 1 3 3 3 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 RJW64322.1 - 2.9 8.0 12.0 9 6.4 0.2 3.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 RJW64322.1 - 3.5 6.1 8.7 2.6 6.5 5.5 2.3 2 1 0 2 2 2 0 Flagellar Assembly Protein A BST2 PF16716.5 RJW64322.1 - 3.5 8.3 14.7 3 8.5 1.1 3.5 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Fmp27_WPPW PF10359.9 RJW64322.1 - 3.7 6.3 15.9 0.1 11.5 6.6 2.3 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain ZapB PF06005.12 RJW64322.1 - 3.8 8.0 16.2 10 6.7 4.9 3.5 2 1 1 3 3 3 0 Cell division protein ZapB STAT_alpha PF01017.20 RJW64322.1 - 4.1 7.3 10.3 5.5 6.9 6.2 2.3 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF1043 PF06295.12 RJW64322.1 - 4.2 7.4 13.7 0.79 9.7 2.4 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1043) AAA_11 PF13086.6 RJW64322.1 - 4.3 7.0 13.3 0.97 9.2 9.2 1.8 1 1 1 2 2 2 0 AAA domain ATG16 PF08614.11 RJW64322.1 - 4.5 7.5 30.6 0.47 10.7 15.6 3.1 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 RJW64322.1 - 4.7 7.6 18.6 1.6 9.2 12.2 2.5 1 1 1 3 3 3 0 Fez1 Cep57_CLD_2 PF14197.6 RJW64322.1 - 9.2 6.4 15.1 7.7 6.7 5.8 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF1759 PF03564.15 RJW64323.1 - 0.016 15.1 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) RVT_1 PF00078.27 RJW64324.1 - 7e-23 81.3 0.0 1.2e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rubredoxin PF00301.20 RJW64325.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Rubredoxin Ras PF00071.22 RJW64326.1 - 6.8e-31 107.1 0.0 8.3e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW64326.1 - 0.00026 21.2 0.0 0.00046 20.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW64326.1 - 0.12 11.8 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family 7tm_1 PF00001.21 RJW64327.1 - 7.4e-14 51.7 7.1 9.8e-14 51.3 7.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cyt_c_ox_IV PF12270.8 RJW64327.1 - 0.0019 18.3 0.3 0.0019 18.3 0.3 2.7 3 1 1 4 4 4 1 Cytochrome c oxidase subunit IV Ku PF02735.16 RJW64328.1 - 1.6e-42 145.5 0.0 3e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 RJW64328.1 - 2.6e-30 105.8 0.0 3.9e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Peptidase_S9 PF00326.21 RJW64328.1 - 1.2e-28 100.0 0.0 2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ku_C PF03730.14 RJW64328.1 - 7.7e-14 52.2 0.1 1.7e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Hydrolase_4 PF12146.8 RJW64328.1 - 5.3e-08 32.4 0.0 7.6e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RJW64328.1 - 8.7e-08 32.1 0.1 2e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PD40 PF07676.12 RJW64328.1 - 1.8e-05 24.6 1.1 0.04 13.9 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.7 RJW64328.1 - 2.3e-05 25.1 1.5 6.4e-05 23.7 1.5 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 RJW64328.1 - 0.037 13.7 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Baculo_LEF5_C PF11792.8 RJW64328.1 - 0.042 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DUF2920 PF11144.8 RJW64328.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) ELL PF10390.9 RJW64328.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL HSP90 PF00183.18 RJW64329.1 - 3.1e-95 320.1 0.0 1.7e-92 311.0 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 RJW64329.1 - 2.8e-10 40.2 0.1 5e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RJW64329.1 - 3.6e-07 30.7 0.2 6.6e-07 29.8 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YbjN PF10722.9 RJW64329.1 - 0.19 11.8 0.1 31 4.6 0.0 2.6 2 1 0 2 2 2 0 Putative bacterial sensory transduction regulator Actin PF00022.19 RJW64330.1 - 4.2e-101 338.5 0.0 1e-99 333.9 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RJW64330.1 - 2.2e-06 26.8 0.0 1.5e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Ribosomal_L7Ae PF01248.26 RJW64331.1 - 6.1e-06 25.9 0.1 2.2e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-C2H2_4 PF13894.6 RJW64332.1 - 6.1e-08 32.9 53.2 0.066 14.1 0.4 10.1 10 0 0 10 10 10 4 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW64332.1 - 2.8e-06 27.4 57.3 0.0042 17.5 0.8 10.1 10 0 0 10 10 10 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW64332.1 - 9.5e-06 25.8 3.8 0.00015 22.0 1.7 8.6 9 0 0 9 9 8 3 Zinc-finger double domain FOXP-CC PF16159.5 RJW64332.1 - 0.00074 20.1 28.3 2.6 8.8 0.2 7.5 5 1 2 7 7 7 2 FOXP coiled-coil domain zf-Di19 PF05605.12 RJW64332.1 - 0.004 17.4 28.8 0.011 16.0 4.4 6.3 6 1 1 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 RJW64332.1 - 0.025 15.0 33.2 0.28 11.7 0.6 6.2 4 1 1 5 5 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 RJW64332.1 - 0.026 14.2 5.1 9.6 5.9 0.1 4.5 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2321 PF10083.9 RJW64332.1 - 0.077 12.6 0.3 0.077 12.6 0.3 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Zap1_zf2 PF18217.1 RJW64332.1 - 0.19 11.7 14.7 0.12 12.4 0.7 3.7 3 0 0 3 3 3 0 Zap1 zinc finger 2 Zn-C2H2_12 PF18112.1 RJW64332.1 - 0.24 11.9 8.4 5.5 7.6 0.0 5.0 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 RJW64332.1 - 0.28 11.1 10.3 37 4.3 0.0 5.9 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 RJW64332.1 - 0.42 10.4 0.1 0.046 13.5 1.4 6.4 8 0 0 8 8 8 0 C2H2-type zinc-finger domain SIR2 PF02146.17 RJW64332.1 - 0.76 9.7 2.6 1.7 8.5 2.1 1.9 1 1 0 1 1 1 0 Sir2 family zf-Nse PF11789.8 RJW64332.1 - 4.8 7.1 6.9 2.7 7.9 3.2 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Serinc PF03348.15 RJW64333.1 - 1.4e-147 492.1 21.5 1.6e-147 491.9 21.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) zf-H2C2_2 PF13465.6 RJW64334.1 - 6.5e-11 42.1 19.1 1.8e-05 24.9 3.5 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 RJW64334.1 - 2.3e-09 37.2 28.0 0.00023 21.4 1.6 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW64334.1 - 6.4e-06 26.6 24.0 0.0083 16.9 1.3 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RJW64334.1 - 0.0017 18.0 2.4 0.0017 18.0 2.4 3.4 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 RJW64334.1 - 0.048 13.6 2.4 0.054 13.4 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 RJW64334.1 - 0.17 12.4 3.1 2 9.0 0.1 3.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 RJW64334.1 - 0.82 9.7 10.6 3.2 7.8 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2225 PF09986.9 RJW64334.1 - 0.97 9.1 2.8 17 5.0 0.2 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.8 RJW64334.1 - 1.5 9.2 7.1 2.3 8.6 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SF3b1 PF08920.10 RJW64336.1 - 5.8e-39 133.2 46.5 2e-37 128.3 15.0 5.7 2 2 1 3 3 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 RJW64336.1 - 1.5e-10 41.3 2.2 0.29 11.5 0.0 7.5 5 2 2 7 7 7 2 HEAT repeats HEAT PF02985.22 RJW64336.1 - 1.5e-09 37.3 4.5 0.69 10.3 0.1 7.9 9 0 0 9 9 8 2 HEAT repeat HEAT_EZ PF13513.6 RJW64336.1 - 4.8e-07 30.1 8.3 0.83 10.2 0.0 7.7 9 1 1 10 10 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 RJW64336.1 - 4.8e-06 27.1 1.4 1.5 9.5 0.0 4.9 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RJW64336.1 - 1.5e-05 25.1 6.8 2.5 8.1 0.0 6.9 6 1 1 8 8 8 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 RJW64336.1 - 0.00032 20.3 0.8 3.8 7.0 0.1 3.4 3 0 0 3 3 3 2 CLASP N terminal DUF3385 PF11865.8 RJW64336.1 - 0.0004 20.3 3.8 0.56 10.1 0.1 4.8 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) UME PF08064.13 RJW64336.1 - 0.00043 20.2 0.9 4.8 7.1 0.1 5.4 6 1 0 6 6 6 1 UME (NUC010) domain IFRD PF05004.13 RJW64336.1 - 0.0012 18.0 0.3 1.1 8.3 0.0 3.4 3 1 1 4 4 4 1 Interferon-related developmental regulator (IFRD) NUC173 PF08161.12 RJW64336.1 - 0.0078 15.9 0.5 2.3 7.8 0.0 4.2 4 2 0 5 5 5 1 NUC173 domain Adaptin_N PF01602.20 RJW64336.1 - 0.018 13.6 2.3 0.17 10.4 1.9 2.8 1 1 0 1 1 1 0 Adaptin N terminal region TIP120 PF08623.10 RJW64336.1 - 0.046 13.5 0.2 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DRIM PF07539.12 RJW64336.1 - 0.12 10.7 0.2 18 3.5 0.0 3.2 2 1 0 3 3 3 0 Down-regulated in metastasis DNA_pol_phi PF04931.13 RJW64336.1 - 0.17 9.9 0.0 6.5 4.7 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase phi DUF688 PF05097.12 RJW64336.1 - 0.21 10.7 1.4 0.32 10.1 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Hydrolase_4 PF12146.8 RJW64339.1 - 1.8e-14 53.6 0.0 4.2e-09 36.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RJW64339.1 - 3.8e-07 30.9 0.0 1.4e-06 29.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RJW64339.1 - 2.1e-06 27.5 0.0 0.0051 16.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 RJW64339.1 - 2.1e-05 23.7 0.0 2.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 RJW64339.1 - 0.00049 19.6 0.0 0.0075 15.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 RJW64339.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 RJW64339.1 - 0.19 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF1571 PF07608.11 RJW64340.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) TPR_1 PF00515.28 RJW64341.1 - 5.3e-29 98.8 14.6 2.7e-05 23.8 0.3 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 RJW64341.1 - 1.1e-25 87.6 16.8 0.00027 20.8 0.4 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_9 PF13371.6 RJW64341.1 - 6.5e-13 48.6 6.4 2e-06 27.8 0.7 4.2 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 RJW64341.1 - 2.7e-11 43.6 14.6 0.0057 16.9 0.2 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 RJW64341.1 - 3.5e-11 42.4 7.4 0.24 11.7 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW64341.1 - 3.5e-11 43.4 11.9 3.9e-05 24.1 2.4 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 RJW64341.1 - 1.9e-10 41.2 9.7 0.00069 20.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW64341.1 - 6.7e-09 35.8 8.8 0.87 10.6 0.2 7.0 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 RJW64341.1 - 4.6e-08 32.6 10.6 0.13 11.9 0.4 5.1 5 0 0 5 5 5 3 TPR repeat RPAP3_C PF13877.6 RJW64341.1 - 1.2e-07 32.1 0.3 7.2e-07 29.7 0.0 2.5 3 0 0 3 3 1 1 Potential Monad-binding region of RPAP3 TPR_6 PF13174.6 RJW64341.1 - 7.7e-06 26.2 9.8 0.46 11.2 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW64341.1 - 0.00011 21.9 5.0 6.3 7.1 0.1 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW64341.1 - 0.00024 21.3 7.4 0.051 13.8 2.7 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 RJW64341.1 - 0.014 15.4 14.6 0.32 11.1 0.5 5.5 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 RJW64341.1 - 0.015 15.6 15.4 5.3 7.6 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L5 PF00281.19 RJW64341.1 - 0.051 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein L5 Rap1a PF18602.1 RJW64341.1 - 0.058 13.7 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Rap1a immunity proteins MIT PF04212.18 RJW64341.1 - 0.059 13.4 6.6 1.3 9.1 0.2 4.3 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain FeoB_Cyto PF17910.1 RJW64341.1 - 0.25 11.9 1.9 9.9 6.8 0.2 3.9 3 0 0 3 3 3 0 FeoB cytosolic helical domain TPR_MalT PF17874.1 RJW64341.1 - 0.35 10.2 6.5 2.4 7.5 0.1 3.0 2 1 1 3 3 3 0 MalT-like TPR region EGF PF00008.27 RJW64342.1 - 0.0069 16.7 20.5 1.9 8.8 2.0 6.0 5 0 0 5 5 5 2 EGF-like domain DUF4722 PF15849.5 RJW64342.1 - 0.022 14.5 0.7 0.98 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4722) DSL PF01414.19 RJW64342.1 - 0.039 14.2 16.5 0.081 13.2 8.1 3.7 2 1 1 3 3 3 0 Delta serrate ligand Laminin_EGF PF00053.24 RJW64342.1 - 0.32 11.2 23.0 0.33 11.1 2.5 4.7 4 0 0 4 4 4 0 Laminin EGF domain EGF_2 PF07974.13 RJW64342.1 - 5.5 7.5 26.3 0.28 11.6 2.0 4.8 4 1 0 4 4 4 0 EGF-like domain Cullin PF00888.22 RJW64344.1 - 2.2e-129 432.9 2.8 3.7e-129 432.2 2.8 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RJW64344.1 - 9.4e-25 86.4 0.7 3e-24 84.8 0.1 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.11 RJW64344.1 - 0.084 12.9 0.3 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 HbrB-like GNT-I PF03071.15 RJW64345.1 - 8.6e-113 377.3 0.0 1.2e-112 376.9 0.0 1.1 1 0 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 RJW64345.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase like family 2 MIEAP PF16026.5 RJW64346.1 - 4.7e-42 144.5 1.0 1.5e-41 142.8 0.0 2.0 2 0 0 2 2 2 1 Mitochondria-eating protein BAR PF03114.18 RJW64346.1 - 0.0021 17.7 0.4 0.042 13.5 0.2 2.2 2 0 0 2 2 2 1 BAR domain KIAA1430 PF13879.6 RJW64346.1 - 0.0047 17.7 1.9 0.0047 17.7 1.9 2.1 2 0 0 2 2 2 1 KIAA1430 homologue Syntaxin PF00804.25 RJW64346.1 - 0.0049 16.6 5.4 0.13 12.0 0.1 2.4 2 0 0 2 2 2 2 Syntaxin Tropomyosin_1 PF12718.7 RJW64346.1 - 0.016 15.4 4.7 0.035 14.3 4.7 1.5 1 0 0 1 1 1 0 Tropomyosin like DUF1465 PF07323.12 RJW64346.1 - 0.03 14.1 2.9 0.078 12.8 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) UPF0242 PF06785.11 RJW64346.1 - 0.056 13.6 3.7 0.099 12.7 3.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_2 PF07716.15 RJW64346.1 - 0.07 13.2 3.3 0.23 11.6 3.3 1.9 1 0 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.18 RJW64346.1 - 0.071 13.3 2.8 0.2 11.9 2.8 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4349 PF14257.6 RJW64346.1 - 0.082 12.3 0.5 0.15 11.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Phage_GPO PF05929.11 RJW64346.1 - 0.14 11.7 5.5 0.24 11.0 5.5 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MAD PF05557.13 RJW64346.1 - 0.19 10.1 7.7 0.51 8.6 4.1 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein Peptidase_S28 PF05577.12 RJW64348.1 - 7.9e-83 278.7 0.0 9.4e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 RJW64348.1 - 0.0001 21.6 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RJW64348.1 - 0.00016 21.4 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RJW64348.1 - 0.00038 20.0 0.1 0.00069 19.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RJW64348.1 - 0.0006 20.5 0.0 0.0066 17.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.8 RJW64348.1 - 0.0041 16.3 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S37 PF05576.11 RJW64348.1 - 0.024 13.3 0.4 0.18 10.4 0.1 2.0 2 0 0 2 2 2 0 PS-10 peptidase S37 Cadherin PF00028.17 RJW64349.1 - 1.5e-56 188.8 2.5 1.4e-21 76.8 0.8 8.8 7 2 1 8 8 8 6 Cadherin domain Cadherin_pro PF08758.11 RJW64349.1 - 9.1e-06 25.8 0.1 0.0042 17.2 0.2 3.2 3 0 0 3 3 3 1 Cadherin prodomain like Cadherin_3 PF16184.5 RJW64349.1 - 4e-05 23.6 7.1 3.6 7.6 0.1 5.7 6 0 0 6 6 6 3 Cadherin-like Cadherin_2 PF08266.12 RJW64349.1 - 0.00047 19.9 0.0 1 9.3 0.0 3.8 3 0 0 3 3 3 1 Cadherin-like Big_1 PF02369.16 RJW64349.1 - 9 6.4 7.6 1.3e+02 2.7 1.1 4.5 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 1) Retinin_C PF04527.12 RJW64350.1 - 0.09 13.0 1.5 0.14 12.4 1.5 1.3 1 1 0 1 1 1 0 Drosophila Retinin like protein Pkinase PF00069.25 RJW64351.1 - 9.1e-40 136.7 0.0 2e-23 83.1 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64351.1 - 7.9e-15 54.8 0.0 2.6e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RJW64351.1 - 0.042 13.8 0.4 1.3 8.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 RJW64351.1 - 0.055 12.8 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 RJW64351.1 - 0.13 11.8 0.1 2.2 7.9 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Stap_Strp_tox_C PF02876.17 RJW64352.1 - 0.018 15.3 0.2 0.086 13.2 0.2 2.2 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Fez1 PF06818.15 RJW64352.1 - 6.4 7.2 80.0 1.6 9.1 6.3 5.5 2 1 3 5 5 5 0 Fez1 WAC_Acf1_DNA_bd PF10537.9 RJW64353.1 - 2.1e-24 85.9 0.0 5.8e-24 84.5 0.0 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.29 RJW64353.1 - 2.8e-23 81.6 17.5 1.8e-13 50.2 3.4 2.7 2 0 0 2 2 2 2 PHD-finger WSD PF15613.6 RJW64353.1 - 9.3e-17 61.3 1.1 5e-16 59.0 0.1 2.9 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Bromodomain PF00439.25 RJW64353.1 - 1.7e-15 56.9 0.0 4.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 RJW64353.1 - 1.6e-05 24.3 8.7 0.034 13.7 0.4 3.0 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 RJW64353.1 - 0.0015 18.8 7.5 0.24 11.7 0.6 2.7 2 0 0 2 2 2 2 PHD-like zinc-binding domain Zf_RING PF16744.5 RJW64353.1 - 0.005 16.9 8.8 0.43 10.7 1.0 3.0 2 0 0 2 2 2 2 KIAA1045 RING finger zf-RING_2 PF13639.6 RJW64353.1 - 0.0094 16.3 25.1 0.019 15.3 6.8 2.8 2 0 0 2 2 2 1 Ring finger domain zf-PHD-like PF15446.6 RJW64353.1 - 0.028 14.1 12.6 0.16 11.6 0.6 4.1 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H_2 PF13832.6 RJW64353.1 - 0.09 12.9 8.3 0.33 11.1 0.8 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 RJW64353.1 - 0.13 12.2 16.3 1.4 8.9 1.9 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 RJW64353.1 - 0.38 10.7 14.2 0.028 14.3 2.6 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DDT PF02791.17 RJW64353.1 - 0.91 9.9 4.4 6.1 7.2 2.2 2.9 2 1 0 2 2 2 0 DDT domain zf-rbx1 PF12678.7 RJW64353.1 - 4.9 7.5 16.5 0.64 10.3 5.5 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-Di19 PF05605.12 RJW64356.1 - 6.3e-05 23.2 24.4 0.00062 20.0 0.1 4.3 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 RJW64356.1 - 6.8e-05 23.4 52.0 0.0017 19.1 0.5 7.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-met PF12874.7 RJW64356.1 - 0.00031 21.0 0.9 0.00031 21.0 0.9 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 RJW64356.1 - 0.0004 20.6 16.0 0.1 12.9 0.2 4.0 4 0 0 4 4 4 2 C2H2-type zinc ribbon zf-C2H2 PF00096.26 RJW64356.1 - 0.00049 20.4 8.7 0.011 16.1 0.5 6.9 7 0 0 7 7 6 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW64356.1 - 0.0045 17.2 0.3 0.0045 17.2 0.3 3.9 4 0 0 4 4 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RJW64356.1 - 0.032 14.0 0.3 0.032 14.0 0.3 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RJW64356.1 - 0.032 14.7 0.7 0.032 14.7 0.7 6.6 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 RJW64356.1 - 0.21 11.4 0.2 0.21 11.4 0.2 3.2 4 0 0 4 4 3 0 zinc-finger C2H2-type DUF4428 PF14471.6 RJW64356.1 - 0.84 9.6 4.6 0.87 9.6 1.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C2H2_3rep PF18868.1 RJW64356.1 - 0.95 10.2 6.5 14 6.4 0.0 3.7 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-MYST PF17772.1 RJW64356.1 - 1.6 8.4 12.3 11 5.7 0.1 4.3 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 RJW64356.1 - 2.2 8.7 16.5 4.4 7.7 0.2 5.0 4 3 0 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RJW64356.1 - 2.7 8.2 16.4 0.14 12.3 0.5 4.6 3 1 2 5 5 5 0 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 RJW64356.1 - 4 7.1 11.2 0.24 11.1 3.1 2.8 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain F5_F8_type_C PF00754.25 RJW64358.1 - 0.04 14.0 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain Skp1 PF01466.19 RJW64359.1 - 2.9e-28 97.7 1.4 5.1e-28 96.9 1.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 RJW64359.1 - 1.1e-09 38.3 0.0 2.9e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain zf-RING_UBOX PF13445.6 RJW64361.1 - 6.8e-06 26.0 17.9 6.2e-05 22.9 11.8 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RJW64361.1 - 8.2e-06 25.6 14.6 0.0005 19.9 12.0 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW64361.1 - 0.00015 22.1 17.8 0.0096 16.2 13.5 2.7 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 RJW64361.1 - 0.00051 19.9 17.9 0.0052 16.6 12.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW64361.1 - 0.00062 19.6 15.4 0.023 14.6 10.4 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Peptidase_S7 PF00949.21 RJW64361.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease zf-C3HC4_4 PF15227.6 RJW64361.1 - 0.8 9.9 16.4 1.7 8.8 11.5 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RJW64361.1 - 1.6 8.7 17.7 1.6 8.6 0.3 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RJW64361.1 - 2.7 8.0 19.4 98 3.0 19.8 2.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 RJW64361.1 - 2.9 8.2 15.8 8 6.8 0.1 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain UCH PF00443.29 RJW64362.1 - 1.7e-31 109.7 0.0 2.6e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW64362.1 - 9.1e-17 61.6 1.7 1.1e-15 58.0 1.7 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glycos_transf_1 PF00534.20 RJW64363.1 - 1.3e-26 93.2 0.0 2.4e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RJW64363.1 - 8.4e-11 42.4 0.0 1.4e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RJW64363.1 - 9.6e-08 32.2 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_5 PF16994.5 RJW64363.1 - 0.041 13.5 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl-transferase family 4 BTK PF00779.19 RJW64363.1 - 0.25 11.2 2.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 BTK motif COE1_DBD PF16422.5 RJW64364.1 - 1.6e-121 404.1 5.0 2.4e-121 403.5 5.0 1.2 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 RJW64364.1 - 4.7e-29 99.8 0.6 8.4e-29 99.0 0.6 1.4 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 RJW64364.1 - 1.7e-11 44.1 0.0 3.5e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain DUF724 PF05266.14 RJW64365.1 - 0.0054 16.6 18.5 0.0054 16.6 18.5 5.2 3 2 3 6 6 6 1 Protein of unknown function (DUF724) HTH_37 PF13744.6 RJW64365.1 - 0.03 14.3 0.3 0.03 14.3 0.3 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1192 PF06698.11 RJW64365.1 - 0.28 11.3 9.2 0.36 10.9 0.1 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) zf-RING_2 PF13639.6 RJW64367.1 - 0.00038 20.7 1.1 0.00038 20.7 1.1 4.3 4 0 0 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 RJW64367.1 - 0.00041 20.1 0.6 0.00041 20.1 0.6 3.5 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RJW64367.1 - 0.007 16.4 0.2 0.038 14.0 0.2 2.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RJW64367.1 - 0.051 13.5 0.1 0.051 13.5 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW64367.1 - 0.18 11.7 0.0 0.18 11.7 0.0 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 RJW64370.1 - 2.5e-17 62.3 23.9 0.00056 20.2 0.8 6.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW64370.1 - 3.7e-11 42.9 34.3 2.4e-07 30.9 0.4 6.4 7 0 0 7 7 7 3 Zinc-finger double domain FOXP-CC PF16159.5 RJW64370.1 - 3.3e-05 24.4 20.5 0.00062 20.3 1.8 5.1 4 2 1 5 5 5 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 RJW64370.1 - 0.0089 16.8 35.4 0.0093 16.7 0.6 6.7 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RJW64370.1 - 0.034 14.3 10.2 0.58 10.3 0.2 3.9 2 1 1 3 3 3 0 Aberrant zinc-finger zf_ZIC PF18366.1 RJW64370.1 - 0.26 11.4 3.7 0.36 11.0 0.0 3.0 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 RJW64370.1 - 7.4 7.0 11.4 4.5 7.6 0.7 3.6 2 1 1 3 3 3 0 C2H2-type zinc ribbon Peptidase_M60 PF13402.6 RJW64371.1 - 6.5e-20 71.8 2.8 3.8e-19 69.3 2.8 2.0 1 1 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 RJW64371.1 - 9.7e-07 28.7 0.1 2.4e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases F5_F8_type_C PF00754.25 RJW64371.1 - 0.00016 21.8 0.1 0.00061 19.9 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain DUF498 PF04430.14 RJW64372.1 - 1.8e-14 53.7 0.0 3.7e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) UMP1 PF05348.11 RJW64375.1 - 7.6e-13 48.7 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 RVT_1 PF00078.27 RJW64375.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 RJW64376.1 - 0.012 16.2 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 RJW64376.1 - 0.021 15.4 0.0 0.033 14.7 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 RJW64376.1 - 0.023 14.7 3.4 0.091 12.9 3.4 2.1 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 RJW64376.1 - 0.033 14.0 0.2 0.069 12.9 0.1 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_5 PF14787.6 RJW64376.1 - 4 7.2 8.9 10 5.9 2.4 2.5 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger Sortilin-Vps10 PF15902.5 RJW64377.1 - 1.4e-64 218.6 0.1 2.8e-34 118.7 0.2 2.4 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 RJW64377.1 - 9.7e-31 107.4 0.0 1.5e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 RJW64377.1 - 3.9e-10 38.2 19.5 0.17 12.0 0.1 7.1 6 0 0 6 6 6 6 BNR/Asp-box repeat BNR_6 PF15899.5 RJW64377.1 - 0.028 14.5 2.4 1.5e+02 2.9 0.1 5.2 5 0 0 5 5 5 0 BNR-Asp box repeat RVT_1 PF00078.27 RJW64378.1 - 3e-40 138.1 0.0 5.1e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) His_Phos_1 PF00300.22 RJW64378.1 - 4e-08 33.2 0.0 3.2e-05 23.7 0.0 2.8 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Exo_endo_phos_2 PF14529.6 RJW64378.1 - 5e-07 29.6 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW64378.1 - 0.0036 16.9 0.1 0.012 15.2 0.1 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_34 PF13872.6 RJW64379.1 - 3.1e-138 459.8 0.0 4.4e-138 459.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 RJW64379.1 - 1.5e-115 385.5 0.7 2.3e-115 384.9 0.7 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 RJW64379.1 - 2.9e-05 24.1 0.0 5.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RJW64379.1 - 0.17 12.2 0.1 0.46 10.9 0.1 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain NOA36 PF06524.12 RJW64379.1 - 0.79 9.0 4.0 2 7.7 4.0 1.7 1 0 0 1 1 1 0 NOA36 protein UQ_con PF00179.26 RJW64380.1 - 1.6e-44 151.0 0.0 1.8e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RJW64380.1 - 0.0059 16.3 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B S1 PF00575.23 RJW64382.1 - 1.2e-14 54.4 0.0 1.9e-05 24.9 0.0 5.8 6 0 0 6 6 6 5 S1 RNA binding domain Sod_Cu PF00080.20 RJW64384.1 - 1.4e-38 132.2 1.6 2.1e-38 131.7 1.6 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMG_box PF00505.19 RJW64385.1 - 5.2e-37 126.1 16.7 5.4e-21 74.8 4.7 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW64385.1 - 1.3e-29 102.6 19.1 1.6e-17 63.9 5.6 2.1 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 RJW64385.1 - 0.012 15.6 2.5 0.012 15.6 2.5 2.4 2 1 0 2 2 2 0 HMG (high mobility group) box 5 MEIOC PF15189.6 RJW64385.1 - 0.9 9.1 7.0 1.3 8.6 1.0 2.2 2 0 0 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC FTCD_C PF04961.12 RJW64385.1 - 1.2 8.8 5.6 0.21 11.3 1.7 1.6 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase YABBY PF04690.13 RJW64385.1 - 2 8.9 7.9 0.65 10.5 5.0 1.6 1 1 1 2 2 2 0 YABBY protein CUB PF00431.20 RJW64386.1 - 0.0017 18.7 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 CUB domain HAT_KAT11 PF08214.11 RJW64387.1 - 5.7e-65 219.9 0.0 1.3e-64 218.8 0.0 1.6 1 0 0 1 1 1 1 Histone acetylation protein zf-TAZ PF02135.16 RJW64387.1 - 2.2e-25 88.9 65.4 5.6e-18 65.2 17.1 3.9 3 0 0 3 3 3 2 TAZ zinc finger KIX PF02172.16 RJW64387.1 - 1.3e-24 86.3 0.3 1.3e-24 86.3 0.3 2.0 2 0 0 2 2 2 1 KIX domain Bromodomain PF00439.25 RJW64387.1 - 7.7e-21 74.0 3.6 1.5e-20 73.1 0.5 2.5 2 0 0 2 2 2 1 Bromodomain DUF902 PF06001.13 RJW64387.1 - 4.6e-17 62.2 4.2 9.8e-17 61.2 4.2 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) ZZ PF00569.17 RJW64387.1 - 5.3e-12 45.3 8.8 5.3e-12 45.3 8.8 3.8 4 0 0 4 4 4 1 Zinc finger, ZZ type SRP-alpha_N PF04086.13 RJW64387.1 - 0.00075 19.5 0.5 0.00075 19.5 0.5 3.0 3 0 0 3 3 3 1 Signal recognition particle, alpha subunit, N-terminal KIX_2 PF16987.5 RJW64387.1 - 0.0067 16.4 0.1 0.019 14.9 0.1 1.8 1 0 0 1 1 1 1 KIX domain CSTF2_hinge PF14327.6 RJW64388.1 - 9.4e-31 106.1 4.2 2e-30 105.1 4.2 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 RJW64388.1 - 1e-21 76.5 0.0 1.7e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 RJW64388.1 - 1.2e-19 69.6 7.6 4.5e-19 67.7 5.3 2.4 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 RJW64388.1 - 0.2 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RVT_1 PF00078.27 RJW64390.1 - 3.4e-05 23.5 0.0 4.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ubiq_cyt_C_chap PF03981.12 RJW64391.1 - 8.9e-32 110.1 0.0 1.3e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone COX2-transmemb PF09125.10 RJW64391.1 - 0.12 12.2 0.3 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane DEP PF00610.21 RJW64393.1 - 1.9e-06 27.8 0.0 3.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Yip1 PF04893.17 RJW64395.1 - 6e-08 32.6 12.8 9.3e-08 32.0 12.8 1.3 1 0 0 1 1 1 1 Yip1 domain LRR_8 PF13855.6 RJW64396.1 - 1.4e-60 200.9 131.8 1.5e-10 40.7 1.2 9.1 3 3 9 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 RJW64396.1 - 4.1e-40 135.1 91.7 2.3e-06 27.8 4.7 11.3 6 2 6 12 12 12 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW64396.1 - 6e-07 29.1 41.4 0.024 14.1 2.3 6.3 1 1 5 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 RJW64396.1 - 4.7e-05 23.4 88.4 0.3 11.8 1.1 17.7 18 2 1 19 19 19 6 Leucine Rich Repeat LRR_5 PF13306.6 RJW64396.1 - 9e-05 22.4 11.8 0.0068 16.4 3.5 4.1 4 1 1 5 5 5 2 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 RJW64396.1 - 0.0021 18.0 6.4 19 5.4 0.1 6.9 7 3 2 9 9 9 1 RsmF rRNA methyltransferase first C-terminal domain zf_Hakai PF18408.1 RJW64397.1 - 2.7e-17 62.2 2.3 2.7e-17 62.2 2.3 2.2 2 0 0 2 2 2 1 C2H2 Hakai zinc finger domain zf-C3HC4_3 PF13920.6 RJW64397.1 - 0.0003 20.6 9.0 0.00061 19.6 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RJW64397.1 - 0.0037 17.1 2.9 0.0087 15.9 2.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RJW64397.1 - 0.02 14.9 8.7 0.05 13.6 8.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 RJW64397.1 - 0.05 13.5 8.5 0.13 12.1 8.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 RJW64397.1 - 3.1 7.9 9.9 17 5.5 9.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 RJW64397.1 - 4.7 7.1 10.3 17 5.4 9.7 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 RJW64397.1 - 6.8 6.8 11.2 12 5.9 11.2 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-RING_2 PF13639.6 RJW64397.1 - 8.4 6.8 9.6 19 5.7 9.6 1.7 1 0 0 1 1 1 0 Ring finger domain GTP_cyclohydroI PF01227.22 RJW64399.1 - 2e-70 235.9 0.3 2.8e-70 235.4 0.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 RJW64399.1 - 0.0046 17.1 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DUF3883 PF13020.6 RJW64400.1 - 4.9e-05 23.3 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) FYRC PF05965.14 RJW64402.1 - 8.8e-25 86.7 0.0 3.6e-24 84.7 0.0 2.1 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.14 RJW64402.1 - 9.7e-22 76.6 1.8 2.9e-21 75.0 1.8 1.9 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 RJW64402.1 - 2.4e-16 60.6 1.7 6.1e-16 59.3 0.7 2.3 2 1 0 2 2 2 1 SET domain zf-HC5HC2H_2 PF13832.6 RJW64402.1 - 5.8e-10 39.3 6.3 1.9e-09 37.6 6.3 1.9 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RJW64402.1 - 1.2e-08 35.1 6.8 3.9e-08 33.4 6.8 2.0 1 0 0 1 1 1 1 PHD-like zinc-binding domain C1_2 PF03107.16 RJW64402.1 - 4.7 7.6 9.7 1.4 9.3 2.2 3.3 3 0 0 3 3 3 0 C1 domain Ion_trans PF00520.31 RJW64403.1 - 1.4e-35 122.8 48.1 3.9e-32 111.4 24.6 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 RJW64403.1 - 0.048 12.3 32.4 0.073 11.7 6.0 4.7 4 1 1 5 5 5 0 Polycystin cation channel GNT-I PF03071.15 RJW64404.1 - 9.4e-111 370.6 0.0 1.2e-110 370.3 0.0 1.0 1 0 0 1 1 1 1 GNT-I family TFB6 PF17110.5 RJW64406.1 - 0.021 14.6 1.3 0.022 14.5 1.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sigma70_ner PF04546.13 RJW64406.1 - 0.028 14.3 7.5 0.027 14.4 7.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.11 RJW64406.1 - 0.04 13.5 7.9 0.036 13.7 7.9 1.0 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.11 RJW64406.1 - 0.13 12.2 9.3 0.16 11.9 9.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 RJW64406.1 - 0.17 11.1 24.4 0.21 10.9 24.4 1.1 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 RJW64406.1 - 0.22 10.9 11.2 0.21 11.0 11.2 1.0 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 RJW64406.1 - 0.55 9.3 29.1 0.63 9.1 29.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 RJW64406.1 - 0.7 10.1 17.6 0.66 10.2 17.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.11 RJW64406.1 - 1 7.8 11.9 1.1 7.7 11.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 RJW64406.1 - 1.1 7.5 13.8 1.2 7.3 13.8 1.0 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 RJW64406.1 - 1.8 9.0 30.1 3.4 8.1 30.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 RJW64406.1 - 3.6 5.7 15.3 4.1 5.5 15.3 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 RJW64406.1 - 4.3 6.7 11.6 4.8 6.5 11.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 RJW64406.1 - 5.3 6.7 13.2 24 4.6 13.2 1.8 1 1 0 1 1 1 0 FAM176 family Peptidase_M60 PF13402.6 RJW64407.1 - 1.1e-18 67.8 0.1 2.6e-18 66.5 0.1 1.6 1 1 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 RJW64407.1 - 7.5e-07 29.0 0.1 4.6e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of M60-like peptidases BRCT_2 PF16589.5 RJW64407.1 - 0.075 13.4 0.2 1.5 9.3 0.0 2.8 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain Helicase_C_2 PF13307.6 RJW64408.1 - 7.8e-46 156.4 0.0 1.4e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 RJW64408.1 - 0.00072 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Helical and beta-bridge domain SNARE_assoc PF09335.11 RJW64409.1 - 2.4e-12 47.4 2.8 6e-12 46.1 2.8 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein zf-CSL PF05207.13 RJW64410.1 - 2.7e-23 81.5 1.3 3.2e-23 81.2 1.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Prok-RING_1 PF14446.6 RJW64410.1 - 0.044 13.7 0.4 0.076 13.0 0.4 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 RJW64410.1 - 0.25 11.5 3.5 0.2 11.8 1.6 1.8 1 1 1 2 2 2 0 Zinc ribbon domain Cadherin PF00028.17 RJW64411.1 - 5.9e-68 225.4 1.7 8.5e-13 48.6 0.0 9.3 8 1 0 8 8 8 8 Cadherin domain Cadherin_3 PF16184.5 RJW64411.1 - 1.4e-06 28.3 6.5 0.26 11.3 0.0 6.6 7 0 0 7 7 7 2 Cadherin-like Cadherin_2 PF08266.12 RJW64411.1 - 2.8e-06 27.1 0.1 1 9.3 0.0 4.4 5 0 0 5 5 5 2 Cadherin-like RET_CLD1 PF17756.1 RJW64411.1 - 0.0014 18.9 0.0 0.2 11.9 0.0 3.5 4 0 0 4 4 4 1 RET Cadherin like domain 1 Cadherin_4 PF17803.1 RJW64411.1 - 0.029 15.0 13.5 0.31 11.7 0.1 5.2 5 1 0 5 5 5 0 Bacterial cadherin-like domain SusE PF14292.6 RJW64411.1 - 0.089 13.0 1.3 12 6.1 0.0 3.7 3 0 0 3 3 3 0 SusE outer membrane protein Curto_V2 PF07325.11 RJW64412.1 - 0.18 11.7 2.0 3.1 7.7 0.3 2.4 2 0 0 2 2 2 0 Curtovirus V2 protein Caskin-Pro-rich PF16907.5 RJW64412.1 - 0.67 10.5 4.0 28 5.3 0.2 3.4 3 0 0 3 3 3 0 Proline rich region of Caskin proteins HSL_N PF06350.12 RJW64413.1 - 3e-39 134.8 0.0 1e-38 133.1 0.0 1.7 2 0 0 2 2 2 1 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.13 RJW64413.1 - 1.4e-37 129.6 0.0 7.2e-28 97.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RJW64413.1 - 7e-08 31.7 0.0 1.4e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase Sod_Cu PF00080.20 RJW64416.1 - 3.1e-27 95.5 0.1 4.8e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Peptidase_S10 PF00450.22 RJW64417.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase DNA_pol_A PF00476.20 RJW64419.1 - 6.3e-77 259.2 0.0 4.5e-74 249.8 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family A DEAD PF00270.29 RJW64419.1 - 4.3e-16 59.2 0.0 1.1e-13 51.3 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW64419.1 - 4.3e-11 43.1 0.0 6.5e-10 39.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW64419.1 - 0.0086 16.1 0.0 0.041 13.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 RJW64419.1 - 0.061 13.9 0.0 0.37 11.4 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain Zn_Tnp_IS91 PF14319.6 RJW64419.1 - 0.72 9.9 3.8 1.8 8.6 3.8 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain eIF-3c_N PF05470.12 RJW64420.1 - 2.5e-168 561.1 27.8 9.1e-167 556.0 27.8 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RVT_1 PF00078.27 RJW64420.1 - 4.6e-18 65.5 0.0 1.2e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PCI PF01399.27 RJW64420.1 - 5.8e-10 39.6 0.0 4.5e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 PCI domain RYDR_ITPR PF01365.21 RJW64420.1 - 0.18 11.2 1.4 0.41 10.0 1.4 1.5 1 0 0 1 1 1 0 RIH domain SR-25 PF10500.9 RJW64420.1 - 1.1 8.8 21.0 0.19 11.3 11.8 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PA26 PF04636.13 RJW64420.1 - 1.9 7.3 15.2 0.04 12.8 6.8 2.0 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) Per1 PF04080.13 RJW64422.1 - 9e-78 261.6 15.7 1.1e-77 261.2 15.7 1.1 1 0 0 1 1 1 1 Per1-like family Aegerolysin PF06355.13 RJW64423.1 - 0.068 13.3 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Aegerolysin NHL PF01436.21 RJW64424.1 - 5.1e-09 35.7 8.6 0.011 15.7 0.1 5.3 6 0 0 6 6 6 3 NHL repeat IML1 PF12257.8 RJW64425.1 - 2.5e-85 286.1 0.0 3.8e-85 285.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 Ribonuc_L-PSP PF01042.21 RJW64426.1 - 7.8e-46 155.0 0.9 8.8e-46 154.9 0.9 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP M60-like_N PF17291.2 RJW64427.1 - 5.5e-06 26.2 0.0 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 RJW64427.1 - 0.012 15.2 0.3 0.069 12.7 0.3 2.1 1 1 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like WIYLD PF10440.9 RJW64427.1 - 0.13 12.0 0.1 13 5.7 0.0 2.9 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Sod_Cu PF00080.20 RJW64428.1 - 1.2e-31 109.8 0.1 1.6e-31 109.4 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) WD40 PF00400.32 RJW64430.1 - 1.4e-15 57.4 10.8 0.0031 18.3 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat FYVE PF01363.21 RJW64430.1 - 6.1e-14 51.9 5.9 1.2e-13 51.0 5.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger ANAPC4_WD40 PF12894.7 RJW64430.1 - 0.0004 20.6 0.3 7.2 7.0 0.2 3.4 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RJW64430.1 - 0.013 14.3 0.3 0.26 10.0 0.0 2.5 2 1 0 3 3 3 0 Nup133 N terminal like DUF2688 PF10892.8 RJW64430.1 - 0.79 9.2 3.9 0.77 9.3 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) FYVE_2 PF02318.16 RJW64430.1 - 1.7 8.9 5.3 4.9 7.4 5.3 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger Peptidase_M14 PF00246.24 RJW64432.1 - 1.3e-12 48.1 0.0 2.7e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase RVT_1 PF00078.27 RJW64433.1 - 7e-17 61.7 0.1 3.1e-14 53.0 0.1 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sod_Cu PF00080.20 RJW64434.1 - 2.5e-36 125.0 0.5 3.1e-36 124.7 0.5 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) T-box_assoc PF16176.5 RJW64438.1 - 0.00099 19.3 4.4 0.19 11.8 0.6 2.9 1 1 3 4 4 4 4 T-box transcription factor-associated Metallothio_Euk PF12749.7 RJW64438.1 - 0.76 10.0 11.4 7.5 6.8 0.4 3.1 1 1 2 3 3 3 0 Eukaryotic metallothionein CEP76-C2 PF15627.6 RJW64439.1 - 1.2e-42 145.2 0.0 2e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain DUF2002 PF09400.10 RJW64439.1 - 0.022 14.8 0.0 0.88 9.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2002) Gemini_C4 PF01492.17 RJW64439.1 - 0.036 14.0 0.2 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 Geminivirus C4 protein Transglut_core PF01841.19 RJW64439.1 - 0.05 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily Serpin PF00079.20 RJW64441.1 - 2.7e-54 184.9 0.2 7e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) STT3 PF02516.14 RJW64442.1 - 1.3e-114 383.9 36.2 1.2e-113 380.7 36.2 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 RJW64442.1 - 0.001 19.3 14.3 0.001 19.3 14.3 3.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPP_enzyme_C PF02775.21 RJW64443.1 - 1.2e-19 70.6 0.0 2.9e-19 69.4 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DC_STAMP PF07782.13 RJW64444.1 - 1.8e-37 129.0 0.1 5.1e-37 127.5 0.1 1.8 1 0 0 1 1 1 1 DC-STAMP-like protein DUF555 PF04475.12 RJW64444.1 - 0.097 13.0 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF555) Tnp_zf-ribbon_2 PF13842.6 RJW64444.1 - 0.8 10.6 3.1 3 8.7 3.1 2.0 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-Sec23_Sec24 PF04810.15 RJW64444.1 - 1.8 8.6 8.5 7.1 6.8 6.0 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Methyltransf_15 PF09445.10 RJW64446.1 - 4.6e-34 117.4 0.0 7e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 RJW64446.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW64446.1 - 0.0014 19.3 0.0 0.003 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RJW64446.1 - 0.0027 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 RJW64446.1 - 0.0088 15.7 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) UPF0020 PF01170.18 RJW64446.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.14 RJW64446.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain SAM_MT PF04445.13 RJW64446.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Met_10 PF02475.16 RJW64446.1 - 0.095 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein RrnaAD PF00398.20 RJW64446.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 RJW64446.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB E1_DerP2_DerF2 PF02221.15 RJW64449.1 - 2.9e-07 31.0 0.0 3.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ML domain KCNQ_channel PF03520.14 RJW64452.1 - 7.7e-35 120.5 5.3 3.5e-34 118.3 5.3 1.9 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 RJW64452.1 - 2e-17 63.3 3.6 2.9e-17 62.7 3.6 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW64452.1 - 3.2e-14 52.6 4.5 6e-14 51.8 4.5 1.4 1 0 0 1 1 1 1 Ion channel TMEM72 PF16054.5 RJW64452.1 - 0.13 12.0 0.3 0.7 9.6 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein family 72 SecE PF00584.20 RJW64452.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex IQ PF00612.27 RJW64452.1 - 0.52 10.3 6.7 0.37 10.7 0.1 3.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif PRIMA1 PF16101.5 RJW64453.1 - 0.13 12.3 2.3 0.7 9.9 0.7 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SecD_SecF PF02355.16 RJW64454.1 - 0.007 15.8 6.9 2.4 7.5 6.9 2.4 1 1 0 1 1 1 1 Protein export membrane protein DUF445 PF04286.12 RJW64454.1 - 0.012 15.4 3.6 0.014 15.2 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PdaC PF13739.6 RJW64454.1 - 0.083 13.9 18.1 6e+02 1.5 18.1 3.0 1 1 0 1 1 1 0 Deacetylase PdaC YpjP PF14005.6 RJW64454.1 - 0.089 12.8 3.0 0.15 12.1 3.0 1.5 1 0 0 1 1 1 0 YpjP-like protein EcsC PF12787.7 RJW64454.1 - 0.12 12.0 1.5 0.31 10.7 1.5 1.6 1 1 0 1 1 1 0 EcsC protein family CEL_III_C PF18054.1 RJW64454.1 - 0.2 11.7 6.0 0.29 11.2 6.0 1.3 1 0 0 1 1 1 0 CEL-III C-terminal Glycoprot_B_PH2 PF17417.2 RJW64454.1 - 0.31 11.4 6.3 2.5 8.5 2.0 2.3 1 1 1 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain Tn7_Tnp_TnsA_C PF08721.11 RJW64454.1 - 0.43 11.2 7.4 0.23 12.1 1.6 2.2 1 1 1 2 2 2 0 TnsA endonuclease C terminal ABC2_membrane_3 PF12698.7 RJW64454.1 - 0.7 8.9 10.3 0.87 8.6 10.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein ING PF12998.7 RJW64454.1 - 0.74 10.4 7.7 2.8 8.6 7.7 1.8 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Coat_F PF07875.12 RJW64454.1 - 4.1 7.7 11.0 1.2e+03 -0.2 11.0 2.3 1 1 0 1 1 1 0 Coat F domain IPPT PF01715.17 RJW64455.1 - 5.9e-46 157.1 0.0 1e-45 156.3 0.0 1.4 1 0 0 1 1 1 1 IPP transferase LETM1 PF07766.13 RJW64455.1 - 1e-22 80.8 0.8 1.9e-22 79.9 0.8 1.3 1 0 0 1 1 1 1 LETM1-like protein IPT PF01745.16 RJW64455.1 - 0.00094 18.6 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 RJW64455.1 - 0.0013 18.9 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 RJW64455.1 - 0.0074 16.0 0.2 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase AAA_18 PF13238.6 RJW64455.1 - 0.0097 16.5 1.1 0.59 10.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 RJW64455.1 - 0.019 14.7 0.2 0.033 13.9 0.2 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 RJW64455.1 - 0.035 13.7 0.0 0.099 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RJW64455.1 - 0.094 13.2 0.2 0.19 12.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 RJW64455.1 - 0.13 12.3 0.3 0.31 11.1 0.3 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 RJW64455.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 RJW64455.1 - 0.17 11.6 0.1 0.42 10.3 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 RJW64455.1 - 0.29 11.4 1.4 0.77 10.0 0.3 2.1 2 0 0 2 2 2 0 AAA domain Peptidase_C37 PF05416.12 RJW64458.1 - 0.19 10.2 4.7 0.24 9.9 4.7 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase PID PF00640.23 RJW64461.1 - 1.6e-23 83.3 0.1 2.2e-23 82.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 RJW64461.1 - 1.1e-16 60.7 0.0 1.9e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 SH2 domain PID_2 PF14719.6 RJW64461.1 - 0.0078 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PARP_reg PF02877.14 RJW64463.1 - 4.2e-28 98.1 0.7 6.4e-28 97.5 0.7 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PARP PF00644.20 RJW64463.1 - 5.8e-16 58.7 0.0 9.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Tetraspanin PF00335.20 RJW64464.1 - 4.1e-28 98.6 3.1 4.9e-28 98.4 3.1 1.0 1 0 0 1 1 1 1 Tetraspanin family PsbK PF02533.15 RJW64464.1 - 0.053 13.7 0.8 0.13 12.4 0.8 1.7 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component Neurensin PF14927.6 RJW64464.1 - 3.6 7.3 12.0 0.14 11.9 5.3 1.9 1 1 1 2 2 2 0 Neurensin 7tm_3 PF00003.22 RJW64465.1 - 4e-52 177.3 17.8 4e-52 177.3 17.8 1.7 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Alpha_E2_glycop PF00943.19 RJW64469.1 - 1.4 7.6 5.0 2.5 6.7 5.0 1.4 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Iso_dh PF00180.20 RJW64470.1 - 1.1e-61 208.9 0.0 1.4e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase C1_1 PF00130.22 RJW64473.1 - 2.3e-27 94.6 49.6 2.9e-12 46.3 9.0 3.3 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) RA PF00788.23 RJW64473.1 - 2.2e-13 50.7 0.3 2.4e-05 24.9 0.0 2.7 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C1_2 PF03107.16 RJW64473.1 - 0.0055 17.0 28.0 0.021 15.1 4.5 3.8 3 0 0 3 3 3 2 C1 domain TUG-UBL1 PF11470.8 RJW64473.1 - 0.048 13.9 0.3 6.1 7.1 0.0 2.7 3 0 0 3 3 3 0 TUG ubiquitin-like domain PHD PF00628.29 RJW64473.1 - 5 7.1 37.6 0.48 10.3 7.8 3.6 3 0 0 3 3 3 0 PHD-finger DHHC PF01529.20 RJW64474.1 - 2.7e-27 95.5 11.0 2.7e-27 95.5 11.0 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase MDD_C PF18376.1 RJW64474.1 - 0.028 14.2 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain Carn_acyltransf PF00755.20 RJW64475.1 - 1.7e-157 525.6 0.0 2e-157 525.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase GRIP PF01465.20 RJW64477.1 - 4.4e-08 32.9 0.2 1.5e-07 31.2 0.2 2.0 1 0 0 1 1 1 1 GRIP domain PspA_IM30 PF04012.12 RJW64477.1 - 0.0022 17.6 0.2 0.0022 17.6 0.2 13.9 6 6 4 11 11 11 2 PspA/IM30 family Baculo_PEP_C PF04513.12 RJW64477.1 - 0.0053 16.8 4.8 0.0053 16.8 4.8 13.7 6 3 4 13 13 13 6 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 RJW64477.1 - 0.012 15.0 0.2 0.012 15.0 0.2 15.6 9 7 5 15 15 15 0 Growth-arrest specific micro-tubule binding MRI PF15325.6 RJW64478.1 - 0.65 11.1 5.0 0.24 12.5 1.2 2.2 2 1 0 2 2 2 0 Modulator of retrovirus infection E1_DerP2_DerF2 PF02221.15 RJW64479.1 - 4.2e-13 49.9 0.2 5e-13 49.6 0.2 1.1 1 0 0 1 1 1 1 ML domain TRAPPC9-Trs120 PF08626.11 RJW64480.1 - 0.0003 18.3 0.0 0.00048 17.6 0.0 1.3 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 RJW64480.1 - 0.017 15.4 0.1 0.05 13.9 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 RJW64480.1 - 1 9.7 2.4 0.97 9.7 0.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Exostosin PF03016.15 RJW64481.1 - 1.1e-52 179.1 0.1 6.8e-52 176.5 0.0 2.2 2 1 0 2 2 2 1 Exostosin family Glyco_transf_64 PF09258.10 RJW64481.1 - 2.1e-39 135.3 0.0 3.6e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain CAMSAP_CKK PF08683.11 RJW64484.1 - 2.1e-43 147.3 0.0 3.7e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated RRM_1 PF00076.22 RJW64485.1 - 1.7e-18 66.2 0.0 2.5e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW64485.1 - 0.00019 21.5 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Pkinase PF00069.25 RJW64489.1 - 1.2e-46 159.3 0.0 3.4e-46 157.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64489.1 - 8.6e-21 74.4 0.1 3.3e-20 72.5 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 RJW64489.1 - 0.048 13.2 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DNA_pol_phi PF04931.13 RJW64489.1 - 3.5 5.6 32.5 4.6 5.2 32.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RJW64489.1 - 3.9 5.6 14.7 5.5 5.2 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 RJW64489.1 - 4.1 5.7 12.5 5.8 5.2 12.5 1.1 1 0 0 1 1 1 0 Mpp10 protein WGR PF05406.15 RJW64491.1 - 2.9e-06 27.2 0.1 3.9e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 WGR domain HMG_box PF00505.19 RJW64492.1 - 9.8e-26 90.0 0.9 1.8e-25 89.1 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW64492.1 - 1.3e-08 35.3 0.7 2.4e-08 34.4 0.7 1.4 1 0 0 1 1 1 1 HMG-box domain S4 PF01479.25 RJW64493.1 - 3.5e-09 36.2 0.2 1.4e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 RJW64493.1 - 1.1e-07 32.6 0.5 3.7e-07 31.0 0.5 1.9 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain RVT_1 PF00078.27 RJW64493.1 - 0.0021 17.6 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MSG PF02349.15 RJW64495.1 - 0.23 11.6 2.7 0.97 9.7 2.7 2.0 1 1 0 1 1 1 0 Major surface glycoprotein I-set PF07679.16 RJW64497.1 - 2.7e-65 216.5 0.0 5.2e-13 48.9 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW64497.1 - 1.2e-43 147.6 0.0 5.3e-08 33.3 0.0 5.8 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 RJW64497.1 - 1.1e-29 102.6 0.0 1.2e-05 25.6 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 RJW64497.1 - 6.8e-23 80.6 0.1 6e-06 26.3 0.0 5.9 5 1 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 RJW64497.1 - 2.3e-19 69.6 0.1 0.00058 20.0 0.0 7.3 5 3 0 5 5 5 3 Immunoglobulin V-set domain BiPBP_C PF06832.12 RJW64497.1 - 2.2e-07 30.8 0.0 2.2 8.4 0.0 5.2 5 0 0 5 5 5 3 Penicillin-Binding Protein C-terminus Family C1-set PF07654.15 RJW64497.1 - 1.8e-06 28.2 0.0 3.2 8.2 0.0 4.9 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 RJW64497.1 - 7e-06 25.5 0.4 4.8 6.8 0.0 4.4 4 0 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 RJW64497.1 - 2.6e-05 24.2 0.0 0.56 10.3 0.0 4.2 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 RJW64497.1 - 6.8e-05 23.0 0.0 4.9 7.5 0.0 4.6 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 RJW64497.1 - 0.00062 19.9 0.0 5.8 7.2 0.0 4.0 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 Alpha-amylase_C PF02806.18 RJW64498.1 - 2e-27 95.5 0.0 5.4e-27 94.1 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 RJW64498.1 - 4.8e-13 49.3 0.0 1.2e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 RJW64498.1 - 7.2e-13 48.8 0.0 2.2e-10 40.6 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Lig_chan PF00060.26 RJW64499.1 - 2e-21 76.4 0.7 2.8e-21 75.9 0.7 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RJW64499.1 - 4.2e-05 23.1 0.0 0.00013 21.5 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 RJW64499.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site ATP-synt_8 PF00895.20 RJW64499.1 - 0.9 10.0 8.2 0.2 12.2 0.5 3.0 3 0 0 3 3 3 0 ATP synthase protein 8 Memo PF01875.17 RJW64501.1 - 3.1e-67 226.6 0.0 4e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Kunitz_BPTI PF00014.23 RJW64503.1 - 4.1e-123 401.6 137.3 1.9e-19 69.7 4.1 14.8 14 0 0 14 14 14 12 Kunitz/Bovine pancreatic trypsin inhibitor domain SNF PF00209.18 RJW64504.1 - 8.1e-33 113.9 36.6 2.1e-16 59.7 17.6 2.6 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family LEAP-2 PF07359.11 RJW64504.1 - 0.071 13.0 0.2 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) RRM_1 PF00076.22 RJW64505.1 - 2.2e-32 110.7 0.0 9.9e-18 63.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RJW64505.1 - 7.6e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 RJW64505.1 - 0.00039 20.4 0.0 0.043 13.9 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 RJW64505.1 - 0.0012 19.0 0.0 0.0034 17.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 RJW64505.1 - 0.0085 16.1 0.0 0.067 13.2 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Fis1_TPR_C PF14853.6 RJW64506.1 - 2.7e-22 78.6 0.1 4.6e-22 77.8 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 RJW64506.1 - 9.2e-09 34.8 0.0 1.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_1 PF00515.28 RJW64506.1 - 9.5e-05 22.1 0.2 0.00019 21.1 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW64506.1 - 0.0004 20.6 0.2 0.0013 18.9 0.1 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RJW64506.1 - 0.0012 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW64506.1 - 0.0086 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW64506.1 - 0.011 16.4 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 RJW64506.1 - 0.027 15.3 0.0 0.11 13.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW64506.1 - 0.036 14.7 0.0 0.09 13.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Coiled-coil_56 PF09813.9 RJW64506.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 LANC_like PF05147.13 RJW64506.1 - 0.12 11.0 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein TPR_9 PF13371.6 RJW64506.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 RJW64506.1 - 0.14 12.7 0.0 0.26 11.8 0.0 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat LRR_4 PF12799.7 RJW64507.1 - 1.5e-07 31.6 2.4 0.00023 21.5 0.1 3.1 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW64507.1 - 5.8e-07 29.2 2.0 1.3e-06 28.1 1.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 RJW64507.1 - 0.00033 20.8 4.1 0.24 12.1 0.3 4.8 3 0 0 3 3 3 1 Leucine Rich Repeat Apolipoprotein PF01442.18 RJW64507.1 - 0.0009 19.2 0.2 0.0015 18.5 0.2 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Ig_3 PF13927.6 RJW64507.1 - 0.013 16.1 0.3 0.036 14.7 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 RJW64507.1 - 0.08 13.0 0.0 0.29 11.2 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin I-set domain LRR_6 PF13516.6 RJW64507.1 - 0.31 11.2 2.1 9.2 6.6 0.6 2.9 2 0 0 2 2 2 0 Leucine Rich repeat zf-RING_9 PF13901.6 RJW64508.1 - 1.4e-37 129.7 0.4 2.5e-37 128.9 0.4 1.3 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon LIM PF00412.22 RJW64508.1 - 0.54 10.5 6.2 0.13 12.5 1.6 2.3 2 0 0 2 2 2 0 LIM domain WD40 PF00400.32 RJW64509.1 - 3.2e-08 34.1 0.2 0.88 10.5 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Fe-S_biosyn PF01521.20 RJW64509.1 - 0.0058 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis HA2 PF04408.23 RJW64510.1 - 1.4e-14 54.2 0.0 4.1e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RJW64510.1 - 6.7e-14 52.2 0.2 2.6e-13 50.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RJW64510.1 - 5.8e-10 39.2 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RJW64510.1 - 1.9e-05 24.9 0.0 8.5e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 RJW64510.1 - 8.3e-05 22.9 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 RJW64510.1 - 0.00081 19.7 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 RJW64510.1 - 0.011 15.2 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 RJW64510.1 - 0.016 14.4 0.0 0.044 13.0 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain ALF PF03752.13 RJW64510.1 - 0.02 14.9 0.2 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Short repeats of unknown function T2SSE PF00437.20 RJW64510.1 - 0.021 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 RJW64510.1 - 0.022 15.3 0.1 0.065 13.8 0.1 1.8 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 RJW64510.1 - 0.052 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 RJW64510.1 - 0.081 12.9 0.1 8.7 6.3 0.1 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 RJW64510.1 - 0.089 13.2 0.1 0.4 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 RJW64510.1 - 0.16 12.0 0.1 2 8.5 0.1 2.6 1 1 0 1 1 1 0 AAA domain Memo PF01875.17 RJW64511.1 - 1.2e-80 270.6 0.0 1.3e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein EMP70 PF02990.16 RJW64512.1 - 8.7e-35 120.4 0.0 1.2e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 CRAL_TRIO PF00650.20 RJW64516.1 - 2.4e-14 53.4 0.0 3.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Y_phosphatase PF00102.27 RJW64516.1 - 6.7e-11 42.2 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO_2 PF13716.6 RJW64516.1 - 0.0054 16.9 0.1 0.011 15.9 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RVT_1 PF00078.27 RJW64516.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Amb_V_allergen PF03913.13 RJW64516.1 - 0.16 11.9 0.2 0.39 10.7 0.2 1.5 1 0 0 1 1 1 0 Amb V Allergen Hydrolase_4 PF12146.8 RJW64517.1 - 1.3e-10 40.9 0.3 4.5e-06 26.1 0.1 2.4 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RJW64517.1 - 5.6e-06 27.1 1.0 0.00029 21.5 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RJW64517.1 - 1.9e-05 24.4 0.0 0.011 15.4 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 RJW64517.1 - 0.0012 17.8 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 RJW64517.1 - 0.027 13.9 0.0 0.94 8.9 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 RJW64517.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) HEAT PF02985.22 RJW64518.1 - 1.8e-07 30.8 3.8 0.99 9.8 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat Pkinase PF00069.25 RJW64518.1 - 9.7e-06 25.1 0.0 0.06 12.7 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 RJW64518.1 - 0.0003 21.5 0.2 0.0015 19.3 0.0 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat Adap_comp_sub PF00928.21 RJW64519.1 - 5.6e-64 216.1 0.0 7e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RJW64519.1 - 0.00048 20.1 0.9 0.0018 18.2 0.9 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.22 RJW64520.1 - 7e-21 73.8 0.0 3.5e-11 42.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 RJW64520.1 - 7.6e-11 42.1 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 SPOC domain RRM_3 PF08777.11 RJW64520.1 - 6.3e-07 29.4 0.0 0.027 14.5 0.0 3.4 3 0 0 3 3 3 3 RNA binding motif RRM_7 PF16367.5 RJW64520.1 - 1.2e-05 25.4 0.0 0.003 17.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RJW64520.1 - 0.013 15.5 0.0 0.096 12.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Y_phosphatase PF00102.27 RJW64521.1 - 6.3e-31 107.7 0.1 9.5e-31 107.2 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RJW64521.1 - 0.0074 16.1 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RJW64521.1 - 0.016 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RJW64521.1 - 0.025 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3602 PF12223.8 RJW64521.1 - 0.073 13.7 0.2 0.24 12.0 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) MRP-S24 PF14955.6 RJW64522.1 - 9e-58 194.1 0.3 1.4e-57 193.4 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 PhoLip_ATPase_C PF16212.5 RJW64524.1 - 3.7e-82 275.8 22.5 3.7e-82 275.8 22.5 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 RJW64524.1 - 2.5e-12 46.7 0.0 2.5e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RJW64524.1 - 1.1e-11 45.4 0.4 3.1e-05 24.4 0.4 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RJW64524.1 - 0.0031 17.3 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SIR2 PF02146.17 RJW64526.1 - 1.7e-57 194.2 0.0 2.5e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-RING_7 PF02591.15 RJW64526.1 - 0.00013 22.0 1.1 0.00036 20.6 1.1 1.8 1 0 0 1 1 1 1 C4-type zinc ribbon domain zf-DNL PF05180.12 RJW64526.1 - 0.044 13.7 2.4 0.092 12.7 2.4 1.5 1 0 0 1 1 1 0 DNL zinc finger DZR PF12773.7 RJW64526.1 - 1.6 8.9 5.8 0.34 11.0 0.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon EMC3_TMCO1 PF01956.16 RJW64527.1 - 0.041 13.6 5.8 1.2 8.9 5.9 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like RVT_1 PF00078.27 RJW64528.1 - 1.5e-45 155.4 0.0 3.1e-42 144.6 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) R3H PF01424.22 RJW64528.1 - 1.1e-11 44.6 0.0 2.8e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 RJW64528.1 - 0.00029 20.8 40.3 0.00044 20.2 17.1 13.0 13 1 1 14 14 14 7 NF-X1 type zinc finger PAS_9 PF13426.7 RJW64529.1 - 6.4e-18 64.9 0.0 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 RJW64529.1 - 3.7e-10 39.8 0.0 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 RJW64529.1 - 2.1e-07 31.2 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 RJW64529.1 - 7.9e-07 29.3 0.0 1.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF4542 PF15075.6 RJW64530.1 - 1.9e-19 70.4 0.3 1.9e-19 70.4 0.3 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4542) DDHD PF02862.17 RJW64530.1 - 2 8.5 5.9 2.4 8.2 5.9 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 RJW64530.1 - 4.5 5.9 9.1 4.5 5.9 9.1 1.1 1 0 0 1 1 1 0 Presenilin Trypsin PF00089.26 RJW64531.1 - 4.3e-12 46.3 0.1 5.4e-12 46.0 0.1 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 RJW64531.1 - 0.001 19.4 0.1 0.0013 19.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 RJW64531.1 - 0.011 16.7 0.0 0.016 16.1 0.0 1.3 1 0 0 1 1 1 0 Trypsin-like peptidase domain DUF316 PF03761.15 RJW64531.1 - 0.056 13.0 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 PHD PF00628.29 RJW64532.1 - 6.4e-20 70.8 25.5 2.2e-12 46.7 6.3 3.4 2 1 2 4 4 4 2 PHD-finger zf-C2H2_4 PF13894.6 RJW64532.1 - 0.014 16.2 0.5 0.014 16.2 0.5 5.4 6 0 0 6 6 6 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RJW64532.1 - 0.022 14.4 0.0 0.022 14.4 0.0 2.1 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 RJW64532.1 - 0.023 15.1 0.4 0.023 15.1 0.4 3.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Lar_restr_allev PF14354.6 RJW64532.1 - 1.9 8.9 18.8 4.1e+02 1.5 0.0 3.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar C1_1 PF00130.22 RJW64532.1 - 9.5 6.2 26.9 0.4 10.6 3.5 3.9 3 1 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DAG1 PF05454.11 RJW64533.1 - 0.093 12.1 2.5 0.19 11.0 2.5 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) SKG6 PF08693.10 RJW64533.1 - 0.13 11.7 1.9 0.26 10.7 1.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AA_permease_2 PF13520.6 RJW64534.1 - 2.3e-26 92.6 25.5 2.3e-26 92.6 25.5 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 RJW64534.1 - 7.9e-16 57.7 23.0 7.9e-16 57.7 23.0 2.1 2 0 0 2 2 2 2 Amino acid permease Ank_2 PF12796.7 RJW64535.1 - 9.2e-79 260.1 20.6 3.2e-15 56.5 0.1 7.6 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW64535.1 - 1.4e-67 223.2 24.2 1.6e-10 41.3 0.1 9.7 4 3 6 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW64535.1 - 1e-56 182.2 17.9 0.00012 22.2 0.1 12.9 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 RJW64535.1 - 1.2e-50 168.9 16.7 3.6e-08 33.5 0.1 12.1 5 3 8 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 RJW64535.1 - 2.1e-47 157.6 27.2 0.00024 21.4 0.0 12.1 12 1 1 13 13 13 10 Ankyrin repeat Sacchrp_dh_NADP PF03435.18 RJW64535.1 - 0.092 13.0 0.8 7.2 6.9 0.1 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AA_permease_2 PF13520.6 RJW64536.1 - 3.2e-67 227.2 68.5 2.2e-38 132.2 27.9 3.9 4 0 0 4 4 4 2 Amino acid permease AA_permease PF00324.21 RJW64536.1 - 4.2e-48 164.1 72.1 9.3e-29 100.3 29.7 3.6 4 0 0 4 4 4 2 Amino acid permease AA_permease_C PF13906.6 RJW64536.1 - 8.2e-14 51.4 3.6 8.2e-14 51.4 3.6 5.0 5 0 0 5 5 5 1 C-terminus of AA_permease TTL PF03133.15 RJW64537.1 - 3.6e-20 72.3 0.0 8e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Rb_C PF08934.10 RJW64537.1 - 0.041 13.7 0.2 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 Rb C-terminal domain Glycogen_syn PF05693.13 RJW64539.1 - 0 1067.1 0.0 0 1066.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 RJW64539.1 - 2.7e-07 30.3 0.0 0.00021 20.9 0.0 2.6 2 1 1 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 RJW64539.1 - 2e-06 27.7 0.0 5.8e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 RJW64539.1 - 8e-06 26.3 0.0 0.0051 17.2 0.0 2.8 2 1 1 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RJW64539.1 - 0.0059 16.6 0.2 0.016 15.2 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 ACT_3 PF10000.9 RJW64539.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ACT domain Pkinase PF00069.25 RJW64540.1 - 9.7e-64 215.3 0.0 1.2e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64540.1 - 5.5e-37 127.5 0.0 9.1e-35 120.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW64540.1 - 0.00041 19.4 0.0 0.00087 18.3 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RJW64540.1 - 0.0017 17.2 0.1 0.0043 15.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RJW64540.1 - 0.034 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RJW64540.1 - 0.14 12.1 0.1 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RJW64540.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HMG_box PF00505.19 RJW64541.1 - 1.6e-23 82.9 2.8 4.2e-23 81.5 2.8 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW64541.1 - 2.8e-07 31.0 0.8 6.5e-07 29.9 0.8 1.6 1 0 0 1 1 1 1 HMG-box domain PAN_3 PF08277.12 RJW64542.1 - 0.14 12.0 10.6 1.4 8.8 1.8 3.1 2 1 1 3 3 3 0 PAN-like domain zf-Tim10_DDP PF02953.15 RJW64542.1 - 2 8.1 11.7 1 9.1 5.5 2.3 1 1 1 2 2 2 0 Tim10/DDP family zinc finger TIL PF01826.17 RJW64542.1 - 5.1 7.4 14.0 1.9e+03 -0.8 14.0 2.4 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Tctex-1 PF03645.13 RJW64544.1 - 0.00044 20.4 0.0 0.00091 19.4 0.0 1.6 1 1 0 1 1 1 1 Tctex-1 family PAN_1 PF00024.26 RJW64545.1 - 0.0022 17.9 0.3 0.0022 17.9 0.3 1.7 2 0 0 2 2 2 1 PAN domain Ig_3 PF13927.6 RJW64546.1 - 3.9e-70 232.5 2.4 2.1e-15 57.1 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 RJW64546.1 - 1.1e-64 214.5 0.0 4.9e-13 49.0 0.0 6.7 7 0 0 7 7 7 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW64546.1 - 3e-47 158.9 0.1 2.9e-09 37.1 0.0 6.1 5 1 1 6 6 6 5 Immunoglobulin domain ig PF00047.25 RJW64546.1 - 7.9e-37 125.3 0.0 1.1e-07 31.9 0.1 6.6 5 2 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 RJW64546.1 - 3.4e-25 88.3 3.0 5.7e-06 26.5 0.1 8.8 6 4 0 6 6 6 5 Immunoglobulin V-set domain fn3 PF00041.21 RJW64546.1 - 8.6e-17 61.3 0.7 1.9e-10 41.0 0.1 3.4 2 1 0 2 2 2 2 Fibronectin type III domain Ig_6 PF18452.1 RJW64546.1 - 1.9e-14 52.9 0.0 0.073 12.7 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain C2-set_2 PF08205.12 RJW64546.1 - 2.4e-10 40.3 0.6 0.082 13.0 0.0 5.6 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 RJW64546.1 - 2.1e-08 34.4 0.0 0.019 15.3 0.0 4.8 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RJW64546.1 - 3e-08 33.8 0.0 2.1 8.7 0.0 5.8 6 0 0 6 6 6 3 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 RJW64546.1 - 3.1e-06 27.5 0.9 3.5 8.1 0.0 6.1 7 0 0 7 7 7 1 Immunoglobulin C1-set domain BiPBP_C PF06832.12 RJW64546.1 - 0.00024 21.1 0.1 3.7 7.7 0.0 4.5 5 0 0 5 5 5 1 Penicillin-Binding Protein C-terminus Family zf-RRN7 PF11781.8 RJW64546.1 - 0.0095 15.6 1.3 0.42 10.4 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF4200 PF13863.6 RJW64547.1 - 2.5e-14 53.7 8.9 2.5e-14 53.7 8.9 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Lebercilin PF15619.6 RJW64547.1 - 0.0012 18.5 4.9 0.0012 18.5 4.9 2.9 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease MCM_N PF14551.6 RJW64547.1 - 0.02 15.4 0.4 0.078 13.6 0.4 2.0 1 0 0 1 1 1 0 MCM N-terminal domain YabA PF06156.13 RJW64547.1 - 0.81 10.4 10.9 3 8.5 3.7 2.7 2 0 0 2 2 2 0 Initiation control protein YabA Vps51 PF08700.11 RJW64547.1 - 3.7 7.7 9.0 3.9 7.6 5.4 3.1 1 1 1 2 2 2 0 Vps51/Vps67 SDA1 PF05285.12 RJW64548.1 - 2.2e-79 267.4 29.9 2.2e-79 267.4 29.9 2.0 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 RJW64548.1 - 6.6e-13 48.8 0.0 2.1e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Cnd1 PF12717.7 RJW64548.1 - 0.00078 19.5 0.4 0.0039 17.3 0.3 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 RJW64548.1 - 0.035 13.7 1.0 0.059 12.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) Dppa2_A PF14049.6 RJW64548.1 - 0.22 11.7 0.1 0.22 11.7 0.1 3.5 5 0 0 5 5 5 0 Dppa2/4 conserved region in higher vertebrates RVT_1 PF00078.27 RJW64549.1 - 2.4e-05 24.0 0.1 3.7e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp PF00026.23 RJW64550.1 - 0.0014 18.1 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF3847 PF12958.7 RJW64551.1 - 3.9 7.6 5.9 1.7 8.8 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Glyco_transf_49 PF13896.6 RJW64552.1 - 1.2e-57 195.8 2.2 5.8e-46 157.4 0.6 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.20 RJW64552.1 - 2.1e-14 53.7 0.0 5.9e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 8 Amidohydro_3 PF07969.11 RJW64553.1 - 0.05 13.1 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family adh_short PF00106.25 RJW64555.1 - 7.5e-23 81.0 0.0 8.5e-21 74.3 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW64555.1 - 2.2e-11 43.8 0.0 5.9e-10 39.1 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW64555.1 - 4.5e-05 23.4 0.0 9.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 KR domain TPR_10 PF13374.6 RJW64557.1 - 3.2e-14 52.3 0.6 2.7e-06 27.1 0.3 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW64557.1 - 5.2e-13 49.1 0.0 1.1e-08 35.3 0.1 3.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW64557.1 - 9.5e-10 38.4 0.2 1.3e-08 34.6 0.1 2.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 RJW64557.1 - 2.5e-07 30.4 2.0 0.083 13.1 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW64557.1 - 4.1e-07 29.6 0.1 0.011 15.8 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RJW64557.1 - 3.5e-06 27.4 0.8 0.1 13.1 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 RJW64557.1 - 0.00074 19.2 0.6 0.02 14.7 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 RJW64557.1 - 0.0013 18.2 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_7 PF13176.6 RJW64557.1 - 0.0017 18.2 1.3 0.17 12.0 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW64557.1 - 0.0043 17.7 0.4 3.3 8.8 0.1 4.5 5 1 0 5 5 5 1 Tetratricopeptide repeat GED PF02212.18 RJW64557.1 - 0.04 14.1 2.5 0.19 11.9 2.6 2.2 1 1 0 1 1 1 0 Dynamin GTPase effector domain Rx_N PF18052.1 RJW64557.1 - 0.35 11.2 6.1 3 8.2 0.0 4.0 4 1 0 4 4 4 0 Rx N-terminal domain T3SS_basalb_I PF17001.5 RJW64557.1 - 2.4 8.8 5.1 1.5 9.5 0.7 2.9 2 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Ion_trans PF00520.31 RJW64558.1 - 2e-32 112.3 12.4 2.9e-32 111.8 12.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW64558.1 - 1e-06 28.6 9.7 1e-06 28.6 9.7 2.2 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 RJW64558.1 - 1.7e-05 24.8 0.0 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RSN1_7TM PF02714.15 RJW64559.1 - 7.3e-35 120.6 3.2 7.3e-35 120.6 3.2 2.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RJW64559.1 - 3.3e-09 37.2 0.0 9.6e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 RJW64559.1 - 1.9e-08 34.2 0.2 1.9e-08 34.2 0.2 3.6 2 2 0 2 2 2 1 Late exocytosis, associated with Golgi transport Keratin_B2_2 PF13885.6 RJW64559.1 - 1.6 8.8 11.5 0.083 12.9 4.5 2.2 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein CPBP PF02517.16 RJW64559.1 - 6.7 7.2 12.3 0.027 14.8 1.6 2.6 3 1 0 3 3 3 0 CPBP intramembrane metalloprotease Ets PF00178.22 RJW64560.1 - 2.9e-24 85.3 1.9 6.5e-24 84.2 1.9 1.6 1 0 0 1 1 1 1 Ets-domain TolB_N PF04052.13 RJW64560.1 - 0.052 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 TolB amino-terminal domain Hormone_recep PF00104.30 RJW64563.1 - 2.6e-25 89.2 2.4 4.5e-25 88.5 2.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RJW64563.1 - 2.4e-23 82.3 12.8 4.1e-23 81.6 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) adh_short PF00106.25 RJW64564.1 - 1.5e-23 83.3 0.0 4.4e-21 75.2 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW64564.1 - 2e-10 40.6 0.0 9e-09 35.2 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW64564.1 - 0.0027 17.7 0.1 0.0073 16.2 0.1 1.8 1 1 0 1 1 1 1 KR domain Glyco_transf_4 PF13439.6 RJW64564.1 - 0.032 14.2 1.5 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Rft-1 PF04506.13 RJW64565.1 - 1.4e-98 330.9 13.6 2.2e-98 330.3 13.6 1.3 1 0 0 1 1 1 1 Rft protein HLH PF00010.26 RJW64565.1 - 8.7e-14 51.2 0.2 2.5e-13 49.8 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Polysacc_synt_C PF14667.6 RJW64565.1 - 8e-05 22.7 1.7 8e-05 22.7 1.7 3.7 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF4229 PF14012.6 RJW64565.1 - 1.2 9.3 5.0 0.57 10.3 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF4201 PF13870.6 RJW64567.1 - 4.1e-41 140.6 25.1 4.1e-41 140.6 25.1 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF4201) Bacillus_HBL PF05791.11 RJW64567.1 - 0.07 12.9 16.4 0.046 13.5 6.7 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Scaffolding_pro PF11418.8 RJW64567.1 - 4.4 7.9 8.7 15 6.2 0.6 3.7 3 1 0 3 3 3 0 Phi29 scaffolding protein XTBD PF11952.8 RJW64568.1 - 7.7e-16 57.6 0.1 1.6e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD RRM_1 PF00076.22 RJW64569.1 - 5.4e-31 106.2 0.3 1.1e-14 54.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW64569.1 - 1.7e-07 31.2 0.7 0.00026 21.1 0.1 2.8 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RJW64569.1 - 0.016 15.2 0.1 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CSD PF00313.22 RJW64569.1 - 0.088 12.7 0.4 25 4.8 0.1 2.9 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain SspH PF08141.12 RJW64570.1 - 0.024 14.8 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Small acid-soluble spore protein H family Actin PF00022.19 RJW64571.1 - 6.6e-124 413.6 0.0 2.8e-123 411.5 0.0 1.7 1 1 0 1 1 1 1 Actin VGCC_alpha2 PF08473.11 RJW64572.1 - 4.7e-24 85.0 0.0 6.9e-23 81.1 0.0 2.6 1 1 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd dCache_1 PF02743.18 RJW64572.1 - 5.7e-13 49.2 0.1 3.3e-11 43.4 0.0 3.0 3 0 0 3 3 3 1 Cache domain VWA_N PF08399.11 RJW64572.1 - 1.3e-10 41.8 1.1 3.4e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 VWA N-terminal Cache_3-Cache_2 PF17201.4 RJW64572.1 - 8e-05 22.0 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain VWA PF00092.28 RJW64572.1 - 0.00014 22.2 0.2 0.00067 19.9 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 RJW64572.1 - 0.00061 20.4 0.0 0.002 18.7 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 RJW64572.1 - 0.0047 16.9 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Exo_endo_phos PF03372.23 RJW64573.1 - 0.0004 20.0 0.1 0.00068 19.2 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Guanylate_cyc PF00211.20 RJW64574.1 - 2.8e-63 212.9 0.0 5.6e-63 211.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RVT_1 PF00078.27 RJW64574.1 - 3.9e-46 157.3 0.3 1.4e-45 155.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 RJW64574.1 - 1e-35 123.3 0.0 1.9e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW64574.1 - 3e-23 82.5 0.0 7.4e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain CortBP2 PF09727.9 RJW64574.1 - 4.3e-12 46.3 27.7 6.8e-08 32.7 1.3 4.5 2 1 2 4 4 4 3 Cortactin-binding protein-2 ANF_receptor PF01094.28 RJW64574.1 - 0.00061 19.0 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region Exo_endo_phos_2 PF14529.6 RJW64574.1 - 0.0017 18.2 0.0 0.008 16.0 0.0 2.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase HNOBA PF07701.14 RJW64574.1 - 0.0063 16.0 0.9 0.015 14.7 0.9 1.6 1 0 0 1 1 1 1 Heme NO binding associated Dynein_AAA_lid PF17852.1 RJW64574.1 - 0.052 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Glyco_hydro_77 PF02446.17 RJW64574.1 - 0.2 10.5 0.3 0.32 9.8 0.3 1.2 1 0 0 1 1 1 0 4-alpha-glucanotransferase EF-hand_7 PF13499.6 RJW64575.1 - 1.3e-17 64.0 4.9 3.5e-10 40.2 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW64575.1 - 4.5e-12 44.9 4.5 0.00023 20.9 0.1 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 RJW64575.1 - 4.2e-11 41.6 8.0 9.5e-06 24.8 0.4 4.0 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 RJW64575.1 - 3.3e-08 32.6 3.8 0.0007 19.0 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RJW64575.1 - 4.9e-06 26.3 6.6 0.0007 19.4 0.4 3.0 3 1 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW64575.1 - 0.0009 19.5 0.0 0.0027 18.0 0.0 1.8 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Proteasome PF00227.26 RJW64576.1 - 5e-28 97.9 0.0 6.2e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SGTA_dimer PF16546.5 RJW64576.1 - 0.031 14.0 0.2 0.052 13.3 0.2 1.4 1 0 0 1 1 1 0 Homodimerisation domain of SGTA rve PF00665.26 RJW64578.1 - 0.00028 21.0 0.0 0.00055 20.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW64578.1 - 0.0037 17.3 0.1 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Troponin PF00992.20 RJW64579.1 - 4.6e-34 117.6 16.4 4.6e-34 117.6 16.4 2.5 2 1 0 2 2 2 1 Troponin Merozoite_SPAM PF07133.11 RJW64579.1 - 0.088 12.8 21.4 0.073 13.1 20.2 1.5 1 1 0 1 1 1 0 Merozoite surface protein (SPAM) FAM76 PF16046.5 RJW64579.1 - 2.8 7.2 27.0 3.7 6.8 27.0 1.3 1 0 0 1 1 1 0 FAM76 protein Trypsin PF00089.26 RJW64582.1 - 1.9e-14 54.0 0.0 2.3e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin Med8 PF10232.9 RJW64584.1 - 1.6e-32 113.0 2.8 2.2e-32 112.5 2.8 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 RVT_1 PF00078.27 RJW64584.1 - 0.0003 20.4 0.0 0.00094 18.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF16 PF01519.16 RJW64584.1 - 0.068 13.7 0.1 0.41 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 NADH-G_4Fe-4S_3 PF10588.9 RJW64587.1 - 0.019 14.5 3.4 0.38 10.3 0.2 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Aurora-A_bind PF09041.10 RJW64587.1 - 1.3 9.1 4.8 0.63 10.1 0.1 2.7 3 0 0 3 3 3 0 Aurora-A binding Ribosomal_L26 PF16906.5 RJW64589.1 - 1.2e-35 121.8 4.5 2.7e-35 120.7 4.5 1.6 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 RJW64589.1 - 0.0027 17.6 1.9 0.0061 16.5 1.9 1.6 1 0 0 1 1 1 1 KOW motif FA_desaturase PF00487.24 RJW64590.1 - 1.6e-22 80.6 15.9 2.5e-22 79.9 15.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 RJW64590.1 - 0.00016 21.1 0.3 0.00033 20.1 0.3 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) VMA21 PF09446.10 RJW64590.1 - 0.092 12.9 0.8 0.3 11.2 0.3 2.2 2 0 0 2 2 2 0 VMA21-like domain XendoU PF09412.10 RJW64591.1 - 2.4e-31 109.0 0.1 3.3e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU AA_permease_2 PF13520.6 RJW64592.1 - 2.6e-41 141.9 37.6 2.6e-41 141.9 37.6 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 RJW64592.1 - 5.8e-28 97.7 36.1 5.8e-28 97.7 36.1 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RJW64592.1 - 1.1e-14 54.2 5.8 1.1e-14 54.2 5.8 4.3 4 1 0 4 4 4 1 C-terminus of AA_permease DUF4131 PF13567.6 RJW64592.1 - 0.035 13.8 0.1 0.035 13.8 0.1 4.9 4 2 1 5 5 5 0 Domain of unknown function (DUF4131) Alg14 PF08660.11 RJW64593.1 - 2.8e-54 183.7 0.0 5.1e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like RVT_1 PF00078.27 RJW64595.1 - 8.8e-14 51.5 0.0 1.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.22 RJW64597.1 - 2.6e-51 173.4 0.2 2.4e-50 170.3 0.2 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RJW64597.1 - 3.6e-27 95.0 0.1 9.5e-26 90.4 0.1 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW64597.1 - 1.9e-09 37.2 0.1 1e-08 34.8 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW64597.1 - 0.00073 19.1 0.0 0.0077 15.8 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RJW64597.1 - 0.0074 16.4 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 RJW64597.1 - 0.081 12.7 0.0 4.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 RJW64597.1 - 0.1 12.2 0.1 8.8 5.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 RJW64597.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region KH_1 PF00013.29 RJW64599.1 - 8.8e-37 124.8 4.8 2e-16 59.6 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 RJW64599.1 - 9.9e-09 35.0 0.1 0.015 15.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 RJW64599.1 - 3.5e-08 33.1 1.6 0.072 12.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 RJW64599.1 - 0.0001 22.3 1.9 4.5 7.4 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain zf-RING_2 PF13639.6 RJW64600.1 - 6.8e-07 29.5 9.1 1.3e-06 28.6 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 RJW64600.1 - 0.00012 22.0 3.0 0.00022 21.2 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 RJW64600.1 - 0.00025 20.7 4.8 0.00055 19.6 4.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 RJW64600.1 - 0.00033 20.6 8.2 0.00054 19.9 8.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RJW64600.1 - 0.0004 20.6 8.6 0.0011 19.2 8.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RJW64600.1 - 0.0024 17.7 9.0 0.0042 16.9 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 RJW64600.1 - 0.031 14.3 2.4 0.13 12.3 2.4 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 RJW64600.1 - 0.18 11.7 10.1 0.13 12.1 8.3 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW64600.1 - 0.29 11.2 5.8 2 8.5 5.6 2.2 1 1 1 2 2 2 0 RING-type zinc-finger PepSY_TM PF03929.16 RJW64600.1 - 0.43 10.2 11.6 0.35 10.5 9.8 1.7 1 1 1 2 2 2 0 PepSY-associated TM region DUF3488 PF11992.8 RJW64600.1 - 0.74 8.7 11.4 0.024 13.6 4.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) zf-Di19 PF05605.12 RJW64600.1 - 1 9.7 4.8 6.6 7.1 0.2 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SpoVAB PF13782.6 RJW64600.1 - 1.4 9.3 6.8 0.68 10.3 0.9 2.4 2 0 0 2 2 2 0 Stage V sporulation protein AB FANCL_C PF11793.8 RJW64600.1 - 1.4 9.2 9.2 43 4.4 9.2 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-UDP PF14569.6 RJW64600.1 - 2.7 8.2 4.9 1.6 8.9 2.8 1.7 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF2256 PF10013.9 RJW64600.1 - 3.4 7.9 6.0 0.51 10.5 0.6 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) ubiquitin PF00240.23 RJW64601.1 - 2.8e-09 36.6 0.1 5e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 RJW64601.1 - 0.0096 15.8 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 RJW64601.1 - 0.012 16.1 0.1 0.02 15.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain TrbI_Ftype PF09677.10 RJW64604.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF4495 PF14906.6 RJW64606.1 - 0.14 11.2 0.3 0.21 10.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) LRR_9 PF14580.6 RJW64607.1 - 4.5e-13 49.1 8.5 5.4e-11 42.3 5.4 3.3 1 1 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 RJW64607.1 - 2.4e-11 43.7 20.9 0.00025 21.4 2.4 5.5 4 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW64607.1 - 7.2e-08 32.1 7.2 9.3e-06 25.3 0.1 4.0 2 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 RJW64607.1 - 0.049 13.7 2.5 2 8.7 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Bcl-2 PF00452.19 RJW64609.1 - 0.00062 20.4 0.3 0.0059 17.3 0.1 2.4 2 1 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family Pkinase PF00069.25 RJW64610.1 - 2.7e-45 154.8 0.0 3.4e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64610.1 - 2e-32 112.5 0.0 2.6e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW64610.1 - 1.5e-06 27.2 0.0 2.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RVT_1 PF00078.27 RJW64610.1 - 1.2e-05 25.0 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4952 PF16310.5 RJW64610.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) Noggin PF05806.12 RJW64611.1 - 9.9e-28 97.5 9.1 1.6e-27 96.8 0.4 3.4 2 1 1 4 4 4 2 Noggin Anoctamin PF04547.12 RJW64613.1 - 3.5e-153 510.7 10.5 5.2e-153 510.1 10.5 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel RVT_1 PF00078.27 RJW64613.1 - 4.2e-44 150.7 0.0 7.7e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Anoct_dimer PF16178.5 RJW64613.1 - 3.7e-38 131.5 0.1 6.5e-36 124.2 0.1 3.2 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Exo_endo_phos PF03372.23 RJW64613.1 - 0.038 13.5 0.2 0.12 11.8 0.1 1.9 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family DJ-1_PfpI PF01965.24 RJW64614.1 - 2.6e-42 144.4 0.0 3.1e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 RJW64614.1 - 0.00028 20.6 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 RJW64614.1 - 0.0023 17.6 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 RJW64614.1 - 0.06 13.1 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Tyr-DNA_phospho PF06087.12 RJW64615.1 - 2.3e-116 389.2 0.0 3e-116 388.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-CCHH PF10283.9 RJW64615.1 - 1.4e-12 47.3 6.1 3.7e-12 46.0 6.1 1.7 1 0 0 1 1 1 1 PBZ domain EF-hand_7 PF13499.6 RJW64616.1 - 6.3e-23 81.0 4.0 1.1e-15 57.9 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW64616.1 - 1e-20 71.7 10.5 5.3e-07 28.7 0.9 3.9 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RJW64616.1 - 6.5e-20 69.3 1.5 8.8e-06 25.3 0.2 4.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 RJW64616.1 - 4e-17 60.8 2.1 5.6e-05 22.4 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RJW64616.1 - 1e-15 57.3 3.9 3.7e-07 29.9 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW64616.1 - 0.00012 22.4 0.7 0.061 13.6 0.1 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW64616.1 - 0.00087 19.2 2.0 1 9.4 0.1 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RJW64616.1 - 0.003 17.7 0.0 0.032 14.4 0.0 2.3 2 1 0 2 2 2 1 Dockerin type I domain MecA_N PF05223.11 RJW64616.1 - 0.027 14.7 0.2 0.33 11.2 0.1 2.2 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain EF-hand_10 PF14788.6 RJW64616.1 - 0.029 14.2 0.9 19 5.2 0.2 3.2 2 1 1 3 3 3 0 EF hand EF-hand_9 PF14658.6 RJW64616.1 - 0.098 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Caleosin PF05042.13 RJW64616.1 - 0.2 11.6 1.1 38 4.1 0.1 3.1 1 1 1 3 3 3 0 Caleosin related protein SRP54 PF00448.22 RJW64617.1 - 1.5e-47 161.8 0.2 1.6e-46 158.5 0.2 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 RJW64617.1 - 3.5e-07 30.5 13.1 5.9e-07 29.7 13.1 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 RJW64617.1 - 8e-06 26.0 0.0 2.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 RJW64617.1 - 0.00024 21.5 0.3 0.00083 19.8 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 RJW64617.1 - 0.00038 20.5 0.0 0.0019 18.2 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 RJW64617.1 - 0.00057 19.0 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 RJW64617.1 - 0.009 15.9 0.0 0.047 13.6 0.0 2.2 1 1 0 1 1 1 1 NTPase AAA_30 PF13604.6 RJW64617.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RJW64617.1 - 0.015 15.5 0.0 0.069 13.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain ArsA_ATPase PF02374.15 RJW64617.1 - 0.022 14.0 0.0 0.082 12.1 0.0 1.9 1 1 1 2 2 2 0 Anion-transporting ATPase Fer4_NifH PF00142.18 RJW64617.1 - 0.031 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 RJW64617.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RJW64617.1 - 0.083 12.6 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RJW64617.1 - 0.1 12.5 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 RJW64617.1 - 0.12 12.5 0.4 0.97 9.5 0.4 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sec7 PF01369.20 RJW64618.1 - 4.3e-41 140.6 0.1 6.9e-41 139.9 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 RJW64618.1 - 1.1e-32 112.9 0.1 3.7e-20 72.5 0.0 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 RJW64618.1 - 3.1e-06 27.7 0.1 0.007 16.9 0.0 2.8 3 0 0 3 3 3 2 PH domain zf-C4 PF00105.18 RJW64619.1 - 4.8e-29 100.6 18.0 1.1e-28 99.5 18.0 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Astro_capsid_p PF12226.8 RJW64619.1 - 0.076 12.2 3.8 0.12 11.6 3.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DP PF08781.10 RJW64621.1 - 1.2e-36 125.7 2.4 1.2e-25 90.0 0.0 2.3 2 0 0 2 2 2 2 Transcription factor DP E2F_TDP PF02319.20 RJW64621.1 - 2.2e-19 69.3 1.2 2.6e-19 69.0 0.2 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Peptidase_M24 PF00557.24 RJW64622.1 - 3.9e-43 147.6 0.0 4.6e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M41 PF01434.18 RJW64623.1 - 8.1e-39 133.4 0.0 1.4e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 RJW64623.1 - 4.2e-38 130.8 0.1 2e-37 128.6 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW64623.1 - 1.2e-11 44.2 0.0 4.4e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RJW64623.1 - 4.4e-05 23.9 1.4 0.0084 16.5 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 RJW64623.1 - 0.0001 22.3 0.0 0.00056 19.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RJW64623.1 - 0.00015 22.1 0.1 0.062 13.6 0.0 3.5 1 1 2 3 3 3 1 AAA domain AAA_17 PF13207.6 RJW64623.1 - 0.0013 19.1 0.0 0.0056 17.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RJW64623.1 - 0.0014 18.4 0.1 0.0089 15.8 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 RJW64623.1 - 0.0021 18.3 0.0 0.0061 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RJW64623.1 - 0.0057 15.9 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 RJW64623.1 - 0.013 15.3 1.7 0.091 12.5 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein TsaE PF02367.17 RJW64623.1 - 0.024 14.6 0.1 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RJW64623.1 - 0.042 13.0 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 RJW64623.1 - 0.056 13.4 0.4 1.8 8.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 RJW64623.1 - 0.065 13.8 0.1 0.21 12.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 RJW64623.1 - 0.07 13.2 0.0 0.29 11.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) DnaB_bind PF10410.9 RJW64623.1 - 0.11 12.7 0.0 13 6.1 0.0 2.8 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase AAA_6 PF12774.7 RJW64623.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region NAD_binding_1 PF00175.21 RJW64623.1 - 0.16 12.6 0.0 2.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Mg_chelatase PF01078.21 RJW64623.1 - 0.18 11.2 0.7 0.34 10.3 0.2 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 RJW64623.1 - 0.26 11.6 0.6 1.6 9.0 0.2 2.4 3 0 0 3 3 3 0 AAA domain UCH PF00443.29 RJW64625.1 - 4.5e-42 144.3 0.0 1e-41 143.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW64625.1 - 2.2e-15 57.1 0.2 2.3e-14 53.7 0.2 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FlhC PF05280.11 RJW64625.1 - 0.079 12.7 0.3 0.079 12.7 0.3 2.1 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) zf-4CXXC_R1 PF10497.9 RJW64625.1 - 2 8.7 8.7 0.65 10.2 4.8 2.2 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 7tm_1 PF00001.21 RJW64626.1 - 2.1e-20 73.1 14.3 3.8e-20 72.3 14.3 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW64626.1 - 2.4e-13 50.1 24.3 1.4e-09 37.7 13.5 3.1 2 1 2 4 4 4 2 Serpentine type 7TM GPCR chemoreceptor Srw UPF0542 PF15086.6 RJW64626.1 - 0.14 12.1 0.4 2.9 7.9 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 NIF PF03031.18 RJW64627.1 - 1.5e-09 37.8 0.2 2.8e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Pkinase PF00069.25 RJW64629.1 - 1.5e-64 217.9 0.0 2e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64629.1 - 5.3e-49 166.8 0.0 7.7e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 RJW64629.1 - 1.5e-17 63.4 0.3 2.7e-17 62.5 0.3 1.5 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Pkinase_fungal PF17667.1 RJW64629.1 - 4.4e-08 32.3 0.0 7.5e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF4952 PF16310.5 RJW64629.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) Arrestin_C PF02752.22 RJW64630.1 - 2.7e-05 24.6 0.0 0.00019 21.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain NAC PF01849.18 RJW64632.1 - 2.3e-24 85.1 0.2 4.1e-24 84.3 0.2 1.4 1 0 0 1 1 1 1 NAC domain UPRTase PF14681.6 RJW64634.1 - 3.3e-68 229.2 0.0 5.5e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 RJW64634.1 - 1.1e-54 185.2 0.0 1.5e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 RJW64634.1 - 2e-05 25.1 0.0 3.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 RJW64634.1 - 3e-05 23.8 0.7 0.025 14.3 0.0 2.3 1 1 0 2 2 2 2 Cytidylate kinase AAA_33 PF13671.6 RJW64634.1 - 0.00052 20.2 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 RJW64634.1 - 0.00074 19.2 0.1 0.013 15.2 0.1 2.3 1 1 0 1 1 1 1 Dephospho-CoA kinase CPT PF07931.12 RJW64634.1 - 0.00093 19.1 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 RJW64634.1 - 0.0021 18.5 0.0 1.7 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RJW64634.1 - 0.028 13.7 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RL10P_insert PF17777.1 RJW64634.1 - 0.097 12.7 0.0 0.65 10.0 0.0 2.3 2 1 1 3 3 3 0 Insertion domain in 60S ribosomal protein L10P DUF999 PF06198.11 RJW64635.1 - 0.035 14.1 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF999) Hormone_recep PF00104.30 RJW64636.1 - 6.7e-17 61.8 0.1 5.6e-16 58.7 0.1 2.2 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor RabGAP-TBC PF00566.18 RJW64637.1 - 4.1e-16 59.3 0.4 6.5e-16 58.6 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FH2 PF02181.23 RJW64638.1 - 7e-33 114.3 4.5 5.3e-32 111.3 4.5 2.2 1 1 0 1 1 1 1 Formin Homology 2 Domain Claudin_2 PF13903.6 RJW64639.1 - 3.7e-06 26.8 0.4 3.7e-06 26.8 0.4 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Tetraspanin PF00335.20 RJW64639.1 - 0.0067 16.2 1.2 0.036 13.8 0.3 2.1 2 0 0 2 2 2 1 Tetraspanin family Clc-like PF07062.12 RJW64639.1 - 0.023 14.1 0.8 0.033 13.7 0.1 1.6 2 0 0 2 2 2 0 Clc-like MARVEL PF01284.23 RJW64639.1 - 0.026 14.6 7.3 0.076 13.0 7.3 1.9 1 1 0 1 1 1 0 Membrane-associating domain SUR7 PF06687.12 RJW64639.1 - 0.026 14.2 0.1 0.069 12.8 0.0 1.6 1 1 1 2 2 2 0 SUR7/PalI family DUF4293 PF14126.6 RJW64639.1 - 0.026 14.8 0.1 0.026 14.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Wzy_C PF04932.15 RJW64639.1 - 0.22 11.1 4.3 0.17 11.5 1.9 1.9 2 0 0 2 2 2 0 O-Antigen ligase DUF4064 PF13273.6 RJW64639.1 - 0.47 10.8 8.3 0.15 12.4 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF2892 PF11127.8 RJW64639.1 - 0.57 10.3 10.6 0.2 11.7 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) DUF4131 PF13567.6 RJW64639.1 - 0.73 9.5 6.1 0.096 12.3 1.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) COPI_assoc PF08507.10 RJW64639.1 - 0.86 9.7 6.0 9.9 6.2 3.5 2.4 2 1 0 2 2 2 0 COPI associated protein DUF5305 PF17231.2 RJW64639.1 - 0.89 8.9 2.5 2.4 7.5 0.1 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5305) Phage_holin_5_2 PF16079.5 RJW64639.1 - 1.3 9.4 6.6 0.81 10.1 0.1 2.6 3 0 0 3 3 2 0 Phage holin family Hol44, in holin superfamily V DUF308 PF03729.13 RJW64639.1 - 1.3 9.4 15.0 0.17 12.2 4.4 2.5 3 0 0 3 3 2 0 Short repeat of unknown function (DUF308) DUF1275 PF06912.11 RJW64639.1 - 2.4 8.0 13.3 0.31 10.9 6.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1275) RVT_1 PF00078.27 RJW64640.1 - 1e-31 110.2 0.0 1.7e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GRP PF07172.11 RJW64641.1 - 1.1 10.0 12.5 0.47 11.2 9.7 1.8 2 0 0 2 2 2 0 Glycine rich protein family BRI3BP PF14965.6 RJW64642.1 - 0.11 12.0 2.0 3 7.3 0.2 2.8 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Leu_zip PF15294.6 RJW64642.1 - 0.38 10.2 46.7 0.021 14.3 7.4 3.5 1 1 3 4 4 4 0 Leucine zipper Fcf2 PF08698.11 RJW64642.1 - 0.97 9.9 8.1 0.46 10.9 3.2 2.7 2 1 0 2 2 2 0 Fcf2 pre-rRNA processing Myotub-related PF06602.14 RJW64643.1 - 3.7e-74 249.8 0.0 1.4e-41 142.6 0.0 2.8 3 1 0 3 3 3 2 Myotubularin-like phosphatase domain SAM_3 PF18016.1 RJW64643.1 - 0.13 12.1 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) zf-C2H2 PF00096.26 RJW64644.1 - 2.3e-17 62.4 26.8 0.00019 21.7 0.2 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW64644.1 - 3.5e-13 49.1 24.7 0.0027 18.4 0.3 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW64644.1 - 2.1e-05 24.7 27.0 0.00046 20.5 1.2 5.7 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_3rep PF18868.1 RJW64644.1 - 0.00023 21.9 2.4 0.44 11.2 0.0 3.1 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 RJW64644.1 - 0.0018 18.0 8.1 0.11 12.2 0.4 3.8 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 RJW64644.1 - 0.62 10.4 9.6 0.37 11.1 1.8 3.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 RJW64644.1 - 0.7 10.2 18.1 0.13 12.5 8.3 3.3 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RJW64644.1 - 0.73 9.9 19.8 1.4 9.0 2.6 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger DUF1677 PF07911.13 RJW64644.1 - 1.2 9.5 3.7 2.9 8.3 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Zn-ribbon_8 PF09723.10 RJW64644.1 - 1.5 9.0 11.8 0.28 11.3 2.6 3.0 3 0 0 3 3 3 0 Zinc ribbon domain ADK_lid PF05191.14 RJW64644.1 - 2 8.5 9.4 0.36 10.9 0.1 3.3 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-CCCH_2 PF14608.6 RJW64646.1 - 3.6e-10 39.9 47.3 0.00022 21.6 4.3 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger PWI PF01480.17 RJW64646.1 - 0.00023 21.4 0.1 0.00062 20.0 0.1 1.7 1 0 0 1 1 1 1 PWI domain DUF4422 PF14393.6 RJW64646.1 - 0.0051 16.7 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4422) Nab2p_Zf1 PF18260.1 RJW64646.1 - 0.021 14.7 8.5 0.066 13.1 0.4 2.9 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf_CCCH_4 PF18345.1 RJW64646.1 - 4.4 7.5 29.4 0.12 12.4 1.6 6.7 6 1 0 6 6 6 0 Zinc finger domain RasGEF PF00617.19 RJW64647.1 - 1.6e-15 57.8 1.2 3.7e-15 56.6 0.2 2.2 2 1 0 2 2 2 1 RasGEF domain DUF1126 PF06565.12 RJW64650.1 - 0.0086 15.9 0.9 0.12 12.2 0.1 3.1 2 1 2 4 4 4 1 DUF1126 PH-like domain Cystatin PF00031.21 RJW64650.1 - 0.025 14.8 0.3 1.7 8.9 0.0 3.7 4 0 0 4 4 4 0 Cystatin domain DUF667 PF05018.13 RJW64651.1 - 1.7e-10 40.9 0.3 3.8e-10 39.8 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF667) OCRE PF17780.1 RJW64651.1 - 0.014 15.4 0.4 0.028 14.5 0.4 1.4 1 0 0 1 1 1 0 OCRE domain MICSWaP PF17018.5 RJW64652.1 - 0.12 11.9 2.5 0.25 10.9 0.2 2.3 3 0 0 3 3 3 0 Spore wall protein FAM110_N PF14161.6 RJW64652.1 - 0.13 12.5 0.1 0.49 10.6 0.1 2.0 3 0 0 3 3 3 0 Centrosome-associated N terminus I_LWEQ PF01608.17 RJW64653.1 - 4.4e-44 150.4 1.0 4.4e-44 150.4 1.0 12.4 9 4 4 13 13 13 2 I/LWEQ domain Pdase_M17_N2 PF18295.1 RJW64653.1 - 0.38 11.0 6.7 1.6 9.0 3.4 3.9 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 DUF2277 PF10041.9 RJW64653.1 - 0.71 10.2 3.6 11 6.5 0.0 4.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) Sec8_exocyst PF04048.14 RJW64653.1 - 1.4 8.8 10.8 9.1 6.2 0.4 5.3 6 0 0 6 6 6 0 Sec8 exocyst complex component specific domain DUF5344 PF17279.2 RJW64653.1 - 9.5 6.9 7.5 29 5.3 0.2 5.3 4 0 0 4 4 4 0 Family of unknown function (DUF5344) SLAIN PF15301.6 RJW64654.1 - 1.8e-06 27.5 4.1 0.00064 19.1 0.1 2.9 2 2 1 3 3 3 2 SLAIN motif-containing family DEAD PF00270.29 RJW64655.1 - 1.2e-34 119.6 0.0 1.9e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RJW64655.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PfkB PF00294.24 RJW64656.1 - 2.4e-49 168.3 0.0 3e-35 122.0 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DUF4817 PF16087.5 RJW64657.1 - 4.3e-09 36.1 0.0 8.6e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) DDE_3 PF13358.6 RJW64657.1 - 8.3e-06 25.6 0.0 2e-05 24.4 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease PAX PF00292.18 RJW64657.1 - 0.022 14.7 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 'Paired box' domain HTH_Tnp_Tc3_2 PF01498.18 RJW64657.1 - 0.044 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Transposase Exo_endo_phos PF03372.23 RJW64660.1 - 2.2e-05 24.1 0.0 7.9e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PI-PLC-X PF00388.19 RJW64661.1 - 2.1e-62 209.0 0.0 4.4e-62 208.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PH_14 PF17787.1 RJW64661.1 - 7.9e-35 119.6 0.0 2.2e-34 118.1 0.0 1.8 2 0 0 2 2 2 1 PH domain EF-hand_like PF09279.11 RJW64661.1 - 5.6e-09 36.4 1.7 1.3e-08 35.2 0.9 2.0 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like PDZ_6 PF17820.1 RJW64662.1 - 5.6e-09 35.7 0.3 1.2e-08 34.7 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW64662.1 - 6.5e-08 32.8 0.1 1.2e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW64662.1 - 8.9e-05 22.7 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain zf-RING_2 PF13639.6 RJW64663.1 - 2.1e-14 53.6 31.0 3.7e-10 40.0 2.0 3.9 3 0 0 3 3 3 2 Ring finger domain zf-RING_11 PF17123.5 RJW64663.1 - 1.2e-07 31.3 1.3 1.2e-07 31.3 1.3 4.2 4 0 0 4 4 4 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RJW64663.1 - 4.1e-06 26.5 2.1 4.1e-06 26.5 2.1 4.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SWIM PF04434.17 RJW64663.1 - 2e-05 24.1 0.5 5.5e-05 22.7 0.5 1.8 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.7 RJW64663.1 - 5.9e-05 23.3 4.7 5.9e-05 23.3 4.7 3.7 3 2 0 3 3 2 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 RJW64663.1 - 0.00025 20.6 0.5 0.00025 20.6 0.5 4.5 5 1 1 6 6 5 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 RJW64663.1 - 0.00029 20.7 21.4 0.00074 19.3 0.8 4.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW64663.1 - 0.0014 18.6 20.8 0.0015 18.5 2.6 4.5 3 1 1 4 4 4 2 RING-type zinc-finger FANCL_C PF11793.8 RJW64663.1 - 0.0015 18.7 18.9 0.0028 17.8 3.5 3.0 3 0 0 3 3 2 2 FANCL C-terminal domain zf-ANAPC11 PF12861.7 RJW64663.1 - 0.092 12.8 14.1 0.081 13.0 0.6 3.5 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UBR PF02207.20 RJW64663.1 - 0.27 11.4 16.3 0.024 14.8 10.0 2.6 2 1 0 2 2 1 0 Putative zinc finger in N-recognin (UBR box) Prok-RING_4 PF14447.6 RJW64663.1 - 0.73 9.7 22.6 1 9.3 1.8 5.4 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 RJW64663.1 - 0.79 9.7 19.1 2 8.4 0.9 4.7 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 DUF2175 PF09943.9 RJW64663.1 - 1.9 8.8 4.6 0.41 11.0 0.5 2.1 2 0 0 2 2 1 0 Uncharacterized protein conserved in archaea (DUF2175) ZZ PF00569.17 RJW64663.1 - 4.6 7.1 16.8 0.45 10.4 10.7 2.6 2 1 0 2 2 2 0 Zinc finger, ZZ type PHD PF00628.29 RJW64663.1 - 5.9 6.9 27.1 0.088 12.7 4.4 3.9 3 1 1 4 4 4 0 PHD-finger RecR PF02132.15 RJW64663.1 - 9.8 5.8 15.2 3.4 7.3 0.5 4.5 4 0 0 4 4 4 0 RecR protein CDC27 PF09507.10 RJW64664.1 - 1.5e-09 37.8 23.6 2.3e-09 37.2 23.4 1.3 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Polyoma_agno PF01736.16 RJW64664.1 - 0.066 12.9 1.2 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Polyomavirus agnoprotein Filo_glycop PF01611.16 RJW64664.1 - 1.4 7.8 7.6 2.1 7.2 7.6 1.2 1 0 0 1 1 1 0 Filovirus glycoprotein Ndc1_Nup PF09531.10 RJW64664.1 - 2.2 6.9 5.7 2.8 6.5 5.7 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPT6_acidic PF14632.6 RJW64664.1 - 7.8 7.2 9.1 13 6.4 4.9 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 F_actin_cap_B PF01115.17 RJW64665.1 - 8.2e-46 156.6 0.0 1.1e-45 156.2 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit zf-C2H2 PF00096.26 RJW64666.1 - 0.015 15.7 1.1 0.015 15.7 1.1 11.9 12 3 0 12 12 12 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW64666.1 - 0.24 12.4 0.1 0.066 14.1 1.5 14.1 14 0 0 14 14 14 0 C2H2-type zinc finger FOXP-CC PF16159.5 RJW64666.1 - 0.24 12.0 6.3 18 6.1 0.1 4.9 4 0 0 4 4 4 0 FOXP coiled-coil domain DUF3039 PF11238.8 RJW64666.1 - 0.39 10.5 4.8 0.44 10.3 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3039) zf-C2HC_2 PF13913.6 RJW64666.1 - 2.8 8.0 8.8 0.42 10.6 0.5 3.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_12 PF18658.1 RJW64666.1 - 3.6 7.2 30.1 2.3 7.9 0.3 7.0 8 0 0 8 8 8 0 Zinc-finger C2H2-type Glyco_tran_28_C PF04101.16 RJW64667.1 - 8.1e-14 51.9 0.0 1.1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Tubulin PF00091.25 RJW64668.1 - 1e-38 133.5 0.0 1.3e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 RJW64668.1 - 0.00051 19.3 0.0 0.00075 18.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Arrestin_N PF00339.29 RJW64669.1 - 9.8e-30 103.5 0.0 3.4e-13 49.9 0.0 3.1 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RJW64669.1 - 2.6e-15 57.0 0.2 4.3e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain zf-C2H2 PF00096.26 RJW64670.1 - 1.6e-06 28.3 10.0 5.5e-05 23.4 1.2 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW64670.1 - 0.00066 20.0 0.7 0.00066 20.0 0.7 5.2 6 0 0 6 6 6 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW64670.1 - 0.0064 17.2 1.1 0.0064 17.2 1.1 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger GAGA PF09237.11 RJW64670.1 - 0.061 13.1 6.3 0.96 9.3 2.0 2.6 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.7 RJW64670.1 - 0.17 12.4 0.4 0.17 12.4 0.4 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 RJW64670.1 - 9.6 5.9 8.8 20 4.9 0.1 3.4 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3509 PF12021.8 RJW64671.1 - 0.037 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Helicase_C PF00271.31 RJW64672.1 - 4.3e-05 23.8 0.3 0.00012 22.4 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Use1 PF09753.9 RJW64672.1 - 0.011 15.5 6.4 0.012 15.4 6.4 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 MipZ PF09140.11 RJW64672.1 - 0.017 14.4 0.9 0.025 13.9 0.9 1.3 1 0 0 1 1 1 0 ATPase MipZ Trimer_CC PF08954.11 RJW64672.1 - 0.025 14.1 0.1 0.025 14.1 0.1 2.4 2 1 1 3 3 3 0 Trimerisation motif Aldedh PF00171.22 RJW64674.1 - 5.2e-102 341.7 0.0 5.8e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GD_AH_C PF04295.13 RJW64674.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus Peptidase_A3 PF02160.15 RJW64675.1 - 0.18 11.3 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Vps39_1 PF10366.9 RJW64678.1 - 1.7e-22 79.7 6.1 4.5e-21 75.2 0.7 4.1 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 RJW64678.1 - 3.1e-14 53.3 0.3 8e-14 52.0 0.3 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 RJW64678.1 - 3.1e-13 49.8 2.4 3e-05 23.9 0.1 4.2 4 0 0 4 4 4 2 Region in Clathrin and VPS CNH PF00780.22 RJW64678.1 - 2.3e-09 37.2 0.0 0.00046 19.9 0.0 2.3 2 0 0 2 2 2 2 CNH domain AlkA_N PF06029.11 RJW64678.1 - 0.0015 18.8 0.0 0.0043 17.3 0.0 1.7 1 0 0 1 1 1 1 AlkA N-terminal domain CPSF_A PF03178.15 RJW64679.1 - 1.6e-62 211.7 0.0 4.2e-62 210.3 0.0 1.7 1 1 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 RJW64679.1 - 2.7e-21 75.8 0.0 6.6e-14 51.4 0.0 3.2 3 0 0 3 3 3 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term Glyco_hydro2_C5 PF18565.1 RJW64679.1 - 0.18 11.7 0.0 0.57 10.1 0.0 1.8 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 NAC PF01849.18 RJW64680.1 - 0.0003 20.7 0.0 0.92 9.5 0.0 2.1 2 0 0 2 2 2 2 NAC domain Lantibiotic_a PF14867.6 RJW64680.1 - 0.0039 16.9 0.1 3.8 7.3 0.0 2.3 2 0 0 2 2 2 2 Lantibiotic alpha Metallothio_Cad PF07846.11 RJW64680.1 - 0.035 14.2 2.0 7 6.9 0.1 2.4 2 0 0 2 2 2 0 Metallothionein family Asp_decarbox PF02261.16 RJW64680.1 - 0.062 13.2 0.0 14 5.7 0.0 2.1 2 0 0 2 2 2 0 Aspartate decarboxylase ImpE PF07024.13 RJW64681.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 ImpE protein RhoGAP PF00620.27 RJW64682.1 - 1.4e-13 51.0 0.0 4.2e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain Laminin_II PF06009.12 RJW64682.1 - 0.11 12.5 3.3 0.31 11.0 0.3 2.9 3 0 0 3 3 3 0 Laminin Domain II Occludin_ELL PF07303.13 RJW64682.1 - 5.8 7.7 9.9 73 4.2 0.0 4.1 4 0 0 4 4 4 0 Occludin homology domain Cactin_mid PF10312.9 RJW64683.1 - 2.1e-58 197.4 0.7 2.1e-58 197.4 0.7 2.5 3 1 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 RJW64683.1 - 1.1e-55 186.9 9.5 2.4e-55 185.8 9.5 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Tim17 PF02466.19 RJW64683.1 - 8.1e-12 45.5 0.1 2e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SF3A2 PF16835.5 RJW64683.1 - 0.082 13.3 0.0 0.33 11.3 0.0 2.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Exo70 PF03081.15 RJW64685.1 - 8.7e-89 298.2 4.3 8.7e-89 298.2 4.3 2.4 2 0 0 2 2 2 1 Exo70 exocyst complex subunit RVT_1 PF00078.27 RJW64685.1 - 5.7e-73 245.1 0.0 1.6e-38 132.5 0.0 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Dus PF01207.17 RJW64685.1 - 6.3e-45 153.6 1.5 2.8e-29 102.2 0.0 3.0 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) Molybdopterin PF00384.22 RJW64685.1 - 0.0094 15.0 0.0 4.2 6.2 0.0 2.2 2 0 0 2 2 2 2 Molybdopterin oxidoreductase DUF2656 PF10847.8 RJW64685.1 - 0.078 13.1 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) DUF3084 PF11283.8 RJW64685.1 - 0.081 12.9 0.8 18 5.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) GrpE PF01025.19 RJW64685.1 - 0.33 10.6 1.8 1.2 8.8 1.8 2.0 1 0 0 1 1 1 0 GrpE Sec34 PF04136.15 RJW64685.1 - 1.1 9.1 4.9 3 7.7 4.9 1.7 1 0 0 1 1 1 0 Sec34-like family AAA PF00004.29 RJW64686.1 - 2.8e-12 47.2 0.0 5.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW64686.1 - 3.7e-11 43.7 0.1 9e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RJW64686.1 - 5.7e-10 39.6 0.1 1.4e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 RJW64686.1 - 7.5e-09 35.4 0.1 7.5e-09 35.4 0.1 2.2 3 0 0 3 3 1 1 CDC6, C terminal winged helix domain TniB PF05621.11 RJW64686.1 - 3e-05 23.5 0.0 5.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_5 PF07728.14 RJW64686.1 - 0.00011 22.2 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_10 PF17872.1 RJW64686.1 - 0.00017 21.7 0.1 0.0007 19.7 0.2 1.9 2 0 0 2 2 2 1 AAA lid domain AAA_19 PF13245.6 RJW64686.1 - 0.0025 18.2 0.1 0.0095 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RJW64686.1 - 0.0032 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 RJW64686.1 - 0.0069 16.1 0.2 0.091 12.5 0.2 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 RJW64686.1 - 0.0096 15.7 0.2 1.1 9.0 0.0 2.9 2 1 1 3 3 3 1 IstB-like ATP binding protein NACHT PF05729.12 RJW64686.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RVT_1 PF00078.27 RJW64686.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF815 PF05673.13 RJW64686.1 - 0.024 13.8 0.0 0.056 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ORC5_C PF14630.6 RJW64686.1 - 0.033 13.7 0.3 0.18 11.3 0.3 2.1 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DEAD PF00270.29 RJW64686.1 - 0.044 13.5 0.4 2.2 8.0 0.4 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase TIP49 PF06068.13 RJW64686.1 - 0.071 12.3 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain DEAD PF00270.29 RJW64688.1 - 1.1e-46 158.8 0.1 2.2e-46 157.8 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW64688.1 - 6.3e-26 90.9 0.0 3.1e-25 88.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW64688.1 - 2.2e-07 31.0 0.0 5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SKIP_SNW PF02731.15 RJW64688.1 - 0.0096 15.6 1.0 0.017 14.8 1.0 1.3 1 0 0 1 1 1 1 SKIP/SNW domain Terminase_6 PF03237.15 RJW64688.1 - 0.046 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Terminase-like family CMS1 PF14617.6 RJW64688.1 - 0.052 12.9 8.2 0.056 12.8 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit zf-C2H2 PF00096.26 RJW64690.1 - 1.2e-10 41.2 32.2 0.00029 21.1 6.0 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW64690.1 - 1.6e-07 31.5 28.7 0.00031 21.3 4.9 4.1 4 0 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW64690.1 - 0.00047 20.5 3.4 0.00047 20.5 3.4 4.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 RJW64690.1 - 0.029 14.7 0.4 0.029 14.7 0.4 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SIR2 PF02146.17 RJW64690.1 - 0.052 13.5 4.0 0.033 14.1 1.7 1.9 3 0 0 3 3 3 0 Sir2 family XPA_N PF01286.18 RJW64690.1 - 0.21 11.7 8.1 0.33 11.0 0.2 3.0 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_jaz PF12171.8 RJW64690.1 - 0.72 10.2 13.2 3.4 8.0 0.8 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW64690.1 - 1.3 9.5 12.5 2.6 8.5 2.9 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RJW64690.1 - 3.2 8.1 19.4 2 8.8 11.7 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 RJW64690.1 - 4.4 7.7 18.4 5.5 7.4 0.8 2.7 2 1 1 3 3 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 RJW64690.1 - 4.6 7.4 33.2 0.95 9.5 7.4 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger UBX PF00789.20 RJW64692.1 - 6.2e-15 55.2 0.0 1.5e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain SOBP PF15279.6 RJW64692.1 - 0.41 11.2 5.3 0.53 10.9 5.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3827 PF12877.7 RJW64692.1 - 1.4 7.2 9.4 1.9 6.8 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Prominin PF05478.11 RJW64692.1 - 3.4 5.5 5.2 4.1 5.2 5.2 1.0 1 0 0 1 1 1 0 Prominin Atg14 PF10186.9 RJW64692.1 - 8 5.4 19.8 11 5.0 19.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GREB1 PF15782.5 RJW64692.1 - 8.8 3.3 8.5 10 3.0 8.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer YABBY PF04690.13 RJW64692.1 - 9.9 6.7 8.4 16 6.0 8.4 1.4 1 1 0 1 1 1 0 YABBY protein Ion_trans_2 PF07885.16 RJW64693.1 - 4.1e-26 90.7 11.6 2.3e-18 65.9 4.1 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 RJW64693.1 - 0.00031 20.0 2.8 0.00031 20.0 2.8 1.5 2 0 0 2 2 2 1 Ion transport protein DUF4448 PF14610.6 RJW64693.1 - 0.05 13.4 0.3 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF21 PF01595.20 RJW64693.1 - 0.073 12.8 1.1 0.15 11.8 1.1 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF3377 PF11857.8 RJW64693.1 - 0.088 12.8 0.2 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) EGF_2 PF07974.13 RJW64695.1 - 0.096 13.1 1.3 0.28 11.6 1.3 1.7 1 1 0 1 1 1 0 EGF-like domain Pkinase PF00069.25 RJW64696.1 - 2.4e-24 86.1 0.0 2e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64696.1 - 2.2e-18 66.5 0.0 3.3e-17 62.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase UPF0302 PF08864.10 RJW64696.1 - 0.033 14.3 0.4 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 UPF0302 domain Kdo PF06293.14 RJW64696.1 - 0.06 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RJW64697.1 - 1.8e-72 243.9 0.0 2.3e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64697.1 - 2e-34 119.0 0.0 2.7e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW64697.1 - 4.2e-09 36.1 0.0 2.1e-07 30.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 RJW64697.1 - 0.00011 21.6 0.1 0.00028 20.3 0.0 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RJW64697.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 RJW64697.1 - 0.0088 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RJW64697.1 - 0.017 15.1 0.1 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S13_N PF08069.12 RJW64697.1 - 0.11 12.6 0.5 0.41 10.7 0.0 2.2 2 1 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain SAM_2 PF07647.17 RJW64698.1 - 1.3e-09 38.0 0.5 3.4e-05 23.9 0.0 3.8 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RJW64698.1 - 3e-08 34.0 0.1 0.14 12.6 0.0 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) HAUS-augmin3 PF14932.6 RJW64698.1 - 0.0055 16.3 3.3 0.011 15.3 3.3 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 SAM_PNT PF02198.16 RJW64698.1 - 0.0077 16.2 0.1 0.29 11.1 0.0 2.6 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain YkyA PF10368.9 RJW64698.1 - 0.0089 15.7 3.1 0.017 14.8 3.1 1.4 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein IFT57 PF10498.9 RJW64698.1 - 0.009 15.0 1.7 0.015 14.3 1.7 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Filament PF00038.21 RJW64698.1 - 0.013 15.1 2.7 0.022 14.3 2.7 1.3 1 0 0 1 1 1 0 Intermediate filament protein APG6_N PF17675.1 RJW64698.1 - 0.021 15.4 4.7 0.044 14.3 4.7 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Dsh_C PF12316.8 RJW64698.1 - 0.021 15.2 0.5 0.021 15.2 0.5 2.0 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal CENP-F_leu_zip PF10473.9 RJW64698.1 - 0.081 12.9 5.4 0.18 11.9 5.4 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 RJW64698.1 - 0.091 12.8 4.0 0.21 11.7 4.0 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 RJW64698.1 - 0.12 12.5 5.2 0.16 12.1 3.6 2.1 2 0 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein Jnk-SapK_ap_N PF09744.9 RJW64698.1 - 0.25 11.5 5.7 0.6 10.3 5.7 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 RJW64698.1 - 0.92 9.8 6.3 2.4 8.5 1.9 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snapin_Pallidin PF14712.6 RJW64698.1 - 5 7.6 8.0 14 6.2 8.0 1.7 1 0 0 1 1 1 0 Snapin/Pallidin Glyco_hydro_47 PF01532.20 RJW64699.1 - 5.1e-109 365.2 0.0 7.1e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Endosulfine PF04667.17 RJW64701.1 - 8.9e-12 45.0 0.2 1.6e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ribosomal_L1 PF00687.21 RJW64703.1 - 7.4e-44 149.9 3.5 8.5e-44 149.7 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family GHL13 PF14883.6 RJW64703.1 - 0.0014 17.8 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 13 TetR PF13972.6 RJW64703.1 - 0.14 11.9 0.4 0.26 11.0 0.1 1.5 2 0 0 2 2 2 0 Bacterial transcriptional repressor Kelch_5 PF13854.6 RJW64704.1 - 5.7e-35 118.8 0.2 4.5e-06 26.5 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 RJW64704.1 - 7.8e-29 99.4 4.2 1.9e-06 28.0 0.0 7.5 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 RJW64704.1 - 9.1e-24 83.2 2.4 0.00017 21.5 0.0 7.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 RJW64704.1 - 3.3e-21 74.8 0.4 0.0073 16.6 0.0 6.8 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 RJW64704.1 - 2.5e-16 59.0 0.3 0.00055 19.5 0.1 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 RJW64704.1 - 1.1e-15 56.9 0.7 0.0016 18.3 0.0 6.4 6 1 0 6 6 6 4 Kelch motif fn3 PF00041.21 RJW64704.1 - 5.6e-10 39.4 1.3 0.01 16.2 0.0 4.4 4 0 0 4 4 4 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW64704.1 - 0.034 14.7 0.6 0.72 10.5 0.0 3.1 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain DUF515 PF04415.12 RJW64704.1 - 7.7 4.8 8.1 12 4.1 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) 14-3-3 PF00244.20 RJW64706.1 - 0.007 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 14-3-3 protein Ldl_recept_a PF00057.18 RJW64708.1 - 0.00041 20.5 1.3 0.00094 19.4 0.3 2.0 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A TMEM154 PF15102.6 RJW64708.1 - 0.095 12.6 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family Baculo_11_kDa PF06143.11 RJW64708.1 - 0.45 10.1 2.9 0.86 9.2 2.9 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family zf-RING_2 PF13639.6 RJW64711.1 - 3e-13 49.9 6.3 3e-13 49.9 6.3 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RJW64711.1 - 6.4e-10 39.2 6.3 6.4e-10 39.2 6.3 2.5 3 0 0 3 3 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RJW64711.1 - 2.2e-08 33.8 6.3 2.2e-08 33.8 6.3 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW64711.1 - 5.7e-08 32.5 5.3 5.7e-08 32.5 5.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RJW64711.1 - 1.7e-07 30.8 1.6 1.7e-07 30.8 1.6 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RJW64711.1 - 2.1e-05 24.3 3.7 6.1e-05 22.8 3.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW64711.1 - 3.5e-05 23.7 4.1 0.00011 22.1 4.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RJW64711.1 - 7.8e-05 22.7 2.4 0.0003 20.8 2.4 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RJW64711.1 - 0.00028 20.8 1.6 0.00028 20.8 1.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger RINGv PF12906.7 RJW64711.1 - 0.02 15.0 6.5 0.048 13.8 6.5 1.7 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 RJW64711.1 - 0.081 12.6 3.5 0.19 11.3 3.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 RJW64711.1 - 0.12 12.2 2.3 0.37 10.7 2.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 RJW64711.1 - 0.13 12.1 5.3 0.34 10.8 5.3 1.8 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 RJW64711.1 - 0.16 12.2 3.4 0.5 10.6 3.4 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain MRP-S25 PF13741.6 RJW64712.1 - 0.075 12.6 0.3 0.15 11.6 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 Dynein_light PF01221.18 RJW64713.1 - 1.3e-08 35.0 0.0 2.9e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Dynein light chain type 1 EF-hand_6 PF13405.6 RJW64713.1 - 0.087 12.8 0.0 0.33 11.0 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain TrmB PF01978.19 RJW64713.1 - 0.14 12.1 0.1 6 6.8 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Gaa1 PF04114.14 RJW64714.1 - 6.6e-14 51.8 0.0 8.9e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Gaa1 PF04114.14 RJW64715.1 - 2.3e-44 152.3 0.0 3.1e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF4020 PF13212.6 RJW64715.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) fn3 PF00041.21 RJW64717.1 - 3.6e-40 136.2 1.7 1.9e-09 37.8 0.1 7.5 5 3 1 6 6 6 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW64717.1 - 1.4e-11 44.8 0.0 0.38 11.3 0.0 5.7 5 1 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain Neogenin_C PF06583.12 RJW64717.1 - 2.4e-08 34.2 0.3 2.4e-08 34.2 0.3 2.9 3 0 0 3 3 3 1 Neogenin C-terminus DUF2369 PF10179.9 RJW64717.1 - 6.9e-08 32.8 0.0 0.0053 17.1 0.0 4.7 5 0 0 5 5 5 2 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 RJW64717.1 - 0.15 12.4 0.0 11 6.4 0.0 2.9 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Chorion_2 PF03964.15 RJW64717.1 - 6.6 7.6 8.8 1.3 9.9 3.1 2.4 2 0 0 2 2 2 0 Chorion family 2 APP_E2 PF12925.7 RJW64718.1 - 3.7e-20 72.4 9.4 5.9e-20 71.8 9.4 1.3 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.16 RJW64718.1 - 9.9e-11 41.9 0.1 2.9e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding APP_amyloid PF10515.9 RJW64718.1 - 2.4e-05 24.8 0.0 8.6e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus ABC_tran_CTD PF16326.5 RJW64718.1 - 0.1 12.9 1.3 0.28 11.5 0.6 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain Suf PF05843.14 RJW64719.1 - 0.03 14.3 0.2 0.03 14.3 0.2 3.0 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) DUF3090 PF11290.8 RJW64719.1 - 0.06 13.2 1.8 0.17 11.6 1.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) TPR_11 PF13414.6 RJW64719.1 - 0.14 11.8 2.4 0.44 10.3 0.4 2.7 3 0 0 3 3 3 0 TPR repeat GDP_Man_Dehyd PF16363.5 RJW64720.1 - 5.8e-54 183.7 0.0 1.5e-53 182.3 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RJW64720.1 - 1.7e-52 178.3 0.0 2.2e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RJW64720.1 - 8.2e-10 38.3 0.0 1.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 RJW64720.1 - 2.7e-09 36.6 0.0 5.2e-05 22.5 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 RJW64720.1 - 8.8e-09 34.8 0.0 1.3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 RJW64720.1 - 6.9e-06 25.4 0.0 6.9e-05 22.1 0.0 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 RJW64720.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 RJW64720.1 - 0.069 13.0 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 KR domain NmrA PF05368.13 RJW64720.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family EB PF01683.18 RJW64720.1 - 1.4 9.3 5.3 2.6 8.4 5.3 1.4 1 0 0 1 1 1 0 EB module UPF1_Zn_bind PF09416.10 RJW64722.1 - 1.1e-69 233.2 7.3 1.6e-69 232.7 3.9 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 RJW64722.1 - 4.5e-61 206.0 0.0 9.8e-61 204.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RJW64722.1 - 1e-46 159.9 5.3 8.6e-28 97.8 0.9 2.6 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 RJW64722.1 - 3.3e-20 72.1 0.0 6.6e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 RJW64722.1 - 6.6e-13 48.8 0.2 4.7e-12 46.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RJW64722.1 - 1.1e-10 42.0 0.1 2.8e-10 40.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 RJW64722.1 - 1.7e-07 31.4 0.0 3.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 RJW64722.1 - 7.7e-06 25.4 0.2 0.00032 20.1 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 RJW64722.1 - 0.00021 21.1 0.1 0.7 9.6 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 RJW64722.1 - 0.0019 18.1 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 RJW64722.1 - 0.0028 17.3 0.2 0.0079 15.7 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 RJW64722.1 - 0.0088 15.8 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 RJW64722.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 RJW64722.1 - 0.025 14.9 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 RJW64722.1 - 0.039 13.1 0.0 8.7 5.4 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_5 PF07728.14 RJW64722.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 RJW64722.1 - 0.049 13.0 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 RJW64722.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 RJW64722.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 RJW64722.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_7 PF12775.7 RJW64722.1 - 0.2 11.2 0.0 0.48 9.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region HRM PF02793.22 RJW64725.1 - 8.1e-11 42.1 1.3 1.5e-10 41.2 1.3 1.4 1 0 0 1 1 1 1 Hormone receptor domain PAN_1 PF00024.26 RJW64726.1 - 0.0011 18.9 1.8 0.0025 17.7 1.8 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 RJW64726.1 - 1.6 8.6 8.8 0.43 10.4 3.3 2.3 2 0 0 2 2 2 0 PAN-like domain 7tm_1 PF00001.21 RJW64727.1 - 3.2e-20 72.6 13.7 3.2e-20 72.6 13.7 2.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW64727.1 - 2.3e-13 50.1 29.4 3.3e-08 33.2 18.6 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RJW64727.1 - 0.00072 19.3 15.1 0.00072 19.3 15.1 2.7 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpin PF00079.20 RJW64728.1 - 8.9e-68 229.3 0.0 1e-67 229.0 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Phage_tail_NK PF16532.5 RJW64728.1 - 0.081 12.5 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales Ndc1_Nup PF09531.10 RJW64730.1 - 2.6 6.6 10.0 3.3 6.3 10.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 RJW64730.1 - 9.6 3.2 14.1 11 2.9 14.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AMP-binding PF00501.28 RJW64731.1 - 4.7e-18 65.0 0.0 6.6e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DMAP_binding PF06464.11 RJW64731.1 - 1.7e-16 61.0 2.4 4.3e-15 56.5 0.0 2.9 3 0 0 3 3 3 1 DMAP1-binding Domain GvpG PF05120.12 RJW64731.1 - 0.0047 16.9 0.1 0.0098 15.9 0.1 1.4 1 0 0 1 1 1 1 Gas vesicle protein G TLD PF07534.16 RJW64732.1 - 3.1e-26 92.3 0.5 7.3e-26 91.0 0.1 1.8 2 0 0 2 2 2 1 TLD PDGF_N PF04692.13 RJW64732.1 - 0.0059 17.4 5.1 0.72 10.7 1.2 2.7 2 0 0 2 2 2 2 Platelet-derived growth factor, N terminal region DUF4469 PF14734.6 RJW64734.1 - 1.1e-06 28.8 9.0 45 4.3 0.0 7.5 1 1 5 6 6 6 6 Domain of unknown function (DUF4469) with IG-like fold 7tm_2 PF00002.24 RJW64735.1 - 1.2e-23 83.7 12.3 1.4e-23 83.5 12.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) IMPDH PF00478.25 RJW64736.1 - 0.089 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain TPH PF13868.6 RJW64737.1 - 7.1e-06 24.8 109.8 7.1e-06 24.8 109.8 2.5 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Ion_trans_N PF08412.10 RJW64739.1 - 2e-23 81.7 0.1 4.1e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 Ion transport protein N-terminal Ion_trans PF00520.31 RJW64739.1 - 3.9e-22 78.7 14.7 7.3e-22 77.8 14.7 1.4 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 RJW64739.1 - 1.6e-19 69.7 0.0 3.7e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RJW64739.1 - 0.0088 16.0 0.3 0.034 14.1 0.0 2.1 2 0 0 2 2 2 1 Ion channel LRR_adjacent PF08191.11 RJW64740.1 - 0.13 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 LRR adjacent TIP120 PF08623.10 RJW64741.1 - 3.3e-52 176.7 2.2 3.9e-50 169.9 0.5 4.2 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 RJW64741.1 - 1.8e-12 47.5 24.1 0.00019 21.7 0.1 9.3 9 2 0 9 9 8 3 HEAT repeats HEAT_EZ PF13513.6 RJW64741.1 - 3.2e-10 40.3 28.7 0.015 15.8 0.0 9.4 10 0 0 10 10 9 4 HEAT-like repeat HEAT PF02985.22 RJW64741.1 - 3.3e-09 36.2 29.6 0.33 11.3 0.0 11.1 12 0 0 12 12 11 4 HEAT repeat Vac14_Fab1_bd PF12755.7 RJW64741.1 - 4.7e-06 27.1 0.0 0.35 11.5 0.0 4.8 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 RJW64741.1 - 1.8e-05 25.0 0.0 0.0091 16.3 0.0 3.9 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain Ipi1_N PF12333.8 RJW64741.1 - 0.00062 20.3 3.9 0.0042 17.6 0.1 3.9 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.8 RJW64741.1 - 0.0012 18.5 0.4 1.9 8.0 0.1 3.1 2 1 0 2 2 2 2 CLASP N terminal NopRA1 PF16201.5 RJW64741.1 - 0.13 11.9 1.8 2 8.0 0.1 3.8 3 1 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 MOR2-PAG1_N PF14222.6 RJW64741.1 - 0.14 11.1 5.6 20 4.0 0.2 3.6 3 0 0 3 3 3 0 Cell morphogenesis N-terminal HEAT_PBS PF03130.16 RJW64741.1 - 1.3 9.9 11.6 16 6.6 0.1 6.3 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat Adaptin_N PF01602.20 RJW64741.1 - 4.1 5.8 12.0 0.11 11.1 1.3 3.8 4 1 0 4 4 4 0 Adaptin N terminal region DUF4804 PF16062.5 RJW64742.1 - 0.098 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) zf-C2H2_4 PF13894.6 RJW64744.1 - 1.8e-17 62.5 38.6 0.00017 22.1 0.4 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW64744.1 - 7.5e-16 57.6 38.8 1e-05 25.7 0.6 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW64744.1 - 1.3e-08 34.8 32.3 0.016 15.7 1.6 7.3 6 2 0 6 6 6 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 RJW64744.1 - 0.0003 20.5 0.2 0.0003 20.5 0.2 4.8 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-met PF12874.7 RJW64744.1 - 0.00057 20.2 26.9 0.13 12.7 2.9 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RJW64744.1 - 0.0011 18.9 33.5 0.1 12.6 2.7 5.7 5 1 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.12 RJW64744.1 - 0.0011 19.2 30.2 0.0025 18.1 9.4 4.3 3 2 2 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 RJW64744.1 - 0.012 16.4 21.4 0.057 14.2 0.9 3.3 2 1 1 3 3 3 0 zinc-ribbon family zf-H2C2_5 PF13909.6 RJW64744.1 - 0.06 13.1 24.0 0.17 11.7 1.0 5.8 4 1 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RJW64744.1 - 0.11 12.9 0.5 0.11 12.9 0.5 5.1 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 RJW64744.1 - 0.15 12.2 14.8 0.27 11.4 1.1 4.0 3 2 1 4 4 4 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 RJW64744.1 - 0.16 12.6 16.2 0.1 13.2 11.0 2.8 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 RJW64744.1 - 0.17 11.5 19.2 0.22 11.1 0.5 4.8 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger ROS_MUCR PF05443.11 RJW64744.1 - 0.2 11.7 5.0 2.7 8.1 0.2 2.7 2 1 1 3 3 3 0 ROS/MUCR transcriptional regulator protein zf-C2H2_2 PF12756.7 RJW64744.1 - 0.2 12.0 30.0 1.9 8.9 2.2 5.0 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 RJW64744.1 - 0.3 10.7 21.4 1 9.1 0.2 5.4 4 2 2 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_C2H2_13 PF18508.1 RJW64744.1 - 0.32 10.6 4.5 5.8 6.6 0.2 2.9 1 1 1 2 2 2 0 Zinc finger domain zf-C2H2_9 PF16293.5 RJW64744.1 - 0.49 10.3 18.5 2.7 7.9 1.2 5.3 4 1 2 6 6 6 0 C2H2 type zinc-finger (1 copy) FOXP-CC PF16159.5 RJW64744.1 - 0.54 10.9 20.5 2.3 8.9 0.5 4.9 1 1 4 5 5 5 0 FOXP coiled-coil domain CpXC PF14353.6 RJW64744.1 - 0.82 9.7 20.4 16 5.6 9.8 4.1 1 1 2 3 3 3 0 CpXC protein ADK_lid PF05191.14 RJW64744.1 - 3.7 7.6 10.7 5.8 7.0 0.1 4.0 2 2 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_12 PF18658.1 RJW64744.1 - 3.7 7.2 19.9 0.65 9.6 0.4 4.5 3 2 2 5 5 5 0 Zinc-finger C2H2-type Mut7-C PF01927.16 RJW64744.1 - 5 7.2 20.8 0.56 10.3 1.2 3.4 1 1 2 3 3 3 0 Mut7-C RNAse domain HLH PF00010.26 RJW64745.1 - 9.8e-14 51.1 0.1 2.1e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain hEGF PF12661.7 RJW64746.1 - 0.00018 22.0 0.9 0.34 11.6 0.1 3.5 2 0 0 2 2 2 2 Human growth factor-like EGF cEGF PF12662.7 RJW64746.1 - 0.0002 21.2 7.9 0.0067 16.3 0.2 3.1 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.7 RJW64746.1 - 0.039 14.1 5.9 0.96 9.7 0.1 3.3 2 1 1 3 3 3 0 EGF domain Amdo_NSP PF12475.8 RJW64746.1 - 0.072 13.2 3.0 0.68 10.1 0.2 3.2 3 0 0 3 3 3 0 Amdovirus non-structural protein Laminin_EGF PF00053.24 RJW64746.1 - 0.083 13.0 8.1 0.23 11.6 1.3 3.5 2 0 0 2 2 2 0 Laminin EGF domain EGF_CA PF07645.15 RJW64746.1 - 0.11 12.7 9.5 0.067 13.4 1.1 3.3 2 0 0 2 2 2 0 Calcium-binding EGF domain EGF PF00008.27 RJW64746.1 - 0.39 11.1 9.4 0.7 10.3 0.1 3.6 3 0 0 3 3 3 0 EGF-like domain FXa_inhibition PF14670.6 RJW64746.1 - 4.6 7.6 19.1 0.18 12.1 1.0 4.0 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site HLH PF00010.26 RJW64747.1 - 6e-15 55.0 2.7 1.1e-14 54.1 2.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 RJW64747.1 - 1.5e-08 35.9 3.7 1.5e-08 35.9 3.7 2.3 2 2 1 3 3 3 1 Neuronal helix-loop-helix transcription factor TSP_1 PF00090.19 RJW64748.1 - 7.8e-05 22.8 7.9 7.8e-05 22.8 7.9 2.6 2 0 0 2 2 2 1 Thrombospondin type 1 domain EGF PF00008.27 RJW64748.1 - 0.0019 18.5 1.7 0.0019 18.5 1.7 6.0 5 1 0 5 5 5 2 EGF-like domain FXa_inhibition PF14670.6 RJW64748.1 - 0.003 17.8 1.0 0.003 17.8 1.0 5.6 5 0 0 5 5 5 2 Coagulation Factor Xa inhibitory site RANK_CRD_2 PF18278.1 RJW64748.1 - 0.024 14.8 0.7 0.024 14.8 0.7 3.5 3 0 0 3 3 3 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 EGF_2 PF07974.13 RJW64748.1 - 0.033 14.5 6.3 0.033 14.5 6.3 6.2 7 0 0 7 7 7 0 EGF-like domain hEGF PF12661.7 RJW64748.1 - 0.068 13.8 1.4 0.068 13.8 1.4 5.5 5 0 0 5 5 5 0 Human growth factor-like EGF RT_RNaseH_2 PF17919.1 RJW64750.1 - 0.0009 19.2 0.0 0.0024 17.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Caprin-1_C PF12287.8 RJW64750.1 - 0.047 13.8 0.8 0.049 13.8 0.8 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term MFS_1 PF07690.16 RJW64751.1 - 4.2e-20 72.0 42.8 4.6e-14 52.1 12.7 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily CENP-B_dimeris PF09026.10 RJW64751.1 - 3.7 8.0 15.1 6.1 7.3 6.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Aldo_ket_red PF00248.21 RJW64752.1 - 8e-29 100.7 0.0 6.8e-27 94.4 0.0 2.7 1 1 0 1 1 1 1 Aldo/keto reductase family Oxysterol_BP PF01237.18 RJW64753.1 - 1.6e-121 405.7 0.0 8.6e-121 403.3 0.0 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein Bcl-2 PF00452.19 RJW64754.1 - 1.9e-10 41.3 8.4 6.9e-09 36.3 0.8 3.0 2 1 0 2 2 2 2 Apoptosis regulator proteins, Bcl-2 family Bcl-2_3 PF15286.6 RJW64754.1 - 0.075 13.7 0.1 0.3 11.7 0.1 1.9 1 1 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like CxC5 PF18718.1 RJW64755.1 - 0.037 14.1 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases BAH PF01426.18 RJW64756.1 - 1.5e-13 50.7 1.1 4.4e-12 45.9 1.1 2.3 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.24 RJW64756.1 - 0.027 15.2 0.0 0.18 12.6 0.0 2.5 1 1 0 1 1 1 0 ELM2 domain AAA PF00004.29 RJW64759.1 - 2.5e-35 121.8 0.0 6e-35 120.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW64759.1 - 3.4e-10 39.6 0.0 9.5e-10 38.1 0.0 1.8 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 RJW64759.1 - 8.1e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain LisH PF08513.11 RJW64759.1 - 0.00021 21.1 0.2 0.00066 19.5 0.2 1.9 1 0 0 1 1 1 1 LisH AAA_16 PF13191.6 RJW64759.1 - 0.0013 19.2 0.1 0.0032 17.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 RJW64759.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 RJW64759.1 - 0.0033 17.4 0.0 0.0088 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RJW64759.1 - 0.0039 17.5 0.1 0.014 15.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RJW64759.1 - 0.0041 16.9 0.0 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 RJW64759.1 - 0.0044 16.8 0.0 0.0095 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RJW64759.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 RJW64759.1 - 0.014 15.8 0.0 0.042 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 RJW64759.1 - 0.023 14.8 0.0 0.066 13.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 RJW64759.1 - 0.028 14.5 0.0 0.098 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RJW64759.1 - 0.031 14.8 0.3 0.13 12.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RJW64759.1 - 0.033 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 RJW64759.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 RJW64759.1 - 0.12 12.0 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RJW64759.1 - 0.14 11.6 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 RJW64759.1 - 0.14 11.8 0.1 2.1 8.0 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 RJW64759.1 - 0.15 11.2 0.0 0.36 9.9 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sedlin_N PF04628.13 RJW64761.1 - 5e-06 26.7 0.3 0.0034 17.5 0.1 2.0 1 1 1 2 2 2 2 Sedlin, N-terminal conserved region fn3 PF00041.21 RJW64762.1 - 1.3e-09 38.3 5.9 0.0003 21.1 0.0 5.0 5 0 0 5 5 5 2 Fibronectin type III domain Interfer-bind PF09294.10 RJW64762.1 - 0.0037 17.6 0.0 3.2 8.1 0.0 2.6 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 RJW64762.1 - 0.028 15.0 3.8 3.3 8.4 0.6 3.4 2 1 1 3 3 3 0 Purple acid Phosphatase, N-terminal domain RVT_1 PF00078.27 RJW64763.1 - 0.0046 16.5 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1387 PF07139.11 RJW64763.1 - 0.089 12.5 6.6 0.52 10.0 8.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Pkinase PF00069.25 RJW64764.1 - 5.6e-64 216.0 0.0 7.4e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 RJW64764.1 - 1.8e-31 108.0 0.0 5.3e-18 64.9 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RJW64764.1 - 8.1e-31 107.2 0.0 1.4e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW64764.1 - 3.1e-05 23.4 0.0 6.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RJW64764.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RVT_1 PF00078.27 RJW64765.1 - 2e-39 135.4 0.0 4.6e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.25 RJW64765.1 - 0.0057 16.1 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF4500 PF14937.6 RJW64767.1 - 1.9e-07 31.0 0.3 2.7e-07 30.5 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4500) RNase_PH PF01138.21 RJW64768.1 - 1.1e-27 97.1 0.0 1.7e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_C12 PF01088.21 RJW64772.1 - 1e-48 165.9 0.0 1.2e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 LRR_9 PF14580.6 RJW64775.1 - 8e-06 25.5 0.3 1.4e-05 24.6 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RJW64775.1 - 0.00025 21.4 6.0 0.0016 18.8 2.5 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW64775.1 - 0.0091 15.7 1.8 0.025 14.4 1.8 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 RJW64775.1 - 0.54 10.4 3.2 3.3 8.0 0.2 2.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 RJW64775.1 - 0.78 10.5 3.1 71 4.6 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat Pkinase PF00069.25 RJW64777.1 - 2e-07 30.6 0.0 1.3e-05 24.7 0.0 2.6 1 1 2 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64777.1 - 0.00082 18.7 0.0 0.15 11.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Myc_N PF01056.18 RJW64777.1 - 0.33 10.8 20.7 0.78 9.6 6.5 2.6 2 0 0 2 2 2 0 Myc amino-terminal region Tim54 PF11711.8 RJW64777.1 - 3.7 6.3 13.5 0.36 9.6 0.8 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.6 RJW64777.1 - 3.9 7.1 20.9 2.1 8.0 3.4 2.6 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.13 RJW64777.1 - 4.1 7.2 27.1 19 5.0 18.8 3.1 3 0 0 3 3 3 0 Sigma-70, non-essential region FERM_C PF09380.10 RJW64778.1 - 2.2e-17 63.2 0.6 5.3e-13 49.2 0.2 2.4 2 0 0 2 2 2 2 FERM C-terminal PH-like domain FERM_M PF00373.18 RJW64778.1 - 5.9e-08 33.1 0.2 1.1e-05 25.8 0.0 2.6 2 0 0 2 2 2 2 FERM central domain PTEN_C2 PF10409.9 RJW64779.1 - 8.1e-10 38.6 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PTPlike_phytase PF14566.6 RJW64779.1 - 2.5e-05 24.4 0.0 6.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RJW64779.1 - 0.0014 18.6 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RJW64779.1 - 0.032 13.8 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 RJW64779.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PCI PF01399.27 RJW64782.1 - 2.1e-12 47.5 0.0 4.4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 RJW64782.1 - 9.6e-09 35.3 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain RPN7 PF10602.9 RJW64782.1 - 0.00067 19.4 0.5 0.001 18.8 0.5 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 RJW64782.1 - 0.069 13.3 0.1 0.3 11.3 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 RJW64782.1 - 0.09 13.0 3.0 0.21 11.9 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RJW64782.1 - 0.66 10.9 0.2 0.66 10.9 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 RJW64782.1 - 0.78 10.3 4.7 1.1 9.8 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat RVT_1 PF00078.27 RJW64783.1 - 1.6e-34 119.3 0.0 6.6e-34 117.4 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4693 PF15764.5 RJW64783.1 - 0.042 13.4 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4693) Peptidase_M14 PF00246.24 RJW64784.1 - 1.3e-16 61.2 0.0 4.8e-16 59.4 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 RJW64784.1 - 1.4e-10 41.4 1.5 1.4e-10 41.4 1.5 2.2 2 1 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 RJW64784.1 - 0.0019 17.3 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF3585 PF12130.8 RJW64785.1 - 2.4e-21 76.3 11.4 4.5e-21 75.4 11.4 1.4 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain DASH_Duo1 PF08651.10 RJW64785.1 - 0.0013 18.5 1.1 0.0026 17.5 1.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 MCM6_C PF18263.1 RJW64785.1 - 0.23 11.7 2.3 0.47 10.7 2.3 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Prefoldin_2 PF01920.20 RJW64785.1 - 0.71 9.9 6.7 1.6 8.7 6.7 1.6 1 1 0 1 1 1 0 Prefoldin subunit LMBR1 PF04791.16 RJW64785.1 - 0.76 8.6 3.7 1.2 8.0 3.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5129 PF17173.4 RJW64785.1 - 1 8.4 3.9 0.27 10.3 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5129) Occludin_ELL PF07303.13 RJW64785.1 - 4.8 8.0 8.2 48 4.8 6.4 2.4 1 1 1 2 2 2 0 Occludin homology domain VHL PF01847.16 RJW64787.1 - 0.0042 17.0 0.0 0.0078 16.1 0.0 1.4 2 0 0 2 2 2 1 VHL beta domain DUF2207 PF09972.9 RJW64789.1 - 0.13 11.0 0.1 0.23 10.2 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LEF-8 PF04941.12 RJW64790.1 - 0.054 11.8 0.1 0.063 11.5 0.1 1.1 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) HTH_AraC PF00165.23 RJW64790.1 - 0.17 12.1 1.5 0.31 11.2 0.4 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF4817 PF16087.5 RJW64792.1 - 2e-14 53.1 0.1 1.5e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) MerR PF00376.23 RJW64792.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein GIY-YIG PF01541.24 RJW64793.1 - 0.021 15.1 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain 7TM_GPCR_Srw PF10324.9 RJW64794.1 - 0.00033 20.0 26.8 0.0024 17.2 18.5 3.4 2 2 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RJW64794.1 - 0.0044 16.7 6.4 0.0044 16.7 6.4 3.3 4 0 0 4 4 4 2 Serpentine type 7TM GPCR chemoreceptor Srx DHHA2 PF02833.14 RJW64795.1 - 6.7e-14 52.3 0.0 1.1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 RJW64795.1 - 0.041 14.1 1.1 0.15 12.3 0.9 2.0 2 1 0 2 2 2 0 DHH family Peptidase_M1 PF01433.20 RJW64797.1 - 7.9e-85 283.9 1.7 1.2e-84 283.2 1.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RJW64797.1 - 2.2e-37 129.1 0.0 3.4e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 RJW64797.1 - 0.038 13.3 0.2 0.079 12.3 0.2 1.4 1 0 0 1 1 1 0 Putative aminopeptidase Zincin_1 PF06262.11 RJW64797.1 - 0.13 12.3 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Zincin-like metallopeptidase Enterotoxin_ST PF02048.16 RJW64798.1 - 0.15 12.6 0.1 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Heat-stable enterotoxin ST NFRKB_winged PF14465.6 RJW64801.1 - 0.0019 18.4 0.2 0.016 15.4 0.1 2.6 2 1 0 2 2 2 1 NFRKB Winged Helix-like zf-CCCH PF00642.24 RJW64802.1 - 6e-12 45.1 15.7 7.3e-08 32.1 2.0 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RJW64802.1 - 2.7e-06 27.0 24.1 0.0004 20.1 4.5 3.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RJW64802.1 - 8.5e-06 26.1 15.5 0.012 16.0 3.6 2.8 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 RJW64802.1 - 0.00016 21.6 19.7 0.03 14.4 8.1 2.9 2 1 0 2 2 2 2 Zinc finger domain PAC4 PF16093.5 RJW64802.1 - 0.11 12.6 0.4 0.35 11.1 0.4 1.8 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 SecD-TM1 PF13721.6 RJW64802.1 - 0.12 12.9 0.2 0.27 11.7 0.2 1.5 1 0 0 1 1 1 0 SecD export protein N-terminal TM region Torus PF16131.5 RJW64802.1 - 2.4 8.9 9.9 1.2 9.9 1.2 2.6 1 1 1 2 2 2 0 Torus domain RVT_1 PF00078.27 RJW64806.1 - 3.9e-29 101.7 0.0 6.9e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_9 PF14580.6 RJW64806.1 - 9.4e-14 51.3 11.4 3.7e-13 49.4 2.8 2.9 1 1 2 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 RJW64806.1 - 1.4e-12 47.6 25.5 1e-05 25.8 2.3 5.4 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW64806.1 - 5.8e-08 32.4 25.0 2.4e-05 24.0 1.6 5.0 3 1 1 4 4 4 3 Leucine rich repeat dNK PF01712.19 RJW64807.1 - 2.4e-35 122.2 0.0 3.4e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 RJW64807.1 - 0.0018 18.5 0.1 0.0082 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RJW64807.1 - 0.2 12.2 0.0 0.41 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ig PF00047.25 RJW64808.1 - 0.095 12.9 0.6 8.5 6.6 0.0 4.1 5 0 0 5 5 5 0 Immunoglobulin domain Pkinase PF00069.25 RJW64809.1 - 3.2e-69 233.2 0.0 4e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64809.1 - 1.5e-33 116.2 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW64809.1 - 8e-08 31.9 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW64809.1 - 0.0061 15.5 0.1 0.0094 14.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain ubiquitin PF00240.23 RJW64810.1 - 2.8e-13 49.4 0.0 5.7e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 RJW64810.1 - 1.6e-06 28.1 11.1 4.1e-06 26.8 11.1 1.7 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 RJW64810.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RJW64810.1 - 0.027 14.4 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Histone PF00125.24 RJW64811.1 - 3.2e-18 66.4 0.0 5.4e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 RJW64811.1 - 6.7e-12 44.9 0.6 1.5e-11 43.8 0.6 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 RJW64811.1 - 0.031 14.5 0.1 0.089 13.1 0.0 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RVT_1 PF00078.27 RJW64812.1 - 2.4e-33 115.5 0.0 5.1e-33 114.5 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 RJW64813.1 - 3.8e-47 160.9 57.2 1.2e-33 116.6 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 RJW64813.1 - 0.015 13.6 16.4 0.0074 14.6 11.5 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Laminin_G_2 PF02210.24 RJW64814.1 - 6.9e-36 123.6 8.6 1.3e-07 32.2 0.1 7.1 5 2 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 RJW64814.1 - 1.3e-21 77.2 0.1 0.00027 21.2 0.0 6.3 6 0 0 6 6 6 5 Laminin G domain Laminin_G_3 PF13385.6 RJW64814.1 - 6.9e-11 42.5 0.5 0.017 15.2 0.0 4.3 4 1 0 4 4 4 3 Concanavalin A-like lectin/glucanases superfamily PX PF00787.24 RJW64815.1 - 1.9e-19 69.7 0.3 4.5e-19 68.5 0.3 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 RJW64815.1 - 1.7e-15 57.2 10.9 5e-13 49.1 10.9 2.4 1 1 0 1 1 1 1 Vps5 C terminal like Acyl-CoA_dh_2 PF08028.11 RJW64815.1 - 1.1 9.6 6.6 0.17 12.2 2.2 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain HEAT_EZ PF13513.6 RJW64817.1 - 0.00096 19.6 1.3 0.17 12.4 0.1 4.3 3 0 0 3 3 3 1 HEAT-like repeat Gly-rich_Ago1 PF12764.7 RJW64817.1 - 0.015 16.1 0.9 0.059 14.1 0.9 2.0 1 0 0 1 1 1 0 Glycine-rich region of argonaut HEAT PF02985.22 RJW64817.1 - 0.018 15.3 0.0 0.018 15.3 0.0 6.1 6 0 0 6 6 6 0 HEAT repeat HEAT_2 PF13646.6 RJW64817.1 - 0.029 14.8 0.5 5 7.6 0.0 4.2 4 0 0 4 4 4 0 HEAT repeats Med21 PF11221.8 RJW64818.1 - 4.8e-18 65.8 0.0 4.8e-18 65.8 0.0 2.3 3 0 0 3 3 3 1 Subunit 21 of Mediator complex CHD5 PF04420.14 RJW64818.1 - 2.5e-07 30.7 0.2 1.9e-06 27.8 0.0 2.3 2 1 1 3 3 3 1 CHD5-like protein PA28_beta PF02252.18 RJW64819.1 - 7.8e-35 119.7 0.0 1.3e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 RJW64819.1 - 4.1e-06 26.7 0.0 1.4e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Metallophos PF00149.28 RJW64820.1 - 8.2e-37 127.7 0.1 1.1e-36 127.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RJW64820.1 - 1.3e-11 44.7 2.4 2.6e-11 43.8 1.7 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Homeodomain PF00046.29 RJW64822.1 - 2.8e-17 62.3 0.6 1.8e-16 59.7 1.0 2.0 2 0 0 2 2 2 1 Homeodomain LIM PF00412.22 RJW64822.1 - 1e-08 35.3 5.6 1.9e-08 34.4 5.6 1.5 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 RJW64822.1 - 0.0019 18.0 0.1 0.0044 16.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-RING_5 PF14634.6 RJW64822.1 - 3 7.9 8.7 8.6 6.4 8.7 1.9 1 1 0 1 1 1 0 zinc-RING finger domain DUF3421 PF11901.8 RJW64823.1 - 7.9e-42 141.9 6.5 1.1e-39 134.9 3.1 2.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) SAM_3 PF18016.1 RJW64824.1 - 0.018 14.8 1.0 2.4 8.0 0.1 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Prok-RING_1 PF14446.6 RJW64824.1 - 0.1 12.6 1.8 8.8 6.3 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Dicty_REP PF05086.12 RJW64824.1 - 1.1 7.2 10.4 1.4 6.8 10.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Jnk-SapK_ap_N PF09744.9 RJW64825.1 - 9.2e-27 94.2 5.0 9.2e-27 94.2 5.0 3.1 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 RILP PF11461.8 RJW64825.1 - 6.9e-08 32.6 2.7 6.9e-08 32.6 2.7 2.2 2 0 0 2 2 2 1 Rab interacting lysosomal protein ATG16 PF08614.11 RJW64825.1 - 0.00084 19.6 22.7 0.0053 17.0 8.1 3.9 3 1 1 4 4 4 3 Autophagy protein 16 (ATG16) DUF3142 PF11340.8 RJW64825.1 - 0.064 13.1 0.7 0.12 12.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) HEPN_RES_NTD1 PF18870.1 RJW64825.1 - 0.11 12.7 2.0 0.19 11.9 2.0 1.4 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 JAKMIP_CC3 PF16034.5 RJW64825.1 - 0.12 12.3 8.3 0.42 10.5 8.3 1.8 1 0 0 1 1 1 0 JAKMIP CC3 domain Herpes_UL14 PF03580.14 RJW64826.1 - 0.025 14.8 4.6 0.033 14.4 4.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL14-like protein SlyX PF04102.12 RJW64826.1 - 0.53 10.9 5.0 0.4 11.3 3.0 1.8 2 1 0 2 2 2 0 SlyX CRAL_TRIO PF00650.20 RJW64827.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 CRAL/TRIO domain Sulfotransfer_2 PF03567.14 RJW64828.1 - 2.3e-32 112.9 0.8 4.3e-32 112.0 0.2 1.8 2 1 0 2 2 2 1 Sulfotransferase family CSG2 PF16965.5 RJW64830.1 - 0.13 11.1 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Peptidase_M16 PF00675.20 RJW64831.1 - 4.6e-17 62.4 0.0 1.1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RJW64831.1 - 1.4e-13 51.3 0.0 4.4e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain COesterase PF00135.28 RJW64832.1 - 2.8e-90 303.7 0.0 3.9e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RJW64832.1 - 0.0021 18.0 0.0 0.044 13.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold SNF2_N PF00176.23 RJW64833.1 - 1.2e-64 218.2 0.0 2.1e-64 217.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3535 PF12054.8 RJW64833.1 - 6.4e-33 114.6 0.1 8e-30 104.4 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3535) Helicase_C PF00271.31 RJW64833.1 - 4.5e-16 59.2 0.0 1.2e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW64833.1 - 0.00049 20.1 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HEAT PF02985.22 RJW64833.1 - 0.97 9.9 9.9 3.3 8.2 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat DUF4487 PF14868.6 RJW64834.1 - 1.4e-25 90.2 0.5 2.3e-25 89.5 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4487) RB_A PF01858.17 RJW64835.1 - 8.1e-64 215.1 0.4 2.7e-63 213.4 0.4 2.0 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 RJW64835.1 - 8.8e-43 145.5 3.9 1.5e-40 138.3 0.7 2.5 2 0 0 2 2 2 2 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 RJW64835.1 - 1.2e-33 115.6 0.6 3.8e-33 114.0 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) DNA_pol3_delta PF06144.13 RJW64835.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Sec2p PF06428.11 RJW64836.1 - 2.6e-07 30.5 3.0 2.6e-07 30.5 3.0 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Cut12 PF11500.8 RJW64836.1 - 0.37 10.7 3.5 0.84 9.6 3.5 1.5 1 0 0 1 1 1 0 Spindle pole body formation-associated protein NEMO PF11577.8 RJW64836.1 - 0.77 9.8 5.8 0.83 9.7 1.5 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO bZIP_1 PF00170.21 RJW64836.1 - 9.9 6.3 16.5 12 6.1 1.8 4.0 4 0 0 4 4 4 0 bZIP transcription factor Acetyltransf_1 PF00583.25 RJW64837.1 - 1.1e-09 38.5 0.1 1.8e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RJW64837.1 - 3.6e-06 27.3 0.0 0.0065 16.9 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RJW64837.1 - 0.0074 16.4 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RJW64837.1 - 0.056 13.4 0.0 8.7 6.3 0.0 2.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RJW64837.1 - 0.13 12.4 0.0 9 6.4 0.0 2.6 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Bcl-2 PF00452.19 RJW64838.1 - 2.6e-19 69.8 0.0 4.7e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family CUB PF00431.20 RJW64839.1 - 4.3e-21 75.3 0.0 5.5e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 CUB domain GMP_synt_C PF00958.22 RJW64842.1 - 1e-19 70.3 0.0 4.7e-11 42.6 0.0 3.7 4 2 0 4 4 4 2 GMP synthase C terminal domain NAD_synthase PF02540.17 RJW64842.1 - 1.2e-09 37.7 0.1 2e-05 23.8 0.1 2.3 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 RJW64842.1 - 7e-06 25.7 0.0 0.00019 21.0 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 RJW64842.1 - 1.2e-05 25.0 0.1 0.0008 19.0 0.1 2.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 RJW64842.1 - 2.9e-05 23.0 0.2 0.00044 19.2 0.1 2.1 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 RJW64842.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 RJW64842.1 - 0.0014 18.4 0.1 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 PP-loop family ECH_1 PF00378.20 RJW64843.1 - 1.5e-49 168.6 0.1 1.8e-49 168.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RJW64843.1 - 1.7e-25 90.2 1.5 3.1e-24 86.1 0.3 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Pterin_4a PF01329.19 RJW64845.1 - 7.8e-30 102.9 0.1 8.6e-30 102.8 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase RasGEF PF00617.19 RJW64846.1 - 5.7e-17 62.5 0.1 5.7e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 RasGEF domain RasGEF_N PF00618.20 RJW64846.1 - 1.7e-05 25.0 0.0 0.00019 21.6 0.0 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif 7tm_1 PF00001.21 RJW64847.1 - 1.6e-09 37.5 20.1 2.7e-09 36.7 20.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RRM_1 PF00076.22 RJW64848.1 - 7.2e-13 48.2 0.0 1.6e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 RJW64848.1 - 2.5e-07 31.2 0.1 2.5e-07 31.2 0.1 2.7 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 QVR PF17064.5 RJW64849.1 - 4.7e-07 30.0 6.4 7.1e-07 29.4 6.4 1.3 1 0 0 1 1 1 1 Sleepless protein CxC2 PF18803.1 RJW64849.1 - 0.017 15.3 0.1 0.03 14.5 0.1 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases DEAD PF00270.29 RJW64850.1 - 2.2e-44 151.3 1.4 4e-44 150.5 0.2 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW64850.1 - 3.1e-25 88.7 0.1 2.2e-24 85.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW64850.1 - 5.2e-07 29.8 0.0 1.4e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 RJW64850.1 - 7.2e-06 26.1 0.0 4.3e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) UvrD-helicase PF00580.21 RJW64850.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ERCC3_RAD25_C PF16203.5 RJW64850.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 RJW64850.1 - 0.031 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 RJW64850.1 - 0.088 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Stathmin PF00836.19 RJW64851.1 - 0.00057 19.9 14.2 0.00057 19.9 14.2 2.1 1 1 1 2 2 2 1 Stathmin family DUF3584 PF12128.8 RJW64851.1 - 0.12 9.8 16.4 0.14 9.6 16.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IF-2B PF01008.17 RJW64851.1 - 0.16 11.1 6.0 0.14 11.4 5.1 1.3 1 1 0 1 1 1 0 Initiation factor 2 subunit family Prominin PF05478.11 RJW64851.1 - 0.26 9.2 8.5 0.3 9.0 8.5 1.0 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 RJW64851.1 - 0.69 9.4 12.1 0.82 9.2 12.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MbeB_N PF04837.12 RJW64851.1 - 0.97 9.8 8.9 0.39 11.1 3.5 2.5 1 1 1 2 2 2 0 MbeB-like, N-term conserved region Mit_KHE1 PF10173.9 RJW64851.1 - 0.99 9.5 6.6 1.3 9.1 6.6 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related GNT-I PF03071.15 RJW64851.1 - 3.7 6.2 8.5 4.6 5.9 8.5 1.0 1 0 0 1 1 1 0 GNT-I family ARD PF03079.14 RJW64851.1 - 6.1 7.0 11.0 5.1 7.3 7.9 1.9 1 1 1 2 2 2 0 ARD/ARD' family TetR_C_23 PF17931.1 RJW64851.1 - 7.1 6.8 9.2 17 5.6 4.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ACCA PF03255.14 RJW64851.1 - 9.5 6.1 11.3 3.7 7.4 7.6 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Cadherin PF00028.17 RJW64852.1 - 3.2e-56 187.7 0.2 9.9e-19 67.6 0.1 6.9 6 1 0 6 6 6 6 Cadherin domain Cadherin_3 PF16184.5 RJW64852.1 - 1.2e-07 31.7 1.2 2.2 8.3 0.1 6.2 7 0 0 7 7 7 4 Cadherin-like Ndr PF03096.14 RJW64853.1 - 5e-60 202.6 0.0 6.9e-40 136.5 0.0 2.1 1 1 1 2 2 2 2 Ndr family Abhydrolase_1 PF00561.20 RJW64853.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold NIF PF03031.18 RJW64855.1 - 1.1e-09 38.3 0.2 6.1e-09 35.8 0.2 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 RJW64855.1 - 0.0021 17.6 0.1 0.0033 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) UPF0561 PF10573.9 RJW64855.1 - 0.024 14.8 0.3 0.054 13.6 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 zf-C4 PF00105.18 RJW64856.1 - 2.9e-29 101.3 19.5 6.9e-29 100.1 19.5 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW64856.1 - 6.7e-29 101.0 0.9 1.2e-14 54.4 0.2 2.4 1 1 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor Headcase PF16002.5 RJW64857.1 - 2.8e-51 173.8 9.2 6.4e-25 87.8 0.0 3.5 3 0 0 3 3 3 3 Headcase protein HECA PF15353.6 RJW64857.1 - 0.0017 18.6 1.7 0.0017 18.6 1.7 2.1 2 0 0 2 2 2 1 Headcase protein family homologue SOUL PF04832.12 RJW64858.1 - 1.2e-25 90.7 0.0 2.4e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 SOUL heme-binding protein DMAP1 PF05499.12 RJW64859.1 - 1.5e-48 164.8 0.4 8.6e-32 110.3 0.0 2.6 2 0 0 2 2 2 2 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 RJW64859.1 - 7.3e-27 93.4 0.2 1.4e-26 92.4 0.2 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 FAM199X PF15814.5 RJW64859.1 - 0.34 9.9 9.0 0.99 8.4 9.0 1.7 1 0 0 1 1 1 0 Protein family FAM199X IRS PF02174.17 RJW64860.1 - 1.2e-08 34.7 0.0 3.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Macin PF14865.6 RJW64861.1 - 0.077 13.5 2.2 7.1 7.3 0.3 2.2 2 0 0 2 2 2 0 Macin 7tm_1 PF00001.21 RJW64863.1 - 8.2e-10 38.4 18.7 1.1e-09 38.0 18.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 RJW64863.1 - 0.00023 20.8 7.9 0.00023 20.8 7.9 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.9 RJW64863.1 - 0.008 15.8 19.4 0.016 14.8 19.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SOUL PF04832.12 RJW64864.1 - 6.7e-43 146.8 0.6 7.8e-43 146.6 0.6 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein BLOC1_2 PF10046.9 RJW64866.1 - 1e-19 70.6 1.4 1.3e-19 70.3 1.4 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRPM_tetra PF16519.5 RJW64866.1 - 0.0012 18.9 0.2 0.0032 17.5 0.1 1.8 2 0 0 2 2 2 1 Tetramerisation domain of TRPM DUF4726 PF15855.5 RJW64866.1 - 0.0098 16.1 0.7 0.024 14.8 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4726) Spectrin PF00435.21 RJW64866.1 - 0.016 15.7 0.3 0.043 14.3 0.2 1.7 1 1 0 1 1 1 0 Spectrin repeat Lebercilin PF15619.6 RJW64866.1 - 0.028 14.1 1.9 0.037 13.7 1.9 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Phage_GPO PF05929.11 RJW64866.1 - 0.033 13.8 0.4 0.035 13.7 0.4 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Tropomyosin_1 PF12718.7 RJW64866.1 - 0.043 14.0 1.0 0.053 13.7 1.0 1.1 1 0 0 1 1 1 0 Tropomyosin like Baculo_PEP_C PF04513.12 RJW64866.1 - 0.11 12.6 0.6 0.16 12.0 0.4 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMCCDC2 PF15844.5 RJW64866.1 - 0.17 11.8 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 UPF0184 PF03670.13 RJW64866.1 - 0.19 12.2 1.5 1.1 9.7 0.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) WXG100 PF06013.12 RJW64866.1 - 0.31 11.3 2.4 3.7 7.8 0.0 2.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG PDZ PF00595.24 RJW64867.1 - 1.3e-13 51.0 0.0 2.5e-13 50.2 0.0 1.5 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 RJW64867.1 - 5.9e-05 22.8 0.0 0.00015 21.5 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RJW64867.1 - 0.0011 19.2 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tyr_Deacylase PF02580.16 RJW64868.1 - 7.2e-52 175.8 0.0 8.1e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase GRASP55_65 PF04495.14 RJW64869.1 - 2.3e-66 222.3 0.0 4.6e-47 159.8 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 RJW64869.1 - 8.7e-09 35.1 0.0 0.0033 17.3 0.0 2.6 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RJW64869.1 - 2.7e-08 34.0 0.0 0.0081 16.5 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 RJW64869.1 - 0.048 14.0 0.0 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 PDZ domain DUF4471 PF14740.6 RJW64870.1 - 5.2e-83 278.8 0.0 3.4e-75 253.1 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4471) DUF4470 PF14737.6 RJW64870.1 - 0.0099 16.0 0.2 0.034 14.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) Cullin PF00888.22 RJW64871.1 - 3.2e-170 567.8 10.6 3.9e-170 567.5 10.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RJW64871.1 - 2.7e-23 81.7 1.3 9e-23 80.1 1.3 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Dpy-30 PF05186.13 RJW64871.1 - 0.016 14.9 0.0 0.051 13.3 0.0 1.8 1 0 0 1 1 1 0 Dpy-30 motif AraC_N PF06719.13 RJW64871.1 - 0.036 13.7 0.7 3 7.5 0.2 2.6 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus CTNNBL PF08216.11 RJW64872.1 - 1.4e-07 31.7 0.1 4.1e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF3384 PF11864.8 RJW64872.1 - 0.0094 14.9 0.0 0.37 9.6 0.0 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF3384) RIH_assoc PF08454.11 RJW64872.1 - 0.037 13.9 0.2 0.59 10.0 0.0 2.7 2 1 0 2 2 2 0 RyR and IP3R Homology associated Ribosomal_S13_N PF08069.12 RJW64872.1 - 0.1 12.7 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain Exo70 PF03081.15 RJW64872.1 - 0.13 11.2 0.1 0.36 9.8 0.0 1.8 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Ldl_recept_a PF00057.18 RJW64875.1 - 0.0026 17.9 3.6 0.0026 17.9 3.6 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Med25_SD1 PF11235.8 RJW64875.1 - 0.42 10.9 2.9 0.98 9.7 0.1 2.5 3 0 0 3 3 3 0 Mediator complex subunit 25 synapsin 1 pPIWI_RE_Y PF18156.1 RJW64876.1 - 1.7 9.1 4.2 1.5 9.2 0.2 2.9 3 1 1 4 4 4 0 pPIWI_RE three-gene island domain Y Pkinase PF00069.25 RJW64877.1 - 9.9e-33 113.6 0.0 4.6e-31 108.1 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 RJW64877.1 - 1.1e-21 77.3 0.1 2.4e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 RJW64877.1 - 1.1e-19 70.7 0.0 3.4e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 RJW64877.1 - 0.0014 18.1 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RJW64877.1 - 0.0034 16.2 0.0 0.0055 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RJW64877.1 - 0.0058 16.6 0.8 0.055 13.4 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF5323 PF17257.2 RJW64877.1 - 0.01 15.7 2.1 0.01 15.7 2.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5323) Kinase-like PF14531.6 RJW64877.1 - 0.22 10.8 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Mito_fiss_reg PF05308.11 RJW64878.1 - 6e-08 33.1 8.4 6e-08 33.1 8.4 3.0 3 1 0 3 3 3 1 Mitochondrial fission regulator MAD PF05557.13 RJW64878.1 - 0.053 11.9 0.3 0.077 11.4 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Cytochrome_C7 PF14522.6 RJW64879.1 - 0.11 12.5 4.3 0.43 10.6 4.8 1.7 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c WD40_alt PF14077.6 RJW64880.1 - 0.48 10.3 3.4 1.3 8.9 0.0 3.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif NAPRTase_N PF17767.1 RJW64880.1 - 0.68 10.3 3.6 0.79 10.1 0.2 2.5 2 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Prenyltransf PF01255.19 RJW64881.1 - 0.14 11.7 0.4 0.28 10.7 0.4 1.4 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase RVT_1 PF00078.27 RJW64882.1 - 6.8e-16 58.4 0.0 9.6e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 RJW64883.1 - 3.2e-27 95.5 0.1 8.3e-15 54.9 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) QRPTase_C PF01729.19 RJW64884.1 - 5.5e-14 52.3 0.0 9.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 RJW64884.1 - 1.1e-11 44.6 0.3 2.8e-11 43.3 0.1 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain zinc_ribbon_2 PF13240.6 RJW64884.1 - 0.027 14.2 4.9 0.05 13.3 4.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 RJW64884.1 - 0.036 14.1 1.8 0.077 13.0 1.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon Forkhead PF00250.18 RJW64886.1 - 8.6e-36 122.1 0.0 2e-35 120.9 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain DJ-1_PfpI PF01965.24 RJW64887.1 - 4.5e-27 94.9 0.1 5.5e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 RJW64887.1 - 0.0079 15.9 0.0 0.35 10.5 0.0 2.2 1 1 1 2 2 2 2 ThiJ/PfpI family-like gag-asp_proteas PF13975.6 RJW64888.1 - 1.8e-13 50.8 0.0 5.3e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RJW64888.1 - 6.5e-12 45.9 0.2 4.8e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease Tn7_Tnp_TnsA_C PF08721.11 RJW64888.1 - 0.00032 21.3 0.1 2.3 8.9 0.0 3.0 2 0 0 2 2 2 2 TnsA endonuclease C terminal RVP PF00077.20 RJW64888.1 - 0.0028 17.9 0.0 3.8 7.9 0.0 2.7 2 0 0 2 2 2 2 Retroviral aspartyl protease HTH_Tnp_Tc3_2 PF01498.18 RJW64888.1 - 0.015 15.5 1.2 9.2 6.6 0.1 3.4 2 0 0 2 2 2 0 Transposase zf-CCHC_4 PF14392.6 RJW64888.1 - 0.19 11.5 15.9 0.81 9.5 3.8 2.7 2 0 0 2 2 2 0 Zinc knuckle Peptidase_A22B PF04258.13 RJW64890.1 - 2.2e-79 266.9 7.1 2.8e-79 266.6 7.1 1.0 1 0 0 1 1 1 1 Signal peptide peptidase Presenilin PF01080.17 RJW64890.1 - 0.039 12.7 10.7 0.19 10.4 3.9 2.2 2 0 0 2 2 2 0 Presenilin Lbh PF15317.6 RJW64891.1 - 0.031 15.1 0.0 0.046 14.6 0.0 1.2 1 0 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein Tctex-1 PF03645.13 RJW64892.1 - 8.7e-26 90.2 0.1 1.1e-25 89.8 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family Proteasome PF00227.26 RJW64892.1 - 0.11 12.0 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Proteasome subunit SNAPc_SNAP43 PF09808.9 RJW64895.1 - 4.4e-33 114.8 0.1 6.9e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 MAD PF05557.13 RJW64896.1 - 1.3e-34 119.6 5.7 1.3e-34 119.6 5.7 3.0 2 1 1 3 3 3 2 Mitotic checkpoint protein Pox_A_type_inc PF04508.12 RJW64896.1 - 0.18 11.7 8.3 0.17 11.8 0.4 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Aida_N PF08910.10 RJW64896.1 - 2.2 8.7 7.6 1.8 9.0 2.1 3.2 3 0 0 3 3 3 0 Aida N-terminus FapA PF03961.13 RJW64896.1 - 6.1 5.3 25.2 1 7.9 0.7 3.1 2 1 1 3 3 3 0 Flagellar Assembly Protein A YojJ PF10372.9 RJW64896.1 - 8.9 6.5 8.1 11 6.2 0.9 3.8 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Ribosomal_S15 PF00312.22 RJW64898.1 - 0.014 15.6 0.6 0.049 13.8 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S15 Fcf2 PF08698.11 RJW64898.1 - 2.5 8.6 6.6 0.3 11.5 0.3 2.6 3 0 0 3 3 3 0 Fcf2 pre-rRNA processing Caldesmon PF02029.15 RJW64899.1 - 0.0038 16.1 53.9 0.0043 15.9 53.9 1.1 1 0 0 1 1 1 1 Caldesmon Utp14 PF04615.13 RJW64899.1 - 0.015 13.9 50.7 0.017 13.7 50.7 1.1 1 0 0 1 1 1 0 Utp14 protein Dapper PF15268.6 RJW64899.1 - 0.28 10.0 62.2 0.29 9.9 62.2 1.1 1 0 0 1 1 1 0 Dapper BAF1_ABF1 PF04684.13 RJW64899.1 - 0.42 9.6 49.2 0.51 9.3 49.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SPX PF03105.19 RJW64899.1 - 0.44 10.4 41.8 0.52 10.2 41.8 1.2 1 0 0 1 1 1 0 SPX domain VIR_N PF15912.5 RJW64899.1 - 3.1 7.3 0.0 3.1 7.3 0.0 2.9 2 1 0 2 2 2 0 Virilizer, N-terminal zf-Tim10_DDP PF02953.15 RJW64900.1 - 1.9e-11 43.4 5.5 4.3e-11 42.3 5.5 1.6 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TUDOR PF00567.24 RJW64900.1 - 0.073 13.1 1.2 0.7 9.9 0.1 2.1 1 1 1 2 2 2 0 Tudor domain MPC PF03650.13 RJW64901.1 - 5.6e-38 129.5 0.3 7.6e-38 129.1 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers 7tm_1 PF00001.21 RJW64903.1 - 3.4e-06 26.6 8.3 6.1e-06 25.7 8.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW64903.1 - 0.013 15.2 14.2 0.0086 15.7 12.7 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PIRT PF15099.6 RJW64903.1 - 0.13 11.9 1.1 0.24 11.0 0.7 1.7 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family Trypsin PF00089.26 RJW64904.1 - 1e-51 175.9 1.6 5.3e-29 101.6 0.0 2.6 3 0 0 3 3 3 2 Trypsin Trypsin_2 PF13365.6 RJW64904.1 - 2.8e-05 25.0 0.1 7.8e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain ECH_1 PF00378.20 RJW64905.1 - 4.2e-55 186.8 0.5 5.1e-55 186.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RJW64905.1 - 5e-30 105.1 0.8 1.5e-28 100.3 0.2 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CxC1 PF18802.1 RJW64906.1 - 0.12 12.5 1.5 0.21 11.8 1.5 1.3 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases TRIQK PF15168.6 RJW64909.1 - 0.35 10.8 3.8 0.7 9.8 3.8 1.4 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Endostatin PF06482.11 RJW64910.1 - 4.6e-71 239.9 0.0 2.4e-59 201.4 0.0 2.1 1 1 1 2 2 2 2 Collagenase NC10 and Endostatin Collagen PF01391.18 RJW64910.1 - 0.0026 17.5 30.2 0.46 10.3 16.9 2.8 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF2724 PF10893.8 RJW64911.1 - 8.6e-09 35.1 0.0 74 3.3 0.0 11.0 16 0 0 16 16 16 0 Protein of unknown function (DUF2724) Ribosomal_S6e PF01092.19 RJW64911.1 - 1.8e-05 24.7 0.0 11 6.1 0.0 4.9 7 0 0 7 7 7 3 Ribosomal protein S6e Ntox35 PF15534.6 RJW64911.1 - 0.01 16.2 0.1 3.6e+02 1.7 0.0 6.8 7 0 0 7 7 7 0 Bacterial toxin 35 YtkA PF13115.6 RJW64911.1 - 0.023 15.3 0.0 3.6e+02 1.9 0.0 5.0 4 0 0 4 4 4 0 YtkA-like DUF4460 PF14687.6 RJW64911.1 - 0.27 11.3 1.1 2.1e+02 2.0 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4460) RRM_3 PF08777.11 RJW64912.1 - 4.5e-05 23.4 0.0 9.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 RJW64912.1 - 0.00036 20.3 0.0 0.00088 19.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRP7 PF12923.7 RJW64912.1 - 0.0017 18.5 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Homeodomain PF00046.29 RJW64913.1 - 2.3e-18 65.8 7.3 4.7e-18 64.8 7.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW64913.1 - 0.011 15.7 0.1 0.031 14.2 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain FYRC PF05965.14 RJW64913.1 - 0.051 13.7 0.1 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 F/Y rich C-terminus 2Fe-2S_thioredx PF01257.19 RJW64913.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Mfa1 PF17445.2 RJW64914.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Mating factor A1 DUF3584 PF12128.8 RJW64915.1 - 0.1 10.1 59.9 0.13 9.7 49.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF2218 PF09981.9 RJW64915.1 - 1.9 8.9 9.4 0.28 11.6 1.9 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) Tubulin PF00091.25 RJW64916.1 - 3.4e-51 174.2 0.0 5.1e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW64916.1 - 4.8e-38 130.2 0.0 8.2e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Ets PF00178.22 RJW64918.1 - 5.2e-34 116.6 1.8 1.1e-33 115.5 1.8 1.6 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.17 RJW64918.1 - 0.046 14.3 0.9 0.2 12.3 0.1 2.5 2 0 0 2 2 2 0 HSF-type DNA-binding Peptidase_S8 PF00082.22 RJW64920.1 - 1.9e-41 142.2 0.8 2.6e-41 141.9 0.8 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 RJW64920.1 - 9.3e-18 64.0 0.0 1.9e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Furin-like_2 PF15913.5 RJW64920.1 - 0.0011 19.1 49.8 0.008 16.3 17.3 5.0 4 1 1 5 5 5 3 Furin-like repeat, cysteine-rich VSP PF03302.13 RJW64920.1 - 1.2 7.9 52.5 0.18 10.6 24.1 3.7 2 1 0 3 3 3 0 Giardia variant-specific surface protein Clathrin PF00637.20 RJW64922.1 - 7.8e-07 29.1 0.5 0.00011 22.0 0.1 2.7 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 RJW64922.1 - 5.3e-06 26.2 9.6 2.6e-05 23.9 9.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW64922.1 - 0.0012 19.2 8.6 0.0012 19.2 8.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 RJW64922.1 - 0.005 16.7 9.6 0.012 15.5 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 RJW64922.1 - 0.043 14.3 1.0 0.28 11.6 1.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 TMF_DNA_bd PF12329.8 RJW64922.1 - 0.094 12.7 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-C3H2C3 PF17122.5 RJW64922.1 - 0.23 11.6 14.6 0.052 13.6 10.7 2.0 2 0 0 2 2 2 0 Zinc-finger zf-RING_5 PF14634.6 RJW64922.1 - 0.49 10.4 8.6 1.2 9.2 8.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RJW64922.1 - 0.69 9.8 6.9 1.5 8.7 6.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW64922.1 - 1.9 8.9 13.0 0.13 12.5 7.4 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 RJW64922.1 - 3.4 8.0 7.5 8.9 6.7 7.5 1.7 1 0 0 1 1 1 0 RING-like domain RVT_1 PF00078.27 RJW64925.1 - 1.5e-37 129.3 0.0 2.8e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VHL PF01847.16 RJW64927.1 - 0.00079 19.3 0.0 0.76 9.7 0.0 2.7 2 0 0 2 2 2 2 VHL beta domain HTH_18 PF12833.7 RJW64927.1 - 0.026 14.8 1.5 1.8 8.9 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AraC PF00165.23 RJW64927.1 - 0.033 14.3 10.3 0.52 10.5 0.3 4.1 4 0 0 4 4 4 0 Bacterial regulatory helix-turn-helix proteins, AraC family Peptidase_M1 PF01433.20 RJW64927.1 - 0.1 12.1 0.3 11 5.5 0.1 2.3 2 0 0 2 2 2 0 Peptidase family M1 domain zf-TAZ PF02135.16 RJW64927.1 - 0.11 13.0 0.4 0.37 11.3 0.4 1.8 1 0 0 1 1 1 0 TAZ zinc finger DUF1604 PF07713.13 RJW64928.1 - 1.2e-33 114.7 1.3 6e-33 112.5 1.3 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) TB2_DP1_HVA22 PF03134.19 RJW64929.1 - 9.7e-24 83.1 2.3 1.7e-23 82.4 2.3 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MAP65_ASE1 PF03999.12 RJW64933.1 - 5.4e-17 61.7 0.0 6.1e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Arfaptin PF06456.13 RJW64933.1 - 0.023 14.3 0.8 0.62 9.6 0.0 2.0 1 1 0 2 2 2 0 Arfaptin-like domain FANCI_S1-cap PF14674.6 RJW64933.1 - 0.12 12.5 2.8 11 6.2 0.0 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap Usp PF00582.26 RJW64935.1 - 3.8e-29 102.0 0.0 4.3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Ank_2 PF12796.7 RJW64937.1 - 8.4e-15 55.1 0.0 1.2e-06 29.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW64937.1 - 5.7e-14 50.9 0.6 0.035 14.6 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 RJW64937.1 - 7.2e-11 42.4 0.5 0.0012 19.3 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW64937.1 - 2.6e-10 40.3 0.3 0.006 16.9 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RJW64937.1 - 9.1e-07 29.1 0.9 1.4 9.5 0.0 4.6 5 1 0 5 5 5 2 Ankyrin repeat Ribosomal_S2 PF00318.20 RJW64938.1 - 8.7e-27 93.8 1.5 3.4e-13 49.3 0.5 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 DUF4344 PF14247.6 RJW64941.1 - 0.025 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase Phospholip_A2_2 PF05826.12 RJW64942.1 - 1.6e-16 60.3 6.6 2.6e-16 59.6 6.6 1.3 1 0 0 1 1 1 1 Phospholipase A2 USP7_C2 PF14533.6 RJW64943.1 - 1.1e-54 185.3 0.0 2.4e-54 184.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 RJW64943.1 - 4.7e-45 154.1 0.2 6.6e-45 153.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW64943.1 - 3.7e-19 69.5 0.0 1.1e-18 67.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 RJW64943.1 - 3.3e-18 65.9 0.0 1.8e-10 40.6 0.0 3.7 4 0 0 4 4 4 3 ICP0-binding domain of Ubiquitin-specific protease 7 MATH PF00917.26 RJW64943.1 - 5.8e-12 45.8 0.0 1.4e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 MATH domain SVIP PF15811.5 RJW64944.1 - 4.7e-15 55.8 7.8 6.8e-15 55.3 7.8 1.3 1 0 0 1 1 1 1 Small VCP/p97-interacting protein EF-G-binding_N PF07299.11 RJW64945.1 - 0.17 12.4 0.0 0.32 11.6 0.0 1.5 1 1 0 1 1 1 0 Elongation factor G-binding protein, N-terminal SET PF00856.28 RJW64946.1 - 6.5e-16 59.2 0.0 1.1e-14 55.1 0.0 2.2 1 1 0 1 1 1 1 SET domain Memo PF01875.17 RJW64948.1 - 4.9e-21 75.1 0.0 7.9e-21 74.4 0.0 1.4 1 1 0 1 1 1 1 Memo-like protein VGCC_beta4Aa_N PF12052.8 RJW64948.1 - 0.21 11.7 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal ADK PF00406.22 RJW64949.1 - 5.2e-36 124.0 0.0 3.8e-18 66.0 0.0 3.8 3 1 0 3 3 3 3 Adenylate kinase AAA_17 PF13207.6 RJW64949.1 - 1.1e-32 113.3 0.1 1.5e-13 51.3 0.0 4.1 3 1 0 3 3 3 3 AAA domain AAA_18 PF13238.6 RJW64949.1 - 1.1e-16 61.6 0.0 1.1e-06 29.2 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_33 PF13671.6 RJW64949.1 - 1.9e-10 41.0 0.0 0.0064 16.7 0.0 3.7 3 2 0 3 3 3 2 AAA domain AAA PF00004.29 RJW64949.1 - 1e-08 35.7 0.0 0.04 14.3 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RJW64949.1 - 2.5e-07 31.1 0.0 0.09 13.0 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 RJW64949.1 - 2.3e-06 27.9 0.0 0.025 14.8 0.0 3.6 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 RJW64949.1 - 1.4e-05 24.4 0.0 0.0022 17.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 RJW64949.1 - 4.2e-05 23.6 0.0 0.078 13.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RJW64949.1 - 6.9e-05 23.3 0.0 0.017 15.5 0.0 3.2 4 0 0 4 4 3 1 AAA ATPase domain NACHT PF05729.12 RJW64949.1 - 0.00019 21.4 0.0 0.035 14.0 0.0 3.3 3 1 0 3 3 3 1 NACHT domain KTI12 PF08433.10 RJW64949.1 - 0.0002 20.9 0.0 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 Chromatin associated protein KTI12 RNA_helicase PF00910.22 RJW64949.1 - 0.00028 21.3 0.4 1.3 9.4 0.0 4.4 4 1 1 5 5 5 1 RNA helicase AAA_19 PF13245.6 RJW64949.1 - 0.00043 20.6 0.0 2.7 8.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 RJW64949.1 - 0.0025 17.2 0.0 0.73 9.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 RJW64949.1 - 0.0055 16.6 0.0 0.78 9.6 0.0 3.0 3 0 0 3 3 3 1 P-loop Nucleotide Kinase3 Thymidylate_kin PF02223.17 RJW64949.1 - 0.0058 16.3 0.3 1.6 8.4 0.0 3.3 4 0 0 4 4 3 1 Thymidylate kinase AAA_24 PF13479.6 RJW64949.1 - 0.013 15.2 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 RJW64949.1 - 0.017 15.0 0.8 2.4 8.0 0.0 3.2 3 0 0 3 3 3 0 Deoxynucleoside kinase SKI PF01202.22 RJW64949.1 - 0.021 14.9 0.1 2.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase CPT PF07931.12 RJW64949.1 - 0.034 14.0 0.0 3.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein ATP_bind_1 PF03029.17 RJW64949.1 - 0.047 13.5 0.3 0.83 9.4 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 RJW64949.1 - 0.048 13.3 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PRK PF00485.18 RJW64949.1 - 0.053 13.2 0.0 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 RJW64949.1 - 0.067 12.8 0.0 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 RJW64949.1 - 0.11 12.4 0.0 0.82 9.7 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 RJW64949.1 - 0.18 11.9 0.0 6 7.0 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 RJW64949.1 - 0.18 11.9 0.0 0.56 10.3 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase-like family DEAD PF00270.29 RJW64950.1 - 7.3e-23 81.2 0.0 1.2e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW64950.1 - 1.9e-22 79.7 0.0 3.5e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW64950.1 - 0.00082 19.4 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RJW64950.1 - 0.0072 16.7 0.0 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RJW64950.1 - 0.03 14.1 0.0 0.066 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain ASC PF00858.24 RJW64951.1 - 1.2e-18 67.4 0.4 1.5e-18 67.0 0.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel UBM PF14377.6 RJW64951.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin binding region CD52 PF15116.6 RJW64951.1 - 0.2 11.7 1.0 0.46 10.6 1.0 1.6 1 0 0 1 1 1 0 CAMPATH-1 antigen ASC PF00858.24 RJW64952.1 - 3.9e-44 151.4 2.0 3.9e-44 151.4 2.0 1.6 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel Med12-LCEWAV PF12145.8 RJW64954.1 - 4.2e-71 240.2 3.5 4.5e-69 233.6 3.5 2.5 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 RJW64954.1 - 2.1e-11 44.0 0.1 5.8e-11 42.5 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 NOB1_Zn_bind PF08772.11 RJW64955.1 - 0.053 13.7 0.6 0.11 12.6 0.6 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like HRG PF16954.5 RJW64956.1 - 0.11 12.9 0.0 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene NHL PF01436.21 RJW64957.1 - 8.6e-10 38.2 0.5 4.9e-07 29.5 0.0 3.6 3 0 0 3 3 3 2 NHL repeat WD40 PF00400.32 RJW64959.1 - 3.5e-19 68.8 9.8 5.9e-09 36.4 0.0 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW64959.1 - 2.3e-06 27.8 0.0 0.0082 16.4 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW64959.1 - 0.00032 19.8 0.1 0.17 10.9 0.0 2.1 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Sulfotransfer_1 PF00685.27 RJW64959.1 - 0.25 10.8 0.0 0.33 10.4 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain HSP90 PF00183.18 RJW64960.1 - 3.6e-199 662.9 14.1 3.6e-199 662.9 14.1 2.9 3 1 1 4 4 4 1 Hsp90 protein HATPase_c_3 PF13589.6 RJW64960.1 - 8.9e-11 41.8 0.2 5e-10 39.3 0.2 2.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RJW64960.1 - 2e-10 41.2 1.8 2.1e-10 41.1 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PurA PF04845.13 RJW64962.1 - 5.5e-66 222.0 0.3 6.8e-66 221.7 0.3 1.1 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 RJW64962.1 - 0.00013 22.1 8.1 0.18 12.0 1.4 3.6 2 1 1 3 3 3 3 Protein of unknown function (DUF3276) WD40 PF00400.32 RJW64963.1 - 2e-15 56.9 10.3 4.3e-06 27.4 0.2 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW64963.1 - 1.6e-06 28.3 0.3 0.11 12.8 0.1 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RJW64963.1 - 0.017 14.5 0.0 0.057 12.7 0.0 1.8 2 1 0 2 2 2 0 WD40-like domain Prefoldin_2 PF01920.20 RJW64964.1 - 2.1e-21 75.8 1.5 2.8e-21 75.5 1.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Med2 PF11214.8 RJW64964.1 - 0.024 14.8 1.3 0.72 10.0 0.2 2.2 2 0 0 2 2 2 0 Mediator complex subunit 2 BAR_3 PF16746.5 RJW64964.1 - 0.025 14.3 0.5 0.033 13.9 0.5 1.1 1 0 0 1 1 1 0 BAR domain of APPL family Toxin-deaminase PF14424.6 RJW64964.1 - 0.056 13.5 0.4 0.09 12.9 0.2 1.5 1 1 0 1 1 1 0 The BURPS668_1122 family of deaminases DUF5082 PF16888.5 RJW64964.1 - 0.16 12.3 3.1 7 7.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ZapB PF06005.12 RJW64964.1 - 0.41 11.1 3.8 0.45 11.0 0.3 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Dynein_light PF01221.18 RJW64967.1 - 8.5e-36 122.1 0.2 9.3e-36 122.0 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Swm2 PF17083.5 RJW64967.1 - 0.022 14.7 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 Dynein_light PF01221.18 RJW64969.1 - 2.8e-16 59.6 0.4 4.2e-16 59.0 0.4 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Stonin2_N PF12016.8 RJW64969.1 - 0.0043 16.5 1.5 0.0066 15.9 1.5 1.2 1 0 0 1 1 1 1 Stonin 2 Tri3 PF07428.11 RJW64969.1 - 0.087 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 Dynein_light PF01221.18 RJW64970.1 - 8.1e-28 96.6 2.8 8.9e-28 96.4 2.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 RJW64970.1 - 0.0045 16.8 0.1 0.005 16.6 0.1 1.2 1 0 0 1 1 1 1 Immunity protein 48 Dynein_light PF01221.18 RJW64971.1 - 9.6e-28 96.3 0.9 1e-27 96.2 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 RJW64971.1 - 0.007 15.9 0.0 0.0081 15.6 0.0 1.0 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Cytidylate_kin PF02224.18 RJW64971.1 - 0.025 14.3 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase Ecotin PF03974.13 RJW64971.1 - 0.086 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Ecotin CD36 PF01130.21 RJW64972.1 - 2.8e-123 411.9 0.5 3.4e-123 411.6 0.5 1.0 1 0 0 1 1 1 1 CD36 family PorA PF11271.8 RJW64972.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Porin PorA B12D PF06522.11 RJW64972.1 - 0.11 12.3 0.4 0.39 10.5 0.4 2.0 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RT_RNaseH PF17917.1 RJW64973.1 - 7e-10 39.1 0.2 1e-09 38.6 0.2 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW64973.1 - 4.7e-06 26.6 0.0 8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ribosomal_L14e PF01929.17 RJW64974.1 - 1.4e-31 108.8 1.6 2.5e-31 108.0 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 RJW64974.1 - 0.004 17.1 0.2 0.0078 16.1 0.2 1.5 1 0 0 1 1 1 1 KOW motif zf-RING_2 PF13639.6 RJW64977.1 - 1.3e-08 35.0 13.3 1.3e-08 35.0 13.3 2.6 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 RJW64977.1 - 1.5e-07 31.2 9.7 1.5e-07 31.2 9.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW64977.1 - 5.3e-07 29.4 12.7 5.3e-07 29.4 12.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW64977.1 - 7.3e-06 25.7 13.0 7.3e-06 25.7 13.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW64977.1 - 1.6e-05 25.1 7.0 1.6e-05 25.1 7.0 3.0 3 0 0 3 3 3 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RJW64977.1 - 0.0017 18.1 11.7 0.0056 16.5 11.7 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 RJW64977.1 - 0.0058 16.4 6.8 0.0058 16.4 6.8 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RJW64977.1 - 0.024 14.6 11.9 0.098 12.7 11.9 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 RJW64977.1 - 0.33 11.0 5.2 1.1 9.4 5.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C2-set_2 PF08205.12 RJW64978.1 - 0.0055 16.8 0.2 1.1 9.4 0.0 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ins134_P3_kin_N PF17927.1 RJW64979.1 - 0.2 12.1 0.0 30 5.1 0.0 2.5 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain HCO3_cotransp PF00955.21 RJW64980.1 - 8.8e-159 529.6 7.6 1.1e-158 529.3 7.6 1.0 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.22 RJW64980.1 - 0.0087 16.0 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.13 RJW64980.1 - 0.0098 15.7 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain CrgA PF06781.12 RJW64980.1 - 2.3 8.3 6.7 6.6 6.9 0.2 3.2 3 0 0 3 3 3 0 Cell division protein CrgA Linker_histone PF00538.19 RJW64981.1 - 1.2e-08 35.2 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF848 PF05852.11 RJW64983.1 - 0.6 10.2 4.2 0.33 11.1 0.8 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) MFS_1 PF07690.16 RJW64984.1 - 6.2e-22 78.0 33.0 2.8e-17 62.7 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L2_C PF03947.18 RJW64985.1 - 7.4e-47 158.7 4.0 1.6e-46 157.6 3.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RJW64985.1 - 1.5e-19 69.7 1.7 1.9e-19 69.4 0.2 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain GCD14 PF08704.10 RJW64986.1 - 5.1e-73 245.8 0.0 1e-69 234.9 0.0 2.0 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 RJW64986.1 - 2.9e-07 30.4 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RJW64986.1 - 2.1e-06 27.7 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 RJW64986.1 - 5.8e-06 26.9 0.0 1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 RJW64986.1 - 0.0066 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_11 PF08241.12 RJW64986.1 - 0.031 14.9 0.0 0.055 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RJW64986.1 - 0.036 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 RJW64986.1 - 0.24 10.7 0.0 0.42 9.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family OTU PF02338.19 RJW64987.1 - 1.7e-24 86.7 0.0 5e-24 85.2 0.0 1.7 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RJW64987.1 - 7.5e-07 28.9 0.0 0.00014 21.4 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain KN_motif PF12075.8 RJW64987.1 - 0.25 11.2 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 KN motif Spectrin PF00435.21 RJW64988.1 - 9.7e-34 116.0 137.1 5e-08 33.4 7.0 19.1 18 3 0 19 19 19 10 Spectrin repeat CH PF00307.31 RJW64988.1 - 3.8e-12 46.4 0.0 3.9e-11 43.1 0.0 2.9 2 0 0 2 2 2 1 Calponin homology (CH) domain PH_9 PF15410.6 RJW64988.1 - 5.2e-12 46.2 0.0 1.9e-11 44.4 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 RJW64988.1 - 7.1e-05 23.3 0.0 0.00034 21.1 0.0 2.3 1 0 0 1 1 1 1 PH domain CAMSAP_CH PF11971.8 RJW64988.1 - 0.00082 19.2 0.0 0.0037 17.1 0.0 2.2 1 0 0 1 1 1 1 CAMSAP CH domain PB1 PF00564.24 RJW64988.1 - 0.025 14.5 0.0 0.38 10.7 0.0 3.2 1 0 0 1 1 1 0 PB1 domain DUF3800 PF12686.7 RJW64988.1 - 0.041 14.5 0.1 2.4e+02 2.4 0.1 5.7 4 3 0 5 5 5 0 Protein of unknown function (DUF3800) Chlamy_scaf PF09675.10 RJW64988.1 - 0.12 12.8 0.2 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Med3 PF11593.8 RJW64988.1 - 3.2 6.8 5.0 0.58 9.3 1.1 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal GST_C_3 PF14497.6 RJW64989.1 - 4.8e-17 62.0 0.1 6.9e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RJW64989.1 - 6.4e-11 42.3 0.1 1.1e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RJW64989.1 - 1.2e-05 25.2 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RJW64989.1 - 4.2e-05 23.8 0.2 0.00034 20.9 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RJW64989.1 - 0.00048 20.5 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RJW64989.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1804 PF08822.11 RJW64989.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) NifU_N PF01592.16 RJW64991.1 - 4.1e-57 191.9 0.1 4.7e-57 191.7 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF3659 PF12396.8 RJW64991.1 - 0.14 12.1 0.2 2.7 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) RVT_1 PF00078.27 RJW64993.1 - 5.7e-05 22.7 0.0 0.00023 20.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TrbC_Ftype PF09673.10 RJW64995.1 - 0.0083 16.2 0.1 3.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Type-F conjugative transfer system pilin assembly protein Pkinase PF00069.25 RJW64996.1 - 9.7e-74 248.0 0.0 1.3e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW64996.1 - 1.3e-44 152.5 0.0 1.7e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW64996.1 - 2.9e-07 30.1 0.0 7.4e-07 28.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RJW64996.1 - 0.00046 19.8 0.4 0.00075 19.2 0.4 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RJW64996.1 - 0.01 15.2 0.4 0.018 14.4 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RJW64996.1 - 0.018 14.0 0.1 0.029 13.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain UBA PF00627.31 RJW64996.1 - 0.1 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Trypsin PF00089.26 RJW64997.1 - 2e-06 27.8 0.0 3.8e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Trypsin Mdv1 PF11542.8 RJW64997.1 - 0.3 11.1 1.8 0.61 10.1 1.8 1.5 1 0 0 1 1 1 0 Mitochondrial division protein 1 P21-Arc PF04062.14 RJW64998.1 - 5.2e-59 199.2 0.0 7.1e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Pkinase PF00069.25 RJW64999.1 - 1.5e-06 27.8 0.0 0.00011 21.6 0.0 2.9 2 0 0 2 2 2 2 Protein kinase domain GIT_CC PF16559.5 RJW64999.1 - 3.8 7.4 11.0 2.8 7.9 0.1 3.6 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CytoC_RC PF02276.18 RJW65000.1 - 0.0071 15.7 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Photosynthetic reaction centre cytochrome C subunit Alpha_kinase PF02816.18 RJW65001.1 - 9.7e-59 198.6 0.1 1.5e-58 197.9 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 RJW65001.1 - 2e-08 34.6 6.4 0.0028 18.3 0.5 4.7 4 0 0 4 4 4 2 Sel1 repeat WD40 PF00400.32 RJW65002.1 - 0.077 13.9 4.8 2 9.4 0.6 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat WD40_like PF17005.5 RJW65002.1 - 0.13 11.6 0.0 1.9 7.8 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain Gp_dh_N PF00044.24 RJW65003.1 - 2.7e-19 69.4 0.0 1.1e-18 67.4 0.0 2.1 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 RJW65003.1 - 1.7e-13 50.4 0.0 3.5e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain STPPase_N PF16891.5 RJW65004.1 - 0.11 13.0 0.1 14 6.2 0.0 2.9 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain DUF438 PF04282.13 RJW65004.1 - 0.12 12.4 0.3 18 5.4 0.2 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF438) SAM_Exu PF18609.1 RJW65004.1 - 0.17 12.0 1.8 22 5.2 0.1 2.9 2 0 0 2 2 2 0 Exuperantia SAM-like domain ASC PF00858.24 RJW65005.1 - 2.6e-20 72.8 0.1 3.5e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 RJW65008.1 - 1.2e-32 113.5 3.9 4.8e-32 111.5 3.9 1.7 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel TPR_8 PF13181.6 RJW65009.1 - 0.00028 20.9 6.1 0.0015 18.6 0.8 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RJW65009.1 - 0.0012 18.6 0.7 0.0035 17.1 0.7 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 RJW65009.1 - 0.0013 19.2 0.2 0.0013 19.2 0.2 3.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW65009.1 - 0.0016 18.4 0.6 0.0016 18.4 0.6 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW65009.1 - 0.014 15.6 0.4 0.039 14.2 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RJW65009.1 - 0.045 14.3 2.6 2.1 8.9 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Uteroglobin PF01099.17 RJW65009.1 - 0.13 12.6 2.9 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 Uteroglobin family BIV_Env PF05858.12 RJW65011.1 - 0.015 13.5 0.0 0.024 12.8 0.0 1.3 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) T6SS_TssF PF05947.12 RJW65012.1 - 0.0011 17.7 3.5 0.0016 17.1 3.5 1.2 1 0 0 1 1 1 1 Type VI secretion system, TssF BEN PF10523.9 RJW65012.1 - 0.0022 18.2 0.0 0.0063 16.7 0.0 1.8 2 0 0 2 2 2 1 BEN domain JAKMIP_CC3 PF16034.5 RJW65012.1 - 0.0096 15.9 0.3 0.023 14.7 0.3 1.6 1 0 0 1 1 1 1 JAKMIP CC3 domain Cep57_MT_bd PF06657.13 RJW65012.1 - 0.011 16.2 0.3 0.056 13.9 0.3 2.2 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 GDPD PF03009.17 RJW65013.1 - 4.5e-18 65.9 0.4 7.6e-18 65.2 0.4 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 RJW65013.1 - 2.3e-06 27.4 0.0 5.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain PI-PLC-X PF00388.19 RJW65013.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Trypsin PF00089.26 RJW65014.1 - 5.3e-14 52.6 0.0 6.7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 RJW65014.1 - 0.084 13.3 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) dCMP_cyt_deam_1 PF00383.23 RJW65015.1 - 6.1e-15 54.9 2.5 7.5e-15 54.7 2.5 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 RJW65015.1 - 4.5e-08 33.4 1.8 4.5e-08 33.4 1.8 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Nop53 PF07767.11 RJW65016.1 - 0.022 14.2 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Diphthami_syn_2 PF01902.17 RJW65017.1 - 5.3e-22 78.4 0.0 8.5e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Diphthamide synthase TAFII28 PF04719.14 RJW65018.1 - 0.62 10.2 3.4 0.96 9.6 1.0 2.2 2 0 0 2 2 2 0 hTAFII28-like protein conserved region Cg6151-P PF10233.9 RJW65019.1 - 6.4e-10 39.3 4.9 7.2e-10 39.2 4.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P E1-E2_ATPase PF00122.20 RJW65019.1 - 0.036 13.6 0.7 0.048 13.2 0.7 1.3 1 1 0 1 1 1 0 E1-E2 ATPase TraL PF07178.11 RJW65019.1 - 0.058 13.9 0.6 0.058 13.9 0.6 1.6 2 0 0 2 2 2 0 TraL protein EmrE PF13536.6 RJW65021.1 - 0.07 12.7 0.0 0.072 12.7 0.0 1.0 1 0 0 1 1 1 0 Putative multidrug resistance efflux transporter RVT_1 PF00078.27 RJW65027.1 - 9.9e-13 48.1 0.1 1.5e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 RJW65027.1 - 1.4e-08 34.6 0.0 3.4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW65027.1 - 1.7e-05 25.0 0.0 4.6e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Arteri_GP4 PF02497.15 RJW65027.1 - 0.06 13.5 0.4 0.084 13.0 0.4 1.2 1 0 0 1 1 1 0 Arterivirus glycoprotein Herpes_UL43 PF05072.13 RJW65028.1 - 0.005 16.0 0.3 0.018 14.2 0.2 1.7 2 0 0 2 2 2 1 Herpesvirus UL43 protein TxDE PF18711.1 RJW65030.1 - 0.15 12.2 0.0 0.56 10.4 0.0 2.0 2 0 0 2 2 2 0 Toxoflavin-degrading enzyme bZIP_1 PF00170.21 RJW65031.1 - 2.2e-13 50.1 7.2 4.1e-13 49.2 7.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RJW65031.1 - 2e-07 31.0 8.4 3.6e-07 30.2 8.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RJW65031.1 - 8.1e-05 23.1 8.8 0.00018 22.0 8.8 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor zf-CCCH PF00642.24 RJW65036.1 - 1.2e-05 25.1 11.8 0.014 15.3 1.1 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RJW65036.1 - 8.9e-05 22.4 10.3 0.003 17.6 1.1 3.6 3 1 0 3 3 3 2 Zinc finger domain zf-C3H1 PF10650.9 RJW65036.1 - 0.12 12.2 5.4 0.56 10.0 2.4 2.6 2 0 0 2 2 2 0 Putative zinc-finger domain Torus PF16131.5 RJW65036.1 - 0.14 12.8 11.6 0.35 11.6 0.7 3.0 2 1 1 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 RJW65036.1 - 0.22 11.8 6.5 0.63 10.3 6.5 1.8 1 0 0 1 1 1 0 Zinc-finger containing family Glyco_hydro_130 PF04041.13 RJW65037.1 - 0.031 13.2 0.1 0.06 12.3 0.1 1.4 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase TCR PF03638.15 RJW65038.1 - 2e-21 76.0 60.3 1.2e-11 44.6 23.6 2.7 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 RJW65038.1 - 0.026 14.7 47.2 0.65 10.2 20.0 2.8 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 BING4CT PF08149.11 RJW65039.1 - 1.6e-31 108.0 0.1 1e-30 105.3 0.0 2.5 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 RJW65039.1 - 3.9e-07 30.6 2.5 0.00012 22.8 0.2 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat SNF PF00209.18 RJW65040.1 - 4.8e-174 579.9 27.9 6.8e-174 579.4 27.9 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3938 PF13074.6 RJW65041.1 - 0.14 12.5 5.8 0.087 13.1 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3938) ABC2_membrane_5 PF13346.6 RJW65041.1 - 0.16 11.5 16.0 0.2 11.2 16.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Fungal_trans PF04082.18 RJW65041.1 - 0.18 10.8 0.1 0.2 10.7 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain ECSCR PF15820.5 RJW65041.1 - 0.27 11.1 10.2 0.81 9.5 0.8 2.6 1 1 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator PAG PF15347.6 RJW65041.1 - 0.27 10.2 0.6 0.38 9.7 0.6 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched DUF5392 PF17370.2 RJW65041.1 - 0.57 10.3 4.4 0.33 11.0 2.6 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5392) DUF4381 PF14316.6 RJW65041.1 - 1.9 8.8 5.9 1.5 9.0 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) HlyIII PF03006.20 RJW65041.1 - 2.7 7.6 12.6 4.5 6.9 12.6 1.4 1 1 0 1 1 1 0 Haemolysin-III related DUF2070 PF09843.9 RJW65041.1 - 5.9 5.1 14.3 7.5 4.7 14.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TssN PF17555.2 RJW65041.1 - 8.2 5.7 10.5 1.8 7.9 5.2 1.7 1 1 1 2 2 2 0 Type VI secretion system, TssN RMP PF14996.6 RJW65042.1 - 2.9e-34 118.5 8.4 3.2e-34 118.4 8.4 1.0 1 0 0 1 1 1 1 Retinal Maintenance UPAR_LY6_2 PF16975.5 RJW65042.1 - 0.04 14.1 3.8 0.059 13.6 3.8 1.3 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 La PF05383.17 RJW65042.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 La domain zf-H2C2_2 PF13465.6 RJW65043.1 - 0.0013 19.1 1.4 0.0013 19.1 1.4 4.6 5 1 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.26 RJW65043.1 - 0.0019 18.6 24.4 0.008 16.6 3.2 4.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW65043.1 - 0.095 13.6 22.0 0.32 11.9 2.5 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger GluR_Homer-bdg PF10606.9 RJW65043.1 - 0.1 12.8 0.1 0.43 10.8 0.1 2.1 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor zf-C2H2_6 PF13912.6 RJW65043.1 - 2.7 8.1 20.0 0.21 11.6 0.5 4.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW65044.1 - 5.6e-17 61.2 46.5 5.8e-05 23.3 1.3 6.9 6 1 1 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW65044.1 - 1.1e-11 44.6 42.4 0.018 15.8 0.8 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW65044.1 - 4.1e-11 42.8 36.1 0.00017 21.9 0.2 6.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW65044.1 - 1.9e-08 34.1 28.3 0.0014 18.6 1.0 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW65044.1 - 2.5e-05 24.4 18.7 0.22 11.9 0.0 5.8 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RJW65044.1 - 6.4e-05 22.6 22.0 0.0058 16.4 0.2 5.3 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-met PF12874.7 RJW65044.1 - 0.0067 16.8 19.8 2.3 8.7 0.2 6.6 6 0 0 6 6 6 1 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 RJW65044.1 - 0.013 16.2 19.7 0.11 13.2 1.6 3.6 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Trm112p PF03966.16 RJW65044.1 - 0.015 15.9 5.2 3.3 8.3 0.2 3.3 3 1 0 3 3 3 0 Trm112p-like protein DUF2256 PF10013.9 RJW65044.1 - 0.02 15.0 13.7 1.3 9.2 0.2 5.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) XPA_N PF01286.18 RJW65044.1 - 0.055 13.5 0.1 0.055 13.5 0.1 4.2 5 0 0 5 5 5 0 XPA protein N-terminal ADK_lid PF05191.14 RJW65044.1 - 0.06 13.3 9.0 8.5 6.5 3.6 4.2 2 1 1 3 3 3 0 Adenylate kinase, active site lid Zn-C2H2_12 PF18112.1 RJW65044.1 - 0.16 12.4 4.7 0.63 10.6 0.1 4.0 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-RRPl_C4 PF17026.5 RJW65044.1 - 0.28 11.3 9.4 0.44 10.7 3.9 2.3 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf_C2H2_ZHX PF18387.1 RJW65044.1 - 0.38 10.4 17.3 0.64 9.7 0.4 4.6 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain FYDLN_acid PF09538.10 RJW65044.1 - 0.42 11.3 12.2 3.8 8.2 5.2 3.9 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) zf-C2H2_2 PF12756.7 RJW65044.1 - 0.49 10.7 32.7 2.1 8.7 0.4 5.8 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RJW65044.1 - 1.5 9.0 18.7 0.27 11.4 1.9 4.2 2 2 1 3 3 3 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 RJW65044.1 - 1.6 8.7 10.8 0.24 11.4 0.5 4.0 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-LYAR PF08790.11 RJW65044.1 - 5.4 7.0 20.8 0.67 9.9 0.7 5.0 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger FOXP-CC PF16159.5 RJW65044.1 - 8.9 7.0 16.3 2.5 8.8 2.5 3.8 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-MYST PF17772.1 RJW65044.1 - 9.5 5.9 9.8 5.5 6.7 0.1 4.1 3 2 2 5 5 5 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 RJW65044.1 - 9.6 7.0 17.2 9.2 7.1 3.0 3.4 1 1 2 3 3 3 0 zinc-ribbon family SpoU_methylase PF00588.19 RJW65045.1 - 2.4e-22 79.6 0.0 5.7e-22 78.4 0.0 1.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 RJW65045.1 - 0.0068 16.7 0.0 0.015 15.5 0.0 1.6 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding SKI PF01202.22 RJW65046.1 - 2.5e-16 60.2 0.0 2.9e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 RJW65046.1 - 2.1e-09 38.0 0.0 1.8e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RJW65046.1 - 8.5e-09 35.7 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 RJW65046.1 - 1.4e-05 25.2 0.0 2.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA PF00004.29 RJW65046.1 - 3.1e-05 24.4 0.2 0.00023 21.6 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 RJW65046.1 - 5.8e-05 22.9 0.0 0.00012 21.9 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 RJW65046.1 - 0.00018 21.7 0.0 0.00024 21.3 0.0 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_28 PF13521.6 RJW65046.1 - 0.00039 20.7 0.0 0.0056 16.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 RJW65046.1 - 0.0016 18.4 0.1 0.0045 16.9 0.1 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain CoaE PF01121.20 RJW65046.1 - 0.0023 17.7 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase dNK PF01712.19 RJW65046.1 - 0.0051 16.7 0.0 0.017 15.0 0.0 1.8 1 1 0 2 2 2 1 Deoxynucleoside kinase AAA_17 PF13207.6 RJW65046.1 - 0.0057 17.1 0.0 0.027 14.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RJW65046.1 - 0.027 15.0 0.1 0.046 14.2 0.1 1.4 1 1 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 RJW65046.1 - 0.031 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_5 PF07728.14 RJW65046.1 - 0.033 14.2 0.1 0.1 12.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RJW65046.1 - 0.037 14.3 0.1 0.053 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RJW65046.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 RJW65046.1 - 0.075 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase 6PF2K PF01591.18 RJW65046.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RuvB_N PF05496.12 RJW65046.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PRK PF00485.18 RJW65046.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Kelch_1 PF01344.25 RJW65047.1 - 5.4e-66 218.0 7.0 1.7e-14 53.1 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RJW65047.1 - 2.2e-38 129.3 5.4 4.1e-08 33.2 0.0 7.0 3 2 4 7 7 7 6 Kelch motif BTB PF00651.31 RJW65047.1 - 1.7e-23 82.9 0.0 3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RJW65047.1 - 1.7e-21 76.2 6.4 1.6e-18 66.7 0.6 3.0 3 0 0 3 3 3 2 BTB And C-terminal Kelch Kelch_2 PF07646.15 RJW65047.1 - 3e-20 71.3 5.0 0.0009 19.1 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RJW65047.1 - 1.4e-16 60.3 7.9 0.00094 19.4 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 RJW65047.1 - 6.3e-13 48.5 3.2 0.0081 16.1 0.0 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW65047.1 - 3e-09 36.7 4.2 0.018 15.1 0.0 5.2 5 0 0 5 5 5 3 Kelch motif DUF3342 PF11822.8 RJW65047.1 - 0.00019 21.5 0.1 0.046 13.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) UQ_con PF00179.26 RJW65048.1 - 1.7e-10 40.7 0.0 1e-08 34.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 RJW65048.1 - 0.039 14.2 0.1 0.066 13.5 0.1 1.5 1 1 0 1 1 1 0 RWD domain DUF799 PF05643.11 RJW65048.1 - 0.14 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) RabGAP-TBC PF00566.18 RJW65054.1 - 4.8e-42 144.0 1.9 6.7e-42 143.6 1.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 RJW65057.1 - 1.2e-27 95.5 14.8 2.9e-05 24.8 0.1 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.11 RJW65057.1 - 3.8e-05 22.6 0.8 0.013 14.3 0.1 3.0 2 1 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 RJW65057.1 - 0.0024 16.6 1.7 0.2 10.3 0.1 3.3 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RJW65057.1 - 0.02 15.2 0.1 0.34 11.2 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF929 PF06053.11 RJW65062.1 - 0.088 12.1 0.4 0.091 12.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) ODV-E18 PF10717.9 RJW65062.1 - 0.31 10.9 5.1 0.47 10.4 4.9 1.5 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 CDT1 PF08839.11 RJW65063.1 - 1.7e-48 165.2 0.0 2.8e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 RJW65063.1 - 1.6e-16 60.5 0.1 4e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain RVT_1 PF00078.27 RJW65063.1 - 8.1e-13 48.4 0.0 1.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EutC PF05985.11 RJW65063.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) Kinesin PF00225.23 RJW65065.1 - 8.8e-70 235.2 1.2 2.1e-69 234.0 1.2 1.7 1 0 0 1 1 1 1 Kinesin motor domain Flagellin_C PF00700.21 RJW65065.1 - 1 9.8 5.2 3.7 8.0 2.0 2.8 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF2381 PF09544.10 RJW65065.1 - 1.6 8.2 0.0 1.6 8.2 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2381) Kinesin_assoc PF16183.5 RJW65065.1 - 2.3 8.4 9.6 10 6.2 9.6 2.1 1 1 0 1 1 1 0 Kinesin-associated DUF4407 PF14362.6 RJW65065.1 - 5.1 6.4 23.5 2.5 7.4 9.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) 7tm_1 PF00001.21 RJW65069.1 - 3.3e-71 239.7 12.7 4.2e-71 239.4 12.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW65069.1 - 1.6e-09 37.8 13.5 1.6e-09 37.8 13.5 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RJW65069.1 - 5.1e-05 23.1 13.5 0.00022 21.1 10.9 2.1 2 0 0 2 2 2 1 Olfactory receptor RRM_1 PF00076.22 RJW65071.1 - 1.7e-36 123.9 0.0 4.3e-17 61.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RJW65071.1 - 0.016 15.1 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 RJW65071.1 - 0.024 14.9 0.3 3.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 RJW65071.1 - 0.14 12.2 0.0 2.7 8.1 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif FERM_M PF00373.18 RJW65072.1 - 7.5e-09 36.0 0.0 1.7e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 RJW65072.1 - 7.6e-09 35.8 0.1 1.6e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DENN PF02141.21 RJW65073.1 - 3.6e-11 43.4 0.7 8.2e-11 42.2 0.4 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 RJW65073.1 - 3.1e-05 23.9 1.1 8e-05 22.5 1.1 1.8 1 0 0 1 1 1 1 dDENN domain UBZ_FAAP20 PF15750.5 RJW65073.1 - 0.28 11.2 1.9 0.33 10.9 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger CUB PF00431.20 RJW65074.1 - 1.6e-25 89.5 0.2 3e-25 88.7 0.2 1.4 1 0 0 1 1 1 1 CUB domain 7tm_2 PF00002.24 RJW65076.1 - 1.1e-32 113.3 8.8 6.9e-28 97.6 7.3 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) CBS PF00571.28 RJW65077.1 - 2.1e-05 24.9 0.0 0.61 10.6 0.0 4.2 4 0 0 4 4 4 2 CBS domain RRM_1 PF00076.22 RJW65078.1 - 2e-16 59.6 0.0 3.2e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RJW65078.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 RJW65078.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated HRM PF02793.22 RJW65082.1 - 0.00034 20.9 0.7 0.00034 20.9 0.7 1.8 2 0 0 2 2 2 1 Hormone receptor domain MukB_hinge PF16330.5 RJW65082.1 - 0.046 13.4 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 MukB hinge domain Lamp PF01299.17 RJW65083.1 - 2.4e-09 37.2 0.2 3.6e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) SKG6 PF08693.10 RJW65083.1 - 0.00068 19.0 0.5 0.0014 18.0 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ATP-synt_S1 PF05827.12 RJW65083.1 - 0.0011 18.9 0.1 0.0021 17.9 0.1 1.5 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Adeno_E3_CR2 PF02439.15 RJW65083.1 - 0.017 14.9 0.9 0.028 14.2 0.9 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 stn_TNFRSF12A PF12191.8 RJW65083.1 - 0.031 14.5 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Orf78 PF06024.12 RJW65083.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Orf78 (ac78) Frag1 PF10277.9 RJW65083.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF4448 PF14610.6 RJW65083.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Chordopox_A13L PF05961.11 RJW65083.1 - 0.11 12.8 0.6 0.3 11.3 0.6 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein PAN_1 PF00024.26 RJW65084.1 - 0.00018 21.4 2.4 0.00051 20.0 0.7 2.2 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.12 RJW65084.1 - 0.034 13.9 5.1 0.2 11.5 1.1 2.5 2 0 0 2 2 2 0 PAN-like domain AAA PF00004.29 RJW65085.1 - 8.7e-44 149.1 0.0 2e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW65085.1 - 1.8e-10 40.5 0.1 3.4e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 RJW65085.1 - 6e-08 32.5 0.0 1.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 RJW65085.1 - 9.1e-07 29.4 0.0 0.0003 21.2 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RJW65085.1 - 7.4e-06 26.3 0.2 0.0021 18.3 0.0 2.9 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.14 RJW65085.1 - 1.6e-05 25.1 0.0 7.4e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 RJW65085.1 - 2.7e-05 23.9 0.0 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RJW65085.1 - 3.1e-05 24.0 0.1 0.00048 20.1 0.1 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RJW65085.1 - 0.00088 19.4 0.0 0.0061 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RJW65085.1 - 0.004 16.7 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 RJW65085.1 - 0.0041 17.7 0.0 0.013 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 RJW65085.1 - 0.0055 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 RJW65085.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RJW65085.1 - 0.0061 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 RJW65085.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 RJW65085.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 RJW65085.1 - 0.017 15.2 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 RJW65085.1 - 0.022 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 RJW65085.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 RJW65085.1 - 0.039 13.6 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_24 PF13479.6 RJW65085.1 - 0.088 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3924 PF13062.6 RJW65085.1 - 0.09 12.7 0.1 0.32 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) AAA_11 PF13086.6 RJW65085.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RJW65085.1 - 0.11 12.3 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 RJW65085.1 - 0.16 11.9 0.0 1 9.3 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 RJW65085.1 - 0.17 11.2 0.0 0.99 8.7 0.0 2.2 3 0 0 3 3 3 0 KaiC G-patch PF01585.23 RJW65086.1 - 1.5e-07 31.2 0.0 4.1e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 G-patch domain zf-CCCH PF00642.24 RJW65086.1 - 0.0014 18.5 4.1 0.0034 17.3 4.1 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF5538 PF17692.1 RJW65092.1 - 0.0015 18.6 0.2 2.4 8.3 0.1 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5538) FBD PF08387.10 RJW65092.1 - 0.075 12.9 2.0 13 5.8 0.1 2.9 3 0 0 3 3 3 0 FBD SOUL PF04832.12 RJW65093.1 - 1e-13 51.8 0.0 1.2e-13 51.6 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein DUF4121 PF13497.6 RJW65093.1 - 0.12 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) YugN PF08868.10 RJW65094.1 - 1.8 8.5 10.2 4.2 7.3 0.8 2.5 3 0 0 3 3 3 0 YugN-like family Actin PF00022.19 RJW65095.1 - 2.7e-151 503.8 0.0 8.7e-151 502.1 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 RJW65096.1 - 4.1e-149 496.6 0.0 1.1e-148 495.2 0.0 1.6 1 1 0 1 1 1 1 Actin NTP_transf_7 PF07984.12 RJW65098.1 - 4.9e-05 22.7 1.0 7.8e-05 22.1 1.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase ARL2_Bind_BART PF11527.8 RJW65099.1 - 9.3e-11 41.9 0.6 1.2e-10 41.5 0.6 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART RPAP2_Rtr1 PF04181.13 RJW65100.1 - 5.9e-20 71.4 0.6 1.6e-19 70.0 0.6 1.8 1 0 0 1 1 1 1 Rtr1/RPAP2 family DnaJ PF00226.31 RJW65100.1 - 2.6e-10 40.3 0.0 5.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-CCCH PF00642.24 RJW65100.1 - 1.2e-09 37.8 2.1 3.9e-09 36.2 2.1 2.0 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 RJW65100.1 - 8.6e-08 31.9 7.0 2.8e-07 30.3 7.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW65100.1 - 1.4e-06 28.0 9.0 4.7e-06 26.4 9.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW65100.1 - 3.1e-06 27.1 5.5 1e-05 25.4 5.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 RJW65100.1 - 4.5e-06 26.5 3.5 1.3e-05 25.1 3.5 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-RING_5 PF14634.6 RJW65100.1 - 9.9e-06 25.4 10.1 9.9e-06 25.4 10.1 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RJW65100.1 - 2.1e-05 24.3 9.4 6.3e-05 22.8 9.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 RJW65100.1 - 0.00015 21.4 1.9 0.00015 21.4 1.9 2.7 2 0 0 2 2 2 1 CCCH-type zinc finger zf-RING_2 PF13639.6 RJW65100.1 - 0.00024 21.4 7.9 0.00024 21.4 7.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.5 RJW65100.1 - 0.00044 20.3 5.3 0.0015 18.6 5.3 1.9 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 RJW65100.1 - 0.0028 17.5 4.5 0.0028 17.5 4.5 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-CSL PF05207.13 RJW65100.1 - 0.013 15.3 2.5 0.013 15.3 2.5 2.2 2 0 0 2 2 2 0 CSL zinc finger zf-Nse PF11789.8 RJW65100.1 - 0.068 13.0 3.9 0.22 11.4 3.9 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_2 PF14608.6 RJW65100.1 - 0.11 13.1 2.2 0.35 11.4 2.2 2.0 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CobT PF06213.12 RJW65100.1 - 0.17 11.2 0.8 0.35 10.2 0.1 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DnaB_2 PF07261.11 RJW65102.1 - 6.9e-33 112.2 0.0 5.8 6.7 0.0 17.9 1 1 21 22 22 22 21 Replication initiation and membrane attachment THP2 PF09432.10 RJW65102.1 - 5.8e-08 32.9 120.5 1 9.4 1.2 17.7 1 1 19 21 21 21 21 Tho complex subunit THP2 PT PF04886.12 RJW65102.1 - 7.9e-07 28.5 156.1 1.4 8.6 0.1 23.3 23 0 0 23 23 23 23 PT repeat MIF4G PF02854.19 RJW65102.1 - 2e-06 27.6 87.4 3.4 7.2 1.2 13.0 1 1 17 18 18 18 17 MIF4G domain Alkyl_sulf_dimr PF14863.6 RJW65102.1 - 0.00027 21.4 60.1 20 5.6 0.2 15.9 1 1 20 21 21 21 1 Alkyl sulfatase dimerisation LCM PF04072.14 RJW65103.1 - 3.3e-23 82.6 0.0 1.5e-22 80.5 0.0 2.0 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase TP6A_N PF04406.14 RJW65104.1 - 2.7 8.1 26.7 1.4e+02 2.6 0.0 9.2 9 0 0 9 9 9 0 Type IIB DNA topoisomerase Gly_radical PF01228.21 RJW65105.1 - 0.023 15.3 1.0 0.082 13.5 0.0 2.2 2 1 0 2 2 2 0 Glycine radical Cnd1 PF12717.7 RJW65105.1 - 0.037 14.1 0.8 0.084 12.9 0.3 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Actin PF00022.19 RJW65107.1 - 2.5e-149 497.4 0.0 6.5e-149 496.0 0.0 1.6 1 1 0 1 1 1 1 Actin NTP_transf_7 PF07984.12 RJW65108.1 - 1e-20 74.3 0.0 3.8e-20 72.3 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase Sulfotransfer_4 PF17784.1 RJW65109.1 - 1.1e-60 205.2 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW65109.1 - 0.0098 16.3 0.0 3.9 7.8 0.0 2.5 1 1 0 2 2 2 2 Sulfotransferase family EF-hand_1 PF00036.32 RJW65110.1 - 3.3e-22 76.3 1.9 8.9e-06 24.9 0.0 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 RJW65110.1 - 3.9e-22 78.5 0.9 1.2e-09 38.4 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW65110.1 - 3.2e-21 73.4 0.8 6.5e-06 25.7 0.0 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 RJW65110.1 - 7.6e-15 53.7 1.4 0.00013 21.3 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RJW65110.1 - 2.6e-14 52.8 0.3 1.4e-08 34.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair Scytalone_dh PF02982.14 RJW65110.1 - 0.034 14.0 0.1 0.095 12.5 0.1 1.7 1 0 0 1 1 1 0 Scytalone dehydratase Transketolase_C PF02780.20 RJW65111.1 - 1.4e-36 125.1 0.0 2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 RJW65111.1 - 1.1e-34 119.7 0.0 1.8e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain CIDE-N PF02017.15 RJW65114.1 - 0.096 12.7 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 CIDE-N domain PNISR PF15996.5 RJW65115.1 - 0.0067 16.7 6.4 0.0067 16.7 6.4 2.8 3 0 0 3 3 3 1 Arginine/serine-rich protein PNISR RVT_1 PF00078.27 RJW65116.1 - 1.1e-08 34.8 0.0 2.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SdrD_B PF17210.3 RJW65118.1 - 0.091 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 SdrD B-like domain Ank_2 PF12796.7 RJW65119.1 - 9e-16 58.2 2.7 0.00013 22.5 0.0 8.3 8 1 1 9 9 9 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW65119.1 - 1e-15 57.6 10.9 0.00014 22.0 0.1 8.1 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW65119.1 - 9.5e-08 32.4 9.4 0.48 11.1 0.0 8.2 8 1 1 9 9 9 2 Ankyrin repeats (many copies) Ank PF00023.30 RJW65119.1 - 8e-06 26.1 8.0 1.5 9.4 0.1 7.4 7 0 0 7 7 7 1 Ankyrin repeat Ank_3 PF13606.6 RJW65119.1 - 9.3e-05 22.6 13.7 19 6.3 0.1 10.1 11 0 0 11 11 11 1 Ankyrin repeat IMS PF00817.20 RJW65120.1 - 4.1e-38 130.7 0.0 8e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 RJW65120.1 - 5.9e-11 43.1 0.3 7.2e-10 39.6 0.1 2.7 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 RJW65120.1 - 6.2e-11 42.6 0.0 1.4e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain REV1_C PF16727.5 RJW65120.1 - 1.4e-10 41.4 0.0 3.6e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain BRCT PF00533.26 RJW65120.1 - 7.5e-06 26.2 0.0 2.8e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 RJW65120.1 - 1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 RJW65120.1 - 0.00013 21.9 0.0 0.00031 20.6 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 RJW65120.1 - 0.0002 21.5 0.2 0.003 17.8 0.0 2.8 3 0 0 3 3 3 1 IMS family HHH motif HMG_box PF00505.19 RJW65122.1 - 1.4e-25 89.5 3.8 3.1e-25 88.4 3.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW65122.1 - 2.3e-10 40.9 2.8 2.6e-10 40.8 1.4 1.9 2 0 0 2 2 2 1 HMG-box domain Sulfotransfer_3 PF13469.6 RJW65123.1 - 5.4e-34 118.5 0.0 1e-33 117.6 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RJW65123.1 - 2.4e-07 30.5 0.0 5.2e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Glyco_hydro_38N PF01074.22 RJW65124.1 - 2.6e-85 286.3 1.2 3.3e-85 285.9 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 RJW65124.1 - 7.2e-24 83.8 0.1 3.9e-23 81.4 0.1 2.1 2 0 0 2 2 2 1 Alpha mannosidase middle domain Bestrophin PF01062.21 RJW65125.1 - 0.058 12.8 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel CSD PF00313.22 RJW65129.1 - 7.7e-17 60.9 0.0 1.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Sulfotransfer_3 PF13469.6 RJW65130.1 - 1.8e-26 93.9 0.0 2.4e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RJW65130.1 - 3.6e-06 26.7 0.0 6.8e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain DUF4735 PF15882.5 RJW65131.1 - 0.073 12.5 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) PAN_1 PF00024.26 RJW65132.1 - 2.4e-05 24.2 0.8 2.4e-05 24.2 0.8 1.1 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 RJW65132.1 - 0.0068 16.5 0.6 0.0088 16.1 0.6 1.2 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 RJW65132.1 - 0.013 15.3 1.3 0.022 14.6 1.3 1.4 1 1 0 1 1 1 0 PAN domain EcoEI_R_C PF08463.10 RJW65134.1 - 0.05 13.7 0.4 0.13 12.4 0.4 1.7 1 0 0 1 1 1 0 EcoEI R protein C-terminal MNE1 PF13762.6 RJW65134.1 - 0.14 12.2 0.2 4.4 7.3 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component DUF3826 PF12875.7 RJW65134.1 - 0.14 12.3 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) RVT_1 PF00078.27 RJW65137.1 - 0.0012 18.5 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 RJW65137.1 - 0.012 16.0 1.6 0.012 16.0 1.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 RJW65137.1 - 0.033 14.6 0.8 0.13 12.7 0.8 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 RJW65137.1 - 0.4 11.7 4.7 0.61 11.1 1.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger PUF PF00806.19 RJW65138.1 - 7.5e-33 110.4 0.6 8.8e-08 31.4 0.0 4.5 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat Peptidase_M3 PF01432.20 RJW65139.1 - 4.1e-70 237.3 0.0 5.8e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 E1_DerP2_DerF2 PF02221.15 RJW65140.1 - 4.4e-22 79.0 0.1 5.2e-22 78.7 0.1 1.0 1 0 0 1 1 1 1 ML domain Cu-oxidase_3 PF07732.15 RJW65140.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.6 1 1 0 1 1 1 0 Multicopper oxidase Band_7 PF01145.25 RJW65141.1 - 0.00034 20.7 0.1 0.00068 19.7 0.0 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family GST_C_3 PF14497.6 RJW65142.1 - 6.3e-09 35.9 0.0 9.2e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RJW65142.1 - 2.6e-08 34.0 0.0 5.1e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RJW65142.1 - 2.6e-07 30.9 0.0 6.6e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RJW65142.1 - 7.8e-07 29.0 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RJW65142.1 - 0.057 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Na_K-ATPase PF00287.18 RJW65143.1 - 3.6e-45 154.3 4.9 8.2e-45 153.2 4.9 1.5 1 1 0 1 1 1 1 Sodium / potassium ATPase beta chain Glyco_transf_6 PF03414.13 RJW65144.1 - 0.021 13.6 0.1 0.039 12.7 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 6 PRANC PF09372.10 RJW65144.1 - 0.042 14.2 0.5 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 PRANC domain GDA1_CD39 PF01150.17 RJW65145.1 - 3.6e-65 220.3 0.0 1.1e-63 215.5 0.0 2.4 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family WD40 PF00400.32 RJW65147.1 - 4.7e-20 71.5 6.7 0.00034 21.3 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW65147.1 - 2.1e-05 24.8 0.2 13 6.2 0.0 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain CAMSAP_CC1 PF17095.5 RJW65147.1 - 0.074 12.9 1.8 0.14 12.0 1.8 1.4 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin T-box_assoc PF16176.5 RJW65150.1 - 0.0074 16.4 2.0 0.24 11.5 0.6 2.3 1 1 2 3 3 3 3 T-box transcription factor-associated DUF1330 PF07045.11 RJW65151.1 - 1.2e-06 28.7 0.0 0.017 15.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) KapB PF08810.10 RJW65151.1 - 0.042 14.0 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase associated protein B RVT_1 PF00078.27 RJW65152.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C PF00271.31 RJW65152.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain XRN_N PF03159.18 RJW65154.1 - 7.4e-103 343.2 0.0 8.5e-103 343.0 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Thymopoietin PF08198.11 RJW65154.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Thymopoietin protein zf-CCHC_4 PF14392.6 RJW65154.1 - 0.15 11.8 0.1 0.41 10.4 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle V-set PF07686.17 RJW65156.1 - 9.7e-23 80.4 15.9 0.0033 17.6 0.4 11.9 10 0 0 10 10 10 7 Immunoglobulin V-set domain I-set PF07679.16 RJW65156.1 - 1.8e-08 34.3 3.1 2.1 8.4 0.1 8.3 10 0 0 10 10 10 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW65156.1 - 7.7e-07 29.6 13.8 1 10.0 0.0 9.8 10 0 0 10 10 10 3 Immunoglobulin domain Cyclin_N PF00134.23 RJW65158.1 - 2.2e-13 50.1 0.8 1.5e-11 44.1 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RJW65158.1 - 0.00047 20.2 0.7 0.0019 18.3 0.1 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 RJW65158.1 - 0.00091 19.2 0.6 1.1 9.4 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 RJW65158.1 - 0.15 12.4 0.1 0.54 10.7 0.0 1.9 2 0 0 2 2 2 0 Cyclin C-terminal domain KTSC PF13619.6 RJW65160.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 KTSC domain Atypical_Card PF18461.1 RJW65162.1 - 0.14 12.3 0.3 2 8.7 0.0 2.7 2 1 1 3 3 3 0 Atypical caspase recruitment domain Peptidase_C14 PF00656.22 RJW65164.1 - 2.9e-38 132.3 0.0 4.4e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 RJW65164.1 - 8.5e-10 38.5 0.1 1.9e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 RJW65164.1 - 0.0023 17.9 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain Transferrin PF00405.17 RJW65164.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Transferrin GCFC PF07842.12 RJW65168.1 - 6.7e-60 203.0 14.7 1.1e-59 202.4 14.7 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Peptidase_C54 PF03416.19 RJW65170.1 - 2.9e-48 164.7 0.0 4.2e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 RVT_1 PF00078.27 RJW65170.1 - 0.038 13.5 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PhoLip_ATPase_C PF16212.5 RJW65174.1 - 6.2e-55 186.7 19.4 8.3e-55 186.2 19.4 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase_3 PF08282.12 RJW65174.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RGS PF00615.19 RJW65174.1 - 0.041 14.1 1.2 0.28 11.5 0.2 2.4 2 0 0 2 2 2 0 Regulator of G protein signaling domain Hydrolase PF00702.26 RJW65174.1 - 0.05 13.9 0.1 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Branch PF02485.21 RJW65177.1 - 1.7e-27 96.6 0.0 2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Folliculin PF11704.8 RJW65179.1 - 5e-34 117.8 0.0 8.1e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport PhoLip_ATPase_C PF16212.5 RJW65180.1 - 1.8e-50 172.0 22.4 1.8e-50 172.0 22.4 3.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RJW65180.1 - 1.2e-12 47.3 3.0 4e-12 45.6 3.0 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RJW65180.1 - 1.7e-11 44.9 4.1 5.9e-08 33.3 1.6 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RJW65180.1 - 1.8e-05 24.7 0.1 0.0002 21.3 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RJW65180.1 - 0.0013 18.3 0.0 0.007 15.9 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Neur_chan_memb PF02932.16 RJW65181.1 - 1.6 8.7 7.7 2.5 8.1 7.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAT1 PF06391.13 RJW65181.1 - 4.1 7.2 24.6 9.1 6.1 24.6 1.6 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 RR_TM4-6 PF06459.12 RJW65181.1 - 7.2 6.3 13.6 11 5.7 13.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAN_1 PF00024.26 RJW65183.1 - 0.0028 17.6 1.3 0.0028 17.6 1.3 2.0 2 0 0 2 2 2 1 PAN domain RVT_1 PF00078.27 RJW65188.1 - 5.7e-47 160.1 0.5 3.6e-46 157.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW65188.1 - 0.0022 17.8 0.0 0.019 14.8 0.0 2.5 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase LisH_TPL PF17814.1 RJW65188.1 - 0.012 15.2 0.1 0.033 13.9 0.1 1.7 1 0 0 1 1 1 0 LisH-like dimerisation domain Ras PF00071.22 RJW65189.1 - 9e-47 158.7 0.1 1.4e-46 158.1 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW65189.1 - 2.6e-26 92.2 0.0 4.8e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW65189.1 - 1.2e-09 37.9 0.2 1.8e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF229 PF02995.17 RJW65192.1 - 7.1e-37 127.2 0.0 8.6e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF229 PF02995.17 RJW65193.1 - 7.3e-52 176.6 0.0 9.9e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphorylase PF00343.20 RJW65194.1 - 4.6e-272 904.5 0.0 5.4e-272 904.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase KH_6 PF15985.5 RJW65196.1 - 6.5e-12 45.6 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 KH domain NUDIX PF00293.28 RJW65198.1 - 4.9e-11 42.8 0.0 8.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF1962 PF09227.10 RJW65198.1 - 1.4 9.4 3.9 5 7.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1962) Folliculin_C PF16692.5 RJW65199.1 - 1.5e-44 152.4 0.0 2e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Folliculin C-terminal domain Pkinase PF00069.25 RJW65200.1 - 9.2e-61 205.5 0.0 1.3e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW65200.1 - 7.3e-28 97.5 0.0 1.1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW65200.1 - 0.0013 17.6 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW65200.1 - 0.013 14.9 0.0 0.087 12.1 0.0 2.2 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 RJW65200.1 - 0.021 14.8 0.0 0.051 13.5 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family HSP90 PF00183.18 RJW65202.1 - 1.3e-229 763.4 24.2 1.7e-229 763.1 24.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 RJW65202.1 - 7.3e-14 52.2 0.1 1.4e-13 51.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RJW65202.1 - 1.6e-09 37.7 0.1 4.2e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 RJW65202.1 - 0.059 13.4 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Tumour suppressor protein Clathrin_lg_ch PF01086.17 RJW65203.1 - 3.2e-11 43.7 9.9 5e-09 36.6 3.9 2.4 2 1 1 3 3 3 2 Clathrin light chain Dus PF01207.17 RJW65204.1 - 1.7e-51 175.2 0.1 3.6e-51 174.1 0.1 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) dsrm PF00035.26 RJW65204.1 - 1.8e-06 28.5 0.1 3.3e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif NMO PF03060.15 RJW65204.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 RJW65204.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein LSM PF01423.22 RJW65205.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 LSM domain DGCR6 PF07324.11 RJW65206.1 - 1e-39 136.2 5.0 1.3e-39 135.8 5.0 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Trp_syntA PF00290.20 RJW65206.1 - 0.044 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Phosducin PF02114.16 RJW65206.1 - 0.067 12.1 1.5 0.085 11.8 1.5 1.2 1 0 0 1 1 1 0 Phosducin NPA PF16469.5 RJW65206.1 - 0.19 12.3 1.9 1.2 9.7 0.1 2.1 1 1 1 2 2 2 0 Nematode polyprotein allergen ABA-1 Peptidase_C1 PF00112.23 RJW65207.1 - 5.8e-61 206.3 0.0 8.1e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW65207.1 - 1.7e-11 44.4 1.1 2.8e-11 43.7 1.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW65207.1 - 0.0012 17.7 0.9 0.16 10.7 0.1 2.6 2 1 1 3 3 3 2 Peptidase C1-like family zf-C2H2 PF00096.26 RJW65208.1 - 6.3e-15 54.7 50.1 0.00024 21.4 3.4 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW65208.1 - 1.5e-11 44.2 44.9 3.6e-06 27.2 0.3 7.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW65208.1 - 2e-09 37.4 44.9 0.064 14.1 1.8 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RJW65208.1 - 3.9e-07 30.3 21.4 5e-05 23.5 6.5 3.9 1 1 1 3 3 3 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 RJW65208.1 - 5.8e-05 23.6 18.7 2.6 8.7 0.0 6.0 5 1 1 6 6 6 4 FOXP coiled-coil domain zf-met PF12874.7 RJW65208.1 - 0.11 13.0 18.3 1.1 9.7 0.5 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 RJW65210.1 - 8.8e-21 73.1 54.3 0.0095 16.4 0.7 8.5 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW65210.1 - 1.6e-17 63.0 52.7 1.4e-05 25.3 0.9 8.9 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW65210.1 - 5.4e-11 42.4 49.2 0.036 14.9 0.5 8.6 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RJW65210.1 - 1.2e-06 28.7 10.2 0.028 14.6 0.0 4.2 3 1 1 4 4 4 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 RJW65210.1 - 4e-06 27.0 16.2 0.027 14.8 1.1 4.6 3 1 0 4 4 4 3 C2H2-type zinc ribbon GAGA PF09237.11 RJW65210.1 - 0.00035 20.3 3.6 0.089 12.6 0.1 3.2 3 0 0 3 3 3 2 GAGA factor IBR PF01485.21 RJW65210.1 - 0.0022 18.2 27.0 0.77 10.0 1.9 5.5 3 2 0 4 4 4 3 IBR domain, a half RING-finger domain zf_CopZ PF18423.1 RJW65210.1 - 0.022 14.7 14.8 0.77 9.8 0.1 5.5 2 2 4 6 6 6 0 Zinc binding domain Ogr_Delta PF04606.12 RJW65210.1 - 0.064 13.2 17.3 0.41 10.7 2.5 4.8 4 1 0 4 4 4 0 Ogr/Delta-like zinc finger zf-C2HE PF16278.5 RJW65210.1 - 0.14 12.6 13.8 1.5 9.3 0.2 4.5 4 1 1 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 RJW65210.1 - 0.17 11.9 0.1 0.17 11.9 0.1 5.1 5 0 0 5 5 4 0 C2H2-type zinc finger zf_ZIC PF18366.1 RJW65210.1 - 0.46 10.6 6.9 40 4.4 0.2 4.6 3 1 1 4 4 4 0 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 RJW65210.1 - 3.5 8.0 17.0 3.1 8.2 0.3 5.7 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 RJW65210.1 - 4.9 7.8 25.9 1.2 9.8 0.1 6.0 5 2 1 6 6 6 0 FOXP coiled-coil domain JmjC PF02373.22 RJW65211.1 - 1.2e-28 99.9 2.0 3.1e-28 98.5 1.1 2.3 3 0 0 3 3 2 1 JmjC domain, hydroxylase TPR_1 PF00515.28 RJW65211.1 - 1.8e-23 81.3 14.8 7e-07 28.8 1.5 6.6 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 RJW65211.1 - 5.8e-15 54.1 18.1 3.7e-05 23.5 0.7 6.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 RJW65211.1 - 4.4e-12 45.7 1.3 0.44 11.5 0.2 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 RJW65211.1 - 1.9e-10 40.2 6.7 0.031 14.0 1.0 5.8 3 2 2 5 5 5 3 TPR repeat TPR_8 PF13181.6 RJW65211.1 - 1.2e-09 37.6 11.0 5.2e-05 23.1 0.8 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW65211.1 - 1.3e-08 34.6 11.2 0.2 12.1 0.2 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 RJW65211.1 - 2.3e-08 34.2 16.6 0.0055 17.0 0.3 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 RJW65211.1 - 1.9e-06 28.3 8.8 0.013 16.0 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW65211.1 - 1.9e-05 24.3 9.2 0.0018 18.1 0.2 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW65211.1 - 0.00061 20.4 7.7 0.24 12.1 0.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 RJW65211.1 - 0.00075 19.3 2.1 2.1 8.3 0.1 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RJW65211.1 - 0.0025 18.3 6.1 4.7 8.1 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW65211.1 - 0.0033 17.6 11.2 0.016 15.4 0.1 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RJW65211.1 - 0.04 14.0 4.8 0.072 13.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 RJW65211.1 - 0.043 13.9 0.7 0.52 10.4 0.4 2.7 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain Kazal_2 PF07648.15 RJW65212.1 - 1.8e-12 47.2 33.3 4.4e-07 29.9 0.3 4.9 5 0 0 5 5 5 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RJW65212.1 - 4.7e-08 32.9 24.1 2.9e-05 24.0 0.5 4.8 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain FOLN PF09289.10 RJW65212.1 - 1.7e-06 28.1 11.0 3.5e-05 23.9 3.9 3.1 2 0 0 2 2 2 2 Follistatin/Osteonectin-like EGF domain cNMP_binding PF00027.29 RJW65213.1 - 3.3e-37 126.5 0.0 7.2e-18 64.5 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain FAM76 PF16046.5 RJW65213.1 - 0.054 12.8 7.3 0.054 12.9 6.1 1.5 1 1 0 1 1 1 0 FAM76 protein SlyX PF04102.12 RJW65213.1 - 0.066 13.8 0.4 0.2 12.3 0.4 1.8 1 0 0 1 1 1 0 SlyX NUMOD4 PF07463.11 RJW65213.1 - 0.13 12.4 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 NUMOD4 motif DivIC PF04977.15 RJW65213.1 - 0.27 11.0 1.6 0.77 9.6 1.6 1.7 1 0 0 1 1 1 0 Septum formation initiator Cys_rich_FGFR PF00839.17 RJW65214.1 - 1.9e-98 322.6 69.3 3.1e-14 52.9 0.2 12.4 12 1 0 12 12 12 12 Cysteine rich repeat Pkinase_Tyr PF07714.17 RJW65215.1 - 1.4e-85 286.7 0.0 2.2e-85 286.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW65215.1 - 8.4e-44 149.9 0.0 1.4e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RJW65215.1 - 1.1e-35 121.6 2.2 7.9e-18 64.3 0.1 2.5 2 0 0 2 2 2 2 SH2 domain Haspin_kinase PF12330.8 RJW65215.1 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain AAA PF00004.29 RJW65216.1 - 9.9e-44 149.0 0.1 2.7e-43 147.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW65216.1 - 4e-10 39.3 0.1 8.8e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 RJW65216.1 - 1.3e-09 37.9 0.1 7.1e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 RJW65216.1 - 2.1e-08 34.5 0.0 4.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RJW65216.1 - 1.4e-07 31.6 0.1 5.2e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RJW65216.1 - 2.8e-05 24.6 0.2 0.0061 17.0 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain DUF815 PF05673.13 RJW65216.1 - 0.00011 21.5 0.1 0.00026 20.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 RJW65216.1 - 0.00016 21.5 0.0 0.00066 19.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RJW65216.1 - 0.00042 20.6 1.7 0.052 13.8 0.0 2.8 2 1 1 3 3 2 1 AAA domain Mg_chelatase PF01078.21 RJW65216.1 - 0.00077 18.9 0.1 0.0017 17.8 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 RJW65216.1 - 0.00084 19.4 0.1 0.0063 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RJW65216.1 - 0.00092 19.6 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 RJW65216.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RJW65216.1 - 0.0011 19.1 0.0 0.0033 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 RJW65216.1 - 0.0013 18.3 0.0 0.0065 16.1 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 RJW65216.1 - 0.002 17.9 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_1 PF03266.15 RJW65216.1 - 0.0034 17.3 0.1 0.14 12.0 0.0 2.9 3 0 0 3 3 3 1 NTPase AAA_18 PF13238.6 RJW65216.1 - 0.0035 17.9 0.0 0.012 16.2 0.0 1.9 3 0 0 3 3 1 1 AAA domain TIP49 PF06068.13 RJW65216.1 - 0.0074 15.5 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 RJW65216.1 - 0.01 15.5 0.1 0.82 9.4 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 RJW65216.1 - 0.015 15.2 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 RJW65216.1 - 0.03 14.3 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 RJW65216.1 - 0.044 13.3 0.1 0.28 10.7 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 RJW65216.1 - 0.056 13.0 2.0 0.25 10.9 0.2 2.5 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 RJW65216.1 - 0.071 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 RJW65216.1 - 0.084 12.8 0.8 0.6 10.0 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 RJW65216.1 - 0.084 12.3 0.0 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 RJW65216.1 - 0.092 13.3 0.0 0.33 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_3 PF07726.11 RJW65216.1 - 0.095 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_C1 PF00112.23 RJW65218.1 - 5.1e-58 196.7 0.1 7.1e-58 196.3 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW65218.1 - 1.6e-11 44.4 1.1 2.6e-11 43.8 1.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW65218.1 - 0.00054 18.9 0.7 0.077 11.8 0.1 2.6 2 1 1 3 3 3 2 Peptidase C1-like family CSTF_C PF14304.6 RJW65220.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Pou PF00157.17 RJW65225.1 - 1.9e-36 123.9 0.1 3.8e-36 122.9 0.1 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 RJW65225.1 - 5.4e-17 61.4 0.5 5.4e-17 61.4 0.5 2.0 2 0 0 2 2 2 1 Homeodomain RhlB PF12300.8 RJW65225.1 - 0.024 14.8 0.6 0.065 13.4 0.1 1.9 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Hom_end PF05204.14 RJW65225.1 - 0.33 11.1 0.9 23 5.2 0.0 3.3 3 0 0 3 3 3 0 Homing endonuclease WD40 PF00400.32 RJW65226.1 - 2e-16 60.1 5.2 8.2e-05 23.3 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW65226.1 - 0.0028 17.9 0.0 1.5 9.2 0.0 3.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cu2_monoox_C PF03712.15 RJW65228.1 - 3.9e-60 201.9 0.0 1.3e-59 200.2 0.0 1.9 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 RJW65228.1 - 2.8e-42 144.1 0.1 6e-42 143.0 0.1 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Glycos_transf_3 PF00591.21 RJW65228.1 - 0.065 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family, a/b domain DOMON PF03351.17 RJW65228.1 - 0.08 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 DOMON domain 7TM_GPCR_Srw PF10324.9 RJW65229.1 - 6.1e-10 38.9 10.1 9.4e-10 38.3 8.1 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RJW65229.1 - 1.7e-06 27.6 7.0 2.3e-06 27.2 7.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4446 PF14584.6 RJW65229.1 - 0.4 10.7 0.1 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CitMHS PF03600.16 RJW65229.1 - 0.62 9.2 8.1 0.84 8.8 8.1 1.3 1 1 0 1 1 1 0 Citrate transporter TMEM154 PF15102.6 RJW65229.1 - 1 9.2 8.6 0.14 12.1 1.8 2.5 1 1 0 2 2 2 0 TMEM154 protein family Baculo_11_kDa PF06143.11 RJW65229.1 - 8.3 6.1 8.8 0.33 10.5 0.3 2.9 3 1 0 3 3 3 0 Baculovirus 11 kDa family Pkinase_Tyr PF07714.17 RJW65230.1 - 1e-71 241.3 0.0 1.5e-71 240.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW65230.1 - 4.4e-43 147.5 0.0 6.8e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 RJW65230.1 - 3.2e-20 72.5 0.7 7e-20 71.4 0.3 1.7 2 0 0 2 2 2 1 Receptor family ligand binding region Kinase-like PF14531.6 RJW65230.1 - 0.0028 17.0 0.0 0.0067 15.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RNB PF00773.19 RJW65230.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 RNB domain I-set PF07679.16 RJW65232.1 - 0 1215.3 0.0 1.6e-16 60.2 0.0 28.3 28 0 0 28 28 28 28 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW65232.1 - 0 1149.2 30.5 4.6e-17 62.4 0.0 28.4 28 0 0 28 28 28 28 Immunoglobulin domain Ig_2 PF13895.6 RJW65232.1 - 2.4e-248 803.3 8.5 7.9e-11 42.1 0.0 28.7 27 1 1 28 28 28 28 Immunoglobulin domain ig PF00047.25 RJW65232.1 - 6.1e-213 689.7 1.1 1.3e-10 41.3 0.0 28.9 28 1 0 28 28 28 26 Immunoglobulin domain V-set PF07686.17 RJW65232.1 - 2.9e-93 307.4 30.6 1.6e-05 25.1 0.0 35.5 26 11 4 30 30 30 20 Immunoglobulin V-set domain C2-set_2 PF08205.12 RJW65232.1 - 3.4e-69 228.9 37.5 0.0086 16.1 0.0 26.1 26 0 0 26 26 26 17 CD80-like C2-set immunoglobulin domain TSP_1 PF00090.19 RJW65232.1 - 2e-42 143.2 70.0 3.6e-11 43.1 7.9 6.5 5 1 0 5 5 5 4 Thrombospondin type 1 domain Ig_6 PF18452.1 RJW65232.1 - 2.3e-42 142.3 0.0 0.0039 16.7 0.0 22.5 25 0 0 25 25 25 8 Immunoglobulin domain Izumo-Ig PF16706.5 RJW65232.1 - 2.8e-30 104.2 3.3 0.13 12.4 0.0 19.8 22 0 0 22 22 22 4 Izumo-like Immunoglobulin domain C1-set PF07654.15 RJW65232.1 - 4.5e-21 75.0 2.4 11 6.5 0.0 17.3 20 0 0 20 20 17 0 Immunoglobulin C1-set domain Adeno_E3_CR1 PF02440.15 RJW65232.1 - 3.8e-18 65.0 1.8 0.63 9.9 0.0 15.1 16 0 0 16 16 15 2 Adenovirus E3 region protein CR1 EGF_CA PF07645.15 RJW65232.1 - 4e-17 62.1 47.8 7.4e-07 29.3 8.4 6.5 5 0 0 5 5 4 3 Calcium-binding EGF domain cEGF PF12662.7 RJW65232.1 - 3.9e-15 55.5 25.8 2.1e-10 40.3 2.2 5.5 5 0 0 5 5 4 4 Complement Clr-like EGF-like BiPBP_C PF06832.12 RJW65232.1 - 6.2e-15 55.0 0.0 1.7 8.7 0.0 11.8 11 1 0 11 11 10 2 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 RJW65232.1 - 5.9e-14 52.2 0.0 0.87 9.8 0.0 13.2 14 1 1 15 15 15 2 Natural killer cell receptor 2B4 C2-set PF05790.15 RJW65232.1 - 3.4e-10 40.0 0.0 62 3.9 0.0 13.7 16 0 0 16 16 15 0 Immunoglobulin C2-set domain G2F PF07474.12 RJW65232.1 - 1.7e-08 34.4 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 G2F domain FXa_inhibition PF14670.6 RJW65232.1 - 3.8e-06 27.1 10.3 3.8e-06 27.1 10.3 6.1 6 0 0 6 6 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 RJW65232.1 - 0.00011 22.5 36.0 0.13 12.6 5.6 4.9 3 0 0 3 3 3 3 EGF-like domain V-set_CD47 PF08204.11 RJW65232.1 - 0.0055 16.7 9.6 12 5.9 0.0 10.2 14 1 1 15 15 13 0 CD47 immunoglobulin-like domain PD40 PF07676.12 RJW65232.1 - 0.0057 16.6 0.3 7.6 6.6 0.0 4.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat hEGF PF12661.7 RJW65232.1 - 0.21 12.3 27.3 1.7 9.4 9.2 5.8 4 0 0 4 4 4 0 Human growth factor-like EGF Branch PF02485.21 RJW65235.1 - 6.5e-32 111.0 0.2 8.7e-32 110.6 0.2 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme SnoaL_4 PF13577.6 RJW65235.1 - 0.15 12.2 0.1 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like domain zf-C2H2 PF00096.26 RJW65236.1 - 4.2 8.0 6.0 1 10.0 1.8 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type EcoEI_R_C PF08463.10 RJW65238.1 - 1.9 8.5 12.9 2.2 8.4 0.1 3.6 3 1 0 3 3 3 0 EcoEI R protein C-terminal Voldacs PF03517.13 RJW65240.1 - 7.7e-22 77.9 0.5 1.1e-21 77.4 0.5 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Ras PF00071.22 RJW65244.1 - 3.8e-43 146.9 0.1 7.4e-43 145.9 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW65244.1 - 5.8e-22 78.2 0.0 1.6e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW65244.1 - 2.2e-08 33.8 0.1 5.1e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Exo_endo_phos_2 PF14529.6 RJW65244.1 - 0.00021 21.1 0.0 0.0005 19.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase GTP_EFTU PF00009.27 RJW65244.1 - 0.004 16.7 0.1 0.0054 16.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Exo_endo_phos PF03372.23 RJW65244.1 - 0.0058 16.2 0.1 0.0079 15.7 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AP_endonuc_2 PF01261.24 RJW65244.1 - 0.0062 16.0 0.3 1.6 8.1 0.1 3.7 2 2 1 3 3 3 1 Xylose isomerase-like TIM barrel Otopetrin PF03189.13 RJW65246.1 - 1.3e-37 129.7 14.9 4.8e-23 81.7 7.1 2.3 1 1 1 2 2 2 2 Otopetrin Acetyltransf_1 PF00583.25 RJW65247.1 - 2.6e-11 43.8 0.0 4.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RJW65247.1 - 7.1e-09 35.7 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RJW65247.1 - 2.5e-06 27.3 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 RJW65247.1 - 8.7e-06 26.1 0.0 1.7e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RJW65247.1 - 0.0011 19.0 0.3 0.035 14.2 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain MMS22L_N PF14910.6 RJW65249.1 - 1.2e-05 24.0 11.5 4e-05 22.3 11.5 1.9 1 1 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal RVT_1 PF00078.27 RJW65250.1 - 1e-05 25.2 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Molybdopterin PF00384.22 RJW65250.1 - 0.075 12.0 0.0 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Mating_N PF12731.7 RJW65250.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Mating-type protein beta 1 LIM PF00412.22 RJW65252.1 - 1.2e-25 89.4 41.4 1.2e-09 38.3 6.5 3.7 3 1 0 3 3 3 3 LIM domain tRNA-synt_1g PF09334.11 RJW65252.1 - 6.5 5.4 5.8 9.9 4.8 5.8 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Cofilin_ADF PF00241.20 RJW65254.1 - 1.5e-10 41.0 0.0 2.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Toxin_19 PF08088.12 RJW65254.1 - 0.051 13.7 1.9 0.15 12.2 1.9 1.8 1 0 0 1 1 1 0 Conotoxin I-superfamily Nup96 PF12110.8 RJW65255.1 - 1.4e-87 293.5 0.0 2e-87 293.0 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 RJW65255.1 - 9.2e-46 155.6 0.0 1.6e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 RJW65255.1 - 1.9e-10 41.4 202.0 0.00031 21.5 27.2 9.4 3 1 5 8 8 8 6 Nucleoporin FG repeat region RVT_1 PF00078.27 RJW65255.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 RJW65256.1 - 3.9e-58 196.9 0.0 5.8e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW65256.1 - 6.6e-25 87.9 0.0 1.1e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RJW65256.1 - 0.0015 17.9 0.2 0.0034 16.8 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RJW65256.1 - 0.15 11.0 0.5 0.6 9.0 0.0 2.1 3 0 0 3 3 3 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RJW65256.1 - 0.53 9.0 2.4 5 5.8 0.0 2.8 2 1 1 3 3 3 0 Fungal protein kinase Thx PF17070.5 RJW65256.1 - 0.68 10.1 2.3 22 5.4 0.9 3.0 2 0 0 2 2 2 0 30S ribosomal protein Thx PAT1 PF09770.9 RJW65256.1 - 1.6 6.9 6.8 2.2 6.5 6.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 RJW65256.1 - 3.7 7.4 14.6 5.7 6.8 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ras PF00071.22 RJW65257.1 - 4.5e-60 201.9 0.1 6.1e-60 201.5 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW65257.1 - 4e-33 114.2 0.0 6.1e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW65257.1 - 7.2e-12 45.1 0.0 9.9e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW65257.1 - 8.6e-05 22.6 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RJW65257.1 - 0.0022 17.6 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RJW65257.1 - 0.0035 17.3 0.0 0.26 11.2 0.0 2.5 1 1 2 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 RJW65257.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TetR_C_16 PF17920.1 RJW65257.1 - 0.04 14.2 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_22 PF13401.6 RJW65257.1 - 0.045 14.0 0.0 0.17 12.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 RJW65257.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Tubulin_C PF03953.17 RJW65258.1 - 9.2e-42 142.2 0.2 1.5e-41 141.5 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 RJW65258.1 - 9.6e-34 117.3 0.0 1.9e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 RJW65258.1 - 0.0078 15.9 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Histone PF00125.24 RJW65259.1 - 7.4e-54 181.6 1.5 8.3e-54 181.5 1.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RJW65259.1 - 7.4e-05 22.8 0.2 0.00016 21.8 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 RJW65259.1 - 8.5e-05 23.2 1.6 0.0001 22.9 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 RJW65259.1 - 0.00046 20.5 0.0 0.0007 19.9 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 RJW65259.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Tubulin PF00091.25 RJW65260.1 - 3.6e-71 239.4 0.0 5.7e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW65260.1 - 8.3e-44 148.8 0.1 1.3e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RJW65260.1 - 1.9e-05 24.9 0.0 5.3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RJW65260.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RJW65260.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Abhydrolase_2 PF02230.16 RJW65263.1 - 9e-52 176.0 0.0 1e-51 175.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 RJW65263.1 - 7.4e-06 25.4 0.1 0.061 12.6 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 RJW65263.1 - 4.6e-05 23.2 0.0 5.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 RJW65263.1 - 0.00058 19.5 0.0 0.0007 19.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.22 RJW65263.1 - 0.0038 17.2 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.21 RJW65263.1 - 0.011 15.3 0.8 1.3 8.4 0.2 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 RJW65263.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF2974 PF11187.8 RJW65263.1 - 0.011 15.3 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 RJW65263.1 - 0.043 13.7 0.0 0.068 13.0 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Usp PF00582.26 RJW65265.1 - 3.2e-19 69.8 0.0 7.6e-19 68.6 0.0 1.6 1 1 0 1 1 1 1 Universal stress protein family SET PF00856.28 RJW65266.1 - 1.7e-05 25.3 0.0 4.6e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 SET domain PHD PF00628.29 RJW65266.1 - 0.079 12.9 9.6 0.17 11.8 9.6 1.6 1 0 0 1 1 1 0 PHD-finger PA26 PF04636.13 RJW65267.1 - 2.8e-109 366.0 0.0 3.4e-109 365.7 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Ric8 PF10165.9 RJW65268.1 - 2e-55 188.7 6.6 1.8e-54 185.5 7.2 1.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn Hamartin PF04388.12 RJW65268.1 - 0.051 12.2 0.4 0.071 11.8 0.4 1.1 1 0 0 1 1 1 0 Hamartin protein MFS_1 PF07690.16 RJW65269.1 - 6.6e-16 58.2 21.7 1.1e-15 57.5 19.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC_membrane_3 PF13748.6 RJW65269.1 - 0.016 14.5 0.2 0.075 12.3 0.2 2.2 1 1 1 2 2 2 0 ABC transporter transmembrane region ApoO PF09769.9 RJW65269.1 - 0.92 9.5 3.4 45 4.0 0.3 3.4 3 0 0 3 3 3 0 Apolipoprotein O HMG_box PF00505.19 RJW65270.1 - 1e-21 77.1 6.6 9.2e-18 64.4 1.4 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW65270.1 - 2.2e-16 60.2 6.0 1.7e-12 47.8 1.2 2.2 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 RJW65270.1 - 0.46 10.5 5.1 2.3 8.2 0.6 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Sec3_C PF09763.9 RJW65271.1 - 1.6e-60 205.4 19.6 6.5e-59 200.0 19.6 2.6 1 1 0 1 1 1 1 Exocyst complex component Sec3 NifQ PF04891.12 RJW65271.1 - 0.028 14.8 0.2 0.2 12.0 0.0 2.6 2 1 1 3 3 3 0 NifQ BCIP PF13862.6 RJW65271.1 - 0.11 12.2 1.3 0.28 10.9 1.3 1.7 1 0 0 1 1 1 0 p21-C-terminal region-binding protein CH_2 PF06294.11 RJW65271.1 - 0.18 12.0 1.1 47 4.2 0.0 3.8 3 0 0 3 3 3 0 CH-like domain in sperm protein Casc1_N PF15927.5 RJW65271.1 - 2.2 7.9 6.6 0.69 9.6 1.5 2.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Ribosomal_60s PF00428.19 RJW65274.1 - 2.9e-26 91.9 6.9 4.1e-26 91.4 6.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein GST_N_3 PF13417.6 RJW65275.1 - 2.6e-16 59.8 0.0 6.7e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RJW65275.1 - 1.2e-14 54.3 0.0 3.7e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RJW65275.1 - 5.8e-14 52.2 0.0 3.1e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RJW65275.1 - 4.6e-05 23.5 0.0 8.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RJW65275.1 - 0.00013 21.9 0.0 0.00061 19.8 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RJW65275.1 - 0.00016 21.9 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RJW65275.1 - 0.0059 17.3 0.0 0.22 12.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 RJW65275.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin GST_C_5 PF16865.5 RJW65275.1 - 0.039 14.5 0.0 0.35 11.5 0.0 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 RJW65275.1 - 0.2 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein DUF2048 PF09752.9 RJW65279.1 - 6.4e-105 351.1 0.0 9.8e-105 350.5 0.0 1.2 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 RJW65279.1 - 1.8e-07 32.0 0.0 7.4e-06 26.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 RJW65279.1 - 0.069 12.8 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 RJW65279.1 - 0.11 12.0 0.1 1.2 8.6 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 RJW65279.1 - 0.14 11.8 0.1 9.2 5.8 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold PH_17 PF18012.1 RJW65279.1 - 0.16 11.7 0.2 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 PH domain PyrBI_leader PF08052.11 RJW65281.1 - 0.066 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 PyrBI operon leader peptide 7tm_1 PF00001.21 RJW65283.1 - 5.2e-05 22.7 11.5 7.8e-05 22.1 11.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW65283.1 - 0.0082 15.8 12.8 0.016 14.8 12.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx MBOAT PF03062.19 RJW65284.1 - 2.3e-31 109.4 31.6 2.3e-31 109.4 31.6 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 RJW65284.1 - 0.018 15.3 6.5 0.018 15.3 6.5 2.7 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family DUF3593 PF12159.8 RJW65284.1 - 3.5 7.7 9.4 0.083 12.9 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3593) GAS2 PF02187.17 RJW65285.1 - 1.1e-24 86.3 0.8 2.8e-24 85.0 0.8 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 RJW65285.1 - 2.8e-07 30.7 0.0 0.00021 21.4 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain TIR_2 PF13676.6 RJW65286.1 - 9.5e-07 29.4 0.0 2.8e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 TIR domain RTP1_C1 PF10363.9 RJW65286.1 - 0.019 15.2 0.1 0.041 14.1 0.1 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 RJW65286.1 - 0.062 12.6 0.4 0.11 11.7 0.4 1.4 1 0 0 1 1 1 0 V-ATPase subunit H SAM_1 PF00536.30 RJW65286.1 - 0.071 13.6 0.1 0.47 10.9 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 RJW65286.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 RJW65288.1 - 2e-14 54.2 0.0 4.9e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 TIR domain SAM_1 PF00536.30 RJW65288.1 - 0.00011 22.5 0.5 0.0012 19.3 0.5 2.3 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RJW65288.1 - 0.011 15.9 0.1 0.027 14.6 0.1 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) V-ATPase_H_N PF03224.14 RJW65288.1 - 0.025 13.9 0.3 0.048 12.9 0.3 1.5 1 0 0 1 1 1 0 V-ATPase subunit H SAM_PNT PF02198.16 RJW65288.1 - 0.055 13.4 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Bestrophin PF01062.21 RJW65289.1 - 5.9e-66 222.9 4.9 8.7e-66 222.3 4.9 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel MOLO1 PF17175.4 RJW65290.1 - 7.3e-11 42.2 0.1 1.6e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 RJW65290.1 - 0.18 12.0 0.0 3.1 8.0 0.0 2.1 1 1 0 1 1 1 0 TPM domain Mltc_N PF11873.8 RJW65290.1 - 0.24 11.1 0.0 0.38 10.5 0.0 1.2 1 0 0 1 1 1 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain Ldl_recept_a PF00057.18 RJW65291.1 - 7.9e-07 29.2 9.1 1.5e-06 28.3 9.1 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A LapA_dom PF06305.11 RJW65291.1 - 0.019 14.8 1.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TMEM132D_C PF15706.5 RJW65291.1 - 0.058 13.2 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term THEG4 PF15834.5 RJW65291.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Testis highly expressed protein 4 ANAPC4_WD40 PF12894.7 RJW65293.1 - 2.3e-08 34.2 1.7 0.00018 21.8 0.1 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW65293.1 - 2.8e-08 34.3 23.8 0.00018 22.2 1.2 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat adh_short PF00106.25 RJW65294.1 - 4e-42 143.9 0.0 6.5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW65294.1 - 1.5e-25 90.2 0.0 3.8e-25 88.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW65294.1 - 2.1e-05 24.5 0.2 0.00036 20.5 0.2 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RJW65294.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Med11 PF10280.9 RJW65295.1 - 6.4e-10 39.6 0.1 8e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein Sec34 PF04136.15 RJW65295.1 - 0.014 15.3 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 Sec34-like family SieB PF14163.6 RJW65295.1 - 0.041 13.4 0.1 0.059 12.9 0.1 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B TIG_plexin PF17960.1 RJW65296.1 - 0.024 14.6 0.0 0.093 12.7 0.0 1.9 2 0 0 2 2 2 0 TIG domain APG6_N PF17675.1 RJW65299.1 - 0.033 14.7 10.6 0.06 13.9 10.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Sec34 PF04136.15 RJW65299.1 - 0.2 11.6 7.9 1.7 8.5 1.0 2.3 1 1 1 2 2 2 0 Sec34-like family DUF1664 PF07889.12 RJW65299.1 - 0.33 11.0 7.7 2.5 8.2 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PI3K_P85_iSH2 PF16454.5 RJW65299.1 - 0.35 10.4 9.3 0.56 9.8 9.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cob_adeno_trans PF01923.18 RJW65299.1 - 0.43 10.7 2.0 0.71 10.0 1.1 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Spc7 PF08317.11 RJW65299.1 - 0.47 9.3 11.5 0.26 10.1 9.6 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 RJW65299.1 - 0.69 10.0 10.9 1.5 8.9 10.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 RJW65299.1 - 2.3 8.4 11.7 5 7.3 11.7 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase HMMR_N PF15905.5 RJW65299.1 - 2.3 7.6 13.8 0.34 10.3 10.1 1.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PRKG1_interact PF15898.5 RJW65299.1 - 2.3 9.2 8.8 2.3 9.2 7.2 1.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Seryl_tRNA_N PF02403.22 RJW65299.1 - 3.1 8.1 7.0 6.6 7.0 7.0 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.14 RJW65299.1 - 3.6 7.4 8.9 5.6 6.8 8.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2205 PF10224.9 RJW65299.1 - 6.3 6.9 9.0 4.3 7.4 1.2 3.2 2 1 1 3 3 3 0 Short coiled-coil protein RhoGAP PF00620.27 RJW65300.1 - 1.9e-42 144.7 0.0 7e-42 142.8 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 RJW65300.1 - 6.3e-39 133.3 0.3 1.2e-38 132.4 0.3 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 RJW65300.1 - 2.2e-09 37.2 0.1 6.4e-09 35.7 0.1 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain ADK PF00406.22 RJW65302.1 - 3.5e-20 72.6 0.0 7.1e-11 42.4 0.0 4.8 4 0 0 4 4 4 3 Adenylate kinase FAP206 PF12018.8 RJW65302.1 - 6.5e-12 45.5 4.2 0.00022 20.8 0.0 5.3 4 2 1 5 5 5 3 Domain of unknown function YHS PF04945.13 RJW65302.1 - 1.1e-11 44.6 1.4 0.00022 21.2 0.0 4.6 4 0 0 4 4 4 3 YHS domain AAA_17 PF13207.6 RJW65302.1 - 4e-11 43.5 14.4 0.0011 19.4 0.0 6.5 6 1 1 7 7 5 3 AAA domain AAA PF00004.29 RJW65302.1 - 8.7e-11 42.4 2.5 0.0025 18.2 0.0 4.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RJW65302.1 - 2.3e-09 37.7 1.7 0.00019 21.7 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 RJW65302.1 - 1.3e-08 35.2 0.1 0.16 12.3 0.0 4.0 3 0 0 3 3 3 3 AAA domain AAA_18 PF13238.6 RJW65302.1 - 2e-08 34.8 2.5 0.14 12.7 0.0 4.9 4 1 0 4 4 4 2 AAA domain AAA_33 PF13671.6 RJW65302.1 - 2.1e-07 31.2 0.5 0.22 11.7 0.0 4.2 4 0 0 4 4 4 2 AAA domain SKI PF01202.22 RJW65302.1 - 3.6e-06 27.2 0.1 0.14 12.3 0.0 3.9 3 0 0 3 3 3 2 Shikimate kinase AAA_16 PF13191.6 RJW65302.1 - 2.2e-05 24.9 1.8 2.9 8.3 0.0 4.6 4 0 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.27 RJW65302.1 - 5.9e-05 23.6 0.1 9 6.8 0.0 4.3 4 1 0 4 4 3 0 ABC transporter AAA_24 PF13479.6 RJW65302.1 - 6.5e-05 22.7 0.1 0.14 11.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 RJW65302.1 - 8.7e-05 22.6 0.0 0.2 11.7 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase Hydin_ADK PF17213.3 RJW65302.1 - 0.00014 22.2 0.2 0.023 15.0 0.0 3.1 3 0 0 3 3 2 1 Hydin Adenylate kinase-like domain AAA_5 PF07728.14 RJW65302.1 - 0.00059 19.8 0.3 0.75 9.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 RJW65302.1 - 0.0013 19.1 0.0 3.6 8.0 0.0 3.5 4 0 0 4 4 3 1 RNA helicase Rad17 PF03215.15 RJW65302.1 - 0.006 16.5 0.1 4.3 7.2 0.0 3.6 4 0 0 4 4 4 1 Rad17 P-loop domain Mg_chelatase PF01078.21 RJW65302.1 - 0.0068 15.8 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.23 RJW65302.1 - 0.0097 16.0 1.4 63 3.6 0.0 4.6 4 0 0 4 4 4 0 Dynamin family AAA_14 PF13173.6 RJW65302.1 - 0.021 14.9 0.0 3.5 7.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 RJW65302.1 - 0.034 14.4 0.0 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 RJW65302.1 - 0.037 13.3 0.0 0.99 8.6 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin Cytidylate_kin PF02224.18 RJW65302.1 - 0.055 13.2 0.0 5.1 6.8 0.0 3.3 3 0 0 3 3 3 0 Cytidylate kinase RuvB_N PF05496.12 RJW65302.1 - 0.087 12.6 0.1 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 RJW65302.1 - 0.1 12.1 0.0 14 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 RJW65302.1 - 0.13 12.1 0.0 25 4.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ADK PF00406.22 RJW65305.1 - 1.9e-11 44.3 0.0 2.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RJW65305.1 - 9e-05 22.9 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 RJW65305.1 - 0.0037 17.7 0.0 0.0047 17.4 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RJW65305.1 - 0.0044 17.3 0.0 0.0057 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RJW65305.1 - 0.0094 16.3 0.0 0.018 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 RJW65305.1 - 0.0096 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 RJW65305.1 - 0.013 16.0 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RJW65305.1 - 0.017 15.3 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RJW65305.1 - 0.02 15.2 0.0 0.035 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 RJW65305.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase NACHT PF05729.12 RJW65305.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Telomere_reg-2 PF10193.9 RJW65305.1 - 0.19 12.2 0.1 0.31 11.5 0.1 1.3 1 0 0 1 1 1 0 Telomere length regulation protein MFS_1 PF07690.16 RJW65306.1 - 7.2e-13 48.2 25.7 7.2e-13 48.2 25.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_60s PF00428.19 RJW65307.1 - 2.9e-26 91.9 6.9 4.1e-26 91.4 6.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein MFS_1 PF07690.16 RJW65309.1 - 7.9e-20 71.1 15.0 1.2e-19 70.5 14.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Aa_trans PF01490.18 RJW65310.1 - 1.6e-64 218.2 27.9 2e-64 217.8 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DHO_dh PF01180.21 RJW65311.1 - 2e-32 112.6 0.0 3.4e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 RJW65311.1 - 2.2e-31 108.0 0.2 2.2e-31 108.0 0.2 2.5 2 1 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 RJW65311.1 - 9.6e-23 80.1 13.5 9.6e-23 80.1 13.5 3.7 3 0 0 3 3 3 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 RJW65311.1 - 1.4e-10 40.9 0.0 9.9e-10 38.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RJW65311.1 - 9.1e-07 29.0 0.0 6.4e-06 26.3 0.0 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RJW65311.1 - 3.6e-05 24.2 0.0 0.058 14.0 0.0 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.7 RJW65311.1 - 6.4e-05 22.9 2.6 6.4e-05 22.9 2.6 4.3 4 0 0 4 4 3 1 4Fe-4S binding domain Fer4_7 PF12838.7 RJW65311.1 - 8.1e-05 23.1 10.2 8.1e-05 23.1 10.2 3.9 3 2 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 RJW65311.1 - 0.00014 21.9 10.0 0.00014 21.9 10.0 3.2 3 1 0 3 3 2 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 RJW65311.1 - 0.00031 20.1 0.0 0.045 13.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.7 RJW65311.1 - 0.0035 17.4 3.4 0.0035 17.4 3.4 5.0 5 0 0 5 5 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 RJW65311.1 - 0.005 17.0 13.1 0.005 17.0 13.1 3.4 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4 PF00037.27 RJW65311.1 - 0.0087 15.8 27.8 0.012 15.4 5.9 4.3 4 0 0 4 4 4 2 4Fe-4S binding domain NAD_binding_7 PF13241.6 RJW65311.1 - 0.018 15.5 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.21 RJW65311.1 - 0.052 12.9 0.0 4.1 6.7 0.0 2.4 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.20 RJW65311.1 - 0.099 12.7 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fer4_4 PF12800.7 RJW65311.1 - 2.5 8.8 25.3 0.29 11.8 3.0 4.4 3 0 0 3 3 3 0 4Fe-4S binding domain Methyltransf_10 PF05971.12 RJW65312.1 - 1.2e-70 238.2 0.0 1.7e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 RJW65312.1 - 0.033 13.7 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 RJW65312.1 - 0.038 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 RJW65312.1 - 0.045 13.1 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) EF-hand_7 PF13499.6 RJW65313.1 - 3.1e-12 46.8 0.1 4.8e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW65313.1 - 5.6e-11 41.2 0.6 4.1e-06 26.0 0.4 2.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 RJW65313.1 - 1.5e-10 40.0 0.2 0.00022 20.6 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW65313.1 - 2.3e-10 39.6 0.1 0.0001 21.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RJW65313.1 - 6.6e-05 22.7 1.4 0.15 11.9 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW65313.1 - 0.00087 19.6 0.0 0.001 19.4 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region XPG_I PF00867.18 RJW65314.1 - 4.9e-32 110.2 0.0 9.6e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 RJW65314.1 - 1e-26 93.4 0.0 1.9e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 RJW65314.1 - 8.1e-07 29.6 0.0 3.1e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Fe_dep_repr_C PF02742.15 RJW65314.1 - 0.0053 16.8 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 2 Iron dependent repressor, metal binding and dimerisation domain HHH_5 PF14520.6 RJW65314.1 - 0.0082 16.7 0.4 0.24 12.0 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF3560 PF12083.8 RJW65314.1 - 0.076 13.2 0.1 11 6.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) XPG_I_2 PF12813.7 RJW65314.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 XPG domain containing PLDc_2 PF13091.6 RJW65315.1 - 2.3e-06 27.5 0.0 3.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 RJW65315.1 - 0.0061 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D Active site motif bZIP_1 PF00170.21 RJW65316.1 - 2.7e-11 43.4 12.6 2.7e-11 43.4 12.6 1.8 2 0 0 2 2 2 1 bZIP transcription factor Jun PF03957.13 RJW65316.1 - 1.6e-07 31.5 3.2 3.4e-07 30.4 3.2 1.7 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_Maf PF03131.17 RJW65316.1 - 3.8e-06 27.3 9.4 3.8e-06 27.3 9.4 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 RJW65316.1 - 6.9e-06 26.0 15.8 6.9e-06 26.0 15.8 2.2 3 0 0 3 3 3 1 Basic region leucine zipper Sipho_Gp157 PF05565.11 RJW65316.1 - 0.0013 18.8 0.6 0.0026 17.8 0.6 1.4 1 0 0 1 1 1 1 Siphovirus Gp157 ASD2 PF08687.11 RJW65316.1 - 0.0094 15.5 0.5 0.0094 15.5 0.5 1.8 3 0 0 3 3 3 1 Apx/Shroom domain ASD2 Prominin PF05478.11 RJW65316.1 - 0.06 11.3 0.4 0.17 9.8 0.0 1.8 2 0 0 2 2 2 0 Prominin DUF3301 PF11743.8 RJW65316.1 - 0.09 12.5 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) TSC22 PF01166.18 RJW65316.1 - 0.31 11.4 1.3 2.1 8.7 0.4 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family Spc29 PF17082.5 RJW65316.1 - 1.3 8.8 7.7 1.3 8.8 2.9 2.6 2 1 1 3 3 3 0 Spindle Pole Component 29 TBCC_N PF16752.5 RJW65316.1 - 3.8 8.0 9.3 0.34 11.3 0.2 3.2 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Transformer PF06495.11 RJW65316.1 - 6.7 6.8 12.2 1.8 8.6 5.9 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein 3HCDH_N PF02737.18 RJW65317.1 - 4.2e-55 186.4 0.6 7.6e-55 185.6 0.6 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 RJW65317.1 - 8.4e-36 123.6 0.2 1.5e-35 122.8 0.2 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 RJW65317.1 - 2.3e-28 98.7 0.0 2.7e-22 79.2 0.0 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 RJW65317.1 - 4.8e-22 78.9 0.1 7.9e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase bZIP_1 PF00170.21 RJW65319.1 - 0.17 12.0 0.5 0.28 11.3 0.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor EF-hand_7 PF13499.6 RJW65321.1 - 1.2e-15 57.7 9.9 3e-07 30.8 0.4 6.1 7 1 1 8 8 8 4 EF-hand domain pair EF-hand_11 PF08976.11 RJW65321.1 - 2.7e-07 31.4 3.6 0.3 12.0 0.0 5.8 6 0 0 6 6 6 1 EF-hand domain EF-hand_6 PF13405.6 RJW65321.1 - 4.2e-07 29.4 6.3 2.8 8.1 0.1 7.2 7 0 0 7 7 7 2 EF-hand domain EF-hand_9 PF14658.6 RJW65321.1 - 7.6e-07 29.4 0.1 0.17 12.3 0.0 5.9 7 0 0 7 7 7 1 EF-hand domain EF-hand_1 PF00036.32 RJW65321.1 - 1.3e-06 27.5 0.2 7.9 6.3 0.1 6.6 6 0 0 6 6 6 1 EF hand EF-hand_8 PF13833.6 RJW65321.1 - 3.9e-06 26.6 1.4 1.8 8.5 0.1 5.7 4 2 2 6 6 6 3 EF-hand domain pair EF-hand_12 PF17901.1 RJW65321.1 - 0.17 12.3 0.3 1.7 9.2 0.1 2.7 3 0 0 3 3 3 0 EF-hand fold domain PLDc_2 PF13091.6 RJW65322.1 - 1.3e-16 60.7 0.0 4.8e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RJW65322.1 - 1.3e-07 31.5 0.0 0.023 14.9 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Peptidase_M20 PF01546.28 RJW65323.1 - 3.8e-33 114.9 0.0 4.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RJW65323.1 - 3.3e-07 30.2 0.0 9e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Palm_thioest PF02089.15 RJW65324.1 - 1e-84 284.2 0.0 1.2e-84 284.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 RJW65324.1 - 0.027 14.1 0.1 0.079 12.6 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 RJW65324.1 - 0.051 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal zf-NOSIP PF15906.5 RJW65325.1 - 2.4e-36 123.7 0.6 2.4e-36 123.7 0.6 1.8 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 RJW65325.1 - 3.9e-08 33.0 7.8 9.1e-05 22.0 0.2 2.7 1 1 2 3 3 3 2 Rtf2 RING-finger U-box PF04564.15 RJW65325.1 - 5e-06 26.6 0.0 0.0022 18.2 0.0 2.5 2 0 0 2 2 2 2 U-box domain Phage_Nu1 PF07471.12 RJW65325.1 - 0.14 11.9 1.5 0.24 11.2 1.5 1.3 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Peptidase_S8 PF00082.22 RJW65326.1 - 6.9e-32 110.9 0.0 1.1e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Paramyxo_P PF01806.17 RJW65328.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region zf-C4 PF00105.18 RJW65331.1 - 6.3e-25 87.4 17.5 2e-24 85.8 17.5 1.9 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW65331.1 - 0.00067 19.3 0.2 0.0013 18.4 0.2 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SOCS_box PF07525.16 RJW65333.1 - 2.8e-07 30.8 0.6 6.9e-07 29.5 0.6 1.7 1 0 0 1 1 1 1 SOCS box DnaJ PF00226.31 RJW65335.1 - 0.09 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain Ank_3 PF13606.6 RJW65337.1 - 2.6e-11 42.7 0.3 0.0024 18.2 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat TPR_12 PF13424.6 RJW65337.1 - 3.3e-11 43.3 11.3 0.0054 17.0 0.2 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat Ank_2 PF12796.7 RJW65337.1 - 6e-11 42.8 0.0 4.5e-08 33.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW65337.1 - 1.1e-06 29.1 0.1 0.0006 20.3 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW65337.1 - 3.9e-06 27.0 0.3 0.00025 21.3 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) TPR_7 PF13176.6 RJW65337.1 - 0.00013 21.8 3.0 17 5.7 0.0 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 RJW65337.1 - 0.00016 21.6 3.9 4.7 7.7 0.1 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat Ank PF00023.30 RJW65337.1 - 0.00067 20.0 0.8 0.09 13.3 0.0 3.6 4 0 0 4 4 3 1 Ankyrin repeat TPR_2 PF07719.17 RJW65337.1 - 0.00099 19.0 9.5 0.95 9.7 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RJW65337.1 - 0.001 18.8 4.3 4.6 7.2 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW65337.1 - 0.0011 18.4 3.9 0.54 9.6 0.0 3.2 3 0 0 3 3 3 2 MalT-like TPR region Par3_HAL_N_term PF12053.8 RJW65337.1 - 0.023 14.9 0.0 0.071 13.3 0.0 1.9 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins TPR_19 PF14559.6 RJW65337.1 - 0.17 12.4 1.4 2.1 8.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.6 RJW65337.1 - 0.83 9.9 2.5 3.9 7.8 0.2 2.9 3 0 0 3 3 2 0 Leucine Rich repeat HPPK PF01288.20 RJW65339.1 - 0.094 13.2 1.2 0.36 11.3 0.0 2.5 2 1 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) TSC22 PF01166.18 RJW65339.1 - 0.22 11.9 4.4 7.9 6.9 0.4 3.0 2 0 0 2 2 2 0 TSC-22/dip/bun family APG6_N PF17675.1 RJW65339.1 - 2.1 8.8 18.8 2.5 8.6 10.2 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region SOGA PF11365.8 RJW65339.1 - 4.7 8.4 17.2 0.66 11.1 0.9 4.1 4 1 0 4 4 4 0 Protein SOGA BBP1_C PF15272.6 RJW65339.1 - 8.2 6.2 9.8 1.8 8.3 1.3 2.9 2 1 1 3 3 3 0 Spindle pole body component BBP1, C-terminal TetR_C_17 PF17922.1 RJW65341.1 - 0.024 14.7 0.1 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1664 PF07889.12 RJW65341.1 - 3.6 7.6 6.6 1.8 8.6 3.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RVT_1 PF00078.27 RJW65342.1 - 4.7e-13 49.2 0.0 6.6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyl_transf_3 PF01757.22 RJW65343.1 - 0.0019 17.4 12.1 0.0019 17.4 12.1 3.0 1 1 1 2 2 2 2 Acyltransferase family DnaJ_C PF01556.18 RJW65345.1 - 5.3e-27 94.7 0.0 7.4e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RJW65345.1 - 5.2e-26 90.6 6.2 8.7e-26 89.8 6.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RJW65345.1 - 7.4e-11 42.3 13.5 1.3e-10 41.5 13.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 RJW65345.1 - 0.011 15.7 16.4 0.21 11.6 1.8 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TF_Zn_Ribbon PF08271.12 RJW65345.1 - 0.58 9.7 8.7 0.052 13.1 3.5 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding GATA PF00320.27 RJW65345.1 - 0.84 9.3 4.5 1.9 8.2 4.5 1.6 1 0 0 1 1 1 0 GATA zinc finger HypA PF01155.19 RJW65345.1 - 0.99 9.4 7.4 0.46 10.5 0.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 RJW65345.1 - 1.2 8.7 3.6 5.2 6.7 0.0 2.3 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 Sec5 PF15469.6 RJW65347.1 - 1.3e-40 139.3 0.0 2.2e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 TIG PF01833.24 RJW65347.1 - 1.5e-08 34.6 1.0 3.6e-08 33.4 1.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain Sterol-sensing PF12349.8 RJW65348.1 - 1.3e-19 70.5 5.6 2e-10 40.7 0.4 2.7 1 1 1 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 RJW65348.1 - 9.3e-15 53.8 0.1 2.2e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Patched family AdoHcyase PF05221.17 RJW65349.1 - 1.3e-113 379.1 0.0 6.3e-62 209.4 0.1 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 RJW65349.1 - 3.4e-73 245.0 5.1 5e-73 244.5 5.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 RJW65349.1 - 1.3e-09 37.6 0.1 2.5e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 RJW65349.1 - 1.6e-05 24.6 0.0 3.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 RJW65349.1 - 0.00015 22.1 0.6 0.00058 20.3 0.5 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 RJW65349.1 - 0.00016 21.7 0.1 0.00042 20.4 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 RJW65349.1 - 0.0031 17.8 0.4 0.014 15.6 0.4 2.1 1 1 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.19 RJW65349.1 - 0.0042 16.4 3.3 0.017 14.5 3.4 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.21 RJW65349.1 - 0.0073 15.6 1.2 0.015 14.6 1.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UPF0180 PF03698.13 RJW65349.1 - 0.0088 16.2 0.7 2.5 8.3 0.8 2.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0180) AIP3 PF03915.13 RJW65350.1 - 0.36 9.9 8.1 0.14 11.2 4.1 2.1 1 1 1 2 2 2 0 Actin interacting protein 3 Reprolysin_2 PF13574.6 RJW65351.1 - 3.3e-29 102.2 0.2 6.3e-29 101.3 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RJW65351.1 - 8e-22 78.4 0.0 8e-22 78.4 0.0 2.0 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RJW65351.1 - 1.7e-14 54.4 0.4 3.2e-14 53.5 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 RJW65351.1 - 2.1e-12 47.6 26.6 2.1e-12 47.6 26.6 3.1 3 0 0 3 3 3 1 Disintegrin Reprolysin_4 PF13583.6 RJW65351.1 - 1e-10 41.6 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 RJW65351.1 - 0.003 17.5 0.0 0.0069 16.3 0.0 1.6 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pkinase PF00069.25 RJW65352.1 - 2.7e-54 184.3 0.0 7.6e-35 120.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW65352.1 - 2.6e-23 82.6 0.1 3.5e-19 69.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RJW65352.1 - 0.00039 19.8 0.1 0.018 14.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RJW65352.1 - 0.0022 18.0 0.0 0.0056 16.6 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RJW65352.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RJW65352.1 - 0.065 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 RJW65352.1 - 0.079 11.9 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L2_C PF03947.18 RJW65353.1 - 5.1e-16 59.0 0.0 1.3e-15 57.8 0.0 1.7 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RJW65353.1 - 1.4e-07 31.4 0.0 3.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TSP_1 PF00090.19 RJW65354.1 - 3.1e-17 62.5 49.7 9e-06 25.8 3.8 7.2 6 1 0 6 6 6 5 Thrombospondin type 1 domain Ig_3 PF13927.6 RJW65354.1 - 0.0005 20.6 0.0 0.0018 18.8 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RJW65354.1 - 0.0078 16.3 0.0 0.022 14.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain PLAC PF08686.11 RJW65354.1 - 0.85 10.4 11.2 4.7 8.1 11.2 2.5 1 0 0 1 1 1 0 PLAC (protease and lacunin) domain DUF1936 PF09151.10 RJW65355.1 - 0.017 15.1 0.5 8.1 6.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Homeodomain PF00046.29 RJW65357.1 - 3.6e-20 71.5 7.5 1.5e-19 69.6 7.5 2.2 1 0 0 1 1 1 1 Homeodomain RVT_1 PF00078.27 RJW65363.1 - 3e-35 121.8 0.0 4.6e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PKD_channel PF08016.12 RJW65364.1 - 0.065 11.9 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Polycystin cation channel ThiF PF00899.21 RJW65365.1 - 1.6e-63 214.3 0.0 2.8e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 RJW65365.1 - 8.7e-10 39.1 0.1 4.1e-08 33.7 0.1 2.5 1 1 0 1 1 1 1 Rhodanese-like domain AAA_22 PF13401.6 RJW65365.1 - 0.015 15.6 0.0 0.15 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 RJW65365.1 - 0.017 15.6 0.5 0.41 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ribosomal_L19e PF01280.20 RJW65365.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L19e MTS PF05175.14 RJW65366.1 - 4.6e-11 42.6 0.1 8.1e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 RJW65366.1 - 1.3e-10 41.1 0.3 2.1e-10 40.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 RJW65366.1 - 1.4e-08 34.6 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 RJW65366.1 - 1.9e-06 28.5 0.1 5.6e-06 27.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 RJW65366.1 - 1.6e-05 24.7 0.4 9.7e-05 22.1 0.4 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 RJW65366.1 - 3.8e-05 23.5 0.0 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 RJW65366.1 - 0.0025 17.6 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 RJW65366.1 - 0.0033 17.4 0.2 0.0063 16.5 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 RJW65366.1 - 0.0037 16.9 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 RJW65366.1 - 0.0068 17.0 0.1 0.029 15.0 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain FtsJ PF01728.19 RJW65366.1 - 0.0089 16.1 0.1 0.017 15.2 0.1 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 RJW65366.1 - 0.009 16.7 0.0 0.022 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 RJW65366.1 - 0.01 15.5 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DNA_methylase PF00145.17 RJW65366.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase N6_Mtase PF02384.16 RJW65366.1 - 0.063 12.5 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 N-6 DNA Methylase PolyA_pol PF01743.20 RJW65367.1 - 5.4e-28 98.0 0.6 2.2e-25 89.5 0.3 2.3 1 1 1 2 2 2 2 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 RJW65367.1 - 1.9e-10 40.3 0.3 6.4e-10 38.7 0.0 2.0 3 0 0 3 3 3 1 Probable RNA and SrmB- binding site of polymerase A DUF2151 PF10221.9 RJW65368.1 - 0.094 11.3 13.0 0.11 11.0 13.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator GAGA_bind PF06217.12 RJW65368.1 - 0.68 10.2 9.5 0.74 10.1 9.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family eIF-3_zeta PF05091.12 RJW65368.1 - 0.68 8.8 15.4 0.83 8.6 15.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 RJW65368.1 - 0.71 8.2 1.9 0.97 7.8 1.9 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 RJW65368.1 - 0.83 9.4 19.7 1.2 8.9 19.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 RJW65368.1 - 0.89 8.9 18.4 1.1 8.6 18.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAA_11 PF13086.6 RJW65368.1 - 2.1 8.1 17.8 2.6 7.7 17.8 1.2 1 0 0 1 1 1 0 AAA domain ALMT PF11744.8 RJW65368.1 - 3 6.6 9.4 3.3 6.4 9.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 RJW65368.1 - 3.6 6.2 22.1 4.2 6.0 22.1 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 RJW65368.1 - 3.6 6.5 5.5 4.6 6.1 5.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BORG_CEP PF14957.6 RJW65368.1 - 8.8 7.5 6.8 14 6.9 6.8 1.4 1 0 0 1 1 1 0 Cdc42 effector CDC45 PF02724.14 RJW65368.1 - 9.1 4.4 36.2 11 4.2 36.2 1.0 1 0 0 1 1 1 0 CDC45-like protein PRP38_assoc PF12871.7 RJW65368.1 - 9.2 6.9 89.7 1.8e+04 -4.0 89.7 2.7 1 1 0 1 1 0 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RVT_1 PF00078.27 RJW65369.1 - 6.3e-15 55.3 0.0 3.8e-14 52.7 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Stk19 PF10494.9 RJW65370.1 - 1.9e-24 86.7 0.5 5.6e-24 85.2 0.5 1.7 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 TRAPPC-Trs85 PF12739.7 RJW65370.1 - 0.13 11.2 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit OSTMP1 PF09777.9 RJW65371.1 - 3.1e-23 82.4 4.0 2.1e-21 76.4 4.0 2.3 1 1 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor Glyco_hydro_3_C PF01915.22 RJW65373.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.7 1 1 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Dor1 PF04124.12 RJW65374.1 - 7.3e-20 70.9 0.7 8.2e-07 28.0 0.0 3.4 4 0 0 4 4 4 3 Dor1-like family Exo_endo_phos PF03372.23 RJW65375.1 - 3.4e-09 36.6 0.0 1.6e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF389 PF04087.14 RJW65377.1 - 4.8e-36 123.9 3.2 4.8e-36 123.9 3.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF389) DUF294_C PF10335.9 RJW65377.1 - 0.07 12.9 1.2 1.3 8.8 0.2 2.5 2 1 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain BACK PF07707.15 RJW65378.1 - 0.00047 20.2 0.1 0.002 18.2 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 RJW65378.1 - 0.00065 19.9 0.0 0.0059 16.8 0.0 2.5 2 1 1 3 3 3 1 BTB/POZ domain Lenti_VIF_2 PF07401.12 RJW65378.1 - 0.022 14.1 0.1 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein WD40 PF00400.32 RJW65379.1 - 7.6e-08 32.9 7.8 0.27 12.2 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 RJW65379.1 - 0.02 13.6 0.1 0.029 13.0 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF3522 PF12036.8 RJW65380.1 - 3.9e-30 105.5 9.5 3.4e-18 66.6 4.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3522) HLH PF00010.26 RJW65380.1 - 2.5e-12 46.6 1.2 4.8e-12 45.7 1.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2205 PF10224.9 RJW65380.1 - 0.089 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Short coiled-coil protein BNIP2 PF12496.8 RJW65380.1 - 0.78 10.2 4.9 1 9.8 3.7 1.8 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF2628 PF10947.8 RJW65380.1 - 7 7.1 8.0 0.47 10.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) DUF702 PF05142.12 RJW65382.1 - 0.043 14.3 0.1 0.095 13.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF702) PTB PF08416.13 RJW65383.1 - 5.9e-07 29.7 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 RJW65383.1 - 0.00011 22.3 0.0 0.00026 21.0 0.0 1.8 1 0 0 1 1 1 1 SH2 domain VHS PF00790.19 RJW65385.1 - 1.1e-23 83.6 0.2 1.7e-23 83.0 0.2 1.3 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 RJW65385.1 - 1.4e-16 59.8 0.1 2.4e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RJW65385.1 - 1.8e-12 46.9 0.1 3.7e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RJW65385.1 - 3.3e-12 45.9 0.0 5.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 RJW65385.1 - 0.0011 18.8 1.2 0.0011 18.8 1.2 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif SH3_10 PF17902.1 RJW65385.1 - 0.02 15.0 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 SH3 domain Integrase_H2C2 PF17921.1 RJW65387.1 - 2.2e-16 59.7 0.2 4.1e-16 58.8 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RJW65387.1 - 1e-07 32.0 0.0 2.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Methyltr_RsmB-F PF01189.17 RJW65389.1 - 5.8e-22 78.3 4.1 5e-12 45.9 0.0 4.1 5 0 0 5 5 5 3 16S rRNA methyltransferase RsmB/F DUF241 PF03087.14 RJW65389.1 - 0.012 15.5 1.5 0.032 14.0 1.5 1.7 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Methyltransf_25 PF13649.6 RJW65389.1 - 0.026 15.2 0.0 0.48 11.2 0.0 2.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 RJW65389.1 - 0.027 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 RJW65389.1 - 0.03 14.4 0.0 0.064 13.4 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase tRNA_m1G_MT PF01746.21 RJW65389.1 - 0.062 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase Trypsin PF00089.26 RJW65392.1 - 2.8e-10 40.4 0.0 4.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin Serpin PF00079.20 RJW65393.1 - 3.1e-88 296.6 0.0 3.5e-88 296.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1441 PF07278.11 RJW65393.1 - 0.054 13.4 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1441) Asp PF00026.23 RJW65398.1 - 8.3e-43 147.0 0.0 9.6e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW65398.1 - 1.2e-07 31.7 0.1 1e-05 25.4 0.0 2.2 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RJW65398.1 - 3.3e-05 24.4 0.1 0.17 12.6 0.0 3.5 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 RJW65398.1 - 0.00066 20.2 0.1 5.3 7.7 0.0 3.6 2 2 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 RJW65398.1 - 0.023 14.9 0.0 0.73 10.0 0.0 2.4 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal FAM86 PF14904.6 RJW65399.1 - 0.019 15.0 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function PH PF00169.29 RJW65400.1 - 0.006 17.1 0.1 0.016 15.7 0.0 1.8 1 1 0 1 1 1 1 PH domain ELO PF01151.18 RJW65401.1 - 1.8e-56 191.5 18.0 2.1e-56 191.2 18.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PRIMA1 PF16101.5 RJW65402.1 - 0.045 13.8 2.2 0.27 11.3 0.9 2.3 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 Serglycin PF04360.12 RJW65403.1 - 0.016 15.2 0.9 0.034 14.1 0.9 1.5 1 0 0 1 1 1 0 Serglycin Comm PF15957.5 RJW65403.1 - 0.86 10.0 3.1 1.7 9.0 2.3 2.1 2 1 0 2 2 2 0 Commissureless Inj_translocase PF16928.5 RJW65403.1 - 2.4 7.6 8.1 0.044 13.2 1.2 1.6 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome Peptidase_C48 PF02902.19 RJW65405.1 - 1.9e-37 129.2 0.0 1.9e-37 129.2 0.0 1.9 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 RJW65405.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus endoprotease Ank_5 PF13857.6 RJW65406.1 - 4.4e-07 30.0 0.0 6.5e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW65406.1 - 4.5e-06 27.1 0.0 6.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW65406.1 - 1.3e-05 25.7 0.0 1.8e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RJW65406.1 - 0.00073 19.9 0.0 0.0021 18.4 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 RJW65406.1 - 0.0052 17.2 0.0 0.024 15.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat ASH PF15780.5 RJW65407.1 - 1.6e-08 34.7 0.4 1.6e-05 25.1 0.1 2.5 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SAP PF02037.27 RJW65408.1 - 4.6e-08 32.6 4.6 1e-07 31.5 3.7 2.0 2 0 0 2 2 2 1 SAP domain Rho_N PF07498.12 RJW65408.1 - 0.12 12.3 0.6 0.24 11.3 0.6 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Dynamitin PF04912.14 RJW65409.1 - 0.033 13.5 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 Dynamitin DUF4835 PF16119.5 RJW65409.1 - 0.089 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) APC1_C PF18122.1 RJW65410.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain RVT_1 PF00078.27 RJW65413.1 - 0.12 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DnaJ PF00226.31 RJW65414.1 - 4.7e-09 36.3 0.1 1.1e-08 35.1 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 RJW65414.1 - 1.9e-05 24.3 0.0 7.3e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 GYF domain 2 Trypsin PF00089.26 RJW65416.1 - 7.8e-21 74.9 0.8 6.2e-20 72.0 0.8 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RJW65416.1 - 0.0044 17.9 0.0 0.0067 17.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S9 PF00326.21 RJW65417.1 - 1.3e-08 34.6 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 RJW65417.1 - 1.5e-07 30.5 0.0 4.4e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_2 PF02230.16 RJW65417.1 - 0.05 13.4 0.0 0.35 10.6 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Cu_bind_like PF02298.17 RJW65417.1 - 0.069 13.2 0.1 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Plastocyanin-like domain Granulin PF00396.18 RJW65418.1 - 3.4e-11 43.3 30.8 7.5e-11 42.2 25.1 2.1 1 1 1 2 2 2 2 Granulin ArgoL1 PF08699.10 RJW65419.1 - 0.098 12.3 0.1 0.27 10.9 0.1 1.7 2 0 0 2 2 2 0 Argonaute linker 1 domain Complex1_51K PF01512.17 RJW65420.1 - 3.3e-50 169.9 0.0 5.3e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 RJW65420.1 - 1.5e-29 101.9 1.8 2.8e-29 101.0 0.6 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 RJW65420.1 - 3.8e-07 29.9 0.0 7.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF780 PF05611.11 RJW65420.1 - 0.081 13.7 0.7 0.18 12.6 0.7 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) Pkinase_Tyr PF07714.17 RJW65421.1 - 1.4e-82 276.8 0.0 2.5e-82 276.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW65421.1 - 8e-40 136.9 0.0 1.4e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RJW65421.1 - 3e-06 27.2 0.0 7.4e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 SH2 domain Jnk-SapK_ap_N PF09744.9 RJW65421.1 - 0.008 16.4 2.1 0.018 15.3 2.1 1.6 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Kinase-like PF14531.6 RJW65421.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Prefoldin_2 PF01920.20 RJW65421.1 - 0.14 12.1 0.2 0.37 10.8 0.2 1.7 1 0 0 1 1 1 0 Prefoldin subunit QVR PF17064.5 RJW65421.1 - 0.76 10.1 4.2 2 8.7 4.2 1.7 1 0 0 1 1 1 0 Sleepless protein ArfGap PF01412.18 RJW65423.1 - 1.1e-30 106.0 0.0 3.9e-30 104.3 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 RJW65423.1 - 3.6e-16 59.6 5.7 3.6e-16 59.6 5.7 1.5 2 0 0 2 2 2 1 BAR domain of APPL family SH3_1 PF00018.28 RJW65423.1 - 6.1e-12 44.9 0.1 6.1e-12 44.9 0.1 1.9 2 0 0 2 2 1 1 SH3 domain PH PF00169.29 RJW65423.1 - 4.9e-11 43.1 0.1 1.7e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.6 RJW65423.1 - 1.4e-10 40.9 0.1 3.4e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RJW65423.1 - 1.7e-08 34.0 0.0 3.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 RJW65423.1 - 5.2e-08 33.4 0.0 2.5e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW65423.1 - 7.5e-08 32.8 0.1 3.2e-07 30.8 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW65423.1 - 1.7e-07 31.3 0.0 1.1e-05 25.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW65423.1 - 2.4e-05 24.3 0.1 0.0042 17.5 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RJW65423.1 - 3.5e-05 24.0 0.4 0.0059 17.0 0.2 2.9 2 0 0 2 2 2 1 Ankyrin repeat IMD PF08397.11 RJW65423.1 - 0.0001 21.8 1.0 0.0001 21.8 1.0 1.9 2 0 0 2 2 2 1 IRSp53/MIM homology domain BAR PF03114.18 RJW65423.1 - 0.00086 19.0 3.5 0.0014 18.3 3.5 1.3 1 0 0 1 1 1 1 BAR domain PH_9 PF15410.6 RJW65423.1 - 0.0022 18.4 0.0 0.0067 16.8 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain REC1 PF18501.1 RJW65423.1 - 0.021 14.7 1.7 0.039 13.8 1.7 1.5 1 0 0 1 1 1 0 Alpha helical recognition lobe domain PH_11 PF15413.6 RJW65423.1 - 0.033 14.6 0.0 0.08 13.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Serpin PF00079.20 RJW65424.1 - 2.6e-86 290.3 0.0 2.9e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1441 PF07278.11 RJW65424.1 - 0.056 13.4 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1441) G-alpha PF00503.20 RJW65425.1 - 1.4e-116 389.6 1.5 1.7e-116 389.2 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RJW65425.1 - 2.8e-13 49.7 0.8 2.7e-09 36.7 0.1 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW65425.1 - 0.0041 16.5 0.2 0.65 9.3 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 RJW65425.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 RJW65425.1 - 0.09 13.0 0.1 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rota_NSP4 PF01452.16 RJW65425.1 - 0.16 11.6 1.0 0.28 10.8 0.4 1.7 2 0 0 2 2 2 0 Rotavirus non structural protein Trypsin PF00089.26 RJW65426.1 - 1e-07 32.0 0.0 1.1e-07 31.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin CMD PF02627.20 RJW65426.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family YecM PF06185.12 RJW65426.1 - 0.13 11.9 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 YecM protein DUF4131 PF13567.6 RJW65427.1 - 0.1 12.3 0.2 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Trypsin PF00089.26 RJW65428.1 - 1.2e-07 31.8 0.3 1.5e-07 31.5 0.3 1.2 1 0 0 1 1 1 1 Trypsin Asp PF00026.23 RJW65429.1 - 6.6e-35 121.0 0.0 3.4e-29 102.3 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW65429.1 - 7.4e-08 32.3 0.1 7.8e-06 25.8 0.0 2.2 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RJW65429.1 - 0.00021 21.9 0.3 1.7 9.4 0.1 3.7 2 2 1 3 3 3 2 Aspartyl protease TAXi_N PF14543.6 RJW65429.1 - 0.0023 18.2 0.5 1.4 9.1 0.0 2.7 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 RJW65429.1 - 0.0024 18.4 0.2 5 7.7 0.2 3.3 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Granulin PF00396.18 RJW65431.1 - 4e-12 46.3 20.7 4e-12 46.3 20.7 2.1 2 0 0 2 2 2 1 Granulin FXa_inhibition PF14670.6 RJW65433.1 - 5.6 7.3 24.8 0.8 10.0 1.8 3.6 1 1 2 3 3 3 0 Coagulation Factor Xa inhibitory site DUF98 PF01947.16 RJW65434.1 - 0.019 14.9 0.2 0.032 14.2 0.2 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase DUF3391 PF11871.8 RJW65434.1 - 0.1 13.1 1.7 15 6.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Lsr2 PF11774.8 RJW65435.1 - 0.23 11.6 0.6 0.43 10.7 0.6 1.4 1 0 0 1 1 1 0 Lsr2 Ank_2 PF12796.7 RJW65436.1 - 1.3e-34 118.6 3.1 3.8e-13 49.8 0.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW65436.1 - 1.9e-31 108.1 5.8 1e-09 38.7 0.0 4.8 2 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW65436.1 - 2.4e-26 88.9 8.3 4.3e-05 23.6 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 RJW65436.1 - 2.7e-21 75.3 8.0 3.4e-07 30.4 0.1 5.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 RJW65436.1 - 6.2e-21 73.9 9.7 4.3e-06 26.9 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ion_trans PF00520.31 RJW65436.1 - 7.7e-12 45.0 32.8 2.2e-11 43.5 32.6 1.8 1 1 1 2 2 2 1 Ion transport protein Serpin PF00079.20 RJW65438.1 - 3.4e-29 102.3 0.0 4.1e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) CS PF04969.16 RJW65439.1 - 5.7e-11 43.3 0.2 8.8e-11 42.7 0.2 1.3 1 0 0 1 1 1 1 CS domain WD40 PF00400.32 RJW65441.1 - 2.5e-39 132.5 28.6 2.3e-07 31.4 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW65441.1 - 4.9e-11 42.8 0.4 0.0006 20.1 0.1 4.6 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RJW65441.1 - 0.00052 19.4 0.0 0.03 13.7 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 RJW65441.1 - 0.00086 18.1 1.3 0.45 9.1 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 RJW65441.1 - 0.041 12.4 0.2 2.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Tex_N PF09371.10 RJW65442.1 - 0.19 11.4 2.5 0.22 11.2 0.2 2.2 3 0 0 3 3 3 0 Tex-like protein N-terminal domain EF-hand_4 PF12763.7 RJW65443.1 - 7.7e-29 99.7 0.0 2.5e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 RJW65443.1 - 9.7e-12 43.6 0.2 0.00068 19.0 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RJW65443.1 - 5.2e-06 26.0 0.1 0.28 11.2 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RJW65443.1 - 1.3e-05 25.5 0.0 0.21 12.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW65443.1 - 0.00022 20.6 0.6 0.85 9.2 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW65443.1 - 0.0068 16.2 0.2 3.7 7.5 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair ATG16 PF08614.11 RJW65443.1 - 0.013 15.8 18.6 0.013 15.8 18.6 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Involucrin_N PF10583.9 RJW65443.1 - 0.028 15.0 2.0 0.13 12.8 2.0 2.2 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus AAA_13 PF13166.6 RJW65443.1 - 5.3 5.6 18.4 7.5 5.1 18.4 1.1 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 RJW65443.1 - 8.4 6.4 27.6 1 9.4 8.0 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MFS_1 PF07690.16 RJW65444.1 - 3.7e-45 154.4 21.7 3.7e-45 154.4 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RJW65444.1 - 0.17 11.1 13.3 0.18 11.0 0.8 2.2 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB VPDSG-CTERM PF18205.1 RJW65444.1 - 9.9 6.1 9.2 27 4.7 0.2 3.4 2 0 0 2 2 2 0 VPDSG-CTERM motif G-patch PF01585.23 RJW65445.1 - 1.9e-09 37.3 3.5 0.00018 21.3 0.5 2.7 3 1 0 3 3 3 2 G-patch domain G-patch_2 PF12656.7 RJW65445.1 - 0.092 12.8 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 G-patch domain EF-hand_2 PF09068.11 RJW65446.1 - 1.8e-22 79.8 0.1 3.3e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 RJW65446.1 - 1.1e-16 61.0 0.0 2.5e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand ZZ PF00569.17 RJW65446.1 - 6.4e-12 45.1 6.2 1.3e-11 44.1 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 RJW65446.1 - 0.0011 19.2 6.2 0.0022 18.3 6.2 1.5 1 0 0 1 1 1 1 C1 domain DivIC PF04977.15 RJW65446.1 - 0.35 10.7 7.0 3.7 7.4 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator PAN_1 PF00024.26 RJW65447.1 - 0.019 15.0 1.1 0.03 14.3 0.1 1.8 2 0 0 2 2 2 0 PAN domain PQQ PF01011.21 RJW65448.1 - 0.0067 16.3 0.0 7.8 6.6 0.0 3.3 2 0 0 2 2 2 2 PQQ enzyme repeat CYTL1 PF15153.6 RJW65449.1 - 0.0088 16.0 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Cytokine-like protein 1 ORC5_C PF14630.6 RJW65451.1 - 7.8e-18 65.0 0.0 9.3e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus RVT_1 PF00078.27 RJW65452.1 - 4.8e-19 68.8 0.0 7.1e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arm PF00514.23 RJW65453.1 - 1.7e-25 88.2 16.7 1.3e-07 31.4 0.2 8.9 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 RJW65453.1 - 0.00051 18.7 5.5 0.00091 17.9 1.4 2.6 3 0 0 3 3 3 1 Adaptin N terminal region HEAT_EZ PF13513.6 RJW65453.1 - 0.0029 18.1 5.2 22 5.7 0.0 5.1 4 1 1 5 5 5 0 HEAT-like repeat KAP PF05804.12 RJW65453.1 - 0.0037 15.5 2.0 0.032 12.4 1.9 2.5 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 RJW65453.1 - 0.013 15.0 1.9 0.7 9.3 0.0 2.9 2 1 0 2 2 2 0 Armadillo-like RasGEF_N_2 PF14663.6 RJW65453.1 - 0.049 14.0 0.9 18 5.8 0.2 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.22 RJW65453.1 - 0.11 12.8 4.0 5.9 7.4 0.1 4.1 4 0 0 4 4 4 0 HEAT repeat Mus7 PF09462.10 RJW65453.1 - 0.15 10.9 0.3 0.22 10.3 0.3 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family Drf_GBD PF06371.13 RJW65453.1 - 4.1 6.9 5.6 2.4 7.7 0.2 2.8 2 1 0 2 2 2 0 Diaphanous GTPase-binding Domain Cellulase PF00150.18 RJW65454.1 - 9.4e-36 123.7 0.1 1.4e-35 123.1 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 RJW65454.1 - 7.8e-08 32.8 0.0 1.7e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 RJW65454.1 - 0.018 14.7 0.1 0.03 13.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DUF3659 PF12396.8 RJW65454.1 - 0.3 11.1 0.6 9.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) PI-PLC-X PF00388.19 RJW65455.1 - 3e-32 111.2 0.0 1.4e-30 105.8 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 RJW65455.1 - 7.8e-25 87.5 0.0 2.4e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 RJW65455.1 - 1.8e-09 37.8 0.0 5.7e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 C2 domain DUF1731 PF08338.11 RJW65459.1 - 3.7e-21 74.7 0.1 1.1e-20 73.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 RJW65459.1 - 8.5e-09 35.2 0.1 5.9e-08 32.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 RJW65459.1 - 0.00019 21.1 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RJW65459.1 - 0.00019 21.3 0.2 0.0013 18.6 0.2 2.0 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 RJW65459.1 - 0.0035 16.8 0.1 0.0066 15.9 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 RJW65459.1 - 0.0065 16.4 0.1 1.1 9.2 0.0 2.2 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 RJW65459.1 - 0.032 13.9 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 RJW65459.1 - 0.038 14.6 0.0 0.08 13.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 RJW65459.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 RJW65459.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SNF2_N PF00176.23 RJW65460.1 - 2.1e-64 217.5 0.0 4.5e-64 216.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW65460.1 - 1.4e-17 64.0 0.0 4.1e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_14 PF13173.6 RJW65460.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PH_12 PF16457.5 RJW65462.1 - 2.2e-09 38.0 1.3 8e-07 29.7 1.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 RJW65462.1 - 0.051 14.1 0.0 2.3 8.8 0.0 2.3 2 0 0 2 2 2 0 PH domain PH_14 PF17787.1 RJW65462.1 - 0.11 12.4 0.0 7.9 6.3 0.0 2.2 2 0 0 2 2 2 0 PH domain HlyIII PF03006.20 RJW65463.1 - 1.8e-56 191.4 21.7 2.8e-56 190.7 21.7 1.3 1 0 0 1 1 1 1 Haemolysin-III related YrhK PF14145.6 RJW65463.1 - 0.021 14.7 4.3 0.53 10.2 0.0 3.5 3 0 0 3 3 3 0 YrhK-like protein DUF4405 PF14358.6 RJW65463.1 - 0.041 14.4 2.8 0.041 14.4 2.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) DUF2561 PF10812.8 RJW65463.1 - 8.8 6.3 8.3 3 7.8 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) DUF1744 PF08490.12 RJW65464.1 - 9.4e-97 324.1 0.0 2.4e-96 322.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 RJW65464.1 - 1.4e-60 205.3 0.0 2.2e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 RJW65464.1 - 8.3e-12 44.5 0.0 5.1e-11 42.0 0.0 2.3 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 RJW65464.1 - 1.7e-08 34.4 0.0 4.3e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 RJW65464.1 - 0.0004 20.4 0.0 0.0021 18.1 0.0 2.3 1 1 0 1 1 1 1 RNase_H superfamily zinc_ribbon_4 PF13717.6 RJW65464.1 - 4 7.4 14.7 4.9 7.2 0.2 4.6 4 0 0 4 4 4 0 zinc-ribbon domain CLP1_P PF16575.5 RJW65466.1 - 6.3e-29 101.1 0.0 1.1e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 RJW65466.1 - 0.0039 17.6 0.0 0.0092 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 RJW65466.1 - 0.01 15.1 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 RJW65466.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 RJW65466.1 - 0.23 11.5 0.0 1.8 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Myosin_head PF00063.21 RJW65466.1 - 0.29 9.3 0.0 0.42 8.8 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) WW PF00397.26 RJW65467.1 - 4e-07 30.0 0.1 1.1e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 WW domain WD40 PF00400.32 RJW65468.1 - 8.9e-05 23.2 9.3 0.16 12.9 0.0 5.4 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW65468.1 - 0.0006 20.1 0.2 0.05 13.9 0.0 3.1 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain C2 PF00168.30 RJW65469.1 - 8.7e-18 64.5 0.0 1.9e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain DUF2362 PF10154.9 RJW65470.1 - 1.6e-101 340.8 0.0 2e-101 340.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) TAXi_C PF14541.6 RJW65471.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Fn_bind PF02986.14 RJW65472.1 - 0.034 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Fibronectin binding repeat Pkinase_Tyr PF07714.17 RJW65473.1 - 3.9e-54 183.6 0.0 5.6e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW65473.1 - 3.6e-53 180.6 0.0 5.1e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 RJW65473.1 - 2.2e-18 66.1 0.0 4.7e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 RJW65473.1 - 2.2e-08 33.9 9.2 5.8e-08 32.5 9.2 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 RJW65473.1 - 0.00059 19.7 4.0 0.0013 18.6 4.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 ADK_lid PF05191.14 RJW65473.1 - 0.0044 17.0 0.2 0.0099 15.8 0.2 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid APH PF01636.23 RJW65473.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-HIT PF04438.16 RJW65474.1 - 8.4e-09 35.1 5.4 1.3e-08 34.5 5.4 1.3 1 0 0 1 1 1 1 HIT zinc finger PAPA-1 PF04795.12 RJW65474.1 - 2.4 9.0 9.9 0.76 10.6 6.4 2.1 2 1 0 2 2 2 0 PAPA-1-like conserved region zf-B_box PF00643.24 RJW65475.1 - 5.1e-07 29.7 4.0 1.5e-06 28.2 4.0 1.8 1 0 0 1 1 1 1 B-box zinc finger MATH PF00917.26 RJW65475.1 - 3e-06 27.4 0.0 8.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 MATH domain YabA PF06156.13 RJW65475.1 - 0.22 12.2 5.6 1.4 9.6 1.4 3.6 3 0 0 3 3 3 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 RJW65475.1 - 0.57 10.2 12.0 0.11 12.5 4.0 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Smg4_UPF3 PF03467.15 RJW65478.1 - 2e-39 135.4 0.1 3.3e-39 134.7 0.1 1.3 1 0 0 1 1 1 1 Smg-4/UPF3 family RVT_1 PF00078.27 RJW65478.1 - 2.2e-38 132.0 0.0 3.5e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LIAS_N PF16881.5 RJW65478.1 - 0.015 15.7 0.2 0.032 14.6 0.2 1.5 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family Nop PF01798.18 RJW65479.1 - 1.1e-58 198.4 0.2 2.6e-58 197.2 0.0 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Tup_N PF08581.10 RJW65480.1 - 0.0037 17.5 6.1 0.12 12.7 0.5 3.3 3 0 0 3 3 3 1 Tup N-terminal DASH_Dad3 PF08656.10 RJW65480.1 - 0.032 14.3 2.1 0.095 12.8 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 Syntaxin_2 PF14523.6 RJW65480.1 - 0.067 13.6 3.3 0.19 12.1 3.3 1.8 1 0 0 1 1 1 0 Syntaxin-like protein Filament PF00038.21 RJW65480.1 - 0.091 12.3 12.2 0.11 12.0 9.4 2.2 2 0 0 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 RJW65480.1 - 0.093 11.6 15.3 0.044 12.6 11.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 RJW65480.1 - 0.14 11.5 4.9 0.25 10.6 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 RJW65480.1 - 0.22 11.7 7.9 1.8 8.7 4.9 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 RJW65480.1 - 0.42 10.8 9.6 1.6 8.9 1.3 3.0 1 1 0 2 2 2 0 Tropomyosin like Efg1 PF10153.9 RJW65480.1 - 1.6 9.1 8.7 10 6.6 8.7 2.4 1 1 0 1 1 1 0 rRNA-processing protein Efg1 GAS PF13851.6 RJW65480.1 - 2 7.7 14.5 4 6.8 9.5 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 RJW65480.1 - 2.3 7.2 11.0 5.3 6.0 10.6 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 RJW65480.1 - 3.7 7.6 17.1 1.1 9.3 12.2 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 RJW65480.1 - 3.8 7.6 11.5 2.2 8.3 4.6 3.8 4 1 1 5 5 5 0 GDP/GTP exchange factor Sec2p HIP1_clath_bdg PF16515.5 RJW65480.1 - 8.8 7.0 14.0 5.6 7.7 9.5 3.0 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SKIP_SNW PF02731.15 RJW65481.1 - 2.6e-70 235.2 3.7 2.6e-70 235.2 3.7 3.1 3 0 0 3 3 3 1 SKIP/SNW domain MULE PF10551.9 RJW65481.1 - 0.031 14.7 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 MULE transposase domain Sial-lect-inser PF09264.10 RJW65482.1 - 0.19 11.5 0.0 20 4.9 0.0 2.0 1 1 1 2 2 2 0 Vibrio cholerae sialidase, lectin insertion zf-RING_2 PF13639.6 RJW65483.1 - 6.7e-10 39.1 8.7 6.7e-10 39.1 8.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 RJW65483.1 - 4.3e-08 32.7 5.0 1.4e-07 31.1 5.0 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RJW65483.1 - 3e-06 27.1 4.6 6.6e-06 26.1 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RJW65483.1 - 5.7e-06 26.1 8.7 1.3e-05 24.9 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW65483.1 - 7.1e-06 25.8 7.5 1.5e-05 24.7 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW65483.1 - 0.00014 21.7 5.0 0.00034 20.5 5.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RJW65483.1 - 0.00018 21.7 8.1 0.00018 21.7 8.1 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RJW65483.1 - 0.00049 19.9 6.3 0.0011 18.8 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RJW65483.1 - 0.006 16.2 5.2 0.012 15.2 5.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 RJW65483.1 - 0.0091 16.0 4.5 0.021 14.8 4.5 1.7 1 1 0 1 1 1 1 Zinc-finger Prok-RING_4 PF14447.6 RJW65483.1 - 0.21 11.5 5.8 0.44 10.4 5.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 RJW65483.1 - 0.47 10.4 7.0 0.4 10.6 3.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 RJW65483.1 - 5.9 7.1 13.2 3.5 7.9 8.6 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 RJW65483.1 - 7.2 7.0 7.7 58 4.1 0.0 2.5 2 1 0 2 2 2 0 RING-like domain Exo_endo_phos_2 PF14529.6 RJW65484.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase YabA PF06156.13 RJW65485.1 - 0.0024 18.5 21.9 0.29 11.8 4.4 4.0 1 1 3 4 4 4 3 Initiation control protein YabA DUF4407 PF14362.6 RJW65485.1 - 8 5.7 16.7 25 4.1 16.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PLAT PF01477.23 RJW65486.1 - 9.3e-06 26.2 0.4 7.2e-05 23.3 0.1 2.3 2 0 0 2 2 2 1 PLAT/LH2 domain Prp18 PF02840.15 RJW65489.1 - 4.4e-57 192.2 0.1 4.4e-57 192.2 0.1 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 RJW65489.1 - 6.4e-12 44.8 1.3 1.5e-11 43.6 1.3 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like BppU_IgG PF18667.1 RJW65489.1 - 0.061 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain GATA PF00320.27 RJW65492.1 - 3.8e-28 96.8 17.9 1.1e-14 53.7 4.8 2.9 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 RJW65492.1 - 6.3e-06 25.6 5.4 0.014 14.9 0.6 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 RJW65492.1 - 0.0053 16.8 14.2 0.044 13.9 0.5 3.4 2 1 1 3 3 3 2 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 RJW65492.1 - 0.051 13.5 8.4 1.1 9.2 0.8 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 RJW65492.1 - 0.068 13.0 5.8 1.5 8.7 0.7 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Elf1 PF05129.13 RJW65492.1 - 0.081 13.0 2.4 8.7 6.5 0.1 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 RJW65492.1 - 0.16 12.1 2.0 16 5.7 0.3 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 RJW65492.1 - 0.18 12.0 5.3 4.5 7.5 0.5 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 RJW65492.1 - 0.33 11.0 7.5 8.5 6.5 0.6 2.9 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_2 PF14445.6 RJW65492.1 - 3 8.1 6.3 0.43 10.8 0.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 tRNA-synt_2e PF02091.15 RJW65493.1 - 0.035 13.3 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit SH2 PF00017.24 RJW65494.1 - 4.8e-19 68.2 0.0 8e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 RJW65494.1 - 6.4e-15 54.7 0.1 1.3e-09 37.7 0.1 2.6 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 RJW65494.1 - 9.5e-14 50.7 0.2 6.3e-10 38.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 RJW65494.1 - 3.7e-10 39.3 0.0 6.1e-07 29.0 0.0 2.8 2 1 0 2 2 2 2 Variant SH3 domain CesT PF05932.13 RJW65494.1 - 0.19 11.8 0.0 0.62 10.2 0.0 1.8 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family MlaA PF04333.13 RJW65495.1 - 0.19 11.4 0.2 0.29 10.8 0.1 1.3 1 1 0 1 1 1 0 MlaA lipoprotein Med7 PF05983.11 RJW65496.1 - 1e-26 94.2 1.5 1.8e-26 93.4 0.9 1.6 2 0 0 2 2 2 1 MED7 protein EppA_BapA PF07268.11 RJW65496.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) Zip PF02535.22 RJW65498.1 - 2.7e-24 86.0 6.5 4.9e-24 85.2 6.5 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4203 PF13886.6 RJW65498.1 - 0.0072 16.0 13.5 0.37 10.4 1.9 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4203) HEAT PF02985.22 RJW65500.1 - 0.0019 18.3 3.3 1.3 9.5 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 RJW65500.1 - 0.0034 17.4 5.9 3.5 7.7 0.1 5.4 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RJW65500.1 - 0.019 15.4 0.1 0.44 11.0 0.1 3.0 2 1 0 2 2 2 0 HEAT repeats Nif11 PF07862.11 RJW65500.1 - 0.031 14.6 0.0 0.085 13.2 0.0 1.8 1 0 0 1 1 1 0 Nif11 domain Adaptin_N PF01602.20 RJW65500.1 - 0.067 11.7 4.9 0.1 11.1 0.3 3.0 2 1 0 3 3 3 0 Adaptin N terminal region AT_hook PF02178.19 RJW65500.1 - 0.31 11.0 3.2 1 9.5 3.2 2.0 1 0 0 1 1 1 0 AT hook motif MLTD_N PF06474.12 RJW65500.1 - 0.36 11.0 1.6 2.1 8.6 1.6 2.3 1 0 0 1 1 1 0 MltD lipid attachment motif MULE PF10551.9 RJW65501.1 - 0.0017 18.7 0.0 0.0036 17.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 RJW65501.1 - 0.031 15.0 0.1 0.06 14.0 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain DpnI_C PF17726.1 RJW65501.1 - 0.057 13.6 0.2 0.13 12.4 0.1 1.6 2 0 0 2 2 2 0 Dam-replacing HTH domain FimA PF16970.5 RJW65503.1 - 0.072 13.3 0.1 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 Type-1 fimbrial protein, A PI3K_P85_iSH2 PF16454.5 RJW65504.1 - 0.0023 17.5 13.4 0.024 14.2 3.7 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 RJW65504.1 - 0.07 12.0 10.8 0.1 11.4 10.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 RJW65504.1 - 0.69 8.9 8.8 1.1 8.2 8.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 RJW65504.1 - 2.9 7.4 6.5 4.8 6.7 6.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS5 PF14817.6 RJW65504.1 - 6.3 5.4 13.5 32 3.1 13.6 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 Phlebovirus_NSM PF07246.11 RJW65504.1 - 6.6 6.0 6.8 14 5.0 6.8 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M SlyX PF04102.12 RJW65504.1 - 6.8 7.4 11.8 4.1 8.1 2.0 3.1 2 1 1 3 3 3 0 SlyX V_ATPase_I PF01496.19 RJW65504.1 - 9.1 4.0 9.0 12 3.6 9.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family G-gamma PF00631.22 RJW65506.1 - 0.00028 20.8 0.2 0.00045 20.2 0.2 1.3 1 0 0 1 1 1 1 GGL domain I_LWEQ PF01608.17 RJW65507.1 - 3.7e-44 150.6 2.7 3.7e-44 150.6 2.7 3.4 3 1 0 3 3 3 1 I/LWEQ domain ANTH PF07651.16 RJW65507.1 - 5e-41 140.5 0.1 1.8e-40 138.7 0.0 2.0 2 0 0 2 2 2 1 ANTH domain GIT1_C PF12205.8 RJW65507.1 - 0.77 9.9 5.1 18 5.5 0.3 3.3 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term PIN_6 PF17146.4 RJW65507.1 - 1.1 9.8 3.8 1.4 9.4 0.7 2.7 3 0 0 3 3 3 0 PIN domain of ribonuclease Pkinase PF00069.25 RJW65510.1 - 1.5e-56 191.7 0.0 1.7e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW65510.1 - 5.6e-28 97.9 0.0 6.8e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW65510.1 - 8e-05 21.6 0.0 9.9e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_1 PF00036.32 RJW65511.1 - 7.9e-22 75.1 12.2 1.7e-08 33.4 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW65511.1 - 5e-20 71.7 10.9 6.3e-10 39.4 2.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW65511.1 - 1.4e-18 65.5 10.7 3.7e-07 29.3 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RJW65511.1 - 2.6e-17 61.2 10.7 6.8e-07 28.7 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RJW65511.1 - 2.6e-11 43.2 9.1 0.00011 22.0 0.1 4.1 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW65511.1 - 7.7e-07 29.4 7.5 9.4e-05 22.7 0.4 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Staphylokinase PF02821.16 RJW65511.1 - 0.0031 17.9 0.3 0.0066 16.9 0.2 1.6 2 0 0 2 2 2 1 Staphylokinase/Streptokinase family EF-hand_10 PF14788.6 RJW65511.1 - 0.01 15.6 4.5 0.29 11.0 0.1 2.8 3 0 0 3 3 3 0 EF hand Caleosin PF05042.13 RJW65511.1 - 0.035 14.0 1.0 7.3 6.5 0.1 3.1 1 1 2 3 3 3 0 Caleosin related protein EF-hand_9 PF14658.6 RJW65511.1 - 0.05 13.9 0.0 6.6 7.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_13 PF17958.1 RJW65511.1 - 0.093 12.5 0.0 0.59 10.0 0.0 2.2 2 1 0 2 2 2 0 EF-hand domain Evr1_Alr PF04777.13 RJW65511.1 - 0.2 12.1 1.1 0.9 10.1 1.0 1.9 1 1 0 1 1 1 0 Erv1 / Alr family F-box-like PF12937.7 RJW65513.1 - 6.8e-05 22.7 0.1 6.8e-05 22.7 0.1 3.1 3 0 0 3 3 3 1 F-box-like Sec7_N PF12783.7 RJW65513.1 - 0.043 13.7 0.6 0.099 12.5 0.6 1.5 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal F-box_5 PF18511.1 RJW65513.1 - 0.071 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 F-box NifQ PF04891.12 RJW65513.1 - 0.072 13.4 0.3 0.19 12.1 0.3 1.8 1 0 0 1 1 1 0 NifQ RRM_1 PF00076.22 RJW65514.1 - 7.6e-34 115.4 0.2 3.2e-09 36.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 RJW65514.1 - 0.00079 17.8 22.5 0.00079 17.8 22.5 2.1 2 0 0 2 2 2 2 Nop14-like family BUD22 PF09073.10 RJW65514.1 - 0.23 10.8 73.6 0.25 10.6 32.3 2.2 2 0 0 2 2 2 0 BUD22 Med7 PF05983.11 RJW65516.1 - 2.5e-07 31.0 2.2 1e-06 29.0 2.2 1.8 1 1 0 1 1 1 1 MED7 protein MORN PF02493.20 RJW65520.1 - 2.7e-28 96.1 43.4 1.1e-05 25.0 0.3 9.1 9 0 0 9 9 9 7 MORN repeat TMEM132 PF16070.5 RJW65522.1 - 6.1e-19 68.6 0.0 3.1e-18 66.2 0.0 2.1 3 0 0 3 3 3 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 RJW65522.1 - 6.7e-07 29.0 0.1 4e-06 26.5 0.1 2.3 1 1 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Cyclin_N PF00134.23 RJW65523.1 - 5.7e-15 55.2 0.1 8.6e-15 54.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glycolytic PF00274.19 RJW65525.1 - 4.9e-169 561.6 0.0 6e-169 561.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I LRR_8 PF13855.6 RJW65526.1 - 6.3e-39 131.5 21.8 2.6e-11 43.1 0.4 6.5 5 1 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 RJW65526.1 - 3.2e-14 52.8 17.0 3e-05 24.3 0.5 6.3 4 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RJW65526.1 - 1.1e-11 44.8 0.0 3.7e-06 26.9 0.0 3.5 3 2 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RJW65526.1 - 2.1e-08 33.6 20.6 0.55 11.0 0.1 8.9 8 2 1 9 9 9 3 Leucine Rich Repeat LRR_9 PF14580.6 RJW65526.1 - 0.0021 17.6 4.0 0.83 9.1 0.2 3.3 2 1 1 3 3 3 2 Leucine-rich repeat Chromadorea_ALT PF05535.12 RJW65526.1 - 0.014 15.6 0.6 0.032 14.4 0.6 1.6 1 0 0 1 1 1 0 Chromadorea ALT protein LRR_6 PF13516.6 RJW65526.1 - 0.054 13.6 22.3 3.4 8.0 0.1 7.7 9 0 0 9 9 9 0 Leucine Rich repeat PRIMA1 PF16101.5 RJW65526.1 - 0.14 12.2 0.1 0.14 12.2 0.1 2.1 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 PAP2 PF01569.21 RJW65527.1 - 2.3e-16 59.8 6.1 2.3e-16 59.8 6.1 1.8 2 0 0 2 2 2 1 PAP2 superfamily RVT_1 PF00078.27 RJW65527.1 - 1.7e-08 34.3 0.0 3.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 RJW65527.1 - 0.016 15.4 0.1 0.033 14.5 0.1 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain BC10 PF06726.12 RJW65527.1 - 0.052 13.8 1.1 0.16 12.2 0.1 2.3 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 Tox-PL-2 PF15643.6 RJW65527.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Papain fold toxin 2 Cellulase PF00150.18 RJW65529.1 - 2e-31 109.4 0.7 2.9e-31 109.0 0.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 RJW65529.1 - 4.9e-08 33.4 0.0 1.1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain HpuA PF16960.5 RJW65529.1 - 0.029 13.5 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter Herpes_UL52 PF03121.15 RJW65532.1 - 0.035 14.0 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase tRNA_m1G_MT PF01746.21 RJW65533.1 - 2.9e-09 36.9 0.0 5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Oxysterol_BP PF01237.18 RJW65534.1 - 9.1e-77 258.4 0.0 1.8e-74 250.9 0.0 2.3 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 RJW65534.1 - 3.8e-14 53.1 0.1 7.3e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RJW65534.1 - 6.4e-08 32.8 0.5 1.5e-07 31.6 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 RJW65534.1 - 1.5e-05 25.4 3.7 0.00021 21.7 3.7 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 RJW65534.1 - 0.00078 19.7 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 RJW65534.1 - 0.008 16.0 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 RJW65534.1 - 0.015 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 PH domain PH PF00169.29 RJW65535.1 - 6.8e-07 29.8 0.0 1.6e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 PH domain JAKMIP_CC3 PF16034.5 RJW65535.1 - 0.031 14.2 4.9 0.028 14.4 2.0 2.4 2 0 0 2 2 2 0 JAKMIP CC3 domain DUF5641 PF18701.1 RJW65536.1 - 8.2e-31 106.0 2.6 3.1e-30 104.2 2.6 2.1 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Peptidase_A17 PF05380.13 RJW65536.1 - 7.6e-30 104.0 0.0 2.4e-29 102.4 0.0 1.9 1 0 0 1 1 1 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 RJW65536.1 - 1.7e-08 34.4 1.7 5.5e-08 32.8 1.7 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RJW65536.1 - 9.7e-08 32.2 0.0 2.5e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 RJW65536.1 - 0.0002 21.0 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TetR_C_27 PF17935.1 RJW65536.1 - 0.076 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain gag-asp_proteas PF13975.6 RJW65536.1 - 0.12 12.9 0.0 0.48 11.0 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1759 PF03564.15 RJW65536.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) PALP PF00291.25 RJW65539.1 - 2.2e-74 250.5 1.7 2.7e-74 250.2 1.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 RJW65539.1 - 1.2e-05 24.9 0.0 2.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain BSD PF03909.17 RJW65540.1 - 0.018 15.0 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 BSD domain Adhesin_P1 PF03257.13 RJW65540.1 - 0.065 13.8 0.8 12 6.5 0.0 3.7 4 0 0 4 4 4 0 Mycoplasma adhesin P1 DUF226 PF02890.14 RJW65541.1 - 0.0014 18.6 0.8 0.0025 17.9 0.8 1.4 1 0 0 1 1 1 1 Borrelia family of unknown function DUF226 DUF3719 PF12516.8 RJW65542.1 - 1.8e-07 30.7 1.4 5.3e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3719) zf-C2H2_4 PF13894.6 RJW65543.1 - 6.7e-05 23.4 34.8 0.04 14.8 2.5 5.0 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW65543.1 - 0.00067 20.0 25.5 0.069 13.6 2.5 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-FPG_IleRS PF06827.14 RJW65543.1 - 0.015 15.1 2.8 0.14 12.0 0.5 2.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-CSL PF05207.13 RJW65543.1 - 0.58 9.9 8.0 0.19 11.5 2.6 2.7 3 0 0 3 3 3 0 CSL zinc finger zf-C2H2_jaz PF12171.8 RJW65543.1 - 0.87 9.9 5.7 7.5 7.0 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 RJW65543.1 - 5.3 7.1 7.4 11 6.0 0.5 3.1 3 0 0 3 3 3 0 CpXC protein zf_UBZ PF18439.1 RJW65543.1 - 5.9 6.6 6.5 3.2 7.4 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF3449 PF11931.8 RJW65543.1 - 6.1 6.6 7.0 5.3 6.8 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) APG5 PF04106.12 RJW65544.1 - 5.2e-50 170.2 0.1 7.3e-50 169.7 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 OAM_alpha PF16552.5 RJW65544.1 - 0.034 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit Pkinase_Tyr PF07714.17 RJW65546.1 - 4.9e-74 248.9 0.0 2.7e-71 239.9 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW65546.1 - 4.6e-32 111.4 0.0 2.6e-31 109.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GF_recep_IV PF14843.6 RJW65546.1 - 4.6e-17 62.0 69.4 5.5e-08 32.7 11.8 5.3 2 1 2 5 5 5 4 Growth factor receptor domain IV Furin-like PF00757.20 RJW65546.1 - 2.2e-08 34.1 73.2 2.1e-06 27.7 10.4 5.2 1 1 3 5 5 5 3 Furin-like cysteine rich region Kinase-like PF14531.6 RJW65546.1 - 0.029 13.7 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RJW65546.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RJW65546.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_primase_S PF01896.19 RJW65546.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 DNA primase small subunit Pkinase_fungal PF17667.1 RJW65546.1 - 0.17 10.6 0.0 0.38 9.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase PP2C PF00481.21 RJW65547.1 - 1.5e-25 90.3 0.0 1.5e-24 87.1 0.0 2.2 2 1 0 2 2 2 1 Protein phosphatase 2C DUF572 PF04502.13 RJW65548.1 - 6.8e-76 256.0 0.1 1.1e-75 255.4 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) RVT_1 PF00078.27 RJW65548.1 - 1.2e-32 113.2 0.0 2.3e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW65548.1 - 7.7e-07 29.0 0.0 2.2e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Scramblase PF03803.15 RJW65551.1 - 1.3e-27 96.6 0.0 1.7e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Scramblase EF-hand_1 PF00036.32 RJW65552.1 - 1.2e-34 115.2 13.4 3.1e-07 29.4 0.6 6.4 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 RJW65552.1 - 3.6e-32 107.5 11.0 1.3e-06 27.8 0.1 6.4 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.6 RJW65552.1 - 3e-26 91.6 21.7 4.7e-11 43.0 1.4 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW65552.1 - 1.4e-20 71.8 19.1 0.00016 21.0 0.0 6.4 6 0 0 6 6 6 6 EF hand EF-hand_8 PF13833.6 RJW65552.1 - 4.7e-09 36.0 6.9 0.0088 15.9 0.1 5.6 5 1 0 5 5 5 3 EF-hand domain pair GPHH PF16905.5 RJW65552.1 - 1e-06 28.4 0.1 0.014 15.2 0.0 2.6 2 0 0 2 2 2 2 Voltage-dependent L-type calcium channel, IQ-associated Dockerin_1 PF00404.18 RJW65552.1 - 0.0018 18.5 0.3 0.52 10.6 0.0 4.0 4 0 0 4 4 4 1 Dockerin type I domain EF-hand_10 PF14788.6 RJW65552.1 - 0.0048 16.7 8.5 1.2 9.0 0.1 4.9 5 0 0 5 5 5 1 EF hand UPF0149 PF03695.13 RJW65552.1 - 0.0068 16.7 2.2 1.3 9.3 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0149) EF-hand_9 PF14658.6 RJW65552.1 - 0.016 15.5 0.0 2.5 8.5 0.0 3.3 2 2 1 3 3 3 0 EF-hand domain p25-alpha PF05517.12 RJW65552.1 - 0.2 11.8 2.2 2.4 8.3 0.0 2.9 3 1 0 3 3 3 0 p25-alpha Caleosin PF05042.13 RJW65552.1 - 0.25 11.2 6.4 35 4.3 0.1 4.6 3 2 0 4 4 4 0 Caleosin related protein EF-hand_6 PF13405.6 RJW65554.1 - 1e-11 43.7 6.4 0.26 11.3 0.2 7.5 7 0 0 7 7 7 3 EF-hand domain EF-hand_7 PF13499.6 RJW65554.1 - 1.8e-11 44.3 7.4 0.67 10.5 0.3 7.7 7 1 1 8 8 8 4 EF-hand domain pair EF-hand_1 PF00036.32 RJW65554.1 - 5.3e-05 22.5 0.3 0.38 10.4 0.0 5.2 5 0 0 5 5 5 1 EF hand RST PF12174.8 RJW65554.1 - 0.00027 20.8 0.1 3.1 7.8 0.0 5.6 5 1 1 6 6 6 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_8 PF13833.6 RJW65554.1 - 0.00053 19.8 0.0 4.4 7.2 0.0 4.8 4 0 0 4 4 4 1 EF-hand domain pair Ras PF00071.22 RJW65555.1 - 6.4e-20 71.4 0.1 2.9e-14 53.0 0.1 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RJW65555.1 - 5.7e-06 26.6 0.1 0.0092 16.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RJW65555.1 - 2.4e-05 24.4 0.1 6.7e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 RJW65555.1 - 3.8e-05 23.2 0.4 0.074 12.5 0.4 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.18 RJW65555.1 - 0.0011 18.6 0.2 0.14 11.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 RJW65555.1 - 0.0029 17.1 0.7 1.9 7.9 0.0 2.4 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA PF00004.29 RJW65555.1 - 0.02 15.3 0.5 0.69 10.4 0.5 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RJW65555.1 - 0.022 15.3 0.1 0.071 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RJW65555.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Recep_L_domain PF01030.24 RJW65556.1 - 5e-22 78.1 0.1 3.7e-12 46.4 0.0 2.6 2 0 0 2 2 2 2 Receptor L domain Furin-like PF00757.20 RJW65556.1 - 5.4e-16 58.8 34.6 9.4e-16 58.0 34.6 1.4 1 0 0 1 1 1 1 Furin-like cysteine rich region GF_recep_IV PF14843.6 RJW65556.1 - 0.0016 18.3 36.5 0.14 11.9 7.4 3.8 1 1 3 4 4 4 2 Growth factor receptor domain IV NDC10_II PF16787.5 RJW65556.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 RhoGAP PF00620.27 RJW65558.1 - 9.4e-34 116.4 0.0 2.5e-33 115.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.18 RJW65558.1 - 6.6e-06 25.9 10.2 1.5e-05 24.8 10.2 1.6 1 1 0 1 1 1 1 BAR domain Fib_alpha PF08702.10 RJW65558.1 - 0.99 9.6 5.2 0.76 10.0 2.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Kinesin PF00225.23 RJW65559.1 - 1.3e-79 267.6 0.1 2.2e-78 263.5 0.1 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RJW65559.1 - 3.7e-46 156.8 0.0 1.2e-45 155.1 0.0 1.9 1 1 0 1 1 1 1 Microtubule binding Holin_BhlA PF10960.8 RJW65559.1 - 0.0023 17.9 3.0 0.0071 16.3 0.3 2.5 2 0 0 2 2 2 1 BhlA holin family TRAP_beta PF05753.14 RJW65559.1 - 0.21 11.0 0.0 0.41 10.0 0.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) Lzipper-MIP1 PF14389.6 RJW65559.1 - 0.61 10.4 6.1 0.11 12.9 1.0 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 7tm_2 PF00002.24 RJW65562.1 - 2.2e-07 30.4 1.2 2.5e-07 30.3 1.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 RJW65564.1 - 1.3e-12 47.8 1.7 2e-12 47.2 1.0 1.7 2 0 0 2 2 2 1 Hormone receptor domain 7tm_2 PF00002.24 RJW65564.1 - 1e-08 34.8 8.4 1.4e-08 34.4 8.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pkinase PF00069.25 RJW65565.1 - 5.1e-21 75.2 0.0 7.1e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW65565.1 - 4.8e-16 58.8 0.0 1.1e-15 57.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW65565.1 - 0.005 15.7 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase ABC_tran PF00005.27 RJW65566.1 - 8.3e-46 155.9 0.1 9.1e-23 81.3 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 RJW65566.1 - 1.3e-25 89.2 2.2 2.4e-25 88.4 2.2 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RJW65566.1 - 5.8e-20 72.3 0.4 2.5e-06 27.6 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RJW65566.1 - 3e-10 39.9 0.3 0.00077 19.0 0.0 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RJW65566.1 - 3.1e-08 34.3 0.9 0.0041 17.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 RJW65566.1 - 1.6e-06 28.1 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 RJW65566.1 - 3.8e-06 26.8 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 RJW65566.1 - 5.9e-06 26.8 0.9 0.0049 17.3 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 RJW65566.1 - 6.6e-06 26.4 1.0 0.01 16.1 0.1 3.3 2 2 0 2 2 2 1 AAA domain NACHT PF05729.12 RJW65566.1 - 6.9e-06 26.1 0.0 0.04 13.8 0.0 3.3 3 0 0 3 3 3 2 NACHT domain AAA_29 PF13555.6 RJW65566.1 - 4.5e-05 23.1 0.1 0.092 12.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 RJW65566.1 - 5.6e-05 23.3 0.4 0.98 9.6 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 RJW65566.1 - 7.4e-05 23.0 0.3 0.67 10.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain MobB PF03205.14 RJW65566.1 - 9.4e-05 22.3 0.0 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 RJW65566.1 - 0.00016 21.7 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 RJW65566.1 - 0.00034 20.8 0.0 0.32 11.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 RJW65566.1 - 0.0006 20.4 0.2 0.92 10.1 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 RJW65566.1 - 0.00097 18.9 0.0 0.49 10.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain TsaE PF02367.17 RJW65566.1 - 0.002 18.2 0.1 0.28 11.2 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 RJW65566.1 - 0.002 18.3 0.5 0.29 11.4 0.1 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 RJW65566.1 - 0.0021 17.8 0.0 0.23 11.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 RJW65566.1 - 0.0022 17.5 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region PduV-EutP PF10662.9 RJW65566.1 - 0.0026 17.5 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 RJW65566.1 - 0.0026 17.4 0.1 0.44 10.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 RJW65566.1 - 0.0029 18.0 0.0 2.9 8.3 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 RJW65566.1 - 0.0058 16.3 0.1 5.6 6.5 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 RJW65566.1 - 0.0092 16.4 0.0 1.2 9.5 0.0 3.1 4 0 0 4 4 2 1 RNA helicase T2SSE PF00437.20 RJW65566.1 - 0.011 14.8 0.0 0.031 13.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 RJW65566.1 - 0.013 15.6 0.0 1.9 8.5 0.0 3.2 3 0 0 3 3 3 0 Dynamin family DUF2813 PF11398.8 RJW65566.1 - 0.02 14.2 0.2 3.6 6.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) Arf PF00025.21 RJW65566.1 - 0.02 14.4 0.0 0.59 9.6 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family NTPase_1 PF03266.15 RJW65566.1 - 0.033 14.1 0.0 3.1 7.7 0.0 3.0 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 RJW65566.1 - 0.043 13.0 0.0 9.3 5.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 RJW65566.1 - 0.044 13.8 0.2 4.2 7.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 RJW65566.1 - 0.046 12.4 1.2 1.4 7.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 RJW65566.1 - 0.05 13.2 0.0 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 RJW65566.1 - 0.059 13.0 0.0 8.5 6.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.12 RJW65566.1 - 0.075 12.5 0.3 0.92 8.9 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Septin PF00735.18 RJW65566.1 - 0.083 12.2 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Septin Bac_DnaA PF00308.18 RJW65566.1 - 0.11 12.3 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein DUF3584 PF12128.8 RJW65566.1 - 0.12 9.8 0.0 0.12 9.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) DLIC PF05783.11 RJW65566.1 - 0.14 11.0 0.2 0.35 9.7 0.0 1.7 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) BACK PF07707.15 RJW65568.1 - 6.1e-06 26.3 0.2 2.8e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 RJW65568.1 - 1e-05 25.7 0.7 0.00029 21.0 0.7 2.8 1 1 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 RJW65570.1 - 7e-21 74.2 8.2 0.00026 21.7 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW65570.1 - 3.6e-08 33.6 0.0 0.00015 21.9 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW65570.1 - 0.001 17.8 0.2 0.11 11.1 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RJW65570.1 - 0.011 14.7 0.0 1.8 7.5 0.0 2.6 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Neur_chan_LBD PF02931.23 RJW65571.1 - 2.5e-29 102.3 0.8 3.3e-29 101.9 0.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW65571.1 - 5.6e-20 72.4 3.3 8.7e-18 65.2 3.2 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region RT_RNaseH_2 PF17919.1 RJW65572.1 - 9.7e-10 38.4 0.1 1.5e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW65572.1 - 0.029 14.7 0.1 0.057 13.7 0.1 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase ATG_C PF09333.11 RJW65573.1 - 1.9e-23 82.6 0.0 7.7e-23 80.7 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 RJW65573.1 - 0.00081 19.1 0.1 0.0019 18.0 0.1 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 RJW65573.1 - 0.0013 18.6 0.2 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal BIR PF00653.21 RJW65574.1 - 6.4e-20 71.6 4.7 6.4e-20 71.6 4.7 1.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain DUF3504 PF12012.8 RJW65575.1 - 6.9e-31 107.4 0.3 3e-22 79.3 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF3504) Metaviral_G PF09595.10 RJW65576.1 - 0.16 12.0 2.3 0.26 11.3 0.4 1.9 1 1 1 2 2 2 0 Metaviral_G glycoprotein CTP_transf_like PF01467.26 RJW65578.1 - 3e-37 128.0 0.0 8.4e-18 64.9 0.0 3.8 3 1 0 3 3 3 2 Cytidylyltransferase-like FAD_syn PF06574.12 RJW65578.1 - 0.02 14.8 2.5 9.7 6.1 0.0 3.7 3 1 0 3 3 3 0 FAD synthetase Pkinase PF00069.25 RJW65579.1 - 7.3e-72 241.9 0.0 1.2e-71 241.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW65579.1 - 4.6e-31 108.0 0.0 7.3e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW65579.1 - 1.3e-06 27.7 0.0 2.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RJW65579.1 - 0.0031 16.9 0.0 0.0088 15.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like UL97 PF06734.12 RJW65580.1 - 0.012 15.6 0.1 5.9 6.7 0.0 2.3 2 0 0 2 2 2 0 UL97 Pkinase_Tyr PF07714.17 RJW65581.1 - 1.1e-91 306.7 0.0 1.7e-91 306.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW65581.1 - 2.9e-43 148.1 0.0 4.4e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RJW65581.1 - 2.3e-21 75.7 0.2 4.6e-21 74.7 0.2 1.5 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 RJW65581.1 - 8.5e-09 35.1 0.0 2.1e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RJW65581.1 - 6.3e-08 32.1 0.0 1.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RJW65581.1 - 8.3e-08 31.8 0.0 1.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 RJW65581.1 - 0.00047 20.1 0.0 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW65581.1 - 0.0027 16.7 0.0 0.0048 15.9 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain SH3_10 PF17902.1 RJW65581.1 - 0.0033 17.4 0.0 0.013 15.6 0.0 2.1 1 0 0 1 1 1 1 SH3 domain Kinase-like PF14531.6 RJW65581.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 RJW65581.1 - 0.017 14.7 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 RJW65581.1 - 0.055 12.8 0.1 0.13 11.6 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 RJW65582.1 - 5.6e-29 100.8 0.1 6.7e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW65582.1 - 3e-11 43.6 0.0 6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 RJW65582.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Arf PF00025.21 RJW65582.1 - 0.17 11.3 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family SPT2 PF08243.11 RJW65583.1 - 4.2e-15 56.2 14.0 4.2e-15 56.2 14.0 1.5 2 0 0 2 2 2 1 SPT2 chromatin protein HUN PF08729.10 RJW65583.1 - 0.0025 17.8 7.4 0.0055 16.7 7.4 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain I_LWEQ PF01608.17 RJW65583.1 - 0.8 9.9 5.9 0.1 12.8 0.8 1.9 2 0 0 2 2 2 0 I/LWEQ domain RT_RNaseH_2 PF17919.1 RJW65585.1 - 1.7e-38 130.7 0.0 3.3e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW65585.1 - 5.5e-35 119.8 0.0 1.1e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW65585.1 - 8.6e-24 84.3 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RJW65585.1 - 2.3e-22 79.4 0.0 5.2e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW65585.1 - 8.8e-18 64.2 0.3 8.8e-18 64.2 0.3 2.5 3 0 0 3 3 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RJW65585.1 - 9.6e-06 25.7 0.1 9.6e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 RJW65585.1 - 7.4e-05 22.5 0.0 0.00019 21.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 RJW65585.1 - 0.0032 18.0 0.0 0.007 16.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 RJW65585.1 - 0.026 14.8 0.0 0.068 13.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 RJW65585.1 - 0.056 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease MU117 PF15474.6 RJW65585.1 - 0.54 11.1 4.4 7.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Meiotically up-regulated gene family zf-CCHC PF00098.23 RJW65585.1 - 0.58 10.3 9.3 0.62 10.3 0.8 3.0 2 0 0 2 2 2 0 Zinc knuckle HypA PF01155.19 RJW65585.1 - 1.6 8.8 4.8 2.3 8.3 2.4 2.5 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CCHC_2 PF13696.6 RJW65585.1 - 7.8 6.4 8.5 0.2 11.5 1.3 2.2 2 0 0 2 2 1 0 Zinc knuckle Prefoldin PF02996.17 RJW65586.1 - 0.049 13.5 0.1 0.049 13.5 0.1 5.0 5 0 0 5 5 5 0 Prefoldin subunit Filament PF00038.21 RJW65586.1 - 0.11 12.1 48.4 0.21 11.1 20.5 3.6 2 1 1 3 3 3 0 Intermediate filament protein FlaC_arch PF05377.11 RJW65586.1 - 6.1 7.3 19.3 11 6.5 0.2 5.5 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF4860 PF16152.5 RJW65588.1 - 0.17 11.8 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4860) fn3 PF00041.21 RJW65589.1 - 0.0022 18.3 0.2 0.14 12.5 0.0 3.2 3 0 0 3 3 3 1 Fibronectin type III domain PDZ_6 PF17820.1 RJW65590.1 - 4.3e-14 52.1 0.1 9.6e-14 51.0 0.1 1.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 RJW65590.1 - 1.2e-10 41.6 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW65590.1 - 4e-06 27.1 0.1 6.2e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 PDZ domain ASH PF15780.5 RJW65591.1 - 0.0038 17.4 0.0 4.8 7.5 0.0 3.6 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RJW65591.1 - 0.015 15.2 0.0 5.5 6.9 0.0 3.1 3 0 0 3 3 3 0 MSP (Major sperm protein) domain Band_7 PF01145.25 RJW65592.1 - 2.4e-25 89.5 0.4 3.8e-25 88.9 0.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family ODAM PF15424.6 RJW65592.1 - 0.03 13.9 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family DAGK_cat PF00781.24 RJW65592.1 - 0.086 12.5 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Dpy19 PF10034.9 RJW65592.1 - 0.1 10.7 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation YdfA_immunity PF12127.8 RJW65592.1 - 0.14 11.2 0.5 0.21 10.6 0.5 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial tRNA-synt_2 PF00152.20 RJW65595.1 - 1.1e-77 261.2 0.0 1.5e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 RJW65595.1 - 6.2e-10 39.0 0.1 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 RJW65595.1 - 1.1e-09 38.1 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ApbA_C PF08546.11 RJW65595.1 - 0.024 14.9 0.1 0.6 10.3 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DUF3835 PF12927.7 RJW65595.1 - 0.15 13.0 0.1 4.6 8.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) CUB PF00431.20 RJW65599.1 - 6.3e-15 55.5 0.0 1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 CUB domain C2-set_2 PF08205.12 RJW65599.1 - 0.046 13.8 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain ANAPC8 PF04049.13 RJW65600.1 - 0.00018 21.6 0.0 1.3 9.1 0.0 2.9 2 2 0 2 2 2 2 Anaphase promoting complex subunit 8 / Cdc23 Neural_ProG_Cyt PF06567.11 RJW65600.1 - 0.11 12.7 0.2 28 5.0 0.0 2.6 2 0 0 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain MNNL PF07657.13 RJW65600.1 - 0.58 10.2 6.6 11 6.2 0.7 2.8 2 0 0 2 2 2 0 N terminus of Notch ligand DUF4518 PF15008.6 RJW65600.1 - 1.8 7.7 5.3 14 4.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) DTW PF03942.15 RJW65601.1 - 0.18 11.5 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 DTW domain Ist1 PF03398.14 RJW65602.1 - 1.9e-55 187.3 3.8 2.6e-55 186.8 3.8 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway THEG PF14912.6 RJW65602.1 - 0.036 14.5 0.0 0.082 13.4 0.0 1.6 1 0 0 1 1 1 0 Testicular haploid expressed repeat DUF2569 PF10754.9 RJW65603.1 - 0.028 14.9 0.7 0.04 14.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) CENP-B_dimeris PF09026.10 RJW65603.1 - 0.91 10.0 9.9 1.4 9.3 9.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 RJW65603.1 - 5 7.4 7.4 8.4 6.7 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 RJW65603.1 - 6.2 6.5 11.4 8.9 6.0 11.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sod_Cu PF00080.20 RJW65604.1 - 3.9e-48 163.2 5.7 7.3e-48 162.3 5.7 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 RJW65604.1 - 0.055 14.4 2.1 0.093 13.7 2.1 1.5 1 1 0 1 1 1 0 CHRD domain SSF PF00474.17 RJW65606.1 - 8.4e-33 113.8 11.9 1.3e-32 113.2 11.9 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family FERM_N PF09379.10 RJW65607.1 - 3.8e-18 65.2 0.0 7.7e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain RVT_1 PF00078.27 RJW65608.1 - 1.3e-17 64.1 0.0 2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M24 PF00557.24 RJW65609.1 - 4.6e-53 180.0 0.0 7e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RJW65609.1 - 3.8e-19 68.6 0.0 8.2e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Cullin PF00888.22 RJW65610.1 - 5.9e-22 78.0 0.2 1e-21 77.2 0.2 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 RJW65610.1 - 9.1e-21 74.1 0.2 3e-20 72.5 0.1 2.0 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 DUF3752 PF12572.8 RJW65610.1 - 3.9e-09 37.2 18.7 3.2e-07 31.0 18.7 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3752) DUF2464 PF10240.9 RJW65610.1 - 0.017 14.7 0.6 0.017 14.7 0.6 2.1 2 0 0 2 2 2 0 Multivesicular body subunit 12 Rxt3 PF08642.10 RJW65610.1 - 2 9.2 6.4 0.73 10.6 1.6 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 NARP1 PF12569.8 RJW65610.1 - 2.4 7.0 17.2 4 6.2 17.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Borrelia_P83 PF05262.11 RJW65610.1 - 9.4 4.6 12.4 14 4.0 12.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein BLF1 PF17752.1 RJW65611.1 - 0.065 12.5 0.1 0.093 12.0 0.1 1.2 1 0 0 1 1 1 0 Burkholderia lethal factor 1 Sod_Fe_C PF02777.18 RJW65612.1 - 2.7e-36 123.8 0.1 5.5e-36 122.8 0.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 RJW65612.1 - 8.8e-32 109.4 1.7 1.4e-31 108.8 1.7 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Rhomboid PF01694.22 RJW65614.1 - 0.08 12.9 0.8 0.12 12.4 0.8 1.3 1 0 0 1 1 1 0 Rhomboid family Dynactin_p62 PF05502.13 RJW65617.1 - 0.14 10.9 5.7 1.4 7.6 6.2 1.9 2 0 0 2 2 2 0 Dynactin p62 family BUD22 PF09073.10 RJW65617.1 - 1.3 8.2 25.0 1.8 7.9 25.0 1.2 1 0 0 1 1 1 0 BUD22 DUF1704 PF08014.11 RJW65618.1 - 1.1e-07 31.2 0.1 2.7e-07 30.0 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1704) Peptidase_S3 PF00944.19 RJW65619.1 - 0.14 12.0 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Alphavirus core protein DZR PF12773.7 RJW65620.1 - 0.013 15.5 2.0 0.038 14.0 2.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 RJW65620.1 - 0.026 13.9 2.0 0.083 12.3 2.0 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RJW65620.1 - 0.079 13.7 2.4 0.19 12.5 2.4 1.7 1 0 0 1 1 1 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 RJW65620.1 - 1 9.2 5.9 2.7 7.8 5.9 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Kri1_C PF12936.7 RJW65621.1 - 4.3e-24 84.5 0.1 4.3e-24 84.5 0.1 3.3 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 RJW65621.1 - 3.8e-19 69.1 2.7 3.8e-19 69.1 2.7 3.1 2 1 0 2 2 2 1 KRI1-like family Nexin_C PF08628.12 RJW65621.1 - 0.26 11.9 0.2 0.26 11.9 0.2 2.7 3 0 0 3 3 3 0 Sorting nexin C terminal SSF PF00474.17 RJW65624.1 - 5.2e-45 154.0 19.4 6.6e-45 153.7 19.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 RJW65626.1 - 5.7e-05 22.2 1.1 6.7e-05 21.9 1.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family SPRY PF00622.28 RJW65627.1 - 2.5e-19 69.5 0.1 5.8e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 SPRY domain Proteasome PF00227.26 RJW65628.1 - 3.3e-44 150.6 1.5 5.7e-44 149.9 1.5 1.3 1 0 0 1 1 1 1 Proteasome subunit Metallophos PF00149.28 RJW65628.1 - 3.2e-10 40.9 0.2 9.7e-10 39.3 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4450 PF14614.6 RJW65629.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) RVT_1 PF00078.27 RJW65631.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Arrestin_C PF02752.22 RJW65634.1 - 5.2e-13 49.6 1.2 6.6e-11 42.8 1.7 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RJW65634.1 - 1.3e-12 48.0 0.0 8.6e-06 25.9 0.0 3.4 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Frag1 PF10277.9 RJW65639.1 - 3e-21 76.0 19.6 4.2e-21 75.5 19.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family FAD_binding_1 PF00667.20 RJW65640.1 - 2e-64 217.2 0.0 2.9e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 RJW65640.1 - 8e-18 65.1 0.0 1.9e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 RJW65640.1 - 4.2e-17 62.7 0.0 7.5e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_6 PF08030.12 RJW65640.1 - 0.009 16.2 0.0 0.034 14.2 0.0 1.9 1 1 1 2 2 2 1 Ferric reductase NAD binding domain PID PF00640.23 RJW65641.1 - 0.00011 22.2 5.3 0.00013 22.0 3.5 2.1 1 1 1 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) Pkinase PF00069.25 RJW65642.1 - 2.9e-28 99.0 0.0 4.7e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW65642.1 - 2.7e-20 72.7 0.0 4.2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1908 PF08926.11 RJW65642.1 - 0.99 8.4 9.5 0.16 11.0 4.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) 7tm_1 PF00001.21 RJW65643.1 - 1.1e-18 67.5 12.2 1.8e-18 66.8 12.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EVI2A PF05399.11 RJW65643.1 - 0.11 12.0 2.1 0.14 11.7 0.2 2.0 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) DUF5422 PF17459.2 RJW65643.1 - 1.2 9.3 8.4 5.8 7.1 2.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5422) Peptidase_M22 PF00814.25 RJW65644.1 - 9e-70 235.5 0.0 1e-69 235.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family EGF_CA PF07645.15 RJW65645.1 - 1.1e-07 32.0 3.8 1.1e-07 32.0 3.8 1.9 1 1 0 1 1 1 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 RJW65645.1 - 0.13 12.5 3.3 0.34 11.2 2.9 2.0 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Gpi16 PF04113.14 RJW65646.1 - 6.3e-91 305.5 0.0 2e-89 300.6 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component RVT_1 PF00078.27 RJW65647.1 - 1.1e-07 31.6 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IMPDH PF00478.25 RJW65648.1 - 1.8e-97 326.5 6.9 2.1e-97 326.3 6.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 RJW65648.1 - 4e-08 32.7 2.8 6.5e-08 32.0 1.7 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 RJW65648.1 - 4.7e-07 29.5 0.9 9.4e-07 28.5 0.9 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 RJW65648.1 - 6.5e-07 29.0 1.6 0.00058 19.4 0.2 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.14 RJW65648.1 - 0.0018 17.6 0.7 0.0036 16.7 0.7 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG CBS PF00571.28 RJW65648.1 - 0.0022 18.4 0.0 0.0046 17.4 0.0 1.6 1 0 0 1 1 1 1 CBS domain NanE PF04131.14 RJW65648.1 - 0.027 13.7 2.2 0.11 11.7 1.8 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Pkinase_Tyr PF07714.17 RJW65651.1 - 7e-66 222.1 0.0 1.3e-63 214.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW65651.1 - 1.8e-34 119.3 0.0 4e-33 114.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Cytochrom_B561 PF03188.16 RJW65654.1 - 2.4e-32 111.9 3.6 2.4e-32 111.9 3.6 1.8 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 RJW65654.1 - 1.3e-05 24.9 0.9 1.3e-05 24.9 0.9 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF2427) Ni_hydr_CYTB PF01292.20 RJW65654.1 - 4.8e-05 23.0 12.2 0.00015 21.4 6.7 2.1 1 1 1 2 2 2 2 Prokaryotic cytochrome b561 Frag1 PF10277.9 RJW65654.1 - 0.006 16.1 5.8 0.021 14.3 1.1 2.3 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Ferric_reduct PF01794.19 RJW65654.1 - 0.0084 16.2 12.3 0.045 13.9 6.0 2.5 2 1 0 2 2 2 2 Ferric reductase like transmembrane component DUF4079 PF13301.6 RJW65654.1 - 0.12 12.5 5.4 0.65 10.1 5.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF3357 PF11837.8 RJW65654.1 - 0.2 12.1 0.7 0.89 10.0 0.0 2.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) DHHC PF01529.20 RJW65654.1 - 0.48 10.5 6.3 9.9 6.3 0.1 2.9 3 0 0 3 3 3 0 DHHC palmitoyltransferase DctQ PF04290.12 RJW65654.1 - 7.1 6.5 13.3 0.19 11.6 3.5 2.7 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Gpi16 PF04113.14 RJW65655.1 - 0.0035 15.9 0.0 0.0043 15.6 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Trypsin PF00089.26 RJW65657.1 - 1.4e-62 211.4 0.5 2.1e-62 210.8 0.5 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 RJW65657.1 - 3.6e-11 43.4 0.1 4.3e-10 39.9 0.1 2.1 1 1 0 1 1 1 1 CUB domain Trypsin_2 PF13365.6 RJW65657.1 - 1.2e-07 32.8 0.0 2.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ldl_recept_a PF00057.18 RJW65657.1 - 2.1e-05 24.6 6.5 6.4e-05 23.1 6.5 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 RJW65657.1 - 0.024 15.0 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) PID PF00640.23 RJW65658.1 - 0.00037 20.5 0.3 0.0007 19.6 0.3 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) LIM PF00412.22 RJW65659.1 - 6.2e-43 144.8 47.0 4.6e-14 52.4 2.4 4.1 4 0 0 4 4 4 4 LIM domain zf-C4pol PF14260.6 RJW65659.1 - 0.0004 20.8 25.5 0.39 11.2 0.6 5.4 3 2 1 4 4 4 2 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 RJW65659.1 - 0.42 10.7 39.0 4.7 7.3 4.6 5.3 1 1 2 3 3 3 0 Double zinc ribbon DHHC PF01529.20 RJW65660.1 - 4e-18 65.8 15.2 4e-18 65.8 15.2 3.4 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_4 PF13637.6 RJW65660.1 - 5.2e-11 42.9 3.3 0.00048 20.6 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW65660.1 - 2.3e-09 37.7 0.7 2.2e-06 28.2 0.3 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW65660.1 - 1.8e-08 34.5 4.0 0.0018 18.5 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 RJW65660.1 - 5.2e-08 33.0 1.1 0.43 11.1 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RJW65660.1 - 4.7e-07 29.6 5.1 0.18 12.5 0.1 5.4 5 0 0 5 5 5 2 Ankyrin repeat zf-HC5HC2H PF13771.6 RJW65661.1 - 3.6e-12 46.4 2.5 3.6e-12 46.4 2.5 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RJW65661.1 - 0.00051 20.2 5.3 0.00051 20.2 5.3 2.2 2 1 0 2 2 2 1 PHD-zinc-finger like domain WRW PF10206.9 RJW65662.1 - 5.6e-35 119.8 0.2 1e-34 119.0 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f DUF2004 PF09406.10 RJW65662.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) LUC7 PF03194.15 RJW65664.1 - 9.7e-86 287.5 4.2 1.4e-85 287.0 4.2 1.2 1 0 0 1 1 1 1 LUC7 N_terminus kleA_kleC PF17383.2 RJW65664.1 - 0.045 14.1 3.6 0.06 13.7 0.3 2.8 2 2 2 4 4 4 0 Uncharacterized KorC regulated protein A Adeno_E4 PF05385.11 RJW65665.1 - 0.11 12.6 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein BCDHK_Adom3 PF10436.9 RJW65666.1 - 5.7e-43 146.5 0.5 7.6e-43 146.2 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RJW65666.1 - 3.2e-12 46.9 0.0 5.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NodS PF05401.11 RJW65666.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) HATPase_c_3 PF13589.6 RJW65666.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EGF_CA PF07645.15 RJW65669.1 - 2.8e-76 251.5 156.4 1.4e-11 44.4 10.1 14.1 13 1 0 13 13 13 10 Calcium-binding EGF domain cEGF PF12662.7 RJW65669.1 - 1.9e-43 146.0 81.4 4.3e-07 29.7 1.5 12.9 12 1 0 12 12 12 11 Complement Clr-like EGF-like EGF_3 PF12947.7 RJW65669.1 - 2.2e-11 43.8 101.4 0.0016 18.6 6.7 12.5 10 2 0 10 10 10 6 EGF domain EGF PF00008.27 RJW65669.1 - 5.7e-08 32.9 107.3 0.0086 16.4 0.8 12.9 12 2 0 12 12 12 7 EGF-like domain FXa_inhibition PF14670.6 RJW65669.1 - 0.00065 19.9 144.9 0.004 17.4 3.4 14.1 12 2 1 13 13 13 6 Coagulation Factor Xa inhibitory site hEGF PF12661.7 RJW65669.1 - 0.0008 20.0 10.0 0.0023 18.5 2.6 15.5 15 1 0 15 15 15 5 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 RJW65669.1 - 0.0037 17.3 5.0 0.0037 17.3 5.0 10.1 11 0 0 11 11 11 5 MSP1 EGF domain 1 PsbJ PF01788.17 RJW65670.1 - 1.3e-07 31.3 1.4 2.2e-07 30.6 1.4 1.3 1 0 0 1 1 1 1 PsbJ zf-HIT PF04438.16 RJW65671.1 - 2e-09 37.1 10.6 5.9e-09 35.7 10.6 1.9 1 0 0 1 1 1 1 HIT zinc finger SprT-like PF10263.9 RJW65672.1 - 7.5e-28 96.7 0.0 1.4e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 SprT-like family RNF220 PF15926.5 RJW65672.1 - 0.049 13.2 1.9 0.053 13.1 0.3 1.8 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Peptidase_M78 PF06114.13 RJW65672.1 - 0.097 12.6 0.8 0.19 11.7 0.8 1.3 1 0 0 1 1 1 0 IrrE N-terminal-like domain zf-CpG_bind_C PF12269.8 RJW65672.1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain RNA_pol_Rpb2_6 PF00562.28 RJW65673.1 - 3.3e-31 108.7 0.1 8.1e-31 107.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 RJW65673.1 - 8.4e-22 77.4 0.0 1.9e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RVT_1 PF00078.27 RJW65673.1 - 0.00052 19.6 0.2 0.0038 16.8 0.0 2.4 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF445 PF04286.12 RJW65673.1 - 0.0013 18.6 1.7 0.0018 18.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF445) Band_7_C PF16200.5 RJW65673.1 - 0.0013 18.7 0.1 3.8 7.6 0.0 3.0 2 2 0 2 2 2 2 C-terminal region of band_7 DNase-RNase PF02577.14 RJW65673.1 - 0.0042 16.7 0.3 3.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Bifunctional nuclease SYF2 PF08231.12 RJW65673.1 - 0.29 11.5 7.7 3.9 7.8 0.6 2.4 2 0 0 2 2 2 0 SYF2 splicing factor ArnB_C PF18677.1 RJW65673.1 - 0.84 9.8 3.8 34 4.6 0.0 3.3 2 1 1 3 3 3 0 Archaellum regulatory network B, C-terminal domain C1_2 PF03107.16 RJW65673.1 - 1 9.7 5.3 0.31 11.4 1.1 2.1 2 0 0 2 2 2 0 C1 domain Glutaredoxin PF00462.24 RJW65674.1 - 3.4e-21 75.2 0.0 1.2e-17 63.8 0.0 2.4 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 RJW65674.1 - 3.2e-14 52.8 0.0 6.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RJW65674.1 - 0.0011 19.4 0.0 0.0043 17.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain DIM1 PF02966.16 RJW65674.1 - 0.0013 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 AhpC-TSA PF00578.21 RJW65674.1 - 0.005 16.7 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RJW65674.1 - 0.0073 16.6 0.2 0.35 11.2 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like SH3BGR PF04908.15 RJW65674.1 - 0.04 14.1 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_3 PF13192.6 RJW65674.1 - 0.075 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin domain OST3_OST6 PF04756.13 RJW65674.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TraF PF13728.6 RJW65674.1 - 0.19 11.5 0.0 0.69 9.7 0.0 1.7 2 0 0 2 2 2 0 F plasmid transfer operon protein FEZ PF07763.13 RJW65675.1 - 4.8e-32 111.6 0.2 8.4e-32 110.8 0.2 1.4 1 0 0 1 1 1 1 FEZ-like protein SCHIP-1 PF10148.9 RJW65675.1 - 0.0069 16.0 0.2 0.015 15.0 0.2 1.5 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 DUF5102 PF17104.5 RJW65675.1 - 0.039 14.0 0.3 8.5 6.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5102) Sox_N PF12444.8 RJW65675.1 - 0.062 14.4 1.2 0.23 12.6 1.2 2.0 1 0 0 1 1 1 0 Sox developmental protein N terminal DUF2379 PF09543.10 RJW65675.1 - 0.61 10.3 2.6 3.3 7.9 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) E1_DerP2_DerF2 PF02221.15 RJW65676.1 - 1e-18 68.1 0.1 1.1e-18 67.9 0.1 1.0 1 0 0 1 1 1 1 ML domain DUF4407 PF14362.6 RJW65679.1 - 0.41 10.0 3.1 0.75 9.1 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) L27_1 PF09058.10 RJW65680.1 - 5.6e-23 80.7 1.9 5.6e-23 80.7 1.9 1.7 2 0 0 2 2 2 1 L27_1 PDZ PF00595.24 RJW65680.1 - 9.3e-18 64.4 0.1 1.6e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW65680.1 - 2.2e-11 43.4 0.3 3.4e-11 42.8 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW65680.1 - 0.029 14.7 0.1 0.061 13.7 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Abhydrolase_3 PF07859.13 RJW65682.1 - 1.4e-11 44.7 0.4 1.9e-11 44.2 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 RJW65682.1 - 6.5e-05 22.6 0.0 9.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 RJW65682.1 - 0.0014 19.2 0.4 0.0026 18.4 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 RJW65682.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) HIGH_NTase1 PF05636.11 RJW65683.1 - 0.074 12.2 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Ephrin_rec_like PF07699.13 RJW65686.1 - 7.7e-07 28.8 10.6 1.7e-05 24.5 10.9 2.6 1 1 1 2 2 2 1 Putative ephrin-receptor like NCD3G PF07562.14 RJW65686.1 - 0.43 10.6 7.3 0.14 12.2 2.3 2.5 2 1 0 3 3 3 0 Nine Cysteines Domain of family 3 GPCR Cytochrom_B561 PF03188.16 RJW65687.1 - 3.5e-32 111.4 6.9 3.5e-32 111.4 6.9 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 RJW65687.1 - 3e-05 23.7 5.6 3e-05 23.7 5.6 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF2427) Trypan_PARP PF05887.11 RJW65687.1 - 0.099 12.6 0.1 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4079 PF13301.6 RJW65687.1 - 2 8.6 14.0 0.77 9.9 3.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 RJW65687.1 - 2.2 7.8 20.5 4.9 6.7 19.3 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 FG-GAP PF01839.23 RJW65688.1 - 1.7e-14 53.6 7.4 2.2e-09 37.3 2.3 3.7 3 0 0 3 3 3 2 FG-GAP repeat Integrin_alpha2 PF08441.12 RJW65688.1 - 2.5e-08 33.3 0.0 5.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Integrin alpha VCBS PF13517.6 RJW65688.1 - 2.1e-07 31.4 0.2 7.9e-07 29.6 0.2 2.1 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PsbJ PF01788.17 RJW65688.1 - 5e-07 29.5 1.4 1.3e-06 28.2 1.4 1.6 1 0 0 1 1 1 1 PsbJ FG-GAP_2 PF14312.6 RJW65688.1 - 2.4e-05 24.5 3.8 2.8 8.2 0.0 3.7 3 0 0 3 3 3 3 FG-GAP repeat PIG-L PF02585.17 RJW65689.1 - 8.5e-26 91.1 0.0 1.1e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SPOC PF07744.13 RJW65690.1 - 1.8e-35 122.1 0.1 3.6e-35 121.1 0.1 1.6 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 RJW65690.1 - 2.7e-22 78.4 0.3 2.3e-11 43.3 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RJW65690.1 - 0.034 14.2 1.1 9.5 6.4 0.0 3.7 4 0 0 4 4 4 0 Limkain b1 Septin PF00735.18 RJW65691.1 - 3.2e-104 348.2 0.0 5.8e-104 347.3 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 RJW65691.1 - 3.8e-08 33.4 0.0 1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RJW65691.1 - 0.0003 20.2 0.0 0.00088 18.7 0.0 1.8 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 RJW65691.1 - 0.0012 18.8 4.3 0.0022 17.9 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 RJW65691.1 - 0.0075 15.7 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 RJW65691.1 - 0.012 15.9 0.0 0.095 13.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 RJW65691.1 - 0.014 14.9 0.6 9.3 5.7 0.4 3.1 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 RJW65691.1 - 0.023 15.1 0.2 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF1719 PF08224.11 RJW65691.1 - 0.031 13.4 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Spore_GerAC PF05504.11 RJW65691.1 - 0.032 14.4 5.1 0.069 13.4 5.1 1.5 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Pox_A32 PF04665.12 RJW65691.1 - 0.032 13.7 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein IIGP PF05049.13 RJW65691.1 - 0.048 12.7 2.0 0.061 12.4 0.1 2.1 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 RJW65691.1 - 0.053 13.1 0.5 0.12 11.9 0.0 1.9 2 0 0 2 2 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 RJW65691.1 - 0.06 13.9 1.6 0.87 10.1 0.0 2.6 3 0 0 3 3 2 0 ABC transporter Ras PF00071.22 RJW65691.1 - 0.065 12.8 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 RJW65691.1 - 0.14 12.0 0.0 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 RJW65691.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 RJW65691.1 - 0.17 11.9 8.1 0.73 9.9 0.3 3.3 2 1 1 3 3 3 0 Dynamin family Fez1 PF06818.15 RJW65691.1 - 0.32 11.4 13.8 0.6 10.5 13.8 1.4 1 0 0 1 1 1 0 Fez1 AAA_24 PF13479.6 RJW65691.1 - 0.68 9.6 3.2 0.78 9.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain Coiled-coil_56 PF09813.9 RJW65691.1 - 3.2 7.9 6.1 11 6.1 4.8 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Sugar_tr PF00083.24 RJW65694.1 - 1.5e-27 96.6 10.9 2.3e-27 96.0 10.9 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW65694.1 - 6.8e-17 61.4 21.7 1.3e-15 57.2 19.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily YabA PF06156.13 RJW65695.1 - 0.29 11.8 2.4 0.44 11.2 0.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 RJW65695.1 - 4.2 7.6 6.4 11 6.2 0.7 2.4 2 0 0 2 2 2 0 bZIP transcription factor Aldolase_II PF00596.21 RJW65696.1 - 1.2e-40 139.5 0.2 1.8e-40 138.9 0.2 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SIKE PF05769.11 RJW65699.1 - 1e-22 80.9 0.5 1.2e-22 80.7 0.5 1.0 1 0 0 1 1 1 1 SIKE family DUF150 PF02576.17 RJW65699.1 - 0.083 13.3 0.1 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 RimP N-terminal domain PikAIV_N PF18605.1 RJW65699.1 - 0.086 12.4 3.7 4.9 6.8 1.1 2.3 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF5341 PF17276.2 RJW65699.1 - 0.15 12.2 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5341) Exonuc_VII_S PF02609.16 RJW65699.1 - 1.2 9.2 6.5 2 8.5 0.2 2.6 3 0 0 3 3 3 0 Exonuclease VII small subunit 7tm_1 PF00001.21 RJW65701.1 - 1.5e-05 24.4 17.0 2e-05 24.1 17.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 RJW65701.1 - 0.0085 15.6 9.0 0.0085 15.6 9.0 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srx PF10328.9 RJW65701.1 - 0.03 13.9 18.6 0.067 12.8 18.7 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx RHD3 PF05879.12 RJW65701.1 - 0.83 7.7 2.1 1.2 7.2 2.1 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Laps PF10169.9 RJW65705.1 - 2.7e-10 40.9 9.0 5.9e-10 39.8 9.0 1.5 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 RJW65705.1 - 0.0018 18.4 3.0 0.0053 17.0 3.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) SRF-TF PF00319.18 RJW65705.1 - 0.07 12.6 2.3 0.22 11.1 0.7 2.3 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) CPSF100_C PF13299.6 RJW65706.1 - 5.7e-33 114.5 0.0 1.2e-32 113.5 0.0 1.5 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_6 PF16661.5 RJW65706.1 - 6.9e-21 74.6 0.0 1.5e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 RJW65706.1 - 3.8e-11 43.3 0.0 9.1e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 RJW65706.1 - 0.0045 16.9 0.0 0.0096 15.8 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Syntaxin PF00804.25 RJW65707.1 - 8.2e-57 192.1 21.2 8.2e-57 192.1 21.2 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 RJW65707.1 - 4.1e-12 45.9 0.7 4.1e-12 45.9 0.7 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 RJW65707.1 - 4.1e-06 27.1 5.3 4.1e-06 27.1 5.3 2.8 2 1 0 2 2 2 1 Syntaxin-like protein RVT_1 PF00078.27 RJW65707.1 - 0.00018 21.1 0.0 0.00042 19.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_13 PF13166.6 RJW65707.1 - 0.029 13.1 18.0 0.04 12.6 18.0 1.1 1 0 0 1 1 1 0 AAA domain Lzipper-MIP1 PF14389.6 RJW65707.1 - 0.049 13.9 0.9 0.049 13.9 0.9 2.6 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 MCPsignal PF00015.21 RJW65707.1 - 0.11 12.3 9.4 0.97 9.2 1.2 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IMS PF00817.20 RJW65707.1 - 1.5 8.8 6.0 12 5.9 6.0 2.2 1 1 0 1 1 1 0 impB/mucB/samB family Fez1 PF06818.15 RJW65707.1 - 2.1 8.7 15.7 1.9 8.9 0.7 2.2 2 0 0 2 2 2 0 Fez1 Mod_r PF07200.13 RJW65707.1 - 3.9 7.6 15.6 0.8 9.8 3.5 2.6 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein V-SNARE PF05008.15 RJW65707.1 - 4.3 7.8 15.3 3.7 8.0 3.9 3.3 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2203 PF09969.9 RJW65707.1 - 6.8 7.4 14.2 7 7.4 2.9 2.7 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Sugar_tr PF00083.24 RJW65708.1 - 5.9e-27 94.6 14.1 9e-27 94.0 14.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW65708.1 - 1.6e-18 66.8 28.6 4.7e-18 65.2 17.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily P5-ATPase PF12409.8 RJW65708.1 - 2.5 8.2 5.4 0.64 10.1 0.4 2.3 2 1 0 2 2 2 0 P5-type ATPase cation transporter Proteasom_PSMB PF10508.9 RJW65709.1 - 2e-25 89.3 0.0 1.2e-24 86.7 0.0 1.8 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 RJW65709.1 - 0.015 15.6 0.1 7.3 7.1 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats GIY-YIG PF01541.24 RJW65710.1 - 0.048 13.9 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain E1_DerP2_DerF2 PF02221.15 RJW65711.1 - 7.9e-20 71.7 0.1 1.1e-19 71.2 0.1 1.2 1 0 0 1 1 1 1 ML domain Lipocalin_3 PF12702.7 RJW65711.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipocalin-like Peptidase_C12 PF01088.21 RJW65712.1 - 3.4e-56 190.3 0.0 2.6e-38 131.9 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 RJW65712.1 - 6.3e-13 48.4 0.1 1.2e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases AAA PF00004.29 RJW65713.1 - 7.2e-54 181.8 0.0 4.2e-41 140.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RJW65713.1 - 4e-07 29.9 0.0 0.0028 17.4 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RJW65713.1 - 4.2e-07 30.5 0.8 0.0086 16.5 0.1 4.0 2 2 2 4 4 4 1 AAA ATPase domain Rad17 PF03215.15 RJW65713.1 - 7.4e-07 29.3 0.0 0.00032 20.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_lid_3 PF17862.1 RJW65713.1 - 1.1e-06 28.4 0.1 0.00011 22.0 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 RJW65713.1 - 8.3e-06 25.8 0.4 0.0019 18.2 0.0 3.3 3 2 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RJW65713.1 - 8.1e-05 22.9 0.2 0.032 14.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RJW65713.1 - 9.6e-05 22.9 0.0 0.011 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 RJW65713.1 - 0.0001 22.3 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 RJW65713.1 - 0.00016 21.8 0.0 0.0032 17.6 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RJW65713.1 - 0.00034 20.8 0.0 0.042 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RJW65713.1 - 0.00063 20.1 0.0 0.15 12.4 0.0 2.8 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 RJW65713.1 - 0.0011 18.4 1.6 0.052 12.9 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RJW65713.1 - 0.0019 18.2 1.0 0.18 11.7 0.1 3.2 3 1 0 3 3 2 1 NACHT domain AAA_28 PF13521.6 RJW65713.1 - 0.0035 17.6 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 RJW65713.1 - 0.0048 16.7 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RJW65713.1 - 0.0066 16.5 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 RJW65713.1 - 0.01 15.9 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 RJW65713.1 - 0.012 15.3 0.0 0.087 12.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.13 RJW65713.1 - 0.015 14.5 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_11 PF13086.6 RJW65713.1 - 0.019 14.7 0.0 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 RJW65713.1 - 0.022 14.3 0.7 9.7 5.7 0.1 3.2 2 1 1 3 3 3 0 AAA domain SRPRB PF09439.10 RJW65713.1 - 0.064 12.7 0.0 15 5.0 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 RJW65713.1 - 0.074 12.7 0.0 0.6 9.8 0.0 2.4 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 RJW65713.1 - 0.083 13.3 0.2 0.52 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RJW65713.1 - 0.11 13.1 0.0 9.1 6.8 0.0 3.1 3 0 0 3 3 3 0 ABC transporter AAA_7 PF12775.7 RJW65713.1 - 0.18 11.3 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 RJW65713.1 - 0.21 11.9 0.5 6.1 7.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain DNA_pol_phi PF04931.13 RJW65714.1 - 6.5e-34 117.1 8.7 4.5e-33 114.4 8.7 2.2 1 1 0 1 1 1 1 DNA polymerase phi Goodbye PF17109.5 RJW65714.1 - 0.59 10.6 2.4 61 4.1 1.0 3.5 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain VHL PF01847.16 RJW65715.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 VHL beta domain Reticulon PF02453.17 RJW65717.1 - 3.2e-39 134.4 3.6 7.4e-39 133.2 2.4 1.8 1 1 1 2 2 2 1 Reticulon PRT_C PF08372.10 RJW65717.1 - 0.012 15.4 0.5 0.053 13.3 0.5 1.9 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF842 PF05811.13 RJW65717.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Clat_adaptor_s PF01217.20 RJW65718.1 - 1.9e-15 57.1 0.2 2.6e-15 56.6 0.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Gasdermin_C PF17708.1 RJW65718.1 - 0.00077 19.6 0.1 0.0011 19.1 0.1 1.2 1 0 0 1 1 1 1 Gasdermin PUB domain Proho_convert PF12177.8 RJW65720.1 - 0.093 12.7 0.7 0.093 12.7 0.7 2.0 2 0 0 2 2 2 0 Prohormone convertase enzyme Methyltransf_16 PF10294.9 RJW65721.1 - 1.1e-08 35.1 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 RJW65721.1 - 0.0079 16.0 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RWD PF05773.22 RJW65723.1 - 4.1e-08 33.5 0.0 7.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain M60-like_N PF17291.2 RJW65724.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases Baculo_PEP_C PF04513.12 RJW65725.1 - 0.29 11.2 1.4 0.71 9.9 1.4 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus polyprenyl_synt PF00348.17 RJW65726.1 - 1.1e-63 214.7 0.0 1.4e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CTP_transf_like PF01467.26 RJW65726.1 - 0.066 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase-like G-patch PF01585.23 RJW65727.1 - 1.3e-12 47.4 1.1 2.9e-12 46.3 1.1 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 RJW65727.1 - 1.4e-06 28.1 0.1 2.6e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 RJW65727.1 - 0.018 15.1 0.4 0.052 13.7 0.4 1.7 1 0 0 1 1 1 0 G-patch domain RRM_occluded PF16842.5 RJW65727.1 - 0.019 14.8 0.0 0.07 13.0 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif Lipase_bact_N PF12262.8 RJW65727.1 - 0.039 13.3 0.1 0.1 11.9 0.1 1.6 2 0 0 2 2 2 0 Bacterial virulence factor lipase N-terminal THOC7 PF05615.13 RJW65728.1 - 2.4e-26 92.5 3.0 2.4e-26 92.5 3.0 1.7 1 1 0 1 1 1 1 Tho complex subunit 7 FlgN PF05130.12 RJW65728.1 - 0.022 15.3 0.8 0.022 15.3 0.8 2.1 1 1 1 2 2 2 0 FlgN protein DUF2017 PF09438.10 RJW65728.1 - 0.12 12.3 0.3 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) DUF2524 PF10732.9 RJW65728.1 - 0.13 12.6 5.2 0.058 13.7 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) CotJB PF12652.7 RJW65728.1 - 0.24 11.7 2.0 14 6.0 0.4 2.3 2 0 0 2 2 2 0 CotJB protein Exonuc_VII_L PF02601.15 RJW65728.1 - 0.29 10.7 3.0 0.4 10.2 3.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4619 PF15398.6 RJW65728.1 - 3 7.3 6.8 4.5 6.7 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) CHDCT2 PF08074.11 RJW65729.1 - 4.3e-74 248.3 0.2 1.7e-73 246.4 0.2 2.1 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain SNF2_N PF00176.23 RJW65729.1 - 4.2e-57 193.5 0.0 1.5e-56 191.7 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain DUF1086 PF06461.11 RJW65729.1 - 1.2e-45 154.7 0.0 2.9e-45 153.5 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) DUF1087 PF06465.13 RJW65729.1 - 7.8e-26 89.9 4.5 7.8e-26 89.9 4.5 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) CHDNT PF08073.12 RJW65729.1 - 8.4e-20 70.5 0.9 5.8e-19 67.8 0.6 2.4 2 0 0 2 2 2 1 CHDNT (NUC034) domain Helicase_C PF00271.31 RJW65729.1 - 1.1e-19 70.8 0.0 2.7e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 RJW65729.1 - 1.7e-18 66.2 26.0 2.7e-10 40.0 7.8 2.5 2 0 0 2 2 2 2 PHD-finger Chromo PF00385.24 RJW65729.1 - 1.6e-17 63.1 1.1 4.8e-13 48.8 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 RJW65729.1 - 8e-10 39.0 0.0 3.6e-09 36.9 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RJW65729.1 - 6.7e-06 25.5 0.0 2.1e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-HC5HC2H_2 PF13832.6 RJW65729.1 - 0.01 16.0 6.2 1.2 9.3 0.2 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain AAA_22 PF13401.6 RJW65729.1 - 0.021 15.1 2.0 0.098 12.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain PHD_2 PF13831.6 RJW65729.1 - 0.13 11.9 11.2 0.43 10.2 2.7 2.7 2 0 0 2 2 2 0 PHD-finger zf-ISL3 PF14690.6 RJW65729.1 - 0.21 12.3 3.0 0.97 10.2 0.6 2.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-PHD-like PF15446.6 RJW65729.1 - 1.2 8.7 10.4 6.4 6.4 0.9 3.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 RJW65729.1 - 1.3 8.9 14.1 1.9 8.4 1.2 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) E1_DerP2_DerF2 PF02221.15 RJW65730.1 - 2.9e-23 82.8 0.1 1.2e-22 80.8 0.0 1.7 1 1 1 2 2 2 1 ML domain LPD30 PF18850.1 RJW65730.1 - 0.054 13.2 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 7tm_1 PF00001.21 RJW65733.1 - 5e-08 32.6 20.9 5e-08 32.6 20.9 2.2 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Syndecan PF01034.20 RJW65733.1 - 0.84 9.6 5.0 6.2 6.8 0.1 2.8 2 0 0 2 2 2 0 Syndecan domain DRAT PF07357.11 RJW65736.1 - 0.037 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Pkinase_Tyr PF07714.17 RJW65739.1 - 1.2e-89 300.0 0.0 1.9e-89 299.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW65739.1 - 7.5e-44 150.1 0.0 1.2e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ephrin_lbd PF01404.19 RJW65739.1 - 4.2e-16 59.5 0.2 1e-15 58.2 0.1 1.8 2 0 0 2 2 2 1 Ephrin receptor ligand binding domain fn3 PF00041.21 RJW65739.1 - 0.00026 21.3 3.0 0.0079 16.5 0.0 3.8 3 1 1 4 4 4 1 Fibronectin type III domain Ephrin_rec_like PF07699.13 RJW65739.1 - 0.004 16.9 1.7 0.004 16.9 1.7 2.6 2 0 0 2 2 2 1 Putative ephrin-receptor like Pkinase_fungal PF17667.1 RJW65739.1 - 0.0042 15.9 0.0 0.0063 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW65739.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EGF_3 PF12947.7 RJW65739.1 - 0.12 12.5 1.5 1.6 9.0 0.1 2.7 2 0 0 2 2 2 0 EGF domain Haspin_kinase PF12330.8 RJW65739.1 - 0.12 11.2 0.3 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain hEGF PF12661.7 RJW65739.1 - 0.17 12.6 3.1 4 8.2 0.2 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF cEGF PF12662.7 RJW65739.1 - 0.2 11.6 8.3 3.5 7.7 1.3 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like CBFD_NFYB_HMF PF00808.23 RJW65740.1 - 1.6e-29 102.0 0.7 2.3e-29 101.5 0.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RJW65740.1 - 2.1e-05 24.9 0.1 4.1e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RJW65740.1 - 0.00093 19.3 0.0 0.0022 18.1 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 RJW65740.1 - 0.057 13.4 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.13 RJW65740.1 - 0.084 13.4 0.0 1.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Choline_kinase PF01633.20 RJW65741.1 - 5.4e-53 179.7 0.0 5.8e-52 176.4 0.0 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 RJW65741.1 - 2.2e-11 44.2 0.0 3.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 RJW65741.1 - 0.043 13.1 0.1 0.079 12.3 0.1 1.4 1 1 0 1 1 1 0 Ecdysteroid kinase Pkinase_Tyr PF07714.17 RJW65742.1 - 3e-11 43.1 0.0 7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW65742.1 - 1.1e-06 28.3 0.0 1.9e-05 24.1 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain zf-RING_2 PF13639.6 RJW65743.1 - 1.1e-11 44.9 42.3 2.5e-07 30.9 10.9 3.4 3 0 0 3 3 3 2 Ring finger domain PHD PF00628.29 RJW65743.1 - 5.4e-11 42.2 5.8 5.4e-11 42.2 5.8 3.5 3 1 1 4 4 3 1 PHD-finger Zn_ribbon_17 PF17120.5 RJW65743.1 - 1e-07 31.4 29.9 1.4e-05 24.6 7.1 3.3 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 RJW65743.1 - 1.6e-06 27.8 10.2 1.6e-06 27.8 10.2 3.8 3 1 1 4 4 3 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW65743.1 - 1.3e-05 25.4 32.0 0.0028 17.9 9.4 3.7 3 1 0 3 3 3 2 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RJW65743.1 - 1.3e-05 24.9 37.2 3.7e-05 23.5 10.5 3.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW65743.1 - 1.4e-05 24.8 6.7 1.4e-05 24.8 6.7 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW65743.1 - 7e-05 22.8 11.2 7e-05 22.8 11.2 3.5 4 0 0 4 4 3 2 RING-type zinc-finger zf-RING_10 PF16685.5 RJW65743.1 - 0.0014 18.7 5.5 0.0014 18.7 5.5 3.1 3 0 0 3 3 3 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 RJW65743.1 - 0.002 18.2 9.8 0.002 18.2 9.8 3.7 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.6 RJW65743.1 - 0.0025 18.0 20.3 0.0037 17.5 3.6 3.6 2 1 1 3 3 3 2 PHD-like zinc-binding domain zf-ANAPC11 PF12861.7 RJW65743.1 - 0.025 14.6 21.9 0.67 10.1 1.7 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 RJW65743.1 - 0.08 12.8 13.3 0.14 12.0 3.3 2.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Cactin_mid PF10312.9 RJW65743.1 - 0.12 12.1 4.6 0.28 10.9 4.6 1.5 1 0 0 1 1 1 0 Conserved mid region of cactin FANCL_C PF11793.8 RJW65743.1 - 0.28 11.4 24.0 0.43 10.8 3.8 3.6 3 0 0 3 3 3 0 FANCL C-terminal domain Zf_RING PF16744.5 RJW65743.1 - 0.94 9.6 23.3 0.13 12.4 2.5 3.3 3 0 0 3 3 2 0 KIAA1045 RING finger zf-HC5HC2H_2 PF13832.6 RJW65743.1 - 6.6 6.9 20.0 0.2 11.8 3.9 3.4 2 1 1 3 3 3 0 PHD-zinc-finger like domain MIP-T3_C PF17749.1 RJW65744.1 - 2.4e-36 125.0 8.2 2.4e-36 125.0 8.2 2.4 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 RJW65744.1 - 4.4e-18 65.3 0.0 1e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain RVT_1 PF00078.27 RJW65744.1 - 7.1e-10 38.8 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spc7 PF08317.11 RJW65744.1 - 0.0013 17.7 4.6 0.0023 16.9 4.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Fib_alpha PF08702.10 RJW65744.1 - 0.0062 16.7 3.2 0.059 13.6 2.8 2.6 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 RJW65744.1 - 4.9 7.6 9.5 2.4 8.6 6.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Laminin_N PF00055.17 RJW65745.1 - 0.082 12.5 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Laminin N-terminal (Domain VI) Ephrin_lbd PF01404.19 RJW65746.1 - 2.9e-11 43.8 0.0 1.1e-10 41.9 0.0 1.8 1 1 1 2 2 2 1 Ephrin receptor ligand binding domain DHHC PF01529.20 RJW65747.1 - 3.1e-29 101.8 13.3 4.4e-29 101.3 13.3 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Peptidase_M49 PF03571.15 RJW65749.1 - 6.2e-212 704.9 0.0 7.2e-212 704.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Radical_SAM PF04055.21 RJW65752.1 - 2.7e-31 109.2 0.0 1.1e-30 107.2 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily RVT_1 PF00078.27 RJW65752.1 - 9.5e-26 90.7 0.0 1.6e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRAM PF01938.20 RJW65752.1 - 3.7e-11 42.8 0.0 7.8e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 TRAM domain UPF0004 PF00919.20 RJW65752.1 - 1.9e-08 34.3 0.0 5.3e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 C2 PF00168.30 RJW65754.1 - 2e-36 124.4 0.2 5.8e-17 61.9 0.1 2.4 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 RJW65754.1 - 4.2e-16 59.2 4.6 7.9e-16 58.3 4.6 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger PilJ_C PF18223.1 RJW65754.1 - 0.062 13.8 1.2 0.15 12.6 0.4 2.0 2 0 0 2 2 2 0 Pili PilJ C-terminal domain zf-C3HC4 PF00097.25 RJW65754.1 - 0.13 12.1 10.0 0.37 10.7 10.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 RJW65754.1 - 0.23 11.6 4.0 0.51 10.5 4.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-CRD PF17979.1 RJW65754.1 - 0.24 11.5 4.9 0.6 10.2 4.9 1.6 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions IBR PF01485.21 RJW65754.1 - 0.85 9.9 7.3 0.85 9.9 5.9 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 RJW65754.1 - 1 9.2 10.5 3 7.8 10.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW65754.1 - 1.2 9.5 10.8 2.8 8.4 10.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_10 PF16685.5 RJW65754.1 - 4.6 7.5 7.2 9.5 6.4 7.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 RJW65754.1 - 7.6 6.6 9.7 59 3.7 9.7 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RJW65754.1 - 8.8 6.3 9.6 2.1 8.3 2.4 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_pol_Rpb2_1 PF04563.15 RJW65755.1 - 2.3e-48 164.4 0.0 3.6e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_6 PF00562.28 RJW65755.1 - 6.3e-35 121.0 0.1 9.9e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RVT_1 PF00078.27 RJW65755.1 - 5.3e-33 114.4 0.0 9.5e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpb2_4 PF04566.13 RJW65755.1 - 1.8e-22 79.4 0.9 3.7e-22 78.4 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 RJW65755.1 - 1.3e-21 76.6 0.1 2.8e-21 75.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 RJW65755.1 - 1.1e-12 48.3 0.1 2.5e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_2 PF04561.14 RJW65755.1 - 4.9e-11 42.6 0.7 4.2e-09 36.3 0.0 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 2 Peptidase_M24 PF00557.24 RJW65756.1 - 8.4e-32 110.5 0.0 1.1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CD36 PF01130.21 RJW65756.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 CD36 family Sgf11 PF08209.11 RJW65758.1 - 6.1e-09 35.3 7.2 1.2e-08 34.4 7.2 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) RBM39linker PF15519.6 RJW65759.1 - 0.024 15.7 1.3 0.096 13.8 0.0 2.7 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein E1_DerP2_DerF2 PF02221.15 RJW65759.1 - 0.099 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 ML domain EF-hand_4 PF12763.7 RJW65761.1 - 5.4e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 RJW65761.1 - 0.00021 20.6 0.0 0.00053 19.3 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 RJW65761.1 - 0.012 16.1 0.2 0.051 14.0 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 RJW65761.1 - 0.023 14.6 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 RJW65761.1 - 0.073 13.0 0.2 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain DUF3867 PF12983.7 RJW65761.1 - 0.14 12.2 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) HSNSD PF12062.8 RJW65762.1 - 1.9e-89 300.7 0.0 1.4e-71 241.7 0.2 2.6 2 1 0 2 2 2 2 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 RJW65762.1 - 1.7e-18 67.0 0.0 3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW65762.1 - 8.6e-10 39.4 1.5 0.008 16.6 0.2 3.6 1 1 2 3 3 3 3 Sulfotransferase family Complex1_LYR PF05347.15 RJW65763.1 - 0.0009 19.2 4.2 0.0041 17.1 4.2 1.9 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RJW65763.1 - 0.087 13.6 0.2 0.12 13.1 0.2 1.2 1 0 0 1 1 1 0 Complex1_LYR-like PX PF00787.24 RJW65764.1 - 1.7e-07 31.2 0.3 1.7e-06 28.0 0.3 2.2 1 1 0 1 1 1 1 PX domain LMBR1 PF04791.16 RJW65764.1 - 0.17 10.8 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ank_2 PF12796.7 RJW65765.1 - 4e-18 65.8 8.8 4.6e-10 39.9 1.5 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW65765.1 - 1.4e-16 60.3 3.6 3.9e-09 36.6 0.3 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW65765.1 - 4.3e-13 49.5 3.0 2.1e-05 25.0 0.4 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW65765.1 - 9.9e-13 47.1 2.0 0.054 14.1 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RJW65765.1 - 2.2e-09 37.3 4.4 0.094 13.2 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Castor1_N PF18700.1 RJW65765.1 - 0.044 13.6 0.0 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain CCD48 PF15799.5 RJW65765.1 - 0.066 11.5 0.1 0.11 10.8 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Nucleoporin_FG2 PF15967.5 RJW65766.1 - 0.18 10.3 31.1 0.0052 15.4 6.1 2.4 1 1 0 2 2 2 0 Nucleoporin FG repeated region zf-C2H2_2 PF12756.7 RJW65768.1 - 4.8e-05 23.6 11.3 0.05 13.9 1.3 3.5 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 RJW65768.1 - 0.00032 21.0 15.1 0.044 14.3 0.5 4.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2HE PF16278.5 RJW65768.1 - 0.086 13.3 2.1 0.31 11.5 0.2 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 RJW65768.1 - 0.25 12.3 13.2 0.72 10.8 0.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-FCS PF06467.14 RJW65768.1 - 2.7 8.0 5.0 8.2 6.5 1.6 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HLH PF00010.26 RJW65769.1 - 8.9e-13 48.0 0.0 2.2e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RNA_pol_Rpb2_6 PF00562.28 RJW65770.1 - 1.2e-77 261.7 0.0 1.6e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 RJW65770.1 - 1.3e-29 102.4 0.2 2.3e-29 101.6 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Pkinase PF00069.25 RJW65771.1 - 1.5e-12 47.5 0.0 3.3e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain LRR_6 PF13516.6 RJW65772.1 - 3.5e-23 79.6 12.4 0.0034 17.3 0.0 9.3 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 RJW65772.1 - 4.2e-08 33.4 3.9 0.02 15.3 0.0 6.0 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW65772.1 - 0.0019 18.5 3.2 14 6.7 0.0 6.9 10 1 0 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.6 RJW65772.1 - 0.11 12.3 11.0 2.5 7.9 0.1 5.6 4 2 1 5 5 5 0 Leucine rich repeat Ribosomal_L18A PF01775.17 RJW65773.1 - 5e-55 184.8 0.3 6.1e-55 184.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A zf-RanBP PF00641.18 RJW65775.1 - 3.9e-20 70.9 43.7 3.2e-07 29.5 2.8 4.5 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Nup153 PF08604.10 RJW65775.1 - 1.1e-09 37.7 0.6 1.1e-09 37.7 0.6 4.5 3 1 2 5 5 5 1 Nucleoporin Nup153-like zf-Sec23_Sec24 PF04810.15 RJW65775.1 - 2.4 8.3 17.0 24 5.1 0.0 4.9 4 1 1 5 5 5 0 Sec23/Sec24 zinc finger RRM_1 PF00076.22 RJW65777.1 - 6.2e-38 128.5 0.1 3.4e-18 65.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RJW65777.1 - 0.0015 18.5 0.0 0.65 10.1 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 RJW65777.1 - 0.076 13.1 0.0 23 5.2 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif NOP5NT PF08156.13 RJW65777.1 - 1.8 9.0 6.6 4.8 7.6 0.0 3.3 4 0 0 4 4 4 0 NOP5NT (NUC127) domain Asp PF00026.23 RJW65778.1 - 1.4e-26 93.7 0.0 1.6e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW65778.1 - 0.051 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Inositol_P PF00459.25 RJW65780.1 - 1.1e-28 100.5 0.0 1e-26 94.1 0.0 2.1 1 1 0 1 1 1 1 Inositol monophosphatase family NADH5_C PF06455.11 RJW65780.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus DUF4479 PF14794.6 RJW65781.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) His_kinase PF06580.13 RJW65781.1 - 0.28 11.5 0.1 0.28 11.5 0.1 1.8 2 0 0 2 2 2 0 Histidine kinase COesterase PF00135.28 RJW65782.1 - 3.8e-115 385.7 0.0 1.2e-114 384.0 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RJW65782.1 - 3e-05 24.0 1.2 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold MtrH PF02007.18 RJW65782.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit RVT_1 PF00078.27 RJW65783.1 - 3.8e-07 29.8 0.0 5.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ldl_recept_a PF00057.18 RJW65785.1 - 0.00018 21.7 7.9 0.00052 20.2 7.9 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Cullin PF00888.22 RJW65785.1 - 0.048 12.3 0.0 0.069 11.8 0.0 1.1 1 0 0 1 1 1 0 Cullin family SDA1 PF05285.12 RJW65786.1 - 0.38 10.1 71.4 0.49 9.8 71.4 1.2 1 0 0 1 1 1 0 SDA1 zf-C2H2 PF00096.26 RJW65788.1 - 8.5e-26 88.9 61.6 0.00051 20.3 0.2 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW65788.1 - 1.3e-25 87.9 64.0 0.0048 17.6 0.2 9.1 10 0 0 10 10 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW65788.1 - 1.2e-17 63.4 64.9 2.7e-05 24.4 1.2 10.3 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW65788.1 - 3.8e-07 29.9 49.9 0.051 13.6 0.1 8.5 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW65788.1 - 3.5e-06 26.7 42.7 0.13 12.0 1.3 7.8 8 0 0 8 8 8 5 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 RJW65788.1 - 2.2e-05 24.2 4.2 0.0003 20.6 0.1 8.4 8 1 0 8 8 8 3 zinc-finger of a C2HC-type zf-met PF12874.7 RJW65788.1 - 0.00017 21.9 40.3 0.63 10.5 0.1 8.3 8 0 0 8 8 8 4 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 RJW65788.1 - 0.0074 16.2 5.6 0.0074 16.2 5.6 5.3 6 1 1 7 7 6 2 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 RJW65788.1 - 0.024 14.4 36.4 0.053 13.3 2.4 7.4 7 0 0 7 7 7 0 C2H2-type zinc-finger domain Rad50_zn_hook PF04423.14 RJW65788.1 - 0.045 13.6 0.1 0.045 13.6 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_3rep PF18868.1 RJW65788.1 - 0.053 14.2 35.4 0.35 11.5 9.7 3.7 2 2 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Ta0938 PF11494.8 RJW65788.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.9 2 2 2 5 5 5 0 Ta0938 Ribosomal_S14 PF00253.21 RJW65788.1 - 0.38 10.5 9.5 5.4 6.9 0.0 4.5 4 0 0 4 4 4 0 Ribosomal protein S14p/S29e FYVE PF01363.21 RJW65788.1 - 0.59 10.3 50.0 9.7 6.4 0.3 6.7 3 2 2 5 5 5 0 FYVE zinc finger zf-C2H2_jaz PF12171.8 RJW65788.1 - 2 8.8 36.9 2.1 8.8 0.1 8.0 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding Serpin PF00079.20 RJW65790.1 - 9.7e-50 169.9 0.0 4.3e-43 148.0 0.0 2.0 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) ZFYVE21_C PF16696.5 RJW65791.1 - 0.033 14.0 0.3 0.28 11.1 0.0 2.1 1 1 1 2 2 2 0 Zinc finger FYVE domain-containing protein 21 C-terminus PC4 PF02229.16 RJW65792.1 - 2.6e-25 87.8 0.4 3e-25 87.6 0.4 1.1 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) zf-H2C2_2 PF13465.6 RJW65793.1 - 4.1e-36 121.8 37.5 9.3e-09 35.3 0.7 7.4 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 RJW65793.1 - 2.3e-21 75.0 40.5 0.00031 21.0 1.8 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW65793.1 - 5.8e-16 57.8 39.2 0.0089 16.8 1.9 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW65793.1 - 1.9e-07 31.2 8.3 0.37 11.1 0.1 5.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW65793.1 - 2.2e-05 24.3 27.2 0.17 11.9 1.8 6.5 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW65793.1 - 0.0024 17.6 18.1 0.21 11.4 0.1 4.7 4 0 0 4 4 4 2 zinc-finger C2H2-type Serinc PF03348.15 RJW65793.1 - 0.076 11.9 0.6 0.12 11.2 0.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Baculo_IE-1 PF05290.11 RJW65793.1 - 0.2 11.6 2.6 2 8.4 0.0 2.8 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_3rep PF18868.1 RJW65793.1 - 0.28 11.9 10.7 1.3 9.7 0.6 4.0 2 2 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 RJW65793.1 - 0.4 11.1 29.6 0.35 11.3 0.6 6.2 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 RJW65793.1 - 1.4 8.9 12.9 0.026 14.4 2.2 3.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF1117 PF06547.12 RJW65794.1 - 0.15 12.6 0.4 0.43 11.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) DFRP_C PF16543.5 RJW65795.1 - 2.7e-19 69.4 1.2 2.7e-19 69.4 1.2 2.9 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 RJW65795.1 - 1.2e-07 31.4 6.7 1.9e-05 24.4 0.7 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RJW65795.1 - 8.4e-07 29.7 11.5 3.1e-05 24.6 2.6 2.9 2 2 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 RJW65795.1 - 2.5e-06 27.4 5.2 2.5e-06 27.4 5.2 3.8 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 RJW65795.1 - 1.8e-05 24.4 0.8 1.8e-05 24.4 0.8 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RJW65795.1 - 0.0011 19.4 12.0 0.0083 16.6 2.2 2.8 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RJW65795.1 - 0.0016 18.6 0.5 0.18 12.1 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger containing family Branch PF02485.21 RJW65796.1 - 2.7e-29 102.4 0.0 3.8e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Sec31 PF11549.8 RJW65796.1 - 0.087 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein transport protein SEC31 Serpin PF00079.20 RJW65797.1 - 4.6e-93 312.5 3.1 5.2e-93 312.3 3.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) UQ_con PF00179.26 RJW65798.1 - 5.8e-11 42.2 0.1 9.8e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RVT_1 PF00078.27 RJW65798.1 - 0.0018 17.9 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 RJW65799.1 - 2.7e-42 144.8 0.0 4.9e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3983 PF13137.6 RJW65800.1 - 0.045 13.6 1.1 70 3.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3983) ABM PF03992.16 RJW65800.1 - 0.15 12.2 0.4 55 4.0 0.1 3.2 2 1 1 3 3 3 0 Antibiotic biosynthesis monooxygenase Metal_resist PF13801.6 RJW65800.1 - 0.2 11.9 4.2 44 4.3 0.1 3.1 1 1 2 3 3 3 0 Heavy-metal resistance TFIID-31kDa PF02291.15 RJW65800.1 - 0.2 11.7 0.1 50 4.0 0.0 2.8 2 1 1 3 3 3 0 Transcription initiation factor IID, 31kD subunit ComGG PF14173.6 RJW65800.1 - 0.23 11.9 2.1 6.7 7.2 0.0 2.9 3 0 0 3 3 3 0 ComG operon protein 7 TPR_2 PF07719.17 RJW65801.1 - 1.8e-06 27.6 5.4 0.63 10.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RJW65801.1 - 5e-06 26.1 4.1 0.43 10.5 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 RJW65801.1 - 0.00039 20.4 0.6 5.3 7.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW65801.1 - 0.001 19.3 10.4 0.0051 17.1 1.3 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 RJW65801.1 - 0.0067 16.3 4.2 0.57 10.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RJW65801.1 - 0.011 15.8 0.0 0.054 13.6 0.0 2.2 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 RJW65801.1 - 0.018 15.0 3.1 0.58 10.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat UQ_con PF00179.26 RJW65802.1 - 3e-26 91.8 0.0 4.9e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RJW65802.1 - 0.037 14.3 0.1 0.076 13.3 0.1 1.8 1 1 0 1 1 1 0 RWD domain Glycos_transf_2 PF00535.26 RJW65803.1 - 8.9e-32 110.2 0.0 1.5e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RJW65803.1 - 3.2e-15 56.5 0.4 2.6e-14 53.5 0.3 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 RJW65803.1 - 0.014 15.1 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase dsrm PF00035.26 RJW65804.1 - 1.9e-13 50.9 1.9 0.011 16.4 0.0 5.2 5 0 0 5 5 5 4 Double-stranded RNA binding motif RVT_1 PF00078.27 RJW65804.1 - 1.3e-09 37.9 0.0 5.4e-05 22.8 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DND1_DSRM PF14709.7 RJW65804.1 - 4.5e-05 23.6 0.7 0.03 14.6 0.1 4.2 3 1 0 3 3 3 1 double strand RNA binding domain from DEAD END PROTEIN 1 Branch PF02485.21 RJW65805.1 - 1.8e-34 119.4 0.4 2.7e-34 118.8 0.4 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme MULE PF10551.9 RJW65806.1 - 1.4e-06 28.6 0.0 1.9e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 MULE transposase domain Avl9 PF09794.9 RJW65807.1 - 9.3e-61 205.6 0.0 1.5e-57 195.1 0.0 2.5 2 1 0 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 RJW65807.1 - 4.1e-05 23.3 0.4 0.0024 17.5 0.4 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 RJW65807.1 - 0.00018 22.0 0.0 0.00035 21.0 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 RJW65807.1 - 0.14 12.0 0.3 0.61 10.0 0.1 2.0 1 1 0 1 1 1 0 DENN (AEX-3) domain YTH PF04146.15 RJW65808.1 - 5.8e-40 136.9 0.1 1.2e-39 135.9 0.1 1.6 1 0 0 1 1 1 1 YT521-B-like domain EGF PF00008.27 RJW65809.1 - 0.016 15.5 21.9 1.1 9.7 0.1 5.4 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.7 RJW65809.1 - 1.7 9.4 22.1 0.84 10.4 0.6 5.7 5 0 0 5 5 5 0 Human growth factor-like EGF PDZ PF00595.24 RJW65812.1 - 1.5e-30 105.4 0.2 1.1e-10 41.7 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Par3_HAL_N_term PF12053.8 RJW65812.1 - 8.7e-24 83.6 0.3 2e-23 82.4 0.3 1.6 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins PDZ_6 PF17820.1 RJW65812.1 - 3.2e-20 71.7 1.6 1.8e-06 27.7 0.1 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 RJW65812.1 - 5.2e-12 45.9 0.3 0.0022 18.3 0.0 4.0 3 0 0 3 3 3 3 PDZ domain Glycos_transf_2 PF00535.26 RJW65814.1 - 2.6e-32 112.0 0.0 1.1e-31 109.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RJW65814.1 - 1.3e-19 70.7 0.4 2.7e-19 69.7 0.4 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 RJW65814.1 - 1.3e-05 24.7 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF4058 PF13267.6 RJW65814.1 - 0.042 13.3 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) Helicase_C PF00271.31 RJW65815.1 - 0.069 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain E1_DerP2_DerF2 PF02221.15 RJW65817.1 - 6.8e-15 55.7 0.0 8e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 ML domain Nt_Gln_amidase PF09764.9 RJW65818.1 - 4.1e-48 163.4 0.0 6.2e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 N-terminal glutamine amidase DUF4325 PF14213.6 RJW65818.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) Neur_chan_LBD PF02931.23 RJW65820.1 - 3.4e-09 36.5 0.2 7e-09 35.4 0.2 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1989 PF09347.10 RJW65820.1 - 0.037 13.7 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) CxxCxxCC PF03692.15 RJW65820.1 - 0.057 14.1 0.6 0.16 12.7 0.6 1.7 1 0 0 1 1 1 0 Putative zinc- or iron-chelating domain MH2 PF03166.14 RJW65821.1 - 2.2e-66 223.7 0.1 4.6e-66 222.6 0.1 1.6 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.9 RJW65821.1 - 0.00029 20.7 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4801 PF16059.5 RJW65823.1 - 0.016 15.2 0.7 2.3 8.2 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4801) zf-C2HC_2 PF13913.6 RJW65824.1 - 1e-08 34.9 16.5 2.8e-05 23.9 1.4 3.2 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.6 RJW65824.1 - 0.0031 16.9 0.7 0.0031 16.9 0.7 4.0 4 0 0 4 4 4 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 RJW65824.1 - 0.006 16.3 2.8 0.006 16.3 2.8 3.3 3 0 0 3 3 3 1 zinc-ribbon domain DZR PF12773.7 RJW65824.1 - 0.016 15.2 1.1 0.016 15.2 1.1 3.8 4 1 0 4 4 4 0 Double zinc ribbon PLATZ PF04640.14 RJW65824.1 - 0.16 12.6 2.2 16 6.2 0.6 3.3 2 0 0 2 2 2 0 PLATZ transcription factor MqsA_antitoxin PF15731.5 RJW65824.1 - 0.16 12.1 0.6 11 6.1 0.1 2.7 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA UPF0547 PF10571.9 RJW65824.1 - 0.31 11.2 5.3 1.3 9.2 2.1 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 HypA PF01155.19 RJW65824.1 - 2.2 8.3 6.2 6.6 6.8 0.5 3.3 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_4 PF13894.6 RJW65824.1 - 5.3 8.1 14.7 0.37 11.8 0.9 4.5 3 1 0 3 3 3 0 C2H2-type zinc finger Ras PF00071.22 RJW65825.1 - 1.8e-44 151.2 0.0 2.6e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW65825.1 - 8.9e-25 87.2 0.0 1.5e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW65825.1 - 6.6e-08 32.2 0.0 9.1e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW65825.1 - 0.0046 16.5 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RJW65825.1 - 0.046 13.1 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region KTI12 PF08433.10 RJW65826.1 - 2.7e-56 191.0 0.0 4.6e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 WD40 PF00400.32 RJW65826.1 - 1.3e-23 82.8 15.9 0.00038 21.2 0.1 8.6 8 0 0 8 8 8 5 WD domain, G-beta repeat AAA_33 PF13671.6 RJW65826.1 - 1e-09 38.7 0.0 2.7e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Nup160 PF11715.8 RJW65826.1 - 0.0081 14.9 4.9 0.019 13.7 0.0 3.0 3 1 1 4 4 4 1 Nucleoporin Nup120/160 AAA_28 PF13521.6 RJW65826.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RJW65826.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PAN_1 PF00024.26 RJW65829.1 - 1 9.4 13.2 1.5 8.8 4.9 2.6 1 1 2 3 3 3 0 PAN domain HLH PF00010.26 RJW65830.1 - 3.3e-15 55.8 1.7 6.9e-15 54.7 1.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 RJW65830.1 - 0.0087 17.2 7.7 0.019 16.1 3.7 3.0 2 1 0 2 2 2 1 Neuronal helix-loop-helix transcription factor PINIT PF14324.6 RJW65832.1 - 3.9e-25 88.9 0.0 8.7e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 RJW65832.1 - 1.9e-20 72.3 5.5 1.9e-20 72.3 5.5 2.0 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 RJW65832.1 - 2.9e-05 23.8 2.5 2.9e-05 23.8 2.5 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Asp PF00026.23 RJW65833.1 - 1.1e-42 146.6 0.0 1.2e-42 146.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW65833.1 - 0.03 14.5 0.0 1.5 9.1 0.0 2.3 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 RJW65833.1 - 0.069 13.7 0.0 0.47 11.1 0.0 2.4 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RJW65833.1 - 0.13 12.9 0.0 1.2 9.8 0.0 2.5 3 0 0 3 3 3 0 Aspartyl protease TAXi_C PF14541.6 RJW65833.1 - 0.13 12.0 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Branch PF02485.21 RJW65835.1 - 1.6e-31 109.7 0.0 2.6e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme TPD52 PF04201.15 RJW65836.1 - 1.2e-20 73.7 1.7 1.3e-20 73.6 1.7 1.0 1 0 0 1 1 1 1 Tumour protein D52 family FapA PF03961.13 RJW65836.1 - 0.0074 14.9 0.7 0.0087 14.7 0.7 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A Enkurin PF13864.6 RJW65836.1 - 0.019 15.4 0.8 0.019 15.4 0.8 2.1 1 1 0 2 2 2 0 Calmodulin-binding Macoilin PF09726.9 RJW65836.1 - 0.022 13.4 0.3 0.022 13.3 0.3 1.1 1 0 0 1 1 1 0 Macoilin family SlyX PF04102.12 RJW65836.1 - 0.031 14.9 3.5 0.063 13.9 3.5 1.5 1 0 0 1 1 1 0 SlyX kleA_kleC PF17383.2 RJW65836.1 - 0.035 14.4 1.1 0.083 13.2 0.7 2.0 1 1 0 1 1 1 0 Uncharacterized KorC regulated protein A DUF4407 PF14362.6 RJW65836.1 - 0.036 13.4 3.6 0.041 13.2 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 RJW65836.1 - 0.04 14.5 5.0 2.6 8.7 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Siah-Interact_N PF09032.11 RJW65836.1 - 0.042 14.2 1.3 0.042 14.2 1.3 1.7 2 0 0 2 2 2 0 Siah interacting protein, N terminal LRS4 PF10422.9 RJW65836.1 - 0.057 13.0 1.9 0.076 12.6 1.3 1.4 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 GrpE PF01025.19 RJW65836.1 - 0.14 11.8 4.6 0.11 12.1 3.7 1.4 1 1 0 1 1 1 0 GrpE APG6_N PF17675.1 RJW65836.1 - 0.42 11.1 7.5 0.14 12.7 3.6 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region YtxH PF12732.7 RJW65836.1 - 2.4 8.8 7.0 43 4.7 7.0 2.2 1 1 0 1 1 1 0 YtxH-like protein bZIP_2 PF07716.15 RJW65836.1 - 8.3 6.6 9.3 0.36 11.0 3.0 2.0 2 1 0 2 2 2 0 Basic region leucine zipper RVT_1 PF00078.27 RJW65838.1 - 1.9e-85 285.9 0.0 3.9e-44 150.8 0.0 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW65838.1 - 6.8e-11 42.1 6.4 5e-06 26.2 0.4 4.1 5 0 0 5 5 5 2 Endonuclease/Exonuclease/phosphatase family UBX PF00789.20 RJW65838.1 - 1.4e-08 34.8 0.1 6.1e-08 32.8 0.1 2.1 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 RJW65838.1 - 7.6e-08 32.0 0.9 2.3e-07 30.5 0.2 2.2 2 0 0 2 2 2 1 UBA-like domain DUF2656 PF10847.8 RJW65838.1 - 0.026 14.6 0.0 1.5 8.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2656) DUF1296 PF06972.11 RJW65838.1 - 0.028 14.6 0.0 0.065 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) DUF1759 PF03564.15 RJW65840.1 - 0.042 13.8 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Asp_protease_2 PF13650.6 RJW65840.1 - 0.089 13.4 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease MIT PF04212.18 RJW65842.1 - 5.9e-20 71.1 1.9 7.5e-20 70.8 1.9 1.1 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 RJW65842.1 - 0.03 14.1 1.2 0.06 13.2 1.1 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 RJW65842.1 - 0.097 12.8 1.8 0.21 11.8 1.6 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 RJW65843.1 - 1.9e-13 50.0 38.5 0.00013 22.2 2.9 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW65843.1 - 4.1e-12 45.8 42.0 0.00034 21.2 2.9 6.0 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.7 RJW65843.1 - 5.1e-05 23.5 16.3 0.0078 16.6 0.2 4.9 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RJW65843.1 - 7e-05 22.5 10.0 0.0013 18.4 1.8 5.7 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 RJW65843.1 - 0.00025 21.3 36.4 0.16 12.5 1.0 6.5 6 1 0 6 6 5 3 Zinc-finger double domain zf-C2H2_3rep PF18868.1 RJW65843.1 - 0.0053 17.4 12.7 0.63 10.7 4.3 2.9 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 RJW65843.1 - 0.0063 16.8 0.6 0.0063 16.8 0.6 4.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 RJW65843.1 - 0.028 14.3 20.0 0.27 11.2 1.2 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 RJW65843.1 - 0.032 14.7 0.1 0.032 14.7 0.1 3.8 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_15 PF17032.5 RJW65843.1 - 0.053 14.3 11.7 8.1 7.3 6.1 3.6 1 1 3 4 4 4 0 zinc-ribbon family zf-C2H2_6 PF13912.6 RJW65843.1 - 0.18 11.8 0.2 0.18 11.8 0.2 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger ADK_lid PF05191.14 RJW65843.1 - 0.32 11.0 8.5 6.3 6.9 2.4 3.4 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-Di19 PF05605.12 RJW65843.1 - 0.94 9.8 25.3 0.34 11.2 6.6 3.5 1 1 3 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 RJW65843.1 - 2.6 8.3 14.5 4.9 7.4 3.9 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf_UBZ PF18439.1 RJW65843.1 - 3.8 7.2 17.2 17 5.1 0.6 5.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 RJW65843.1 - 5.9 7.2 11.5 12 6.3 0.1 3.9 4 0 0 4 4 3 0 zinc-ribbon zf-RING_7 PF02591.15 RJW65843.1 - 9 6.6 10.2 7.5 6.8 0.2 4.0 4 0 0 4 4 4 0 C4-type zinc ribbon domain PDZ PF00595.24 RJW65844.1 - 4.2e-55 184.0 0.1 2.2e-13 50.4 0.0 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 RJW65844.1 - 8.2e-34 115.2 3.9 4e-08 33.0 0.9 5.3 5 0 0 5 5 5 4 PDZ domain PDZ_2 PF13180.6 RJW65844.1 - 6.2e-19 68.1 0.0 3.6e-05 24.0 0.0 4.4 4 0 0 4 4 4 3 PDZ domain zf-C3HC4 PF00097.25 RJW65844.1 - 4.3e-06 26.5 6.2 1.9e-05 24.5 6.2 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW65844.1 - 5.8e-06 26.2 8.0 5.8e-06 26.2 8.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RJW65844.1 - 4.2e-05 23.3 7.4 4.2e-05 23.3 7.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW65844.1 - 9.4e-05 22.2 3.3 0.00039 20.2 3.3 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RJW65844.1 - 0.00013 22.1 5.4 0.00067 19.8 5.4 2.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RJW65844.1 - 0.00046 20.1 5.3 0.00046 20.1 5.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-TRAF_2 PF15965.5 RJW65844.1 - 0.0011 19.4 3.0 0.0011 19.4 3.0 2.5 1 1 1 2 2 2 1 TRAF-like zinc-finger Tricorn_PDZ PF14685.6 RJW65844.1 - 0.0016 18.4 0.1 2.2 8.3 0.0 3.5 4 0 0 4 4 4 1 Tricorn protease PDZ domain zf-TRAF PF02176.18 RJW65844.1 - 0.0054 17.4 0.7 0.0054 17.4 0.7 2.1 2 0 0 2 2 1 1 TRAF-type zinc finger zf-RING_2 PF13639.6 RJW65844.1 - 0.0055 17.0 5.2 0.0055 17.0 5.2 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.5 RJW65844.1 - 0.0089 16.1 7.2 0.028 14.5 7.2 1.9 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 RJW65844.1 - 0.55 10.6 8.8 4.6 7.6 9.0 2.6 1 1 1 2 2 2 0 RING-H2 zinc finger domain Ank PF00023.30 RJW65846.1 - 0.00019 21.7 0.0 0.00047 20.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 RJW65846.1 - 0.0027 18.2 0.0 0.0048 17.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) MORN PF02493.20 RJW65848.1 - 2e-42 140.6 67.7 2.7e-08 33.2 2.9 9.6 9 0 0 9 9 9 9 MORN repeat Pdase_C33_assoc PF14756.6 RJW65848.1 - 0.029 14.3 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase_C33-associated domain Cdc13_OB2 PF18691.1 RJW65848.1 - 0.042 13.9 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Cell division control protein 13, OB2 domain TAF8_C PF10406.9 RJW65849.1 - 1.2e-13 51.3 0.9 2.3e-13 50.5 0.9 1.5 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 RJW65849.1 - 3.8e-07 30.0 0.0 6.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PAP2 PF01569.21 RJW65850.1 - 8.3e-07 28.8 5.0 1.4e-06 28.1 5.0 1.3 1 0 0 1 1 1 1 PAP2 superfamily LSM PF01423.22 RJW65853.1 - 1.3e-17 63.2 0.2 1.7e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF2986 PF11661.8 RJW65853.1 - 3.1 8.4 7.4 0.73 10.4 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) DUF1839 PF08893.10 RJW65854.1 - 0.18 11.0 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) DUF2256 PF10013.9 RJW65858.1 - 0.24 11.5 0.3 0.24 11.5 0.3 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) HMG_box PF00505.19 RJW65860.1 - 7e-10 39.2 0.1 1.8e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW65860.1 - 1.9e-07 31.6 0.2 5.6e-07 30.1 0.2 1.8 1 0 0 1 1 1 1 HMG-box domain PIN_8 PF18476.1 RJW65860.1 - 0.0051 16.7 3.8 0.0051 16.7 3.8 1.9 1 1 1 2 2 2 1 PIN like domain P22_AR_C PF10548.9 RJW65860.1 - 0.016 15.3 0.6 1.9 8.7 0.0 2.5 2 1 0 2 2 2 0 P22AR C-terminal domain MlaC PF05494.12 RJW65860.1 - 0.037 13.8 2.3 0.21 11.3 0.1 2.4 2 0 0 2 2 2 0 MlaC protein UNC-79 PF14776.6 RJW65860.1 - 0.042 12.6 0.3 0.054 12.3 0.3 1.3 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 CNOT11 PF10155.9 RJW65860.1 - 0.12 12.5 2.3 0.18 11.9 0.3 2.0 1 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 CENP-H PF05837.12 RJW65860.1 - 0.22 11.9 10.8 0.038 14.4 3.4 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) IL11 PF07400.11 RJW65860.1 - 0.24 11.0 9.4 0.35 10.5 2.0 2.8 2 1 1 3 3 3 0 Interleukin 11 Atg14 PF10186.9 RJW65860.1 - 1.1 8.3 7.8 1.4 7.9 7.8 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT20 PF14931.6 RJW65860.1 - 1.2 9.3 9.6 0.13 12.5 3.1 2.4 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 KxDL PF10241.9 RJW65860.1 - 3.5 8.0 9.5 22 5.4 4.8 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein FliD_N PF02465.18 RJW65860.1 - 5.5 7.7 8.1 3.3 8.5 4.2 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus RhoGEF PF00621.20 RJW65861.1 - 1.2e-27 97.4 0.1 6e-27 95.1 0.0 2.4 2 0 0 2 2 2 1 RhoGEF domain Spectrin PF00435.21 RJW65861.1 - 4.3e-17 62.5 26.3 3.1e-05 24.4 1.5 7.4 6 1 0 6 6 6 4 Spectrin repeat PH PF00169.29 RJW65861.1 - 3.1e-05 24.4 0.1 0.00012 22.5 0.1 2.0 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 RJW65861.1 - 0.00087 19.5 0.0 0.0031 17.7 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 RJW65861.1 - 0.016 15.2 0.3 0.054 13.5 0.0 2.0 2 0 0 2 2 2 0 PH domain Syntaxin-6_N PF09177.11 RJW65861.1 - 5.4 7.6 11.9 1.6 9.3 0.8 5.4 6 1 0 6 6 6 0 Syntaxin 6, N-terminal Adaptin_binding PF10199.9 RJW65863.1 - 9.8e-11 42.3 0.6 1.7e-10 41.5 0.6 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ribonuc_P_40 PF08584.11 RJW65863.1 - 0.068 12.4 0.1 0.091 12.0 0.1 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit IQ PF00612.27 RJW65864.1 - 7.8e-16 56.3 18.8 3.3e-07 29.5 1.1 4.1 3 0 0 3 3 3 3 IQ calmodulin-binding motif Innexin PF00876.18 RJW65867.1 - 6.5e-67 226.3 2.7 7.3e-67 226.1 2.7 1.0 1 0 0 1 1 1 1 Innexin Peptidase_C33 PF05412.12 RJW65867.1 - 0.091 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase DUF3278 PF11683.8 RJW65867.1 - 0.24 11.5 2.2 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) C2 PF00168.30 RJW65868.1 - 2.7e-24 85.4 1.2 5.9e-11 42.6 0.0 3.6 4 0 0 4 4 4 3 C2 domain FerI PF08151.12 RJW65868.1 - 1.8e-15 56.7 0.1 3.6e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 FerI (NUC094) domain Menin PF05053.13 RJW65870.1 - 1.3e-92 311.3 0.7 2.7e-43 148.3 0.0 7.1 7 0 0 7 7 7 6 Menin TPR_2 PF07719.17 RJW65870.1 - 6.5 7.1 6.2 0.87 9.9 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RJW65870.1 - 9.9 6.5 6.0 3.7 7.9 0.5 2.8 3 1 1 4 4 4 0 Tetratricopeptide repeat E1_DerP2_DerF2 PF02221.15 RJW65871.1 - 2.1e-10 41.2 0.5 2.6e-10 40.9 0.5 1.1 1 0 0 1 1 1 1 ML domain ANAPC4_WD40 PF12894.7 RJW65872.1 - 1.2e-08 35.2 0.1 0.0031 17.8 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW65872.1 - 2e-06 28.4 12.3 0.071 14.0 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat LisH_TPL PF17814.1 RJW65872.1 - 0.00054 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain eIF2A PF08662.11 RJW65872.1 - 0.021 14.7 0.0 0.057 13.3 0.0 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RJW65872.1 - 0.054 13.4 0.1 16 5.6 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Tim54 PF11711.8 RJW65874.1 - 0.14 10.9 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 RJW65874.1 - 0.18 11.8 8.8 0.16 11.9 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 RJW65874.1 - 0.3 11.1 5.0 0.36 10.9 5.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TFB6 PF17110.5 RJW65874.1 - 5.3 6.8 9.6 58 3.4 7.8 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 RJW65875.1 - 8.2e-05 22.3 0.2 9e-05 22.2 0.2 1.1 1 0 0 1 1 1 1 FAM176 family PBP1_TM PF14812.6 RJW65875.1 - 0.13 12.6 17.9 0.21 12.0 17.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 RJW65875.1 - 0.2 11.6 7.2 0.22 11.6 7.2 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 RJW65875.1 - 0.24 10.7 17.2 0.27 10.5 17.2 1.1 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 RJW65875.1 - 0.41 10.5 7.9 0.48 10.3 7.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 RJW65875.1 - 0.43 8.8 9.6 0.5 8.6 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein XAP5 PF04921.14 RJW65875.1 - 0.66 9.7 5.7 0.82 9.4 5.7 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Cwf_Cwc_15 PF04889.12 RJW65875.1 - 0.8 9.4 17.6 0.92 9.2 17.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 RJW65875.1 - 0.96 8.5 21.7 1.1 8.3 21.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 RJW65875.1 - 1.4 6.9 15.5 1.5 6.8 15.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 RJW65875.1 - 1.5 6.8 6.8 1.6 6.7 6.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 RJW65875.1 - 2.1 6.8 10.1 2.2 6.7 10.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SGT1 PF07093.11 RJW65875.1 - 2.7 6.3 7.4 2.9 6.2 7.4 1.0 1 0 0 1 1 1 0 SGT1 protein CENP-B_dimeris PF09026.10 RJW65875.1 - 3.2 8.2 23.1 4.3 7.8 23.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 RJW65875.1 - 4.9 6.7 11.1 5.4 6.6 11.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 RJW65875.1 - 9.3 4.3 12.4 9.7 4.3 12.4 1.0 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 RJW65875.1 - 9.9 6.2 12.6 11 6.0 12.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF2798 PF11391.8 RJW65876.1 - 0.095 12.8 39.1 1.8e+04 -24.6 39.1 5.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) Colicin_V PF02674.16 RJW65876.1 - 0.14 12.2 44.8 1.8e+04 -12.2 44.8 3.6 1 1 0 1 1 1 0 Colicin V production protein DUF2428 PF10350.9 RJW65879.1 - 1.1e-23 83.9 0.2 5.3e-23 81.6 0.2 2.2 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) VHL PF01847.16 RJW65880.1 - 0.036 14.0 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 VHL beta domain Herpes_U26 PF07402.11 RJW65880.1 - 0.081 12.5 0.0 0.094 12.3 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus U26 protein Innexin PF00876.18 RJW65882.1 - 1.1e-101 340.7 2.8 1.4e-101 340.4 2.8 1.1 1 0 0 1 1 1 1 Innexin Ycf9 PF01737.17 RJW65882.1 - 0.017 15.0 5.6 1 9.3 0.0 2.7 2 0 0 2 2 2 0 YCF9 PhoLip_ATPase_C PF16212.5 RJW65884.1 - 1.4e-55 188.7 21.6 2.1e-55 188.2 21.6 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 RJW65884.1 - 4.2e-11 43.5 0.9 1.7e-05 25.2 0.0 3.5 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RJW65884.1 - 2.7e-06 27.4 0.0 2.8e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RJW65884.1 - 0.032 13.9 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 RJW65884.1 - 0.035 14.5 0.1 12 6.3 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PHP_C PF13263.6 RJW65884.1 - 0.1 12.4 0.0 0.37 10.6 0.0 1.9 1 0 0 1 1 1 0 PHP-associated Peptidase_M1 PF01433.20 RJW65885.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 2 0 0 2 2 2 0 Peptidase family M1 domain Peptidase_M3 PF01432.20 RJW65886.1 - 3.9e-14 52.8 0.0 1.4e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 Omp_AT PF11557.8 RJW65886.1 - 0.063 12.2 0.1 3 6.7 0.0 2.1 2 0 0 2 2 2 0 Solitary outer membrane autotransporter beta-barrel domain Innexin PF00876.18 RJW65887.1 - 2.6e-69 234.2 0.0 3.8e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Innexin SelP_N PF04592.14 RJW65887.1 - 3.4 7.0 7.3 5 6.4 7.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Galactosyl_T PF01762.21 RJW65888.1 - 1.3e-05 25.1 0.1 0.00033 20.5 0.1 2.1 1 1 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 RJW65888.1 - 0.032 13.7 0.2 0.075 12.4 0.2 1.6 1 1 0 1 1 1 0 Fringe-like E1_DerP2_DerF2 PF02221.15 RJW65889.1 - 0.0011 19.4 0.0 0.0011 19.4 0.0 1.0 1 0 0 1 1 1 1 ML domain Asp PF00026.23 RJW65891.1 - 3.7e-06 26.6 0.0 4.7e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease RhoGAP PF00620.27 RJW65892.1 - 1.1e-38 132.4 1.1 8.5e-38 129.6 0.0 2.8 3 0 0 3 3 3 1 RhoGAP domain C2 PF00168.30 RJW65892.1 - 3.5e-07 30.4 0.1 1.2e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 C2 domain DOCK-C2 PF14429.6 RJW65892.1 - 0.033 14.0 0.1 0.081 12.7 0.1 1.6 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins DUF16 PF01519.16 RJW65892.1 - 3.9 8.0 8.0 0.56 10.7 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function DUF16 BRE1 PF08647.11 RJW65892.1 - 5.1 7.2 11.7 0.5 10.5 0.2 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DAO PF01266.24 RJW65893.1 - 8.4e-40 137.4 0.0 1.5e-39 136.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 RJW65893.1 - 4.4e-39 133.2 0.0 9e-39 132.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 RJW65893.1 - 4.7e-12 46.2 0.4 9.1e-12 45.3 0.4 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW65893.1 - 3.5e-07 30.0 0.2 8.4e-07 28.7 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW65893.1 - 2e-05 23.8 0.1 0.0091 15.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW65893.1 - 0.00039 20.1 0.1 0.28 11.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 RJW65893.1 - 0.00052 20.1 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand DUF5580 PF17743.1 RJW65893.1 - 0.052 12.1 0.1 0.07 11.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_5 PF13202.6 RJW65893.1 - 0.086 12.4 0.1 0.43 10.2 0.1 2.1 2 0 0 2 2 2 0 EF hand RVT_1 PF00078.27 RJW65894.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAO PF01266.24 RJW65894.1 - 0.0059 16.2 0.1 0.0092 15.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase SDA1 PF05285.12 RJW65894.1 - 0.029 13.8 11.3 0.042 13.3 11.3 1.2 1 0 0 1 1 1 0 SDA1 Pyr_redox_2 PF07992.14 RJW65894.1 - 0.039 13.2 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TRAP_alpha PF03896.16 RJW65894.1 - 0.043 13.0 4.5 0.064 12.5 4.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 RJW65894.1 - 0.09 10.9 28.4 0.13 10.4 28.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 RJW65894.1 - 0.15 10.5 8.4 0.17 10.3 7.4 1.5 2 0 0 2 2 2 0 Mpp10 protein BUD22 PF09073.10 RJW65894.1 - 0.15 11.4 8.0 0.18 11.1 8.0 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 RJW65894.1 - 0.15 11.6 8.0 0.21 11.2 8.0 1.2 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 RJW65894.1 - 0.18 10.3 12.7 0.24 9.9 12.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GIDA PF01134.22 RJW65894.1 - 0.29 10.2 1.0 1.1 8.2 1.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 RJW65894.1 - 0.4 9.7 2.1 0.56 9.2 2.1 1.1 1 0 0 1 1 1 0 FAD binding domain zf-C2H2_10 PF16588.5 RJW65894.1 - 1.1 9.0 3.7 0.42 10.4 0.3 1.9 2 0 0 2 2 2 0 C2H2 zinc-finger FAD_oxidored PF12831.7 RJW65894.1 - 1.2 8.5 2.6 1.9 7.8 2.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Tom22 PF04281.13 RJW65894.1 - 1.4 8.7 6.1 2.6 7.8 6.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TFIIA PF03153.13 RJW65894.1 - 1.7 8.6 17.5 2.1 8.3 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 RJW65894.1 - 2 6.5 17.6 2.8 6.1 17.6 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 RJW65894.1 - 2.4 8.3 21.4 4.1 7.6 21.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFB6 PF17110.5 RJW65894.1 - 2.9 7.6 7.5 4.7 6.9 7.5 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2722 PF10846.8 RJW65894.1 - 3.8 6.4 8.7 5 5.9 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sigma70_ner PF04546.13 RJW65894.1 - 5.2 6.9 13.9 8.8 6.1 13.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1759 PF03564.15 RJW65895.1 - 1.5e-10 41.2 0.0 3.2e-10 40.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) ARID PF01388.21 RJW65896.1 - 2.6e-19 69.7 0.1 5.8e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Glycos_transf_2 PF00535.26 RJW65897.1 - 1.2e-24 87.0 0.0 1.9e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RJW65897.1 - 6.3e-16 58.8 0.1 2e-15 57.2 0.0 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 RJW65897.1 - 1.3e-07 31.2 0.0 2.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 RJW65897.1 - 0.00022 21.2 0.0 0.00056 19.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 RJW65897.1 - 0.0013 18.2 0.0 0.0082 15.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF1205 PF06722.12 RJW65899.1 - 0.082 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) EF-hand_6 PF13405.6 RJW65900.1 - 1.5e-09 37.0 5.5 0.0011 18.7 0.2 4.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 RJW65900.1 - 1.2e-07 30.7 5.4 0.023 14.2 0.1 4.6 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 RJW65900.1 - 1.5e-07 31.7 1.0 0.003 18.0 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW65900.1 - 0.012 15.1 0.5 10 5.8 0.0 3.7 3 0 0 3 3 3 0 EF hand EFhand_Ca_insen PF08726.10 RJW65900.1 - 0.012 15.7 0.1 0.23 11.6 0.0 2.8 2 1 0 2 2 2 0 Ca2+ insensitive EF hand PH PF00169.29 RJW65901.1 - 0.016 15.7 0.1 0.034 14.7 0.1 1.6 1 0 0 1 1 1 0 PH domain RT_RNaseH PF17917.1 RJW65902.1 - 2.7e-13 50.1 0.0 3.9e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW65902.1 - 1.1e-06 28.6 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CAP PF00188.26 RJW65903.1 - 5.7e-11 43.3 0.2 1.2e-10 42.3 0.2 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family EBP PF05241.12 RJW65903.1 - 0.07 12.6 0.0 0.085 12.3 0.0 1.1 1 0 0 1 1 1 0 Emopamil binding protein SRP40_C PF05022.12 RJW65905.1 - 3.7e-23 82.2 0.5 7.7e-23 81.1 0.5 1.6 1 0 0 1 1 1 1 SRP40, C-terminal domain Cation_ATPase_C PF00689.21 RJW65907.1 - 3.2e-43 147.6 5.9 5.5e-43 146.8 5.9 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RJW65907.1 - 2.4e-42 144.5 0.2 7.5e-42 142.9 0.2 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 RJW65907.1 - 9.5e-21 73.7 0.1 1.7e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RJW65907.1 - 8.7e-20 71.9 0.4 4.8e-19 69.5 0.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RJW65907.1 - 4.2e-06 26.7 2.5 5.9e-06 26.2 0.8 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RJW65907.1 - 5.5e-06 26.9 0.1 4e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HTH_AraC PF00165.23 RJW65908.1 - 0.013 15.6 0.7 0.028 14.5 0.7 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Fibrillin_U_N PF18193.1 RJW65910.1 - 0.066 13.3 2.0 0.15 12.2 2.0 1.6 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain Kinesin PF00225.23 RJW65912.1 - 2.6e-83 279.7 0.5 1.2e-82 277.6 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW65912.1 - 1e-45 155.3 2.5 3e-45 153.8 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding CRR7 PF12095.8 RJW65913.1 - 4.7 7.7 11.8 15 6.1 1.3 4.5 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 MH2 PF03166.14 RJW65914.1 - 5.5e-72 241.9 0.0 8.6e-72 241.3 0.0 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 RJW65914.1 - 1.3e-35 121.7 0.3 2.2e-35 120.9 0.3 1.4 1 0 0 1 1 1 1 MH1 domain Keratin_2_head PF16208.5 RJW65914.1 - 0.086 13.0 30.0 0.18 12.0 19.6 2.5 2 0 0 2 2 2 0 Keratin type II head UQ_con PF00179.26 RJW65918.1 - 1.1e-31 109.4 0.0 1.7e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RJW65918.1 - 0.0003 20.7 0.1 0.00092 19.1 0.0 1.8 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 RJW65918.1 - 0.045 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 RJW65918.1 - 0.11 12.8 0.2 0.28 11.5 0.2 1.8 1 1 0 1 1 1 0 RWD domain Glyco_transf_92 PF01697.27 RJW65920.1 - 5.5e-15 55.7 0.0 7.9e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_transf_92 PF01697.27 RJW65921.1 - 1.4e-28 100.2 0.0 2.3e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RJW65921.1 - 0.001 19.6 0.0 0.0062 17.0 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 zf-C2H2 PF00096.26 RJW65925.1 - 4.5e-16 58.3 45.3 0.0012 19.2 0.3 6.3 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW65925.1 - 3.3e-14 52.4 44.8 0.026 15.4 0.4 6.4 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW65925.1 - 2e-07 31.1 23.5 0.0026 18.0 0.2 6.1 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RJW65925.1 - 2e-06 28.0 38.6 0.0014 19.0 0.6 7.2 7 0 0 7 7 7 3 Zinc-finger double domain zf-met PF12874.7 RJW65925.1 - 0.00096 19.5 27.0 0.9 10.0 0.1 6.4 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 RJW65925.1 - 0.0065 16.9 0.7 0.0065 16.9 0.7 5.1 1 1 4 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 RJW65925.1 - 0.049 13.6 34.1 6 7.0 0.9 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger DUF2256 PF10013.9 RJW65925.1 - 0.12 12.5 0.4 0.12 12.5 0.4 5.6 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_3rep PF18868.1 RJW65925.1 - 0.58 10.8 23.1 2.3 8.9 2.8 4.1 2 2 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 RJW65925.1 - 1.1 9.0 35.6 4.2 7.2 2.9 6.0 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-B_box PF00643.24 RJW65925.1 - 1.7 8.9 30.6 0.078 13.2 4.9 5.6 2 2 3 5 5 5 0 B-box zinc finger zf-C2H2_2 PF12756.7 RJW65925.1 - 1.9 8.9 35.4 3.3 8.1 0.8 5.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 RJW65925.1 - 2 8.7 6.8 14 6.0 0.0 3.9 2 1 3 5 5 5 0 BolA-like protein DSHCT PF08148.12 RJW65926.1 - 4.4e-19 68.7 0.0 1.1e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 RJW65926.1 - 3.2e-17 62.8 0.0 1.1e-16 61.1 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 RJW65926.1 - 6.2e-12 46.0 2.1 3e-06 27.4 0.6 3.3 2 1 1 3 3 3 2 rRNA-processing arch domain Helicase_C PF00271.31 RJW65926.1 - 1.1e-06 29.0 0.1 2.5e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW65926.1 - 1.6e-05 25.0 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RJW65926.1 - 0.0038 17.5 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 RJW65926.1 - 0.12 11.9 0.3 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF1778 PF08681.11 RJW65926.1 - 0.68 9.9 2.6 3.5 7.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1778) Fe_hyd_lg_C PF02906.14 RJW65928.1 - 9.6e-47 159.7 0.0 1.6e-44 152.4 0.0 2.9 1 1 1 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain START PF01852.19 RJW65929.1 - 3e-28 98.7 0.2 9.4e-28 97.1 0.0 1.9 2 0 0 2 2 2 1 START domain GTP_EFTU PF00009.27 RJW65930.1 - 2.4e-32 112.1 3.5 2.3e-31 108.8 3.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RJW65930.1 - 1.7e-25 89.2 0.0 3.9e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 RJW65930.1 - 2.7e-08 33.9 0.0 4.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 RJW65930.1 - 0.00031 20.5 0.4 0.026 14.3 0.3 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 RJW65930.1 - 0.012 15.3 0.2 0.053 13.1 0.2 2.0 1 1 0 1 1 1 0 Ras family FeoB_N PF02421.18 RJW65930.1 - 0.013 15.1 0.7 0.2 11.1 0.7 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RJW65930.1 - 0.045 13.7 3.6 0.42 10.5 0.3 3.4 3 1 1 4 4 4 0 RsgA GTPase Roc PF08477.13 RJW65930.1 - 0.075 13.3 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 RJW65930.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 RJW65930.1 - 0.14 12.2 0.2 14 5.6 0.0 2.6 2 0 0 2 2 2 0 Dynamin family Glyco_transf_92 PF01697.27 RJW65932.1 - 1e-25 90.9 0.3 1.4e-25 90.4 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RJW65932.1 - 0.014 15.9 0.0 0.039 14.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 PDZ PF00595.24 RJW65933.1 - 6.8e-17 61.6 0.0 8.3e-09 35.7 0.0 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 RJW65933.1 - 4.4e-13 48.9 0.2 3e-05 23.8 0.1 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 RJW65933.1 - 4.9e-11 42.8 0.1 2.2e-08 34.3 0.1 3.1 3 0 0 3 3 3 2 PDZ domain SNAP-25 PF00835.19 RJW65934.1 - 5.6e-11 42.6 1.4 1.3e-10 41.4 1.4 1.7 1 0 0 1 1 1 1 SNAP-25 family DUF5089 PF17002.5 RJW65934.1 - 0.00094 19.1 6.7 0.07 13.0 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) DASH_Duo1 PF08651.10 RJW65934.1 - 0.002 17.8 2.8 0.42 10.4 0.0 3.2 3 1 1 4 4 4 2 DASH complex subunit Duo1 V-SNARE_C PF12352.8 RJW65934.1 - 0.0031 17.8 6.7 0.0069 16.7 0.3 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF16 PF01519.16 RJW65934.1 - 0.0077 16.7 8.9 0.23 12.0 1.0 2.4 2 1 0 2 2 2 2 Protein of unknown function DUF16 DUF948 PF06103.11 RJW65934.1 - 0.32 11.3 4.2 3.8 7.8 0.3 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 RJW65934.1 - 1.5 8.8 9.7 1.1 9.2 0.2 2.9 2 1 1 3 3 3 0 Laminin Domain II DivIC PF04977.15 RJW65934.1 - 7.4 6.4 9.4 3.1 7.6 0.6 2.7 3 0 0 3 3 3 0 Septum formation initiator BCDHK_Adom3 PF10436.9 RJW65935.1 - 6.2e-24 84.7 0.0 8.6e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RJW65935.1 - 2.8e-06 27.8 0.0 1.2e-05 25.8 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RJW65935.1 - 0.0017 18.2 0.0 0.0044 16.9 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PhoU_div PF01865.16 RJW65935.1 - 0.016 14.5 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF47 HMG_box_2 PF09011.10 RJW65936.1 - 6.3e-09 36.3 5.8 6.3e-09 36.3 5.8 2.0 1 1 1 2 2 2 1 HMG-box domain HMG_box PF00505.19 RJW65936.1 - 2.4e-07 31.1 9.4 1.2e-05 25.6 4.6 2.9 1 1 1 2 2 2 2 HMG (high mobility group) box baeRF_family12 PF18856.1 RJW65936.1 - 0.073 13.7 0.5 0.12 13.0 0.3 1.5 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 RVT_1 PF00078.27 RJW65937.1 - 7e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tim44 PF04280.15 RJW65939.1 - 2.9e-22 79.4 0.0 4.1e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain SNF2_N PF00176.23 RJW65942.1 - 4.5e-45 153.9 0.0 1.2e-43 149.2 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW65942.1 - 3.5e-15 56.3 0.0 1.2e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PDZ PF00595.24 RJW65942.1 - 1.7e-07 31.5 0.0 5.3e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 PDZ domain ResIII PF04851.15 RJW65942.1 - 0.00037 20.5 0.0 0.00088 19.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PDZ_6 PF17820.1 RJW65942.1 - 0.0028 17.5 0.3 0.02 14.7 0.0 2.6 3 0 0 3 3 3 1 PDZ domain TPR_12 PF13424.6 RJW65942.1 - 0.021 15.1 0.1 0.68 10.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RJW65942.1 - 0.04 14.0 0.0 13 6.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RJW65942.1 - 0.057 13.9 0.1 1.1 9.9 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-HC5HC2H_2 PF13832.6 RJW65944.1 - 2e-08 34.4 4.3 5.9e-05 23.2 3.9 2.3 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RJW65944.1 - 4.8e-06 26.7 3.0 4.8e-06 26.7 3.0 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain Tudor_2 PF18104.1 RJW65944.1 - 0.064 12.9 0.4 0.28 10.9 0.1 2.3 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain C1_1 PF00130.22 RJW65944.1 - 0.12 12.3 5.9 0.24 11.3 5.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Phage_stabilise PF11134.8 RJW65947.1 - 0.2 10.4 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Phage stabilisation protein PX PF00787.24 RJW65948.1 - 9.5e-15 54.6 0.0 2.4e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 PX domain zf-TAZ PF02135.16 RJW65948.1 - 0.99 9.9 4.2 31 5.1 0.1 3.0 3 0 0 3 3 3 0 TAZ zinc finger Med13_C PF06333.12 RJW65950.1 - 2.5e-68 230.8 0.2 1.1e-38 133.4 0.0 3.3 3 0 0 3 3 3 2 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 RJW65950.1 - 3.8e-15 56.4 0.0 1.6e-14 54.3 0.1 2.1 2 0 0 2 2 2 1 MID domain of medPIWI MerB PF03243.15 RJW65950.1 - 0.15 12.2 0.7 31 4.7 0.1 3.0 3 0 0 3 3 3 0 Alkylmercury lyase FapA PF03961.13 RJW65951.1 - 0.052 12.2 0.8 0.078 11.6 0.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 RJW65951.1 - 7.8 6.8 9.1 13 6.1 9.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tudor_2 PF18104.1 RJW65952.1 - 3.1 7.6 5.0 1.6 8.5 0.1 2.6 2 1 1 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Ank_2 PF12796.7 RJW65955.1 - 8.8e-29 99.9 15.2 1.1e-09 38.8 0.2 5.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW65955.1 - 8.7e-19 67.3 8.4 4.9e-06 26.7 0.1 6.3 1 1 7 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW65955.1 - 1.8e-18 66.6 11.0 2e-05 25.0 0.2 6.5 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW65955.1 - 2.4e-17 61.2 7.6 0.0022 18.4 0.0 8.1 8 0 0 8 8 8 3 Ankyrin repeat Patatin PF01734.22 RJW65955.1 - 4.3e-16 59.7 1.0 4.8e-15 56.3 1.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Ank PF00023.30 RJW65955.1 - 3.4e-14 52.6 23.9 0.0011 19.3 0.1 8.4 9 0 0 9 9 9 4 Ankyrin repeat Adeno_E3 PF06040.11 RJW65955.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 protein BPL_LplA_LipB PF03099.19 RJW65956.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CEP63 PF17045.5 RJW65957.1 - 1.9e-07 31.3 40.9 1.9e-07 31.3 40.9 3.8 3 1 1 4 4 4 1 Centrosomal protein of 63 kDa Baculo_LEF5 PF04838.12 RJW65957.1 - 0.016 15.3 4.0 0.023 14.7 2.4 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 DUF2935 PF11155.8 RJW65957.1 - 2.4 8.5 9.4 1.2e+02 3.0 0.0 4.5 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) DUF4407 PF14362.6 RJW65957.1 - 2.9 7.2 31.5 1.6 8.0 8.0 3.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) UQ_con PF00179.26 RJW65958.1 - 1.2e-50 170.8 0.0 1.4e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RJW65958.1 - 0.0012 18.6 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RJW65958.1 - 0.022 15.0 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain Arf PF00025.21 RJW65959.1 - 2.4e-17 63.0 0.0 2.7e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RJW65959.1 - 0.04 13.5 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Ras family 7tm_1 PF00001.21 RJW65960.1 - 0.0065 15.8 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Shisa PF13908.6 RJW65960.1 - 0.024 14.9 6.6 0.024 14.9 6.6 2.3 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Ion_trans PF00520.31 RJW65961.1 - 1.7e-39 135.5 12.7 2.2e-39 135.2 12.7 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RJW65961.1 - 2.7e-23 82.2 0.0 6.8e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RJW65961.1 - 1.9e-12 47.0 6.4 1.9e-12 47.0 6.4 2.9 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 RJW65961.1 - 0.00015 21.8 0.0 0.00083 19.4 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain FGFR3_TM PF18123.1 RJW65961.1 - 0.14 11.7 6.8 0.75 9.4 0.1 2.8 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain PKD_channel PF08016.12 RJW65961.1 - 0.17 10.5 14.1 0.5 9.0 14.1 1.8 1 1 0 1 1 1 0 Polycystin cation channel DUF5326 PF17260.2 RJW65961.1 - 2.1 8.5 5.4 0.4 10.8 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5326) ADK PF00406.22 RJW65962.1 - 3.5e-18 66.1 0.0 5.4e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RJW65962.1 - 7e-10 39.5 0.0 1.4e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RJW65962.1 - 0.00018 21.7 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RJW65962.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 RJW65962.1 - 0.025 14.8 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RJW65962.1 - 0.027 14.6 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Hydin_ADK PF17213.3 RJW65962.1 - 0.028 14.7 0.0 6.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NTPase_1 PF03266.15 RJW65962.1 - 0.036 14.0 0.0 0.38 10.6 0.0 2.3 1 1 1 2 2 2 0 NTPase KTI12 PF08433.10 RJW65962.1 - 0.065 12.7 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 RJW65962.1 - 0.072 13.5 0.0 0.32 11.4 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 RJW65962.1 - 0.11 13.1 0.0 0.33 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain SH2 PF00017.24 RJW65963.1 - 7.1e-11 42.0 0.0 8.1e-10 38.7 0.0 2.5 2 0 0 2 2 2 1 SH2 domain PH PF00169.29 RJW65963.1 - 2.7e-07 31.0 0.0 1.2e-06 29.0 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 RJW65963.1 - 0.017 15.5 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain JmjC PF02373.22 RJW65964.1 - 1.3e-40 138.4 0.1 3.1e-40 137.2 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 RJW65964.1 - 8.2e-12 44.9 0.1 2e-11 43.6 0.1 1.7 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.6 RJW65964.1 - 2.1e-05 24.0 3.0 2.1e-05 24.0 3.0 2.8 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 RJW65964.1 - 0.033 14.1 0.6 0.033 14.1 0.6 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Gal-bind_lectin PF00337.22 RJW65965.1 - 2.4e-10 40.0 0.0 1.6e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 Galactoside-binding lectin p25-alpha PF05517.12 RJW65966.1 - 5.3e-37 127.4 3.1 6.4e-37 127.1 3.1 1.0 1 0 0 1 1 1 1 p25-alpha DNA_pol_B PF00136.21 RJW65968.1 - 3.2e-88 296.4 0.0 4e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_2 PF03175.13 RJW65968.1 - 0.1 11.4 0.0 0.22 10.4 0.0 1.4 1 1 0 1 1 1 0 DNA polymerase type B, organellar and viral zf-C4pol PF14260.6 RJW65968.1 - 0.4 11.2 5.7 0.9 10.0 5.7 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Aa_trans PF01490.18 RJW65970.1 - 1.3e-29 103.2 24.5 1.6e-29 102.8 24.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DNA_pol_delta_4 PF04081.13 RJW65970.1 - 0.32 11.3 2.2 4.1 7.7 0.3 2.8 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 TMEM247 PF15444.6 RJW65970.1 - 3.2 7.7 4.4 1.6 8.7 1.2 2.1 3 0 0 3 3 3 0 Transmembrane protein 247 HNOBA PF07701.14 RJW65971.1 - 2.4e-62 210.3 1.5 6.4e-62 208.9 1.5 1.6 1 1 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 RJW65971.1 - 5.2e-49 166.4 0.0 7.5e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MctB PF11382.8 RJW65971.1 - 0.21 11.2 0.8 0.38 10.4 0.8 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB KIP1 PF07765.12 RJW65971.1 - 5.9 7.1 6.6 1.7 8.8 0.5 3.0 4 0 0 4 4 4 0 KIP1-like protein DNA_pol_B_exo1 PF03104.19 RJW65972.1 - 2.3e-16 59.9 0.0 8.7e-09 35.0 0.0 2.5 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain XAP5 PF04921.14 RJW65973.1 - 1e-90 303.9 2.9 1e-90 303.9 2.9 1.6 2 0 0 2 2 2 1 XAP5, circadian clock regulator RVT_1 PF00078.27 RJW65973.1 - 0.053 13.0 0.0 0.43 10.0 0.0 2.2 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Rootletin PF15035.6 RJW65973.1 - 4.9 7.1 12.5 22 5.0 12.5 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Aldo_ket_red PF00248.21 RJW65974.1 - 2.7e-47 161.4 0.0 4.6e-47 160.6 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Bin3 PF06859.12 RJW65976.1 - 4.9e-30 104.4 0.0 8.4e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 RJW65976.1 - 7e-09 36.3 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW65976.1 - 7.5e-08 32.3 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RJW65976.1 - 4.7e-07 29.8 0.0 8.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RJW65976.1 - 1.5e-06 28.8 0.0 5.4e-06 27.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RJW65976.1 - 5.1e-06 27.1 0.0 8.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RJW65976.1 - 0.00093 18.8 0.0 0.0034 16.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 RJW65976.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase RabGAP-TBC PF00566.18 RJW65977.1 - 1.9e-38 132.3 0.3 1.3e-28 100.1 0.0 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GRAM PF02893.20 RJW65977.1 - 1.3e-09 38.0 0.0 3.2e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_1 PF00036.32 RJW65977.1 - 0.002 17.5 1.1 0.031 13.8 0.1 3.3 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 RJW65977.1 - 0.11 12.3 1.3 0.54 10.2 0.2 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 RJW65977.1 - 0.45 11.0 1.9 1.1 9.7 0.7 2.4 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 RJW65977.1 - 0.48 10.5 2.2 1.4 9.0 0.2 2.8 3 0 0 3 3 3 0 EF-hand domain HALZ PF02183.18 RJW65978.1 - 0.01 16.0 4.4 0.01 16.0 4.4 10.3 10 2 3 13 13 13 0 Homeobox associated leucine zipper KxDL PF10241.9 RJW65978.1 - 0.018 15.3 5.6 0.018 15.3 5.6 7.4 4 2 4 8 8 8 0 Uncharacterized conserved protein GBR2_CC PF18455.1 RJW65978.1 - 2.3 8.4 8.2 6.1 7.1 0.1 4.8 4 1 1 5 5 5 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain LLC1 PF14945.6 RJW65978.1 - 6 7.5 6.6 2.2 8.9 1.5 2.9 2 1 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein PID PF00640.23 RJW65981.1 - 7.3e-12 45.5 0.1 1.2e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 RJW65981.1 - 1.6e-08 34.5 0.0 6.3e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 SH2 domain PID_2 PF14719.6 RJW65981.1 - 0.0071 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) YwqJ-deaminase PF14431.6 RJW65982.1 - 1.2 9.4 3.2 4.9 7.3 0.1 2.5 3 0 0 3 3 3 0 YwqJ-like deaminase zf-3CxxC PF13695.6 RJW65983.1 - 3.7e-28 97.9 1.4 7.6e-28 96.9 1.4 1.5 1 0 0 1 1 1 1 Zinc-binding domain Peptidase_C14 PF00656.22 RJW65983.1 - 0.021 14.8 0.1 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 Caspase domain zf-Dof PF02701.15 RJW65983.1 - 0.081 13.1 0.9 0.66 10.2 0.1 2.5 2 0 0 2 2 2 0 Dof domain, zinc finger EGF PF00008.27 RJW65984.1 - 4.1e-11 43.0 29.2 2.4e-07 30.9 6.0 4.6 3 1 0 3 3 3 3 EGF-like domain EGF_2 PF07974.13 RJW65984.1 - 1.9e-05 24.9 3.1 1.9e-05 24.9 3.1 4.1 4 1 0 4 4 4 2 EGF-like domain hEGF PF12661.7 RJW65984.1 - 6.3e-05 23.5 30.6 0.00038 21.0 5.8 5.2 4 1 0 4 4 4 3 Human growth factor-like EGF cEGF PF12662.7 RJW65984.1 - 0.86 9.6 15.2 0.096 12.6 2.3 3.7 3 0 0 3 3 3 0 Complement Clr-like EGF-like TFIID-31kDa PF02291.15 RJW65985.1 - 5.1e-26 91.1 0.0 3.1e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 RJW65985.1 - 0.038 14.4 0.1 0.1 13.0 0.1 1.7 1 0 0 1 1 1 0 CENP-S protein Homeodomain PF00046.29 RJW65987.1 - 5.4e-22 77.4 5.5 1.2e-21 76.3 5.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW65987.1 - 0.0033 17.3 0.2 0.014 15.2 0.2 2.1 1 0 0 1 1 1 1 Homeobox KN domain Mannosyl_trans PF05007.13 RJW65988.1 - 2.8e-56 191.3 26.6 5.6e-31 108.3 3.6 2.2 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) PIG-U PF06728.13 RJW65988.1 - 2.2e-12 46.8 6.9 2.2e-12 46.8 6.9 2.6 2 2 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 RJW65988.1 - 1.5e-05 24.8 12.6 1.5e-05 24.8 12.6 3.6 3 2 0 3 3 3 1 Glycosyltransferase family 87 PRIMA1 PF16101.5 RJW65988.1 - 0.71 9.9 2.7 1.3 9.1 0.1 2.5 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 PARG_cat PF05028.14 RJW65989.1 - 1.6e-27 96.7 0.0 9.2e-24 84.3 0.0 3.0 2 1 0 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) WW PF00397.26 RJW65990.1 - 1.6e-10 40.9 7.1 3.5e-10 39.8 7.1 1.6 1 0 0 1 1 1 1 WW domain zf-U1 PF06220.12 RJW65990.1 - 1.2e-08 34.6 0.7 2.4e-08 33.6 0.7 1.6 1 0 0 1 1 1 1 U1 zinc finger DUF4633 PF15464.6 RJW65990.1 - 0.044 13.9 0.7 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) IMD PF08397.11 RJW65990.1 - 0.1 12.0 1.7 0.71 9.2 1.2 2.1 2 0 0 2 2 2 0 IRSp53/MIM homology domain DUF3541 PF12060.8 RJW65990.1 - 0.11 12.2 0.3 4.7 6.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) CTU2 PF10288.9 RJW65990.1 - 0.43 10.8 3.7 6 7.2 2.2 2.7 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF5582 PF17819.1 RJW65991.1 - 7.1e-05 23.3 0.3 0.00012 22.6 0.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF5586 PF17824.1 RJW65991.1 - 0.012 14.8 0.1 0.025 13.7 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5586) EF-hand_7 PF13499.6 RJW65991.1 - 0.072 13.5 0.1 0.24 11.9 0.0 2.0 2 2 0 2 2 2 0 EF-hand domain pair AAA PF00004.29 RJW65992.1 - 2.9e-43 147.5 0.0 3.1e-38 131.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW65992.1 - 1e-06 29.3 1.6 0.45 10.9 0.1 4.3 2 2 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 RJW65992.1 - 3.5e-06 26.7 0.0 0.019 14.8 0.0 2.7 3 0 0 3 3 3 2 AAA+ lid domain AAA_22 PF13401.6 RJW65992.1 - 9e-06 26.0 0.0 0.0024 18.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RJW65992.1 - 3.4e-05 23.8 0.1 0.01 15.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RJW65992.1 - 0.00021 21.0 0.0 0.023 14.4 0.0 2.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RJW65992.1 - 0.00087 19.5 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 RJW65992.1 - 0.0063 15.9 0.2 3.1 7.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 RJW65992.1 - 0.01 15.6 0.0 7 6.3 0.0 2.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 RJW65992.1 - 0.011 15.7 0.2 6.7 6.6 0.0 3.1 2 1 0 3 3 3 0 NACHT domain AAA_2 PF07724.14 RJW65992.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 RJW65992.1 - 0.019 15.3 0.0 2.8 8.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 RJW65992.1 - 0.031 14.2 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Pkinase PF00069.25 RJW65993.1 - 9.9e-62 208.7 0.0 1.4e-61 208.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW65993.1 - 1.4e-27 96.6 0.0 2.4e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW65993.1 - 4.5e-05 22.9 0.0 9.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TFIIIC_delta PF12657.7 RJW65993.1 - 4.8e-05 23.4 0.0 9.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term DUF3450 PF11932.8 RJW65993.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PL48 PF15903.5 RJW65995.1 - 2.5e-11 43.2 0.3 2e-07 30.3 0.0 3.5 3 0 0 3 3 3 3 Filopodia upregulated, FAM65 SH2 PF00017.24 RJW65996.1 - 1.5e-25 89.0 0.3 2.8e-25 88.2 0.3 1.5 1 0 0 1 1 1 1 SH2 domain Pkinase_Tyr PF07714.17 RJW65996.1 - 3.9e-11 42.7 0.0 5.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW65996.1 - 1.5e-08 34.3 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 RJW65996.1 - 8.5e-07 28.5 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RJW65996.1 - 7.5e-06 25.7 0.1 1.6e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RJW65996.1 - 0.1 12.3 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain COesterase PF00135.28 RJW65998.1 - 5.2e-85 286.3 0.1 1.4e-58 199.0 0.0 3.2 2 1 1 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 RJW65998.1 - 9.6e-05 22.3 0.1 0.0004 20.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold MRP-S22 PF10245.9 RJW65999.1 - 2.1e-64 217.6 0.0 3.1e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 DSPc PF00782.20 RJW65999.1 - 1.1e-20 73.8 0.0 2e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 RJW65999.1 - 0.0028 18.1 0.0 0.013 15.9 0.0 2.0 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 RJW65999.1 - 0.0032 17.6 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 RJW65999.1 - 0.0081 15.7 0.1 0.02 14.4 0.1 1.6 1 1 1 2 2 2 1 Protein-tyrosine phosphatase DUF442 PF04273.13 RJW65999.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Myosin_tail_1 PF01576.19 RJW66000.1 - 5.6e-15 54.3 21.7 7.5e-15 53.9 21.7 1.1 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 RJW66000.1 - 4.4e-10 39.7 22.6 1.8e-06 27.8 10.2 2.3 1 1 1 2 2 2 2 Intermediate filament protein TTKRSYEDQ PF10212.9 RJW66000.1 - 8.5e-05 21.7 14.8 0.015 14.3 4.5 2.1 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein HOOK PF05622.12 RJW66000.1 - 0.00011 20.5 22.2 0.00024 19.4 22.3 1.5 1 1 0 1 1 1 1 HOOK protein CENP-F_leu_zip PF10473.9 RJW66000.1 - 0.00011 22.2 24.7 0.0027 17.7 10.5 2.3 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HR1 PF02185.16 RJW66000.1 - 0.00026 21.0 15.7 0.0011 19.0 9.6 2.8 2 0 0 2 2 2 1 Hr1 repeat Shugoshin_N PF07558.11 RJW66000.1 - 0.0004 20.2 2.8 0.0016 18.3 0.3 2.9 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Macoilin PF09726.9 RJW66000.1 - 0.0019 16.9 15.1 0.0023 16.6 15.1 1.1 1 0 0 1 1 1 1 Macoilin family CHDCT2 PF08074.11 RJW66000.1 - 0.007 16.6 9.3 0.0082 16.3 8.0 1.8 1 1 0 1 1 1 1 CHDCT2 (NUC038) domain DUF1664 PF07889.12 RJW66000.1 - 0.022 14.8 12.2 0.086 12.9 2.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Yuri_gagarin PF15934.5 RJW66000.1 - 0.023 14.5 11.1 0.039 13.8 11.1 1.4 1 0 0 1 1 1 0 Yuri gagarin TolA_bind_tri PF16331.5 RJW66000.1 - 0.024 14.7 15.4 0.5 10.5 1.1 3.4 1 1 2 3 3 3 0 TolA binding protein trimerisation Spc7 PF08317.11 RJW66000.1 - 0.053 12.4 21.4 0.078 11.9 20.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.13 RJW66000.1 - 0.068 13.6 0.3 0.068 13.6 0.3 2.9 2 1 1 3 3 2 0 Lipoprotein leucine-zipper DUF745 PF05335.13 RJW66000.1 - 0.085 12.6 18.1 0.076 12.7 15.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4200 PF13863.6 RJW66000.1 - 0.27 11.7 24.9 0.19 12.1 19.9 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) KASH_CCD PF14662.6 RJW66000.1 - 0.31 10.8 28.9 0.39 10.5 18.1 3.1 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 RJW66000.1 - 0.33 11.2 31.1 0.074 13.3 26.8 2.1 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) Phage_Mu_Gam PF07352.12 RJW66000.1 - 0.41 10.5 14.9 0.36 10.7 6.7 2.7 1 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Exonuc_VII_L PF02601.15 RJW66000.1 - 0.48 9.9 13.1 0.9 9.0 13.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit CC2-LZ PF16516.5 RJW66000.1 - 0.49 10.8 15.4 0.8 10.1 2.8 2.8 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator IPK PF03770.16 RJW66000.1 - 0.53 10.1 4.8 0.93 9.3 4.8 1.4 1 0 0 1 1 1 0 Inositol polyphosphate kinase Lzipper-MIP1 PF14389.6 RJW66000.1 - 0.62 10.4 18.2 0.36 11.2 2.3 3.6 1 1 3 4 4 3 0 Leucine-zipper of ternary complex factor MIP1 TPR_MLP1_2 PF07926.12 RJW66000.1 - 0.66 10.0 25.9 4.4 7.4 20.5 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 RJW66000.1 - 0.69 10.3 19.5 0.2 12.0 2.2 3.6 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MbeD_MobD PF04899.12 RJW66000.1 - 0.7 10.1 10.4 6.2 7.0 0.6 2.7 1 1 1 2 2 2 0 MbeD/MobD like HAUS-augmin3 PF14932.6 RJW66000.1 - 0.86 9.1 21.3 2.2 7.8 8.0 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Uso1_p115_C PF04871.13 RJW66000.1 - 0.87 10.0 28.6 0.1 13.0 9.7 2.6 2 1 1 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TSNAXIP1_N PF15739.5 RJW66000.1 - 0.95 9.9 17.5 0.071 13.5 8.0 2.4 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF4709 PF15821.5 RJW66000.1 - 1 9.7 12.2 12 6.2 0.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4709) DUF812 PF05667.11 RJW66000.1 - 1 8.1 22.8 0.51 9.2 12.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HemX PF04375.14 RJW66000.1 - 1.1 8.4 16.6 3 7.0 9.2 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Atg14 PF10186.9 RJW66000.1 - 1.2 8.2 14.7 2 7.4 14.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4472 PF14739.6 RJW66000.1 - 1.5 9.6 21.2 3.1 8.6 9.9 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4472) DivIC PF04977.15 RJW66000.1 - 1.7 8.5 21.6 1.3 8.9 7.2 3.7 1 1 3 4 4 4 0 Septum formation initiator CENP-H PF05837.12 RJW66000.1 - 1.8 9.0 25.5 1.5 9.2 9.1 2.8 2 1 1 3 3 2 0 Centromere protein H (CENP-H) Uds1 PF15456.6 RJW66000.1 - 2.1 8.5 23.7 0.025 14.7 13.1 2.7 2 1 1 3 3 3 0 Up-regulated During Septation Prominin PF05478.11 RJW66000.1 - 2.9 5.7 10.8 4.4 5.1 10.8 1.4 1 0 0 1 1 1 0 Prominin FlaC_arch PF05377.11 RJW66000.1 - 3.7 8.0 14.8 0.18 12.2 0.6 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 RJW66000.1 - 4.8 7.4 19.2 1.1 9.4 0.6 3.7 2 1 2 4 4 4 0 bZIP transcription factor UPF0242 PF06785.11 RJW66000.1 - 6.8 6.8 20.1 9.4 6.3 18.7 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 RJW66000.1 - 9.7 6.0 19.4 3.2 7.5 6.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) EF-hand_7 PF13499.6 RJW66001.1 - 1.3e-10 41.5 0.1 3e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW66001.1 - 2e-09 37.2 0.2 2.2e-06 27.4 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW66001.1 - 1.1e-07 30.9 0.4 7.7e-05 22.0 0.0 3.1 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 RJW66001.1 - 1.5e-07 30.8 0.1 2.4e-05 23.9 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 RJW66001.1 - 0.00076 18.9 0.0 0.0018 17.7 0.0 1.7 1 0 0 1 1 1 1 EF hand MnmE_helical PF12631.7 RJW66001.1 - 0.0086 16.3 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 MnmE helical domain Syntaxin-6_N PF09177.11 RJW66001.1 - 0.2 12.2 1.0 0.88 10.2 0.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Ribosomal_L30_N PF08079.12 RJW66002.1 - 2.8e-05 24.3 10.9 6e-05 23.2 10.9 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 RJW66002.1 - 3.5e-05 23.6 0.0 9.3e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PAS_8 PF13188.7 RJW66002.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_7 PF12860.7 RJW66002.1 - 0.047 13.9 0.3 0.48 10.6 0.0 2.5 2 1 1 3 3 3 0 PAS fold Cucumo_2B PF03263.13 RJW66002.1 - 8.6 6.9 6.7 5.8 7.4 2.6 2.3 1 1 1 2 2 2 0 Cucumovirus protein 2B Y_phosphatase PF00102.27 RJW66003.1 - 1.8e-60 204.5 0.1 3.2e-60 203.6 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RJW66003.1 - 0.0072 16.3 0.0 0.044 13.8 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Vma12 PF11712.8 RJW66003.1 - 0.095 12.8 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DSPc PF00782.20 RJW66003.1 - 0.12 12.2 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain C2 PF00168.30 RJW66004.1 - 7.7e-24 84.0 0.0 1.3e-12 47.9 0.0 2.2 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 RJW66004.1 - 6e-05 23.0 0.0 0.052 13.5 0.0 2.3 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 Baculo_11_kDa PF06143.11 RJW66004.1 - 0.0069 15.9 1.3 0.28 10.8 0.7 2.3 2 0 0 2 2 2 1 Baculovirus 11 kDa family DUF1514 PF07438.11 RJW66004.1 - 6.1 6.8 5.7 3.4e+02 1.2 5.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1514) Peptidase_S24 PF00717.23 RJW66005.1 - 2.2e-11 43.6 0.0 2.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like ESSS PF10183.9 RJW66007.1 - 3e-11 43.4 0.0 3.5e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HSP70 PF00012.20 RJW66010.1 - 2.5e-111 372.8 1.3 5.9e-110 368.2 1.3 2.5 1 1 0 1 1 1 1 Hsp70 protein RVT_1 PF00078.27 RJW66010.1 - 2.5e-46 158.0 0.3 7.4e-46 156.4 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MreB_Mbl PF06723.13 RJW66010.1 - 0.00043 19.2 0.0 0.018 13.9 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein GPS PF01825.21 RJW66011.1 - 0.0081 16.7 0.1 0.017 15.6 0.1 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif AAA PF00004.29 RJW66012.1 - 1.1e-11 45.3 0.0 3.2e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 RJW66012.1 - 0.00039 20.0 1.5 0.00078 19.0 0.1 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_16 PF13191.6 RJW66012.1 - 0.035 14.5 0.3 0.22 11.9 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Peptidase_M1 PF01433.20 RJW66014.1 - 0.038 13.6 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain 7tm_1 PF00001.21 RJW66015.1 - 6.2e-41 140.5 3.8 9e-41 139.9 3.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW66015.1 - 3.7e-05 23.5 17.3 0.0003 20.5 13.3 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RJW66015.1 - 0.002 17.9 5.2 0.0031 17.3 5.2 1.2 1 0 0 1 1 1 1 Olfactory receptor NuA4 PF09340.10 RJW66017.1 - 2.7e-21 75.2 0.0 6e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Phage-MuB_C PF09077.11 RJW66017.1 - 0.13 12.2 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Mu B transposition protein, C terminal C2 PF00168.30 RJW66018.1 - 1.6e-19 70.1 0.1 1e-10 41.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 RJW66018.1 - 0.0012 18.8 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF443 PF04276.12 RJW66018.1 - 0.05 13.4 1.2 0.088 12.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF443) LptF_LptG PF03739.14 RJW66018.1 - 0.076 11.9 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Baculo_11_kDa PF06143.11 RJW66018.1 - 0.53 9.9 3.2 1.4 8.6 3.2 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Cas_DxTHG PF09455.10 RJW66019.1 - 0.011 15.3 0.9 0.011 15.3 0.9 1.8 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family FHIPEP PF00771.20 RJW66019.1 - 0.022 13.3 0.7 0.029 12.8 0.7 1.3 1 0 0 1 1 1 0 FHIPEP family Pkinase PF00069.25 RJW66020.1 - 2.1e-43 148.6 0.0 4.9e-40 137.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66020.1 - 2.1e-15 56.7 0.0 6.3e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase AAA_6 PF12774.7 RJW66021.1 - 9.1e-119 396.2 0.0 1.6e-118 395.4 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW66021.1 - 2.1e-98 330.1 0.1 2.1e-98 330.1 0.1 2.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 RJW66021.1 - 4.8e-27 94.8 3.8 2.3e-25 89.3 0.0 3.9 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 RJW66021.1 - 8e-25 87.5 0.0 5.8e-20 71.7 0.0 3.9 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RJW66021.1 - 2.5e-06 28.0 0.6 0.0011 19.4 0.0 3.8 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 RJW66021.1 - 8e-05 23.1 0.6 0.38 11.2 0.0 3.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RJW66021.1 - 0.00011 22.0 0.0 0.049 13.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RJW66021.1 - 0.00012 21.8 0.3 0.077 12.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 RJW66021.1 - 0.00026 21.3 1.3 0.052 13.8 0.0 3.5 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 RJW66021.1 - 0.0016 18.9 1.6 0.0052 17.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 RJW66021.1 - 0.0017 18.9 0.5 0.25 11.9 0.0 3.7 4 0 0 4 4 2 1 AAA domain AAA_23 PF13476.6 RJW66021.1 - 0.0022 18.6 0.1 0.024 15.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 RJW66021.1 - 0.0041 17.1 1.6 0.015 15.2 0.0 2.6 3 0 0 3 3 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 RJW66021.1 - 0.0059 16.5 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 RJW66021.1 - 0.015 15.7 0.0 0.48 10.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 RJW66021.1 - 0.015 15.5 0.0 0.59 10.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 RJW66021.1 - 0.021 14.6 0.0 0.061 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 RJW66021.1 - 0.028 13.6 0.1 0.099 11.8 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 RJW66021.1 - 0.036 13.8 0.0 0.17 11.6 0.0 2.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 RJW66021.1 - 0.08 12.4 0.1 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region IIGP PF05049.13 RJW66021.1 - 0.12 11.5 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) IstB_IS21 PF01695.17 RJW66021.1 - 0.14 11.8 0.3 0.85 9.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 RJW66021.1 - 0.15 11.4 0.0 0.5 9.6 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 RJW66021.1 - 0.31 11.0 2.9 0.77 9.7 0.0 3.2 5 0 0 5 5 4 0 NACHT domain AAA_33 PF13671.6 RJW66021.1 - 0.39 10.9 2.0 1.6 8.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain ZapB PF06005.12 RJW66021.1 - 8.5 6.9 9.8 23 5.5 2.2 4.0 3 0 0 3 3 2 0 Cell division protein ZapB C2 PF00168.30 RJW66025.1 - 6e-26 90.7 0.1 1.8e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 C2 domain LapA_dom PF06305.11 RJW66025.1 - 0.073 12.9 1.1 0.13 12.1 1.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 RJW66025.1 - 0.18 10.6 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PRIMA1 PF16101.5 RJW66025.1 - 3.2 7.8 5.7 6.1 6.9 5.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CBM_21 PF03370.13 RJW66026.1 - 5e-25 87.9 0.1 9.2e-25 87.0 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 RJW66026.1 - 7.6e-10 39.2 0.2 1.9e-09 37.9 0.2 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) PTCB-BRCT PF12738.7 RJW66028.1 - 1.9e-25 88.6 0.0 8.8e-19 67.2 0.0 3.7 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 RJW66028.1 - 2.3e-19 69.5 0.0 2.6e-11 43.7 0.0 4.7 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RJW66028.1 - 1.6e-10 41.3 0.0 0.019 15.4 0.0 5.2 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RJW66028.1 - 0.00082 19.2 0.0 0.0076 16.1 0.0 2.6 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 RJW66028.1 - 0.0019 18.4 0.0 0.85 10.0 0.0 3.3 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 RJW66028.1 - 0.0022 18.0 0.0 0.011 15.7 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RhoGAP PF00620.27 RJW66030.1 - 5.1e-08 32.9 0.0 0.00019 21.3 0.1 2.7 2 1 0 2 2 2 2 RhoGAP domain DUF3318 PF11780.8 RJW66030.1 - 0.054 13.4 0.7 0.55 10.2 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3318) DAD PF02109.16 RJW66031.1 - 4.2e-44 149.3 2.6 4.9e-44 149.1 2.6 1.0 1 0 0 1 1 1 1 DAD family IQ PF00612.27 RJW66032.1 - 1.2e-07 30.9 18.9 2.4e-05 23.7 0.7 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif RasGAP PF00616.19 RJW66032.1 - 7e-07 29.2 0.1 2.4e-05 24.1 0.0 3.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 RJW66032.1 - 2.9e-05 24.2 0.0 8.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 RasGAP C-terminus UPF0203 PF05254.12 RJW66036.1 - 7.9e-16 58.1 0.1 1e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 RJW66036.1 - 0.01 16.2 1.1 0.028 14.8 0.6 1.8 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 RJW66036.1 - 0.066 13.2 1.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 RJW66036.1 - 0.11 12.8 2.6 5 7.5 0.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 RJW66036.1 - 0.11 12.5 1.4 1.5 8.9 1.5 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like 7TM_GPCR_Srbc PF10316.9 RJW66036.1 - 0.26 10.8 0.1 0.35 10.4 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc Bestrophin PF01062.21 RJW66037.1 - 3.7e-67 226.8 7.8 1.1e-34 120.2 1.6 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel RF-1 PF00472.20 RJW66038.1 - 9.5e-05 22.3 0.8 0.00012 22.0 0.8 1.2 1 0 0 1 1 1 1 RF-1 domain DUF2013 PF09431.10 RJW66039.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) Amido_AtzD_TrzD PF09663.10 RJW66040.1 - 0.16 10.9 0.4 0.75 8.8 0.4 1.8 1 1 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) SET PF00856.28 RJW66042.1 - 0.0071 16.8 0.1 0.25 11.7 0.1 2.3 1 1 0 1 1 1 1 SET domain L_HMGIC_fpl PF10242.9 RJW66042.1 - 0.081 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein XendoU PF09412.10 RJW66043.1 - 5.5e-71 238.9 0.0 6.4e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 RJW66043.1 - 0.0099 16.2 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial EndoU nuclease LicD PF04991.13 RJW66044.1 - 5e-06 26.8 0.6 1.1e-05 25.7 0.6 1.5 1 0 0 1 1 1 1 LicD family UBA PF00627.31 RJW66045.1 - 0.17 11.8 0.6 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 UBA/TS-N domain DUF1296 PF06972.11 RJW66045.1 - 0.19 11.9 0.0 0.9 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) hNIFK_binding PF12196.8 RJW66045.1 - 0.26 10.8 0.6 0.52 9.9 0.6 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK FlxA PF14282.6 RJW66045.1 - 1.1 9.3 14.6 0.26 11.3 10.9 1.9 2 0 0 2 2 2 0 FlxA-like protein CFAP91 PF14738.6 RJW66047.1 - 8.1e-55 185.1 10.6 8.1e-55 185.1 10.6 3.3 2 1 0 2 2 2 1 Cilia- and flagella-associated protein 91 CaM-KIIN PF15170.6 RJW66047.1 - 0.052 13.7 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor DENN PF02141.21 RJW66047.1 - 0.23 11.4 1.3 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 DENN (AEX-3) domain DIT1_PvcA PF05141.12 RJW66047.1 - 4.2 6.8 7.0 1.2 8.6 1.4 2.2 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein UPF0203 PF05254.12 RJW66048.1 - 7.9e-16 58.1 0.1 1e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 RJW66048.1 - 0.01 16.2 1.1 0.028 14.8 0.6 1.8 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 RJW66048.1 - 0.066 13.2 1.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 RJW66048.1 - 0.11 12.8 2.6 5 7.5 0.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 RJW66048.1 - 0.11 12.5 1.4 1.5 8.9 1.5 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like 7TM_GPCR_Srbc PF10316.9 RJW66048.1 - 0.26 10.8 0.1 0.35 10.4 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc RVT_1 PF00078.27 RJW66049.1 - 5.3e-15 55.5 0.0 1.7e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rx_N PF18052.1 RJW66049.1 - 0.067 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Rx N-terminal domain TTc_toxin_rep PF18807.1 RJW66051.1 - 7.6 6.4 5.9 12 5.8 1.6 2.7 2 0 0 2 2 2 0 Tripartite Tc toxins repeat Laminin_EGF PF00053.24 RJW66054.1 - 1.7e-58 194.6 135.4 1e-09 38.3 14.7 9.2 6 2 3 9 9 9 8 Laminin EGF domain Laminin_G_2 PF02210.24 RJW66054.1 - 2.8e-09 37.6 0.0 0.027 15.1 0.0 3.8 3 0 0 3 3 3 3 Laminin G domain Laminin_B PF00052.18 RJW66054.1 - 0.012 15.5 0.0 0.059 13.3 0.0 2.2 1 0 0 1 1 1 0 Laminin B (Domain IV) AbiEi_3 PF11459.8 RJW66054.1 - 0.082 12.6 0.7 0.26 11.0 0.7 1.8 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Thioredoxin PF00085.20 RJW66057.1 - 1.4e-59 198.4 0.4 7e-29 99.9 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 RJW66057.1 - 3.9e-39 134.5 1.0 1.3e-28 100.2 0.3 3.8 2 2 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 RJW66057.1 - 3.1e-08 33.1 1.7 3.1e-08 33.1 1.7 1.6 2 1 0 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.6 RJW66057.1 - 3e-07 30.5 0.1 0.021 15.0 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 RJW66057.1 - 1.2e-06 28.4 0.4 0.0026 17.7 0.0 3.1 2 1 1 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.6 RJW66057.1 - 6.9e-06 26.5 0.9 0.017 15.6 0.0 3.7 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RJW66057.1 - 3.2e-05 24.2 0.4 0.56 10.6 0.0 3.7 4 1 0 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 RJW66057.1 - 3.7e-05 23.2 0.0 0.031 13.6 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 RJW66057.1 - 0.00044 20.0 0.5 4.1 7.1 0.0 3.7 4 0 0 4 4 4 2 Redoxin ERp29_N PF07912.13 RJW66057.1 - 0.0038 17.4 1.3 6 7.0 0.1 3.8 4 1 0 4 4 4 2 ERp29, N-terminal domain Omp28 PF11551.8 RJW66057.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein Omp28 Thioredoxin_9 PF14595.6 RJW66057.1 - 0.076 12.8 0.0 7.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin TolA_bind_tri PF16331.5 RJW66059.1 - 0.0078 16.3 2.6 0.0078 16.3 2.6 5.4 6 2 0 6 6 6 1 TolA binding protein trimerisation IFP_35_N PF07334.13 RJW66059.1 - 0.069 13.2 0.4 0.069 13.2 0.4 5.3 5 1 1 6 6 6 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus EzrA PF06160.12 RJW66059.1 - 0.69 8.0 24.3 0.046 11.9 5.7 3.2 3 1 2 5 5 5 0 Septation ring formation regulator, EzrA Cnn_1N PF07989.11 RJW66059.1 - 0.82 9.9 23.4 1.4 9.2 0.3 5.7 5 1 0 5 5 5 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 RJW66059.1 - 6.6 6.9 28.4 0.066 13.3 1.8 6.0 5 1 1 6 6 6 0 bZIP transcription factor Bestrophin PF01062.21 RJW66062.1 - 4.2e-65 220.1 9.0 3e-36 125.3 1.1 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Pkinase PF00069.25 RJW66063.1 - 5e-09 35.9 0.0 7.4e-07 28.8 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66063.1 - 0.00016 21.0 0.0 0.00073 18.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase zf-C2H2 PF00096.26 RJW66065.1 - 1.2e-14 53.9 29.2 0.00029 21.1 1.7 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66065.1 - 4e-12 45.9 22.7 0.019 15.8 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW66065.1 - 2.2e-10 40.5 27.5 2.1e-06 27.9 3.8 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW66065.1 - 3.9e-05 23.8 8.8 0.41 11.0 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RJW66065.1 - 0.019 15.2 16.8 0.16 12.2 3.3 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 RJW66065.1 - 0.54 10.8 7.4 30 5.2 0.1 4.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_9 PF14369.6 RJW66065.1 - 0.68 10.2 12.4 4.3 7.7 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon Zn-ribbon_8 PF09723.10 RJW66065.1 - 0.92 9.7 11.8 0.77 9.9 2.5 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 RJW66065.1 - 1.6 8.4 11.2 15 5.2 0.2 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 RJW66065.1 - 2.5 8.6 12.2 4.2 7.9 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RJW66065.1 - 5.3 7.4 9.2 59 4.1 1.4 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 RJW66065.1 - 7.9 6.6 18.5 3.1 7.9 0.8 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger PP2C PF00481.21 RJW66067.1 - 8.2e-65 219.0 0.0 2.7e-52 178.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C GTP_EFTU PF00009.27 RJW66068.1 - 4.9e-22 78.4 0.0 7.9e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RJW66068.1 - 0.00073 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 RJW66068.1 - 0.0028 18.0 0.0 0.01 16.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 ABC_tran PF00005.27 RJW66068.1 - 0.092 13.3 0.0 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.9 RJW66068.1 - 0.11 12.3 0.1 39 4.0 0.0 3.6 3 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 RJW66068.1 - 0.17 12.0 0.1 1 9.4 0.1 2.2 1 1 1 2 2 2 0 Dynamin family DNA_photolyase PF00875.18 RJW66069.1 - 1.4e-16 60.9 0.4 3.7e-15 56.3 0.2 2.9 2 1 0 2 2 2 1 DNA photolyase CLP1_P PF16575.5 RJW66069.1 - 1.9e-12 47.4 0.0 9.9e-12 45.0 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 RJW66069.1 - 8.6e-11 42.3 0.0 1.7e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 DRIM PF07539.12 RJW66071.1 - 3.9e-166 554.0 14.8 3.9e-166 554.0 14.8 3.7 4 1 0 4 4 4 2 Down-regulated in metastasis HEAT_EZ PF13513.6 RJW66071.1 - 0.095 13.2 0.1 1.2 9.7 0.1 3.1 1 0 0 1 1 1 0 HEAT-like repeat HEAT PF02985.22 RJW66071.1 - 0.84 10.1 3.7 1.5e+02 3.1 0.1 5.6 4 0 0 4 4 4 0 HEAT repeat Dynamitin PF04912.14 RJW66072.1 - 1.2e-98 331.0 24.4 1.5e-98 330.7 24.4 1.1 1 0 0 1 1 1 1 Dynamitin RVT_1 PF00078.27 RJW66072.1 - 3.3e-05 23.5 0.0 7.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Laminin_II PF06009.12 RJW66072.1 - 0.0019 18.2 14.1 0.057 13.4 1.7 4.0 4 1 1 5 5 5 2 Laminin Domain II KCNQ_channel PF03520.14 RJW66072.1 - 0.012 15.5 0.6 1 9.1 0.0 2.5 2 0 0 2 2 2 0 KCNQ voltage-gated potassium channel DUF3470 PF11953.8 RJW66072.1 - 0.1 12.6 0.2 1 9.4 0.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3470) DUF713 PF05218.14 RJW66072.1 - 0.21 11.3 7.9 0.047 13.4 3.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF713) DUF2408 PF10303.9 RJW66072.1 - 0.37 11.3 10.8 0.33 11.5 5.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) SesA PF17107.5 RJW66072.1 - 1.1 9.4 6.7 0.3 11.3 1.3 2.7 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF155 PF02582.14 RJW66072.1 - 1.4 9.0 5.1 1.7 8.7 3.5 1.9 1 1 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 KxDL PF10241.9 RJW66072.1 - 1.5 9.2 6.7 2.2 8.6 0.2 3.8 3 1 0 3 3 3 0 Uncharacterized conserved protein FlaC_arch PF05377.11 RJW66072.1 - 1.5 9.2 11.8 2.7 8.5 0.1 4.8 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Spectrin PF00435.21 RJW66072.1 - 2.5 8.6 10.6 3 8.4 2.8 3.7 2 1 2 4 4 4 0 Spectrin repeat Spc7 PF08317.11 RJW66072.1 - 4.6 6.0 19.6 0.72 8.7 8.3 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein FapA PF03961.13 RJW66072.1 - 6 5.4 5.5 3.3 6.2 1.9 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A IL11 PF07400.11 RJW66072.1 - 6.6 6.3 8.6 4.8 6.8 5.3 2.4 2 1 1 3 3 3 0 Interleukin 11 DUF2203 PF09969.9 RJW66072.1 - 7.4 7.3 8.9 23 5.7 0.3 3.9 3 1 2 5 5 5 0 Uncharacterized conserved protein (DUF2203) BCNT PF07572.12 RJW66074.1 - 6e-22 77.5 0.9 1.5e-21 76.2 0.9 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development DEAD PF00270.29 RJW66076.1 - 1.6e-50 171.3 0.0 2.7e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW66076.1 - 2e-31 108.6 0.0 1.5e-30 105.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW66076.1 - 0.002 18.2 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 RJW66076.1 - 0.25 10.1 0.0 0.61 8.8 0.0 1.6 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ABC_tran PF00005.27 RJW66077.1 - 3.5e-49 166.8 0.0 3.4e-28 98.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RJW66077.1 - 4.6e-28 98.6 11.3 8e-28 97.9 11.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RJW66077.1 - 3.7e-10 39.6 0.1 0.11 11.9 0.0 4.3 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RJW66077.1 - 4e-07 30.1 0.1 0.0032 17.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RJW66077.1 - 1.2e-06 28.6 0.4 0.2 11.5 0.0 3.6 3 1 1 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RJW66077.1 - 2.5e-05 24.7 0.1 0.35 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 RJW66077.1 - 3.8e-05 24.3 1.0 0.15 12.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RJW66077.1 - 4.5e-05 23.7 0.1 0.55 10.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RJW66077.1 - 0.00014 21.8 1.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 RJW66077.1 - 0.0014 18.7 2.4 0.8 9.7 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 RJW66077.1 - 0.0018 18.0 2.0 0.47 10.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RJW66077.1 - 0.0022 17.3 0.1 0.69 9.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 RJW66077.1 - 0.0041 16.3 0.1 0.14 11.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.17 RJW66077.1 - 0.006 16.7 0.5 0.41 10.7 0.3 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 RJW66077.1 - 0.013 14.7 0.5 1.6 7.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 RJW66077.1 - 0.014 15.1 0.0 6.1 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 RJW66077.1 - 0.017 14.6 0.1 7.4 6.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 RJW66077.1 - 0.027 14.7 0.3 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 RJW66077.1 - 0.036 13.8 0.1 1.8 8.3 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RJW66077.1 - 0.043 14.4 0.0 10 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 RJW66077.1 - 0.05 13.8 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RJW66077.1 - 0.055 13.4 0.7 2.7 7.9 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_5 PF07728.14 RJW66077.1 - 0.056 13.4 0.1 16 5.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 RJW66077.1 - 0.059 13.8 0.0 2.9 8.3 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 RJW66077.1 - 0.071 12.2 0.0 6.9 5.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 RJW66077.1 - 0.075 12.6 0.2 11 5.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 RJW66077.1 - 0.12 12.7 0.1 21 5.5 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 RJW66077.1 - 0.14 11.9 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 RJW66077.1 - 0.21 10.6 0.3 0.43 9.6 0.1 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF4064 PF13273.6 RJW66077.1 - 0.88 9.9 4.0 5 7.5 1.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) NDUF_B8 PF05821.11 RJW66078.1 - 8.2e-23 81.2 4.2 1e-22 80.9 4.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) GDP_Man_Dehyd PF16363.5 RJW66079.1 - 1.1e-125 419.5 0.0 1.3e-125 419.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RJW66079.1 - 5.7e-57 193.0 0.0 6.9e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RJW66079.1 - 0.17 10.9 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain STAG PF08514.11 RJW66080.1 - 1.8e-36 124.4 0.4 5.3e-36 123.0 0.4 1.8 1 0 0 1 1 1 1 STAG domain MerR-DNA-bind PF09278.11 RJW66080.1 - 0.53 10.9 3.1 16 6.1 1.4 3.3 2 0 0 2 2 2 0 MerR, DNA binding CS PF04969.16 RJW66082.1 - 1.7e-17 64.2 0.4 3.8e-17 63.1 0.3 1.7 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.6 RJW66082.1 - 1.3e-13 50.7 0.2 3.1e-13 49.5 0.2 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Atrophin-1 PF03154.15 RJW66082.1 - 0.35 9.1 6.6 0.51 8.6 6.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family Kunitz_BPTI PF00014.23 RJW66083.1 - 4.5e-29 100.5 3.3 3.6e-14 52.7 0.2 2.1 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain PAN_1 PF00024.26 RJW66083.1 - 0.57 10.2 7.3 0.12 12.4 1.5 2.5 1 1 1 2 2 2 0 PAN domain NIF PF03031.18 RJW66084.1 - 1.1e-38 132.4 0.0 1.6e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ig_3 PF13927.6 RJW66085.1 - 4.4e-10 40.0 0.1 7e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RJW66085.1 - 7.7e-10 39.0 0.0 9.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RJW66085.1 - 9.4e-10 38.5 0.0 1.9e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RJW66085.1 - 4.9e-07 29.7 0.4 1.2e-05 25.3 0.4 2.2 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 RJW66085.1 - 0.0028 17.8 0.1 0.29 11.3 0.0 2.1 1 1 1 2 2 2 2 Immunoglobulin V-set domain V-set_CD47 PF08204.11 RJW66085.1 - 0.06 13.3 1.2 0.6 10.1 0.2 2.0 1 1 1 2 2 2 0 CD47 immunoglobulin-like domain Kunitz_BPTI PF00014.23 RJW66087.1 - 3.2e-33 113.7 24.5 1.9e-11 44.0 2.2 3.3 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain Peptidase_C1 PF00112.23 RJW66088.1 - 1.6e-61 208.2 1.6 2e-61 207.9 1.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RJW66088.1 - 0.00076 18.4 1.4 0.025 13.3 0.3 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 RJW66090.1 - 1.2e-63 215.1 0.8 1.5e-63 214.8 0.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RJW66090.1 - 0.0021 16.9 1.9 0.28 9.9 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Ldl_recept_a PF00057.18 RJW66091.1 - 3.8e-127 414.2 201.5 9e-13 48.2 7.4 13.5 13 0 0 13 13 13 13 Low-density lipoprotein receptor domain class A Ig_2 PF13895.6 RJW66091.1 - 3.2e-23 81.8 4.0 5.5e-06 26.6 0.0 7.9 8 0 0 8 8 8 5 Immunoglobulin domain Ig_3 PF13927.6 RJW66091.1 - 2.9e-20 72.6 5.1 1.5e-05 25.5 0.0 8.0 8 1 1 9 9 9 4 Immunoglobulin domain ig PF00047.25 RJW66091.1 - 8.4e-10 38.7 0.0 0.59 10.3 0.0 7.2 6 2 0 6 6 6 2 Immunoglobulin domain V-set PF07686.17 RJW66091.1 - 3.6e-09 36.7 0.2 0.5 10.5 0.0 7.0 6 1 1 7 7 7 1 Immunoglobulin V-set domain I-set PF07679.16 RJW66091.1 - 8.1e-09 35.4 0.0 0.026 14.6 0.0 6.3 6 1 0 6 6 6 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 RJW66091.1 - 0.0017 18.3 0.0 0.77 9.9 0.0 3.6 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain C2-set PF05790.15 RJW66091.1 - 0.0032 17.6 0.0 1.8 8.8 0.0 4.1 5 0 0 5 5 5 1 Immunoglobulin C2-set domain Ig_6 PF18452.1 RJW66091.1 - 0.012 15.1 0.0 2.3 7.9 0.0 3.4 4 0 0 4 4 4 0 Immunoglobulin domain Iwr1 PF08574.10 RJW66092.1 - 1.3e-12 48.5 10.9 1.3e-12 48.5 10.9 2.3 2 0 0 2 2 2 1 Transcription factor Iwr1 SDA1 PF05285.12 RJW66092.1 - 2.2 7.6 14.5 3.1 7.1 14.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RJW66092.1 - 3.2 5.8 10.8 3.9 5.6 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family SRP9-21 PF05486.12 RJW66093.1 - 1.3e-12 47.9 0.2 6.2e-11 42.5 0.2 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Actin_micro PF17003.5 RJW66093.1 - 0.013 14.8 1.8 0.014 14.6 1.8 1.0 1 0 0 1 1 1 0 Putative actin-like family Zf_RING PF16744.5 RJW66093.1 - 0.079 13.1 0.1 0.095 12.8 0.1 1.2 1 0 0 1 1 1 0 KIAA1045 RING finger RVT_1 PF00078.27 RJW66094.1 - 1.9e-28 99.5 0.0 2.3e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pcc1 PF09341.10 RJW66097.1 - 9.1e-12 44.9 0.2 1.1e-11 44.6 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 zf-Tim10_DDP PF02953.15 RJW66098.1 - 1.4e-24 85.5 0.7 1.9e-24 85.1 0.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TIL PF01826.17 RJW66098.1 - 0.018 15.3 0.5 0.027 14.7 0.5 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Catalase-rel PF06628.12 RJW66098.1 - 0.021 15.0 0.1 3.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Catalase-related immune-responsive NES_C_h PF18208.1 RJW66098.1 - 0.057 13.7 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain B277 PF17623.2 RJW66099.1 - 0.31 10.1 2.8 0.65 9.0 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function Lectin_N PF03954.14 RJW66099.1 - 3.1 7.6 13.0 0.76 9.5 1.8 3.1 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Bacillus_HBL PF05791.11 RJW66099.1 - 3.2 7.6 13.9 2.9 7.7 0.2 3.2 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Kunitz_BPTI PF00014.23 RJW66100.1 - 9.3e-12 45.0 0.1 1.5e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain C2-C2_1 PF11618.8 RJW66102.1 - 3.7e-34 117.8 0.0 1.1e-28 100.0 0.0 3.4 2 1 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 RPGR1_C PF18111.1 RJW66102.1 - 1.2e-13 51.2 0.4 1.7e-12 47.6 0.1 2.9 2 0 0 2 2 2 1 Retinitis pigmentosa G-protein regulator interacting C-terminal C2 PF00168.30 RJW66102.1 - 4.9e-05 23.6 0.1 0.00055 20.2 0.0 2.4 2 0 0 2 2 2 1 C2 domain DUF4777 PF16007.5 RJW66102.1 - 0.072 13.4 0.3 0.19 12.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Vps52 PF04129.12 RJW66103.1 - 3.3e-46 158.1 0.0 8.7e-37 127.0 0.0 2.4 2 1 0 2 2 2 2 Vps52 / Sac2 family Exo70 PF03081.15 RJW66103.1 - 0.053 12.6 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 Exo70 exocyst complex subunit Med7 PF05983.11 RJW66103.1 - 0.083 13.0 1.6 0.087 12.9 0.2 1.7 2 0 0 2 2 2 0 MED7 protein BBS1 PF14779.6 RJW66106.1 - 1.7e-83 280.0 0.0 4.3e-83 278.7 0.0 1.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 RJW66106.1 - 0.12 12.4 0.0 0.94 9.5 0.0 2.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Vps52 PF04129.12 RJW66108.1 - 1e-44 153.2 6.7 1.2e-44 153.0 6.7 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family OSK PF17182.4 RJW66108.1 - 0.0051 16.1 0.6 0.0067 15.7 0.6 1.2 1 0 0 1 1 1 1 OSK domain EGF PF00008.27 RJW66110.1 - 7.9e-19 67.6 71.2 1.6e-08 34.7 9.0 6.0 5 0 0 5 5 5 5 EGF-like domain EGF_2 PF07974.13 RJW66110.1 - 1.4e-10 41.4 86.9 0.0017 18.7 10.0 5.9 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 RJW66110.1 - 1.7e-08 34.8 69.4 2.2e-05 24.9 5.0 7.5 7 0 0 7 7 7 5 Human growth factor-like EGF EGF_CA PF07645.15 RJW66110.1 - 0.0029 17.8 9.0 0.0029 17.8 9.0 6.4 3 3 3 6 6 6 2 Calcium-binding EGF domain zf-MYND PF01753.18 RJW66111.1 - 6.9e-10 38.9 4.0 1.7e-09 37.6 4.0 1.7 1 0 0 1 1 1 1 MYND finger TPR_8 PF13181.6 RJW66111.1 - 0.00018 21.4 2.8 0.27 11.6 0.5 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RJW66111.1 - 0.0011 18.7 1.0 0.1 12.4 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW66111.1 - 0.0018 18.5 8.5 0.28 11.5 1.4 3.8 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW66111.1 - 0.0058 16.7 7.7 0.055 13.6 0.4 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 RJW66111.1 - 0.047 14.3 2.0 6.1 7.8 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 RJW66111.1 - 0.12 12.8 1.3 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-Mss51 PF13824.6 RJW66111.1 - 0.39 10.9 5.4 6.8 6.9 5.4 2.6 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_16 PF13432.6 RJW66111.1 - 3.6 8.3 7.7 1.6 9.4 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Parvo_NS1 PF01057.17 RJW66114.1 - 1.3e-14 54.0 0.0 2.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 RJW66114.1 - 1.2e-11 44.2 0.1 1.7e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Papillomavirus helicase AAA_14 PF13173.6 RJW66114.1 - 0.004 17.2 0.0 0.38 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 RJW66114.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1778 PF08681.11 RJW66114.1 - 0.052 13.5 0.2 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) TsaE PF02367.17 RJW66114.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF1676 PF07898.13 RJW66115.1 - 0.0049 16.9 4.7 0.006 16.6 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) EnY2 PF10163.9 RJW66117.1 - 7.5e-31 106.3 0.1 1.5e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Transcription factor e(y)2 Exo_endo_phos PF03372.23 RJW66117.1 - 0.0036 16.8 0.7 0.0064 16.0 0.7 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RMI1_N PF08585.12 RJW66118.1 - 7.4e-17 61.8 0.1 1.2e-14 54.6 0.1 2.3 1 1 1 2 2 2 2 RecQ mediated genome instability protein Peptidase_S51 PF03575.17 RJW66118.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 ANAPC4_WD40 PF12894.7 RJW66120.1 - 0.0074 16.6 0.0 25 5.2 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain CompInhib_SCIN PF11546.8 RJW66123.1 - 0.023 14.7 0.1 0.054 13.5 0.1 1.6 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN RVT_1 PF00078.27 RJW66125.1 - 1.2e-11 44.5 0.0 1.6e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp PF00026.23 RJW66126.1 - 1.6e-116 389.1 0.3 2e-116 388.8 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW66126.1 - 1.5e-15 57.9 0.5 1.9e-13 51.0 0.5 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RJW66126.1 - 8.5e-06 25.6 0.0 2.6e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RJW66126.1 - 0.005 17.4 0.9 8 7.2 0.2 3.5 2 1 0 2 2 2 1 Aspartyl protease Rogdi_lz PF10259.9 RJW66126.1 - 0.022 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein gag-asp_proteas PF13975.6 RJW66126.1 - 0.03 14.9 0.0 6.2 7.5 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF2046 PF09755.9 RJW66127.1 - 3.7e-107 358.1 52.4 3.4e-84 282.7 36.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) HALZ PF02183.18 RJW66127.1 - 0.0076 16.5 0.5 0.0076 16.5 0.5 5.8 6 1 1 7 7 7 2 Homeobox associated leucine zipper ZapB PF06005.12 RJW66127.1 - 0.012 16.0 8.1 0.012 16.0 8.1 5.4 4 2 1 5 5 5 0 Cell division protein ZapB DASH_Dad4 PF08650.10 RJW66127.1 - 2.9 7.9 12.6 0.14 12.1 0.4 3.6 3 0 0 3 3 3 0 DASH complex subunit Dad4 NCD2 PF04905.13 RJW66130.1 - 2.5e-20 72.7 0.6 2.9e-10 40.2 0.2 2.9 2 0 0 2 2 2 2 NAB conserved region 2 (NCD2) LRR_8 PF13855.6 RJW66130.1 - 4.7e-07 29.5 0.9 1.3e-06 28.1 0.9 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RJW66130.1 - 1.1e-05 25.6 10.2 0.00034 20.9 4.6 2.6 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) WD40 PF00400.32 RJW66130.1 - 0.00064 20.5 0.1 0.075 13.9 0.0 3.3 2 0 0 2 2 2 1 WD domain, G-beta repeat LRR_6 PF13516.6 RJW66130.1 - 0.16 12.1 2.7 28 5.1 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 RJW66130.1 - 0.18 12.5 9.1 3.7 8.5 0.8 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat RVT_1 PF00078.27 RJW66131.1 - 3.8e-24 85.4 0.0 6.6e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 RJW66132.1 - 2.7e-66 223.6 0.0 4.7e-66 222.8 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Nup84_Nup100 PF04121.13 RJW66133.1 - 1.6e-117 393.6 6.4 1.2e-65 222.0 0.0 2.1 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 WD40 PF00400.32 RJW66135.1 - 5.2e-34 115.7 37.9 3.7e-06 27.6 0.2 8.7 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 RJW66135.1 - 4.7e-11 42.4 4.4 1.2e-10 41.1 4.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RJW66135.1 - 3.2e-08 33.2 2.4 1.3e-07 31.3 2.4 2.1 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 RJW66135.1 - 1.6e-05 25.1 0.2 1 9.7 0.1 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW66135.1 - 9.9e-05 21.2 11.5 1.1 7.8 0.1 5.7 1 1 5 6 6 6 4 Nucleoporin Nup120/160 zinc_ribbon_6 PF14599.6 RJW66136.1 - 0.071 13.1 0.8 0.16 12.0 0.3 1.9 2 0 0 2 2 2 0 Zinc-ribbon zf-C2H2 PF00096.26 RJW66136.1 - 0.12 12.9 0.1 0.23 12.0 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type BTB PF00651.31 RJW66138.1 - 1.2e-12 48.0 0.6 7.4e-12 45.5 0.2 2.3 2 0 0 2 2 2 1 BTB/POZ domain Pho86 PF11124.8 RJW66138.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 WD40 PF00400.32 RJW66139.1 - 2.5e-19 69.3 13.2 0.00015 22.5 0.6 8.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW66139.1 - 2.9e-06 27.5 0.0 0.7 10.2 0.0 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW66139.1 - 0.0093 15.9 0.0 3.5 7.4 0.0 3.5 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 RJW66139.1 - 0.15 11.0 0.0 0.61 9.1 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region Sina PF03145.16 RJW66140.1 - 5.3e-82 274.6 0.1 8.5e-82 273.9 0.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_3 PF13920.6 RJW66140.1 - 5.8e-05 22.9 6.5 5.8e-05 22.9 6.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RJW66140.1 - 0.015 15.4 7.2 0.055 13.6 7.2 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RJW66140.1 - 0.057 13.3 10.5 1.3 8.9 11.3 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RJW66140.1 - 0.15 12.0 13.4 0.096 12.5 10.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW66140.1 - 1.8 8.6 15.4 2 8.4 12.2 2.6 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_14 PF17978.1 RJW66140.1 - 3 8.3 6.1 11 6.6 4.8 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Ion_trans PF00520.31 RJW66141.1 - 2.4e-171 567.3 71.7 4.2e-59 199.7 15.0 4.5 5 0 0 5 5 5 4 Ion transport protein Ca_chan_IQ PF08763.11 RJW66141.1 - 4.3e-30 103.7 0.0 1e-29 102.5 0.0 1.7 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 RJW66141.1 - 3.5e-27 93.9 0.1 1.5e-26 91.9 0.0 2.1 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 RJW66141.1 - 0.0022 16.8 6.9 0.0022 16.8 6.9 7.2 6 1 1 7 7 7 5 Polycystin cation channel UBD PF16455.5 RJW66142.1 - 2.2e-37 127.5 0.0 3.6e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 RJW66142.1 - 5.1e-05 22.9 0.0 0.00011 21.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Neisseria_TspB PF05616.13 RJW66142.1 - 0.15 10.5 1.4 0.21 10.1 1.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein LIM PF00412.22 RJW66143.1 - 1.3e-23 82.9 47.1 1.5e-06 28.3 7.7 4.4 4 0 0 4 4 4 4 LIM domain NADH_4Fe-4S PF10589.9 RJW66143.1 - 4.7 7.3 13.7 0.077 13.1 0.9 3.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region LIM PF00412.22 RJW66144.1 - 4.4e-33 113.3 61.9 1.7e-09 37.8 7.5 5.4 5 0 0 5 5 5 5 LIM domain DUF4743 PF15916.5 RJW66147.1 - 7.2e-35 119.6 0.0 1.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 RJW66147.1 - 1.1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RhoGAP PF00620.27 RJW66149.1 - 3.2e-22 79.0 0.2 2.8e-18 66.2 0.3 2.4 2 0 0 2 2 2 2 RhoGAP domain MyTH4 PF00784.17 RJW66149.1 - 5.5e-18 65.4 0.0 5.4e-17 62.2 0.0 2.4 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.26 RJW66149.1 - 0.18 11.9 4.5 0.45 10.6 4.5 1.7 1 0 0 1 1 1 0 WW domain LIM PF00412.22 RJW66150.1 - 1.3e-42 143.9 58.4 7.5e-12 45.3 2.9 5.3 5 0 0 5 5 5 5 LIM domain DUF2175 PF09943.9 RJW66150.1 - 0.099 12.9 0.2 0.099 12.9 0.2 4.3 5 0 0 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2175) LIM PF00412.22 RJW66151.1 - 5e-71 234.8 98.4 1.3e-11 44.5 2.5 8.4 8 0 0 8 8 8 8 LIM domain Rad50_zn_hook PF04423.14 RJW66151.1 - 0.082 12.8 2.2 8.2 6.3 0.0 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF4476 PF14771.6 RJW66151.1 - 0.43 10.9 4.6 7.1 7.0 0.1 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4476) zf-ACC PF17848.1 RJW66151.1 - 2.3 8.4 12.2 9.6 6.4 0.3 5.3 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain LIM PF00412.22 RJW66152.1 - 5.4e-13 49.0 3.3 9.3e-13 48.2 3.3 1.4 1 0 0 1 1 1 1 LIM domain DiS_P_DiS PF06750.13 RJW66152.1 - 0.2 11.8 0.9 0.35 11.0 0.9 1.3 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Kinesin PF00225.23 RJW66153.1 - 5.1e-84 282.0 1.0 6e-84 281.8 0.1 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW66153.1 - 3.7e-40 137.3 0.0 1e-39 135.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding DUF445 PF04286.12 RJW66153.1 - 5.4 6.7 15.1 0.18 11.6 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF445) Metallophos PF00149.28 RJW66155.1 - 7.9e-28 98.3 0.0 1.4e-27 97.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 RJW66155.1 - 3.5e-16 57.5 0.1 1.8e-06 27.0 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RJW66155.1 - 1.9e-13 50.7 1.8 7.4e-06 26.3 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW66155.1 - 3e-13 48.5 0.0 5.6e-05 22.7 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 RJW66155.1 - 5.9e-12 44.5 1.6 9.8e-06 24.8 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RJW66155.1 - 8.5e-10 38.3 0.7 0.0015 18.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair PPP5 PF08321.12 RJW66155.1 - 0.0011 19.3 0.0 0.004 17.4 0.0 2.1 1 0 0 1 1 1 1 PPP5 TPR repeat region IQ PF00612.27 RJW66155.1 - 0.0023 17.6 1.5 0.0075 16.0 1.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_4 PF12763.7 RJW66155.1 - 0.0083 16.1 0.9 1.3 9.0 0.2 3.2 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RJW66155.1 - 0.16 12.3 0.2 0.83 10.0 0.0 2.2 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Gly_transf_sug PF04488.15 RJW66155.1 - 0.19 12.4 0.4 5.4 7.7 0.0 3.2 3 0 0 3 3 3 0 Glycosyltransferase sugar-binding region containing DXD motif Clat_adaptor_s PF01217.20 RJW66156.1 - 7.1e-44 149.2 1.5 1e-43 148.7 1.5 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NDUFA12 PF05071.16 RJW66157.1 - 5.6e-08 33.5 0.6 1.4e-07 32.2 0.6 1.7 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DEAD PF00270.29 RJW66158.1 - 7.3e-42 143.1 0.5 1.1e-41 142.5 0.5 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW66158.1 - 3.3e-28 98.2 0.9 1.2e-27 96.4 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 RJW66158.1 - 0.0026 17.0 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 RJW66158.1 - 0.0057 16.0 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SwrA PF17423.2 RJW66158.1 - 0.087 12.8 0.6 0.21 11.6 0.6 1.7 1 0 0 1 1 1 0 Swarming motility protein TruD PF01142.18 RJW66162.1 - 1.1e-63 215.5 0.0 2.8e-62 210.9 0.0 2.7 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) RRM_1 PF00076.22 RJW66163.1 - 1.2e-15 57.0 0.0 1.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RJW66164.1 - 1.8e-19 69.3 0.0 2.5e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW66164.1 - 0.19 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SART-1 PF03343.13 RJW66165.1 - 1.3e-130 436.9 33.9 1.3e-130 436.9 33.9 1.7 2 0 0 2 2 2 1 SART-1 family NUP50 PF08911.11 RJW66169.1 - 5.5e-14 52.6 0.5 1.3e-13 51.4 0.5 1.7 1 0 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 RJW66169.1 - 6.4e-10 39.4 0.0 3e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 RanBP1 domain MFS_1 PF07690.16 RJW66174.1 - 3.5e-36 124.9 38.3 3.8e-33 114.9 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Galactosyl_T PF01762.21 RJW66175.1 - 0.00038 20.3 0.0 0.00055 19.8 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Prok-JAB PF14464.6 RJW66175.1 - 0.16 11.8 0.8 0.3 10.9 0.5 1.8 2 1 0 2 2 2 0 Prokaryotic homologs of the JAB domain Ribonuclease_3 PF00636.26 RJW66176.1 - 3.2e-40 137.0 0.2 7.2e-21 74.8 0.1 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 RJW66176.1 - 1.3e-33 115.9 0.7 4.3e-16 59.2 0.0 4.4 3 1 0 4 4 4 4 Ribonuclease-III-like RVT_1 PF00078.27 RJW66176.1 - 2.4e-13 50.1 0.0 4.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) dsrm PF00035.26 RJW66176.1 - 8e-11 42.5 0.1 1.8e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cnn_1N PF07989.11 RJW66177.1 - 1.3e-05 25.2 1.8 1.3e-05 25.2 1.8 10.7 6 6 5 11 11 10 1 Centrosomin N-terminal motif 1 Spc7 PF08317.11 RJW66177.1 - 0.00021 20.3 107.9 0.0038 16.1 7.9 7.1 4 2 3 7 7 7 4 Spc7 kinetochore protein EcsC PF12787.7 RJW66177.1 - 0.00025 20.8 0.0 1 9.0 2.0 3.3 2 1 0 2 2 2 2 EcsC protein family CENP-F_leu_zip PF10473.9 RJW66177.1 - 0.00027 21.0 121.2 0.02 14.9 11.1 8.9 4 2 4 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4763 PF15960.5 RJW66177.1 - 0.00049 19.5 4.8 0.00049 19.5 4.8 7.3 5 2 1 7 7 7 2 Domain of unknown function (DUF4763) AAA_13 PF13166.6 RJW66177.1 - 0.0029 16.3 5.5 0.0029 16.3 5.5 5.5 4 2 1 5 5 5 2 AAA domain FapA PF03961.13 RJW66177.1 - 0.0042 15.8 2.4 0.0042 15.8 2.4 6.5 4 3 1 6 6 6 3 Flagellar Assembly Protein A DUF2968 PF11180.8 RJW66177.1 - 0.0048 16.6 6.8 0.0048 16.6 6.8 7.1 5 2 2 7 7 7 1 Protein of unknown function (DUF2968) Nsp1_C PF05064.13 RJW66177.1 - 0.035 13.9 0.3 0.035 13.9 0.3 8.8 8 1 2 10 10 10 0 Nsp1-like C-terminal region DUF948 PF06103.11 RJW66177.1 - 0.039 14.2 34.9 0.7 10.2 0.3 7.0 7 1 1 8 8 8 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 RJW66177.1 - 0.18 11.8 60.7 0.4 10.7 0.0 8.9 6 2 3 9 9 9 0 Protein of unknown function (DUF1664) Sec23_trunk PF04811.15 RJW66177.1 - 1.7 8.2 5.5 0.35 10.4 0.8 2.2 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain GAS PF13851.6 RJW66177.1 - 4.1 6.7 106.6 0.074 12.4 7.3 7.9 4 2 4 9 9 9 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 RJW66177.1 - 8 6.9 100.6 0.22 12.0 6.3 7.4 2 2 5 7 7 7 0 Fez1 Pkinase PF00069.25 RJW66178.1 - 2.1e-37 128.9 0.0 3.1e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66178.1 - 5e-16 58.8 0.0 8.4e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW66178.1 - 0.018 15.0 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW66178.1 - 0.029 13.3 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DJ-1_PfpI PF01965.24 RJW66179.1 - 6.6e-47 159.4 0.4 7.5e-47 159.2 0.4 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 RJW66179.1 - 0.083 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DcpS_C PF11969.8 RJW66180.1 - 2.1e-05 24.9 2.7 3.6e-05 24.2 2.7 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Jnk-SapK_ap_N PF09744.9 RJW66181.1 - 0.011 15.9 17.1 0.41 10.9 3.5 2.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Baculo_PEP_C PF04513.12 RJW66181.1 - 0.24 11.4 11.8 0.51 10.4 7.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fur_reg_FbpB PF13040.6 RJW66181.1 - 0.34 10.5 4.4 0.15 11.6 0.5 2.5 2 1 0 2 2 2 0 Fur-regulated basic protein B Exonuc_VII_L PF02601.15 RJW66181.1 - 0.67 9.5 8.5 0.89 9.1 8.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit BORCS7 PF16088.5 RJW66181.1 - 1.3 9.3 11.6 0.66 10.3 8.1 2.2 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 LMBR1 PF04791.16 RJW66181.1 - 2.3 7.0 8.6 2.7 6.8 8.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF745 PF05335.13 RJW66181.1 - 2.8 7.6 12.3 0.17 11.6 3.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 RJW66181.1 - 3.6 7.6 9.7 1 9.4 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RasGAP_C PF03836.15 RJW66181.1 - 9.6 6.4 14.8 12 6.0 9.6 2.4 1 1 1 2 2 2 0 RasGAP C-terminus 7TM_GPCR_Srw PF10324.9 RJW66183.1 - 0.063 12.6 10.4 0.72 9.1 0.1 3.1 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DEAD PF00270.29 RJW66184.1 - 1.1e-47 162.1 0.0 2.5e-47 160.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW66184.1 - 2.8e-29 101.7 0.1 8.8e-29 100.1 0.3 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW66184.1 - 0.0022 18.0 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ubiquitin PF00240.23 RJW66185.1 - 0.00054 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 RJW66185.1 - 0.16 12.5 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain ODAPH PF15848.5 RJW66187.1 - 0.028 14.9 0.3 0.037 14.5 0.3 1.3 1 1 0 1 1 1 0 Odontogenesis associated phosphoprotein TMEM100 PF16311.5 RJW66192.1 - 0.34 10.5 1.8 0.4 10.3 0.1 1.8 2 0 0 2 2 2 0 Transmembrane protein 100 RT_RNaseH_2 PF17919.1 RJW66194.1 - 3.2e-13 49.6 0.0 3.9e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW66194.1 - 1.3e-09 38.3 0.0 1.6e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase UPF0261 PF06792.11 RJW66194.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) RT_RNaseH_2 PF17919.1 RJW66195.1 - 2.7e-13 49.8 0.0 8.8e-13 48.2 0.0 1.7 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW66195.1 - 3.2e-09 37.0 0.0 7e-09 35.9 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF3701 PF12482.8 RJW66196.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Phage integrase protein SCAN PF02023.17 RJW66196.1 - 0.17 11.7 0.4 0.35 10.7 0.2 1.6 2 0 0 2 2 2 0 SCAN domain Integrase_H2C2 PF17921.1 RJW66197.1 - 2.8e-11 43.4 0.2 9e-11 41.7 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RJW66197.1 - 0.00022 21.4 0.4 0.016 15.4 0.1 2.6 2 0 0 2 2 2 2 H2C2 zinc finger RabGAP-TBC PF00566.18 RJW66198.1 - 3.7e-47 160.8 0.4 3.7e-47 160.8 0.4 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 RJW66198.1 - 1e-13 52.2 0.0 2.6e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein Mod_r PF07200.13 RJW66198.1 - 0.0037 17.4 9.6 0.011 15.9 9.6 1.7 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 RJW66198.1 - 0.012 16.3 11.4 0.048 14.3 6.1 2.6 1 1 1 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 RJW66198.1 - 0.015 15.3 11.1 0.034 14.2 11.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_11 PF13086.6 RJW66198.1 - 0.028 14.2 2.3 0.053 13.3 2.3 1.3 1 0 0 1 1 1 0 AAA domain Not3 PF04065.15 RJW66198.1 - 0.039 13.4 4.5 0.071 12.5 4.5 1.4 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component GBP_C PF02841.14 RJW66198.1 - 0.059 12.8 11.6 0.094 12.1 11.6 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Filament PF00038.21 RJW66198.1 - 0.084 12.4 9.3 0.17 11.4 9.3 1.5 1 0 0 1 1 1 0 Intermediate filament protein Gp-FAR-1 PF05823.12 RJW66198.1 - 0.098 13.0 3.3 0.18 12.1 1.1 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TMF_TATA_bd PF12325.8 RJW66198.1 - 0.11 12.8 9.2 0.24 11.6 9.2 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF5398 PF17376.2 RJW66198.1 - 0.22 12.2 0.5 0.48 11.1 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5398) Spc7 PF08317.11 RJW66198.1 - 0.63 8.9 10.1 0.52 9.1 8.4 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.13 RJW66198.1 - 0.64 10.5 2.9 28 5.2 0.1 3.0 1 1 1 3 3 3 0 Lipoprotein leucine-zipper Fez1 PF06818.15 RJW66198.1 - 0.66 10.4 10.1 1.4 9.4 10.1 1.5 1 0 0 1 1 1 0 Fez1 GvpL_GvpF PF06386.11 RJW66198.1 - 0.68 9.8 4.8 1.3 8.9 4.8 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ATG16 PF08614.11 RJW66198.1 - 0.76 10.0 17.4 0.45 10.7 12.4 2.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) FlxA PF14282.6 RJW66198.1 - 1 9.4 11.4 8 6.5 0.1 2.5 1 1 1 2 2 2 0 FlxA-like protein V_ATPase_I PF01496.19 RJW66198.1 - 1.7 6.5 5.8 2.5 5.9 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 RJW66198.1 - 3.3 7.0 7.9 6.4 6.0 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 RJW66198.1 - 3.9 7.5 5.5 6.9 6.7 4.9 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 RJW66198.1 - 5.1 7.2 16.0 0.12 12.4 1.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 RJW66198.1 - 8.8 6.1 10.4 2.2 8.1 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 RJW66200.1 - 6.2e-05 22.6 12.2 6.2e-05 22.6 12.2 8.9 8 1 1 9 9 9 3 Golgin subfamily A member 5 DUF4508 PF14969.6 RJW66200.1 - 0.0018 18.5 2.0 0.01 16.1 0.5 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4508) NRN1 PF15056.6 RJW66200.1 - 0.35 11.0 5.1 0.44 10.7 1.2 3.1 2 0 0 2 2 2 0 Neuritin protein family Kinesin_assoc PF16183.5 RJW66200.1 - 0.37 10.9 0.0 0.37 10.9 0.0 5.8 5 2 0 6 6 6 0 Kinesin-associated Spectrin_like PF18373.1 RJW66200.1 - 0.63 10.2 6.0 9.1 6.4 0.1 4.5 3 0 0 3 3 3 0 Spectrin like domain MobC PF05713.11 RJW66200.1 - 1.6 9.3 5.8 11 6.5 0.1 4.8 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) Trans_reg_C PF00486.28 RJW66200.1 - 8.1 6.6 6.6 63 3.8 0.1 4.9 4 1 1 5 5 5 0 Transcriptional regulatory protein, C terminal E1_DerP2_DerF2 PF02221.15 RJW66202.1 - 2.8e-16 60.1 0.1 3.2e-16 60.0 0.1 1.0 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 RJW66203.1 - 1.1e-16 61.4 0.2 1.3e-16 61.2 0.2 1.0 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 RJW66205.1 - 3.3e-15 56.7 0.0 7.2e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 ML domain CUB PF00431.20 RJW66206.1 - 2e-22 79.6 0.0 5.8e-22 78.1 0.0 1.8 2 0 0 2 2 2 1 CUB domain E1_DerP2_DerF2 PF02221.15 RJW66208.1 - 8.8e-20 71.5 0.2 3.1e-12 47.1 0.0 2.1 1 1 1 2 2 2 2 ML domain DUF1196 PF06709.11 RJW66208.1 - 0.043 14.0 0.0 5.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1196) E1_DerP2_DerF2 PF02221.15 RJW66210.1 - 3.6e-21 76.0 2.6 6.6e-12 46.0 0.1 2.2 1 1 1 2 2 2 2 ML domain E1_DerP2_DerF2 PF02221.15 RJW66211.1 - 0.0022 18.4 0.0 0.0025 18.2 0.0 1.1 1 0 0 1 1 1 1 ML domain CUB PF00431.20 RJW66213.1 - 6.1e-18 65.2 0.0 6.2e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 CUB domain MACPF PF01823.19 RJW66214.1 - 7.2e-17 62.2 0.0 1.2e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain WW_like PF17890.1 RJW66214.1 - 0.14 12.3 0.3 0.82 9.8 0.1 2.2 2 0 0 2 2 2 0 Peptidoglycan hydrolase LytB WW-like domain DUF4171 PF13775.6 RJW66217.1 - 1.1 9.7 6.2 7.2 7.1 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4171) Mito_carr PF00153.27 RJW66218.1 - 9.4e-55 182.5 0.1 4.6e-21 74.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RVT_1 PF00078.27 RJW66219.1 - 2.8e-41 141.5 0.0 7.7e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW66219.1 - 3.8e-07 29.9 0.0 9.3e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW66219.1 - 0.0028 17.2 0.1 0.0091 15.5 0.1 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-C2H2_2 PF12756.7 RJW66220.1 - 0.0071 16.7 4.7 3.4 8.0 0.8 3.5 3 1 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 RJW66220.1 - 0.01 16.2 4.3 10 6.8 0.0 4.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66220.1 - 0.017 15.9 10.5 7.7 7.7 0.2 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 RJW66220.1 - 0.06 13.6 0.2 0.06 13.6 0.2 3.5 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 RJW66220.1 - 0.065 13.3 3.4 1.4 9.0 0.8 2.8 2 0 0 2 2 2 0 BED zinc finger Ogr_Delta PF04606.12 RJW66220.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.8 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf_C2H2_ZHX PF18387.1 RJW66220.1 - 3.1 7.5 8.2 0.74 9.5 1.4 2.9 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Gelsolin PF00626.22 RJW66221.1 - 5.2e-12 45.5 0.0 1.1e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 Gelsolin repeat AKAP28 PF14469.6 RJW66222.1 - 7.3e-50 167.8 0.2 1.2e-49 167.1 0.2 1.4 1 0 0 1 1 1 1 28 kDa A-kinase anchor KIAA1430 PF13879.6 RJW66222.1 - 6.1e-11 43.0 5.6 1.2e-10 42.1 5.6 1.5 1 0 0 1 1 1 1 KIAA1430 homologue Herpes_BLRF2 PF05812.12 RJW66222.1 - 0.19 11.9 2.5 0.78 9.9 0.7 2.3 1 1 0 2 2 2 0 Herpesvirus BLRF2 protein YabA PF06156.13 RJW66222.1 - 0.66 10.6 3.8 11 6.8 2.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 RJW66223.1 - 1.2e-59 201.8 0.0 1.8e-59 201.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66223.1 - 1.8e-36 125.7 0.0 3.1e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 RJW66223.1 - 1.6e-10 40.9 12.1 1.6e-09 37.7 3.6 2.9 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 RJW66223.1 - 5.2e-08 33.5 1.9 1.5e-07 32.0 1.9 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 RJW66223.1 - 5.3e-06 25.9 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Uds1 PF15456.6 RJW66223.1 - 0.014 15.5 8.9 0.26 11.4 0.3 3.1 3 0 0 3 3 3 0 Up-regulated During Septation Peptidase_A17 PF05380.13 RJW66225.1 - 2.2e-07 31.0 0.1 3.6e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase Gelsolin PF00626.22 RJW66227.1 - 1.3e-19 69.9 0.2 3.2e-06 26.9 0.0 5.3 5 0 0 5 5 5 3 Gelsolin repeat VHP PF02209.19 RJW66227.1 - 8.7e-16 57.7 1.3 1.8e-15 56.7 1.3 1.6 1 0 0 1 1 1 1 Villin headpiece domain DUF4307 PF14155.6 RJW66228.1 - 0.0082 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4307) DEAD PF00270.29 RJW66230.1 - 2e-49 167.7 0.0 5.5e-49 166.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW66230.1 - 8.1e-23 80.9 0.0 7.5e-22 77.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW66230.1 - 6.9e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1247 PF06851.11 RJW66230.1 - 0.08 12.9 0.1 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1247) SH2 PF00017.24 RJW66231.1 - 7.5e-49 163.7 0.2 1e-23 83.2 0.0 2.3 2 0 0 2 2 2 2 SH2 domain Y_phosphatase PF00102.27 RJW66231.1 - 4e-21 75.7 0.0 1.2e-20 74.1 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase COG6 PF06419.11 RJW66232.1 - 1.4e-99 334.1 0.1 2.9e-90 303.3 0.0 2.0 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 Choline_transpo PF04515.12 RJW66233.1 - 4.2e-78 262.8 15.9 4.7e-78 262.7 15.9 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter tRNA_bind PF01588.20 RJW66234.1 - 1.2e-28 99.1 0.1 1.9e-28 98.4 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain HALZ PF02183.18 RJW66234.1 - 0.027 14.7 1.7 0.037 14.3 0.3 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper TRP_2 PF08344.11 RJW66234.1 - 0.12 12.6 0.2 0.27 11.5 0.2 1.6 1 0 0 1 1 1 0 Transient receptor ion channel II RT_RNaseH_2 PF17919.1 RJW66235.1 - 1.4e-38 131.0 0.0 2.7e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW66235.1 - 1.3e-30 105.8 0.0 3e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW66235.1 - 7.1e-24 84.6 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RJW66235.1 - 4.7e-20 71.9 0.0 1.1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW66235.1 - 1.4e-07 31.5 0.4 3.2e-07 30.3 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 RJW66235.1 - 6.2e-05 22.7 0.0 0.00016 21.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 RJW66235.1 - 0.0024 18.4 0.0 0.0057 17.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 RJW66235.1 - 0.011 16.0 0.2 0.022 15.0 0.2 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 RJW66235.1 - 0.02 15.2 0.0 0.055 13.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 RJW66235.1 - 0.041 14.5 0.0 0.1 13.3 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Choline_transpo PF04515.12 RJW66236.1 - 8.3e-14 51.5 1.6 8.3e-14 51.5 1.6 2.9 3 0 0 3 3 3 2 Plasma-membrane choline transporter RVT_1 PF00078.27 RJW66240.1 - 7.2e-11 42.0 0.0 2.6e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 RJW66241.1 - 1.9e-20 72.1 40.1 0.0001 22.6 1.2 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66241.1 - 2e-16 59.2 37.8 0.0036 18.0 4.6 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW66241.1 - 1.1e-07 31.9 42.1 0.0025 18.2 1.4 6.7 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW66241.1 - 5.6e-07 29.4 29.5 0.01 15.8 0.9 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 RJW66241.1 - 0.0042 17.4 21.3 0.11 12.9 1.3 5.4 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 RJW66241.1 - 0.0091 15.6 19.8 0.044 13.4 0.3 4.8 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 RJW66241.1 - 0.011 15.8 1.7 0.011 15.8 1.7 3.9 3 1 1 4 4 4 0 BED zinc finger zf-C2H2_jaz PF12171.8 RJW66241.1 - 0.08 13.3 29.3 0.096 13.0 2.3 5.8 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 RJW66241.1 - 0.33 11.7 11.9 11 6.9 0.2 3.5 2 1 0 2 2 2 0 zinc-ribbon family ADK_lid PF05191.14 RJW66241.1 - 0.34 10.9 13.7 2.6 8.1 0.7 4.2 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-C2H2_8 PF15909.5 RJW66241.1 - 0.86 9.9 14.8 1.3 9.3 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 RJW66241.1 - 0.98 9.8 24.1 3.4 8.1 0.2 4.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 RJW66241.1 - 1.5 9.5 18.7 5.6 7.7 1.6 5.0 2 2 3 5 5 5 0 FOXP coiled-coil domain zf-FCS PF06467.14 RJW66241.1 - 2.8 7.9 9.5 22 5.1 0.4 3.8 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif Zn-ribbon_8 PF09723.10 RJW66241.1 - 3 8.1 20.3 0.9 9.7 0.6 4.8 4 2 1 5 5 5 0 Zinc ribbon domain zf-RING_7 PF02591.15 RJW66241.1 - 5.5 7.3 11.4 31 4.9 0.3 4.6 5 0 0 5 5 5 0 C4-type zinc ribbon domain zf-C2H2 PF00096.26 RJW66243.1 - 1.1e-10 41.4 29.7 0.00023 21.4 2.3 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW66243.1 - 5.9e-05 23.3 19.1 0.89 10.1 0.1 5.0 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW66243.1 - 9.1e-05 23.0 32.0 0.004 17.9 2.1 4.7 5 0 0 5 5 5 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 RJW66243.1 - 0.0016 18.5 1.4 0.0016 18.5 1.4 3.4 3 0 0 3 3 3 1 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 RJW66243.1 - 0.26 10.9 10.1 2.8 7.7 2.1 3.2 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain UPF0547 PF10571.9 RJW66243.1 - 0.52 10.4 0.2 0.52 10.4 0.2 3.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-C2H2_2 PF12756.7 RJW66243.1 - 2.8 8.3 16.3 5.2 7.5 0.3 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 RJW66243.1 - 3.3 8.4 8.9 0.52 11.0 0.8 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain Prominin PF05478.11 RJW66244.1 - 0.0037 15.3 5.3 0.0038 15.3 5.3 1.1 1 0 0 1 1 1 1 Prominin HTH_Crp_2 PF13545.6 RJW66244.1 - 0.032 14.2 1.7 1.4 8.9 0.2 2.2 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain LdpA_C PF12617.8 RJW66244.1 - 0.052 13.1 1.5 0.1 12.2 0.2 2.0 1 1 0 2 2 2 0 Iron-Sulfur binding protein C terminal Snapin_Pallidin PF14712.6 RJW66244.1 - 0.055 13.9 7.0 0.12 12.8 7.0 1.7 1 0 0 1 1 1 0 Snapin/Pallidin Tn7_Tnp_TnsA_C PF08721.11 RJW66244.1 - 0.081 13.6 6.2 27 5.5 0.0 3.4 2 1 0 2 2 2 0 TnsA endonuclease C terminal Retrotrans_gag PF03732.17 RJW66244.1 - 0.16 12.2 2.6 0.4 11.0 1.9 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein Nup88 PF10168.9 RJW66244.1 - 0.19 9.5 11.4 0.2 9.4 11.4 1.2 1 0 0 1 1 1 0 Nuclear pore component Methyltransf_14 PF08484.11 RJW66244.1 - 0.26 11.1 2.9 0.25 11.1 0.4 2.2 3 0 0 3 3 3 0 C-methyltransferase C-terminal domain NPV_P10 PF05531.12 RJW66244.1 - 0.37 11.3 3.4 1.9 9.0 3.4 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SpecificRecomb PF10136.9 RJW66244.1 - 0.39 9.0 7.4 0.54 8.5 7.4 1.2 1 0 0 1 1 1 0 Site-specific recombinase Med21 PF11221.8 RJW66244.1 - 0.5 10.6 18.5 1.4 9.2 17.5 2.2 1 1 0 1 1 1 0 Subunit 21 of Mediator complex YojJ PF10372.9 RJW66244.1 - 0.91 9.7 5.7 0.86 9.7 0.7 2.7 1 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF935 PF06074.12 RJW66244.1 - 1.6 7.4 16.7 0.36 9.5 12.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF935) Tmemb_cc2 PF10267.9 RJW66244.1 - 2 7.5 23.1 2.2 7.3 1.3 1.9 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein SOBP PF15279.6 RJW66244.1 - 2 8.9 12.5 2.8 8.5 12.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4810 PF16068.5 RJW66244.1 - 2.7 8.6 6.4 0.95 10.1 0.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4810) POX PF07526.11 RJW66244.1 - 6.5 7.3 19.3 2.7 8.6 3.9 2.4 1 1 1 2 2 2 0 Associated with HOX Goodbye PF17109.5 RJW66244.1 - 7 7.1 9.5 0.25 11.8 0.9 2.7 1 1 2 3 3 3 0 fungal STAND N-terminal Goodbye domain OMPdecase PF00215.24 RJW66245.1 - 1e-48 165.9 0.0 3e-26 92.4 0.0 2.5 2 1 1 3 3 3 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 RJW66245.1 - 6.1e-11 42.1 0.3 1.3e-10 41.1 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF460 PF04312.13 RJW66245.1 - 0.011 15.4 0.1 0.4 10.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF460) NADH_dh_m_C1 PF15088.6 RJW66246.1 - 0.056 13.1 0.3 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial TPR_19 PF14559.6 RJW66247.1 - 1.1e-06 29.1 4.6 0.00013 22.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW66247.1 - 2.6e-06 27.8 7.8 0.99 10.4 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 RJW66247.1 - 6.1e-06 25.8 5.1 0.012 15.5 0.1 3.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RJW66247.1 - 2.4e-05 24.4 0.8 0.089 12.9 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW66247.1 - 0.0014 18.6 2.2 0.021 14.9 0.5 5.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW66247.1 - 0.007 16.7 1.6 31 5.3 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW66247.1 - 0.009 16.0 8.1 0.86 9.8 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW66247.1 - 0.034 14.4 5.5 6.5 7.1 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 RJW66247.1 - 0.16 11.6 8.8 5.2 6.8 0.2 4.5 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 RJW66247.1 - 0.27 11.5 9.9 0.45 10.9 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat 7tm_1 PF00001.21 RJW66248.1 - 3.9e-71 239.4 10.5 5.5e-71 239.0 10.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW66248.1 - 7.2e-10 38.9 11.3 7.2e-10 38.9 11.3 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RJW66248.1 - 7.6e-09 35.3 12.4 7.6e-09 35.3 12.4 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RJW66248.1 - 0.0056 16.5 10.4 0.0056 16.5 10.4 2.4 2 1 0 2 2 2 1 Olfactory receptor CrgA PF06781.12 RJW66248.1 - 4.5 7.4 6.8 35 4.5 0.8 3.5 3 0 0 3 3 3 0 Cell division protein CrgA SET PF00856.28 RJW66250.1 - 8.2e-27 94.6 0.2 1.6e-17 64.4 0.0 3.4 3 1 0 3 3 3 2 SET domain Tudor_4 PF18358.1 RJW66250.1 - 4.2e-23 80.7 0.0 1e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain TUDOR_5 PF18359.1 RJW66250.1 - 1.2e-20 72.9 0.1 3e-20 71.7 0.1 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Pre-SET PF05033.16 RJW66250.1 - 4.6e-17 62.7 7.2 4.6e-17 62.7 7.2 2.5 2 0 0 2 2 2 1 Pre-SET motif MBD PF01429.19 RJW66250.1 - 4.6e-05 23.0 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain 7tm_1 PF00001.21 RJW66251.1 - 2.6e-53 181.0 8.7 3.5e-53 180.6 8.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW66251.1 - 3.9e-08 33.0 18.3 6.3e-06 25.8 10.5 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RJW66251.1 - 0.0052 16.5 15.8 0.0052 16.5 15.8 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Ctr PF04145.15 RJW66251.1 - 1.4 9.5 4.2 76 3.9 4.1 2.7 1 1 0 1 1 1 0 Ctr copper transporter family 7tm_1 PF00001.21 RJW66252.1 - 8.4e-51 172.8 7.6 1.1e-50 172.4 7.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW66252.1 - 3.1e-05 23.5 24.6 0.0037 16.7 15.6 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx HTH_46 PF15977.5 RJW66252.1 - 0.094 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding 7TM_GPCR_Srx PF10328.9 RJW66252.1 - 0.11 12.1 24.6 0.017 14.7 19.5 2.2 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Ctr PF04145.15 RJW66252.1 - 0.47 11.1 2.6 13 6.4 2.6 2.4 1 1 0 1 1 1 0 Ctr copper transporter family ALMS_motif PF15309.6 RJW66253.1 - 0.00029 21.3 1.7 0.00029 21.3 1.7 4.1 4 0 0 4 4 4 2 ALMS motif PaaX_C PF08223.11 RJW66253.1 - 0.01 16.1 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain 7tm_1 PF00001.21 RJW66256.1 - 9.9e-65 218.5 0.2 1.7e-64 217.7 0.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW66256.1 - 2.3e-06 27.2 11.8 2.3e-06 27.2 11.8 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RJW66256.1 - 4.7e-05 23.1 16.7 0.00013 21.7 16.7 1.7 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RJW66256.1 - 0.0097 15.7 10.7 0.0097 15.7 10.7 2.0 2 0 0 2 2 2 1 Olfactory receptor CUB PF00431.20 RJW66257.1 - 6.8e-51 171.2 0.0 3.3e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.20 RJW66257.1 - 0.00049 19.9 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 CUB-like domain UPF0556 PF10572.9 RJW66257.1 - 0.17 11.4 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0556 Tcp10_C PF07202.13 RJW66257.1 - 0.18 11.7 0.0 9.5 6.1 0.0 2.2 2 0 0 2 2 2 0 T-complex protein 10 C-terminus Glycos_transf_2 PF00535.26 RJW66259.1 - 1.5e-32 112.7 0.0 2.1e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RJW66259.1 - 1.2e-14 54.8 0.0 1.6e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 RJW66259.1 - 0.00026 20.5 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 RJW66259.1 - 0.00028 20.5 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 RJW66259.1 - 0.2 12.2 0.0 0.47 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Spc7 PF08317.11 RJW66260.1 - 0.0068 15.3 6.5 0.011 14.7 6.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3584 PF12128.8 RJW66260.1 - 0.014 12.9 4.9 0.021 12.4 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LRS4 PF10422.9 RJW66260.1 - 0.12 11.9 4.6 0.046 13.3 1.6 1.7 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 ADIP PF11559.8 RJW66260.1 - 1.6 8.8 7.4 2.9 8.0 7.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 RJW66260.1 - 2.4 8.8 6.7 1.5 9.5 3.8 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Dynactin PF12455.8 RJW66262.1 - 1.4e-21 77.0 3.9 1.4e-21 77.0 3.9 3.3 3 0 0 3 3 2 1 Dynein associated protein CAP_GLY PF01302.25 RJW66262.1 - 3.8e-17 62.1 0.1 7.5e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain GAS PF13851.6 RJW66262.1 - 6.8e-05 22.3 68.3 0.0099 15.2 26.7 3.8 2 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 RJW66262.1 - 0.23 11.5 84.4 0.64 10.0 16.2 6.1 2 2 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 RJW66262.1 - 0.58 10.7 27.7 6.5 7.3 1.7 5.6 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein CRIC_ras_sig PF10534.9 RJW66262.1 - 0.81 9.9 6.5 0.38 11.0 1.1 3.0 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras Spc7 PF08317.11 RJW66262.1 - 0.82 8.5 74.8 0.16 10.8 17.6 4.3 2 2 2 4 4 4 0 Spc7 kinetochore protein Atg14 PF10186.9 RJW66262.1 - 0.97 8.4 47.5 0.33 10.0 7.6 3.2 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 RJW66262.1 - 1.3 8.6 69.4 7 6.1 6.4 5.0 2 2 1 3 3 3 0 Intermediate filament protein TACC_C PF05010.14 RJW66262.1 - 5.8 6.7 57.5 2.7 7.7 16.1 3.3 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PI_PP_I PF18363.1 RJW66262.1 - 6.2 7.1 7.8 1.2 9.3 0.8 3.1 2 1 2 4 4 4 0 Phosphoinositide phosphatase insertion domain DUF1664 PF07889.12 RJW66262.1 - 7.3 6.6 36.7 0.17 11.9 6.5 4.9 2 2 3 6 6 6 0 Protein of unknown function (DUF1664) UQ_con PF00179.26 RJW66263.1 - 2.4e-36 124.5 0.1 3.1e-36 124.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UDPGP PF01704.18 RJW66264.1 - 7.4e-48 163.2 0.0 3.5e-45 154.4 0.0 2.0 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase NTP_transferase PF00483.23 RJW66264.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 Nucleotidyl transferase T7SS_ESX_EspC PF10824.8 RJW66264.1 - 0.075 13.5 0.0 0.25 11.9 0.0 1.8 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm NTP_transf_3 PF12804.7 RJW66264.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain Asp PF00026.23 RJW66265.1 - 4.5e-33 115.0 0.0 5.8e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW66265.1 - 0.0035 17.6 1.3 0.26 11.5 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal UPF0113_N PF17833.1 RJW66268.1 - 1.3e-24 86.6 0.2 2e-24 85.9 0.2 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 RJW66268.1 - 1e-23 83.3 0.0 2e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 RJW66268.1 - 0.0035 17.3 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 PUA domain HLH PF00010.26 RJW66271.1 - 6.6e-09 35.6 0.2 6.6e-09 35.6 0.2 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain PNP_UDP_1 PF01048.20 RJW66272.1 - 6.7e-27 94.2 0.2 7.9e-27 94.0 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily zf_CCCH_4 PF18345.1 RJW66275.1 - 8e-05 22.6 2.0 8e-05 22.6 2.0 2.3 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 RJW66275.1 - 0.0022 17.9 9.3 0.0029 17.5 0.3 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RJW66275.1 - 0.0082 15.9 1.5 0.0082 15.9 1.5 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 RJW66275.1 - 0.087 13.5 2.5 0.27 12.0 0.0 2.6 3 0 0 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 RJW66275.1 - 0.14 12.4 1.5 25 5.1 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 RJW66275.1 - 0.26 11.8 11.8 0.18 12.3 1.7 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger HECT PF00632.25 RJW66277.1 - 1.5e-25 90.3 0.1 1.9e-25 90.0 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ASC PF00858.24 RJW66277.1 - 0.068 12.1 0.9 0.085 11.8 0.9 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel RVT_1 PF00078.27 RJW66278.1 - 4.8e-45 153.8 0.0 8.2e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW66278.1 - 8.5e-07 28.7 1.1 2.4e-06 27.3 0.4 2.2 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Phage_Gp23 PF10669.9 RJW66278.1 - 6.9 7.0 8.8 17 5.8 8.8 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) AA_kinase PF00696.28 RJW66279.1 - 4.5e-32 111.6 0.0 4e-31 108.4 0.0 2.3 2 1 0 2 2 2 1 Amino acid kinase family Aldedh PF00171.22 RJW66279.1 - 1.3e-11 43.7 1.6 7.5e-10 37.9 0.2 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Aldo_ket_red PF00248.21 RJW66280.1 - 1.8e-52 178.4 0.0 2.6e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Oxysterol_BP PF01237.18 RJW66281.1 - 5.4e-16 58.4 0.0 7.9e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 RJW66281.1 - 7e-08 32.9 0.0 1.3e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 RJW66281.1 - 7.3e-05 23.0 0.1 0.00023 21.4 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 RJW66281.1 - 0.00013 22.2 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 RJW66281.1 - 0.098 12.5 1.1 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Dynein_light PF01221.18 RJW66283.1 - 1.5e-19 70.1 3.2 8e-19 67.7 0.5 2.1 2 0 0 2 2 2 1 Dynein light chain type 1 EF-hand_7 PF13499.6 RJW66283.1 - 3.7e-05 24.1 3.3 5.5e-05 23.5 0.7 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW66283.1 - 0.0016 18.2 0.8 2.2 8.4 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain HTH_Mga PF08280.11 RJW66283.1 - 0.0033 17.4 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain EF-hand_1 PF00036.32 RJW66283.1 - 0.013 15.0 0.2 0.5 10.0 0.0 3.0 2 1 0 2 2 2 0 EF hand AbiJ_NTD4 PF18863.1 RJW66283.1 - 0.017 15.6 0.5 0.017 15.6 0.5 1.8 2 1 0 2 2 2 0 AbiJ N-terminal domain 4 DUF3038 PF11237.8 RJW66283.1 - 0.038 14.0 0.9 0.069 13.2 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3038) GPHH PF16905.5 RJW66283.1 - 0.045 13.5 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_9 PF14658.6 RJW66283.1 - 0.077 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Imm6 PF14434.6 RJW66283.1 - 0.08 12.9 1.2 0.1 12.5 0.3 1.7 2 0 0 2 2 2 0 Immunity protein Imm6 EF-hand_4 PF12763.7 RJW66283.1 - 0.096 12.6 0.3 0.19 11.7 0.2 1.7 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand zf-A20 PF01754.16 RJW66284.1 - 2.9e-12 46.3 7.9 6.8e-12 45.1 7.9 1.7 1 0 0 1 1 1 1 A20-like zinc finger TMEM190 PF15431.6 RJW66285.1 - 0.031 14.4 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 RabGAP-TBC PF00566.18 RJW66286.1 - 4.3e-40 137.7 1.1 5.8e-40 137.2 1.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 RJW66287.1 - 8.3e-07 28.5 0.0 0.00064 19.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RJW66287.1 - 9.5e-07 27.9 0.1 0.0017 17.8 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW66287.1 - 1.4e-05 25.4 0.1 4.6e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW66287.1 - 0.00051 19.8 0.1 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 RJW66287.1 - 0.0024 18.1 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain OCIA PF07051.11 RJW66288.1 - 8.4e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) ABA_GPCR PF12430.8 RJW66289.1 - 1.8e-36 125.6 9.9 1.8e-36 125.6 9.9 2.4 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 RJW66289.1 - 2.7e-26 91.4 0.1 5.8e-26 90.4 0.1 1.6 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal ANAPC4_WD40 PF12894.7 RJW66290.1 - 7.7e-07 29.3 1.4 0.34 11.2 0.0 5.7 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW66290.1 - 1.6e-05 25.5 7.7 0.31 12.0 0.0 6.0 4 2 2 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 RJW66290.1 - 0.0017 18.2 0.1 13 5.6 0.0 4.3 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.20 RJW66290.1 - 0.0022 17.9 0.5 0.2 11.6 0.1 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 RJW66290.1 - 0.0093 15.1 3.9 0.4 9.7 0.1 3.4 3 1 0 3 3 3 2 Coatomer WD associated region IKI3 PF04762.12 RJW66290.1 - 0.0094 14.0 1.6 0.39 8.6 0.1 2.8 3 0 0 3 3 3 2 IKI3 family Tau95 PF09734.9 RJW66291.1 - 1.9e-36 125.9 0.5 3.3e-36 125.2 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain WD40 PF00400.32 RJW66291.1 - 6e-19 68.0 17.5 0.00019 22.2 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Tau95_N PF17682.1 RJW66291.1 - 8.5e-15 55.1 0.0 2.9e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 Tau95 Triple barrel domain PBP_like_2 PF12849.7 RJW66291.1 - 0.013 15.1 0.1 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 PBP superfamily domain Dynein_light PF01221.18 RJW66293.1 - 5.8e-16 58.6 2.4 7.7e-16 58.2 0.3 1.9 2 0 0 2 2 2 1 Dynein light chain type 1 Surp PF01805.20 RJW66294.1 - 5.7e-31 106.3 0.2 4.2e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 Surp module DRY_EERY PF09750.9 RJW66294.1 - 7.9e-27 94.2 0.3 7.9e-27 94.2 0.3 2.3 2 0 0 2 2 2 1 Alternative splicing regulator MULE PF10551.9 RJW66295.1 - 4e-05 23.9 0.1 0.00019 21.8 0.0 2.1 2 0 0 2 2 2 1 MULE transposase domain Serpin PF00079.20 RJW66296.1 - 2.5e-63 214.6 0.0 2.8e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) PIP5K PF01504.18 RJW66297.1 - 7.6e-64 215.6 0.0 1.1e-62 211.7 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Serpin PF00079.20 RJW66298.1 - 6.9e-68 229.6 0.2 8.4e-68 229.4 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) RasGEF_N_2 PF14663.6 RJW66298.1 - 0.087 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TOM6p PF15184.6 RJW66299.1 - 0.08 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog Cadherin PF00028.17 RJW66301.1 - 1.3e-59 198.6 0.2 2.5e-17 63.1 0.0 9.9 9 1 0 9 9 9 7 Cadherin domain Cadherin_2 PF08266.12 RJW66301.1 - 3.3e-08 33.3 0.0 7.4e-05 22.5 0.0 3.1 2 0 0 2 2 2 2 Cadherin-like Cadherin_3 PF16184.5 RJW66301.1 - 0.00055 19.9 4.5 15 5.7 0.0 5.5 5 2 0 5 5 5 3 Cadherin-like Cadherin_C_2 PF16492.5 RJW66301.1 - 0.016 15.9 0.0 0.075 13.8 0.0 2.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF2157 PF09925.9 RJW66301.1 - 0.19 11.5 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Invasin_D3 PF09134.10 RJW66301.1 - 0.64 10.4 2.6 1.4 9.2 0.2 2.9 3 0 0 3 3 3 0 Invasin, domain 3 VPS9 PF02204.18 RJW66303.1 - 3.4e-22 78.6 0.0 1.2e-21 76.8 0.0 2.0 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 RJW66303.1 - 1.6e-15 57.1 0.1 1.2e-14 54.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) MbeD_MobD PF04899.12 RJW66303.1 - 0.017 15.2 1.2 1.2 9.3 0.3 2.6 2 0 0 2 2 2 0 MbeD/MobD like DUF812 PF05667.11 RJW66303.1 - 0.035 13.0 0.1 0.045 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Serpin PF00079.20 RJW66304.1 - 2.8e-54 184.8 0.1 3.2e-54 184.6 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) EF-hand_7 PF13499.6 RJW66306.1 - 0.016 15.7 0.1 0.026 15.0 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 RJW66306.1 - 0.017 14.6 0.4 0.048 13.2 0.4 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 RJW66306.1 - 0.037 14.0 0.5 0.1 12.6 0.5 1.7 1 0 0 1 1 1 0 EF-hand domain Amidohydro_2 PF04909.14 RJW66307.1 - 6.2e-27 95.1 0.0 2.2e-26 93.3 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase GSCFA PF08885.11 RJW66307.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 GSCFA family Aldo_ket_red PF00248.21 RJW66308.1 - 8.6e-25 87.5 0.0 4.5e-24 85.2 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family ETF_QO PF05187.13 RJW66309.1 - 3.1e-47 159.0 0.1 5.4e-47 158.2 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 RJW66309.1 - 1.1e-10 41.7 0.3 4.2e-05 23.3 0.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RJW66309.1 - 4.5e-10 39.2 0.2 3e-05 23.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 RJW66309.1 - 1e-09 38.5 0.1 7e-09 35.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RJW66309.1 - 2.4e-07 30.3 0.0 8.4e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 RJW66309.1 - 8.1e-07 28.6 0.0 2.1e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RJW66309.1 - 1.5e-06 27.4 0.2 0.0083 15.0 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 RJW66309.1 - 3.1e-05 23.5 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 RJW66309.1 - 0.0002 21.9 0.1 0.2 12.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RJW66309.1 - 0.00035 19.4 0.1 0.00081 18.2 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 RJW66309.1 - 0.00069 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 RJW66309.1 - 0.00095 18.3 0.0 0.0059 15.7 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 RJW66309.1 - 0.0011 18.3 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RJW66309.1 - 0.0038 16.5 0.0 0.01 15.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Fer4_7 PF12838.7 RJW66309.1 - 0.031 14.9 1.1 0.08 13.5 1.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 RJW66309.1 - 0.079 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_21 PF14697.6 RJW66309.1 - 0.12 12.5 1.1 0.25 11.5 1.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.6 RJW66309.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_2 PF12797.7 RJW66309.1 - 0.14 12.3 0.5 0.44 10.8 0.5 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain Aquarius_N PF16399.5 RJW66310.1 - 1.9e-224 747.2 4.2 5.6e-156 520.8 0.3 3.1 2 1 1 3 3 3 3 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 RJW66310.1 - 1.7e-30 106.7 0.0 3.3e-29 102.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 RJW66310.1 - 1.2e-25 90.3 0.0 4.6e-25 88.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RJW66310.1 - 3.1e-10 40.6 0.9 1.1e-09 38.7 0.1 2.4 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 RJW66310.1 - 1e-07 31.9 0.0 0.00065 19.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 RJW66310.1 - 9.1e-06 25.8 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 RJW66310.1 - 1.7e-05 24.5 0.0 6.2e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 RJW66310.1 - 0.0012 18.6 0.5 0.0029 17.4 0.5 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.29 RJW66310.1 - 0.0015 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 RJW66310.1 - 0.002 18.5 0.6 0.012 16.0 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain DUF2075 PF09848.9 RJW66310.1 - 0.0036 16.6 0.4 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 RJW66310.1 - 0.0036 17.7 0.0 0.0094 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RJW66310.1 - 0.0054 17.0 0.1 0.064 13.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain DnaB_C PF03796.15 RJW66310.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Viral_helicase1 PF01443.18 RJW66310.1 - 0.0098 15.7 0.2 0.97 9.1 0.1 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 RJW66310.1 - 0.019 14.4 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 RJW66310.1 - 0.03 13.4 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 RJW66310.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 RJW66310.1 - 0.052 12.9 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC RecA PF00154.21 RJW66310.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Pes-10 PF07149.11 RJW66310.1 - 0.097 11.7 0.1 2.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Pes-10 GPHH PF16905.5 RJW66310.1 - 0.12 12.2 0.2 2.8 7.8 0.1 2.6 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Filament PF00038.21 RJW66312.1 - 0.00036 20.2 0.3 0.00048 19.8 0.3 1.2 1 0 0 1 1 1 1 Intermediate filament protein Filament PF00038.21 RJW66314.1 - 2.1e-15 57.1 52.7 4.6e-15 56.0 52.7 1.5 1 1 0 1 1 1 1 Intermediate filament protein ATG16 PF08614.11 RJW66314.1 - 0.015 15.5 14.3 0.015 15.5 14.3 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4942 PF13708.6 RJW66314.1 - 0.016 15.1 4.5 0.043 13.8 1.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4942) ApoLp-III PF07464.11 RJW66314.1 - 0.055 13.6 17.8 0.99 9.5 8.4 3.5 2 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) IKKbetaNEMObind PF12179.8 RJW66314.1 - 0.056 13.5 2.3 0.24 11.4 0.2 3.0 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain SHE3 PF17078.5 RJW66314.1 - 0.34 10.6 35.3 1.2 8.8 5.7 3.1 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 DUF3584 PF12128.8 RJW66314.1 - 0.68 7.4 45.8 0.8 7.1 45.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 RJW66314.1 - 1.9 8.9 12.3 1.1 9.7 0.1 4.0 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) IFT57 PF10498.9 RJW66314.1 - 5.1 6.0 34.0 1.1 8.1 13.9 3.1 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Hormone_6 PF00236.18 RJW66316.1 - 0.0075 16.2 1.2 2.3 8.3 0.1 2.7 2 0 0 2 2 2 2 Glycoprotein hormone Phospholip_A2_2 PF05826.12 RJW66317.1 - 1.3e-29 102.3 3.7 1.6e-29 102.0 3.7 1.1 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 RJW66317.1 - 0.22 12.0 12.0 8.3 6.9 12.0 2.2 1 1 0 1 1 1 0 Phospholipase A2 UDG PF03167.19 RJW66319.1 - 6.9e-24 84.6 0.0 2.3e-23 82.9 0.0 1.8 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily LTD PF00932.19 RJW66319.1 - 0.00066 20.0 0.0 0.061 13.7 0.0 2.9 2 1 0 2 2 2 1 Lamin Tail Domain PAF PF15715.5 RJW66319.1 - 0.069 13.7 0.9 0.13 12.8 0.9 1.5 1 0 0 1 1 1 0 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 RJW66322.1 - 7.7e-05 22.9 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CKS PF01111.19 RJW66323.1 - 4e-35 119.9 4.1 6.9e-35 119.1 4.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit NERD PF08378.11 RJW66323.1 - 0.12 12.8 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Nuclease-related domain DUF1965 PF09248.10 RJW66323.1 - 0.12 12.1 0.0 0.59 9.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) CBS PF00571.28 RJW66324.1 - 3.5e-05 24.1 0.0 6.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 CBS domain Ldh_1_C PF02866.18 RJW66325.1 - 2.5e-50 170.7 0.0 3.7e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 RJW66325.1 - 7.6e-45 152.5 0.0 1.3e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RJW66325.1 - 0.043 14.1 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 RJW66325.1 - 0.099 13.1 0.1 0.27 11.7 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain SK_channel PF03530.14 RJW66326.1 - 9e-39 132.0 4.3 9e-39 132.0 4.3 1.9 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 RJW66326.1 - 7.1e-14 51.5 2.5 7.1e-14 51.5 2.5 2.3 2 0 0 2 2 2 1 Ion channel ELL PF10390.9 RJW66327.1 - 2.4e-25 89.6 0.0 4e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 RJW66327.1 - 6.2e-14 52.5 0.3 2.7e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Occludin homology domain HTH_Tnp_1 PF01527.20 RJW66327.1 - 0.00048 20.4 0.2 0.0013 19.0 0.2 1.7 1 0 0 1 1 1 1 Transposase FH2 PF02181.23 RJW66331.1 - 2.9e-27 95.8 1.0 3.9e-27 95.3 1.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF1287 PF06940.11 RJW66331.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) DUF1677 PF07911.13 RJW66331.1 - 0.03 14.7 0.0 0.091 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Phage_TAC_3 PF06896.11 RJW66331.1 - 0.048 14.3 0.8 9 6.9 0.0 2.2 1 1 0 2 2 2 0 Phage tail assembly chaperone proteins, TAC Chromadorea_ALT PF05535.12 RJW66331.1 - 0.091 13.0 0.7 0.19 12.0 0.7 1.5 1 0 0 1 1 1 0 Chromadorea ALT protein Pkinase PF00069.25 RJW66332.1 - 3.2e-26 92.3 0.0 4e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66332.1 - 4.4e-06 26.2 0.0 6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 RJW66333.1 - 4.5e-11 42.7 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Homeodomain PF00046.29 RJW66338.1 - 1.4e-21 76.1 9.7 2.4e-21 75.3 9.7 1.4 1 0 0 1 1 1 1 Homeodomain Terminase_5 PF06056.12 RJW66338.1 - 0.099 12.5 0.4 0.45 10.4 0.2 2.1 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Homeobox_KN PF05920.11 RJW66338.1 - 0.1 12.5 0.6 0.26 11.2 0.6 1.7 1 0 0 1 1 1 0 Homeobox KN domain RIO1 PF01163.22 RJW66340.1 - 2.5e-33 115.3 4.6 3.4e-33 114.8 0.1 2.5 2 1 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 RJW66340.1 - 9.1e-20 70.7 0.0 2.3e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 RJW66340.1 - 2.2e-05 23.9 0.3 0.00012 21.5 0.3 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW66340.1 - 0.0035 17.3 1.0 1 9.2 0.3 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF5521 PF17659.1 RJW66340.1 - 1.8 6.3 6.1 2.6 5.8 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Phospholip_A2_2 PF05826.12 RJW66341.1 - 1.2e-28 99.2 1.9 1.9e-28 98.5 1.9 1.3 1 0 0 1 1 1 1 Phospholipase A2 TBPIP_N PF15517.6 RJW66341.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 TBP-interacting protein N-terminus Phospholip_A2_1 PF00068.19 RJW66341.1 - 1.1 9.8 7.2 1.8 9.0 1.3 2.5 1 1 1 2 2 2 0 Phospholipase A2 Phospholip_A2_2 PF05826.12 RJW66343.1 - 4.4e-30 103.8 7.0 1.1e-29 102.5 7.0 1.7 1 0 0 1 1 1 1 Phospholipase A2 CBS PF00571.28 RJW66345.1 - 7.3e-10 39.1 0.0 1.7e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.25 RJW66346.1 - 2.9e-34 118.6 0.1 3.4e-34 118.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66346.1 - 4.6e-23 81.8 0.0 5.7e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 RJW66346.1 - 0.0018 18.0 0.2 0.0035 17.0 0.2 1.7 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 RJW66346.1 - 0.0053 16.1 0.3 0.012 15.0 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ALF PF03752.13 RJW66347.1 - 0.00034 20.5 0.1 1.5 8.8 0.0 2.6 2 0 0 2 2 2 2 Short repeats of unknown function DUF1205 PF06722.12 RJW66347.1 - 0.066 13.3 0.4 7.6 6.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) ATP-synt_ab_C PF00306.27 RJW66351.1 - 0.22 11.8 0.0 0.34 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain Carb_bind PF10645.9 RJW66351.1 - 4.5 7.6 6.4 0.39 11.0 0.5 2.2 3 0 0 3 3 3 0 Carbohydrate binding TACC_C PF05010.14 RJW66352.1 - 7.6e-46 156.4 25.6 8.2e-46 156.3 25.6 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-F_leu_zip PF10473.9 RJW66352.1 - 0.0021 18.1 29.0 0.21 11.6 1.1 3.0 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 RJW66352.1 - 0.0026 18.3 28.0 0.046 14.3 11.4 2.3 1 1 1 2 2 2 1 Apg6 coiled-coil region FlaC_arch PF05377.11 RJW66352.1 - 0.014 15.8 8.9 2.6 8.5 0.1 3.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 RJW66352.1 - 0.018 15.3 18.3 0.018 15.3 18.3 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Med9 PF07544.13 RJW66352.1 - 0.027 14.5 1.8 0.027 14.5 1.8 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.6 RJW66352.1 - 0.041 12.5 19.9 0.034 12.8 3.9 2.0 1 1 1 2 2 2 0 AAA domain End3 PF12761.7 RJW66352.1 - 0.058 13.6 22.0 0.28 11.4 17.5 2.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Filament PF00038.21 RJW66352.1 - 0.063 12.9 23.8 0.05 13.2 15.3 2.6 1 1 1 2 2 2 0 Intermediate filament protein DUF3584 PF12128.8 RJW66352.1 - 0.071 10.6 17.6 0.12 9.9 17.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CLZ PF16526.5 RJW66352.1 - 0.081 13.3 17.4 0.51 10.7 5.5 3.6 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snf7 PF03357.21 RJW66352.1 - 0.083 12.5 0.5 0.083 12.5 0.5 2.9 2 1 1 3 3 3 0 Snf7 DUF948 PF06103.11 RJW66352.1 - 0.14 12.4 0.4 0.14 12.4 0.4 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Tektin PF03148.14 RJW66352.1 - 0.15 10.8 20.1 0.73 8.5 1.1 3.0 1 1 2 3 3 3 0 Tektin family Occludin_ELL PF07303.13 RJW66352.1 - 0.18 12.5 14.8 1 10.1 0.6 3.2 1 1 2 3 3 3 0 Occludin homology domain DUF5082 PF16888.5 RJW66352.1 - 0.42 10.9 14.8 0.1 12.9 8.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF641 PF04859.12 RJW66352.1 - 0.48 10.8 22.3 1.2 9.5 4.8 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) SKA1 PF07160.12 RJW66352.1 - 0.51 10.2 19.3 1.6 8.6 4.5 3.0 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 BRE1 PF08647.11 RJW66352.1 - 0.55 10.3 25.2 6.7 6.9 5.9 4.0 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 RJW66352.1 - 0.88 9.8 26.0 0.38 10.9 6.7 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 RJW66352.1 - 1.2 8.7 17.4 3.5 7.1 17.4 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 RJW66352.1 - 1.2 9.1 27.2 0.29 11.2 2.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 RJW66352.1 - 1.5 7.7 27.8 0.75 8.6 4.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 RJW66352.1 - 1.5 9.0 15.8 6.1 7.0 7.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4472 PF14739.6 RJW66352.1 - 1.6 9.5 24.5 7.6 7.3 14.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Ax_dynein_light PF10211.9 RJW66352.1 - 1.6 8.6 24.0 0.13 12.2 6.0 2.8 1 1 1 2 2 2 0 Axonemal dynein light chain FH2 PF02181.23 RJW66352.1 - 1.7 7.7 16.6 1.5 7.9 4.2 2.7 1 1 2 3 3 3 0 Formin Homology 2 Domain DUF3450 PF11932.8 RJW66352.1 - 2 7.7 23.9 5.6 6.2 4.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 RJW66352.1 - 2.4 8.8 14.5 12 6.6 6.1 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal GAS PF13851.6 RJW66352.1 - 2.8 7.2 26.8 5.1 6.4 8.1 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 RJW66352.1 - 3.3 8.4 17.6 4.4 8.0 4.2 3.1 2 1 1 3 3 3 0 Initiation control protein YabA DUF4200 PF13863.6 RJW66352.1 - 3.5 8.1 30.7 24 5.4 0.6 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF2203 PF09969.9 RJW66352.1 - 3.8 8.3 14.4 6.9e+02 1.0 14.3 2.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.22 RJW66352.1 - 4.2 7.7 23.2 0.21 11.9 0.8 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CENP-H PF05837.12 RJW66352.1 - 4.7 7.7 25.0 11 6.5 8.4 3.3 1 1 2 3 3 3 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 RJW66352.1 - 5.7 7.0 14.7 11 6.1 0.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 RJW66352.1 - 7.3 5.0 21.4 9.3 4.7 21.4 1.1 1 0 0 1 1 1 0 Macoilin family TPR_MLP1_2 PF07926.12 RJW66352.1 - 7.5 6.6 28.8 45 4.1 0.3 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CorA PF01544.18 RJW66352.1 - 7.9 5.7 9.1 11 5.3 6.4 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ZnuA PF01297.17 RJW66352.1 - 9.7 5.5 8.1 12 5.2 6.5 1.9 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic SET PF00856.28 RJW66354.1 - 8.9e-22 78.3 0.0 2.6e-21 76.7 0.0 1.8 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 RJW66354.1 - 1.2e-15 58.1 2.1 1.2e-15 58.1 2.1 2.5 2 1 0 2 2 2 1 Pre-SET motif Saccharop_dh_N PF04455.12 RJW66354.1 - 0.058 13.8 0.0 19 5.7 0.0 2.4 2 0 0 2 2 2 0 LOR/SDH bifunctional enzyme conserved region AWS PF17907.1 RJW66354.1 - 2 8.5 8.2 0.61 10.2 2.2 2.7 2 0 0 2 2 2 0 AWS domain Homeodomain PF00046.29 RJW66355.1 - 7.3e-20 70.6 6.3 2.1e-19 69.1 6.3 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW66355.1 - 0.075 13.0 0.1 0.26 11.2 0.1 2.0 1 0 0 1 1 1 0 Homeobox KN domain Phage_Coat_A PF05357.13 RJW66355.1 - 0.11 12.3 0.3 0.39 10.5 0.2 1.9 2 0 0 2 2 2 0 Phage Coat Protein A Ldh_1_N PF00056.23 RJW66356.1 - 8e-22 77.8 0.5 2.3e-21 76.3 0.5 1.7 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RJW66356.1 - 0.0041 16.7 0.3 0.022 14.3 0.3 1.9 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 RJW66356.1 - 0.009 16.0 0.6 0.52 10.3 0.0 2.3 1 1 1 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_hydro_4 PF02056.16 RJW66356.1 - 0.11 12.1 0.1 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Pescadillo_N PF06732.11 RJW66357.1 - 6.2e-89 298.2 0.1 1.1e-88 297.3 0.1 1.3 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 RJW66357.1 - 3.8e-07 30.4 0.0 7.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Sterile PF03015.19 RJW66357.1 - 0.15 12.3 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 Male sterility protein CAP PF00188.26 RJW66358.1 - 6.5e-19 69.0 0.2 1.4e-18 67.9 0.2 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Pam16 PF03656.13 RJW66359.1 - 0.033 14.2 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Pam16 HSF_DNA-bind PF00447.17 RJW66360.1 - 3.3e-24 85.3 0.1 6.7e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding HALZ PF02183.18 RJW66360.1 - 0.06 13.6 1.1 0.16 12.2 1.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper HAP1_N PF04849.13 RJW66360.1 - 0.087 12.0 0.2 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Ldh_1_C PF02866.18 RJW66361.1 - 1.4e-05 25.1 0.0 1.5e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain PTPlike_phytase PF14566.6 RJW66362.1 - 1.6e-28 99.8 0.1 2.6e-15 56.9 0.1 4.1 3 1 0 3 3 3 2 Inositol hexakisphosphate PRMT5 PF05185.16 RJW66365.1 - 3.5e-62 209.3 0.0 4.8e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 RJW66365.1 - 4.1e-49 167.1 0.2 5.7e-49 166.6 0.2 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 RJW66365.1 - 1.7e-48 164.8 0.6 2.9e-48 164.1 0.6 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Sin3_corepress PF08295.12 RJW66366.1 - 2.4e-32 110.9 0.8 5.7e-32 109.7 0.8 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 RJW66366.1 - 3e-29 102.6 0.0 2e-28 99.9 0.0 2.5 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 RJW66366.1 - 2.2e-28 98.1 2.1 4.4e-15 55.5 1.5 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat RVT_1 PF00078.27 RJW66366.1 - 0.00064 19.3 0.0 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ASC PF00858.24 RJW66367.1 - 3.9e-09 36.0 0.2 7.9e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Fib_alpha PF08702.10 RJW66367.1 - 0.17 12.1 1.6 3.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.22 RJW66368.1 - 1.9e-27 94.9 0.3 4.1e-13 49.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW66368.1 - 3.5e-09 36.7 0.1 4.5e-06 26.7 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RJW66368.1 - 0.0098 15.9 0.1 5.8 7.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Adaptin_N PF01602.20 RJW66369.1 - 1.8e-82 277.6 5.8 2.6e-82 277.1 5.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region AP3D1 PF06375.11 RJW66369.1 - 3.4e-38 131.4 3.0 3.4e-38 131.4 3.0 2.1 2 1 0 2 2 2 1 AP-3 complex subunit delta-1 Cnd1 PF12717.7 RJW66369.1 - 1e-13 51.6 0.2 2.6e-08 34.1 0.0 2.7 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RJW66369.1 - 2.5e-05 24.6 0.0 0.061 13.7 0.0 3.6 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 RJW66369.1 - 2.5e-05 24.1 0.0 0.7 10.3 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat RTP1_C1 PF10363.9 RJW66369.1 - 0.0017 18.5 2.8 1.8 8.8 0.4 3.0 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 RJW66369.1 - 0.096 13.1 0.1 11 6.5 0.1 3.2 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain V-ATPase_H_C PF11698.8 RJW66369.1 - 0.16 12.1 0.3 4.4 7.5 0.1 2.8 1 1 1 2 2 2 0 V-ATPase subunit H SAM_2 PF07647.17 RJW66370.1 - 3.9e-20 71.7 0.0 1.4e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RJW66370.1 - 6.5e-19 68.1 0.0 2.1e-14 53.7 0.1 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 RJW66370.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.17 RJW66370.1 - 0.19 11.5 0.0 0.51 10.1 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain PAZ PF02170.22 RJW66372.1 - 7.8e-32 109.9 0.0 1.5e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Dicer_dimer PF03368.14 RJW66372.1 - 7e-22 77.4 0.0 2.1e-21 75.9 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonuclease_3 PF00636.26 RJW66372.1 - 1.4e-10 41.7 0.0 5e-10 39.9 0.0 2.1 1 0 0 1 1 1 1 Ribonuclease III domain Helicase_C PF00271.31 RJW66372.1 - 0.0001 22.6 0.0 0.00028 21.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PQ-loop PF04193.14 RJW66374.1 - 3.7e-37 125.9 13.8 2.4e-18 65.6 1.1 2.8 2 0 0 2 2 2 2 PQ loop repeat Spec3 PF15795.5 RJW66374.1 - 0.039 14.5 0.3 0.039 14.5 0.3 2.9 2 1 0 2 2 2 0 Ectodermal ciliogenesis protein RRM_1 PF00076.22 RJW66375.1 - 2.2e-36 123.5 0.3 2e-17 62.7 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LSM_int_assoc PF16605.5 RJW66375.1 - 0.00044 20.3 3.2 0.0015 18.6 3.2 1.9 1 1 0 1 1 1 1 LSM-interacting associated unstructured RRM_occluded PF16842.5 RJW66375.1 - 0.008 16.0 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif Mad3_BUB1_I PF08311.12 RJW66375.1 - 0.0088 16.0 2.2 10 6.1 0.0 4.7 5 0 0 5 5 5 1 Mad3/BUB1 homology region 1 RRM_5 PF13893.6 RJW66375.1 - 0.016 14.8 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_14 PF13428.6 RJW66375.1 - 0.02 15.7 9.7 1.8 9.6 0.9 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Lsm_interact PF05391.11 RJW66375.1 - 0.34 10.5 9.7 0.013 15.0 3.5 1.9 2 0 0 2 2 2 0 Lsm interaction motif Collagen PF01391.18 RJW66377.1 - 8.2e-05 22.3 25.1 0.00012 21.7 16.5 5.3 5 0 0 5 5 5 2 Collagen triple helix repeat (20 copies) TBP PF00352.21 RJW66379.1 - 2e-35 120.6 0.1 2.5e-19 69.0 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) TEBP_beta PF07404.11 RJW66379.1 - 0.37 10.1 1.8 0.58 9.5 1.8 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Kinesin PF00225.23 RJW66380.1 - 4.2e-91 305.3 0.0 1.3e-90 303.7 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW66380.1 - 2.2e-19 69.9 0.0 5.1e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 RJW66380.1 - 0.00072 19.8 0.6 0.0031 17.7 0.6 2.2 1 1 0 1 1 1 1 Kinesin-associated betaPIX_CC PF16523.5 RJW66380.1 - 0.03 14.1 2.6 0.065 13.1 2.6 1.5 1 0 0 1 1 1 0 betaPIX coiled coil GLYCAM-1 PF05242.11 RJW66380.1 - 0.4 10.8 2.1 12 6.1 0.2 2.5 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DUF4164 PF13747.6 RJW66380.1 - 1.3 9.4 3.9 0.41 11.0 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) RVT_1 PF00078.27 RJW66381.1 - 2.7e-45 154.6 0.0 4.8e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW66381.1 - 0.0001 21.9 0.7 0.00022 20.8 0.7 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sas6_CC PF18594.1 RJW66383.1 - 0.31 10.9 10.0 2.8 7.8 0.0 3.7 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain Innexin PF00876.18 RJW66384.1 - 3.9e-107 358.6 14.2 4.7e-107 358.3 14.2 1.1 1 0 0 1 1 1 1 Innexin BACK PF07707.15 RJW66385.1 - 6.1e-17 61.6 1.1 5.1e-16 58.6 0.2 2.5 2 1 1 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 RJW66385.1 - 7.9e-09 35.7 0.2 1.5e-08 34.8 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain I-set PF07679.16 RJW66386.1 - 1.3e-06 28.4 0.1 3.1e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW66386.1 - 1.2e-05 25.8 0.2 5.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RJW66386.1 - 3e-05 24.1 0.1 0.0001 22.4 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RJW66386.1 - 3e-05 24.2 1.2 0.00011 22.4 0.2 2.5 3 1 0 3 3 3 1 Immunoglobulin domain Innexin PF00876.18 RJW66387.1 - 7.3e-51 173.5 3.2 8.9e-51 173.2 3.2 1.1 1 0 0 1 1 1 1 Innexin COesterase PF00135.28 RJW66389.1 - 1.8e-57 195.4 0.0 4e-57 194.3 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RJW66389.1 - 0.00067 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold TPPK_C PF12555.8 RJW66389.1 - 0.05 13.7 1.7 3.5 7.7 0.3 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Bromodomain PF00439.25 RJW66390.1 - 2.7e-73 242.1 7.6 1e-18 67.2 0.1 5.5 6 0 0 6 6 6 4 Bromodomain BET PF17035.5 RJW66390.1 - 4.1e-54 180.6 6.5 7.5e-27 93.3 0.4 2.8 2 0 0 2 2 2 2 Bromodomain extra-terminal - transcription regulation Sec3_C_2 PF15278.6 RJW66390.1 - 0.015 15.6 3.1 3.1 8.2 0.1 3.0 2 0 0 2 2 2 0 Sec3 exocyst complex subunit DUF424 PF04242.13 RJW66390.1 - 0.035 14.3 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF424) Dna2 PF08696.11 RJW66390.1 - 0.061 13.1 11.0 0.34 10.7 0.0 3.3 4 0 0 4 4 4 0 DNA replication factor Dna2 LXG PF04740.12 RJW66390.1 - 0.46 10.2 4.6 1.7 8.3 0.4 2.7 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF3825 PF12873.7 RJW66390.1 - 0.48 9.8 4.8 1.2 8.6 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3825) DUF16 PF01519.16 RJW66390.1 - 1.2 9.6 6.6 9.1 6.8 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 RJW66390.1 - 1.5 8.8 6.0 13 5.9 0.5 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HAP1_N PF04849.13 RJW66391.1 - 0.0078 15.5 13.5 0.011 15.0 13.5 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DcrB PF08786.11 RJW66391.1 - 0.53 10.4 5.5 0.28 11.3 0.6 2.0 1 1 1 2 2 2 0 DcrB DUF1319 PF07028.11 RJW66391.1 - 0.71 10.1 6.8 1.1 9.5 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Sec34 PF04136.15 RJW66391.1 - 1.5 8.7 11.9 2.9 7.8 2.5 2.1 1 1 1 2 2 2 0 Sec34-like family SlyX PF04102.12 RJW66391.1 - 9 7.0 11.4 24 5.6 0.9 2.8 2 1 0 2 2 2 0 SlyX Syntaxin-6_N PF09177.11 RJW66391.1 - 9.1 6.9 9.8 14 6.3 2.2 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RVT_1 PF00078.27 RJW66392.1 - 9.9e-09 35.0 0.1 1.4e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 RJW66395.1 - 3.7e-48 164.2 30.3 1.4e-47 162.4 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 RJW66395.1 - 0.31 10.7 4.1 3.5 7.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Dynamin_M PF01031.20 RJW66396.1 - 1.4e-93 313.2 0.6 4.8e-93 311.5 0.0 2.1 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 RJW66396.1 - 2.3e-56 190.4 0.0 5e-56 189.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 RJW66396.1 - 1.7e-08 34.5 0.4 5.4e-08 32.9 0.4 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 RJW66396.1 - 1.8e-05 25.2 0.0 3.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 RJW66396.1 - 0.00023 21.2 0.0 0.00084 19.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RJW66396.1 - 0.014 15.8 0.1 6.5 7.1 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain PH_11 PF15413.6 RJW66396.1 - 0.079 13.4 0.4 0.45 10.9 0.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain RsgA_GTPase PF03193.16 RJW66396.1 - 0.14 12.0 0.0 3.2 7.6 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase CRAL_TRIO PF00650.20 RJW66400.1 - 3.2e-19 69.2 0.1 5e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain PolyA_pol_RNAbd PF12627.7 RJW66400.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.8 1 1 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A CRAL_TRIO_2 PF13716.6 RJW66400.1 - 0.054 13.7 0.4 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain MA3 PF02847.17 RJW66401.1 - 2.2e-06 27.6 0.1 0.00064 19.7 0.0 2.9 3 0 0 3 3 3 2 MA3 domain MIF4G PF02854.19 RJW66401.1 - 1.5e-05 24.8 0.2 2.9e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 MIF4G domain RNA_pol_Rpc4 PF05132.14 RJW66401.1 - 0.00029 21.3 0.0 0.00029 21.3 0.0 2.4 3 1 1 4 4 4 1 RNA polymerase III RPC4 PolyA_pol_RNAbd PF12627.7 RJW66401.1 - 0.12 12.2 0.3 0.28 11.0 0.3 1.6 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Pkinase PF00069.25 RJW66402.1 - 4.6e-16 59.0 0.1 6.2e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66402.1 - 2.1e-08 33.8 0.1 2.9e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Use1 PF09753.9 RJW66404.1 - 1.2e-69 234.8 0.6 1.5e-69 234.5 0.6 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 MCU PF04678.13 RJW66404.1 - 0.033 14.3 2.2 0.079 13.1 2.2 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter UPF0242 PF06785.11 RJW66404.1 - 3.6 7.7 10.5 9.1 6.3 10.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS-augmin3 PF14932.6 RJW66404.1 - 6.7 6.2 12.2 2.5 7.6 9.0 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 tRNA-synt_2b PF00587.25 RJW66405.1 - 1e-39 136.4 0.1 1.7e-39 135.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 RJW66405.1 - 1.2e-12 48.0 0.3 4.4e-12 46.2 0.3 2.0 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 RJW66406.1 - 1.8e-31 109.5 0.0 5.8e-31 107.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66406.1 - 3.1e-07 29.9 0.0 6.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW66406.1 - 0.03 14.3 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 RJW66406.1 - 0.21 11.2 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-C2H2_4 PF13894.6 RJW66407.1 - 8.4e-15 54.2 58.3 0.0014 19.3 0.5 9.4 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW66407.1 - 1.3e-12 47.4 49.4 0.0022 18.3 0.8 9.0 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 RJW66407.1 - 6.7e-06 26.4 18.9 0.042 14.2 0.2 6.9 5 1 3 8 8 8 1 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 RJW66407.1 - 4.5e-05 23.7 6.5 0.00088 19.6 1.1 8.3 9 0 0 9 9 9 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW66407.1 - 0.0012 18.8 39.7 0.013 15.5 3.3 7.3 7 0 0 7 7 7 3 C2H2-type zinc finger zf-Di19 PF05605.12 RJW66407.1 - 0.0024 18.1 3.2 0.0024 18.1 3.2 7.2 7 1 0 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 RJW66407.1 - 0.019 15.2 39.2 0.041 14.2 0.0 8.5 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 RJW66407.1 - 0.026 14.4 0.4 0.026 14.4 0.4 4.9 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf_PR_Knuckle PF18445.1 RJW66407.1 - 0.076 12.8 6.9 0.47 10.3 6.9 2.5 1 0 0 1 1 1 0 PR zinc knuckle motif zf-met PF12874.7 RJW66407.1 - 0.16 12.4 27.8 0.79 10.2 2.1 6.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Yippee-Mis18 PF03226.14 RJW66407.1 - 0.3 11.3 5.6 23 5.2 0.0 3.6 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly UFD1 PF03152.14 RJW66408.1 - 5.1e-37 127.0 0.1 3e-36 124.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 RJW66408.1 - 0.0094 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 ATHILA PF03078.15 RJW66408.1 - 0.04 12.7 0.1 0.053 12.3 0.1 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family SelR PF01641.18 RJW66409.1 - 2.5e-35 121.2 0.3 3.2e-30 104.7 0.1 2.3 2 0 0 2 2 2 2 SelR domain zinc_ribbon_10 PF10058.9 RJW66409.1 - 0.079 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein RVT_1 PF00078.27 RJW66411.1 - 1.6e-07 31.0 0.0 2.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Corona_NS4 PF03905.13 RJW66411.1 - 0.16 12.0 0.0 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 Coronavirus non-structural protein NS4 RPAP1_N PF08621.10 RJW66411.1 - 0.65 9.8 0.0 0.65 9.8 0.0 2.6 3 0 0 3 3 3 0 RPAP1-like, N-terminal HSP20 PF00011.21 RJW66414.1 - 2.4e-29 101.5 0.6 4.1e-15 55.8 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RJW66414.1 - 3.9e-07 29.5 0.0 1.3e-05 24.7 0.0 2.5 2 1 0 2 2 2 1 HSP20-like domain found in ArsA EF_TS PF00889.19 RJW66415.1 - 3e-25 89.1 0.0 1.4e-21 77.1 0.0 2.2 2 0 0 2 2 2 2 Elongation factor TS HSP20 PF00011.21 RJW66416.1 - 3.1e-28 97.9 0.2 2.1e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RJW66416.1 - 3.7e-06 26.4 0.0 0.00051 19.6 0.0 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Inhibitor_I53 PF11714.8 RJW66418.1 - 0.083 13.1 0.6 0.083 13.1 0.6 3.0 2 1 1 3 3 3 0 Thrombin inhibitor Madanin Imm51 PF15595.6 RJW66418.1 - 0.26 11.3 2.4 21 5.1 0.2 2.6 2 0 0 2 2 2 0 Immunity protein 51 Inhibitor_I69 PF13734.6 RJW66418.1 - 1.2 9.6 5.4 71 3.9 0.3 3.3 3 0 0 3 3 3 0 Spi protease inhibitor Sel1 PF08238.12 RJW66419.1 - 0.00013 22.5 0.1 0.26 12.0 0.0 3.2 4 0 0 4 4 4 2 Sel1 repeat HisK_N PF09385.10 RJW66419.1 - 0.068 13.1 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase N terminal Tcp11 PF05794.13 RJW66420.1 - 2.3e-98 330.2 0.0 2.8e-98 329.9 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 hEGF PF12661.7 RJW66421.1 - 0.017 15.7 3.7 0.017 15.7 3.7 8.4 8 0 0 8 8 8 0 Human growth factor-like EGF DUF5316 PF17247.2 RJW66421.1 - 4.4 7.4 7.4 19 5.3 1.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5316) EGF_CA PF07645.15 RJW66421.1 - 5.2 7.4 27.4 9.4 6.5 4.2 5.7 4 0 0 4 4 4 0 Calcium-binding EGF domain TSP_1 PF00090.19 RJW66421.1 - 6.1 7.2 39.0 0.074 13.3 6.2 3.8 4 0 0 4 4 4 0 Thrombospondin type 1 domain HSP20 PF00011.21 RJW66422.1 - 4.6e-27 94.1 0.8 2.6e-14 53.2 0.0 2.8 3 0 0 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RJW66422.1 - 1.2e-06 28.0 0.0 8.2e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 HSP20-like domain found in ArsA FAD_binding_6 PF00970.24 RJW66423.1 - 1.6e-12 47.6 0.0 1.5e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 RJW66423.1 - 1.7e-10 40.9 0.0 3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 RJW66423.1 - 8.5e-06 26.4 0.0 2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain TTL PF03133.15 RJW66424.1 - 2.7e-52 177.7 0.3 3.9e-52 177.2 0.3 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RJW66424.1 - 1.1e-07 31.4 0.0 1.7e-05 24.2 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RJW66424.1 - 0.0021 17.4 0.0 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp BBS2_C PF14782.6 RJW66426.1 - 8.5e-88 295.0 1.0 3.1e-86 289.8 0.3 2.8 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 RJW66426.1 - 5.8e-33 113.2 0.1 5.2e-32 110.1 0.0 2.4 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 RJW66426.1 - 1.1e-14 54.1 0.0 3.7e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal BBS1 PF14779.6 RJW66426.1 - 0.054 12.9 0.0 0.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 DUF5611 PF18446.1 RJW66426.1 - 0.11 13.4 0.1 0.26 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5611) VCBS PF13517.6 RJW66426.1 - 0.13 12.9 0.2 3.1 8.5 0.0 2.6 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-C2H2_jaz PF12171.8 RJW66427.1 - 0.0006 20.0 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF5531 PF17671.1 RJW66427.1 - 0.044 13.7 0.5 0.06 13.2 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5531) zf-met PF12874.7 RJW66427.1 - 0.056 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 RJW66427.1 - 0.35 11.4 0.3 0.35 11.4 0.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 RJW66432.1 - 2.3e-10 40.3 27.8 0.0021 18.4 3.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66432.1 - 2.1e-07 31.2 23.5 0.011 16.5 3.7 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW66432.1 - 2e-05 24.8 19.9 0.00063 20.1 0.6 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW66432.1 - 0.0013 19.0 11.7 0.64 10.4 0.6 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW66432.1 - 0.0026 17.7 19.9 0.02 14.9 2.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-AN1 PF01428.16 RJW66432.1 - 0.028 14.6 12.3 0.26 11.5 1.7 3.6 2 1 0 3 3 3 0 AN1-like Zinc finger DUF4379 PF14311.6 RJW66432.1 - 0.064 13.6 0.9 0.064 13.6 0.9 2.4 3 0 0 3 3 3 0 Probable Zinc-ribbon domain zf-met PF12874.7 RJW66432.1 - 0.19 12.1 11.0 0.69 10.4 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RJW66432.1 - 0.34 11.2 8.3 0.35 11.2 2.5 2.6 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Endonuclease_7 PF02945.15 RJW66432.1 - 0.94 9.4 7.2 2.4 8.1 7.2 1.7 1 0 0 1 1 1 0 Recombination endonuclease VII C1_4 PF07975.12 RJW66432.1 - 1.8 8.9 7.2 9.9 6.5 3.1 2.7 1 1 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_11 PF16622.5 RJW66432.1 - 4 7.3 11.1 0.58 10.0 1.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type MFS_1 PF07690.16 RJW66433.1 - 2.3e-33 115.6 27.8 3e-33 115.2 27.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RJW66433.1 - 5.8e-08 32.0 6.1 5.8e-08 32.0 6.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3040 PF11239.8 RJW66433.1 - 9.7 6.5 8.4 4.6 7.6 2.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) SH3_2 PF07653.17 RJW66434.1 - 1.4e-12 47.1 0.1 3.1e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RJW66434.1 - 8.2e-10 38.4 0.2 1.8e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RJW66434.1 - 1.3e-09 37.5 0.3 2.6e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 SH3 domain RhoGEF PF00621.20 RJW66434.1 - 2.3e-08 34.5 0.2 4.1e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain FHA PF00498.26 RJW66435.1 - 7.5e-14 51.8 0.0 2.2e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 FHA domain Dicer_dimer PF03368.14 RJW66435.1 - 5.3e-05 23.3 0.0 0.00018 21.6 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.26 RJW66435.1 - 0.00062 20.4 0.4 0.02 15.6 0.0 3.1 2 0 0 2 2 2 1 Double-stranded RNA binding motif ABC_tran_CTD PF16326.5 RJW66435.1 - 0.01 16.0 1.8 0.034 14.4 1.8 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain CCDC-167 PF15188.6 RJW66435.1 - 0.013 15.8 2.3 0.039 14.3 2.3 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 MitMem_reg PF13012.6 RJW66437.1 - 3.7e-23 82.1 0.2 5.9e-23 81.4 0.2 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 RJW66437.1 - 1.7e-16 60.2 0.0 3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HECT PF00632.25 RJW66440.1 - 3.2e-96 322.4 0.3 5.1e-96 321.8 0.3 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 RJW66440.1 - 5.1e-44 148.0 20.8 1.3e-12 47.6 1.9 4.9 5 0 0 5 5 5 4 WW domain MBD PF01429.19 RJW66440.1 - 0.3 10.8 6.2 8.2 6.2 0.1 4.5 5 0 0 5 5 5 0 Methyl-CpG binding domain PI_PP_I PF18363.1 RJW66440.1 - 1 9.6 3.1 2.2 8.5 0.1 3.0 4 0 0 4 4 4 0 Phosphoinositide phosphatase insertion domain WW PF00397.26 RJW66441.1 - 1.5e-08 34.5 0.1 3.7e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 WW domain EGF_2 PF07974.13 RJW66442.1 - 0.004 17.5 7.5 0.004 17.5 7.5 5.5 4 1 1 5 5 5 2 EGF-like domain Laminin_EGF PF00053.24 RJW66442.1 - 0.71 10.1 45.9 0.77 9.9 5.5 5.3 3 1 2 5 5 5 0 Laminin EGF domain WD40 PF00400.32 RJW66443.1 - 9.3e-60 197.2 18.6 2.2e-07 31.5 0.0 8.7 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW66443.1 - 2.2e-18 66.3 1.4 0.017 15.4 0.0 7.3 3 2 3 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RJW66443.1 - 1.2e-06 28.1 0.0 0.76 9.0 0.0 4.8 3 2 2 5 5 5 2 WD40-like domain Nup160 PF11715.8 RJW66443.1 - 2.8e-06 26.3 5.6 0.0079 14.9 0.2 4.5 1 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RJW66443.1 - 4.4e-06 25.9 1.8 0.22 10.4 0.1 4.7 3 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SMC_ScpA PF02616.14 RJW66443.1 - 0.074 12.9 0.0 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 Segregation and condensation protein ScpA TFIIS_C PF01096.18 RJW66444.1 - 3.3e-13 49.2 6.2 1.1e-12 47.6 2.4 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 RJW66444.1 - 1.3e-09 37.8 4.9 1.5e-08 34.4 0.7 2.6 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Ogr_Delta PF04606.12 RJW66444.1 - 0.0021 18.0 1.1 0.0021 18.0 1.1 2.2 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger CpXC PF14353.6 RJW66444.1 - 0.0032 17.5 5.7 0.19 11.8 0.4 2.1 1 1 0 2 2 2 2 CpXC protein Gmx_para_CXXCG PF09535.10 RJW66444.1 - 0.016 14.5 0.2 0.02 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) DUF3716 PF12511.8 RJW66444.1 - 0.022 14.8 4.8 0.75 9.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) TF_Zn_Ribbon PF08271.12 RJW66444.1 - 0.16 11.5 4.1 0.39 10.3 0.3 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding DUF3268 PF11672.8 RJW66444.1 - 0.23 11.8 5.9 0.48 10.8 0.9 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain Cytochrom_NNT PF03264.14 RJW66444.1 - 1.1 9.0 6.7 0.17 11.6 1.2 1.9 1 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Rubredoxin_2 PF18073.1 RJW66444.1 - 2.8 7.7 10.3 4.4 7.1 0.3 2.7 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-CCCH PF00642.24 RJW66445.1 - 4.2e-16 58.4 11.8 4.7e-08 32.7 0.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RJW66445.1 - 4.7e-10 39.0 12.2 8e-07 28.7 1.1 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RJW66445.1 - 1.8e-08 34.2 14.1 3.2e-06 27.0 2.3 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 RJW66445.1 - 6e-05 23.4 14.7 0.024 15.1 2.0 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 RJW66445.1 - 0.0091 16.7 7.0 0.37 11.5 0.5 2.4 1 1 1 2 2 2 2 Torus domain ESCRT-II PF05871.12 RJW66446.1 - 1.5e-49 167.8 0.1 1.9e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Arc PF03869.14 RJW66446.1 - 0.016 15.0 0.1 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Arc-like DNA binding domain PGAP1 PF07819.13 RJW66447.1 - 6.3e-45 153.7 0.0 9.3e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein EF1G PF00647.19 RJW66451.1 - 3.3e-48 162.2 0.0 6.8e-48 161.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 RJW66451.1 - 6.2e-13 48.8 0.0 1.5e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RJW66451.1 - 1.3e-11 44.7 0.0 5.1e-11 42.7 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RJW66451.1 - 9.5e-10 38.6 0.0 2.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RJW66451.1 - 5.8e-08 32.7 0.0 1.6e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RJW66451.1 - 1.8e-07 31.4 0.0 1.2e-06 28.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RJW66451.1 - 0.00024 21.3 0.1 0.0047 17.2 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 RJW66451.1 - 0.0024 17.6 0.0 0.0078 16.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 RJW66451.1 - 0.036 14.4 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain NARP1 PF12569.8 RJW66451.1 - 0.66 8.8 3.4 0.98 8.3 3.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 START PF01852.19 RJW66452.1 - 1.4e-14 54.0 0.7 8.7e-14 51.4 0.7 2.1 1 1 0 1 1 1 1 START domain PH_8 PF15409.6 RJW66452.1 - 1.4e-09 38.1 0.1 2.7e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 RJW66452.1 - 6.9e-09 36.2 0.0 1.7e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RJW66452.1 - 2e-05 24.9 0.2 0.0019 18.6 0.2 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain Copine PF07002.16 RJW66453.1 - 0.055 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Copine MRG PF05712.13 RJW66454.1 - 2.6e-11 43.2 0.0 1.2e-10 41.1 0.0 2.1 2 1 0 2 2 2 1 MRG Tudor-knot PF11717.8 RJW66454.1 - 0.0006 19.6 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Drf_DAD PF06345.11 RJW66455.1 - 0.25 11.4 0.7 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 DRF Autoregulatory Domain BTB PF00651.31 RJW66456.1 - 3.1e-18 66.0 0.1 7.8e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain PHR PF08005.12 RJW66456.1 - 6.8e-12 46.3 0.1 2.3e-05 25.1 0.0 3.5 3 0 0 3 3 3 2 PHR domain BACK PF07707.15 RJW66456.1 - 5.7e-08 32.8 0.0 1.3e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 BTB And C-terminal Kelch DUF3449 PF11931.8 RJW66458.1 - 1.1e-73 247.0 0.1 2.4e-73 245.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 RJW66458.1 - 8.8e-26 89.3 1.2 8.8e-26 89.3 1.2 1.9 2 0 0 2 2 2 1 Telomere stability C-terminal SF3A3 PF16837.5 RJW66458.1 - 3.4e-23 82.0 1.2 3.4e-23 82.0 1.2 2.4 2 1 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 RJW66458.1 - 1.3e-14 53.7 1.4 1.3e-14 53.7 1.4 2.5 3 0 0 3 3 3 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 RJW66458.1 - 0.0019 18.5 0.1 0.0036 17.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PI-PLC-C1 PF16670.5 RJW66458.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent DNA_pol_E_B PF04042.16 RJW66461.1 - 5.1e-26 91.3 0.0 8.1e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B UreE_N PF02814.15 RJW66461.1 - 0.00021 20.8 0.4 0.00043 19.8 0.4 1.4 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain ASC PF00858.24 RJW66462.1 - 6.9e-50 170.3 3.8 3.7e-49 167.9 3.8 1.8 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel NUFIP1 PF10453.9 RJW66464.1 - 3.7e-06 26.7 0.2 2.5e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) adh_short PF00106.25 RJW66465.1 - 5.8e-19 68.3 0.0 1e-12 48.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RJW66465.1 - 9.7e-15 54.7 0.0 1.3e-09 38.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW66465.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Tubulin PF00091.25 RJW66467.1 - 6.6e-62 209.2 0.0 9.3e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW66467.1 - 1.5e-41 141.5 0.0 2.5e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Homeodomain PF00046.29 RJW66468.1 - 4.8e-17 61.5 3.5 9.4e-17 60.6 3.5 1.5 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 RJW66468.1 - 1e-15 57.7 31.8 7.5e-12 45.3 12.1 3.4 4 0 0 4 4 4 2 LIM domain Homeobox_KN PF05920.11 RJW66468.1 - 8.9e-05 22.3 0.1 0.00019 21.2 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-C6H2 PF15801.5 RJW66471.1 - 0.19 12.1 3.5 0.51 10.7 3.5 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Anti-TRAP PF15777.5 RJW66471.1 - 0.26 11.3 4.9 0.54 10.3 4.9 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein ATP-grasp_2 PF08442.10 RJW66472.1 - 1.6e-53 181.3 0.0 2.4e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 RJW66472.1 - 3.2e-21 75.7 0.8 6.3e-21 74.8 0.8 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 RJW66472.1 - 0.00048 19.6 0.1 0.0018 17.8 0.1 2.0 1 1 0 1 1 1 1 ATP-grasp domain OppC_N PF12911.7 RJW66473.1 - 0.01 15.8 0.6 0.019 14.9 0.6 1.4 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C ASFV_J13L PF05568.11 RJW66473.1 - 0.17 11.6 0.1 0.25 11.1 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Spore_III_AF PF09581.10 RJW66473.1 - 0.18 11.8 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Copine PF07002.16 RJW66474.1 - 7.9e-49 166.0 0.0 1.1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 RJW66474.1 - 6.2e-08 32.9 0.0 6.6e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 C2 domain vWA-TerF-like PF10138.9 RJW66474.1 - 7.1e-05 23.0 0.1 0.0008 19.6 0.0 2.1 1 1 0 2 2 2 1 vWA found in TerF C terminus CheX PF13690.6 RJW66474.1 - 0.11 12.7 0.0 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase CheX SUZ PF12752.7 RJW66475.1 - 4e-12 46.7 1.4 1.1e-11 45.3 0.0 2.4 2 0 0 2 2 2 1 SUZ domain Tubulin_C PF03953.17 RJW66478.1 - 6.9e-52 174.9 0.0 9.6e-52 174.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain V-set PF07686.17 RJW66480.1 - 8.1e-09 35.6 1.3 5.5e-07 29.7 0.1 3.0 2 1 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 RJW66480.1 - 1e-08 35.1 0.1 2.5e-05 24.2 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW66480.1 - 7e-08 33.0 3.1 0.001 19.6 0.0 3.9 2 2 1 3 3 3 2 Immunoglobulin domain ig PF00047.25 RJW66480.1 - 9.7e-07 28.9 5.5 7.9e-05 22.8 0.2 4.1 3 1 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 RJW66480.1 - 1.1e-05 25.7 0.2 0.26 11.6 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 RJW66480.1 - 0.0094 16.0 0.2 0.025 14.7 0.2 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain FixO PF02433.15 RJW66480.1 - 0.013 15.0 0.0 0.073 12.5 0.0 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO Sulfotransfer_3 PF13469.6 RJW66482.1 - 5.8e-13 49.7 0.0 1.2e-12 48.7 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Histone PF00125.24 RJW66486.1 - 1e-11 45.3 1.5 1e-11 45.3 1.5 2.3 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 Sulfotransfer_3 PF13469.6 RJW66487.1 - 5.7e-34 118.4 0.0 1.6e-33 116.9 0.0 1.7 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RJW66487.1 - 5.6e-07 29.3 0.0 2.9e-05 23.7 0.0 2.6 1 1 0 1 1 1 1 Sulfotransferase domain Ribosomal_L37e PF01907.19 RJW66488.1 - 6.9 6.9 14.7 2.4 8.4 7.5 2.4 1 1 1 2 2 2 0 Ribosomal protein L37e Ig_3 PF13927.6 RJW66489.1 - 6.1e-14 52.4 0.5 8.6e-06 26.3 0.0 5.0 5 1 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 RJW66489.1 - 6e-07 29.4 0.0 0.00075 19.5 0.0 4.0 3 1 0 3 3 3 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW66489.1 - 2e-06 28.0 2.5 11 6.4 0.2 5.9 6 2 0 6 6 6 3 Immunoglobulin domain ig PF00047.25 RJW66489.1 - 0.0011 19.1 1.3 6.5 7.0 0.0 4.9 4 1 0 4 4 4 1 Immunoglobulin domain C2-set_2 PF08205.12 RJW66489.1 - 0.0099 15.9 0.6 6.7 6.9 0.1 3.0 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RJW66489.1 - 0.031 14.5 0.0 11 6.2 0.0 3.9 4 0 0 4 4 4 0 Immunoglobulin V-set domain Sulfotransfer_3 PF13469.6 RJW66490.1 - 1.8e-35 123.3 0.0 9.2e-35 121.0 0.0 2.0 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RJW66490.1 - 5.1e-10 39.3 0.2 3.9e-09 36.4 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain PMT2_N PF17987.1 RJW66490.1 - 0.087 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal RVT_1 PF00078.27 RJW66491.1 - 8.7e-05 22.1 0.0 0.11 11.9 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Tubulin PF00091.25 RJW66492.1 - 4.2e-65 219.6 0.0 6e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW66492.1 - 2.2e-51 173.3 0.0 4e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW66492.1 - 0.0045 16.7 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain TSP_1 PF00090.19 RJW66493.1 - 1.9e-09 37.6 5.7 6.3e-09 35.9 5.7 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain EGF PF00008.27 RJW66493.1 - 4.6e-07 30.0 53.7 0.00036 20.8 5.9 7.3 6 1 0 6 6 6 4 EGF-like domain hEGF PF12661.7 RJW66493.1 - 2.2e-05 24.9 42.1 0.0014 19.2 2.2 7.7 6 2 0 6 6 6 3 Human growth factor-like EGF EGF_2 PF07974.13 RJW66493.1 - 0.052 13.9 0.5 0.052 13.9 0.5 7.2 6 2 1 7 7 7 0 EGF-like domain Colipase_C PF02740.14 RJW66493.1 - 0.62 10.3 0.1 0.62 10.3 0.1 4.4 5 0 0 5 5 5 0 Colipase, C-terminal domain FXa_inhibition PF14670.6 RJW66493.1 - 2.4 8.5 36.1 2 8.8 6.6 5.2 5 0 0 5 5 5 0 Coagulation Factor Xa inhibitory site IQ PF00612.27 RJW66494.1 - 1.2e-05 24.7 0.9 2.2e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif Tubulin PF00091.25 RJW66495.1 - 1e-64 218.4 0.0 1.6e-64 217.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW66495.1 - 3.3e-51 172.7 0.0 6.7e-51 171.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW66495.1 - 0.0057 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain TcpQ PF10671.9 RJW66495.1 - 0.17 12.0 0.1 0.5 10.5 0.1 1.8 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q CTP_transf_1 PF01148.20 RJW66496.1 - 1.9e-75 254.1 23.8 2.4e-75 253.8 23.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Filamin PF00630.19 RJW66497.1 - 2e-06 28.5 0.0 2.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat TPR_MLP1_2 PF07926.12 RJW66497.1 - 0.0023 18.0 2.2 0.0025 17.8 0.3 1.9 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.6 RJW66497.1 - 0.004 17.5 0.9 0.039 14.3 0.4 2.6 2 1 1 3 3 3 1 Syntaxin-like protein Syntaxin-6_N PF09177.11 RJW66497.1 - 0.0053 17.3 2.2 0.26 11.8 0.7 2.6 1 1 1 2 2 2 1 Syntaxin 6, N-terminal CdvA PF18822.1 RJW66497.1 - 0.14 12.0 1.4 0.7 9.7 0.2 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF3584 PF12128.8 RJW66497.1 - 0.21 9.0 2.5 0.29 8.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 RJW66497.1 - 0.23 11.7 1.8 3 8.0 1.2 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family P4Ha_N PF08336.11 RJW66497.1 - 0.27 11.2 2.8 0.15 12.1 0.6 1.8 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TMPIT PF07851.13 RJW66497.1 - 0.28 10.4 0.8 0.45 9.7 0.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein Jnk-SapK_ap_N PF09744.9 RJW66497.1 - 0.32 11.2 3.5 1.3 9.3 3.3 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CorA PF01544.18 RJW66497.1 - 0.42 9.9 4.2 0.76 9.0 4.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prefoldin PF02996.17 RJW66497.1 - 0.69 9.8 3.7 0.9 9.5 0.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit zf-H2C2_2 PF13465.6 RJW66498.1 - 5.8e-15 55.0 25.6 0.00074 19.8 0.2 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 RJW66498.1 - 1.6e-14 53.5 27.2 6.6e-05 23.1 1.9 5.2 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66498.1 - 4.3e-14 52.0 26.9 0.0033 18.1 1.6 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger BolA PF01722.18 RJW66498.1 - 8.2e-11 42.0 2.4 5.1e-05 23.5 0.0 3.5 2 1 1 3 3 3 2 BolA-like protein zf-met PF12874.7 RJW66498.1 - 2.9e-08 33.8 18.0 0.00013 22.2 0.2 4.8 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RJW66498.1 - 2.8e-07 30.4 21.4 0.0051 16.8 0.3 4.7 5 0 0 5 5 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW66498.1 - 3.2e-06 27.3 13.2 0.0067 16.7 0.6 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 RJW66498.1 - 3.5e-06 27.7 17.1 0.0064 17.2 0.2 4.6 1 1 3 4 4 4 2 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 RJW66498.1 - 9.2e-06 25.7 10.1 0.016 15.3 1.5 3.7 3 1 0 3 3 3 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 RJW66498.1 - 0.0003 20.2 2.3 0.01 15.4 0.6 3.0 3 1 0 3 3 3 1 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 RJW66498.1 - 0.0025 17.7 11.1 0.068 13.1 2.1 3.4 2 1 1 3 3 3 1 SprT-like zinc ribbon domain HypA PF01155.19 RJW66498.1 - 0.0046 16.9 6.6 1.7 8.7 2.7 3.3 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cys_rich_CPXG PF14255.6 RJW66498.1 - 0.011 15.7 3.7 6.5 6.7 0.2 3.9 3 1 0 3 3 3 0 Cysteine-rich CPXCG CpXC PF14353.6 RJW66498.1 - 0.012 15.7 8.4 3.1 7.9 1.3 3.7 1 1 2 3 3 3 0 CpXC protein zinc_ribbon_4 PF13717.6 RJW66498.1 - 0.017 15.0 6.9 16 5.5 0.2 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 RJW66498.1 - 0.02 14.9 0.5 0.02 14.9 0.5 3.2 2 1 1 3 3 3 0 Transposase zinc-ribbon domain FYVE PF01363.21 RJW66498.1 - 0.022 14.9 3.2 0.022 14.9 3.2 3.4 2 1 1 3 3 3 0 FYVE zinc finger C1_1 PF00130.22 RJW66498.1 - 0.038 13.9 9.5 0.5 10.3 2.4 3.0 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_9 PF16293.5 RJW66498.1 - 0.042 13.7 6.4 0.11 12.4 0.1 3.8 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-trcl PF13451.6 RJW66498.1 - 0.05 13.5 11.3 2.1 8.3 0.2 4.2 4 0 0 4 4 4 0 Probable zinc-ribbon domain Prok-RING_1 PF14446.6 RJW66498.1 - 0.05 13.5 9.7 3.6 7.6 1.2 4.4 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 TerY_C PF15616.6 RJW66498.1 - 0.13 12.3 3.1 0.56 10.3 3.1 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain zf-C2H2_2 PF12756.7 RJW66498.1 - 0.14 12.5 14.8 5.1 7.5 1.6 4.2 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 RJW66498.1 - 0.15 11.6 11.5 5.9 6.6 0.1 4.7 4 1 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Actin_micro PF17003.5 RJW66498.1 - 0.16 11.1 15.9 0.79 8.8 1.4 3.3 1 1 1 3 3 3 0 Putative actin-like family zf-C2H2_11 PF16622.5 RJW66498.1 - 0.2 11.5 14.2 1.6 8.5 0.4 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type ADK_lid PF05191.14 RJW66498.1 - 0.2 11.7 6.8 0.61 10.1 0.5 3.7 3 1 1 4 4 4 0 Adenylate kinase, active site lid A2L_zn_ribbon PF08792.10 RJW66498.1 - 0.36 10.6 10.3 5.6 6.8 0.0 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain DUF3268 PF11672.8 RJW66498.1 - 0.5 10.7 6.4 0.91 9.9 0.5 2.5 1 1 1 2 2 2 0 zinc-finger-containing domain FYDLN_acid PF09538.10 RJW66498.1 - 0.58 10.9 12.4 0.5 11.1 0.9 4.0 3 2 0 3 3 2 0 Protein of unknown function (FYDLN_acid) zf-RRN7 PF11781.8 RJW66498.1 - 0.7 9.6 0.1 0.7 9.6 0.1 2.6 3 0 0 3 3 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 RJW66498.1 - 0.88 9.6 11.3 6 7.0 1.1 3.3 1 1 2 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 RJW66498.1 - 0.97 9.5 15.7 42 4.2 0.2 4.1 2 1 1 3 3 3 0 zinc-ribbons zinc_ribbon_9 PF14369.6 RJW66498.1 - 1.6 9.1 0.0 1.6 9.1 0.0 3.3 5 0 0 5 5 3 0 zinc-ribbon XPA_N PF01286.18 RJW66498.1 - 1.7 8.8 12.3 21 5.2 0.4 4.5 4 0 0 4 4 4 0 XPA protein N-terminal zf-AN1 PF01428.16 RJW66498.1 - 1.7 8.9 12.4 9.4 6.5 0.5 4.4 4 0 0 4 4 4 0 AN1-like Zinc finger TFIIS_C PF01096.18 RJW66498.1 - 2.8 7.9 10.9 9.4 6.2 0.1 4.3 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) DUF2225 PF09986.9 RJW66498.1 - 3 7.5 11.2 1.8 8.2 2.6 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-nanos PF05741.13 RJW66498.1 - 3.4 8.0 12.4 31 4.9 2.8 4.1 2 1 1 3 3 3 0 Nanos RNA binding domain zinc_ribbon_15 PF17032.5 RJW66498.1 - 3.5 8.4 10.6 7.5 7.4 1.8 3.1 1 1 2 3 3 3 0 zinc-ribbon family DUF2256 PF10013.9 RJW66498.1 - 4.9 7.4 15.0 5 7.3 0.6 4.0 5 0 0 5 5 3 0 Uncharacterized protein conserved in bacteria (DUF2256) GFA PF04828.14 RJW66498.1 - 5.7 7.3 10.7 4.2 7.8 1.7 3.6 1 1 3 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme zf-C2HC_2 PF13913.6 RJW66498.1 - 6.1 6.9 16.8 2 8.4 0.7 4.4 5 0 0 5 5 4 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 RJW66498.1 - 6.6 6.9 14.2 4.3 7.5 0.2 3.6 3 1 1 4 4 3 0 KIAA1045 RING finger LIM PF00412.22 RJW66498.1 - 7.8 6.8 11.3 1.6 9.0 1.0 3.4 2 2 0 2 2 2 0 LIM domain P-mevalo_kinase PF04275.14 RJW66500.1 - 1.8e-26 92.3 0.0 2.8e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase Exo_endo_phos_2 PF14529.6 RJW66503.1 - 1e-06 28.6 0.0 3.7e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Actin PF00022.19 RJW66505.1 - 1.2e-151 505.0 0.0 3.7e-151 503.3 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 RJW66507.1 - 1.5e-133 445.4 0.0 5.6e-133 443.5 0.0 1.7 1 1 0 1 1 1 1 Actin SNF PF00209.18 RJW66509.1 - 5.1e-197 655.7 32.7 5.8e-197 655.5 32.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LMBR1 PF04791.16 RJW66509.1 - 2.6e-05 23.3 0.1 6.7e-05 22.0 0.1 1.7 1 0 0 1 1 1 1 LMBR1-like membrane protein Dynein_light PF01221.18 RJW66511.1 - 5.2e-15 55.5 0.0 7.4e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_1 PF00036.32 RJW66511.1 - 6.2e-06 25.4 0.1 0.0068 15.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW66511.1 - 2e-05 25.0 3.2 2.2e-05 24.8 0.6 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW66511.1 - 8.4e-05 22.2 0.4 0.12 12.4 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RJW66511.1 - 0.001 18.8 0.2 0.56 10.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair NOP5NT PF08156.13 RJW66512.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 NOP5NT (NUC127) domain RVT_1 PF00078.27 RJW66514.1 - 2.2e-06 27.3 0.0 4.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Act-Frag_cataly PF09192.10 RJW66514.1 - 0.0094 15.4 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic KH_1 PF00013.29 RJW66515.1 - 1.5e-36 124.0 6.1 1e-13 50.9 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 RJW66515.1 - 4.8e-09 35.9 4.7 1e-05 25.2 0.1 3.1 3 0 0 3 3 3 2 KH domain KH_4 PF13083.6 RJW66515.1 - 0.00066 19.5 1.3 0.091 12.6 0.0 3.0 3 0 0 3 3 3 1 KH domain KH_5 PF13184.6 RJW66515.1 - 0.015 15.4 1.3 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 NusA-like KH domain SH3_10 PF17902.1 RJW66517.1 - 7.7e-07 29.1 0.1 3.8e-06 26.9 0.1 2.3 1 0 0 1 1 1 1 SH3 domain DDE_Tnp_IS1595 PF12762.7 RJW66518.1 - 1.3e-11 44.8 0.7 1.6e-11 44.4 0.5 1.3 1 1 0 1 1 1 1 ISXO2-like transposase domain CBM46 PF18448.1 RJW66518.1 - 0.026 14.8 0.6 0.034 14.4 0.2 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain SNF PF00209.18 RJW66520.1 - 2.6e-197 656.7 34.0 3e-197 656.5 34.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RVT_1 PF00078.27 RJW66522.1 - 7.1e-30 104.2 0.0 1.1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RasGAP PF00616.19 RJW66524.1 - 8.3e-22 77.9 0.0 1.3e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase PP2C PF00481.21 RJW66526.1 - 1.1e-35 123.5 0.0 1.2e-34 120.1 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C GalKase_gal_bdg PF10509.9 RJW66526.1 - 6.7e-20 70.4 0.1 1.4e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 RJW66526.1 - 1.5e-13 50.9 0.0 4.3e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 RJW66526.1 - 8.9e-11 41.9 4.3 8.9e-11 41.9 4.3 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain PP2C_2 PF13672.6 RJW66526.1 - 5e-07 29.6 0.0 1.4e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C G-alpha PF00503.20 RJW66527.1 - 5.2e-73 246.2 6.1 5.3e-71 239.6 2.6 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 RJW66527.1 - 3.3e-14 52.7 0.5 9.8e-11 41.4 0.2 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW66527.1 - 0.0012 18.3 1.5 0.024 14.0 0.3 2.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RJW66527.1 - 0.0023 18.0 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Rad17 PF03215.15 RJW66527.1 - 0.017 15.0 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain GTP_EFTU PF00009.27 RJW66527.1 - 0.018 14.6 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 RJW66527.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 RJW66527.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Proteasome PF00227.26 RJW66529.1 - 1e-28 100.1 0.0 1.3e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Malic_M PF03949.15 RJW66534.1 - 1.9e-90 302.6 0.2 2.3e-90 302.3 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 RJW66534.1 - 1.7e-73 246.3 0.0 2.6e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Ribosomal_S4e PF00900.20 RJW66535.1 - 1.2e-36 124.4 0.2 1.2e-36 124.4 0.2 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 RJW66535.1 - 1.4e-25 88.6 0.2 2.6e-25 87.8 0.2 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 RJW66535.1 - 6.1e-08 32.6 0.3 2e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 RJW66535.1 - 4.1e-07 29.6 0.0 8.4e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 RJW66535.1 - 0.00021 21.2 0.3 0.00071 19.4 0.0 2.1 2 0 0 2 2 2 1 KOW motif Sipho_tail PF05709.11 RJW66535.1 - 0.048 13.1 0.0 0.2 11.0 0.0 1.8 1 1 1 2 2 2 0 Phage tail protein DUF5072 PF16807.5 RJW66535.1 - 0.072 13.2 0.0 0.17 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5072) Vps23_core PF09454.10 RJW66538.1 - 2.3e-19 69.1 0.2 3.7e-19 68.4 0.2 1.3 1 0 0 1 1 1 1 Vps23 core domain UEV PF05743.13 RJW66538.1 - 6.5e-09 35.7 0.0 1.5e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 UEV domain ERM PF00769.19 RJW66538.1 - 0.0016 18.3 6.6 0.0022 17.9 6.6 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family APG6_N PF17675.1 RJW66538.1 - 0.0026 18.3 8.6 0.0043 17.6 8.6 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF812 PF05667.11 RJW66538.1 - 0.0046 15.9 3.0 0.0059 15.6 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FapA PF03961.13 RJW66538.1 - 0.019 13.6 3.3 0.024 13.2 3.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1707 PF08044.11 RJW66538.1 - 0.031 14.3 0.1 0.096 12.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) PhaP_Bmeg PF09602.10 RJW66538.1 - 0.039 13.9 2.5 0.079 12.9 2.5 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) RasGAP_C PF03836.15 RJW66538.1 - 0.04 14.1 3.0 0.076 13.2 3.0 1.4 1 0 0 1 1 1 0 RasGAP C-terminus Jnk-SapK_ap_N PF09744.9 RJW66538.1 - 0.042 14.1 8.7 0.072 13.3 8.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 RJW66538.1 - 0.11 12.0 1.9 0.16 11.5 1.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ISG65-75 PF11727.8 RJW66538.1 - 0.14 11.4 2.0 0.2 10.8 2.0 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Aminopep PF10023.9 RJW66538.1 - 0.16 11.3 1.7 0.19 11.1 1.7 1.1 1 0 0 1 1 1 0 Putative aminopeptidase Tn7_Tnp_TnsA_C PF08721.11 RJW66538.1 - 0.2 12.3 1.0 1.2 9.8 0.2 2.4 1 1 0 2 2 2 0 TnsA endonuclease C terminal DUF3450 PF11932.8 RJW66538.1 - 0.24 10.7 5.8 0.38 10.0 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2203 PF09969.9 RJW66538.1 - 0.32 11.7 1.7 0.64 10.8 1.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Spc24 PF08286.11 RJW66538.1 - 0.47 10.7 4.2 0.83 9.9 4.2 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Tho2 PF11262.8 RJW66538.1 - 0.54 9.4 2.5 0.82 8.8 2.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3987 PF13148.6 RJW66538.1 - 2 7.3 4.6 3 6.8 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) JIP_LZII PF16471.5 RJW66538.1 - 3.7 7.8 11.3 1.2 9.4 8.5 1.6 2 0 0 2 2 1 0 JNK-interacting protein leucine zipper II I-set PF07679.16 RJW66539.1 - 4.7e-271 875.9 0.0 1.9e-19 69.5 0.0 17.5 17 0 0 17 17 17 17 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW66539.1 - 2.9e-196 636.6 16.0 8.7e-15 55.1 0.0 17.5 17 0 0 17 17 17 17 Immunoglobulin domain Ig_2 PF13895.6 RJW66539.1 - 7.2e-103 337.1 8.7 1.1e-09 38.5 0.0 17.4 17 1 0 17 17 17 15 Immunoglobulin domain ig PF00047.25 RJW66539.1 - 2e-96 316.3 6.5 1.5e-09 37.9 0.0 17.2 17 0 0 17 17 17 15 Immunoglobulin domain V-set PF07686.17 RJW66539.1 - 1.5e-26 92.7 17.4 0.34 11.1 0.0 21.0 16 9 1 17 17 17 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 RJW66539.1 - 7.2e-23 80.5 25.7 0.082 13.0 0.0 16.8 18 0 0 18 18 18 6 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RJW66539.1 - 1.9e-11 43.3 1.4 0.61 9.7 0.0 8.4 9 0 0 9 9 9 2 Immunoglobulin domain Spectrin PF00435.21 RJW66539.1 - 5.2e-09 36.5 41.3 7e-05 23.3 1.2 7.3 6 1 1 7 7 6 3 Spectrin repeat C1-set PF07654.15 RJW66539.1 - 1.7e-08 34.7 9.9 1.3 9.4 0.0 10.7 12 0 0 12 12 12 2 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 RJW66539.1 - 1.6e-06 28.1 3.9 7.4 6.7 0.0 7.9 9 0 0 9 9 9 2 Izumo-like Immunoglobulin domain AMP-binding_C_2 PF14535.6 RJW66539.1 - 0.1 12.9 0.2 2.1 8.7 0.0 3.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain AKNA PF12443.8 RJW66539.1 - 0.7 10.6 4.2 0.6 10.8 0.1 2.9 2 0 0 2 2 2 0 AT-hook-containing transcription factor SKA2 PF16740.5 RJW66539.1 - 7.9 6.3 13.7 0.61 9.9 5.0 3.8 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 Tetraspanin PF00335.20 RJW66540.1 - 5.1e-39 134.3 9.3 6.3e-39 134.0 9.3 1.1 1 0 0 1 1 1 1 Tetraspanin family FANCI_HD1 PF14679.6 RJW66540.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 FANCI helical domain 1 Phage_Gp23 PF10669.9 RJW66540.1 - 0.72 10.2 0.0 0.72 10.2 0.0 3.3 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) MgtE PF01769.16 RJW66540.1 - 1.4 9.3 18.6 27 5.2 0.1 3.1 2 1 0 2 2 2 0 Divalent cation transporter GATase_2 PF00310.21 RJW66543.1 - 2e-154 514.4 0.0 3e-154 513.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 RJW66543.1 - 3e-150 500.4 0.3 4.6e-148 493.3 0.1 2.2 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 RJW66543.1 - 8.5e-105 350.2 0.0 6.5e-103 344.0 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 RJW66543.1 - 2.7e-71 239.1 0.6 5.5e-71 238.1 0.6 1.5 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 RJW66543.1 - 4.9e-36 124.5 0.0 2.6e-27 95.8 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 RJW66543.1 - 1.5e-21 76.3 0.1 3.4e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 RJW66543.1 - 1.9e-10 41.1 3.1 1.4e-07 31.9 0.3 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RJW66543.1 - 5.9e-09 36.0 0.7 1.7e-08 34.5 0.1 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RJW66543.1 - 1e-07 31.9 0.2 0.00021 21.0 0.2 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RJW66543.1 - 1.4e-07 31.1 0.0 0.00016 21.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RJW66543.1 - 2.6e-07 30.4 1.9 3.9e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RJW66543.1 - 1e-06 27.7 0.8 1.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 RJW66543.1 - 1.6e-06 27.7 0.1 3.5e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 RJW66543.1 - 1e-05 24.9 0.1 6e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 RJW66543.1 - 3.5e-05 23.1 2.3 4e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 RJW66543.1 - 6.6e-05 23.3 0.1 0.072 13.5 0.0 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 RJW66543.1 - 0.0011 18.2 0.3 0.003 16.8 0.0 1.7 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 RJW66543.1 - 0.0075 15.6 0.5 2.9 7.1 0.1 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 RJW66543.1 - 0.01 14.9 0.4 0.083 11.9 0.5 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase ApbA PF02558.16 RJW66543.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 RJW66543.1 - 0.012 14.6 0.5 0.061 12.4 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 RJW66543.1 - 0.023 13.8 0.9 0.49 9.4 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 RJW66543.1 - 0.033 14.2 0.1 0.35 10.8 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 RJW66543.1 - 0.043 13.2 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 RJW66543.1 - 0.048 13.7 0.2 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 RJW66543.1 - 0.048 13.9 1.1 0.21 11.9 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain FMO-like PF00743.19 RJW66543.1 - 0.051 12.0 0.1 1.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like F420_oxidored PF03807.17 RJW66543.1 - 0.072 13.7 1.9 0.91 10.2 0.1 3.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent K_oxygenase PF13434.6 RJW66543.1 - 0.096 11.8 0.0 5.4 6.1 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 RJW66543.1 - 0.12 11.2 0.3 0.33 9.7 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase YjeF_N PF03853.15 RJW66543.1 - 0.15 11.9 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 YjeF-related protein N-terminus Shikimate_DH PF01488.20 RJW66543.1 - 0.61 10.1 1.6 28 4.8 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Sulfotransfer_4 PF17784.1 RJW66544.1 - 5.6e-56 189.7 0.1 6.7e-56 189.5 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW66544.1 - 5.1e-07 30.3 0.3 0.00014 22.3 0.2 2.5 2 1 0 2 2 2 1 Sulfotransferase family Antimicrobial_6 PF08036.11 RJW66545.1 - 0.097 12.8 0.3 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide Vac_ImportDeg PF09783.9 RJW66546.1 - 6.3e-45 152.9 0.1 9.9e-45 152.3 0.1 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein zf-H2C2_2 PF13465.6 RJW66547.1 - 3.7e-24 84.0 41.0 2.1e-08 34.2 0.6 6.4 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 RJW66547.1 - 1.3e-19 69.5 43.4 1.2e-05 25.5 0.6 7.1 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66547.1 - 4.4e-12 45.7 34.6 0.0057 17.4 0.6 6.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 RJW66547.1 - 7e-06 26.3 28.0 0.078 13.4 1.6 6.1 6 0 0 6 6 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RJW66547.1 - 1.4e-05 24.9 34.3 0.0024 17.8 1.7 5.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW66547.1 - 0.00035 20.8 25.6 0.04 14.2 0.3 6.0 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RJW66547.1 - 0.043 14.1 20.3 0.81 10.1 11.9 4.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 RJW66547.1 - 0.07 13.4 0.6 13 6.2 0.0 3.2 1 1 3 4 4 4 0 BolA-like protein zf-BED PF02892.15 RJW66547.1 - 1 9.5 15.2 1.2e+03 -0.3 14.4 3.7 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_11 PF16622.5 RJW66547.1 - 1 9.2 18.5 0.097 12.5 1.8 5.1 5 0 0 5 5 5 0 zinc-finger C2H2-type C1_4 PF07975.12 RJW66547.1 - 1.3 9.3 19.3 0.66 10.2 2.9 4.3 3 1 0 4 4 4 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 RJW66547.1 - 3.8 7.7 15.5 7.9 6.7 0.5 4.4 3 1 2 5 5 4 0 Zinc ribbon domain GAGA PF09237.11 RJW66547.1 - 9.1 6.2 8.5 11 6.0 0.5 3.8 1 1 2 4 4 4 0 GAGA factor LRRFIP PF09738.9 RJW66549.1 - 6.4e-40 137.5 26.9 6e-39 134.3 26.9 2.3 1 1 0 1 1 1 1 LRRFIP family DUF1664 PF07889.12 RJW66549.1 - 0.0038 17.2 6.1 0.13 12.3 0.2 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 RJW66549.1 - 0.025 14.7 5.4 0.025 14.7 5.4 3.9 2 2 0 2 2 2 0 Centrosomin N-terminal motif 1 TolA_bind_tri PF16331.5 RJW66549.1 - 0.43 10.7 19.6 0.27 11.3 8.3 3.5 2 2 1 3 3 3 0 TolA binding protein trimerisation APG6_N PF17675.1 RJW66549.1 - 0.98 10.0 25.0 0.5 10.9 7.5 2.9 2 1 1 3 3 3 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 RJW66549.1 - 3 7.9 23.0 8.1 6.5 5.7 3.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pup PF05639.11 RJW66549.1 - 5.4 8.0 5.8 1.1 10.2 0.9 2.3 2 0 0 2 2 2 0 Pup-like protein DUF641 PF04859.12 RJW66549.1 - 8.1 6.8 15.4 0.59 10.5 0.3 3.0 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 RJW66549.1 - 8.7 5.5 7.9 5.4 6.2 0.9 2.2 2 0 0 2 2 2 0 TMPIT-like protein zf-C3HC4_2 PF13923.6 RJW66550.1 - 1.5e-09 37.5 7.5 2.3e-09 36.9 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 RJW66550.1 - 4.6e-09 36.8 0.0 1.8e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4 PF00097.25 RJW66550.1 - 2.5e-08 33.7 8.0 3.7e-08 33.1 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW66550.1 - 3.6e-05 23.6 5.8 6.6e-05 22.8 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RJW66550.1 - 6.1e-05 23.3 6.9 9.6e-05 22.6 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RJW66550.1 - 0.00013 21.7 6.0 0.00019 21.2 6.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RJW66550.1 - 0.00035 20.7 10.0 0.00057 20.0 10.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RJW66550.1 - 0.00078 19.7 3.0 0.0014 18.9 3.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RJW66550.1 - 0.0026 17.7 5.6 0.0057 16.7 5.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 RJW66550.1 - 0.0072 16.1 2.4 0.015 15.1 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 RJW66550.1 - 0.21 11.5 4.7 0.38 10.7 4.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 RJW66550.1 - 2.2 8.2 7.1 5.9 6.8 7.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RNase_T PF00929.24 RJW66551.1 - 1.6e-14 54.8 0.0 2.6e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 RJW66551.1 - 0.11 12.2 0.0 1.3 8.7 0.0 2.2 1 1 0 1 1 1 0 3'-5' exonuclease RVT_1 PF00078.27 RJW66552.1 - 4.4e-39 134.3 0.0 9.8e-39 133.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC2_membrane PF01061.24 RJW66552.1 - 2.3e-33 115.4 25.8 3.5e-33 114.8 25.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter DUF2656 PF10847.8 RJW66552.1 - 0.04 14.0 0.0 0.79 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) PRD1_DD PF11087.8 RJW66553.1 - 0.033 13.9 0.2 7.9 6.3 0.0 2.8 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery UTP25 PF06862.12 RJW66556.1 - 8.7e-108 361.1 0.0 4.2e-74 250.0 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 UCH PF00443.29 RJW66557.1 - 1.1e-46 159.4 0.1 1.3e-46 159.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW66557.1 - 1.2e-10 41.5 0.0 6.5e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.14 RJW66557.1 - 0.026 14.4 2.0 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf_UBZ PF18439.1 RJW66557.1 - 0.44 10.2 2.3 15 5.3 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 RJW66557.1 - 1.1 9.3 7.3 2.4 8.2 1.4 2.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Str_synth PF03088.16 RJW66558.1 - 2.3e-16 59.7 0.0 2.3e-15 56.5 0.0 2.3 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 RJW66558.1 - 5.6e-10 39.2 0.0 5.6e-09 36.0 0.0 2.1 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region C6_DPF PF10170.9 RJW66558.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich domain Arylesterase PF01731.20 RJW66558.1 - 0.15 12.3 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 Arylesterase SVIP PF15811.5 RJW66559.1 - 0.0095 16.4 0.3 0.015 15.7 0.3 1.3 1 0 0 1 1 1 1 Small VCP/p97-interacting protein AA_permease_2 PF13520.6 RJW66564.1 - 5e-57 193.6 47.5 5.9e-57 193.4 47.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RJW66564.1 - 8.4e-25 87.3 42.6 1.2e-24 86.8 42.6 1.2 1 0 0 1 1 1 1 Amino acid permease Hat1_N PF10394.9 RJW66566.1 - 7.7e-08 32.7 0.3 1.3e-07 32.0 0.3 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 RJW66566.1 - 0.1 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family INTAP PF16617.5 RJW66567.1 - 0.0072 16.7 0.1 0.01 16.1 0.1 1.2 1 0 0 1 1 1 1 Intersectin and clathrin adaptor AP2 binding region Metallophos PF00149.28 RJW66568.1 - 2.9e-36 125.9 0.0 4.5e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 RJW66568.1 - 0.00043 19.7 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) DUF1647 PF07801.11 RJW66568.1 - 0.028 14.2 0.4 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Cadherin PF00028.17 RJW66569.1 - 4.9e-60 200.0 2.9 1.5e-15 57.4 0.1 9.7 8 3 0 8 8 8 6 Cadherin domain Cadherin_3 PF16184.5 RJW66569.1 - 8.3e-07 29.0 6.5 0.0051 16.8 0.4 5.7 6 0 0 6 6 6 2 Cadherin-like Cadherin_2 PF08266.12 RJW66569.1 - 0.00087 19.1 0.0 0.068 13.0 0.0 3.8 4 0 0 4 4 4 1 Cadherin-like DUF5072 PF16807.5 RJW66569.1 - 0.011 15.8 0.0 0.056 13.5 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) PyrBI_leader PF08052.11 RJW66569.1 - 0.085 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 PyrBI operon leader peptide Cadherin_4 PF17803.1 RJW66569.1 - 4.5 8.0 14.1 4.3 8.0 0.2 5.1 5 0 0 5 5 5 0 Bacterial cadherin-like domain Spt5-NGN PF03439.13 RJW66570.1 - 1e-25 89.4 0.1 2.1e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 RJW66570.1 - 3.4e-17 61.7 7.0 4e-05 23.4 0.0 6.0 6 0 0 6 6 6 4 KOW motif Spt5_N PF11942.8 RJW66570.1 - 1.1e-08 35.9 18.6 1.1e-08 35.9 18.6 2.8 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal COP-gamma_platf PF08752.10 RJW66570.1 - 4.2 7.5 5.9 13 5.8 5.9 1.8 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain UQ_con PF00179.26 RJW66572.1 - 4e-43 146.4 0.0 4.9e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RJW66572.1 - 2.2e-07 30.7 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.31 RJW66572.1 - 0.00025 20.9 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RWD PF05773.22 RJW66572.1 - 0.0027 18.0 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF647 PF04884.14 RJW66576.1 - 6.9e-88 294.3 2.0 8.6e-88 294.0 2.0 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Innexin PF00876.18 RJW66577.1 - 6.8e-105 351.2 11.3 7.7e-105 351.0 11.3 1.0 1 0 0 1 1 1 1 Innexin Folate_rec PF03024.14 RJW66578.1 - 1.4e-41 142.3 23.0 2e-41 141.8 23.0 1.2 1 0 0 1 1 1 1 Folate receptor family WD40 PF00400.32 RJW66579.1 - 0.0076 17.1 3.9 1.3 10.0 0.1 3.3 3 1 0 3 3 3 2 WD domain, G-beta repeat DUF1741 PF08427.10 RJW66581.1 - 3.5e-42 144.6 0.7 8.6e-42 143.4 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Voltage_CLC PF00654.20 RJW66582.1 - 8.3e-97 324.6 27.9 2.1e-96 323.3 26.0 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 RJW66582.1 - 2e-11 44.2 0.4 1.2e-06 28.9 0.1 2.8 2 0 0 2 2 2 2 CBS domain Tubulin PF00091.25 RJW66583.1 - 1.6e-54 185.1 0.0 2.4e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW66583.1 - 1.9e-43 147.6 0.0 3.5e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW66583.1 - 0.00012 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RJW66583.1 - 0.024 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like MIP PF00230.20 RJW66585.1 - 2.2e-42 145.3 18.8 1.9e-41 142.2 18.8 1.9 1 1 0 1 1 1 1 Major intrinsic protein Peptidase_M16_M PF16187.5 RJW66587.1 - 1.2e-69 234.7 0.0 4.5e-69 232.9 0.0 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 RJW66587.1 - 1.3e-10 41.6 0.2 3.3e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Rap_GAP PF02145.15 RJW66588.1 - 7.9e-39 133.1 0.0 1.5e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP HEAT PF02985.22 RJW66588.1 - 0.35 11.3 3.9 3.4 8.2 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat 7tm_1 PF00001.21 RJW66589.1 - 3.3e-12 46.3 0.4 3.3e-12 46.3 0.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW66589.1 - 0.00067 19.1 0.4 0.00092 18.7 0.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Peptidase_M8 PF01457.16 RJW66590.1 - 1.6e-51 175.6 0.1 9.7e-51 173.0 0.1 1.9 1 1 0 1 1 1 1 Leishmanolysin zf-FCS PF06467.14 RJW66590.1 - 0.085 12.8 0.4 0.35 10.8 0.4 2.1 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif VlpA_repeat PF04649.12 RJW66590.1 - 0.1 12.8 0.1 0.51 10.6 0.1 2.2 1 0 0 1 1 1 0 Mycoplasma hyorhinis VlpA repeat TMEM126 PF07114.11 RJW66591.1 - 1.1e-08 34.7 0.2 2.3e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 Transmembrane protein 126 dCMP_cyt_deam_1 PF00383.23 RJW66591.1 - 2e-06 27.6 2.6 1.2e-05 25.2 1.0 2.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RJW66591.1 - 9.2e-06 25.5 0.8 1.4e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 MafB19-like deaminase Inv-AAD PF18785.1 RJW66591.1 - 0.026 14.4 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase APOBEC2 PF18772.1 RJW66591.1 - 0.037 14.1 0.2 3.6 7.6 0.1 2.4 2 0 0 2 2 2 0 APOBEC2 HMA PF00403.26 RJW66591.1 - 0.13 12.7 0.0 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 Heavy-metal-associated domain SNAD4 PF18750.1 RJW66591.1 - 0.19 11.9 3.1 3.2 7.9 0.0 2.7 3 0 0 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF1325 PF07039.11 RJW66592.1 - 5.7e-15 55.6 0.2 6.6e-15 55.4 0.2 1.1 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 RJW66592.1 - 0.038 13.8 0.5 0.057 13.3 0.5 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain PDE8 PF08629.10 RJW66592.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 PDE8 phosphodiesterase SMC_N PF02463.19 RJW66593.1 - 2.6e-61 206.9 18.7 2.6e-60 203.6 18.7 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RJW66593.1 - 6.9e-24 84.4 0.0 3e-23 82.3 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 RJW66593.1 - 2.1e-15 57.3 1.0 6.2e-08 32.8 0.0 3.8 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RJW66593.1 - 1.3e-08 34.5 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 RJW66593.1 - 1.5e-08 34.8 31.0 1.5e-08 34.8 31.0 4.6 2 2 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 RJW66593.1 - 0.028 14.9 0.0 0.028 14.9 0.0 6.8 4 2 0 4 4 4 0 ABC transporter SbcCD_C PF13558.6 RJW66593.1 - 0.032 14.5 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MafB PF06255.13 RJW66593.1 - 0.085 12.3 0.1 0.22 10.9 0.1 1.6 1 0 0 1 1 1 0 Neisseria toxin MafB T3SS_needle_F PF09392.10 RJW66593.1 - 1.6 9.0 4.4 3.2 8.0 0.1 3.8 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF AAA_23 PF13476.6 RJW66593.1 - 6.3 7.2 131.4 2.8e+02 1.9 64.8 7.3 2 2 0 3 3 3 0 AAA domain PDZ PF00595.24 RJW66594.1 - 5.5e-08 33.0 0.1 1e-07 32.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW66594.1 - 0.00095 19.0 0.0 0.0072 16.1 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Ank_4 PF13637.6 RJW66595.1 - 4.1e-09 36.8 0.3 1.2e-05 25.7 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW66595.1 - 5.6e-09 36.1 0.4 4.2e-05 23.7 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW66595.1 - 9.8e-09 35.7 0.3 0.0002 21.9 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW66595.1 - 0.00015 21.9 1.2 1.6 9.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RJW66595.1 - 0.00016 21.9 1.0 0.85 10.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat ABC_tran PF00005.27 RJW66597.1 - 4.9e-23 82.2 0.0 6.8e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RJW66597.1 - 2.8e-05 23.6 0.0 0.0018 17.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RJW66597.1 - 0.00016 21.6 0.0 0.059 13.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RJW66597.1 - 0.00071 20.1 0.2 0.0011 19.5 0.2 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RJW66597.1 - 0.0013 18.7 0.0 0.0077 16.2 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RJW66597.1 - 0.0059 16.3 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Adeno_IVa2 PF02456.15 RJW66597.1 - 0.03 13.1 0.1 0.048 12.5 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_16 PF13191.6 RJW66597.1 - 0.032 14.6 0.0 0.05 14.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RJW66597.1 - 0.058 13.7 0.0 0.14 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RJW66597.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RJW66597.1 - 0.19 11.0 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 RJW66597.1 - 0.22 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Str_synth PF03088.16 RJW66598.1 - 5.8e-15 55.2 0.0 3e-14 52.9 0.0 2.2 3 0 0 3 3 3 1 Strictosidine synthase SGL PF08450.12 RJW66598.1 - 2.5e-10 40.4 0.0 7.9e-10 38.7 0.0 1.9 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 RJW66598.1 - 0.0015 18.4 0.0 0.63 10.2 0.1 3.3 3 0 0 3 3 3 1 NHL repeat Arylesterase PF01731.20 RJW66598.1 - 0.005 17.0 0.0 0.05 13.8 0.0 2.3 2 0 0 2 2 2 1 Arylesterase Pkinase PF00069.25 RJW66599.1 - 4.9e-31 108.1 0.0 6e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66599.1 - 5.3e-20 71.8 0.0 6.3e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW66599.1 - 0.054 12.8 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RJW66599.1 - 0.056 13.4 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3666 PF12408.8 RJW66600.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase CNPase PF05881.12 RJW66601.1 - 1.7e-23 83.4 0.1 5.6e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) AAA_33 PF13671.6 RJW66601.1 - 9.4e-10 38.8 0.0 1.8e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RJW66601.1 - 0.046 14.1 0.0 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 RJW66601.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RJW66601.1 - 0.14 12.0 0.0 24 4.8 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 RJW66601.1 - 0.16 12.6 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RJW66601.1 - 0.18 11.5 0.0 0.51 10.0 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Tetraspanin PF00335.20 RJW66602.1 - 1.4e-30 106.7 6.5 1.8e-30 106.4 6.5 1.1 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 RJW66602.1 - 0.0039 17.3 5.4 0.0039 17.3 5.4 2.1 2 0 0 2 2 2 1 CD20-like family MARVEL PF01284.23 RJW66602.1 - 0.013 15.6 8.7 2.8 7.9 6.6 2.3 2 0 0 2 2 2 0 Membrane-associating domain DUF998 PF06197.13 RJW66602.1 - 0.024 14.3 8.0 0.25 10.9 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF2871 PF11070.8 RJW66602.1 - 0.065 13.5 4.6 0.13 12.5 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) SUR7 PF06687.12 RJW66602.1 - 0.18 11.4 0.1 0.18 11.4 0.1 3.0 2 2 1 3 3 3 0 SUR7/PalI family Ion_trans PF00520.31 RJW66602.1 - 0.28 10.4 0.0 0.28 10.4 0.0 2.7 2 1 1 3 3 3 0 Ion transport protein Phage_holin_3_6 PF07332.11 RJW66602.1 - 1.5 8.9 19.7 0.73 9.9 4.3 3.0 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Wzy_C PF04932.15 RJW66602.1 - 6.3 6.4 10.7 17 5.0 5.2 2.7 2 1 0 2 2 2 0 O-Antigen ligase PHF12_MRG_bd PF16737.5 RJW66604.1 - 8.9e-07 28.5 0.0 2.6e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 PHD finger protein 12 MRG binding domain PHD PF00628.29 RJW66604.1 - 4.2e-06 26.5 7.3 4.2e-06 26.5 7.3 1.8 2 0 0 2 2 2 1 PHD-finger FHA PF00498.26 RJW66604.1 - 0.002 18.4 0.1 0.0055 17.0 0.1 1.7 1 0 0 1 1 1 1 FHA domain RPAP3_C PF13877.6 RJW66605.1 - 3.6e-16 59.5 0.0 1e-14 54.8 0.0 2.6 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 RJW66605.1 - 9.6e-16 56.9 0.2 0.00054 19.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW66605.1 - 1.1e-12 47.0 1.1 0.0022 18.0 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RJW66605.1 - 1.1e-08 34.6 0.0 2e-06 27.3 0.0 3.0 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 RJW66605.1 - 2.9e-08 34.2 0.7 4.9e-06 27.1 0.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RJW66605.1 - 6.4e-08 32.6 0.7 5.6e-05 23.2 0.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW66605.1 - 5.2e-07 29.4 0.1 0.66 10.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW66605.1 - 0.00025 21.2 0.3 0.13 12.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW66605.1 - 0.001 19.3 2.7 0.44 10.9 1.8 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW66605.1 - 0.0011 18.8 1.1 0.072 13.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RJW66605.1 - 0.0031 18.0 0.2 0.045 14.3 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW66605.1 - 0.0044 17.7 1.2 4.5 8.4 0.0 4.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RJW66605.1 - 0.016 15.8 0.0 1.5 9.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PP-binding_2 PF14573.6 RJW66605.1 - 0.045 14.0 0.3 0.2 11.9 0.1 2.1 2 0 0 2 2 2 0 Acyl-carrier Ly49 PF08391.10 RJW66605.1 - 0.065 13.6 0.4 0.065 13.6 0.4 1.6 2 0 0 2 2 1 0 Ly49-like protein, N-terminal region Fis1_TPR_C PF14853.6 RJW66605.1 - 0.11 12.6 0.6 8.3 6.6 0.2 2.9 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Mating_N PF12731.7 RJW66605.1 - 0.12 12.5 0.6 0.77 9.9 0.2 2.4 2 0 0 2 2 2 0 Mating-type protein beta 1 KinB_sensor PF16767.5 RJW66605.1 - 1.5 9.3 4.6 30 5.1 0.0 2.8 3 0 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB PAX PF00292.18 RJW66608.1 - 1.2e-63 212.6 0.2 2.9e-63 211.4 0.1 1.6 2 0 0 2 2 2 1 'Paired box' domain Homeodomain PF00046.29 RJW66608.1 - 2.9e-13 49.5 0.6 2.9e-13 49.5 0.6 2.7 3 0 0 3 3 3 1 Homeodomain HTH_23 PF13384.6 RJW66608.1 - 0.0005 19.8 0.0 0.00097 18.9 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain SUIM_assoc PF16619.5 RJW66608.1 - 0.013 15.5 8.8 0.045 13.8 3.2 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HTH_Tnp_IS1 PF12759.7 RJW66608.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 InsA C-terminal domain LCAT PF02450.15 RJW66609.1 - 7.9e-49 166.8 0.0 1.4e-45 156.2 0.0 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 RJW66609.1 - 5.3e-05 22.8 0.0 9.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 RJW66609.1 - 0.00012 21.8 0.0 0.0011 18.7 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RJW66609.1 - 0.00021 22.0 0.0 0.00046 20.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 RJW66609.1 - 0.00075 19.3 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 RJW66609.1 - 0.023 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 RJW66609.1 - 0.064 13.1 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Hydrolase_4 PF12146.8 RJW66609.1 - 0.071 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Microtub_bd PF16796.5 RJW66609.1 - 0.089 12.7 0.0 0.34 10.9 0.0 1.8 1 1 1 2 2 2 0 Microtubule binding POPLD PF08170.12 RJW66611.1 - 1.7 9.0 4.4 71 3.8 0.1 3.4 3 0 0 3 3 3 0 POPLD (NUC188) domain 5-FTHF_cyc-lig PF01812.20 RJW66612.1 - 3.5e-42 144.4 0.0 4.2e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family IBP39 PF11422.8 RJW66612.1 - 0.033 13.9 0.3 0.05 13.4 0.3 1.3 1 0 0 1 1 1 0 Initiator binding protein 39 kDa DUF4735 PF15882.5 RJW66612.1 - 0.085 12.3 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) Arf PF00025.21 RJW66613.1 - 0.0018 17.8 0.1 0.0078 15.7 0.0 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 RJW66613.1 - 0.0054 16.9 0.0 0.0097 16.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RJW66613.1 - 0.048 13.6 0.0 3.9 7.3 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase Ras PF00071.22 RJW66613.1 - 0.065 12.8 0.0 1.3 8.6 0.0 2.3 2 1 0 2 2 2 0 Ras family HSCB_C PF07743.13 RJW66613.1 - 0.93 10.0 4.1 0.73 10.4 1.7 2.0 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain NYD-SP28_assoc PF14775.6 RJW66613.1 - 0.99 9.6 4.3 1.3 9.2 0.7 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain SPOC PF07744.13 RJW66615.1 - 4.9e-31 107.7 0.0 1e-30 106.7 0.0 1.6 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 RJW66615.1 - 1.1e-06 28.4 0.0 0.12 12.2 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S12 PF17487.2 RJW66616.1 - 0.043 14.6 0.1 0.074 13.8 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S12 Tubulin PF00091.25 RJW66617.1 - 9.4e-52 176.1 0.0 1.4e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW66617.1 - 4.9e-49 165.7 0.0 7.7e-49 165.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW66617.1 - 0.0034 17.1 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Peptidase_M24 PF00557.24 RJW66619.1 - 2.4e-43 148.3 0.1 3.1e-43 147.9 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 GIY-YIG PF01541.24 RJW66621.1 - 0.011 16.0 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 0 GIY-YIG catalytic domain UPF0542 PF15086.6 RJW66621.1 - 0.011 15.6 0.0 0.33 10.9 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 zf-RING_2 PF13639.6 RJW66624.1 - 2.5e-08 34.1 3.1 2.5e-08 34.1 3.1 1.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 RJW66624.1 - 1.7e-05 24.4 3.4 2.9e-05 23.7 3.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RJW66624.1 - 4.7e-05 23.1 3.4 4.7e-05 23.1 3.4 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RJW66624.1 - 0.00047 19.7 2.3 0.00092 18.8 2.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 RJW66624.1 - 0.0014 18.9 5.8 0.0014 18.9 5.8 2.0 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RJW66624.1 - 0.0017 18.2 2.7 0.0029 17.4 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW66624.1 - 0.0035 17.3 3.6 0.0083 16.1 3.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.6 RJW66624.1 - 0.024 14.6 1.2 0.054 13.4 1.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 RJW66624.1 - 0.058 13.7 2.1 0.096 13.0 2.1 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 RJW66624.1 - 0.081 12.8 1.4 0.16 11.9 1.4 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 RJW66624.1 - 0.41 10.8 4.1 0.82 9.9 4.1 1.5 1 0 0 1 1 1 0 RING-variant domain GIY-YIG PF01541.24 RJW66626.1 - 7.7e-05 22.9 0.6 0.00016 21.9 0.6 1.7 1 1 0 1 1 1 1 GIY-YIG catalytic domain Ribosomal_L44 PF00935.19 RJW66626.1 - 0.11 13.0 0.9 0.22 12.0 0.2 1.9 2 0 0 2 2 2 0 Ribosomal protein L44 CD36 PF01130.21 RJW66627.1 - 1e-104 350.7 0.0 1.3e-104 350.4 0.0 1.0 1 0 0 1 1 1 1 CD36 family Shisa PF13908.6 RJW66627.1 - 0.033 14.4 1.4 0.059 13.6 1.4 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.6 RJW66627.1 - 8.6 6.7 8.5 69 3.8 0.0 3.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal GWT1 PF06423.12 RJW66630.1 - 0.015 15.4 0.9 0.039 14.1 0.9 1.8 1 0 0 1 1 1 0 GWT1 Sec63 PF02889.16 RJW66631.1 - 1.8e-121 404.2 0.0 3.8e-67 226.1 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 RJW66631.1 - 1.2e-29 103.4 0.0 1e-21 77.5 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW66631.1 - 1.3e-14 54.4 0.0 2.8e-06 27.6 0.0 3.4 2 2 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 RJW66631.1 - 1.8e-12 47.6 0.0 3.5e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RJW66631.1 - 9.6e-05 22.7 1.3 0.1 12.8 0.0 3.9 4 1 0 4 4 4 2 AAA domain PhoH PF02562.16 RJW66631.1 - 0.093 12.2 0.1 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 RJW66631.1 - 0.098 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain TMEM132D_C PF15706.5 RJW66632.1 - 0.012 15.4 1.6 0.098 12.4 0.0 2.4 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Baculo_11_kDa PF06143.11 RJW66632.1 - 0.052 13.1 2.9 0.48 10.0 1.0 2.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Cornichon PF03311.14 RJW66632.1 - 0.25 11.7 5.3 0.6 10.4 0.1 2.6 2 0 0 2 2 2 0 Cornichon protein Orf78 PF06024.12 RJW66632.1 - 0.8 10.0 5.0 10 6.5 1.1 2.8 3 0 0 3 3 3 0 Orf78 (ac78) HMGL-like PF00682.19 RJW66633.1 - 9e-30 104.1 0.0 1e-29 104.0 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Calici_coat_C PF08435.11 RJW66634.1 - 0.092 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Mesothelin PF06060.12 RJW66635.1 - 0.0073 14.6 0.0 0.0073 14.6 0.0 1.1 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) 60KD_IMP PF02096.20 RJW66636.1 - 0.4 10.6 13.1 0.37 10.7 13.1 1.0 1 0 0 1 1 1 0 60Kd inner membrane protein PalH PF08733.10 RJW66637.1 - 1.2 8.1 7.2 0.58 9.1 4.7 1.5 1 1 0 2 2 2 0 PalH/RIM21 RRM_1 PF00076.22 RJW66639.1 - 3.4e-13 49.2 0.0 6.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2710 PF10921.8 RJW66639.1 - 0.056 13.9 0.2 0.12 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) Nup35_RRM_2 PF14605.6 RJW66639.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 RJW66639.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Slx4 PF09494.10 RJW66639.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Slx4 endonuclease RVP_2 PF08284.11 RJW66640.1 - 1.7e-09 37.5 1.8 3.2e-09 36.7 1.8 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 RJW66640.1 - 1.7e-05 25.3 0.0 3.2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 RJW66640.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 RJW66640.1 - 0.017 15.8 0.0 0.065 13.9 0.0 2.0 1 1 0 1 1 1 0 Aspartyl protease RVP PF00077.20 RJW66640.1 - 0.077 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 RJW66640.1 - 1.7 8.9 9.4 7.1 6.9 2.2 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 RJW66640.1 - 2.3 8.0 11.0 0.32 10.8 1.5 2.3 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger MutL_C PF08676.11 RJW66641.1 - 7.2e-28 97.2 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 RJW66641.1 - 4.3e-14 52.2 0.0 3.2e-13 49.4 0.0 2.5 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MeMO_Hyd_G PF02964.16 RJW66641.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain Integrase_H2C2 PF17921.1 RJW66642.1 - 2.7e-10 40.2 0.1 4.6e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RJW66642.1 - 0.033 14.4 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DUF656 PF04920.12 RJW66643.1 - 0.0076 16.2 0.0 0.016 15.2 0.0 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF656) BLOC1_2 PF10046.9 RJW66643.1 - 0.064 13.6 2.5 1.9 8.9 0.1 3.2 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2408 PF10303.9 RJW66643.1 - 0.078 13.5 0.9 0.31 11.6 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF5446 PF17522.2 RJW66643.1 - 0.7 10.1 7.0 2.2 8.5 1.7 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5446) zf-C2H2 PF00096.26 RJW66644.1 - 6.2e-23 79.9 42.1 5.3e-05 23.4 4.9 6.3 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66644.1 - 9.4e-21 72.7 40.3 0.0012 19.5 3.8 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW66644.1 - 7.3e-17 61.0 36.4 0.00011 22.4 3.7 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-met PF12874.7 RJW66644.1 - 9.2e-17 60.8 19.6 0.0012 19.1 0.1 6.4 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW66644.1 - 1.6e-10 41.0 26.0 0.024 14.9 0.1 6.5 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW66644.1 - 6.2e-08 32.4 34.5 0.00016 21.5 1.6 6.3 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 RJW66644.1 - 6.3e-06 26.9 22.1 0.032 14.9 0.4 4.5 2 2 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 RJW66644.1 - 0.00017 21.8 26.8 0.28 11.5 6.1 4.3 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 RJW66644.1 - 0.00025 20.9 18.5 0.0029 17.5 0.1 5.5 5 0 0 5 5 5 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 RJW66644.1 - 0.00031 20.4 29.5 0.49 10.2 0.9 6.1 6 0 0 6 6 6 3 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 RJW66644.1 - 0.00055 20.6 13.4 0.61 10.9 0.3 3.3 3 0 0 3 3 3 3 zinc-ribbon family zf-LYAR PF08790.11 RJW66644.1 - 0.00063 19.6 1.7 0.00063 19.6 1.7 4.5 6 0 0 6 6 5 1 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 RJW66644.1 - 0.0017 18.7 28.6 0.99 9.8 2.1 6.2 1 1 4 5 5 5 1 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 RJW66644.1 - 0.002 18.3 21.7 0.057 13.7 2.2 3.6 2 1 2 4 4 4 2 TFIIH C1-like domain Vps36-NZF-N PF16988.5 RJW66644.1 - 0.0044 16.4 9.3 0.0052 16.2 0.0 3.3 3 0 0 3 3 3 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Prok-RING_1 PF14446.6 RJW66644.1 - 0.021 14.7 18.6 4.4 7.3 0.2 6.1 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 zf-H2C2_5 PF13909.6 RJW66644.1 - 0.026 14.3 13.8 1.1 9.1 0.0 4.5 4 0 0 4 4 3 0 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 RJW66644.1 - 0.049 13.5 15.7 1.5 8.7 0.2 5.0 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) Zn_ribbon_SprT PF17283.2 RJW66644.1 - 0.051 13.5 0.9 0.051 13.5 0.9 3.7 3 1 1 4 4 4 0 SprT-like zinc ribbon domain CpXC PF14353.6 RJW66644.1 - 0.062 13.3 18.1 0.49 10.4 2.6 4.8 1 1 3 5 5 5 0 CpXC protein zf_UBZ PF18439.1 RJW66644.1 - 0.086 12.5 18.6 9.7 5.9 0.4 5.8 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger BolA PF01722.18 RJW66644.1 - 0.096 13.0 3.1 16 5.8 0.2 3.6 2 2 1 3 3 3 0 BolA-like protein zf_C2H2_ZHX PF18387.1 RJW66644.1 - 0.1 12.2 0.1 0.1 12.2 0.1 4.3 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn-ribbon_8 PF09723.10 RJW66644.1 - 0.72 10.0 19.3 0.85 9.8 0.6 4.2 3 1 1 4 4 4 0 Zinc ribbon domain DUF3268 PF11672.8 RJW66644.1 - 0.79 10.1 9.8 2.1 8.7 0.4 2.8 2 1 1 3 3 3 0 zinc-finger-containing domain zf-RRPl_C4 PF17026.5 RJW66644.1 - 2 8.5 18.2 9.8 6.3 1.6 2.7 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-WRNIP1_ubi PF18279.1 RJW66644.1 - 2 9.2 6.0 12 6.8 0.9 3.9 3 0 0 3 3 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF2256 PF10013.9 RJW66644.1 - 3.2 7.9 18.7 14 5.9 0.1 5.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.16 RJW66644.1 - 7 6.6 25.8 0.66 9.9 0.9 5.2 6 0 0 6 6 6 0 HIT zinc finger DZR PF12773.7 RJW66644.1 - 8.4 6.5 21.6 18 5.5 1.6 4.4 1 1 1 2 2 1 0 Double zinc ribbon PHF5 PF03660.14 RJW66644.1 - 9.3 6.5 15.3 3.3 8.0 0.3 3.6 1 1 2 4 4 4 0 PHF5-like protein Asp PF00026.23 RJW66645.1 - 1.5e-05 24.6 0.0 1.9e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Claudin_2 PF13903.6 RJW66646.1 - 2.8e-05 23.9 7.3 0.0071 16.1 2.6 2.4 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 RJW66646.1 - 0.082 13.1 3.5 0.53 10.5 2.7 2.1 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Asp PF00026.23 RJW66647.1 - 4.8e-26 91.9 0.0 5.4e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW66647.1 - 2.8e-05 23.9 0.0 0.00045 20.0 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal MMgT PF10270.9 RJW66647.1 - 0.0087 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Membrane magnesium transporter Asp PF00026.23 RJW66648.1 - 1.3e-06 28.1 0.0 1.4e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW66648.1 - 0.00085 19.1 0.0 0.00092 19.0 0.0 1.0 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal tRNA-synt_2 PF00152.20 RJW66650.1 - 2.2e-90 302.9 0.0 3e-90 302.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RJW66650.1 - 2.1e-12 46.9 0.0 3.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.7 RJW66650.1 - 0.018 14.6 0.5 0.046 13.3 0.0 1.7 2 0 0 2 2 2 0 tRNA_anti-like ATPase-cat_bd PF12156.8 RJW66651.1 - 0.022 15.5 2.4 0.032 15.0 2.4 1.3 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase RNA_polI_A14 PF08203.11 RJW66651.1 - 0.19 12.5 1.4 0.3 11.8 1.4 1.4 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Mucin PF01456.17 RJW66651.1 - 2.5 8.1 14.3 2.9 7.9 14.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein HCO3_cotransp PF00955.21 RJW66652.1 - 4.1e-224 745.1 10.9 5.7e-224 744.6 10.9 1.2 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 RJW66652.1 - 1.1e-81 274.6 0.0 1.8e-81 273.9 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Asp PF00026.23 RJW66653.1 - 1e-38 133.5 0.0 1.2e-38 133.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW66653.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 RJW66653.1 - 0.00023 21.5 0.2 0.46 10.7 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RJW66653.1 - 0.0022 18.6 0.5 0.02 15.5 0.0 2.7 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW66653.1 - 0.017 15.7 0.0 0.29 11.7 0.0 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF3443 PF11925.8 RJW66653.1 - 0.074 11.9 0.1 0.42 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3443) Asp PF00026.23 RJW66654.1 - 5.5e-21 75.3 0.2 6.3e-21 75.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 RJW66654.1 - 1.7e-06 28.6 0.1 0.024 15.3 0.1 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.6 RJW66654.1 - 2e-06 28.1 0.3 0.41 10.9 0.0 3.1 2 1 1 3 3 3 3 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 RJW66654.1 - 4.9e-06 27.0 0.0 0.089 13.4 0.0 2.7 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.20 RJW66654.1 - 0.027 14.8 0.0 11 6.4 0.0 2.4 2 1 0 2 2 2 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 RJW66657.1 - 2.3e-08 34.0 0.0 8e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 RJW66657.1 - 0.00076 19.5 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW66658.1 - 5.7e-11 42.3 0.0 8.8e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aminotran_1_2 PF00155.21 RJW66659.1 - 1.5e-69 234.9 0.0 1.7e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CAF1 PF04857.20 RJW66660.1 - 4.8e-24 85.1 1.7 3.7e-12 46.0 0.0 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease DUF2152 PF10222.9 RJW66661.1 - 2e-57 194.9 0.2 3.7e-29 101.6 0.0 2.0 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) BTB PF00651.31 RJW66662.1 - 4.3e-24 84.9 0.0 1.2e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RJW66662.1 - 2.5e-23 82.1 0.1 6.4e-23 80.8 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 RJW66662.1 - 8.3e-18 63.7 3.9 2.2e-10 39.9 1.1 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 RJW66662.1 - 2.7e-10 40.2 0.5 5.3e-05 23.3 0.1 3.5 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.6 RJW66662.1 - 6.7e-06 26.0 0.6 0.25 11.4 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 RJW66662.1 - 7.1e-06 25.8 0.6 0.0037 17.2 0.3 2.9 3 0 0 3 3 3 2 Kelch motif DUF3342 PF11822.8 RJW66662.1 - 0.1 12.8 0.0 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) zf-H2C2_2 PF13465.6 RJW66663.1 - 1.1e-07 32.0 5.2 9e-06 25.9 0.5 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 RJW66663.1 - 2.5e-05 24.4 13.0 0.039 14.4 6.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66663.1 - 0.0073 17.1 9.0 2.6 9.1 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW66663.1 - 0.034 14.4 0.3 0.034 14.4 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4107 PF13389.6 RJW66663.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) zf-DBF PF07535.12 RJW66663.1 - 0.16 12.1 0.4 0.37 11.0 0.4 1.6 1 0 0 1 1 1 0 DBF zinc finger zf-BED PF02892.15 RJW66663.1 - 0.16 12.0 0.6 0.65 10.1 0.6 2.0 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.6 RJW66663.1 - 1.6 8.9 4.6 1.3 9.1 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 RJW66663.1 - 7.8 6.7 8.8 95 3.2 8.8 2.5 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2 PF00096.26 RJW66664.1 - 0.00034 20.9 2.0 0.00067 20.0 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66664.1 - 0.044 14.6 2.2 0.12 13.3 2.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger MRP-L51 PF10244.9 RJW66666.1 - 2.7e-28 98.0 0.3 5e-28 97.2 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit RNA_pol_Rpb5_C PF01191.19 RJW66669.1 - 6.6e-36 122.0 0.4 1.6e-35 120.8 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 RJW66669.1 - 1e-28 99.7 0.2 2e-28 98.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Ribophorin_I PF04597.14 RJW66669.1 - 0.077 12.2 0.3 0.098 11.8 0.3 1.1 1 0 0 1 1 1 0 Ribophorin I RVT_1 PF00078.27 RJW66670.1 - 2.8e-41 141.4 0.0 1.2e-40 139.4 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RICTOR_N PF14664.6 RJW66671.1 - 2.1e-23 82.9 2.5 1.5e-14 53.8 0.0 3.4 2 1 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 RJW66671.1 - 1.6e-09 37.4 0.0 4.4e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 RJW66671.1 - 2.4e-07 30.9 0.4 7.9e-07 29.2 0.4 1.9 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 RJW66671.1 - 0.011 16.1 0.0 0.26 11.7 0.0 3.0 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cir_N PF10197.9 RJW66673.1 - 3.5e-09 36.7 6.2 3.5e-09 36.7 6.2 5.2 6 0 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF148 PF02520.17 RJW66673.1 - 1.5 9.0 6.6 0.12 12.5 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 QVR PF17064.5 RJW66674.1 - 0.0024 18.1 9.8 0.003 17.8 9.8 1.1 1 0 0 1 1 1 1 Sleepless protein Ogr_Delta PF04606.12 RJW66674.1 - 0.79 9.8 6.9 3.3 7.8 0.6 2.5 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Ebp2 PF05890.12 RJW66676.1 - 5e-67 226.3 15.6 5.5e-67 226.1 15.6 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 PG_binding_3 PF09374.10 RJW66676.1 - 0.097 13.0 0.6 0.097 13.0 0.6 2.1 3 0 0 3 3 3 0 Predicted Peptidoglycan domain DDE_3 PF13358.6 RJW66677.1 - 0.047 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease RVT_1 PF00078.27 RJW66678.1 - 7.2e-41 140.1 0.0 1.2e-40 139.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW66678.1 - 7.9e-07 28.9 0.0 2e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase LIG3_BRCT PF16759.5 RJW66680.1 - 0.063 13.6 0.5 21 5.5 0.0 2.6 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain LCE6A PF15858.5 RJW66680.1 - 0.19 12.5 0.8 20 6.0 0.0 2.3 2 0 0 2 2 2 0 Late cornified envelope protein 6A family Sulfotransfer_1 PF00685.27 RJW66683.1 - 8.5e-46 156.6 0.1 1.1e-45 156.2 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW66683.1 - 9.6e-06 26.1 0.0 6e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.10 RJW66683.1 - 0.2 11.1 0.5 6.7 6.2 0.0 2.5 1 1 1 2 2 2 0 Stf0 sulphotransferase Biopterin_H PF00351.21 RJW66684.1 - 9.1e-102 340.5 0.0 1.2e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Pkinase PF00069.25 RJW66686.1 - 3.1e-33 115.3 0.0 4.4e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66686.1 - 5.3e-30 104.6 0.0 6.7e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW66686.1 - 0.00013 22.0 0.0 0.00044 20.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Herpes_UL43 PF05072.13 RJW66686.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL43 protein Golgin_A5 PF09787.9 RJW66688.1 - 4.8e-33 114.9 49.3 3.3e-19 69.5 19.1 3.4 2 1 1 3 3 3 2 Golgin subfamily A member 5 MscS_porin PF12795.7 RJW66688.1 - 0.0035 16.9 23.0 0.0035 16.9 23.0 3.5 2 1 1 3 3 3 1 Mechanosensitive ion channel porin domain ATG16 PF08614.11 RJW66688.1 - 0.0058 16.9 7.6 0.0058 16.9 7.6 4.9 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) zf-CCCH PF00642.24 RJW66692.1 - 4.9e-11 42.3 21.9 8.8e-06 25.5 5.4 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 RJW66692.1 - 2.1e-06 27.4 0.1 3.8e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 RJW66692.1 - 5.6e-05 23.1 13.0 0.034 14.2 2.3 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 RJW66692.1 - 0.0011 19.7 10.0 0.076 13.7 0.3 2.6 2 1 0 2 2 2 2 Torus domain Nup35_RRM_2 PF14605.6 RJW66692.1 - 0.023 14.7 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 RJW66692.1 - 0.063 13.5 7.1 0.42 10.8 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH PF00642.24 RJW66693.1 - 0.0013 18.5 0.8 0.0023 17.8 0.1 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CBFB_NFYA PF02045.15 RJW66693.1 - 0.026 15.1 4.0 0.053 14.1 4.0 1.4 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B LLC1 PF14945.6 RJW66696.1 - 2.3e-26 92.7 0.5 2.7e-26 92.5 0.5 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Cadherin PF00028.17 RJW66698.1 - 1.7e-57 191.8 5.1 6.2e-10 39.4 0.0 10.8 10 1 0 10 10 10 8 Cadherin domain Cadherin_2 PF08266.12 RJW66698.1 - 4.1e-05 23.3 0.1 0.0025 17.6 0.0 3.1 3 0 0 3 3 3 1 Cadherin-like AAA_25 PF13481.6 RJW66698.1 - 0.084 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain BPL_LplA_LipB PF03099.19 RJW66700.1 - 3.9e-06 26.8 0.0 7.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Pkinase PF00069.25 RJW66702.1 - 4.8e-60 203.1 0.0 5.8e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66702.1 - 2.1e-28 99.3 0.0 2.9e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW66702.1 - 3.6e-08 33.1 0.0 5.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW66702.1 - 0.00017 20.7 0.1 0.00022 20.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RTP1_C1 PF10363.9 RJW66703.1 - 7.7e-31 106.6 0.1 2.7e-30 104.8 0.0 2.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 RJW66703.1 - 3.8e-08 33.6 0.4 8.8e-05 22.8 0.0 3.7 2 1 0 2 2 2 2 HEAT repeats Cnd1 PF12717.7 RJW66703.1 - 2.1e-06 27.9 0.1 0.019 15.0 0.0 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RJW66703.1 - 6.6e-06 25.9 0.2 2.4 8.6 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat Vac14_Fab1_bd PF12755.7 RJW66703.1 - 0.019 15.5 0.0 1.4 9.6 0.0 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region C166 PF17615.2 RJW66703.1 - 0.17 12.0 1.5 0.45 10.7 1.5 1.7 1 0 0 1 1 1 0 Family of unknown function HEAT_EZ PF13513.6 RJW66703.1 - 0.18 12.4 1.2 34 5.1 0.1 4.5 3 1 1 4 4 4 0 HEAT-like repeat UPA PF17217.3 RJW66704.1 - 5e-32 110.7 0.0 1.1e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 RJW66704.1 - 1.1e-20 73.8 0.0 2.3e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain Ig_3 PF13927.6 RJW66704.1 - 1.2e-13 51.4 0.0 1e-12 48.5 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RJW66704.1 - 1.7e-12 47.3 0.0 4.2e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW66704.1 - 2.2e-09 37.5 0.0 1.3e-08 35.1 0.0 2.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RJW66704.1 - 2.6e-08 33.9 0.0 2e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 RJW66704.1 - 0.0018 18.3 0.0 0.0086 16.1 0.0 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RJW66704.1 - 0.0024 18.0 0.1 1.5 9.0 0.1 2.8 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 RJW66704.1 - 0.051 14.0 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ras PF00071.22 RJW66705.1 - 1.8e-49 167.4 0.1 2.1e-49 167.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW66705.1 - 1.2e-28 99.7 0.1 1.9e-28 99.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW66705.1 - 1.1e-13 51.1 0.2 1.2e-13 50.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW66705.1 - 3.1e-05 24.0 0.1 4.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RJW66705.1 - 0.00015 21.2 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RJW66705.1 - 0.0022 17.6 0.0 0.0047 16.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 RJW66705.1 - 0.017 14.6 0.0 0.032 13.6 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 RJW66705.1 - 0.049 13.5 0.1 5 7.0 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 RJW66705.1 - 0.085 12.0 0.1 0.28 10.3 0.0 1.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 RJW66705.1 - 0.12 12.8 0.1 0.29 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 RJW66705.1 - 0.14 11.7 0.0 0.73 9.4 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF4611 PF15387.6 RJW66706.1 - 0.049 13.8 3.9 0.082 13.1 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 RJW66706.1 - 0.15 12.5 14.7 0.23 11.9 14.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 RJW66706.1 - 0.16 11.7 1.2 0.25 11.0 1.2 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 RJW66706.1 - 0.65 8.2 4.5 0.76 8.0 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 RJW66706.1 - 0.7 10.3 11.6 1.2 9.5 11.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.9 RJW66706.1 - 0.81 8.8 14.8 0.98 8.5 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Utp14 PF04615.13 RJW66706.1 - 0.82 8.2 5.2 0.91 8.0 5.2 1.0 1 0 0 1 1 1 0 Utp14 protein DNA_pol_phi PF04931.13 RJW66706.1 - 1 7.4 8.9 1.1 7.2 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 RJW66706.1 - 1.8 6.6 2.8 2 6.4 2.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 RJW66706.1 - 2.3 8.2 5.9 3 7.8 5.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 RJW66706.1 - 3.9 5.6 5.4 4.4 5.4 5.4 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 RJW66706.1 - 6.4 5.2 5.2 7.7 4.9 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 RJW66706.1 - 8.3 5.9 6.8 11 5.5 6.8 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NAD_kinase PF01513.21 RJW66707.1 - 3.1e-07 29.9 0.0 7.2e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 RJW66707.1 - 0.086 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain 7tm_1 PF00001.21 RJW66708.1 - 1.1e-09 38.0 7.1 1.1e-09 38.0 7.1 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Ank_2 PF12796.7 RJW66709.1 - 1.6e-39 134.3 4.3 4.4e-09 36.8 0.0 6.4 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW66709.1 - 6.4e-32 109.5 11.5 1.1e-06 29.0 0.1 9.2 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 RJW66709.1 - 1.3e-30 104.5 15.0 0.00054 20.3 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 RJW66709.1 - 1.5e-25 86.4 14.9 0.028 14.9 0.1 10.2 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 RJW66709.1 - 3.3e-18 65.5 12.6 5.3e-08 33.0 0.2 8.9 8 2 1 9 9 9 4 Ankyrin repeats (many copies) Toxin_13 PF07822.11 RJW66709.1 - 0.98 9.6 3.6 1.7 8.8 1.5 2.5 2 0 0 2 2 2 0 Neurotoxin B-IV-like protein Pkinase PF00069.25 RJW66713.1 - 7.2e-63 212.4 0.1 8.8e-63 212.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66713.1 - 2.4e-17 63.1 0.0 3.4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW66713.1 - 5e-06 26.6 3.6 1.1e-05 25.5 0.1 2.6 2 2 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RJW66713.1 - 7.4e-06 25.5 0.2 1.2e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RJW66713.1 - 0.0064 16.1 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 RJW66713.1 - 0.0082 15.0 0.4 0.012 14.4 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase MgtE_N PF03448.17 RJW66713.1 - 0.039 14.6 0.0 9.5 6.9 0.0 2.8 3 0 0 3 3 3 0 MgtE intracellular N domain DUF2459 PF09601.10 RJW66713.1 - 0.15 11.8 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) ELMO_CED12 PF04727.13 RJW66714.1 - 6.5e-12 45.9 0.0 1.8e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 ELMO/CED-12 family His_kinase PF06580.13 RJW66714.1 - 0.1 12.9 0.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase DUF3361 PF11841.8 RJW66714.1 - 0.18 11.7 0.0 0.97 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) RVT_1 PF00078.27 RJW66715.1 - 0.021 14.3 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 RJW66716.1 - 3.2e-17 62.0 20.8 0.00032 21.0 0.2 5.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66716.1 - 6.8e-12 45.2 18.6 0.026 15.3 0.3 5.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW66716.1 - 5e-11 42.5 5.5 3e-06 27.4 0.2 6.1 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_aberr PF17017.5 RJW66716.1 - 0.0073 16.5 2.0 2.2 8.4 0.0 3.1 2 1 1 3 3 3 1 Aberrant zinc-finger Raffinose_syn PF05691.12 RJW66716.1 - 0.071 10.9 0.0 0.1 10.4 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 zf-C2H2_6 PF13912.6 RJW66716.1 - 0.28 11.2 14.9 3.5 7.7 0.2 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger CHORD PF04968.12 RJW66716.1 - 0.54 11.0 7.3 16 6.3 0.7 3.6 2 1 0 3 3 3 0 CHORD IBR PF01485.21 RJW66716.1 - 1.2 9.4 10.5 1.9 8.8 5.1 2.9 1 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-CGNR PF11706.8 RJW66716.1 - 1.6 8.6 5.1 22 5.0 0.3 3.8 3 1 0 3 3 3 0 CGNR zinc finger FOXP-CC PF16159.5 RJW66716.1 - 3.1 8.5 5.6 11 6.7 0.1 2.9 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 RJW66716.1 - 7 6.5 10.9 13 5.7 0.3 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type AAA_6 PF12774.7 RJW66719.1 - 5.4e-26 91.3 0.0 6.1e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region HeH PF12949.7 RJW66723.1 - 0.11 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 HeH/LEM domain MMACHC PF16690.5 RJW66724.1 - 1.2e-67 227.7 0.0 1.4e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Peptidase_C2 PF00648.21 RJW66725.1 - 2e-105 352.1 0.0 2.9e-105 351.5 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RJW66725.1 - 7.4e-37 126.7 0.0 1.3e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 RJW66725.1 - 0.0027 17.1 0.0 0.57 9.9 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 RJW66725.1 - 0.025 14.4 0.1 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 RJW66725.1 - 0.077 13.5 0.7 1.1 9.8 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain pair NHL PF01436.21 RJW66726.1 - 2.5e-13 49.3 7.3 3.4e-06 26.8 0.0 5.6 6 0 0 6 6 6 3 NHL repeat zf-C3HC4_3 PF13920.6 RJW66726.1 - 1.5e-07 31.1 11.1 1.5e-07 31.1 11.1 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RJW66726.1 - 4.8e-05 23.1 13.3 4.8e-05 23.1 13.3 3.3 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RJW66726.1 - 6.3e-05 22.8 14.5 6.3e-05 22.8 14.5 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 RJW66726.1 - 0.00013 22.0 2.1 0.00013 22.0 2.1 4.3 4 0 0 4 4 3 2 B-box zinc finger zf-RING_5 PF14634.6 RJW66726.1 - 0.00019 21.3 11.8 0.00019 21.3 11.8 3.7 3 0 0 3 3 3 1 zinc-RING finger domain LMP PF04778.12 RJW66726.1 - 0.013 15.4 0.3 0.088 12.7 0.1 2.2 1 1 1 2 2 2 0 LMP repeated region Apolipoprotein PF01442.18 RJW66726.1 - 0.015 15.2 1.2 0.037 13.9 1.2 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 RJW66726.1 - 0.023 14.7 0.3 0.043 13.9 0.3 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RHD3 PF05879.12 RJW66726.1 - 0.026 12.7 0.2 0.039 12.1 0.2 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) PIN_8 PF18476.1 RJW66726.1 - 0.05 13.5 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 PIN like domain Cortex-I_coil PF09304.10 RJW66726.1 - 0.058 13.6 1.6 0.18 12.0 1.6 1.8 1 0 0 1 1 1 0 Cortexillin I, coiled coil Cluap1 PF10234.9 RJW66726.1 - 0.058 12.8 0.2 0.097 12.0 0.2 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 BLOC1_2 PF10046.9 RJW66726.1 - 0.075 13.3 1.1 0.26 11.6 0.8 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NAAA-beta PF15508.6 RJW66726.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase FAM184 PF15665.5 RJW66726.1 - 0.14 11.9 2.4 0.15 11.9 0.6 1.9 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B FYVE PF01363.21 RJW66726.1 - 0.27 11.4 22.6 0.71 10.0 7.1 3.7 3 0 0 3 3 3 0 FYVE zinc finger CENP-F_leu_zip PF10473.9 RJW66726.1 - 0.27 11.2 3.1 0.53 10.3 3.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dymeclin PF09742.9 RJW66728.1 - 2e-87 294.1 9.2 2.3e-87 293.9 9.2 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 RJW66728.1 - 2.6e-05 22.6 13.3 0.00014 20.2 12.3 2.2 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein zf-RING_2 PF13639.6 RJW66729.1 - 2.1e-12 47.2 7.0 9.4e-12 45.1 7.0 2.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RJW66729.1 - 1.2e-07 31.3 10.2 1.3e-07 31.2 8.0 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 RJW66729.1 - 5.2e-07 29.4 4.9 5.2e-07 29.4 4.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW66729.1 - 6.4e-07 29.1 7.4 6.4e-07 29.1 7.4 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW66729.1 - 1.5e-05 25.2 8.1 8.6e-05 22.7 8.1 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RJW66729.1 - 3.2e-05 23.8 5.4 0.00016 21.7 5.5 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RJW66729.1 - 5.4e-05 23.1 3.2 5.4e-05 23.1 3.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RJW66729.1 - 0.0013 18.8 4.5 0.0027 17.7 4.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RJW66729.1 - 0.0019 18.0 8.0 0.004 17.0 6.1 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Death_2 PF14786.6 RJW66729.1 - 0.019 14.9 0.0 0.58 10.1 0.0 2.4 2 0 0 2 2 2 0 Tube Death domain Zn_ribbon_17 PF17120.5 RJW66729.1 - 0.043 13.4 6.4 0.1 12.3 6.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 RJW66729.1 - 0.047 13.6 10.4 0.14 12.0 6.6 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 RINGv PF12906.7 RJW66729.1 - 7.8 6.7 10.1 0.52 10.5 4.7 2.0 2 0 0 2 2 1 0 RING-variant domain zf-C4 PF00105.18 RJW66730.1 - 1e-15 57.9 7.0 7.4e-09 35.9 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.5 RJW66730.1 - 0.79 9.9 4.1 1.1 9.4 2.6 2.1 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type ANAPC15 PF15243.6 RJW66730.1 - 0.79 10.2 5.1 1.6 9.2 2.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Gln-synt_C PF00120.24 RJW66734.1 - 9.3e-15 54.5 0.0 1.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 RJW66734.1 - 5.1e-10 38.9 0.0 8.4e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MBOAT PF03062.19 RJW66735.1 - 1.3e-06 28.0 5.8 1.3e-06 28.0 5.8 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CARD_2 PF16739.5 RJW66736.1 - 0.081 12.9 0.1 0.13 12.2 0.1 1.3 1 1 0 1 1 1 0 Caspase recruitment domain UPF0556 PF10572.9 RJW66737.1 - 0.043 13.3 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 CAMSAP_CKK PF08683.11 RJW66738.1 - 5.6e-48 162.0 0.0 9.8e-48 161.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated HSCB_C PF07743.13 RJW66740.1 - 4.8e-15 55.8 4.7 4.8e-15 55.8 4.7 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 RJW66740.1 - 0.0015 18.6 0.1 0.0036 17.4 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain CNOT1_HEAT_N PF16419.5 RJW66740.1 - 0.086 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat LssY_C PF14067.6 RJW66740.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 LssY C-terminus HscB_4_cys PF18256.1 RJW66740.1 - 2.1 8.2 6.1 5.8 6.8 6.1 1.7 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif MFS_1 PF07690.16 RJW66741.1 - 7e-17 61.4 45.0 2.4e-13 49.8 23.1 3.5 3 1 0 3 3 3 2 Major Facilitator Superfamily zf-RING_2 PF13639.6 RJW66742.1 - 4.3e-09 36.6 4.5 4.3e-09 36.6 4.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 RJW66742.1 - 8.7e-07 28.6 2.3 2.2e-06 27.3 2.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 RJW66742.1 - 2.1e-05 24.4 2.1 4e-05 23.5 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RJW66742.1 - 3.1e-05 23.7 5.2 7.2e-05 22.6 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW66742.1 - 5.4e-05 23.0 3.7 0.00011 22.0 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW66742.1 - 5.9e-05 23.3 5.4 0.00018 21.7 5.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 RJW66742.1 - 0.00015 21.3 2.2 0.0003 20.3 2.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RJW66742.1 - 0.00048 20.1 1.8 0.00099 19.1 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RJW66742.1 - 0.00048 19.9 2.1 0.0011 18.8 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW66742.1 - 0.0017 18.4 4.9 0.0036 17.3 4.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger PHD PF00628.29 RJW66742.1 - 0.14 12.1 2.9 0.29 11.1 2.9 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 RJW66742.1 - 1.1 9.3 4.6 2.7 8.0 4.6 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 RJW66742.1 - 1.1 9.1 5.5 10 6.1 5.5 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 RJW66742.1 - 1.2 9.3 4.5 0.76 9.9 1.3 2.3 2 1 0 2 2 2 0 RING-variant domain Vps39_2 PF10367.9 RJW66742.1 - 2.2 8.8 5.5 0.29 11.6 0.2 2.1 3 0 0 3 3 2 0 Vacuolar sorting protein 39 domain 2 Peptidase_M1 PF01433.20 RJW66745.1 - 7.8e-84 280.6 0.0 9.8e-84 280.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RJW66745.1 - 3.8e-37 128.3 0.0 5.8e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Rab5-bind PF09311.11 RJW66746.1 - 0.0032 16.9 14.5 0.0032 16.9 14.5 2.5 3 0 0 3 3 3 1 Rabaptin-like protein DUF4407 PF14362.6 RJW66746.1 - 0.004 16.6 8.9 0.004 16.6 8.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) RB_A PF01858.17 RJW66746.1 - 0.041 13.7 1.0 0.1 12.4 1.0 1.7 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain NAAA-beta PF15508.6 RJW66746.1 - 0.097 13.0 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Gsf2 PF11055.8 RJW66746.1 - 0.12 11.2 2.6 0.17 10.7 0.0 2.4 4 0 0 4 4 4 0 Glucose signalling factor 2 TDA11 PF17084.5 RJW66746.1 - 0.26 10.2 10.8 0.043 12.8 0.3 3.2 3 0 0 3 3 3 0 Topoisomerase I damage affected protein 11 CALCOCO1 PF07888.11 RJW66746.1 - 0.34 9.7 23.4 0.11 11.4 0.3 2.5 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like MobL PF18555.1 RJW66746.1 - 0.44 9.7 13.6 0.019 14.3 7.6 1.6 2 0 0 2 2 2 0 MobL relaxases Lectin_N PF03954.14 RJW66746.1 - 0.45 10.3 5.8 0.61 9.8 0.2 3.3 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Golgin_A5 PF09787.9 RJW66746.1 - 0.49 9.8 28.2 0.11 11.9 7.8 3.5 2 2 1 3 3 3 0 Golgin subfamily A member 5 Rootletin PF15035.6 RJW66746.1 - 1.2 9.1 26.1 7.1 6.6 0.1 3.5 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Scaffolding_pro PF11418.8 RJW66746.1 - 2.7 8.6 6.9 8.4 7.0 0.2 3.3 1 1 2 3 3 3 0 Phi29 scaffolding protein LXG PF04740.12 RJW66746.1 - 4.8 6.8 11.0 0.42 10.3 3.6 3.0 2 1 0 2 2 2 0 LXG domain of WXG superfamily DUF4709 PF15821.5 RJW66746.1 - 5.3 7.4 12.2 1.6 9.0 2.2 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4709) DUF724 PF05266.14 RJW66746.1 - 8.4 6.2 16.2 13 5.5 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Gln-synt_C PF00120.24 RJW66747.1 - 8.2e-17 61.2 0.0 2.7e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 RJW66747.1 - 1.9e-11 43.5 0.0 4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain ThiF PF00899.21 RJW66749.1 - 4.4e-113 376.6 0.0 1.1e-76 257.4 0.0 2.3 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 RJW66749.1 - 2e-88 296.6 0.0 3.1e-88 296.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 RJW66749.1 - 3.7e-34 117.3 0.0 8.5e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 RJW66749.1 - 1.4e-33 114.9 0.3 5.7e-33 112.9 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 RJW66749.1 - 7e-22 77.4 1.4 1.5e-21 76.3 0.7 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle SET PF00856.28 RJW66750.1 - 0.039 14.3 0.0 0.17 12.3 0.0 2.0 1 1 0 1 1 1 0 SET domain PGC7_Stella PF15549.6 RJW66752.1 - 0.62 10.0 2.8 0.93 9.5 0.1 2.4 3 0 0 3 3 3 0 PGC7/Stella/Dppa3 domain 7tm_1 PF00001.21 RJW66753.1 - 1.9e-32 112.6 9.3 3.5e-32 111.8 9.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW66753.1 - 1.9e-07 31.0 18.5 2e-06 27.6 18.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RJW66753.1 - 3.7e-06 26.5 10.4 3.7e-06 26.5 10.4 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Tmemb_9 PF05434.11 RJW66753.1 - 1.5e-05 24.9 2.8 0.024 14.5 0.0 3.0 2 1 1 3 3 3 2 TMEM9 Conotoxin PF02950.17 RJW66753.1 - 0.049 14.6 2.1 0.89 10.6 0.1 2.5 2 0 0 2 2 2 0 Conotoxin DUF4834 PF16118.5 RJW66753.1 - 0.067 14.2 5.1 0.22 12.5 0.1 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) 7tm_4 PF13853.6 RJW66753.1 - 0.069 12.9 15.5 0.16 11.7 15.3 1.4 1 1 0 1 1 1 0 Olfactory receptor DUF1980 PF09323.10 RJW66753.1 - 0.55 10.1 7.6 0.51 10.2 1.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) GIY-YIG PF01541.24 RJW66754.1 - 0.05 13.9 0.2 0.093 13.0 0.2 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain RGS_DHEX PF18148.1 RJW66757.1 - 2.4e-39 133.4 0.1 4.9e-39 132.5 0.1 1.5 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 RJW66757.1 - 9.9e-30 103.2 0.2 2.2e-29 102.1 0.2 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 RJW66757.1 - 1.4e-18 66.7 0.0 5e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 RJW66757.1 - 0.00098 19.1 2.6 0.0022 17.9 0.0 2.6 3 0 0 3 3 3 1 GGL domain Slx4 PF09494.10 RJW66757.1 - 0.019 14.9 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Slx4 endonuclease RGS-like PF09128.11 RJW66757.1 - 0.028 14.1 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain RVT_1 PF00078.27 RJW66758.1 - 6e-14 52.1 0.0 7e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 RJW66761.1 - 1.3e-18 66.4 17.6 8.8e-09 35.0 0.2 5.6 3 2 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RJW66761.1 - 8.4e-14 51.5 28.2 0.002 18.5 0.7 6.8 3 1 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW66761.1 - 2e-06 27.4 1.3 2e-06 27.4 1.3 2.4 1 1 0 2 2 2 1 Leucine-rich repeat LRR_5 PF13306.6 RJW66761.1 - 2.4e-06 27.6 2.1 6.5e-05 22.9 0.3 2.7 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RJW66761.1 - 0.00048 20.3 24.7 1.5 9.7 0.3 7.4 7 1 0 7 7 7 2 Leucine Rich Repeat Baculo_PEP_C PF04513.12 RJW66761.1 - 0.041 13.9 0.3 0.041 13.9 0.3 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_6 PF13516.6 RJW66761.1 - 0.073 13.2 26.0 1.6 9.0 2.1 7.6 8 0 0 8 8 8 0 Leucine Rich repeat Calreticulin PF00262.18 RJW66762.1 - 1.1e-82 277.9 16.4 3.9e-61 207.0 8.7 2.3 1 1 1 2 2 2 2 Calreticulin family SHR3_chaperone PF08229.11 RJW66762.1 - 3.4 6.6 4.3 4.3 6.3 0.0 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 Adeno_PV PF03910.13 RJW66762.1 - 5.4 5.6 6.5 8.8 4.9 6.5 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV zf-RING_6 PF14835.6 RJW66764.1 - 0.49 10.3 6.7 2.7 7.9 0.4 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF2282 PF10048.9 RJW66764.1 - 4.8 7.3 14.6 1.3 9.1 2.3 2.7 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2282) Kelch_3 PF13415.6 RJW66766.1 - 8.1e-26 89.8 7.2 3e-06 27.4 0.0 7.7 7 1 1 8 8 8 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RJW66766.1 - 3.5e-25 87.8 7.9 1.8e-06 27.9 0.1 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW66766.1 - 7.2e-23 80.1 5.7 4.8e-06 26.4 0.0 6.6 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 RJW66766.1 - 2.4e-18 65.7 6.9 5.9e-05 23.2 0.1 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 RJW66766.1 - 2.1e-09 36.8 3.5 0.0062 16.1 0.0 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 RJW66766.1 - 0.00058 19.7 10.4 0.0037 17.2 0.3 5.0 6 0 0 6 6 6 1 Kelch motif DUF4110 PF13422.6 RJW66766.1 - 0.22 11.6 0.2 0.22 11.6 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) DUF2457 PF10446.9 RJW66766.1 - 5.2 6.1 10.9 10 5.1 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1676 PF07898.13 RJW66767.1 - 0.76 9.8 8.6 0.89 9.6 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) zf-rbx1 PF12678.7 RJW66768.1 - 1.9e-19 69.7 11.2 4.6e-19 68.5 11.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RJW66768.1 - 1.1e-14 54.2 11.7 2.7e-14 53.0 11.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 RJW66768.1 - 0.0052 16.6 2.2 0.0052 16.6 2.2 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW66768.1 - 0.21 11.5 11.7 1.6 8.6 11.6 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW66768.1 - 0.48 10.8 23.0 0.081 13.3 14.6 2.9 2 1 0 2 2 2 0 Ring finger domain Zn_ribbon_17 PF17120.5 RJW66768.1 - 1.5 8.5 15.6 0.65 9.7 9.6 2.6 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type DUF4698 PF15769.5 RJW66771.1 - 0.0087 15.2 2.9 0.012 14.7 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) Mucin PF01456.17 RJW66771.1 - 0.085 12.8 18.8 0.17 11.9 18.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 RJW66771.1 - 6.3 4.6 6.9 7.6 4.4 6.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 RJW66771.1 - 6.9 4.7 17.1 9.8 4.2 17.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tir_receptor_C PF07489.11 RJW66771.1 - 7.9 6.4 12.4 15 5.4 12.4 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Pkinase PF00069.25 RJW66772.1 - 2.6e-58 197.5 0.0 3.7e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66772.1 - 9.5e-24 84.1 0.0 1.5e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW66772.1 - 0.0043 16.4 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 Kinase-like PliI PF16743.5 RJW66772.1 - 0.041 13.6 0.1 6.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Periplasmic lysozyme inhibitor of I-type lysozyme Kdo PF06293.14 RJW66772.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW66772.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ig_3 PF13927.6 RJW66773.1 - 1.2e-23 83.5 0.9 1.2e-14 54.7 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RJW66773.1 - 2.2e-20 72.5 0.0 1.4e-11 44.3 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 RJW66773.1 - 1.1e-16 60.8 0.1 9.9e-08 32.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RJW66773.1 - 1.3e-14 54.2 0.6 2.3e-06 27.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RJW66773.1 - 3.8e-05 23.8 0.2 2.8 8.1 0.0 3.7 3 1 1 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 RJW66773.1 - 0.0024 17.4 0.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 RJW66773.1 - 0.012 15.6 0.0 0.89 9.7 0.0 2.5 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 RJW66773.1 - 0.025 15.0 0.0 0.58 10.6 0.0 2.5 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain PEHE PF15275.6 RJW66774.1 - 5.5e-23 82.0 1.1 5.5e-23 82.0 1.1 4.2 5 1 0 5 5 5 1 PEHE domain RVT_1 PF00078.27 RJW66776.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Rubredoxin_2 PF18073.1 RJW66778.1 - 0.089 12.5 1.3 0.27 11.0 1.3 1.9 1 0 0 1 1 1 0 Rubredoxin metal binding domain Ldl_recept_a PF00057.18 RJW66778.1 - 0.27 11.5 3.1 0.99 9.7 3.1 2.0 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A zf-CW PF07496.15 RJW66779.1 - 0.013 15.5 0.1 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 CW-type Zinc Finger zf-C4 PF00105.18 RJW66780.1 - 4.8e-27 94.2 14.9 8.5e-27 93.4 14.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW66780.1 - 1e-15 57.9 0.0 1.8e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DDE_Tnp_IS1595 PF12762.7 RJW66781.1 - 0.011 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 ISXO2-like transposase domain DUF667 PF05018.13 RJW66782.1 - 1.6e-72 243.1 0.1 1.8e-72 243.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Hexokinase_2 PF03727.16 RJW66785.1 - 2e-55 187.8 0.0 2.4e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Hexokinase Pkinase PF00069.25 RJW66787.1 - 8e-12 45.1 0.1 2.4e-11 43.5 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66787.1 - 0.0015 17.9 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HLH PF00010.26 RJW66788.1 - 0.015 15.3 0.1 0.015 15.3 0.1 2.1 2 1 1 3 3 3 0 Helix-loop-helix DNA-binding domain Nipped-B_C PF12830.7 RJW66791.1 - 0.092 12.7 0.0 0.1 12.6 0.0 1.0 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus G-gamma PF00631.22 RJW66794.1 - 0.3 11.1 4.4 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 GGL domain BCDHK_Adom3 PF10436.9 RJW66795.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Tweety PF04906.13 RJW66795.1 - 0.28 9.8 1.5 0.43 9.2 1.5 1.1 1 0 0 1 1 1 0 Tweety Mito_carr PF00153.27 RJW66796.1 - 1.8e-67 223.3 1.9 6.2e-23 80.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MBT PF02820.18 RJW66797.1 - 8.1e-38 128.6 0.3 1.7e-15 57.1 0.0 4.7 4 0 0 4 4 4 4 mbt repeat SLED PF12140.8 RJW66797.1 - 3.4e-16 59.8 0.0 4.4e-15 56.2 0.0 2.4 1 1 0 1 1 1 1 SLED domain cEGF PF12662.7 RJW66799.1 - 2.4e-11 43.4 59.5 0.0025 17.7 2.0 8.7 8 0 0 8 8 8 6 Complement Clr-like EGF-like EGF_CA PF07645.15 RJW66799.1 - 9.7e-09 35.3 23.6 2.9e-08 33.8 9.5 8.5 8 0 0 8 8 8 5 Calcium-binding EGF domain EGF PF00008.27 RJW66799.1 - 1.2e-07 31.8 110.4 0.0039 17.5 8.7 9.8 9 1 1 10 10 10 7 EGF-like domain hEGF PF12661.7 RJW66799.1 - 7.6e-06 26.4 99.0 0.011 16.4 6.2 9.9 9 0 0 9 9 9 6 Human growth factor-like EGF EGF_2 PF07974.13 RJW66799.1 - 0.0022 18.3 12.0 0.0022 18.3 12.0 9.9 8 1 1 9 9 9 5 EGF-like domain Plasmod_Pvs28 PF06247.11 RJW66799.1 - 0.0028 17.9 6.4 0.0028 17.9 6.4 7.6 7 0 0 7 7 7 3 Pvs28 EGF domain Hexokinase_1 PF00349.21 RJW66800.1 - 1.4e-13 51.2 0.1 1.7e-13 50.9 0.1 1.0 1 0 0 1 1 1 1 Hexokinase Torsin PF06309.11 RJW66804.1 - 1.2e-37 128.9 2.4 1.9e-37 128.2 2.4 1.4 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.6 RJW66804.1 - 0.0094 16.3 0.1 4.8 7.5 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain ResIII PF04851.15 RJW66804.1 - 0.01 15.9 0.0 1.8 8.5 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 RJW66804.1 - 0.039 14.4 0.0 0.084 13.3 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RJW66804.1 - 0.085 13.1 0.0 0.68 10.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 RJW66805.1 - 4e-35 121.4 0.0 1.2e-34 120.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66805.1 - 1.5e-14 53.9 0.0 2.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 RJW66805.1 - 4.5e-11 43.3 2.7 6e-10 39.7 1.5 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain DUF269 PF03270.13 RJW66805.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF269 ATG16 PF08614.11 RJW66805.1 - 0.12 12.6 50.8 0.012 15.9 8.8 4.4 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF3496 PF12001.8 RJW66805.1 - 6 7.3 19.4 3.4 8.1 1.6 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3496) GIT1_C PF12205.8 RJW66805.1 - 6.7 6.9 9.7 2.2 8.4 0.6 3.2 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF4263 PF14082.6 RJW66807.1 - 0.1 12.8 0.1 0.14 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) Rota_NSP3 PF01665.16 RJW66807.1 - 0.14 11.3 0.4 0.18 10.9 0.4 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 RNase_Zc3h12a PF11977.8 RJW66810.1 - 7e-37 126.6 0.0 9.3e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain DUF5615 PF18480.1 RJW66810.1 - 0.1 12.4 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) PRORP PF16953.5 RJW66810.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-only RNase P C2 PF00168.30 RJW66811.1 - 0.0002 21.6 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain ABC_tran_CTD PF16326.5 RJW66811.1 - 0.027 14.7 0.0 0.33 11.2 0.0 2.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain GPS2_interact PF15784.5 RJW66811.1 - 0.56 10.7 4.3 7.1 7.1 0.5 3.7 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain RRM_1 PF00076.22 RJW66814.1 - 4.1e-12 45.7 0.0 8.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 RJW66814.1 - 3.5e-06 26.9 1.7 3.5e-06 26.9 1.7 1.9 2 0 0 2 2 2 1 Zinc finger domain RRM_occluded PF16842.5 RJW66814.1 - 3.5e-06 26.8 0.1 9e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 RJW66814.1 - 9.7e-06 25.5 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Torus PF16131.5 RJW66814.1 - 4.2e-05 24.2 0.1 8.7e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 RJW66814.1 - 0.0032 17.2 2.2 0.0069 16.2 2.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 RJW66814.1 - 0.0054 16.6 2.0 0.0054 16.6 2.0 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 RJW66814.1 - 0.015 15.7 0.4 0.015 15.7 0.4 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RRM_3 PF08777.11 RJW66814.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif zf-CCCH_3 PF15663.5 RJW66814.1 - 0.016 15.4 0.2 0.046 13.9 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger containing family RRM_7 PF16367.5 RJW66814.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif FYVE PF01363.21 RJW66814.1 - 0.26 11.5 6.1 0.13 12.5 3.6 1.8 2 0 0 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 RJW66814.1 - 0.51 10.4 7.2 1.1 9.3 7.2 1.6 1 0 0 1 1 1 0 zinc-ribbons EAP30 PF04157.16 RJW66815.1 - 1.6e-63 214.1 0.0 1.9e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family EutK_C PF16365.5 RJW66815.1 - 0.033 14.2 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus RNase_Zc3h12a PF11977.8 RJW66816.1 - 4.7e-30 104.4 0.0 6.4e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 RJW66816.1 - 0.044 13.3 0.0 0.087 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein-only RNase P DUF5615 PF18480.1 RJW66816.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) SabA_adhesion PF18304.1 RJW66817.1 - 0.064 12.5 0.3 0.14 11.4 0.3 1.5 1 1 1 2 2 2 0 SabA N-terminal extracellular adhesion domain Exotox-A_bind PF09101.10 RJW66818.1 - 0.18 11.1 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A binding HIG_1_N PF04588.13 RJW66820.1 - 3.5e-08 33.5 2.2 5.2e-08 33.0 1.7 1.6 1 1 1 2 2 2 1 Hypoxia induced protein conserved region zf-Di19 PF05605.12 RJW66821.1 - 1.5e-11 44.4 3.1 3.8e-11 43.1 3.1 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 RJW66821.1 - 0.39 11.0 2.3 16 5.8 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon RVT_1 PF00078.27 RJW66823.1 - 2.5e-05 23.9 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_B_2 PF03175.13 RJW66823.1 - 0.18 10.6 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Mito_carr PF00153.27 RJW66824.1 - 9.9e-64 211.3 2.8 5.3e-24 84.0 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 RJW66824.1 - 0.083 12.1 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Fuseless Forkhead PF00250.18 RJW66825.1 - 6.9e-38 128.8 0.0 1.2e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Parvo_NS1 PF01057.17 RJW66826.1 - 4.4e-14 52.2 0.0 6.3e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 RJW66826.1 - 1.1e-10 41.0 0.1 1.6e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Papillomavirus helicase T2SSE PF00437.20 RJW66826.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1778 PF08681.11 RJW66826.1 - 0.041 13.8 0.2 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) TsaE PF02367.17 RJW66826.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CAP PF00188.26 RJW66827.1 - 2.1e-14 54.4 0.0 2.6e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Asp PF00026.23 RJW66828.1 - 4.9e-18 65.6 0.5 6.4e-18 65.2 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW66828.1 - 0.049 13.9 0.2 1 9.6 0.2 2.2 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Enolase_N PF03952.16 RJW66829.1 - 1.8e-52 177.0 0.0 2.3e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, N-terminal domain Enolase_C PF00113.22 RJW66829.1 - 2e-37 129.1 0.0 3.3e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain DUF3421 PF11901.8 RJW66830.1 - 5.2e-43 145.7 5.9 8.2e-40 135.4 4.0 2.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) DUF3421 PF11901.8 RJW66832.1 - 1.5e-32 111.9 0.7 4e-31 107.4 0.2 2.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) DUF3421 PF11901.8 RJW66833.1 - 1.7e-39 134.4 3.4 6.5e-37 126.0 1.6 2.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) TED_complement PF07678.14 RJW66834.1 - 1.4e-69 234.5 0.2 2.2e-69 233.9 0.2 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain MG3 PF17791.1 RJW66834.1 - 4.1e-24 84.7 0.0 1.2e-23 83.1 0.0 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG3 A2M_recep PF07677.14 RJW66834.1 - 5.1e-23 81.6 0.0 2.1e-22 79.6 0.0 2.2 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain A2M PF00207.22 RJW66834.1 - 1.3e-15 57.0 0.4 6.1e-15 54.9 0.1 2.4 2 0 0 2 2 1 1 Alpha-2-macroglobulin family MG2 PF01835.19 RJW66834.1 - 5.9e-09 36.3 0.1 9.1e-06 26.0 0.1 3.9 2 1 0 2 2 2 1 MG2 domain DSL PF01414.19 RJW66834.1 - 1.2e-05 25.5 4.4 1.2e-05 25.5 4.4 2.9 2 0 0 2 2 2 1 Delta serrate ligand A2M_BRD PF07703.14 RJW66834.1 - 3.2e-05 24.3 0.7 0.0038 17.6 0.0 3.9 5 0 0 5 5 5 1 Alpha-2-macroglobulin bait region domain HRXXH PF13933.6 RJW66834.1 - 0.0083 15.7 0.6 0.02 14.5 0.6 1.6 1 0 0 1 1 1 1 Putative peptidase family MG4 PF17789.1 RJW66834.1 - 0.055 13.6 0.0 2.4 8.4 0.0 3.4 3 0 0 3 3 3 0 Macroglobulin domain MG4 RNA_pol_inhib PF16857.5 RJW66834.1 - 0.074 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase inhibitor Prenyltrans PF00432.21 RJW66834.1 - 0.31 10.8 1.4 27 4.6 0.0 3.7 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat EGF_2 PF07974.13 RJW66834.1 - 4.4 7.8 43.5 0.21 12.0 11.8 4.3 4 0 0 4 4 4 0 EGF-like domain Ras PF00071.22 RJW66837.1 - 2.1e-47 160.7 0.0 2.5e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW66837.1 - 6.1e-27 94.2 0.0 9e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW66837.1 - 6.1e-15 55.1 0.0 7.7e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW66837.1 - 2.8e-06 26.9 0.0 7.6e-05 22.2 0.0 2.1 1 1 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RJW66837.1 - 6.4e-05 23.0 0.0 9.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RJW66837.1 - 0.015 14.7 0.0 0.063 12.7 0.0 1.8 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 RJW66837.1 - 0.11 12.2 0.0 0.52 10.0 0.0 1.8 1 1 0 2 2 2 0 AAA domain Septin PF00735.18 RJW66837.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin Colicin PF01024.19 RJW66837.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Colicin pore forming domain UCH PF00443.29 RJW66838.1 - 2.3e-30 106.0 0.0 3.6e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RJW66838.1 - 4.3e-16 59.0 0.0 1.4e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 RJW66838.1 - 6.5e-12 45.1 0.9 1.5e-07 31.2 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 RJW66838.1 - 2.8e-06 27.2 0.0 0.094 12.3 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ZipA_C PF04354.13 RJW66844.1 - 0.026 14.4 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain ComGF PF15980.5 RJW66844.1 - 0.082 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative Competence protein ComGF SAP PF02037.27 RJW66845.1 - 4.2e-05 23.2 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 RJW66845.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain Erf4 PF10256.9 RJW66846.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family TRAPPC-Trs85 PF12739.7 RJW66847.1 - 8.7e-97 324.6 1.0 1.8e-96 323.6 1.0 1.6 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Radial_spoke_3 PF06098.11 RJW66849.1 - 5.8e-53 180.0 8.0 5.8e-53 180.0 8.0 1.9 2 0 0 2 2 2 1 Radial spoke protein 3 AceK PF06315.11 RJW66849.1 - 0.0018 16.8 1.9 0.0023 16.5 1.9 1.1 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) HIGH_NTase1_ass PF16581.5 RJW66849.1 - 0.11 12.4 1.5 0.25 11.3 0.3 2.0 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region TPR_3 PF07720.12 RJW66849.1 - 0.43 10.6 2.4 0.36 10.9 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Steroid_dh PF02544.16 RJW66850.1 - 1.2e-24 87.0 1.4 2.1e-24 86.2 1.4 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 RJW66850.1 - 0.0038 17.6 0.3 0.0038 17.6 0.3 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase SIS PF01380.22 RJW66851.1 - 1.3e-59 199.7 0.0 1.4e-31 109.1 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 RJW66851.1 - 4.2e-17 62.6 0.0 8.8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RJW66851.1 - 6.7e-13 48.6 0.0 1.6e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 RJW66851.1 - 8.3e-05 21.6 0.1 0.00014 20.9 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 RJW66851.1 - 0.066 13.2 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 SIS domain DUF3894 PF13033.6 RJW66851.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) RVT_1 PF00078.27 RJW66852.1 - 0.0062 16.1 0.0 0.027 14.0 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACT_5 PF13710.6 RJW66852.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 ACT domain DUF2536 PF10750.9 RJW66853.1 - 0.03 14.2 0.1 9.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) EMP70 PF02990.16 RJW66854.1 - 6.5e-138 460.6 27.6 6.5e-138 460.6 27.6 1.8 2 0 0 2 2 2 1 Endomembrane protein 70 TraP PF07296.11 RJW66854.1 - 1.8 7.7 3.5 1.4 8.1 1.9 1.6 2 0 0 2 2 2 0 TraP protein PMP22_Claudin PF00822.20 RJW66856.1 - 4.5e-10 39.6 10.7 7.1e-10 39.0 10.7 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RJW66856.1 - 0.34 10.7 19.1 4 7.2 19.1 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Asp PF00026.23 RJW66857.1 - 9.3e-11 41.7 0.0 1.1e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Neur_chan_LBD PF02931.23 RJW66859.1 - 1.6e-05 24.4 0.4 0.00016 21.2 0.4 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW66859.1 - 0.00019 21.6 5.9 0.00035 20.7 5.9 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3043 PF11241.8 RJW66859.1 - 0.16 12.0 0.3 0.34 10.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) YqfD PF06898.11 RJW66859.1 - 0.19 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD DUF2070 PF09843.9 RJW66859.1 - 0.93 7.7 5.1 1.2 7.3 5.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) fn3 PF00041.21 RJW66860.1 - 3.6e-11 43.2 1.8 0.12 12.7 0.0 4.4 4 0 0 4 4 4 3 Fibronectin type III domain PDZ_4 PF17816.1 RJW66860.1 - 5.4e-05 23.6 0.0 4.8 7.6 0.0 4.3 4 0 0 4 4 4 2 PDZ domain Glyco_hydro_36N PF16875.5 RJW66860.1 - 0.091 12.3 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 36 N-terminal domain CBFD_NFYB_HMF PF00808.23 RJW66862.1 - 4.4e-13 49.3 0.0 7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 RJW66862.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated EBP50_C PF09007.11 RJW66862.1 - 0.0097 16.9 0.1 0.0097 16.9 0.1 1.8 2 0 0 2 2 2 1 EBP50, C-terminal Histone PF00125.24 RJW66862.1 - 0.043 14.2 0.1 0.043 14.2 0.1 1.8 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAF PF02969.17 RJW66862.1 - 0.067 13.4 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) RVT_1 PF00078.27 RJW66863.1 - 0.081 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 RJW66863.1 - 0.089 12.6 0.0 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP PF00188.26 RJW66864.1 - 8.9e-17 62.1 0.0 1.2e-16 61.7 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_M17 PF00883.21 RJW66865.1 - 1.6e-98 329.8 0.0 2.2e-81 273.6 0.1 2.1 2 0 0 2 2 2 2 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 RJW66865.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Cse1 PF08506.10 RJW66866.1 - 2.5e-120 401.7 0.0 4.2e-120 401.0 0.0 1.4 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 RJW66866.1 - 3.6e-82 276.2 1.4 6.7e-42 143.5 1.1 3.5 3 1 0 3 3 3 3 CAS/CSE protein, C-terminus IBN_N PF03810.19 RJW66866.1 - 4.8e-14 52.0 0.0 1.4e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 RJW66866.1 - 0.02 14.9 0.9 0.22 11.6 0.0 3.2 3 1 0 3 3 3 0 Exportin 1-like protein DUF3437 PF11919.8 RJW66866.1 - 0.021 14.7 0.0 2.4 8.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF3385 PF11865.8 RJW66866.1 - 0.053 13.4 0.4 0.5 10.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) UPF0193 PF05250.11 RJW66869.1 - 2.4e-17 63.5 5.8 3.9e-17 62.8 5.8 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) Integrase_H2C2 PF17921.1 RJW66870.1 - 0.017 15.2 0.7 5.9 7.1 0.0 2.7 3 0 0 3 3 3 0 Integrase zinc binding domain Death_2 PF14786.6 RJW66870.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Tube Death domain DUF2475 PF10629.9 RJW66871.1 - 0.0028 17.8 0.0 0.0068 16.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) RVT_1 PF00078.27 RJW66872.1 - 3.6e-46 157.5 0.0 1.2e-45 155.8 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2OG-FeII_Oxy_4 PF13661.6 RJW66872.1 - 1.2e-16 61.2 0.1 5.4e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 RJW66872.1 - 5.9e-12 46.3 0.0 1.8e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Exo_endo_phos_2 PF14529.6 RJW66872.1 - 4.3e-11 42.7 0.0 2e-10 40.6 0.0 2.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Ofd1_CTDD PF10637.9 RJW66872.1 - 3.4e-08 33.2 0.0 2.3e-07 30.4 0.0 2.3 3 0 0 3 3 3 1 Oxoglutarate and iron-dependent oxygenase degradation C-term RVT_1 PF00078.27 RJW66873.1 - 2.5e-45 154.7 0.0 4.5e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Motile_Sperm PF00635.26 RJW66874.1 - 3.9e-41 139.3 0.2 6.5e-24 83.9 0.0 2.2 2 0 0 2 2 2 2 MSP (Major sperm protein) domain ASH PF15780.5 RJW66874.1 - 0.003 17.7 0.6 0.1 12.8 0.2 2.7 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin HMG_box PF00505.19 RJW66875.1 - 8e-08 32.6 0.0 2.5e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW66875.1 - 8.7e-05 23.0 0.1 0.00019 22.0 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain VATC PF18716.1 RJW66875.1 - 0.055 13.3 2.7 0.092 12.6 1.8 1.9 1 1 0 1 1 1 0 Vms1-associating treble clef domain Peptidase_A17 PF05380.13 RJW66876.1 - 4.8e-06 26.7 0.1 9.6e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 RJW66876.1 - 0.0002 21.4 2.7 0.0002 21.4 2.7 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain Thioredoxin PF00085.20 RJW66879.1 - 2.4e-61 204.1 0.0 1.6e-29 101.9 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 RJW66879.1 - 1.5e-10 41.4 3.3 0.0021 18.5 0.1 5.1 3 3 1 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 RJW66879.1 - 1.1e-06 28.3 0.0 0.042 13.2 0.0 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 RJW66879.1 - 3.4e-06 27.0 0.0 0.08 13.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_8 PF13905.6 RJW66879.1 - 1.2e-05 25.5 0.1 0.05 13.9 0.0 4.1 2 2 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 RJW66879.1 - 5.5e-05 23.3 0.1 0.64 10.2 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 RJW66879.1 - 0.00014 21.8 0.1 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 RJW66879.1 - 0.011 15.5 0.0 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin DIM1 PF02966.16 RJW66879.1 - 0.028 14.2 0.0 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Mitosis protein DIM1 HyaE PF07449.11 RJW66879.1 - 0.029 14.3 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE FancD2 PF14631.6 RJW66879.1 - 0.054 10.9 0.0 2.9 5.2 0.0 2.0 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease TraF PF13728.6 RJW66879.1 - 0.13 12.1 0.0 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein DUF5427 PF10310.9 RJW66882.1 - 0.0062 15.6 0.4 0.0073 15.3 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) UPF0182 PF03699.13 RJW66883.1 - 4.9 5.2 9.7 6.2 4.8 9.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Yippee-Mis18 PF03226.14 RJW66884.1 - 1.1e-10 41.7 0.2 1.7e-10 41.0 0.2 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LA-virus_coat PF09220.10 RJW66884.1 - 0.18 10.4 0.1 0.27 9.8 0.1 1.2 1 0 0 1 1 1 0 L-A virus, major coat protein Zn_ribbon_SprT PF17283.2 RJW66884.1 - 9.1 6.3 7.7 1.3 8.9 0.6 2.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Homeodomain PF00046.29 RJW66885.1 - 5.6e-24 83.8 0.4 1.3e-23 82.6 0.1 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RJW66885.1 - 0.00055 19.8 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain LRR_4 PF12799.7 RJW66886.1 - 5.5e-14 52.1 18.7 0.00042 20.6 0.2 4.9 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW66886.1 - 6.1e-10 38.7 16.5 7e-06 25.7 3.8 4.5 4 1 1 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 RJW66886.1 - 0.00037 20.0 5.7 0.094 12.2 0.1 3.5 3 1 0 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 RJW66886.1 - 0.09 13.4 15.8 1.2 10.0 2.5 6.4 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 RJW66886.1 - 0.15 12.2 13.3 20 5.6 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich repeat Ank_4 PF13637.6 RJW66887.1 - 5.8e-17 61.8 0.3 2.1e-10 40.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW66887.1 - 1.9e-13 50.8 0.1 3.2e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW66887.1 - 3.1e-13 49.7 0.2 8.3e-06 26.0 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RJW66887.1 - 7.6e-13 48.3 0.6 3e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RJW66887.1 - 1.6e-11 43.3 0.1 1.6e-05 24.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat PepSY PF03413.19 RJW66887.1 - 0.12 12.9 0.3 1.7 9.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain 4F5 PF04419.14 RJW66887.1 - 0.36 11.7 6.6 0.69 10.8 6.6 1.4 1 0 0 1 1 1 0 4F5 protein family 3-alpha PF03475.14 RJW66889.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 3-alpha domain Collagen PF01391.18 RJW66892.1 - 8.7e-156 505.8 602.4 7.2e-10 38.5 23.2 20.5 2 1 14 16 16 16 14 Collagen triple helix repeat (20 copies) COLFI PF01410.18 RJW66892.1 - 1.7e-25 89.7 0.0 6.2e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 Fibrillar collagen C-terminal domain Laminin_G_3 PF13385.6 RJW66892.1 - 0.00014 22.0 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily BTB_2 PF02214.22 RJW66893.1 - 4.8e-11 42.9 0.0 9.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 RJW66893.1 - 0.95 10.5 2.8 3 8.9 0.3 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat LRR_9 PF14580.6 RJW66895.1 - 1.7e-68 229.5 0.3 3e-68 228.7 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RJW66895.1 - 1.2e-05 25.0 4.5 0.00011 21.9 2.3 2.8 1 1 1 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 RJW66895.1 - 0.00099 19.5 8.1 0.06 13.8 1.2 3.2 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) SUIM_assoc PF16619.5 RJW66895.1 - 1.4 9.0 6.8 3.1 8.0 6.8 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Herpes_capsid PF06112.11 RJW66898.1 - 0.37 10.8 4.4 0.22 11.6 0.4 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein HLH PF00010.26 RJW66899.1 - 9.5e-14 51.1 1.2 2e-13 50.1 1.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DASH_Dad4 PF08650.10 RJW66900.1 - 0.046 13.7 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad4 Latrotoxin_C PF15658.6 RJW66900.1 - 0.1 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Latrotoxin C-terminal domain DnaJ_C PF01556.18 RJW66901.1 - 2.1e-33 115.5 0.0 3e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RJW66901.1 - 1.2e-25 89.4 2.3 1.9e-25 88.8 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 RJW66901.1 - 0.0048 16.9 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Pam16 Neisseria_TspB PF05616.13 RJW66903.1 - 0.2 10.1 0.2 0.27 9.7 0.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RVT_1 PF00078.27 RJW66904.1 - 4.9e-46 157.0 0.0 8.9e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_9 PF16293.5 RJW66904.1 - 1.2 9.0 12.6 2.3 8.1 0.0 5.3 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 RJW66904.1 - 5.9 6.8 9.9 14 5.5 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Docking PF08990.11 RJW66906.1 - 0.14 11.8 6.1 0.84 9.3 2.8 3.2 2 0 0 2 2 2 0 Erythronolide synthase docking PLAC9 PF15205.6 RJW66906.1 - 0.36 11.3 2.9 0.71 10.3 0.7 2.7 2 0 0 2 2 2 0 Placenta-specific protein 9 zf-C2H2 PF00096.26 RJW66907.1 - 2.8e-19 68.4 37.1 9.9e-05 22.6 1.0 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW66907.1 - 1.3e-14 53.6 34.9 0.00069 20.3 0.2 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW66907.1 - 2.1e-11 43.7 29.0 0.13 12.8 3.4 6.7 6 1 0 6 6 6 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW66907.1 - 3.4e-06 26.9 24.7 0.15 12.1 1.3 6.3 5 2 1 6 6 6 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW66907.1 - 1.2e-05 24.9 3.2 0.0022 17.7 0.0 4.4 4 0 0 4 4 4 2 zinc-finger C2H2-type zf_UBZ PF18439.1 RJW66907.1 - 1.5e-05 24.4 8.0 0.98 9.1 0.0 4.6 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 RJW66907.1 - 5.9e-05 22.9 15.4 0.065 13.2 0.2 4.6 4 0 0 4 4 4 2 zinc-finger of a C2HC-type DUF1644 PF07800.12 RJW66907.1 - 0.00072 19.7 14.2 0.03 14.4 5.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1644) FYVE PF01363.21 RJW66907.1 - 0.0015 18.6 18.0 0.17 12.0 1.5 3.6 2 1 1 3 3 3 2 FYVE zinc finger zf-C2H2_3rep PF18868.1 RJW66907.1 - 0.0036 18.0 16.0 3.2 8.5 0.7 4.5 1 1 3 5 5 5 2 Zinc finger C2H2-type, 3 repeats DZR PF12773.7 RJW66907.1 - 0.0037 17.3 12.3 0.089 12.8 6.3 3.1 1 1 2 3 3 3 2 Double zinc ribbon zf-Di19 PF05605.12 RJW66907.1 - 0.0041 17.4 17.5 0.06 13.7 2.3 3.7 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RJW66907.1 - 0.0074 16.6 14.2 1.2 9.6 0.1 5.0 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RJW66907.1 - 0.019 15.3 17.6 0.16 12.3 2.5 4.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 RJW66907.1 - 0.031 14.2 9.5 0.16 12.0 1.0 3.6 3 1 0 3 3 3 0 Adenylate kinase, active site lid TFIID_NTD2 PF04494.15 RJW66907.1 - 0.043 14.0 0.1 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain Ta0938 PF11494.8 RJW66907.1 - 0.056 13.7 0.1 0.65 10.3 0.0 2.5 1 1 1 2 2 2 0 Ta0938 Rad50_zn_hook PF04423.14 RJW66907.1 - 0.062 13.2 1.0 4.2 7.3 0.1 3.0 2 0 0 2 2 2 0 Rad50 zinc hook motif XPA_N PF01286.18 RJW66907.1 - 0.064 13.3 15.2 1.2 9.3 0.2 4.9 5 0 0 5 5 5 0 XPA protein N-terminal zinc-ribbons_6 PF07191.12 RJW66907.1 - 0.065 13.2 13.2 3.5 7.7 0.4 4.1 2 2 0 2 2 2 0 zinc-ribbons zf-C2H2_12 PF18658.1 RJW66907.1 - 0.075 12.6 17.5 0.12 11.9 0.2 4.4 2 2 2 4 4 4 0 Zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 RJW66907.1 - 0.1 12.7 18.9 20 5.4 0.4 5.0 4 1 1 5 5 5 0 Zinc ribbon domain YhfH PF14149.6 RJW66907.1 - 0.68 10.0 12.2 2.8 8.0 3.1 3.7 2 1 1 3 3 3 0 YhfH-like protein DUF2256 PF10013.9 RJW66907.1 - 1 9.5 11.9 25 5.1 0.0 4.9 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_9 PF14369.6 RJW66907.1 - 1.1 9.6 9.9 5.4 7.4 0.3 3.9 3 1 1 4 4 4 0 zinc-ribbon zf_C2H2_ZHX PF18387.1 RJW66907.1 - 1.2 8.8 5.8 7.1 6.3 0.0 3.5 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 RJW66907.1 - 2.5 8.0 8.1 20 5.1 0.0 4.2 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) DUF629 PF04780.12 RJW66907.1 - 8.1 4.8 13.7 0.14 10.6 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF629) SH3_1 PF00018.28 RJW66908.1 - 1.4e-06 27.8 0.2 2.5e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_10 PF17902.1 RJW66908.1 - 0.00084 19.4 0.1 0.0019 18.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RJW66908.1 - 0.00097 19.0 0.1 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BicD PF09730.9 RJW66909.1 - 1.9e-102 344.0 58.3 1.9e-102 344.0 58.3 2.1 1 1 1 2 2 2 1 Microtubule-associated protein Bicaudal-D TPR_MLP1_2 PF07926.12 RJW66909.1 - 0.00011 22.2 18.4 0.00011 22.2 18.4 6.7 6 1 1 7 7 7 3 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 RJW66909.1 - 0.0067 16.7 1.1 0.0067 16.7 1.1 6.6 4 2 2 6 6 6 2 Autophagy protein 16 (ATG16) APG6_N PF17675.1 RJW66909.1 - 0.016 15.7 3.3 0.016 15.7 3.3 7.2 4 1 3 7 7 7 0 Apg6 coiled-coil region Gag_p17 PF00540.18 RJW66909.1 - 0.063 13.3 0.1 0.063 13.3 0.1 2.7 3 0 0 3 3 3 0 gag gene protein p17 (matrix protein) SURF6 PF04935.12 RJW66910.1 - 2.4e-24 86.3 28.3 3.8e-24 85.6 28.3 1.3 1 0 0 1 1 1 1 Surfeit locus protein 6 rve PF00665.26 RJW66910.1 - 2.8e-07 30.7 0.2 1.8e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain SUIM_assoc PF16619.5 RJW66910.1 - 8 6.6 8.1 24 5.1 8.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 EXS PF03124.14 RJW66911.1 - 8.4e-90 301.4 18.5 1.3e-89 300.8 18.5 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.19 RJW66911.1 - 0.0017 18.3 0.8 0.0017 18.3 0.8 2.2 2 0 0 2 2 2 1 SPX domain DUF4079 PF13301.6 RJW66911.1 - 0.12 12.5 0.5 0.22 11.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Babuvirus_MP PF07234.11 RJW66911.1 - 1.9 8.7 4.6 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 Movement and RNA silencing protein AAA_6 PF12774.7 RJW66912.1 - 8.4e-161 534.4 0.0 3e-160 532.6 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW66912.1 - 4.6e-145 483.7 7.4 4.6e-145 483.7 7.4 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RJW66912.1 - 1.1e-80 270.7 0.1 1.7e-79 266.8 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RJW66912.1 - 2.1e-80 268.5 0.0 6.8e-78 260.3 0.0 3.4 4 0 0 4 4 4 1 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 RJW66912.1 - 1.1e-27 96.6 0.0 5.6e-27 94.4 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RJW66912.1 - 3.6e-19 68.8 0.1 1.5e-18 66.8 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RJW66912.1 - 1.6e-17 63.8 0.0 0.0015 18.5 0.0 5.9 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 RJW66912.1 - 1.6e-06 28.6 0.0 1.7 9.1 0.1 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW66912.1 - 0.0013 19.2 2.2 8.7 6.7 0.0 5.5 5 1 0 5 5 5 1 AAA ATPase domain RNA_helicase PF00910.22 RJW66912.1 - 0.0016 18.8 0.0 3.8 7.9 0.0 3.7 4 0 0 4 4 3 1 RNA helicase AAA_18 PF13238.6 RJW66912.1 - 0.0044 17.6 0.3 0.042 14.4 0.0 3.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 RJW66912.1 - 0.083 12.6 0.1 2.1 8.0 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 RJW66912.1 - 0.094 12.3 0.1 13 5.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain PB1 PF00564.24 RJW66912.1 - 0.11 12.4 0.0 2.4 8.1 0.0 2.7 2 0 0 2 2 2 0 PB1 domain AAA_22 PF13401.6 RJW66912.1 - 0.12 12.6 5.8 48 4.2 0.0 5.8 8 0 0 8 8 6 0 AAA domain Slu7 PF11708.8 RJW66913.1 - 4.2e-101 338.2 3.1 4.2e-101 338.2 3.1 3.9 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 RJW66913.1 - 0.081 12.7 0.5 0.16 11.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 RJW66913.1 - 0.7 10.1 3.3 1.5 9.0 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Pneumo_att_G PF05539.11 RJW66913.1 - 5.4 6.5 13.9 7.5 6.0 13.9 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF4200 PF13863.6 RJW66915.1 - 5.5e-07 30.0 12.1 5.5e-07 30.0 12.1 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) DUF2529 PF10740.9 RJW66915.1 - 0.045 13.4 0.4 0.094 12.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) FapA PF03961.13 RJW66915.1 - 8.7 4.8 12.7 0.16 10.5 3.3 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Beach PF02138.18 RJW66919.1 - 4.4e-123 410.0 0.2 6.7e-123 409.5 0.2 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 RJW66919.1 - 3.7e-11 43.0 0.0 8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 RJW66919.1 - 2.2e-09 37.8 3.7 0.0017 19.1 0.1 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4800 PF16057.5 RJW66919.1 - 0.00052 19.4 0.1 0.00095 18.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) DUF1088 PF06469.11 RJW66919.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) Tmemb_161AB PF10268.9 RJW66920.1 - 3.3e-60 204.1 0.6 4.1e-60 203.8 0.6 1.1 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Asp PF00026.23 RJW66921.1 - 7.4e-32 111.0 0.0 8.4e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW66921.1 - 0.0073 16.1 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal DDT PF02791.17 RJW66921.1 - 0.12 12.7 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 DDT domain PhoLip_ATPase_C PF16212.5 RJW66922.1 - 1.7e-18 67.3 0.2 1.9e-18 67.2 0.2 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal TMPIT PF07851.13 RJW66923.1 - 3e-109 365.2 9.5 3.7e-109 364.9 9.5 1.0 1 0 0 1 1 1 1 TMPIT-like protein Peptidase_M26_N PF05342.14 RJW66923.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region Integrase_H2C2 PF17921.1 RJW66924.1 - 2.7e-13 49.8 0.0 5.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RJW66924.1 - 1.3e-11 44.7 0.0 2.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RJW66924.1 - 3.5e-06 27.1 0.1 9.5e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 RJW66924.1 - 0.045 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain ELM2 PF01448.24 RJW66925.1 - 6.7e-09 36.4 0.0 2.3e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 RJW66925.1 - 6.5e-07 29.4 0.0 0.00013 22.1 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RJW66925.1 - 0.00028 20.7 0.1 0.077 12.9 0.0 2.6 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 RJW66925.1 - 0.013 15.8 0.1 0.062 13.6 0.0 2.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain Pkinase PF00069.25 RJW66927.1 - 1e-75 254.5 0.0 1.5e-75 254.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66927.1 - 1.6e-43 148.8 0.0 2.3e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 RJW66927.1 - 4.2e-13 49.8 0.1 1.7e-12 47.8 0.1 2.1 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 RJW66927.1 - 2.5e-09 36.9 0.0 3.8e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RJW66927.1 - 0.00034 20.3 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 RJW66927.1 - 0.00083 18.4 0.1 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RJW66927.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 RJW66927.1 - 0.019 13.8 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 RJW66927.1 - 0.042 13.8 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DHHC PF01529.20 RJW66929.1 - 8.5e-34 116.5 17.0 8.5e-34 116.5 17.0 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DASH_Dam1 PF08653.10 RJW66930.1 - 0.1 12.4 0.4 0.18 11.7 0.4 1.4 1 1 0 1 1 1 0 DASH complex subunit Dam1 E1-E2_ATPase PF00122.20 RJW66931.1 - 9.7e-24 83.9 0.0 2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 RJW66931.1 - 1.1e-13 52.0 0.0 9e-08 32.7 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RJW66931.1 - 0.0005 20.1 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Dynein_C PF18199.1 RJW66934.1 - 4.3e-114 380.9 0.0 2.1e-113 378.6 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RJW66934.1 - 7.8e-90 299.8 0.2 7.8e-90 299.8 0.2 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 RJW66934.1 - 6.9e-60 201.6 0.0 3.7e-59 199.2 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RJW66934.1 - 1.2e-47 160.9 0.0 7.6e-44 148.6 0.0 2.9 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RJW66934.1 - 2.1e-42 145.4 3.5 2.1e-42 145.4 3.5 1.9 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 RJW66934.1 - 1.3e-11 44.4 0.6 2.4e-11 43.5 0.6 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Spc7 PF08317.11 RJW66934.1 - 0.0016 17.4 5.9 0.0016 17.4 5.9 3.1 3 0 0 3 3 3 1 Spc7 kinetochore protein DHR10 PF18595.1 RJW66934.1 - 0.0026 17.8 6.7 0.0026 17.8 6.7 3.8 4 1 1 5 5 5 1 Designed helical repeat protein 10 domain SKA2 PF16740.5 RJW66934.1 - 0.01 15.6 2.7 0.062 13.1 2.7 2.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 HSBP1 PF06825.12 RJW66934.1 - 0.084 12.7 1.9 0.26 11.2 1.9 1.9 1 0 0 1 1 1 0 Heat shock factor binding protein 1 NPV_P10 PF05531.12 RJW66934.1 - 0.19 12.2 1.5 0.87 10.1 1.5 2.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 RJW66934.1 - 0.98 10.0 7.2 3.7 8.2 1.3 3.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4795 PF16043.5 RJW66934.1 - 2.8 7.5 12.0 0.04 13.5 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) AAA_23 PF13476.6 RJW66934.1 - 3.2 8.2 5.3 16 5.9 1.6 2.7 2 0 0 2 2 2 0 AAA domain PEARLI-4 PF05278.12 RJW66934.1 - 3.4 7.2 11.9 0.07 12.7 4.8 1.7 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Fez1 PF06818.15 RJW66934.1 - 7.5 7.0 17.3 0.89 10.0 3.0 3.2 3 0 0 3 3 3 0 Fez1 7tm_1 PF00001.21 RJW66935.1 - 8.8e-21 74.4 11.4 1.2e-20 73.9 11.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW66935.1 - 6.5e-14 51.9 27.4 1.9e-07 30.7 2.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw CPBP PF02517.16 RJW66935.1 - 0.15 12.5 0.0 0.15 12.5 0.0 3.5 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease Claudin_2 PF13903.6 RJW66935.1 - 6.1 6.6 13.7 0.19 11.5 4.4 2.8 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction MULE PF10551.9 RJW66936.1 - 9.5e-08 32.4 0.0 2.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain LRR_6 PF13516.6 RJW66938.1 - 2.9e-06 26.9 22.2 0.071 13.2 0.9 7.0 8 0 0 8 8 8 4 Leucine Rich repeat Armet PF10208.9 RJW66938.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding RVT_1 PF00078.27 RJW66940.1 - 0.041 13.4 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) LicD PF04991.13 RJW66941.1 - 9e-10 39.1 0.1 1.6e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 LicD family cNMP_binding PF00027.29 RJW66942.1 - 3.5e-37 126.4 0.1 3.7e-17 62.2 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 RJW66942.1 - 1.6e-05 24.4 0.1 4.6e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain DUF4618 PF15397.6 RJW66942.1 - 0.0054 16.2 2.0 0.026 14.0 1.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) LicD PF04991.13 RJW66943.1 - 1.2e-09 38.7 4.9 8.5e-09 35.9 3.4 2.3 1 1 1 2 2 2 1 LicD family COQ7 PF03232.13 RJW66945.1 - 1.1e-53 181.5 0.1 1.2e-53 181.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF4677 PF15726.5 RJW66945.1 - 0.078 13.1 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Lipase_GDSL PF00657.22 RJW66945.1 - 0.18 11.7 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 RJW66946.1 - 5.1e-39 134.2 35.2 5.8e-39 134.0 35.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RJW66946.1 - 1.1e-10 40.9 7.3 1.1e-10 40.9 7.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 RJW66946.1 - 4.7e-10 38.4 26.3 2.9e-05 22.6 3.8 4.1 1 1 3 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 RJW66946.1 - 1.9e-06 26.7 3.7 1.9e-06 26.7 3.7 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein COBRA1 PF06209.13 RJW66947.1 - 1.6e-27 96.6 2.4 1.8e-11 43.6 0.4 3.2 3 0 0 3 3 3 3 Cofactor of BRCA1 (COBRA1) RsdA_SigD_bd PF16751.5 RJW66947.1 - 0.74 10.1 5.0 15 5.9 0.0 3.6 4 0 0 4 4 4 0 Anti-sigma-D factor RsdA to sigma factor binding region TM2 PF05154.16 RJW66949.1 - 1.2e-16 60.7 8.8 2.3e-16 59.8 8.8 1.4 1 0 0 1 1 1 1 TM2 domain His_Me_b4a2 PF18275.1 RJW66949.1 - 0.095 12.8 0.4 0.21 11.7 0.4 1.5 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain HD_3 PF13023.6 RJW66950.1 - 1.9e-48 164.5 0.1 2.4e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 RJW66950.1 - 9.4e-14 51.6 0.0 1.3e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme QIL1 PF15884.5 RJW66950.1 - 0.0035 17.9 0.0 0.014 16.0 0.0 1.9 2 0 0 2 2 2 1 MICOS complex subunit MIC13, QIL1 HD PF01966.22 RJW66950.1 - 0.034 14.4 0.0 0.066 13.4 0.0 1.5 1 1 0 1 1 1 0 HD domain Plus-3 PF03126.18 RJW66950.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Plus-3 domain Glyco_hydro_65m PF03632.15 RJW66951.1 - 5.7e-50 170.3 0.2 6e-22 78.0 0.4 3.1 1 1 2 3 3 3 3 Glycosyl hydrolase family 65 central catalytic domain TPR_1 PF00515.28 RJW66951.1 - 0.095 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CIAPIN1 PF05093.13 RJW66952.1 - 3.7e-23 81.9 13.6 5.4e-18 65.3 2.9 2.5 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 RJW66952.1 - 0.0059 16.9 0.0 0.0094 16.2 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Neuro_bHLH PF12533.8 RJW66953.1 - 0.035 15.3 0.8 2.2 9.5 0.4 2.3 1 1 1 2 2 2 0 Neuronal helix-loop-helix transcription factor Nipped-B_C PF12830.7 RJW66955.1 - 2.8e-67 226.3 6.3 2.6e-66 223.2 0.3 3.7 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus RVT_1 PF00078.27 RJW66955.1 - 9.9e-40 136.4 0.0 3.7e-39 134.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cohesin_HEAT PF12765.7 RJW66955.1 - 3.3e-10 40.1 5.9 3.4e-10 40.0 2.6 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 RJW66955.1 - 3e-09 37.1 5.0 0.024 14.7 0.3 4.6 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RJW66955.1 - 0.00068 19.7 7.2 2.3 8.7 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 RJW66955.1 - 0.0052 17.2 0.7 0.0052 17.2 0.7 4.9 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 RJW66955.1 - 0.075 13.6 0.9 0.87 10.2 0.7 3.2 1 1 0 1 1 1 0 HEAT-like repeat AAA_6 PF12774.7 RJW66957.1 - 3.9e-160 532.2 0.0 3.7e-158 525.7 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW66957.1 - 7.3e-142 473.2 4.2 7.3e-142 473.2 4.2 2.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 RJW66957.1 - 3.7e-79 264.4 0.1 9.4e-77 256.6 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_8 PF12780.7 RJW66957.1 - 7.8e-78 261.4 0.3 3.4e-77 259.3 0.0 2.4 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 Dynein_AAA_lid PF17852.1 RJW66957.1 - 1e-35 122.6 0.2 3.5e-35 120.9 0.2 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RJW66957.1 - 7.3e-20 71.4 0.0 6.4e-08 32.7 0.0 5.9 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RJW66957.1 - 1.1e-16 60.9 0.3 5.7e-16 58.6 0.2 2.4 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 RJW66957.1 - 3.1e-06 27.7 0.0 0.051 14.0 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RJW66957.1 - 2.5e-05 24.6 0.2 0.63 10.3 0.0 4.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 RJW66957.1 - 0.0002 21.8 0.2 6.4 7.1 0.0 5.1 5 0 0 5 5 5 1 AAA ATPase domain SRPRB PF09439.10 RJW66957.1 - 0.00041 19.8 0.1 0.088 12.2 0.0 3.2 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 RJW66957.1 - 0.00047 20.7 0.5 0.81 10.2 0.0 4.6 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 RJW66957.1 - 0.00063 20.1 0.1 1.2 9.6 0.0 3.9 3 0 0 3 3 3 1 RNA helicase Mg_chelatase PF01078.21 RJW66957.1 - 0.0043 16.5 0.9 4.8 6.5 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 RJW66957.1 - 0.0075 15.4 0.5 0.036 13.1 0.0 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_24 PF13479.6 RJW66957.1 - 0.013 15.3 0.1 28 4.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 RJW66957.1 - 0.014 15.6 0.0 26 5.0 0.0 4.0 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 RJW66957.1 - 0.034 13.5 0.1 5.2 6.4 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein AAA_30 PF13604.6 RJW66957.1 - 0.057 13.1 1.3 2.9 7.6 0.1 2.8 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 RJW66957.1 - 0.1 12.3 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Kindlin_2_N PF18124.1 RJW66957.1 - 0.56 10.4 3.6 18 5.6 0.0 3.1 3 0 0 3 3 2 0 Kindlin-2 N-terminal domain FERM_M PF00373.18 RJW66959.1 - 4.8e-20 72.1 0.0 8.4e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 RJW66959.1 - 2.6e-17 63.0 0.0 6.9e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 RJW66959.1 - 9.3e-10 38.3 0.0 2.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain zf-C3H2C3 PF17122.5 RJW66960.1 - 0.038 14.0 3.3 0.11 12.5 3.3 1.9 1 0 0 1 1 1 0 Zinc-finger CAP PF00188.26 RJW66962.1 - 1e-22 81.3 0.3 1.7e-22 80.6 0.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Kinesin PF00225.23 RJW66963.1 - 5e-33 114.4 0.3 1.5e-20 73.4 0.0 3.3 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 RJW66963.1 - 6.2e-21 74.9 0.2 7.4e-20 71.4 0.0 2.8 3 0 0 3 3 3 1 Microtubule binding PBECR1 PF18809.1 RJW66963.1 - 7.3 7.3 8.1 1.8 9.3 4.0 2.1 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 BrkDBD PF09607.10 RJW66964.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Brinker DNA-binding domain TPT PF03151.16 RJW66965.1 - 1.9e-14 53.7 20.0 2.5e-14 53.3 20.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RJW66965.1 - 0.26 11.5 35.2 0.025 14.8 13.8 2.3 2 0 0 2 2 2 0 EamA-like transporter family V-ATPase_G_2 PF16999.5 RJW66967.1 - 0.73 10.3 4.5 1.1 9.7 4.5 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Retrotrans_gag PF03732.17 RJW66968.1 - 0.034 14.4 0.9 0.092 13.0 0.9 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Tup_N PF08581.10 RJW66968.1 - 0.058 13.7 11.9 0.053 13.8 4.7 2.9 3 0 0 3 3 3 0 Tup N-terminal DUF334 PF03904.13 RJW66968.1 - 0.23 10.9 9.1 0.4 10.2 9.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF334) MIF4G_like_2 PF09090.11 RJW66968.1 - 0.37 10.2 6.8 0.65 9.4 6.8 1.4 1 0 0 1 1 1 0 MIF4G like Exonuc_VII_L PF02601.15 RJW66968.1 - 0.9 9.0 5.6 1.2 8.6 5.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit EMP24_GP25L PF01105.24 RJW66968.1 - 1.4 8.8 8.2 1.2 9.1 0.8 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4407 PF14362.6 RJW66968.1 - 3.3 7.0 9.0 6 6.1 9.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GCP_C_terminal PF04130.13 RJW66970.1 - 4.7e-76 256.2 5.6 4.7e-76 256.2 5.6 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 RJW66970.1 - 1.4e-60 205.5 0.0 2.3e-60 204.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF1325 PF07039.11 RJW66973.1 - 0.12 12.5 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 SGF29 tudor-like domain Tex_N PF09371.10 RJW66974.1 - 1e-23 83.9 0.0 1.2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Glyco_hydro_15 PF00723.21 RJW66974.1 - 0.02 13.7 0.0 0.024 13.4 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 NOG1 PF06858.14 RJW66975.1 - 2.5e-25 88.0 0.1 4.6e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 RJW66975.1 - 1.4e-16 60.2 0.3 1.4e-16 60.2 0.3 2.1 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 RJW66975.1 - 2.9e-08 33.8 0.0 6.7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RJW66975.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B YjbH PF06082.11 RJW66975.1 - 0.53 9.0 1.9 0.79 8.5 1.9 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH WD40 PF00400.32 RJW66976.1 - 2.6e-06 28.0 2.1 0.0053 17.6 0.0 4.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.8 RJW66976.1 - 0.03 13.0 0.4 0.14 10.7 0.0 2.1 3 0 0 3 3 3 0 Nucleoporin Nup120/160 COX5B PF01215.19 RJW66976.1 - 0.059 13.1 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb Pkinase PF00069.25 RJW66978.1 - 1.3e-31 109.9 0.0 2e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW66978.1 - 3.9e-20 72.2 0.0 5.8e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW66978.1 - 0.0028 17.6 0.0 0.092 12.7 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family PIP49_C PF12260.8 RJW66978.1 - 0.045 13.4 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 SelP_N PF04592.14 RJW66978.1 - 2.5 7.4 10.8 5.3 6.4 10.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Frtz PF11768.8 RJW66980.1 - 0.061 11.6 0.0 0.091 11.1 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz UQ_con PF00179.26 RJW66981.1 - 1.5e-41 141.4 0.4 1.6e-41 141.2 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RJW66981.1 - 6.1e-05 22.7 0.0 7.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RJW66981.1 - 0.0022 18.2 0.6 0.003 17.8 0.6 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 RJW66981.1 - 0.0033 17.3 0.5 0.0069 16.2 0.4 1.6 1 1 0 1 1 1 1 UEV domain GIY-YIG PF01541.24 RJW66982.1 - 3e-12 46.7 0.0 6.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain RT_RNaseH_2 PF17919.1 RJW66982.1 - 1.2e-06 28.5 0.1 1.8e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-ANAPC11 PF12861.7 RJW66982.1 - 0.073 13.1 1.4 0.14 12.2 0.4 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger MCRS_N PF13325.6 RJW66983.1 - 1.1e-20 74.4 0.8 2.1e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal region of micro-spherule protein RVT_1 PF00078.27 RJW66983.1 - 2.5e-05 23.9 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FHA PF00498.26 RJW66983.1 - 0.0021 18.3 0.0 0.0053 17.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain WD40 PF00400.32 RJW66985.1 - 4.4e-15 55.8 1.3 0.16 12.9 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW66985.1 - 0.026 14.8 0.0 33 4.9 0.0 4.2 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 RJW66988.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_32 PF13679.6 RJW66989.1 - 6.1e-18 65.3 0.2 1.6e-16 60.7 0.3 2.3 2 1 0 2 2 2 1 Methyltransferase domain DUF5560 PF17715.1 RJW66989.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5560) zf-HIT PF04438.16 RJW66990.1 - 1.4e-06 28.1 12.4 2e-06 27.6 12.4 1.3 1 0 0 1 1 1 1 HIT zinc finger Toxin_38 PF14866.6 RJW66990.1 - 0.5 10.7 7.9 0.84 10.0 7.9 1.3 1 0 0 1 1 1 0 Potassium channel toxin zf-MYND PF01753.18 RJW66990.1 - 0.6 10.2 8.1 1 9.5 8.1 1.3 1 0 0 1 1 1 0 MYND finger DUF4131 PF13567.6 RJW66992.1 - 0.059 13.0 0.0 0.25 11.0 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WD40 PF00400.32 RJW66994.1 - 9.2e-10 39.0 9.8 0.0013 19.5 0.4 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW66994.1 - 5.8e-07 29.7 0.1 0.051 13.9 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain bZIP_2 PF07716.15 RJW66995.1 - 6.8e-09 35.7 10.0 6.8e-09 35.7 10.0 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 RJW66995.1 - 9.7e-06 25.6 9.9 1.4e-05 25.1 8.9 1.9 1 1 1 2 2 2 1 bZIP transcription factor DUF3450 PF11932.8 RJW66995.1 - 0.032 13.5 5.6 0.046 13.0 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_Maf PF03131.17 RJW66995.1 - 0.071 13.6 8.7 0.13 12.8 8.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor PAP2 PF01569.21 RJW66998.1 - 4.1e-20 71.9 4.3 6.6e-20 71.3 4.3 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 RJW66998.1 - 0.00021 21.8 1.0 0.00021 21.8 1.0 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 RJW66998.1 - 0.04 13.6 8.2 0.15 11.8 8.2 1.9 1 1 0 1 1 1 0 PAP2 superfamily TMEM173 PF15009.6 RJW66998.1 - 0.1 11.7 2.9 0.051 12.7 0.4 1.6 2 0 0 2 2 2 0 Transmembrane protein 173 RRM_1 PF00076.22 RJW67000.1 - 2.8e-30 103.9 0.1 3.2e-16 58.9 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer PF06495.11 RJW67000.1 - 2.2e-07 31.2 20.4 3.5e-07 30.5 20.4 1.2 1 0 0 1 1 1 1 Fruit fly transformer protein RRM_7 PF16367.5 RJW67000.1 - 0.00034 20.7 0.0 0.018 15.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif SAE2 PF08573.10 RJW67000.1 - 0.014 16.5 6.5 0.027 15.6 6.5 1.5 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus NPR3 PF03666.13 RJW67000.1 - 0.41 9.4 4.3 0.7 8.6 4.3 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 RJW67000.1 - 0.81 8.5 6.3 1.1 8.0 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 RJW67000.1 - 1.6 8.7 8.1 2.6 8.0 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PRP38_assoc PF12871.7 RJW67000.1 - 1.9 9.1 48.4 4.5 7.9 48.4 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term CDC45 PF02724.14 RJW67000.1 - 8.4 4.5 17.3 12 4.1 17.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Xpo1 PF08389.12 RJW67001.1 - 7e-09 35.9 10.1 2.8e-08 33.9 1.9 4.5 4 0 0 4 4 4 2 Exportin 1-like protein ORC4_C PF14629.6 RJW67002.1 - 2.7e-27 95.6 0.0 4.5e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 RJW67002.1 - 0.0008 19.8 0.8 0.018 15.4 0.5 2.6 2 1 0 2 2 2 1 AAA ATPase domain Ets PF00178.22 RJW67003.1 - 4.1e-37 126.5 0.4 7.1e-37 125.7 0.4 1.4 1 0 0 1 1 1 1 Ets-domain Prefoldin PF02996.17 RJW67004.1 - 8.2e-14 51.5 0.6 1.4e-13 50.8 0.6 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 RJW67004.1 - 0.045 13.8 2.2 0.046 13.8 0.2 2.1 2 1 0 2 2 2 0 Prefoldin subunit FliD_N PF02465.18 RJW67004.1 - 2.9 8.7 5.1 15 6.4 0.1 2.7 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus MyTH4 PF00784.17 RJW67005.1 - 2.3e-57 192.1 0.0 2.6e-31 108.3 0.0 3.0 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 RJW67005.1 - 5.8e-14 52.5 0.0 1.1e-08 35.4 0.0 3.5 3 1 0 3 3 3 2 FERM central domain IQ PF00612.27 RJW67005.1 - 6.6e-06 25.5 4.6 0.044 13.6 0.4 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif N_NLPC_P60 PF12912.7 RJW67005.1 - 3e-05 24.4 0.2 0.00034 20.9 0.0 2.7 3 0 0 3 3 3 1 NLPC_P60 stabilising domain, N term SH3_2 PF07653.17 RJW67005.1 - 0.00023 20.8 0.1 0.0013 18.4 0.1 2.2 1 1 0 1 1 1 1 Variant SH3 domain FERM_N PF09379.10 RJW67005.1 - 0.00047 20.0 0.0 0.055 13.4 0.0 2.5 2 0 0 2 2 2 1 FERM N-terminal domain SH3_9 PF14604.6 RJW67005.1 - 0.0049 16.7 0.4 0.051 13.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain RA PF00788.23 RJW67005.1 - 0.042 14.5 0.0 0.16 12.6 0.0 2.0 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 RJW67005.1 - 0.18 11.4 0.0 0.61 9.7 0.0 1.9 1 0 0 1 1 1 0 SH3 domain Pkinase_Tyr PF07714.17 RJW67007.1 - 3e-59 200.4 0.0 6.3e-59 199.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_3 PF13927.6 RJW67007.1 - 3.5e-56 187.7 5.8 1.6e-08 35.1 0.0 8.6 7 1 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 RJW67007.1 - 4.1e-54 180.6 0.0 5.4e-08 32.8 0.0 8.4 8 0 0 8 8 8 7 Immunoglobulin I-set domain ig PF00047.25 RJW67007.1 - 5.8e-37 125.7 1.4 1.3e-06 28.5 0.0 8.2 7 1 0 7 7 7 5 Immunoglobulin domain Ig_2 PF13895.6 RJW67007.1 - 2.9e-34 117.3 2.0 2.3e-07 31.0 0.0 8.3 8 0 0 8 8 8 5 Immunoglobulin domain Pkinase PF00069.25 RJW67007.1 - 6.5e-28 97.8 0.0 1.8e-27 96.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain V-set PF07686.17 RJW67007.1 - 3.9e-19 68.8 8.0 1.6 9.0 0.0 11.4 8 4 3 11 11 11 7 Immunoglobulin V-set domain Izumo-Ig PF16706.5 RJW67007.1 - 9e-07 28.9 2.0 0.12 12.5 0.0 6.2 7 1 0 7 7 7 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RJW67007.1 - 2e-06 27.2 0.0 3.6 7.2 0.0 4.9 5 1 0 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.12 RJW67007.1 - 6.1e-05 23.0 3.9 0.35 10.9 0.1 4.8 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 RJW67007.1 - 0.014 15.7 1.8 20 5.5 0.0 4.8 6 0 0 6 6 5 0 T-cell surface glycoprotein CD3 delta chain V-set_2 PF15910.5 RJW67007.1 - 0.018 15.1 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 ICOS V-set domain 7tm_2 PF00002.24 RJW67007.1 - 0.26 10.5 1.5 0.39 10.0 1.5 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) RRM_1 PF00076.22 RJW67008.1 - 7.9e-09 35.2 0.0 0.0059 16.4 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARL6IP6 PF15062.6 RJW67009.1 - 0.12 12.6 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix TPR_MLP1_2 PF07926.12 RJW67013.1 - 0.0023 18.0 5.7 0.0079 16.3 5.7 1.9 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF4588 PF15251.6 RJW67013.1 - 0.023 14.5 1.6 0.075 12.8 1.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) YabA PF06156.13 RJW67013.1 - 0.49 11.1 3.1 10 6.8 0.4 2.9 3 0 0 3 3 3 0 Initiation control protein YabA Filament PF00038.21 RJW67013.1 - 0.49 9.9 6.3 3.5 7.1 1.4 2.8 3 0 0 3 3 3 0 Intermediate filament protein Ion_trans_2 PF07885.16 RJW67014.1 - 6.2e-36 122.2 17.2 3.8e-19 68.4 4.2 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RJW67014.1 - 1.9e-07 30.6 11.1 0.00011 21.6 4.4 2.4 2 1 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 RJW67014.1 - 0.00038 20.3 0.8 0.0026 17.6 0.1 2.5 2 0 0 2 2 2 1 Ligand-gated ion channel BCD PF15461.6 RJW67014.1 - 0.0065 16.0 3.2 0.0089 15.6 0.2 2.2 2 0 0 2 2 2 1 Beta-carotene 15,15'-dioxygenase FA_desaturase PF00487.24 RJW67014.1 - 0.018 14.9 0.1 0.091 12.6 0.0 2.1 2 0 0 2 2 2 0 Fatty acid desaturase YlaC PF10777.9 RJW67014.1 - 0.028 14.3 0.2 2.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Inner membrane protein YlaC CobD_Cbib PF03186.13 RJW67014.1 - 0.15 11.3 0.2 0.85 8.8 0.0 2.1 2 0 0 2 2 2 0 CobD/Cbib protein EI24 PF07264.11 RJW67014.1 - 0.15 12.3 5.6 1.1 9.4 0.6 2.7 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) Popeye PF04831.13 RJW67014.1 - 0.17 12.1 4.6 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Popeye protein conserved region DUF3899 PF13038.6 RJW67014.1 - 5.3 7.6 7.1 2.6 8.6 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) MDM1 PF15501.6 RJW67015.1 - 1.1e-06 28.1 27.6 2.9e-06 26.7 27.6 1.7 1 1 0 1 1 1 1 Nuclear protein MDM1 Siah-Interact_N PF09032.11 RJW67015.1 - 0.037 14.3 1.5 0.14 12.5 1.5 2.0 1 0 0 1 1 1 0 Siah interacting protein, N terminal Spectrin PF00435.21 RJW67015.1 - 0.39 11.2 4.3 0.22 12.0 1.5 2.0 2 0 0 2 2 2 0 Spectrin repeat UNC-79 PF14776.6 RJW67017.1 - 0.0055 15.5 0.1 0.0087 14.9 0.1 1.3 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 Rap_GAP PF02145.15 RJW67018.1 - 1.8e-06 27.6 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 2 Rap/ran-GAP Homeodomain PF00046.29 RJW67019.1 - 1.8e-22 78.9 3.1 5.8e-22 77.3 2.6 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RJW67019.1 - 0.034 14.1 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain V-ATPase_H_N PF03224.14 RJW67019.1 - 0.087 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H EVI2A PF05399.11 RJW67019.1 - 1.5 8.4 5.7 0.56 9.8 2.8 1.7 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) RRM_1 PF00076.22 RJW67022.1 - 2.3e-17 62.6 0.0 4.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW67022.1 - 1.6e-05 24.5 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.6 RJW67022.1 - 0.00095 19.1 0.2 0.0019 18.2 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 RJW67022.1 - 0.0017 18.3 2.6 0.0017 18.3 2.6 1.6 2 0 0 2 2 2 1 Zinc knuckle NADH_oxidored PF08040.11 RJW67022.1 - 0.054 13.2 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 MNLL subunit zf-CCHC_6 PF15288.6 RJW67022.1 - 0.14 12.1 0.3 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle RRM_occluded PF16842.5 RJW67022.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_8 PF11835.8 RJW67022.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain Nop25 PF09805.9 RJW67023.1 - 5.3e-10 39.9 4.9 5.3e-10 39.9 4.9 1.7 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) Macoilin PF09726.9 RJW67023.1 - 0.025 13.1 1.0 0.039 12.5 1.0 1.3 1 0 0 1 1 1 0 Macoilin family RVT_1 PF00078.27 RJW67025.1 - 1.1e-33 116.7 0.0 1.8e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C15 PF01470.17 RJW67025.1 - 4.5e-15 56.3 0.0 7.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Pyroglutamyl peptidase Lectin_C PF00059.21 RJW67026.1 - 1.2e-06 29.1 0.6 2.4e-06 28.3 0.6 1.5 1 0 0 1 1 1 1 Lectin C-type domain Sushi PF00084.20 RJW67026.1 - 0.14 12.8 0.2 0.14 12.8 0.2 3.2 4 0 0 4 4 4 0 Sushi repeat (SCR repeat) Ras PF00071.22 RJW67028.1 - 3.1e-20 72.4 0.0 1.6e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RJW67028.1 - 0.019 15.1 0.0 0.044 14.0 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_M1 PF01433.20 RJW67029.1 - 1.6e-05 24.6 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RJW67029.1 - 0.019 15.2 0.0 0.05 13.8 0.0 1.7 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 RJW67029.1 - 0.069 13.5 0.1 3.2 8.2 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats PHTB1_N PF14727.6 RJW67030.1 - 3.4e-65 221.0 0.0 6.4e-65 220.1 0.0 1.4 2 0 0 2 2 2 1 PTHB1 N-terminus PHTB1_C PF14728.6 RJW67030.1 - 1.3e-09 37.6 0.1 2.7e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 PTHB1 C-terminus DHHC PF01529.20 RJW67032.1 - 5.4e-32 110.7 16.7 5.4e-32 110.7 16.7 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 RJW67032.1 - 3.7e-14 52.6 4.4 8.5e-06 25.9 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW67032.1 - 6.3e-13 49.1 0.7 3.9e-10 40.2 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW67032.1 - 6.3e-13 49.0 1.5 3.1e-06 27.6 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW67032.1 - 1.9e-12 46.2 1.4 0.0026 18.1 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RJW67032.1 - 3.7e-09 36.6 2.5 3.5e-05 24.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat DUF4239 PF14023.6 RJW67032.1 - 3 7.5 6.3 8.2 6.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) GSG-1 PF07803.11 RJW67033.1 - 0.0043 17.0 2.5 0.18 11.7 0.5 2.3 2 0 0 2 2 2 2 GSG1-like protein DUF2070 PF09843.9 RJW67033.1 - 0.61 8.3 9.6 0.67 8.2 9.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UPF0182 PF03699.13 RJW67033.1 - 1.7 6.7 10.0 2 6.4 10.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Claudin_2 PF13903.6 RJW67033.1 - 4.8 6.9 23.5 70 3.1 0.1 3.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction fn3 PF00041.21 RJW67034.1 - 4.6e-70 232.0 18.0 3.2e-10 40.2 0.0 14.4 12 4 0 12 12 12 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW67034.1 - 1.2e-27 96.3 6.0 0.00032 21.2 0.0 10.7 9 2 0 9 9 9 7 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RJW67034.1 - 1e-06 29.0 0.4 10 6.6 0.0 6.0 6 0 0 6 6 6 2 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 RJW67034.1 - 7.2e-05 23.1 0.0 42 4.5 0.0 6.3 7 0 0 7 7 7 1 Interferon-alpha/beta receptor, fibronectin type III tRNA_synthFbeta PF17759.1 RJW67036.1 - 6.8e-47 159.7 0.0 1e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 RJW67036.1 - 1.5e-27 95.6 0.0 3.3e-25 88.1 0.2 2.4 2 0 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 RJW67036.1 - 6.7e-21 74.7 0.1 2.7e-13 50.0 0.0 2.4 2 0 0 2 2 2 2 B3/4 domain B5 PF03484.15 RJW67036.1 - 1.3e-19 70.2 0.0 9.1e-17 61.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF772 PF05598.11 RJW67037.1 - 0.091 12.8 0.1 3 7.9 0.0 2.2 1 1 1 2 2 2 0 Transposase domain (DUF772) DUF4817 PF16087.5 RJW67038.1 - 1.8e-10 40.4 0.2 1.8e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) HTH_IclR PF09339.10 RJW67038.1 - 0.016 15.0 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF836 PF05768.14 RJW67039.1 - 0.076 13.4 0.2 0.16 12.4 0.2 1.7 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Ssl1 PF04056.14 RJW67041.1 - 2.5e-69 233.0 0.1 3.6e-69 232.4 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like DHHC PF01529.20 RJW67041.1 - 1.8e-32 112.2 11.8 1.8e-32 112.2 11.8 3.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 RJW67041.1 - 3.4e-25 88.1 3.4 6.2e-09 36.2 0.0 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW67041.1 - 7.1e-23 81.0 0.0 4.9e-13 49.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW67041.1 - 1.7e-22 79.1 6.3 9.7e-06 25.8 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW67041.1 - 8.2e-21 71.9 5.3 0.00044 20.5 0.0 6.3 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 RJW67041.1 - 1.5e-17 63.2 6.0 1.3e-06 28.6 0.3 5.8 5 0 0 5 5 5 3 Ankyrin repeat VWA_2 PF13519.6 RJW67041.1 - 3e-12 47.1 0.0 1.1e-11 45.3 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain MARVEL PF01284.23 RJW67041.1 - 2.5 8.1 23.5 0.65 10.0 1.3 3.6 3 2 1 4 4 4 0 Membrane-associating domain adh_short PF00106.25 RJW67042.1 - 3.5e-28 98.4 0.3 4.3e-12 45.9 0.0 3.0 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 RJW67042.1 - 3.2e-17 62.9 0.0 1.3e-11 44.6 0.0 2.9 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RJW67042.1 - 0.00071 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 RJW67042.1 - 0.00086 19.3 0.0 0.0028 17.6 0.0 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RJW67042.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Dak2 PF02734.17 RJW67044.1 - 0.051 13.5 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 DAK2 domain GTP_EFTU PF00009.27 RJW67045.1 - 1.6e-55 187.7 0.0 2.3e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 RJW67045.1 - 3.7e-36 123.5 0.0 6.7e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 RJW67045.1 - 3e-27 94.5 0.0 5.4e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II RVT_1 PF00078.27 RJW67045.1 - 9.5e-12 44.9 0.0 3.9e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) GTP_EFTU_D2 PF03144.25 RJW67045.1 - 8.4e-08 32.5 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RJW67045.1 - 3.6e-07 30.1 0.0 1.1e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain EFG_C PF00679.24 RJW67045.1 - 1.6e-06 28.0 0.0 9.8e-06 25.5 0.0 2.4 3 0 0 3 3 3 1 Elongation factor G C-terminus AIG1 PF04548.16 RJW67045.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AvrPtoB_bdg PF16847.5 RJW67045.1 - 0.032 14.7 0.0 0.077 13.5 0.0 1.5 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 RJW67045.1 - 0.06 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynein_heavy PF03028.15 RJW67045.1 - 0.17 12.0 0.1 0.45 10.6 0.1 1.7 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain DnaJ PF00226.31 RJW67047.1 - 1.5e-24 85.9 1.1 2.6e-24 85.1 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 RJW67047.1 - 2.4e-06 27.4 0.0 4.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 RJW67047.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family GWT1 PF06423.12 RJW67048.1 - 0.82 9.8 6.9 1.3 9.1 6.9 1.5 1 1 0 1 1 1 0 GWT1 CreD PF06123.12 RJW67048.1 - 4.5 5.9 8.1 5.8 5.6 8.1 1.1 1 0 0 1 1 1 0 Inner membrane protein CreD TAP_C PF03943.13 RJW67049.1 - 1e-17 63.5 0.5 2e-17 62.5 0.5 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_8 PF13855.6 RJW67049.1 - 0.021 14.6 1.1 0.44 10.3 1.6 2.4 2 0 0 2 2 2 0 Leucine rich repeat DUF2717 PF10911.8 RJW67050.1 - 0.049 13.3 0.1 6.6 6.5 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2717) ARID PF01388.21 RJW67053.1 - 3.9e-17 62.7 0.0 9.1e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RBB1NT PF08169.11 RJW67053.1 - 3.2e-08 33.6 0.0 1.2e-07 31.8 0.0 2.1 1 0 0 1 1 1 1 RBB1NT (NUC162) domain Tudor-knot PF11717.8 RJW67053.1 - 1.2e-06 28.3 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 RJW67053.1 - 0.5 10.1 1.3 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain RhoGEF PF00621.20 RJW67054.1 - 2.5e-25 89.8 0.1 4.5e-25 89.0 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 RJW67054.1 - 0.00031 20.6 0.0 0.00078 19.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_5 PF15405.6 RJW67054.1 - 0.0036 17.4 0.0 0.0085 16.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain E1_DerP2_DerF2 PF02221.15 RJW67055.1 - 3.3e-16 60.0 0.3 3.9e-16 59.7 0.3 1.0 1 0 0 1 1 1 1 ML domain Pyridoxal_deC PF00282.19 RJW67056.1 - 1.9e-132 441.5 0.0 3e-132 440.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 RJW67056.1 - 1.9e-05 24.1 0.0 2.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 RJW67056.1 - 0.015 14.0 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF4817 PF16087.5 RJW67057.1 - 0.0006 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_IclR PF09339.10 RJW67057.1 - 0.0028 17.4 0.5 0.011 15.5 0.1 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 RJW67057.1 - 0.096 12.6 0.4 4 7.4 0.0 2.5 2 0 0 2 2 2 0 MarR family Metallophos PF00149.28 RJW67058.1 - 2.7e-36 126.0 0.0 4.1e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RJW67058.1 - 1.5e-14 54.1 0.0 3.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Retinin_C PF04527.12 RJW67059.1 - 0.09 13.0 1.5 0.14 12.4 1.5 1.3 1 1 0 1 1 1 0 Drosophila Retinin like protein rve PF00665.26 RJW67060.1 - 9.9e-07 29.0 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain ig PF00047.25 RJW67061.1 - 0.062 13.5 0.1 0.086 13.0 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin domain PT PF04886.12 RJW67062.1 - 1.2e-08 34.3 20.3 0.067 12.8 0.0 5.2 2 2 0 2 2 2 2 PT repeat Amelotin PF15757.5 RJW67062.1 - 0.068 12.7 9.2 0.069 12.7 2.1 2.8 1 1 1 2 2 2 0 Amelotin zf-C2H2_4 PF13894.6 RJW67066.1 - 1.9e-18 65.6 49.0 0.0013 19.4 0.3 7.4 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW67066.1 - 2.3e-16 59.2 53.8 0.00037 20.8 0.4 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW67066.1 - 7.1e-09 35.7 32.9 0.028 14.7 0.5 7.3 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 RJW67066.1 - 2.7e-08 33.5 19.8 0.00099 18.9 0.1 6.9 7 0 0 7 7 7 2 zinc-finger of a C2HC-type zf-met PF12874.7 RJW67066.1 - 5e-08 33.1 28.5 0.13 12.7 0.0 7.3 7 1 1 8 8 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RJW67066.1 - 3e-06 27.1 41.9 0.44 10.6 0.2 7.3 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW67066.1 - 4.5e-06 26.9 46.7 0.0021 18.4 1.7 6.8 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_11 PF16622.5 RJW67066.1 - 1.2e-05 24.9 41.8 0.015 15.0 2.5 7.3 7 0 0 7 7 7 4 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 RJW67066.1 - 4.4e-05 23.1 8.4 0.088 12.6 0.0 4.8 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 RJW67066.1 - 5.3e-05 23.9 21.5 0.047 14.4 0.1 4.3 1 1 2 4 4 4 2 Zinc finger C2H2-type, 3 repeats C1_1 PF00130.22 RJW67066.1 - 0.0019 18.0 27.2 0.0023 17.8 3.3 4.6 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_9 PF16293.5 RJW67066.1 - 0.015 15.2 9.5 2.1 8.3 0.1 5.3 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 RJW67066.1 - 0.016 15.5 33.5 0.11 12.8 3.1 5.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf_PR_Knuckle PF18445.1 RJW67066.1 - 0.02 14.7 1.3 0.071 12.9 0.1 2.6 3 0 0 3 3 3 0 PR zinc knuckle motif Mut7-C PF01927.16 RJW67066.1 - 0.036 14.2 20.1 0.41 10.8 1.7 3.6 1 1 3 4 4 4 0 Mut7-C RNAse domain zinc_ribbon_15 PF17032.5 RJW67066.1 - 0.059 14.1 21.3 0.63 10.8 0.7 4.1 2 1 1 4 4 4 0 zinc-ribbon family Rad50_zn_hook PF04423.14 RJW67066.1 - 0.067 13.0 1.8 1.3 8.9 0.0 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf_C2H2_ZHX PF18387.1 RJW67066.1 - 0.58 9.8 0.1 0.58 9.8 0.1 4.6 3 1 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2256 PF10013.9 RJW67066.1 - 7.5 6.8 22.9 6.7 6.9 0.3 6.4 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) Striatin PF08232.12 RJW67069.1 - 2.5e-40 138.6 2.2 4.7e-40 137.7 2.2 1.5 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 RJW67069.1 - 2.2e-23 82.1 9.0 0.0016 19.2 0.0 7.9 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW67069.1 - 0.00018 21.7 0.0 4.2 7.7 0.0 4.4 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RJW67069.1 - 0.027 13.2 0.0 0.54 8.9 0.0 2.3 1 1 0 2 2 2 0 Nup133 N terminal like Med30 PF11315.8 RJW67069.1 - 0.1 12.8 0.3 0.18 12.0 0.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF4482 PF14818.6 RJW67069.1 - 0.68 10.8 3.0 1.7 9.5 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Toxin_3 PF00537.18 RJW67072.1 - 0.052 13.8 0.4 0.052 13.8 0.4 2.7 1 1 2 3 3 3 0 Scorpion toxin-like domain MAT1 PF06391.13 RJW67074.1 - 1.4e-37 129.5 18.6 1.4e-37 129.5 18.6 1.5 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 RJW67074.1 - 2.5e-10 40.1 5.7 4.7e-10 39.2 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW67074.1 - 0.00018 21.3 7.8 0.00075 19.3 7.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW67074.1 - 0.00024 21.1 6.3 0.00091 19.2 6.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RJW67074.1 - 0.00058 19.8 6.7 0.0011 18.9 6.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 RJW67074.1 - 0.012 15.4 2.6 0.3 10.9 0.6 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 RJW67074.1 - 0.034 14.0 5.5 0.094 12.6 5.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 RJW67074.1 - 0.077 12.7 6.7 0.28 10.9 6.4 2.0 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_2 PF13639.6 RJW67074.1 - 0.14 12.5 9.7 0.075 13.4 7.1 2.0 2 1 0 2 2 1 0 Ring finger domain zf-UDP PF14569.6 RJW67074.1 - 0.26 11.4 7.9 0.061 13.5 1.8 2.2 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 RJW67074.1 - 0.38 10.6 6.7 0.1 12.4 1.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TackOD1 PF18551.1 RJW67074.1 - 2.4 7.8 7.4 0.32 10.6 2.8 1.8 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 RJW67074.1 - 3.4 7.8 6.0 21 5.3 6.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 RJW67074.1 - 4.5 7.5 7.7 16 5.7 7.7 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING GSG-1 PF07803.11 RJW67077.1 - 0.59 10.1 4.4 1.4 8.9 0.3 2.5 2 1 0 3 3 3 0 GSG1-like protein DUF872 PF05915.12 RJW67077.1 - 2 8.6 8.8 0.5 10.6 1.1 2.4 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SLC12 PF03522.15 RJW67079.1 - 0.0054 15.8 2.5 0.0068 15.5 2.5 1.1 1 0 0 1 1 1 1 Solute carrier family 12 Zip PF02535.22 RJW67079.1 - 0.013 14.7 2.5 0.024 13.9 2.5 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 RJW67079.1 - 0.067 12.0 1.8 0.073 11.9 1.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FGF-BP1 PF06473.12 RJW67079.1 - 0.097 12.5 12.3 0.13 12.0 12.3 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) PPL5 PF18168.1 RJW67079.1 - 0.14 11.5 2.7 0.19 11.0 2.7 1.3 1 0 0 1 1 1 0 Prim-pol family 5 ETRAMP PF09716.10 RJW67079.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FAM176 PF14851.6 RJW67079.1 - 0.22 11.2 7.0 0.031 13.9 2.2 2.0 2 0 0 2 2 2 0 FAM176 family CPSF100_C PF13299.6 RJW67079.1 - 0.28 11.4 9.5 0.47 10.6 9.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pox_A14 PF05767.12 RJW67079.1 - 0.77 9.9 10.3 0.15 12.2 1.8 2.5 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 Ureide_permease PF07168.11 RJW67079.1 - 0.8 8.4 4.1 0.3 9.8 0.6 1.8 1 1 0 2 2 2 0 Ureide permease DUF913 PF06025.12 RJW67079.1 - 1.1 8.2 3.6 1.3 7.9 3.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EOS1 PF12326.8 RJW67079.1 - 1.2 9.0 5.2 1.9 8.4 5.2 1.6 1 1 0 1 1 1 0 N-glycosylation protein Claudin_2 PF13903.6 RJW67079.1 - 1.3 8.8 17.0 0.28 10.9 0.9 3.0 1 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Menin PF05053.13 RJW67079.1 - 1.5 7.1 6.3 1.8 6.8 6.3 1.1 1 0 0 1 1 1 0 Menin V_ATPase_I PF01496.19 RJW67079.1 - 1.6 6.5 6.2 2.1 6.1 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MpPF26 PF07666.11 RJW67079.1 - 2.3 8.3 7.5 0.19 11.9 1.7 2.0 2 0 0 2 2 2 0 M penetrans paralogue family 26 GAGA_bind PF06217.12 RJW67079.1 - 2.5 8.3 11.0 0.053 13.8 4.5 1.5 2 0 0 2 2 1 0 GAGA binding protein-like family Peptidase_S49_N PF08496.10 RJW67079.1 - 2.5 8.2 9.2 0.036 14.1 1.8 1.7 2 0 0 2 2 1 0 Peptidase family S49 N-terminal Pap_E4 PF02711.14 RJW67079.1 - 4.1 8.4 6.8 6.4 7.8 6.8 1.3 1 0 0 1 1 1 0 E4 protein Neur_chan_memb PF02932.16 RJW67079.1 - 5.1 7.1 6.3 0.45 10.5 0.9 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 RJW67079.1 - 5.3 6.8 15.0 8.6 6.1 15.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GOLD_2 PF13897.6 RJW67079.1 - 6.7 7.2 7.5 11 6.5 7.5 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Connexin PF00029.19 RJW67079.1 - 7.9 6.2 7.2 0.2 11.4 0.7 1.8 2 0 0 2 2 2 0 Connexin Claudin_3 PF06653.11 RJW67079.1 - 9.5 6.1 16.1 26 4.7 16.2 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like RNA_polI_A34 PF08208.11 RJW67079.1 - 9.9 6.2 27.1 13 5.8 27.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Fanconi_A_N PF15865.5 RJW67080.1 - 1.5e-13 50.9 0.0 2.5e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Fanconi anaemia group A protein N terminus Atrophin-1 PF03154.15 RJW67081.1 - 0.096 11.0 0.1 0.12 10.7 0.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family Cupin_4 PF08007.12 RJW67082.1 - 9.9e-58 196.1 1.9 1.7e-57 195.3 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 RJW67082.1 - 6.1e-10 39.2 0.3 1.6e-07 31.3 0.0 2.8 2 1 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.11 RJW67082.1 - 0.0068 16.1 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 RJW67082.1 - 0.008 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Cupin bZIP_2 PF07716.15 RJW67085.1 - 2.2e-11 43.7 10.6 3.1e-11 43.2 10.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RJW67085.1 - 0.0014 18.7 5.9 0.002 18.2 5.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor ETF PF01012.21 RJW67087.1 - 4.4e-43 147.3 1.1 5.9e-43 146.9 1.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain HARE-HTH PF05066.13 RJW67087.1 - 0.094 13.1 0.1 2.7 8.4 0.0 2.8 3 0 0 3 3 3 0 HB1, ASXL, restriction endonuclease HTH domain F5_F8_type_C PF00754.25 RJW67088.1 - 2e-11 44.1 0.0 3.1e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 F5/8 type C domain Patched PF02460.18 RJW67088.1 - 0.14 10.2 0.1 0.21 9.7 0.1 1.1 1 0 0 1 1 1 0 Patched family RVT_1 PF00078.27 RJW67089.1 - 2.3e-18 66.5 0.0 4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PMG PF05287.12 RJW67090.1 - 0.0075 16.3 64.3 1.2 9.2 9.7 4.2 1 1 2 3 3 3 2 PMG protein Peptidase_M6 PF05547.11 RJW67092.1 - 0.064 11.6 0.0 0.089 11.1 0.0 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 RVT_1 PF00078.27 RJW67093.1 - 2.8e-41 141.5 0.0 7.7e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW67093.1 - 5.7e-07 29.4 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase CRIM PF16978.5 RJW67095.1 - 6.2e-14 52.3 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 RJW67095.1 - 0.00024 21.4 0.0 0.029 14.6 0.0 2.5 2 0 0 2 2 2 2 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Met_10 PF02475.16 RJW67096.1 - 3.5e-51 173.8 0.0 5.2e-50 170.0 0.0 2.0 1 1 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 RJW67096.1 - 0.08 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DUF4548 PF15081.6 RJW67096.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) RVT_1 PF00078.27 RJW67097.1 - 5.1e-09 36.0 0.0 2.9e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TauE PF01925.19 RJW67100.1 - 0.0041 16.8 4.8 0.0058 16.3 4.8 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF2583 PF10762.9 RJW67100.1 - 0.085 13.3 0.9 0.11 12.9 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) DUF2070 PF09843.9 RJW67100.1 - 0.1 10.9 6.2 0.12 10.6 6.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF751 PF05421.11 RJW67100.1 - 0.15 12.8 0.5 0.15 12.8 0.5 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF751) SUR7 PF06687.12 RJW67100.1 - 0.33 10.6 10.4 0.053 13.1 6.2 1.6 1 1 0 1 1 1 0 SUR7/PalI family ECF_trnsprt PF12822.7 RJW67100.1 - 0.45 10.6 5.6 0.34 11.0 4.4 1.5 1 1 0 1 1 1 0 ECF transporter, substrate-specific component TssN PF17555.2 RJW67100.1 - 0.89 8.9 3.3 0.63 9.4 1.6 1.4 1 1 0 1 1 1 0 Type VI secretion system, TssN TruB_N PF01509.18 RJW67101.1 - 0.0019 18.6 0.0 0.1 12.9 0.0 2.3 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) N6-adenineMlase PF10237.9 RJW67101.1 - 0.043 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Asp_protease_2 PF13650.6 RJW67103.1 - 5.5e-06 26.9 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW67103.1 - 1.3e-05 25.6 0.0 2.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 RJW67103.1 - 0.053 13.8 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease UBX PF00789.20 RJW67104.1 - 2.1e-06 27.8 0.0 1e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 UBX domain Grg1 PF11034.8 RJW67104.1 - 0.1 12.8 0.5 0.28 11.4 0.5 1.7 1 0 0 1 1 1 0 Glucose-repressible protein Grg1 AAA_11 PF13086.6 RJW67104.1 - 0.24 11.2 5.9 0.47 10.2 5.9 1.4 1 0 0 1 1 1 0 AAA domain Dishevelled PF02377.15 RJW67107.1 - 2.5e-39 135.4 16.1 2.5e-39 135.4 16.1 1.8 2 1 0 2 2 2 1 Dishevelled specific domain DIX PF00778.17 RJW67107.1 - 1.3e-30 105.1 0.5 2.7e-30 104.0 0.3 1.7 2 0 0 2 2 2 1 DIX domain PDZ PF00595.24 RJW67107.1 - 8.5e-19 67.7 0.7 1.5e-18 66.9 0.7 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW67107.1 - 9.8e-07 28.5 0.1 2.1e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW67107.1 - 0.00057 20.1 0.2 0.0011 19.2 0.2 1.5 1 0 0 1 1 1 1 PDZ domain LRR19-TM PF15176.6 RJW67108.1 - 0.038 14.0 2.1 0.038 14.0 2.1 2.7 2 1 2 4 4 4 0 Leucine-rich repeat family 19 TM domain zf-HYPF PF07503.12 RJW67109.1 - 0.16 11.7 0.6 6.1 6.7 0.0 2.3 2 0 0 2 2 2 0 HypF finger Snf7 PF03357.21 RJW67110.1 - 1.1e-06 28.4 8.0 1.1e-06 28.4 8.0 1.6 1 1 1 2 2 2 1 Snf7 Biotin_lipoyl PF00364.22 RJW67113.1 - 4.3e-20 71.3 1.2 5.2e-20 71.1 1.2 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RJW67113.1 - 3.5e-13 49.2 0.6 1.2e-06 28.3 0.0 2.0 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 RJW67113.1 - 0.00016 22.3 0.0 0.46 11.2 0.0 2.1 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 RJW67113.1 - 0.0002 20.7 0.2 0.24 10.6 0.0 2.0 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion PYNP_C PF07831.13 RJW67113.1 - 0.00044 19.8 0.6 0.44 10.2 0.0 2.1 1 1 1 2 2 2 2 Pyrimidine nucleoside phosphorylase C-terminal domain RnfC_N PF13375.6 RJW67113.1 - 0.0018 18.2 1.1 0.0026 17.7 1.1 1.4 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 RJW67113.1 - 0.0038 16.7 0.4 0.0078 15.7 0.4 1.5 1 1 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PTS_EIIA_1 PF00358.20 RJW67113.1 - 0.0046 16.7 0.3 0.72 9.6 0.1 2.2 1 1 1 2 2 2 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 RJW67113.1 - 0.01 16.0 0.6 0.31 11.3 0.0 2.2 1 1 1 2 2 2 0 Peptidase family M23 GCV_H PF01597.19 RJW67113.1 - 0.015 15.2 0.2 0.017 15.0 0.2 1.1 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF2118 PF09891.9 RJW67113.1 - 0.072 13.0 0.5 0.99 9.4 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) PyrI PF01948.18 RJW67113.1 - 0.096 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain YqfD PF06898.11 RJW67113.1 - 0.14 10.9 3.8 0.9 8.3 0.7 2.1 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD RVT_1 PF00078.27 RJW67115.1 - 0.01 15.4 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RCR PF12273.8 RJW67116.1 - 0.00015 22.4 0.1 0.00063 20.4 0.1 2.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.6 RJW67116.1 - 0.12 12.6 0.0 0.12 12.6 0.0 6.8 5 3 2 8 8 8 0 Wnt and FGF inhibitory regulator Hum_adeno_E3A PF05393.11 RJW67116.1 - 0.16 12.0 0.2 0.77 9.8 0.2 2.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Histone PF00125.24 RJW67119.1 - 9.8e-13 48.6 0.0 1.3e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 RJW67119.1 - 2.5e-12 46.3 1.0 6.6e-12 45.0 1.0 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 RJW67119.1 - 1.5e-06 28.4 0.0 2.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Usp PF00582.26 RJW67120.1 - 8.5e-26 91.2 0.0 1.4e-25 90.5 0.0 1.3 1 1 0 1 1 1 1 Universal stress protein family SK_channel PF03530.14 RJW67121.1 - 4.3e-37 126.6 1.2 7.8e-37 125.8 1.2 1.4 1 0 0 1 1 1 1 Calcium-activated SK potassium channel G-alpha PF00503.20 RJW67124.1 - 4.7e-90 302.3 6.3 8.4e-57 192.9 0.9 2.3 2 1 1 3 3 3 2 G-protein alpha subunit Arf PF00025.21 RJW67124.1 - 8.4e-11 41.6 1.1 2.9e-07 30.1 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 RJW67124.1 - 0.052 13.8 0.1 5.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RJW67124.1 - 0.092 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 RJW67124.1 - 0.23 10.8 2.5 9.4 5.5 2.5 2.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region tRNA-synt_1c PF00749.21 RJW67127.1 - 1.5e-105 352.6 0.0 2.4e-105 351.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 RJW67127.1 - 2.2e-41 141.6 0.0 4.2e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 RJW67127.1 - 5.6e-09 36.8 0.0 1e-08 36.0 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF1652 PF07865.11 RJW67127.1 - 0.19 11.6 1.8 34 4.4 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) zf-C2H2 PF00096.26 RJW67128.1 - 5.4e-24 83.3 33.9 2.4e-06 27.7 0.5 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW67128.1 - 8.9e-20 69.7 32.0 0.00029 21.4 1.2 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW67128.1 - 3.9e-09 36.5 29.5 0.012 16.0 0.9 7.1 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW67128.1 - 6.4e-09 35.6 24.3 0.025 14.6 0.9 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 RJW67128.1 - 0.00011 22.5 26.9 0.14 12.6 0.7 6.2 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RJW67128.1 - 0.00021 21.5 18.1 0.013 15.8 3.5 3.5 2 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 RJW67128.1 - 0.002 17.8 28.8 0.11 12.3 0.3 5.3 5 1 0 5 5 5 3 C2H2-type zinc-finger domain zf-BED PF02892.15 RJW67128.1 - 0.0036 17.3 26.5 0.33 11.0 3.1 4.7 2 2 2 4 4 4 3 BED zinc finger zf-C2H2_3rep PF18868.1 RJW67128.1 - 0.0067 17.1 10.8 1 10.1 3.3 3.4 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats NupH_GANP PF16768.5 RJW67128.1 - 0.03 14.0 0.4 0.044 13.5 0.4 1.3 1 0 0 1 1 1 0 Nucleoporin homology of Germinal-centre associated nuclear protein zf-ISL3 PF14690.6 RJW67128.1 - 0.035 14.8 2.3 0.035 14.8 2.3 4.1 3 1 1 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_2 PF12756.7 RJW67128.1 - 0.036 14.4 23.0 1.3 9.3 1.3 4.7 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RJW67128.1 - 0.071 13.2 1.1 0.071 13.2 1.1 4.2 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 RJW67128.1 - 0.1 12.9 28.1 0.71 10.2 0.6 5.8 5 1 1 6 6 6 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 RJW67128.1 - 0.15 12.1 16.1 26 4.9 2.4 4.1 1 1 3 4 4 4 0 CpXC protein YhfH PF14149.6 RJW67128.1 - 0.31 11.0 11.7 2.4 8.2 0.3 3.5 2 1 1 3 3 3 0 YhfH-like protein zf_C2H2_ZHX PF18387.1 RJW67128.1 - 0.45 10.2 0.1 0.45 10.2 0.1 5.0 4 1 2 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 RJW67128.1 - 0.47 10.2 29.8 1.5 8.7 0.1 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type zf_UBZ PF18439.1 RJW67128.1 - 0.54 9.9 0.1 0.54 9.9 0.1 6.2 6 1 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 RJW67128.1 - 0.63 10.6 0.2 0.63 10.6 0.2 3.5 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain DUF2757 PF10955.8 RJW67128.1 - 3.2 8.1 0.0 3.2 8.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2757) zf-ribbon_3 PF13248.6 RJW67128.1 - 3.6 7.1 11.1 2 7.9 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RJW67128.1 - 5.8 7.7 18.1 0.68 10.7 1.1 3.6 1 1 3 4 4 4 0 zinc-ribbon family zf-C2H2_4 PF13894.6 RJW67129.1 - 1.9e-15 56.2 31.5 0.00075 20.1 1.3 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW67129.1 - 9.6e-13 47.8 36.2 0.00011 22.4 1.8 6.1 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW67129.1 - 2.2e-08 34.1 30.8 0.0087 16.4 2.3 6.7 6 1 0 6 6 6 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW67129.1 - 2.3e-07 30.6 7.8 5.6e-06 26.2 1.6 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW67129.1 - 4.4e-05 23.1 25.5 0.42 10.4 0.4 5.7 5 0 0 5 5 5 4 zinc-finger C2H2-type zf-Di19 PF05605.12 RJW67129.1 - 0.00029 21.1 4.2 0.00029 21.1 4.2 3.3 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 RJW67129.1 - 0.00067 20.0 18.8 0.091 13.1 0.4 4.2 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.7 RJW67129.1 - 0.02 15.0 3.2 3.9 7.7 0.1 3.7 3 0 0 3 3 3 0 Zinc-binding YhfH PF14149.6 RJW67129.1 - 0.059 13.3 3.2 32 4.6 0.1 3.6 3 0 0 3 3 3 0 YhfH-like protein zf-C2H2_3rep PF18868.1 RJW67129.1 - 0.062 14.0 13.8 0.78 10.4 1.3 3.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 RJW67129.1 - 0.099 12.8 12.5 0.35 11.0 0.3 4.0 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 RJW67129.1 - 0.11 12.8 10.4 0.85 10.0 1.6 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 RJW67129.1 - 0.12 12.9 0.7 0.12 12.9 0.7 4.8 5 0 0 5 5 4 0 Zinc-finger of C2H2 type ADK_lid PF05191.14 RJW67129.1 - 0.14 12.2 5.6 0.44 10.6 0.4 3.0 2 1 0 2 2 2 0 Adenylate kinase, active site lid ROS_MUCR PF05443.11 RJW67129.1 - 0.14 12.2 1.9 0.66 10.0 0.9 2.7 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein TF_Zn_Ribbon PF08271.12 RJW67129.1 - 0.42 10.2 8.4 9 5.9 1.6 3.5 3 1 0 3 3 3 0 TFIIB zinc-binding zf-H2C2_5 PF13909.6 RJW67129.1 - 1.1 9.1 17.2 3.4 7.5 1.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain TerY_C PF15616.6 RJW67129.1 - 1.2 9.3 8.2 0.8 9.8 0.3 2.6 1 1 0 2 2 2 0 TerY-C metal binding domain DpnI PF06044.12 RJW67129.1 - 2.1 8.0 5.6 0.27 10.8 1.2 1.7 2 0 0 2 2 2 0 Dam-replacing family zinc_ribbon_15 PF17032.5 RJW67129.1 - 3 8.6 13.8 2 9.2 0.9 3.0 1 1 1 3 3 3 0 zinc-ribbon family CpXC PF14353.6 RJW67129.1 - 3.7 7.6 13.1 4.6 7.3 3.9 3.7 1 1 2 3 3 3 0 CpXC protein zf_UBZ PF18439.1 RJW67129.1 - 4.6 6.9 15.8 5.2 6.8 0.4 4.6 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger RecR PF02132.15 RJW67129.1 - 5 6.8 8.7 21 4.8 0.2 3.6 4 0 0 4 4 4 0 RecR protein zinc-ribbons_6 PF07191.12 RJW67129.1 - 7.7 6.6 16.4 2.6 8.1 3.0 3.3 3 1 0 3 3 3 0 zinc-ribbons E1_DerP2_DerF2 PF02221.15 RJW67132.1 - 3.9e-09 37.0 0.3 3.9e-07 30.6 0.2 2.4 2 0 0 2 2 2 1 ML domain DUF1196 PF06709.11 RJW67132.1 - 0.055 13.6 1.5 0.9 9.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1196) Cu-oxidase_3 PF07732.15 RJW67132.1 - 0.09 12.8 0.1 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Multicopper oxidase STAT_int PF02865.17 RJW67133.1 - 0.01 16.3 0.3 0.017 15.6 0.3 1.3 1 0 0 1 1 1 0 STAT protein, protein interaction domain LMF1 PF06762.14 RJW67134.1 - 1.2e-75 255.3 19.2 1.6e-75 255.0 19.2 1.2 1 0 0 1 1 1 1 Lipase maturation factor MscL PF01741.18 RJW67134.1 - 2.1 8.6 4.7 5.9 7.2 3.6 2.1 1 1 1 2 2 2 0 Large-conductance mechanosensitive channel, MscL Anoctamin PF04547.12 RJW67135.1 - 2.3e-44 152.0 0.2 2.9e-44 151.7 0.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel ABC2_membrane_3 PF12698.7 RJW67135.1 - 0.026 13.7 0.1 0.036 13.2 0.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-CDGSH PF09360.10 RJW67138.1 - 2.9e-15 56.2 10.0 2.6e-09 37.1 0.2 3.6 3 0 0 3 3 3 3 Iron-binding zinc finger CDGSH type RVT_1 PF00078.27 RJW67139.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dpy-30 PF05186.13 RJW67140.1 - 5.8e-12 45.1 0.1 1.6e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 RJW67140.1 - 1.9e-09 37.8 1.1 0.0048 17.0 0.0 4.0 5 0 0 5 5 4 2 Adenylate kinase AAA_17 PF13207.6 RJW67140.1 - 2.6e-05 24.7 6.8 0.0011 19.4 0.0 4.0 3 1 1 4 4 4 1 AAA domain Hydin_ADK PF17213.3 RJW67140.1 - 0.00017 22.0 0.5 0.0026 18.1 0.0 2.3 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 RJW67140.1 - 0.00041 20.9 2.9 0.0025 18.4 0.0 3.8 5 1 0 5 5 5 1 AAA domain AAA_22 PF13401.6 RJW67140.1 - 0.003 17.8 0.2 0.55 10.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 RJW67140.1 - 0.0044 17.2 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 RJW67140.1 - 0.0049 16.8 2.3 1 9.2 0.0 3.1 3 0 0 3 3 3 1 Deoxynucleoside kinase AAA PF00004.29 RJW67140.1 - 0.0062 17.0 0.1 0.023 15.1 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RJW67140.1 - 0.0089 16.3 5.6 0.021 15.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain Epimerase PF01370.21 RJW67140.1 - 0.011 15.2 0.1 0.076 12.5 0.0 2.4 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family AAA_16 PF13191.6 RJW67140.1 - 0.028 14.8 0.9 0.066 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 RJW67140.1 - 0.05 13.7 0.0 1.8 8.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 RJW67140.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RJW67140.1 - 0.097 12.6 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 NTPase Endonuc_Holl PF10107.9 RJW67140.1 - 1.5 8.6 5.3 4.3 7.2 5.3 1.7 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3987 PF13148.6 RJW67140.1 - 4.3 6.2 12.7 0.13 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DSBA PF01323.20 RJW67142.1 - 7e-34 117.3 0.0 5.6e-32 111.1 0.0 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Calpain_inhib PF00748.19 RJW67143.1 - 1.1 9.7 11.6 0.47 11.0 0.4 2.2 2 0 0 2 2 2 0 Calpain inhibitor LIM PF00412.22 RJW67144.1 - 4.2e-54 180.6 53.8 8.4e-13 48.3 0.8 5.1 5 0 0 5 5 5 5 LIM domain TPR_1 PF00515.28 RJW67146.1 - 1.1e-06 28.2 5.2 0.011 15.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW67146.1 - 0.0005 20.0 12.2 0.033 14.3 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW67146.1 - 0.016 15.6 2.0 0.38 11.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 RJW67146.1 - 0.11 12.7 2.1 6.1 7.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RJW67146.1 - 0.48 10.8 6.6 0.3 11.4 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Profilin PF00235.19 RJW67147.1 - 9.5e-05 22.7 0.0 0.0001 22.6 0.0 1.1 1 0 0 1 1 1 1 Profilin PIH1 PF08190.12 RJW67149.1 - 2.3e-33 115.0 3.2 1.5e-30 105.8 2.5 3.1 2 1 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 RJW67149.1 - 1.3e-18 67.2 0.0 2.6e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain zf-H2C2_2 PF13465.6 RJW67151.1 - 1.3e-10 41.2 61.3 1.3e-06 28.6 5.4 8.6 9 0 0 9 9 9 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 RJW67151.1 - 2.3e-07 30.4 65.4 8.2e-05 22.3 1.0 6.4 6 0 0 6 6 6 5 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 RJW67151.1 - 5.2e-06 26.6 77.0 0.00072 19.9 3.9 8.7 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW67151.1 - 2.3 9.3 70.1 0.075 13.9 3.3 8.7 8 0 0 8 8 8 0 C2H2-type zinc finger rve PF00665.26 RJW67152.1 - 0.001 19.2 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RJW67152.1 - 0.068 13.0 0.1 0.12 12.1 0.1 1.5 1 1 0 1 1 1 0 Integrase core domain FXa_inhibition PF14670.6 RJW67153.1 - 5.1e-45 151.5 128.6 8.9e-11 41.9 6.3 27.4 12 3 9 22 22 22 9 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RJW67153.1 - 3.8e-29 100.2 44.8 1.6e-10 40.7 2.5 27.6 27 5 1 28 28 28 8 Complement Clr-like EGF-like Laminin_EGF PF00053.24 RJW67153.1 - 5.1e-22 77.8 395.8 8.6e-05 22.6 12.6 23.6 5 4 18 23 23 23 12 Laminin EGF domain EGF_CA PF07645.15 RJW67153.1 - 2.8e-17 62.6 54.3 6.3e-09 35.9 4.9 24.8 18 5 4 22 22 22 6 Calcium-binding EGF domain EGF PF00008.27 RJW67153.1 - 0.0011 19.2 9.0 0.0011 19.2 9.0 28.1 26 6 0 26 26 26 12 EGF-like domain EGF_2 PF07974.13 RJW67153.1 - 0.0022 18.3 12.7 0.0022 18.3 12.7 34.2 28 9 5 33 33 33 11 EGF-like domain RVT_1 PF00078.27 RJW67154.1 - 0.0007 19.2 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ion_trans_2 PF07885.16 RJW67155.1 - 4e-25 87.6 25.1 4.9e-14 52.1 1.2 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RJW67155.1 - 4.9e-06 26.0 7.0 0.0017 17.6 0.2 2.5 2 1 0 2 2 2 2 Ion transport protein RVT_1 PF00078.27 RJW67156.1 - 7e-07 29.0 0.0 2.9e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SPC25 PF06703.11 RJW67157.1 - 2e-45 154.5 0.0 2.3e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Claudin_2 PF13903.6 RJW67157.1 - 0.013 15.3 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Wzy_C PF04932.15 RJW67157.1 - 0.07 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase X PF00739.19 RJW67159.1 - 0.26 11.4 3.5 0.3 11.2 0.3 2.6 3 0 0 3 3 3 0 Trans-activation protein X SUI1 PF01253.22 RJW67160.1 - 6.7e-19 68.2 0.5 9.7e-19 67.7 0.5 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2012 PF09430.10 RJW67162.1 - 2.3e-22 79.4 0.0 3.2e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CcmH PF03918.14 RJW67162.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein NUDIX PF00293.28 RJW67164.1 - 3.1e-10 40.2 0.0 5.9e-10 39.3 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain DBC1 PF14443.6 RJW67164.1 - 0.13 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 DBC1 Ank_4 PF13637.6 RJW67166.1 - 4.1e-13 49.5 0.1 4.3e-07 30.4 0.0 2.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW67166.1 - 3.6e-12 46.7 0.2 7.4e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW67166.1 - 1.8e-08 34.5 0.1 2.2e-05 24.6 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW67166.1 - 3.5e-06 26.9 0.4 0.004 17.5 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 RJW67166.1 - 7.1e-06 26.2 0.3 0.0032 17.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat PHO4 PF01384.20 RJW67167.1 - 0.16 11.0 8.5 0.22 10.5 8.0 1.4 1 1 0 1 1 1 0 Phosphate transporter family SirB PF04247.12 RJW67167.1 - 0.39 10.8 8.6 0.59 10.2 8.6 1.4 1 1 0 1 1 1 0 Invasion gene expression up-regulator, SirB DUF1360 PF07098.11 RJW67167.1 - 1.1 9.2 6.1 0.25 11.3 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1360) RVT_1 PF00078.27 RJW67169.1 - 0.01 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) V-set PF07686.17 RJW67170.1 - 0.012 15.8 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin V-set domain Ig_3 PF13927.6 RJW67170.1 - 0.036 14.6 0.2 9 7.0 0.0 2.9 2 1 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 RJW67170.1 - 0.09 13.0 0.1 5.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain Ig_6 PF18452.1 RJW67170.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain Aldedh PF00171.22 RJW67173.1 - 1.4e-140 468.9 0.0 1.7e-140 468.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 RJW67173.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RRF PF01765.19 RJW67173.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Ig_3 PF13927.6 RJW67174.1 - 3.2e-35 120.6 0.2 2.3e-09 37.7 0.1 5.9 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 RJW67174.1 - 4.7e-24 84.3 0.0 4.3e-09 36.3 0.0 6.5 5 2 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW67174.1 - 1e-20 73.8 1.4 5.1e-05 23.5 0.0 6.4 7 0 0 7 7 7 5 Immunoglobulin domain Ldl_recept_a PF00057.18 RJW67174.1 - 2.2e-16 59.7 40.1 4e-07 30.1 8.7 4.0 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A ig PF00047.25 RJW67174.1 - 4.2e-14 52.5 0.5 0.014 15.5 0.0 6.5 5 3 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 RJW67174.1 - 3.7e-13 49.6 1.2 0.087 13.0 0.0 7.8 6 3 1 7 7 7 4 Immunoglobulin V-set domain C2-set PF05790.15 RJW67174.1 - 0.011 15.9 0.0 0.62 10.3 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain PKD_3 PF16820.5 RJW67174.1 - 0.078 12.7 0.1 0.58 10.0 0.0 2.5 3 0 0 3 3 3 0 PKD-like domain Innexin PF00876.18 RJW67175.1 - 1.2e-210 699.0 29.0 3.7e-108 361.9 13.1 2.0 2 0 0 2 2 2 2 Innexin MFS_1 PF07690.16 RJW67177.1 - 4.3e-23 81.8 63.6 9.4e-22 77.4 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YBD PF17725.1 RJW67179.1 - 8.8e-75 251.1 0.0 1.3e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 RJW67179.1 - 4.6e-25 87.5 0.1 1e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 TEA/ATTS domain DUF5524 PF17662.1 RJW67180.1 - 2.4e-13 50.1 2.0 9e-12 44.9 0.0 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5524) MFS_1 PF07690.16 RJW67182.1 - 2.3e-27 95.8 24.9 2.3e-27 95.8 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RJW67182.1 - 0.0029 16.2 7.1 0.0029 16.2 7.1 3.2 3 0 0 3 3 3 1 MFS/sugar transport protein RRM_1 PF00076.22 RJW67183.1 - 1e-10 41.3 0.0 0.00027 20.7 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SWIRM PF04433.17 RJW67185.1 - 0.00041 20.6 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain zf-CW PF07496.15 RJW67185.1 - 0.0072 16.3 6.8 0.0072 16.3 6.8 2.3 2 0 0 2 2 2 1 CW-type Zinc Finger DUF484 PF04340.12 RJW67185.1 - 0.16 11.7 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF484 MFS_1 PF07690.16 RJW67187.1 - 2.5e-23 82.6 37.6 5.9e-23 81.3 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 RJW67191.1 - 1.3e-07 32.2 3.6 0.0073 17.1 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40_like PF17005.5 RJW67191.1 - 0.0024 17.3 0.1 1.3 8.3 0.0 2.4 1 1 1 2 2 2 2 WD40-like domain Gar1 PF04410.14 RJW67193.1 - 4e-29 101.4 0.0 2.4e-15 56.6 0.0 2.3 2 0 0 2 2 2 2 Gar1/Naf1 RNA binding region PTS_EIIB PF00367.20 RJW67193.1 - 0.12 11.9 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB YjcZ PF13990.6 RJW67194.1 - 0.0079 15.6 1.6 0.011 15.2 1.6 1.2 1 0 0 1 1 1 1 YjcZ-like protein C1_1 PF00130.22 RJW67195.1 - 1.4e-16 60.1 5.8 1.8e-16 59.8 5.8 1.1 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 RJW67195.1 - 0.017 14.7 2.3 0.017 14.7 2.3 1.9 2 0 0 2 2 2 0 PHD-finger PHD PF00628.29 RJW67195.1 - 0.091 12.7 5.2 0.2 11.5 5.2 1.6 1 1 0 1 1 1 0 PHD-finger Dcc1 PF09724.9 RJW67198.1 - 2.1e-58 198.2 0.2 2.8e-58 197.8 0.2 1.2 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Glyco_hydro_3 PF00933.21 RJW67198.1 - 2.8e-37 128.8 0.0 7.2e-37 127.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 RJW67198.1 - 2.2e-24 86.5 0.0 6.6e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 RJW67198.1 - 3e-10 40.0 0.0 1.1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain NIR_SIR PF01077.22 RJW67198.1 - 0.098 12.2 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain zf-C4 PF00105.18 RJW67200.1 - 2e-20 73.0 10.6 2e-20 73.0 10.6 2.2 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) RUN PF02759.19 RJW67201.1 - 6.6e-15 55.3 2.0 6.1e-10 39.2 0.0 3.2 3 1 0 3 3 3 2 RUN domain FYVE PF01363.21 RJW67201.1 - 0.015 15.4 1.6 0.041 14.0 1.6 1.8 1 0 0 1 1 1 0 FYVE zinc finger DUF641 PF04859.12 RJW67201.1 - 0.11 12.8 21.3 0.1 12.9 0.4 4.2 1 1 4 5 5 5 0 Plant protein of unknown function (DUF641) FPP PF05911.11 RJW67201.1 - 0.25 9.5 28.0 0.033 12.4 11.4 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Filament PF00038.21 RJW67201.1 - 0.29 10.7 27.6 0.21 11.2 9.6 3.4 2 1 1 3 3 3 0 Intermediate filament protein NPV_P10 PF05531.12 RJW67201.1 - 0.87 10.1 13.3 0.27 11.7 0.5 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 RJW67201.1 - 1.4 8.4 37.8 0.38 10.3 12.6 3.6 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain PRKG1_interact PF15898.5 RJW67201.1 - 1.4 9.9 34.4 0.44 11.5 1.5 4.0 3 1 1 4 4 3 0 cGMP-dependent protein kinase interacting domain AAA_13 PF13166.6 RJW67201.1 - 2.9 6.4 13.2 6 5.4 12.5 1.9 1 1 0 1 1 1 0 AAA domain USP8_interact PF08941.10 RJW67201.1 - 6.8 6.5 18.9 0.57 10.0 1.6 3.8 3 1 0 3 3 3 0 USP8 interacting Tup_N PF08581.10 RJW67201.1 - 7.5 6.9 17.3 0.094 13.0 0.8 4.8 4 1 2 6 6 6 0 Tup N-terminal DUF4407 PF14362.6 RJW67201.1 - 9.9 5.4 16.3 1.2e+02 1.9 15.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3509 PF12021.8 RJW67202.1 - 0.0039 16.9 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) MFS_1 PF07690.16 RJW67203.1 - 2.4e-16 59.6 28.8 2.4e-16 59.6 28.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 RJW67205.1 - 2.2e-66 224.0 0.0 3.3e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67205.1 - 2.6e-39 135.0 0.0 3.7e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 RJW67205.1 - 1.4e-24 86.3 0.0 2.9e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 RJW67205.1 - 4.4e-08 33.7 0.4 1e-07 32.6 0.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 RJW67205.1 - 0.00079 18.5 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RJW67205.1 - 0.0059 16.0 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RJW67205.1 - 0.061 12.7 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW67205.1 - 0.064 13.2 0.2 0.18 11.7 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 RJW67205.1 - 0.1 12.2 0.4 0.26 10.9 0.1 1.7 2 0 0 2 2 2 0 RIO1 family MFS_1 PF07690.16 RJW67206.1 - 4.5e-11 42.3 27.3 2.7e-09 36.4 6.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 RJW67207.1 - 2.8e-09 36.6 0.0 5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RJW67207.1 - 0.0021 18.1 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 RJW67207.1 - 0.0025 17.6 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 RJW67207.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter ADK PF00406.22 RJW67208.1 - 2.6e-43 147.7 0.0 3e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RJW67208.1 - 8.1e-21 74.9 0.0 1.3e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 RJW67208.1 - 7e-17 61.1 0.0 1.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 RJW67208.1 - 1e-06 29.3 0.0 1.8e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 RJW67208.1 - 0.00055 19.7 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 RJW67208.1 - 0.016 15.4 0.0 0.024 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Mucin_bdg PF03272.13 RJW67209.1 - 0.026 14.6 0.0 7.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module Waikav_capsid_1 PF12264.8 RJW67209.1 - 0.11 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Waikavirus capsid protein 1 MOZ_SAS PF01853.18 RJW67210.1 - 3.5e-69 232.1 0.1 4.8e-69 231.6 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RJW67210.1 - 3.7e-15 55.3 0.9 3.7e-15 55.3 0.9 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain zf-C2HC PF01530.18 RJW67210.1 - 5e-09 36.2 4.8 1.3e-08 34.8 4.8 1.8 1 0 0 1 1 1 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.7 RJW67210.1 - 0.0063 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1279 PF06916.13 RJW67210.1 - 0.043 14.3 1.6 3.8 8.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1279) Acetyltransf_1 PF00583.25 RJW67210.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FtsJ PF01728.19 RJW67211.1 - 1.2e-65 220.9 0.0 2.3e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PIG-S PF10510.9 RJW67211.1 - 5.6e-55 187.1 1.8 8.3e-55 186.6 1.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Tubulin_C PF03953.17 RJW67212.1 - 2.6e-27 95.5 0.0 4.1e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 RJW67212.1 - 6.1e-05 23.3 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF4949 PF16307.5 RJW67212.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) CBM_19 PF03427.13 RJW67213.1 - 0.5 10.4 4.7 0.13 12.3 1.0 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) MBOAT PF03062.19 RJW67214.1 - 4.1e-29 102.0 27.3 1.6e-28 100.1 27.1 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 RJW67214.1 - 0.0014 18.8 4.6 0.0049 17.1 4.6 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Prenyltransf PF01255.19 RJW67215.1 - 2.6e-37 128.5 0.0 3.7e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase LSM14 PF12701.7 RJW67216.1 - 3.9e-18 65.3 0.0 6.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 RJW67216.1 - 0.00036 20.6 0.0 0.00066 19.8 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 RJW67216.1 - 0.0027 18.6 0.1 0.01 16.7 0.1 2.0 1 1 0 1 1 1 1 FDF domain CTD_bind PF04818.13 RJW67219.1 - 3.3e-12 47.0 0.2 1.3e-11 45.2 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Ig_3 PF13927.6 RJW67220.1 - 2.1e-10 41.0 0.0 0.3 11.7 0.0 5.2 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 RJW67220.1 - 3.6e-06 27.2 0.0 3.5 8.0 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain Izumo-Ig PF16706.5 RJW67220.1 - 0.00071 19.6 0.1 0.73 9.9 0.0 3.8 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain V-set PF07686.17 RJW67220.1 - 0.0029 17.8 0.0 2.5 8.3 0.0 4.3 3 0 0 3 3 3 1 Immunoglobulin V-set domain RVT_1 PF00078.27 RJW67221.1 - 9.7e-15 54.7 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L10 PF00466.20 RJW67222.1 - 4.7e-21 74.8 0.2 9.2e-21 73.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 RJW67222.1 - 1.7e-19 69.6 0.2 3.2e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 RJW67222.1 - 7.4e-13 48.9 2.6 1.7e-12 47.8 2.6 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein RVT_1 PF00078.27 RJW67224.1 - 1.1e-44 152.6 0.0 2e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 RJW67224.1 - 0.0055 17.5 0.0 5.8 8.0 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat RabGAP-TBC PF00566.18 RJW67227.1 - 3.4e-28 98.8 0.0 5.1e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 RJW67227.1 - 1.3e-14 54.2 0.0 2.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67227.1 - 4.3e-08 32.8 0.0 1.3e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 RJW67227.1 - 0.0014 19.1 0.0 0.0073 16.8 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Mito_carr PF00153.27 RJW67233.1 - 1.5e-50 169.1 0.3 2.8e-19 68.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Asp PF00026.23 RJW67234.1 - 5.5e-58 196.9 0.0 6.5e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW67234.1 - 1.2e-11 45.2 0.0 2.6e-07 31.1 0.0 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RJW67234.1 - 0.0017 19.0 0.0 0.32 11.6 0.0 2.6 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW67234.1 - 0.15 12.7 0.1 55 4.4 0.0 3.3 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease WD40 PF00400.32 RJW67235.1 - 7.9e-38 127.8 16.4 2.3e-09 37.7 0.1 7.9 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW67235.1 - 2.3e-08 34.2 0.9 0.29 11.5 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RJW67235.1 - 2.2e-06 26.7 1.6 0.22 10.2 0.0 4.4 2 1 0 4 4 4 3 Nup133 N terminal like Nup160 PF11715.8 RJW67235.1 - 3.1e-06 26.2 2.3 0.022 13.4 0.1 4.6 1 1 1 5 5 5 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 RJW67235.1 - 5.5e-05 23.5 1.5 1 10.0 0.1 4.4 4 0 0 4 4 4 2 PQQ-like domain PQQ_2 PF13360.6 RJW67235.1 - 0.0003 20.5 0.2 0.12 12.0 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 RJW67235.1 - 0.0025 16.8 1.2 7 5.5 0.0 3.4 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 RJW67235.1 - 0.027 14.4 0.8 0.47 10.5 0.1 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat BBS2_Mid PF14783.6 RJW67235.1 - 0.035 14.1 0.1 3.2 7.8 0.0 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF5046 PF16465.5 RJW67235.1 - 0.051 13.0 0.1 0.2 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) RFX_DNA_binding PF02257.15 RJW67237.1 - 2.6e-23 82.4 0.1 4.3e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 RJW67237.1 - 0.02 15.4 0.0 0.033 14.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus D5 protein-like RFX5_N PF18326.1 RJW67237.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 RFX5 N-terminal domain Cdc6_C PF09079.11 RJW67237.1 - 0.086 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain NIF PF03031.18 RJW67238.1 - 9.9e-15 54.6 0.0 1.6e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UMPH-1 PF05822.12 RJW67239.1 - 2e-57 194.5 0.0 2.5e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 RJW67239.1 - 3.3e-05 24.4 0.0 4.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HA2 PF04408.23 RJW67240.1 - 2.7e-13 50.2 0.0 8.5e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RJW67240.1 - 2e-09 37.7 0.0 7.7e-09 35.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RJW67240.1 - 3.7e-05 23.6 0.0 9.9e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 RJW67240.1 - 0.0025 18.1 0.1 0.0078 16.6 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Cpn60_TCP1 PF00118.24 RJW67243.1 - 5e-143 477.3 10.0 6.5e-143 476.9 10.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3395 PF11875.8 RJW67243.1 - 1.6e-37 128.8 0.0 2.9e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 RJW67243.1 - 1.2e-16 60.6 0.0 4.1e-16 58.9 0.0 1.9 1 1 0 1 1 1 1 DnaJ domain EF-hand_1 PF00036.32 RJW67244.1 - 1.4e-08 33.7 0.6 2.2e-08 33.1 0.6 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 RJW67244.1 - 9.2e-07 28.1 0.4 1.4e-06 27.5 0.4 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 RJW67244.1 - 2.1e-06 28.1 0.1 2.5e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW67244.1 - 3.7e-05 23.5 1.2 5.1e-05 23.0 1.2 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW67244.1 - 0.00015 21.4 0.2 0.00027 20.6 0.1 1.5 1 1 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 RJW67244.1 - 0.0009 19.2 0.3 0.0009 19.2 0.3 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Amidase PF01425.21 RJW67245.1 - 2.9e-22 79.2 0.0 4.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Amidase PRKG1_interact PF15898.5 RJW67245.1 - 0.037 14.9 0.7 0.098 13.6 0.7 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 RJW67245.1 - 0.074 12.8 0.3 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4917 PF16263.5 RJW67245.1 - 0.084 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) Ion_trans PF00520.31 RJW67246.1 - 7.9e-27 94.0 12.5 2.9e-20 72.5 1.4 2.1 2 0 0 2 2 2 2 Ion transport protein Herpes_UL43 PF05072.13 RJW67246.1 - 0.0047 16.1 2.7 0.0059 15.7 2.7 1.1 1 0 0 1 1 1 1 Herpesvirus UL43 protein CrgA PF06781.12 RJW67246.1 - 0.3 11.2 1.9 0.39 10.8 0.1 2.0 2 0 0 2 2 2 0 Cell division protein CrgA PKD_channel PF08016.12 RJW67246.1 - 2.3 6.8 11.6 0.041 12.6 2.3 2.0 1 1 0 2 2 2 0 Polycystin cation channel DUF996 PF06195.13 RJW67246.1 - 6.4 7.1 15.6 52 4.1 15.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF996) eIF-5_eIF-2B PF01873.17 RJW67248.1 - 8.4e-34 115.9 0.3 1.7e-33 115.0 0.3 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 RJW67248.1 - 2.7e-20 72.3 0.7 6.5e-20 71.1 0.7 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon SpoIIIAH PF12685.7 RJW67248.1 - 0.82 9.5 6.9 0.33 10.8 1.9 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Pkinase PF00069.25 RJW67249.1 - 9.8e-63 212.0 0.0 1.3e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67249.1 - 4.4e-37 127.8 0.0 6.4e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 RJW67249.1 - 7.7e-27 92.9 20.2 5.1e-14 51.9 6.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 RJW67249.1 - 2.1e-13 50.4 0.0 3.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 RJW67249.1 - 1.8e-07 31.8 1.4 6.4e-07 30.0 1.4 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 RJW67249.1 - 2e-05 24.1 0.0 0.00054 19.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like C1_2 PF03107.16 RJW67249.1 - 0.0022 18.3 13.6 0.12 12.7 1.5 2.8 2 0 0 2 2 2 2 C1 domain Haspin_kinase PF12330.8 RJW67249.1 - 0.0027 16.7 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RJW67249.1 - 0.0071 15.7 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW67249.1 - 0.053 13.4 0.6 0.18 11.7 0.5 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family HSNSD PF12062.8 RJW67249.1 - 0.087 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase zf-RING_9 PF13901.6 RJW67249.1 - 0.3 11.0 16.1 2 8.3 2.3 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 RJW67249.1 - 0.34 10.5 13.6 2.8 7.6 0.9 3.1 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 RJW67249.1 - 0.43 10.7 14.4 0.32 11.1 4.9 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 RJW67249.1 - 6.9 6.8 8.9 11 6.1 0.6 2.6 2 0 0 2 2 2 0 PHD-finger DUF89 PF01937.19 RJW67250.1 - 3.7e-78 263.0 0.0 3.2e-76 256.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF89 Peptidase_A17 PF05380.13 RJW67251.1 - 6.6e-14 52.2 0.1 1.1e-13 51.5 0.1 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase Asp_protease_2 PF13650.6 RJW67251.1 - 0.00098 19.7 0.2 0.0019 18.8 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW67251.1 - 0.077 13.6 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease LsmAD PF06741.13 RJW67253.1 - 1.3e-12 48.1 0.0 3.1e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 LsmAD domain PAM2 PF07145.15 RJW67253.1 - 0.035 13.8 0.8 0.1 12.3 0.1 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region RIIa PF02197.17 RJW67253.1 - 0.23 11.2 1.5 0.71 9.6 1.5 1.8 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Amidase PF01425.21 RJW67254.1 - 9e-101 338.0 0.0 1.1e-100 337.7 0.0 1.1 1 0 0 1 1 1 1 Amidase GCP_N_terminal PF17681.1 RJW67255.1 - 4.2e-76 256.5 0.0 8.7e-76 255.5 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 RJW67255.1 - 1.4e-75 254.7 7.6 3e-75 253.6 7.6 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal CobT PF06213.12 RJW67256.1 - 0.12 11.8 21.1 0.16 11.3 21.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIIAH PF12685.7 RJW67256.1 - 0.88 9.4 8.5 1.4 8.7 8.5 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 RJW67256.1 - 4.3 5.4 35.5 5.3 5.1 35.5 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 RJW67256.1 - 9.2 4.9 9.1 11 4.7 9.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Terminase_4 PF05119.12 RJW67258.1 - 0.013 15.9 0.0 0.014 15.8 0.0 1.1 1 0 0 1 1 1 0 Phage terminase, small subunit TPR_2 PF07719.17 RJW67259.1 - 2.6e-11 42.7 3.2 0.0017 18.3 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW67259.1 - 3.2e-09 37.2 0.0 6.3e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW67259.1 - 9.5e-09 34.8 2.6 0.00041 20.3 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RJW67259.1 - 5e-07 29.3 6.2 0.021 14.7 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW67259.1 - 3.2e-06 27.5 0.6 0.23 12.4 0.1 4.8 2 1 3 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RJW67259.1 - 8e-06 26.2 0.1 0.49 11.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW67259.1 - 3.4e-05 24.4 0.9 0.39 11.4 0.0 3.8 2 2 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW67259.1 - 5e-05 23.0 0.4 0.25 11.5 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW67259.1 - 0.00018 21.7 0.8 0.0028 17.9 0.3 2.8 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RJW67259.1 - 0.0011 19.2 3.7 0.34 11.2 0.1 3.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW67259.1 - 0.0012 18.2 0.0 0.0038 16.6 0.0 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 RJW67259.1 - 0.0039 17.5 2.8 0.5 10.9 0.0 3.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW67259.1 - 0.091 12.9 0.0 5.8 7.2 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RJW67259.1 - 0.15 12.0 0.3 3.1 7.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 RJW67259.1 - 0.8 10.5 4.1 1.6 9.6 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat YabA PF06156.13 RJW67260.1 - 0.42 11.3 13.8 3.4 8.4 1.2 2.4 2 1 0 2 2 2 0 Initiation control protein YabA Med9 PF07544.13 RJW67260.1 - 0.5 10.5 11.5 0.087 12.9 4.2 2.5 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MCU PF04678.13 RJW67260.1 - 1 9.4 8.9 22 5.1 8.9 2.0 1 1 0 1 1 1 0 Mitochondrial calcium uniporter SlyX PF04102.12 RJW67260.1 - 2.9 8.6 11.2 8.3 7.1 4.3 3.2 2 1 0 2 2 2 0 SlyX AAA_11 PF13086.6 RJW67260.1 - 3.3 7.4 9.6 6 6.6 9.6 1.4 1 1 0 1 1 1 0 AAA domain kleA_kleC PF17383.2 RJW67260.1 - 3.4 8.1 8.1 0.56 10.6 0.5 2.9 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A DLP_helical PF18709.1 RJW67260.1 - 5.3 6.1 12.1 2.5 7.2 3.9 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain Lge1 PF11488.8 RJW67260.1 - 6 7.1 15.2 0.14 12.4 3.8 2.4 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 zf-HIT PF04438.16 RJW67261.1 - 1.2e-05 25.1 16.0 1.2e-05 25.1 16.0 1.9 2 0 0 2 2 2 1 HIT zinc finger PolC_DP2 PF03833.13 RJW67261.1 - 1 7.1 5.0 1.4 6.7 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ion_trans PF00520.31 RJW67262.1 - 5e-170 563.0 67.4 2.6e-60 203.7 19.0 3.1 3 0 0 3 3 3 3 Ion transport protein GPHH PF16905.5 RJW67262.1 - 7.8e-31 105.6 0.1 2.8e-29 100.6 0.2 2.4 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 RJW67262.1 - 2.4e-29 101.4 0.0 5.1e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.12 RJW67262.1 - 1.6e-11 43.6 59.0 2.7e-05 23.0 9.1 6.9 4 3 3 7 7 7 6 Polycystin cation channel Amidase PF01425.21 RJW67265.1 - 1.9e-104 350.2 0.0 2.3e-104 349.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Rhabdo_ncap PF00945.18 RJW67266.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein SelP_N PF04592.14 RJW67268.1 - 0.11 11.9 6.7 0.18 11.2 6.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Clathrin_bdg PF15045.6 RJW67269.1 - 0.0002 21.3 0.0 0.00065 19.6 0.0 2.0 1 1 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking FtsH_ext PF06480.15 RJW67269.1 - 0.11 12.8 1.8 0.25 11.7 1.8 1.6 1 0 0 1 1 1 0 FtsH Extracellular Kinesin PF00225.23 RJW67270.1 - 9.7e-33 113.5 0.0 7.9e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 RJW67270.1 - 4.2e-07 30.0 0.0 8.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Viral_Beta_CD PF04530.12 RJW67270.1 - 0.58 10.5 2.8 2.3 8.5 2.8 2.1 1 0 0 1 1 1 0 Viral Beta C/D like family Mito_carr PF00153.27 RJW67271.1 - 1.3e-49 166.1 2.1 1.1e-16 60.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Bacteriocin_IIc PF10439.9 RJW67271.1 - 0.99 9.6 6.9 9.2 6.5 0.0 3.2 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Kinesin PF00225.23 RJW67272.1 - 3.6e-91 305.6 0.3 5.4e-91 305.0 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RJW67272.1 - 2.1e-14 53.7 0.2 5.3e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Type2_restr_D3 PF16902.5 RJW67272.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Type-2 restriction enzyme D3 domain DUF4774 PF15999.5 RJW67272.1 - 0.041 13.7 0.8 0.12 12.2 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) ATPase_2 PF01637.18 RJW67272.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CREPT PF16566.5 RJW67272.1 - 0.32 11.1 7.7 3.2 7.9 0.2 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 RJW67272.1 - 2.4 8.4 5.2 0.51 10.5 1.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 RJW67272.1 - 3.9 7.5 8.5 1.2 9.3 1.0 2.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein OCRE PF17780.1 RJW67273.1 - 1.8e-13 50.3 12.7 2.9e-13 49.6 12.7 1.4 1 0 0 1 1 1 1 OCRE domain AhpC-TSA PF00578.21 RJW67273.1 - 0.0016 18.4 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family DUF347 PF03988.12 RJW67274.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Prenyltrans PF00432.21 RJW67275.1 - 9.3e-37 124.5 22.8 5.3e-11 42.1 1.7 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 RJW67275.1 - 0.0018 17.5 0.0 0.23 10.5 0.0 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 RJW67275.1 - 0.12 11.4 0.0 0.53 9.3 0.0 2.0 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain Innexin PF00876.18 RJW67276.1 - 3.5e-112 375.2 1.3 4.2e-112 374.9 1.3 1.0 1 0 0 1 1 1 1 Innexin Sld5 PF05916.11 RJW67278.1 - 2.6e-17 63.2 0.0 4.5e-17 62.5 0.0 1.3 1 1 0 1 1 1 1 GINS complex protein PCI PF01399.27 RJW67279.1 - 9e-19 67.9 0.5 4.2e-18 65.8 0.0 2.4 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 RJW67279.1 - 9.3e-13 48.0 1.3 2e-12 47.0 1.3 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Retrotrans_gag PF03732.17 RJW67279.1 - 0.32 11.3 5.2 12 6.2 0.1 3.5 2 1 1 3 3 3 0 Retrotransposon gag protein Takusan PF04822.13 RJW67279.1 - 1.5 8.7 12.0 0.99 9.3 0.3 3.6 4 0 0 4 4 4 0 Takusan Myb_DNA-binding PF00249.31 RJW67280.1 - 1.1e-08 35.1 0.0 0.011 16.0 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.24 RJW67280.1 - 1e-06 29.4 0.0 1.3e-05 25.8 0.0 2.8 3 0 0 3 3 3 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 RJW67280.1 - 7e-06 25.8 0.0 0.00044 20.1 0.2 2.5 2 0 0 2 2 2 1 Myb DNA-binding like Ntox28 PF15605.6 RJW67280.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 28 Pkinase_Tyr PF07714.17 RJW67282.1 - 2.5e-73 246.6 0.0 3.7e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW67282.1 - 1.4e-30 106.6 0.0 2.1e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 RJW67282.1 - 6e-17 61.5 0.0 1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW67282.1 - 7.6e-12 45.7 0.0 2.1e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RJW67282.1 - 4.4e-08 33.2 0.0 9.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RJW67282.1 - 3.4e-05 24.1 0.0 0.0001 22.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Fz PF01392.22 RJW67282.1 - 0.00021 21.9 6.2 0.00047 20.7 3.5 2.8 2 1 0 2 2 2 1 Fz domain V-set PF07686.17 RJW67282.1 - 0.001 19.2 0.0 0.0057 16.8 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 RJW67282.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain PRIMA1 PF16101.5 RJW67282.1 - 2.9 7.9 8.1 7.7 6.6 8.1 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Carb_bind PF10645.9 RJW67282.1 - 5.1 7.4 6.7 0.84 9.9 1.5 2.5 2 0 0 2 2 2 0 Carbohydrate binding Nuc_sug_transp PF04142.15 RJW67283.1 - 1.7e-106 356.0 15.6 1.9e-106 355.8 15.6 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RJW67283.1 - 0.0044 17.2 8.4 0.0044 17.2 8.4 2.6 2 2 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 RJW67283.1 - 0.37 10.0 17.2 0.56 9.4 17.2 1.3 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Helicase_C PF00271.31 RJW67284.1 - 8.3e-25 87.3 0.0 2.4e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RJW67284.1 - 9.5e-15 54.8 0.1 2.6e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4407 PF14362.6 RJW67284.1 - 0.021 14.2 1.5 0.03 13.7 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1840 PF08895.11 RJW67284.1 - 0.11 12.8 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) AMP-binding PF00501.28 RJW67285.1 - 6.1e-24 84.4 0.0 9.2e-23 80.5 0.0 2.4 2 1 0 2 2 2 1 AMP-binding enzyme PQQ_2 PF13360.6 RJW67285.1 - 3e-11 43.4 0.0 0.0012 18.5 0.0 3.6 1 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 RJW67285.1 - 1.2e-06 28.2 0.0 0.003 17.4 0.0 3.9 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 RJW67285.1 - 2.6e-06 27.7 0.4 0.1 13.1 0.0 6.2 7 0 0 7 7 7 1 PQQ-like domain PP-binding PF00550.25 RJW67285.1 - 0.019 15.3 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site Dynamin_N PF00350.23 RJW67286.1 - 0.026 14.6 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 RJW67286.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 RJW67286.1 - 0.076 13.5 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter fn3 PF00041.21 RJW67287.1 - 0 1165.8 113.3 1.6e-16 60.4 0.0 49.2 50 0 0 50 50 50 41 Fibronectin type III domain I-set PF07679.16 RJW67287.1 - 7.1e-284 917.0 0.0 1.1e-17 63.8 0.0 30.8 29 1 0 29 29 29 26 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW67287.1 - 7.7e-190 616.0 0.0 7.9e-12 45.6 0.0 28.6 28 0 0 28 28 27 24 Immunoglobulin domain ig PF00047.25 RJW67287.1 - 1.6e-85 281.4 0.0 1.5e-09 37.9 0.1 26.6 28 0 0 28 28 28 12 Immunoglobulin domain Ig_2 PF13895.6 RJW67287.1 - 1.4e-69 230.4 0.0 4.3e-09 36.6 0.0 23.7 26 0 0 26 26 24 10 Immunoglobulin domain V-set PF07686.17 RJW67287.1 - 4.1e-58 194.3 0.0 9.9e-06 25.7 0.0 27.8 27 4 0 27 27 26 8 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 RJW67287.1 - 3.7e-46 155.6 44.3 0.079 13.5 0.0 33.5 37 0 0 37 37 33 7 Purple acid Phosphatase, N-terminal domain Pkinase PF00069.25 RJW67287.1 - 3.5e-26 92.1 0.0 7.8e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SusE PF14292.6 RJW67287.1 - 6.8e-22 77.7 16.0 0.49 10.6 0.0 16.9 18 1 1 19 19 17 5 SusE outer membrane protein Tissue_fac PF01108.17 RJW67287.1 - 3.2e-20 72.0 9.0 0.0057 16.5 0.0 11.8 14 0 0 14 14 14 5 Tissue factor C2-set_2 PF08205.12 RJW67287.1 - 2.9e-12 46.5 19.0 0.053 13.6 0.1 12.6 17 0 0 17 17 14 3 CD80-like C2-set immunoglobulin domain Pkinase_Tyr PF07714.17 RJW67287.1 - 3e-12 46.4 0.0 6.4e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase BiPBP_C PF06832.12 RJW67287.1 - 2.2e-11 43.6 0.8 0.28 11.3 0.0 11.4 14 0 0 14 14 13 1 Penicillin-Binding Protein C-terminus Family DUF2369 PF10179.9 RJW67287.1 - 9.9e-10 38.7 0.0 6 7.3 0.0 10.9 13 0 0 13 13 11 1 Uncharacterised conserved protein (DUF2369) Izumo-Ig PF16706.5 RJW67287.1 - 4.2e-06 26.7 3.1 39 4.4 0.0 10.1 12 0 0 12 12 10 0 Izumo-like Immunoglobulin domain Interfer-bind PF09294.10 RJW67287.1 - 9.9e-06 25.8 0.0 23 5.4 0.0 8.4 9 0 0 9 9 8 0 Interferon-alpha/beta receptor, fibronectin type III Kinase-like PF14531.6 RJW67287.1 - 2.5e-05 23.8 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Herpes_gE PF02480.16 RJW67287.1 - 0.013 14.2 0.9 48 2.5 0.0 6.1 8 0 0 8 8 8 0 Alphaherpesvirus glycoprotein E PilX PF13681.6 RJW67287.1 - 0.028 14.8 4.6 0.21 12.0 0.0 5.3 6 0 0 6 6 1 0 Type IV pilus assembly protein PilX C-term Kdo PF06293.14 RJW67287.1 - 0.087 12.2 0.6 0.17 11.3 0.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EpoR_lig-bind PF09067.10 RJW67287.1 - 0.14 12.4 0.1 26 5.1 0.0 2.7 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding VP9 PF09625.10 RJW67290.1 - 0.043 14.0 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 VP9 protein SRCR PF00530.18 RJW67295.1 - 3.9e-27 94.7 6.8 4.3e-14 52.8 1.4 3.4 3 1 0 3 3 3 2 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.23 RJW67295.1 - 2.6e-26 93.0 0.0 4e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR_2 PF15494.6 RJW67295.1 - 5.3e-08 33.3 0.3 0.014 16.0 0.1 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 RJW67295.1 - 0.0067 16.9 0.2 0.18 12.3 0.1 2.4 2 0 0 2 2 2 1 Hepsin, SRCR domain L_HMGIC_fpl PF10242.9 RJW67297.1 - 2e-25 90.1 6.3 8.7e-25 88.0 6.3 2.0 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 RJW67297.1 - 3.5e-06 26.9 5.4 6.9e-06 25.9 5.4 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DuoxA PF10204.9 RJW67297.1 - 0.074 12.0 7.0 0.13 11.3 7.0 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF758 PF05527.11 RJW67298.1 - 5.8e-48 163.3 2.6 7.5e-48 162.9 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF758) PIP5K PF01504.18 RJW67299.1 - 3.6e-68 229.8 0.1 4.8e-68 229.3 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Asp PF00026.23 RJW67301.1 - 6e-20 71.9 0.0 7.2e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW67301.1 - 3.6e-07 30.1 0.1 3.1e-05 23.8 0.1 2.1 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Neur_chan_LBD PF02931.23 RJW67302.1 - 0.0085 15.5 0.1 0.0095 15.4 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain HECW1_helix PF18436.1 RJW67302.1 - 0.14 12.2 1.0 0.2 11.8 0.5 1.5 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 E1_DerP2_DerF2 PF02221.15 RJW67303.1 - 2.8e-14 53.7 0.1 4.1e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 RJW67304.1 - 2.1e-08 34.7 0.0 3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 ML domain Tetraspanin PF00335.20 RJW67306.1 - 1.9e-39 135.7 21.2 2.2e-39 135.5 21.2 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2157 PF09925.9 RJW67306.1 - 0.0057 16.4 0.0 0.027 14.3 0.0 1.9 1 1 1 2 2 2 1 Predicted membrane protein (DUF2157) GPAT_N PF14829.6 RJW67306.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal JIP_LZII PF16471.5 RJW67307.1 - 3.3e-22 78.4 2.5 3.3e-22 78.4 2.5 2.8 3 1 1 4 4 3 1 JNK-interacting protein leucine zipper II Spc7 PF08317.11 RJW67307.1 - 0.00018 20.5 5.6 0.00033 19.6 5.6 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 RJW67307.1 - 0.00033 20.9 14.4 0.0068 16.6 0.1 3.1 2 1 1 3 3 3 2 JNK_SAPK-associated protein-1 RILP PF11461.8 RJW67307.1 - 0.0068 16.6 0.5 0.0068 16.6 0.5 1.8 2 0 0 2 2 1 1 Rab interacting lysosomal protein DUF745 PF05335.13 RJW67307.1 - 0.01 15.5 1.2 0.019 14.7 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) CCDC92 PF14916.6 RJW67307.1 - 0.027 14.2 0.3 1.5 8.6 0.0 3.1 3 0 0 3 3 3 0 Coiled-coil domain of unknown function EzrA PF06160.12 RJW67307.1 - 0.16 10.1 4.3 0.24 9.5 4.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2968 PF11180.8 RJW67307.1 - 0.2 11.3 3.1 0.35 10.5 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Ly49 PF08391.10 RJW67307.1 - 0.27 11.6 0.8 0.51 10.7 0.8 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4407 PF14362.6 RJW67307.1 - 0.31 10.3 1.8 0.52 9.6 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SHE3 PF17078.5 RJW67307.1 - 0.56 9.9 10.0 3.4 7.3 8.2 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 HMMR_N PF15905.5 RJW67307.1 - 0.75 9.2 9.9 1.4 8.4 9.9 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 RJW67307.1 - 0.86 9.0 7.3 1.6 8.1 7.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 TSC22 PF01166.18 RJW67307.1 - 1.4 9.3 8.9 5.9 7.3 0.2 3.6 3 1 0 3 3 3 0 TSC-22/dip/bun family BRE1 PF08647.11 RJW67307.1 - 2.6 8.2 7.2 6.6 6.9 5.1 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ZapB PF06005.12 RJW67307.1 - 2.8 8.4 15.7 12 6.4 5.6 3.9 2 1 1 3 3 3 0 Cell division protein ZapB RVT_1 PF00078.27 RJW67308.1 - 7.1e-45 153.2 0.0 1.1e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Jnk-SapK_ap_N PF09744.9 RJW67308.1 - 3.5e-24 85.8 0.3 5.9e-24 85.1 0.3 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Exo_endo_phos PF03372.23 RJW67308.1 - 3.5e-05 23.4 0.2 0.00013 21.6 0.1 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 RJW67309.1 - 1.4e-46 158.8 0.0 2.4e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) vATP-synt_E PF01991.18 RJW67309.1 - 2.1e-44 151.3 1.2 1e-43 149.1 0.9 1.9 2 0 0 2 2 2 1 ATP synthase (E/31 kDa) subunit Cnd1_N PF12922.7 RJW67309.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Trypsin PF00089.26 RJW67310.1 - 3.2e-59 200.4 0.0 2.9e-58 197.3 0.0 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RJW67310.1 - 3.7e-06 27.9 0.0 5.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 RJW67310.1 - 0.051 14.0 0.0 0.19 12.1 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Cnd2 PF05786.14 RJW67310.1 - 1.3 7.6 6.6 1.7 7.2 6.6 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 BUD22 PF09073.10 RJW67310.1 - 1.5 8.1 4.1 2.1 7.6 4.1 1.2 1 0 0 1 1 1 0 BUD22 E1_DerP2_DerF2 PF02221.15 RJW67312.1 - 2.9e-07 31.0 0.0 4.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 ML domain Complex1_49kDa PF00346.19 RJW67314.1 - 3.1e-121 403.6 0.0 5e-121 402.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit V-SNARE_C PF12352.8 RJW67314.1 - 1.1e-10 41.7 3.7 1.1e-10 41.6 1.3 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RJW67314.1 - 0.00059 19.7 0.3 0.0035 17.2 0.1 2.3 2 0 0 2 2 2 1 Sec20 XRCC4 PF06632.12 RJW67314.1 - 0.035 13.0 0.1 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Hydantoinase_B PF02538.14 RJW67314.1 - 0.057 11.8 0.0 0.094 11.1 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase NiFeSe_Hases PF00374.19 RJW67314.1 - 0.071 12.0 0.1 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Nickel-dependent hydrogenase JHD PF17811.1 RJW67318.1 - 0.00062 20.3 0.3 0.00062 20.3 0.3 3.7 3 1 1 4 4 4 1 Jumonji helical domain PTH2 PF01981.16 RJW67318.1 - 0.063 13.6 7.7 0.2 11.9 7.7 1.9 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 SH2 PF00017.24 RJW67320.1 - 7.7e-10 38.7 0.0 2.8e-09 36.9 0.0 2.1 1 0 0 1 1 1 1 SH2 domain Syntaxin-6_N PF09177.11 RJW67320.1 - 0.41 11.2 2.3 0.5 11.0 0.1 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal LnmK_N_HDF PF18238.1 RJW67320.1 - 0.47 10.2 3.8 0.21 11.4 0.7 2.0 2 0 0 2 2 2 0 LnmK N-terminal Hot Dog Fold domain RasGAP_C PF03836.15 RJW67320.1 - 9.3 6.4 9.6 1.9 8.6 2.1 2.7 2 1 0 2 2 2 0 RasGAP C-terminus NMT_C PF02799.15 RJW67321.1 - 1.5e-76 256.6 0.6 2.2e-76 256.0 0.6 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 RJW67321.1 - 2.2e-73 245.3 0.0 3.4e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Asp PF00026.23 RJW67321.1 - 5.1e-33 114.8 0.7 2.5e-19 69.8 0.2 3.1 3 0 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW67321.1 - 3.1e-08 34.1 0.2 5.9e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Acetyltransf_1 PF00583.25 RJW67321.1 - 0.0015 18.8 0.0 0.0044 17.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 RJW67321.1 - 0.085 12.9 0.0 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ig_3 PF13927.6 RJW67323.1 - 5.9e-11 42.8 0.4 0.13 12.9 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 RJW67323.1 - 2.3e-06 27.7 0.2 0.062 13.5 0.1 4.3 3 1 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 RJW67323.1 - 0.00011 22.3 1.7 9.1 6.5 0.0 4.9 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 RJW67323.1 - 0.0011 18.9 0.0 4.4 7.4 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin I-set domain Pkinase PF00069.25 RJW67324.1 - 5.7e-57 193.1 0.0 8.9e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67324.1 - 2.2e-38 132.0 0.0 3.3e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW67324.1 - 1.5e-08 33.8 0.3 3.9e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 RJW67324.1 - 1.5e-05 24.7 2.6 0.00012 21.8 2.6 2.2 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 RJW67324.1 - 4.9e-05 23.4 0.0 0.0019 18.2 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW67324.1 - 0.0009 18.3 3.5 0.0028 16.7 0.1 2.2 2 0 0 2 2 2 1 Haspin like kinase domain PHTB1_N PF14727.6 RJW67325.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 PTHB1 N-terminus Tetraspanin PF00335.20 RJW67326.1 - 7.2e-25 88.0 7.1 8.6e-25 87.8 7.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Saf_2TM PF18303.1 RJW67326.1 - 0.096 12.3 2.7 0.12 11.9 0.4 2.2 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain Phage_holin_2_4 PF16082.5 RJW67326.1 - 7.1 6.4 5.8 0.79 9.5 0.9 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Sid-5 PF17204.3 RJW67326.1 - 7.9 6.7 6.5 0.95 9.7 1.7 2.0 2 0 0 2 2 2 0 Sid-5 family PTEN_C2 PF10409.9 RJW67327.1 - 0.056 13.2 0.1 0.25 11.1 0.1 2.0 1 1 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Ras PF00071.22 RJW67328.1 - 1.2e-30 106.3 0.2 1.3e-30 106.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW67328.1 - 6.7e-12 45.7 0.1 1.2e-11 44.8 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW67328.1 - 0.0035 16.8 0.0 0.0037 16.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family TTL PF03133.15 RJW67329.1 - 3.5e-84 282.4 0.9 9.7e-84 281.0 0.0 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RJW67329.1 - 4.4e-06 26.1 0.0 7.3e-05 22.1 0.0 2.5 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RJW67329.1 - 0.0032 16.8 0.0 0.0072 15.6 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp DNA_ligase_A_N PF04675.14 RJW67329.1 - 0.024 14.9 0.0 0.092 13.1 0.0 2.0 1 1 0 1 1 1 0 DNA ligase N terminus UPF0242 PF06785.11 RJW67329.1 - 2.9 7.9 6.1 10 6.2 6.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran PF00005.27 RJW67330.1 - 7e-24 84.9 0.0 9.9e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RJW67330.1 - 6.2e-07 29.5 0.0 0.00087 19.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RJW67330.1 - 1.7e-06 27.6 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RJW67330.1 - 0.0035 17.3 0.1 0.0066 16.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 RJW67330.1 - 0.012 15.8 0.0 0.21 11.8 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 RJW67330.1 - 0.092 11.4 0.0 0.5 8.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain IL7 PF01415.16 RJW67330.1 - 0.11 12.5 0.5 0.62 10.1 0.1 2.0 2 0 0 2 2 2 0 Interleukin 7/9 family Asp PF00026.23 RJW67331.1 - 8e-15 55.1 0.0 9.4e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease AA_permease_2 PF13520.6 RJW67332.1 - 8.1e-42 143.5 21.0 8.1e-42 143.5 21.0 2.3 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 RJW67332.1 - 3.5e-28 98.5 22.7 3.5e-28 98.5 22.7 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RJW67332.1 - 7.2e-17 61.2 8.8 7.2e-17 61.2 8.8 3.5 4 0 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.13 RJW67332.1 - 0.00072 18.5 2.0 0.00072 18.5 2.0 3.8 4 0 0 4 4 4 2 Spore germination protein DUF5084 PF16894.5 RJW67332.1 - 0.036 14.5 5.7 2.1 8.8 1.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5084) DUF3377 PF11857.8 RJW67332.1 - 0.37 10.7 1.9 1.1 9.2 1.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) MYCBPAP PF14646.6 RJW67333.1 - 1.8e-67 228.2 0.8 2.6e-67 227.7 0.8 1.1 1 0 0 1 1 1 1 MYCBP-associated protein family I-set PF07679.16 RJW67334.1 - 7.4e-67 221.5 0.4 1.8e-17 63.2 0.0 9.1 9 0 0 9 9 9 8 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW67334.1 - 2.5e-51 172.2 2.1 4.6e-10 40.0 0.0 9.3 8 1 0 8 8 8 8 Immunoglobulin domain V-set PF07686.17 RJW67334.1 - 4.9e-24 84.6 10.3 0.0041 17.3 0.0 10.1 8 4 0 8 8 8 6 Immunoglobulin V-set domain Ig_2 PF13895.6 RJW67334.1 - 8.8e-24 83.6 12.9 0.00026 21.3 0.4 8.5 8 1 0 8 8 8 6 Immunoglobulin domain ig PF00047.25 RJW67334.1 - 7.8e-22 77.3 11.6 0.0053 16.9 0.0 8.8 8 0 0 8 8 8 6 Immunoglobulin domain Izumo-Ig PF16706.5 RJW67334.1 - 0.00014 21.8 3.7 13 5.9 0.0 5.4 5 1 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RJW67334.1 - 0.00041 19.8 0.2 3.3 7.4 0.0 4.6 4 0 0 4 4 4 1 Immunoglobulin domain Receptor_2B4 PF11465.8 RJW67334.1 - 0.0026 17.9 0.2 21 5.4 0.0 5.0 7 0 0 7 7 7 0 Natural killer cell receptor 2B4 Syntaxin-6_N PF09177.11 RJW67334.1 - 5.6 7.6 9.5 8 7.1 0.1 4.2 2 1 2 4 4 4 0 Syntaxin 6, N-terminal CDV3 PF15359.6 RJW67338.1 - 2.1e-09 38.0 4.8 2.1e-09 38.0 4.8 2.9 2 1 0 2 2 2 2 Carnitine deficiency-associated protein 3 Kunitz_BPTI PF00014.23 RJW67339.1 - 3e-07 30.6 6.8 4.2e-07 30.1 6.8 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 RJW67340.1 - 1.9e-12 47.2 7.9 2.8e-12 46.7 7.9 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain MRP-S34 PF16053.5 RJW67340.1 - 0.053 13.2 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 Kinesin PF00225.23 RJW67341.1 - 3e-87 292.6 0.0 8.9e-87 291.1 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW67341.1 - 2.5e-14 53.5 6.6 4.5e-14 52.6 0.0 3.8 4 1 0 4 4 4 1 Microtubule binding SlyX PF04102.12 RJW67341.1 - 0.0092 16.6 4.5 0.0092 16.6 4.5 4.8 3 2 1 4 4 4 1 SlyX bZIP_1 PF00170.21 RJW67341.1 - 2.3 8.4 16.4 2.5 8.3 0.9 3.3 3 0 0 3 3 3 0 bZIP transcription factor ADIP PF11559.8 RJW67341.1 - 6.8 6.8 33.7 0.12 12.5 3.7 3.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Kunitz_BPTI PF00014.23 RJW67342.1 - 2.1e-20 72.7 6.0 3.1e-20 72.1 6.0 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF1794 PF08768.11 RJW67343.1 - 0.46 10.4 3.5 6.7 6.6 3.5 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1794) HEPN_AbiA_CTD PF18732.1 RJW67343.1 - 0.62 10.0 10.6 0.31 11.0 0.1 4.4 5 0 0 5 5 5 0 HEPN like, Abia C-terminal domain Pkinase PF00069.25 RJW67344.1 - 2.5e-08 33.6 0.0 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67344.1 - 2.9e-07 30.0 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 RJW67344.1 - 6.7e-06 26.3 0.1 1.8e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW67344.1 - 0.0042 17.7 0.0 0.0095 16.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RJW67344.1 - 0.0062 16.9 0.2 0.0062 16.9 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RJW67344.1 - 0.011 16.3 0.0 0.033 14.8 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW67344.1 - 0.19 12.4 0.0 0.58 10.9 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat START PF01852.19 RJW67345.1 - 7.1e-32 110.5 0.1 9.1e-32 110.2 0.1 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 RJW67345.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) DHFR_1 PF00186.19 RJW67346.1 - 9.9e-24 83.9 0.0 6.1e-22 78.0 0.0 2.0 2 0 0 2 2 2 2 Dihydrofolate reductase His_Phos_1 PF00300.22 RJW67347.1 - 2.2e-32 112.3 0.0 2.2e-29 102.5 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1041 PF06292.17 RJW67348.1 - 4.1e-26 91.4 0.9 1.1e-25 90.1 0.9 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) C2 PF00168.30 RJW67348.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 RJW67348.1 - 0.0034 17.9 0.2 0.042 14.4 0.0 2.6 2 1 0 2 2 2 1 PH domain Gp5_C PF06715.12 RJW67349.1 - 2.1e-20 71.3 62.8 1.8e+04 -51.2 62.8 21.0 1 1 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) DUF445 PF04286.12 RJW67349.1 - 2.6e-14 53.8 65.9 7.1e-07 29.3 31.6 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF445) GerPC PF10737.9 RJW67349.1 - 1e-06 28.9 51.8 1.8e+04 -29.3 51.8 5.2 1 1 0 1 1 1 0 Spore germination protein GerPC DUF2884 PF11101.8 RJW67349.1 - 0.0039 16.7 116.0 1.8e+04 -85.1 116.0 8.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) EcsC PF12787.7 RJW67349.1 - 0.0044 16.7 58.1 1.8e+04 -42.8 58.0 8.1 1 1 0 1 1 1 0 EcsC protein family DUF3819 PF12842.7 RJW67349.1 - 0.0048 16.9 74.8 1.8e+04 -49.2 74.8 7.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3819) CEL_III_C PF18054.1 RJW67349.1 - 0.01 15.9 202.8 1.8e+04 -163.8 202.8 9.1 1 1 0 1 1 1 0 CEL-III C-terminal RHD3 PF05879.12 RJW67349.1 - 0.14 10.2 81.5 2.7 6.0 22.6 3.5 1 1 1 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) Kunitz_BPTI PF00014.23 RJW67350.1 - 5.3e-17 61.8 9.7 7.1e-17 61.4 9.7 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain PG_binding_2 PF08823.11 RJW67350.1 - 0.11 12.8 0.0 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Putative peptidoglycan binding domain MRP-L47 PF06984.13 RJW67351.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2120 PF09893.9 RJW67354.1 - 0.1 12.7 5.5 0.048 13.8 2.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) ATP-synt_B PF00430.18 RJW67354.1 - 1.3 9.1 4.5 2.5 8.2 0.6 2.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) CxC4 PF18717.1 RJW67355.1 - 0.22 11.4 5.1 0.22 11.3 2.8 2.2 1 1 1 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases Kunitz_BPTI PF00014.23 RJW67357.1 - 5.5e-05 23.3 6.1 8.1e-05 22.8 6.1 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain TTKRSYEDQ PF10212.9 RJW67358.1 - 7e-05 22.0 0.5 7.8e-05 21.9 0.5 1.0 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein MINDY_DUB PF04424.13 RJW67358.1 - 0.0006 19.8 0.1 0.00095 19.2 0.1 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase ATG16 PF08614.11 RJW67358.1 - 0.0037 17.5 1.6 1.3 9.2 0.1 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF262 PF03235.14 RJW67358.1 - 0.018 15.2 0.1 0.023 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF5327 PF17261.2 RJW67358.1 - 0.041 14.6 0.1 0.072 13.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5327) zf-C2H2 PF00096.26 RJW67360.1 - 3e-10 40.0 24.5 0.00027 21.2 2.9 4.3 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW67360.1 - 1.9e-07 31.3 17.7 0.017 15.9 1.9 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW67360.1 - 0.00015 21.7 11.5 0.064 13.3 0.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW67360.1 - 0.00019 21.7 1.0 0.00019 21.7 1.0 4.4 3 1 1 4 4 4 1 Zinc-finger double domain zf-FCS PF06467.14 RJW67360.1 - 0.18 11.8 3.8 3.5 7.6 0.1 2.7 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf_UBZ PF18439.1 RJW67360.1 - 0.77 9.4 4.4 2.3 7.9 0.9 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 RJW67360.1 - 0.92 9.9 11.2 15 6.0 0.2 3.5 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 RJW67360.1 - 1.1 9.8 15.1 0.2 12.1 0.6 3.5 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-CHY PF05495.12 RJW67360.1 - 1.4 9.5 11.8 5.9 7.5 10.5 2.5 1 1 1 2 2 2 0 CHY zinc finger C1_4 PF07975.12 RJW67360.1 - 1.9 8.8 5.8 0.45 10.8 1.7 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain C1_2 PF03107.16 RJW67360.1 - 2.5 8.5 6.3 4.9 7.6 2.7 2.7 2 1 0 2 2 2 0 C1 domain GAGA PF09237.11 RJW67360.1 - 8 6.4 8.6 3.6 7.5 1.6 3.1 2 1 1 3 3 3 0 GAGA factor DUF4495 PF14906.6 RJW67361.1 - 1.5e-05 24.2 0.8 0.00027 20.1 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4495) 60KD_IMP PF02096.20 RJW67362.1 - 0.00071 19.5 4.3 0.001 19.0 4.3 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein B56 PF01603.20 RJW67363.1 - 1.9e-187 623.3 4.4 2.3e-187 623.1 4.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 RJW67363.1 - 0.044 13.7 3.7 0.56 10.1 0.2 2.9 1 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4253 PF14062.6 RJW67364.1 - 0.082 13.1 0.0 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Pyr_redox_2 PF07992.14 RJW67365.1 - 0.00049 19.4 0.0 0.0025 17.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SHIPPO-rpt PF07004.12 RJW67366.1 - 1.1e-21 76.6 28.6 4.8e-07 30.4 0.4 6.1 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat His_Phos_1 PF00300.22 RJW67367.1 - 2.5e-17 63.2 0.0 1.2e-08 34.9 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Osteoregulin PF07175.11 RJW67367.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Osteoregulin AtuA PF07287.11 RJW67367.1 - 0.14 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA SH3_1 PF00018.28 RJW67368.1 - 5.3e-32 109.2 0.1 1.1e-17 63.3 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 RJW67368.1 - 6.6e-31 105.9 0.4 3.4e-16 58.8 0.1 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 RJW67368.1 - 1.9e-25 88.3 0.0 7e-16 57.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 RJW67368.1 - 4e-17 62.1 0.0 7.5e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 RJW67368.1 - 0.0083 16.4 0.2 6.8 7.1 0.1 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain DUF5348 PF17295.2 RJW67368.1 - 0.0096 15.8 1.3 0.61 10.0 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF5348) DUF4648 PF15505.6 RJW67368.1 - 0.045 14.6 0.0 0.29 12.0 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4648) SH3_10 PF17902.1 RJW67368.1 - 0.07 13.2 0.0 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 SH3 domain PAN_1 PF00024.26 RJW67369.1 - 4.1e-06 26.7 0.4 6.9e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 PAN domain Melibiase_2 PF16499.5 RJW67369.1 - 0.049 12.8 0.1 0.054 12.7 0.1 1.1 1 0 0 1 1 1 0 Alpha galactosidase A PAN_1 PF00024.26 RJW67370.1 - 5.7e-05 23.0 0.4 5.9e-05 22.9 0.4 1.1 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RJW67370.1 - 0.0056 16.6 1.9 0.012 15.4 1.9 1.7 1 1 0 1 1 1 1 PAN domain WW_1 PF18507.1 RJW67370.1 - 0.029 14.1 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 WW domain VWA_3 PF13768.6 RJW67371.1 - 1.4e-28 99.8 0.0 1.3e-10 41.4 0.0 4.7 5 1 0 5 5 5 3 von Willebrand factor type A domain VWA_2 PF13519.6 RJW67371.1 - 3.6e-10 40.5 0.0 0.0013 19.4 0.0 4.3 3 1 0 3 3 3 3 von Willebrand factor type A domain VWA PF00092.28 RJW67371.1 - 9.4e-10 39.0 0.0 0.00068 19.9 0.0 3.7 3 1 0 3 3 3 2 von Willebrand factor type A domain Tau95 PF09734.9 RJW67371.1 - 0.091 13.6 0.0 12 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Guanylate_cyc PF00211.20 RJW67373.1 - 2.2e-98 327.3 1.5 8.7e-55 185.2 0.3 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain zf-H2C2_2 PF13465.6 RJW67374.1 - 4.1e-33 112.3 39.8 4.2e-07 30.1 1.9 7.6 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 RJW67374.1 - 2.4e-23 81.2 40.0 0.00088 19.6 0.7 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW67374.1 - 2.9e-21 74.3 36.4 0.0015 19.2 0.9 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW67374.1 - 1.6e-17 63.2 16.2 0.0004 20.6 0.0 6.4 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW67374.1 - 1.7e-10 40.6 32.2 0.028 14.4 0.2 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-Di19 PF05605.12 RJW67374.1 - 3.7e-05 23.9 19.3 0.01 16.1 1.7 4.1 2 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RJW67374.1 - 6.7e-05 23.1 24.0 0.058 13.8 0.1 6.2 6 1 0 6 6 6 2 Zinc-finger of C2H2 type zf-BED PF02892.15 RJW67374.1 - 0.042 13.9 21.3 5 7.2 0.2 4.9 2 2 2 4 4 4 0 BED zinc finger C1_1 PF00130.22 RJW67374.1 - 0.17 11.8 14.7 3.8 7.5 1.8 4.1 2 2 3 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_4 PF07975.12 RJW67374.1 - 0.3 11.4 14.7 2.7 8.3 0.6 4.1 2 1 1 4 4 4 0 TFIIH C1-like domain DUF3268 PF11672.8 RJW67374.1 - 4.8 7.5 7.8 1.1 9.6 1.1 2.6 1 1 1 3 3 3 0 zinc-finger-containing domain zf-C2H2_3rep PF18868.1 RJW67374.1 - 5.7 7.6 13.0 2.5 8.8 0.1 4.5 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats Zf_RING PF16744.5 RJW67374.1 - 8.9 6.5 11.9 15 5.8 0.4 4.3 2 2 2 4 4 4 0 KIAA1045 RING finger RVT_1 PF00078.27 RJW67376.1 - 9.4e-09 35.1 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Thioredoxin PF00085.20 RJW67378.1 - 4.5e-06 26.6 0.0 8.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin RYDR_ITPR PF01365.21 RJW67378.1 - 0.018 14.4 0.3 0.025 14.0 0.3 1.1 1 0 0 1 1 1 0 RIH domain RapA_C PF12137.8 RJW67378.1 - 0.23 10.4 5.2 0.3 10.1 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal PAN_1 PF00024.26 RJW67379.1 - 0.0078 16.2 1.0 0.021 14.8 1.0 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 RJW67380.1 - 0.0004 20.3 1.4 0.0008 19.3 1.4 1.5 1 0 0 1 1 1 1 PAN domain WW_1 PF18507.1 RJW67380.1 - 0.14 11.8 0.1 0.35 10.6 0.0 1.6 2 0 0 2 2 2 0 WW domain VKOR PF07884.14 RJW67381.1 - 5.9 7.1 16.9 6.8 6.9 16.9 1.1 1 0 0 1 1 1 0 Vitamin K epoxide reductase family DUF805 PF05656.14 RJW67381.1 - 8.8 6.8 14.0 10 6.6 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) MOZ_SAS PF01853.18 RJW67383.1 - 2.4e-69 232.6 0.1 3.9e-69 231.9 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RJW67383.1 - 2.8e-20 71.7 1.7 1.5e-19 69.3 1.7 2.3 1 0 0 1 1 1 1 MYST family zinc finger domain PHD PF00628.29 RJW67383.1 - 3.2e-16 59.0 15.5 6.1e-10 38.8 3.7 3.2 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 RJW67383.1 - 5.1e-06 26.5 15.7 0.00029 20.8 2.3 2.7 1 1 1 2 2 2 2 PHD-finger Vps36-NZF-N PF16988.5 RJW67383.1 - 0.12 11.8 0.1 0.12 11.8 0.1 3.3 3 1 1 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Neur_chan_LBD PF02931.23 RJW67384.1 - 3.8e-45 154.0 0.3 6.7e-45 153.2 0.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DnaJ_C PF01556.18 RJW67385.1 - 3.5e-40 137.5 0.0 5.5e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RJW67385.1 - 4.4e-25 87.6 1.6 7.2e-25 86.9 1.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RJW67385.1 - 1.9e-13 50.6 20.5 3.1e-13 49.9 20.5 1.4 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.10 RJW67385.1 - 2.3 8.0 9.7 11 5.9 2.9 3.5 2 1 1 3 3 3 0 A2L zinc ribbon domain PHD PF00628.29 RJW67386.1 - 8.6e-08 32.0 8.7 8.6e-08 32.0 8.7 2.0 2 0 0 2 2 2 1 PHD-finger WSD PF15613.6 RJW67386.1 - 0.14 12.6 0.0 0.14 12.6 0.0 3.1 3 1 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD_2 PF13831.6 RJW67386.1 - 0.34 10.5 4.5 0.13 11.9 0.5 2.5 3 0 0 3 3 3 0 PHD-finger L_HMGIC_fpl PF10242.9 RJW67389.1 - 3e-27 96.0 9.1 1.1e-25 90.9 9.1 2.1 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 RJW67389.1 - 2.6e-10 40.4 2.1 4.8e-10 39.5 2.1 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Frag1 PF10277.9 RJW67390.1 - 1.2e-24 87.1 17.4 1.4e-24 86.8 17.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family PET117 PF15786.5 RJW67390.1 - 0.2 12.0 2.0 0.31 11.3 0.2 2.2 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Neur_chan_memb PF02932.16 RJW67391.1 - 1.9e-25 90.3 0.0 1.1e-20 74.7 0.4 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro_31 PF01055.26 RJW67392.1 - 3.5e-148 494.5 0.0 4.6e-148 494.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RJW67392.1 - 9.2e-18 64.5 0.0 1.9e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 RJW67392.1 - 1.1e-08 34.8 4.7 1.1e-08 34.8 4.7 1.7 2 0 0 2 2 2 1 Trefoil (P-type) domain Filament PF00038.21 RJW67395.1 - 0.18 11.3 33.6 0.086 12.4 6.9 2.9 2 1 1 3 3 3 0 Intermediate filament protein DUF4250 PF14056.6 RJW67395.1 - 0.2 11.7 2.2 16 5.6 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) DUF5446 PF17522.2 RJW67395.1 - 8.2 6.7 23.0 7.1 6.9 7.6 3.9 3 1 0 3 3 3 0 Family of unknown function (DUF5446) NPV_P10 PF05531.12 RJW67395.1 - 8.4 6.9 10.1 10 6.7 0.2 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PRP38 PF03371.15 RJW67396.1 - 1.4e-56 191.1 0.0 1.8e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Ion_trans PF00520.31 RJW67397.1 - 5.3e-36 124.1 14.0 9.3e-36 123.3 14.0 1.4 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RJW67397.1 - 9.9e-26 89.9 0.0 2.4e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RJW67397.1 - 1.1e-12 47.7 9.5 1.1e-12 47.7 9.5 2.5 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 RJW67397.1 - 1.7e-05 24.8 0.0 5.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Shal-type PF11601.8 RJW67397.1 - 0.0019 17.7 2.9 0.0033 16.9 2.9 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal DUF3399 PF11879.8 RJW67397.1 - 0.0068 16.7 0.1 0.019 15.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3399) PKD_channel PF08016.12 RJW67397.1 - 0.074 11.7 6.3 0.11 11.1 6.3 1.3 1 0 0 1 1 1 0 Polycystin cation channel zf-C2H2 PF00096.26 RJW67398.1 - 0.00075 19.8 25.1 0.0026 18.1 6.1 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW67398.1 - 0.00094 19.8 23.0 0.039 14.8 4.7 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RJW67398.1 - 0.0022 18.3 4.5 0.71 10.2 0.2 3.3 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 RJW67398.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.7 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_4 PF13717.6 RJW67398.1 - 0.33 10.9 2.0 56 3.8 0.0 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 RJW67398.1 - 0.73 9.6 3.7 6.8 6.5 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-BED PF02892.15 RJW67398.1 - 9.1 6.4 12.9 1.2 9.2 0.9 3.3 4 0 0 4 4 4 0 BED zinc finger Frag1 PF10277.9 RJW67400.1 - 8.7e-27 94.1 22.4 8.7e-27 94.1 22.4 1.4 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family DUF21 PF01595.20 RJW67400.1 - 0.0066 16.2 0.2 0.0066 16.2 0.2 2.0 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain Pkinase PF00069.25 RJW67403.1 - 1.8e-61 207.8 0.0 3.3e-39 134.9 0.6 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67403.1 - 4.3e-36 124.5 0.0 1.3e-23 83.7 0.4 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RJW67403.1 - 2e-05 24.1 0.0 0.087 12.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 RJW67403.1 - 0.0046 16.3 0.2 0.008 15.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RJW67403.1 - 0.085 12.4 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 RJW67403.1 - 5.6 5.6 9.6 0.13 11.0 2.4 2.0 2 1 0 2 2 2 0 Fungal protein kinase DIX PF00778.17 RJW67406.1 - 9.3e-29 99.1 0.9 8.3e-27 92.8 0.9 2.4 1 1 0 1 1 1 1 DIX domain Dishevelled PF02377.15 RJW67406.1 - 2.9e-26 92.8 14.1 2.9e-26 92.8 14.1 3.5 3 0 0 3 3 3 1 Dishevelled specific domain PDZ PF00595.24 RJW67406.1 - 9.3e-18 64.4 0.6 1.9e-17 63.4 0.6 1.5 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 RJW67406.1 - 7.6e-17 61.1 0.1 1.9e-16 59.9 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 RJW67406.1 - 7.2e-05 22.5 0.1 0.00014 21.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW67406.1 - 0.011 16.1 0.5 0.031 14.6 0.1 2.0 2 0 0 2 2 2 0 PDZ domain NDUFA12 PF05071.16 RJW67407.1 - 1.4 9.9 4.5 2.1 9.3 0.2 2.7 3 0 0 3 3 3 0 NADH ubiquinone oxidoreductase subunit NDUFA12 ARID PF01388.21 RJW67408.1 - 7.9e-10 39.3 0.0 2.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.25 RJW67409.1 - 9.1e-39 133.4 0.0 1.4e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67409.1 - 1.5e-17 63.8 0.0 2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW67409.1 - 4.4e-08 32.8 0.0 1.5e-05 24.5 0.0 2.4 1 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 RJW67409.1 - 0.00095 18.2 0.3 0.0016 17.5 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RJW67409.1 - 0.01 15.8 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RJW67409.1 - 0.11 11.8 0.3 0.19 11.1 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RJW67409.1 - 0.15 10.8 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase DS PF01916.17 RJW67412.1 - 6.4e-119 396.5 0.0 8.6e-119 396.1 0.0 1.2 1 0 0 1 1 1 1 Deoxyhypusine synthase MRP-S35 PF10246.9 RJW67412.1 - 7.1e-31 106.3 0.0 1.3e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 LRR_8 PF13855.6 RJW67413.1 - 7.2e-18 64.1 28.0 1.2e-09 37.7 1.3 3.8 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 RJW67413.1 - 2.7e-10 40.3 21.7 2.2e-06 27.9 4.5 4.2 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) SAM_2 PF07647.17 RJW67413.1 - 0.00012 22.2 0.0 0.0067 16.5 0.0 2.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RJW67413.1 - 0.0099 16.3 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LRR_1 PF00560.33 RJW67413.1 - 0.034 14.7 12.7 1.2 10.0 0.6 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 RJW67413.1 - 1.2 9.4 6.9 5.4 7.3 0.5 3.7 4 0 0 4 4 4 0 Leucine Rich repeat IMS PF00817.20 RJW67414.1 - 2e-31 109.0 0.0 3.3e-20 72.6 0.0 2.4 2 0 0 2 2 2 2 impB/mucB/samB family RNase_3_N PF18497.1 RJW67414.1 - 0.092 13.0 0.2 7 6.9 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain Ribosomal_S7e PF01251.18 RJW67415.1 - 1e-72 243.8 0.6 1.2e-72 243.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e PAP_central PF04928.17 RJW67417.1 - 1.8e-91 305.5 0.1 2.7e-91 305.0 0.1 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 RJW67417.1 - 8.2e-19 67.9 2.0 5.6e-12 45.6 0.2 2.6 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 RJW67417.1 - 7.5e-07 29.4 0.0 2.2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Bombinin PF05298.11 RJW67417.1 - 0.04 13.6 0.1 6.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Bombinin Longin PF13774.6 RJW67418.1 - 2.1e-10 40.5 0.0 3.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 RJW67418.1 - 9.6e-10 38.1 0.1 1.7e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Ribosomal_L27A PF00828.19 RJW67419.1 - 2.1e-12 47.9 0.0 3.5e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PPTA PF01239.22 RJW67420.1 - 1e-39 133.1 19.6 2e-12 46.4 0.9 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat LRR_9 PF14580.6 RJW67420.1 - 3.5e-06 26.6 0.6 8.6e-06 25.4 0.6 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RJW67420.1 - 2.5e-05 23.9 4.8 0.00029 20.5 1.6 3.6 2 1 2 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 RJW67420.1 - 0.00025 21.4 16.9 0.018 15.5 1.2 4.4 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) TPR_17 PF13431.6 RJW67420.1 - 0.13 12.7 1.6 13 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.6 RJW67420.1 - 3.4 8.0 5.2 23 5.4 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat DUF4821 PF16092.5 RJW67421.1 - 6.3e-75 252.2 0.1 1e-68 231.8 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) SAM_1 PF00536.30 RJW67422.1 - 2.6e-05 24.6 0.0 4.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Atx10homo_assoc PF09759.9 RJW67423.1 - 0.0022 18.0 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Neur_chan_LBD PF02931.23 RJW67424.1 - 2.6e-46 157.8 1.2 6e-46 156.6 1.2 1.6 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW67424.1 - 5e-27 95.5 9.5 3.3e-26 92.8 9.5 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region ODV-E18 PF10717.9 RJW67424.1 - 1.8 8.5 12.3 3 7.8 0.8 3.6 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 PDZ PF00595.24 RJW67425.1 - 8.1e-26 90.2 0.0 9.8e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RJW67425.1 - 8.3e-26 89.6 0.0 5.3e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RJW67425.1 - 2e-14 53.7 0.0 2.8e-06 27.6 0.0 3.2 3 0 0 3 3 3 2 PDZ domain PDZ_4 PF17816.1 RJW67425.1 - 0.00093 19.6 0.0 0.28 11.6 0.0 2.7 1 1 1 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 RJW67425.1 - 0.015 15.3 0.0 0.98 9.4 0.0 2.7 2 1 0 2 2 2 0 Tricorn protease PDZ domain DUF3657 PF12394.8 RJW67426.1 - 2.9e-14 53.3 1.0 2.9e-14 53.3 1.0 2.4 3 0 0 3 3 3 1 Protein FAM135 Brix PF04427.18 RJW67427.1 - 3.6e-22 79.4 0.0 4.8e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain RVT_1 PF00078.27 RJW67428.1 - 2.6e-06 27.1 0.0 5.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C5-epim_C PF06662.13 RJW67429.1 - 9.9e-54 181.7 0.0 3.8e-45 153.7 0.0 2.3 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus ASC PF00858.24 RJW67431.1 - 6.2e-47 160.6 0.0 8.1e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Amelotin PF15757.5 RJW67432.1 - 0.048 13.2 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Amelotin RNA_pol_Rpb2_6 PF00562.28 RJW67433.1 - 4.7e-128 427.6 0.2 6.7e-128 427.1 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 RJW67433.1 - 3.4e-66 222.6 0.0 4.9e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 RJW67433.1 - 7.8e-49 165.9 0.4 1.9e-48 164.6 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 RJW67433.1 - 5.7e-33 113.2 0.1 1.3e-32 112.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 RJW67433.1 - 5.7e-24 84.1 0.0 1.4e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 RJW67433.1 - 1.2e-21 76.7 2.5 1.7e-21 76.3 1.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 RJW67433.1 - 3.9e-16 59.4 1.1 9.9e-16 58.1 1.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RVT_1 PF00078.27 RJW67434.1 - 0.0096 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) fn3 PF00041.21 RJW67435.1 - 2.5e-41 139.9 14.6 9.5e-14 51.5 1.8 7.5 7 1 0 7 7 7 5 Fibronectin type III domain Y_phosphatase PF00102.27 RJW67435.1 - 2.5e-12 46.9 0.5 4.1e-12 46.2 0.5 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pur_ac_phosph_N PF16656.5 RJW67435.1 - 1.4e-08 35.2 3.8 0.0022 18.5 0.0 5.4 5 0 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RJW67435.1 - 4.2e-07 30.2 0.0 0.79 10.1 0.0 4.1 4 0 0 4 4 4 3 Interferon-alpha/beta receptor, fibronectin type III NFACT-R_1 PF05670.13 RJW67436.1 - 3e-38 130.8 0.1 6.1e-27 94.4 0.0 2.3 1 1 1 2 2 2 2 NFACT protein RNA binding domain SIMPL PF04402.14 RJW67436.1 - 0.011 16.2 4.1 0.013 15.9 4.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF541) TFX_C PF14601.6 RJW67436.1 - 0.015 15.3 0.1 0.55 10.2 0.0 2.6 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term DUF2514 PF10721.9 RJW67436.1 - 0.067 13.2 7.1 0.097 12.7 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) PEARLI-4 PF05278.12 RJW67436.1 - 0.38 10.3 7.8 0.65 9.5 7.8 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) RabGAP-TBC PF00566.18 RJW67437.1 - 2.4e-45 154.8 8.4 4e-45 154.1 8.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 RJW67437.1 - 0.0051 16.3 0.0 2.4 7.6 0.0 2.2 1 1 1 2 2 2 2 Rab-binding domain (RBD) Pept_S41_N PF18294.1 RJW67437.1 - 0.014 15.4 0.5 0.044 13.8 0.5 1.9 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain HMG_CoA_synt_N PF01154.17 RJW67438.1 - 2.9e-73 245.5 0.0 4e-73 245.0 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 RJW67438.1 - 3e-71 240.3 0.0 2.1e-68 231.0 0.0 2.1 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 RJW67438.1 - 0.12 12.5 0.0 0.8 9.9 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal EF-hand_6 PF13405.6 RJW67439.1 - 1.6e-20 71.2 6.7 2.8e-08 33.0 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 RJW67439.1 - 7.5e-19 67.9 7.9 1.3e-12 48.0 1.8 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW67439.1 - 5e-18 63.2 13.4 9.6e-10 37.3 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 RJW67439.1 - 5.8e-10 38.2 7.1 1.2e-05 24.5 0.3 4.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 RJW67439.1 - 3.1e-07 30.1 10.4 6.1e-07 29.2 2.0 3.8 3 1 1 4 4 4 1 EF-hand domain pair p25-alpha PF05517.12 RJW67439.1 - 0.00011 22.4 1.2 0.00024 21.3 0.9 1.7 1 1 0 1 1 1 1 p25-alpha EF-hand_4 PF12763.7 RJW67439.1 - 0.0029 17.5 1.7 0.0093 15.9 0.1 2.5 2 1 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 RJW67439.1 - 0.029 14.3 0.6 0.69 9.8 0.2 2.3 1 1 1 2 2 2 0 Caleosin related protein EF-hand_9 PF14658.6 RJW67439.1 - 0.046 14.1 1.8 10 6.5 0.0 3.4 2 1 1 3 3 3 0 EF-hand domain NPA PF16469.5 RJW67439.1 - 0.058 14.0 3.5 0.12 13.0 0.2 2.6 2 1 0 3 3 3 0 Nematode polyprotein allergen ABA-1 EF-hand_13 PF17958.1 RJW67439.1 - 0.1 12.4 0.0 2.7 7.9 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain Neur_chan_LBD PF02931.23 RJW67442.1 - 4.5e-42 143.9 0.1 6.2e-42 143.5 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW67442.1 - 3.8e-29 102.4 0.6 1.2e-23 84.4 0.9 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region LPP PF04728.13 RJW67443.1 - 0.059 13.8 0.2 0.16 12.3 0.2 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Syntaxin-6_N PF09177.11 RJW67443.1 - 2.2 8.9 16.4 1.2 9.7 9.7 3.0 2 2 1 3 3 3 0 Syntaxin 6, N-terminal Med23 PF11573.8 RJW67444.1 - 4.9e-104 349.2 10.7 1.9e-56 191.5 0.0 6.6 6 1 0 6 6 6 6 Mediator complex subunit 23 RVT_1 PF00078.27 RJW67447.1 - 8.9e-09 35.2 0.0 2.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.7 RJW67448.1 - 2.4e-10 40.8 0.0 4.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RJW67448.1 - 6e-09 35.9 0.5 3.3e-05 24.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RJW67448.1 - 4.9e-08 33.1 0.1 3.5e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW67448.1 - 1.1e-07 32.2 0.0 4.6e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW67448.1 - 4.1e-07 29.8 0.6 0.073 13.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat DUF4131 PF13567.6 RJW67449.1 - 0.065 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 RJW67449.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.8 RJW67449.1 - 0.46 10.4 6.5 0.12 12.2 3.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Neur_chan_LBD PF02931.23 RJW67451.1 - 2.7e-51 174.1 3.2 3.9e-51 173.6 3.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW67451.1 - 2.7e-21 76.8 1.8 6.4e-21 75.5 1.8 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region HypA PF01155.19 RJW67451.1 - 0.03 14.3 0.2 5.5 7.1 0.1 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mic1 PF07035.12 RJW67452.1 - 6.7e-41 139.6 5.4 1.4e-40 138.5 5.4 1.5 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like RVT_1 PF00078.27 RJW67453.1 - 9.9e-05 21.9 0.0 0.00016 21.2 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Anp1 PF03452.14 RJW67455.1 - 5.9e-08 32.4 0.3 0.32 10.4 0.0 4.8 5 1 0 6 6 6 3 Anp1 2OG-FeII_Oxy PF03171.20 RJW67455.1 - 1.6e-05 25.3 0.0 0.0014 19.0 0.0 2.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 RJW67455.1 - 2.2e-05 25.2 0.1 0.00043 21.1 0.1 2.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF3148 PF11347.8 RJW67455.1 - 0.0042 16.8 0.3 2.8 7.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3148) KH_1 PF00013.29 RJW67457.1 - 0.0097 15.7 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 KH domain EAF PF09816.9 RJW67458.1 - 4.5e-20 71.9 0.0 6.5e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor ABC_membrane PF00664.23 RJW67461.1 - 2.8e-57 194.4 19.0 3.7e-31 108.8 8.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RJW67461.1 - 5.4e-53 179.2 0.0 1.3e-28 100.2 0.0 3.2 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 RJW67461.1 - 1.7e-10 40.7 0.7 0.00018 21.0 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RJW67461.1 - 4.6e-05 23.1 0.2 0.49 10.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RJW67461.1 - 6.2e-05 23.1 3.4 0.83 9.8 0.0 4.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RJW67461.1 - 0.00011 22.1 3.1 2.1 8.1 0.1 4.4 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RJW67461.1 - 0.00012 22.0 0.1 0.019 14.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 RJW67461.1 - 0.00037 21.0 0.1 0.3 11.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 RJW67461.1 - 0.00053 19.2 0.0 0.96 8.6 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_16 PF13191.6 RJW67461.1 - 0.00054 20.4 0.0 1.6 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 RJW67461.1 - 0.03 14.6 0.2 7.7 6.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 RJW67461.1 - 0.046 13.4 0.0 0.56 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.12 RJW67461.1 - 0.052 13.5 1.0 12 5.8 0.1 2.9 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 RJW67461.1 - 0.062 13.0 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 RJW67461.1 - 0.063 12.9 0.0 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 RJW67461.1 - 0.067 12.2 0.0 2.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 RJW67461.1 - 0.085 11.8 0.8 2.7 6.8 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 RJW67461.1 - 0.12 12.4 3.7 0.16 12.1 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_7 PF12775.7 RJW67461.1 - 0.17 11.4 0.1 10 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4191 PF13829.6 RJW67461.1 - 0.4 10.0 4.4 0.072 12.4 0.4 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4191) Dynamin_N PF00350.23 RJW67461.1 - 2.2 8.3 4.8 1.3 9.1 0.2 2.7 2 0 0 2 2 2 0 Dynamin family Neur_chan_LBD PF02931.23 RJW67463.1 - 6.1e-49 166.4 2.9 8.6e-49 165.9 2.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW67463.1 - 7.1e-24 85.2 2.4 1.1e-23 84.5 0.2 2.1 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Enkurin PF13864.6 RJW67464.1 - 3.2e-25 88.4 1.9 3.2e-25 88.4 1.9 1.7 2 0 0 2 2 2 1 Calmodulin-binding 7TMR-HDED PF07697.11 RJW67464.1 - 0.095 12.8 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 7TM-HD extracellular RRM_1 PF00076.22 RJW67467.1 - 8.1e-18 64.0 0.0 1.3e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_A17 PF05380.13 RJW67468.1 - 6.3e-26 91.3 0.0 2.3e-25 89.5 0.0 1.9 2 0 0 2 2 2 1 Pao retrotransposon peptidase DUF1987 PF09345.10 RJW67468.1 - 0.02 14.6 1.0 6.3 6.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) RE_HindVP PF09519.10 RJW67468.1 - 0.023 13.8 0.6 2.5 7.0 0.1 2.1 2 0 0 2 2 2 0 HindVP restriction endonuclease T4_deiodinase PF00837.17 RJW67468.1 - 0.088 12.1 0.2 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Iodothyronine deiodinase eIF3g PF12353.8 RJW67468.1 - 0.29 11.5 1.2 0.66 10.4 0.1 2.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Surp PF01805.20 RJW67469.1 - 2.1e-44 149.3 6.0 3.1e-23 81.5 0.3 2.5 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 RJW67469.1 - 1.1e-42 146.4 0.5 9.5e-41 140.0 0.5 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein SMC_ScpA PF02616.14 RJW67469.1 - 0.11 12.3 0.6 0.23 11.4 0.6 1.4 1 0 0 1 1 1 0 Segregation and condensation protein ScpA NYD-SP28_assoc PF14775.6 RJW67470.1 - 0.0097 16.0 5.1 0.23 11.6 0.4 3.5 2 0 0 2 2 2 1 Sperm tail C-terminal domain BicD PF09730.9 RJW67470.1 - 0.022 13.2 18.9 0.042 12.3 19.0 1.5 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D KASH_CCD PF14662.6 RJW67470.1 - 0.23 11.2 37.5 0.018 14.8 25.0 3.5 4 0 0 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF641 PF04859.12 RJW67470.1 - 2.2 8.6 12.4 12 6.2 3.8 3.5 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DivIC PF04977.15 RJW67470.1 - 2.8 7.8 12.1 2.9 7.7 1.0 3.5 2 1 0 3 3 3 0 Septum formation initiator SRA1 PF07304.11 RJW67472.1 - 0.15 11.9 1.1 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) zf-C2H2_4 PF13894.6 RJW67472.1 - 1 10.4 28.9 0.64 11.0 7.7 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger KH_1 PF00013.29 RJW67473.1 - 1.9e-07 30.8 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 KH domain EIF_2_alpha PF07541.12 RJW67473.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Cofilin_ADF PF00241.20 RJW67474.1 - 9.7e-33 112.6 0.1 1.4e-32 112.0 0.1 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PP2C PF00481.21 RJW67476.1 - 6.4e-53 180.0 0.0 4.3e-52 177.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RJW67476.1 - 1.9e-05 24.4 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Peptidase_S26 PF10502.9 RJW67476.1 - 0.049 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 Spectrin PF00435.21 RJW67478.1 - 0 1264.5 229.8 1.3e-27 96.3 0.9 22.4 23 0 0 23 23 22 21 Spectrin repeat EFhand_Ca_insen PF08726.10 RJW67478.1 - 4.8e-22 77.8 5.2 1.4e-20 73.1 2.9 4.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand SH3_1 PF00018.28 RJW67478.1 - 3.4e-14 52.2 1.2 5.5e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 SH3 domain EF-hand_1 PF00036.32 RJW67478.1 - 1.9e-13 48.9 4.6 1.9e-06 27.0 0.2 4.0 4 0 0 4 4 4 2 EF hand SH3_9 PF14604.6 RJW67478.1 - 3.3e-11 42.9 0.0 9.1e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_7 PF13499.6 RJW67478.1 - 6.8e-10 39.3 1.3 6.8e-10 39.3 1.3 4.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW67478.1 - 9.9e-10 37.6 4.5 3.4e-05 23.4 0.2 4.8 4 0 0 4 4 3 2 EF-hand domain EF-hand_8 PF13833.6 RJW67478.1 - 8.6e-09 35.1 0.5 0.009 15.8 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW67478.1 - 3.6e-08 32.5 0.7 0.027 14.0 0.0 4.4 4 0 0 4 4 4 2 EF hand SH3_2 PF07653.17 RJW67478.1 - 2.6e-05 23.8 0.0 6.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 RJW67478.1 - 0.012 15.7 1.7 0.071 13.2 0.0 3.1 2 1 0 2 2 2 0 SH3 domain zf-MIZ PF02891.20 RJW67478.1 - 0.023 14.4 3.4 0.39 10.5 0.1 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger INCENP_N PF12178.8 RJW67478.1 - 2 8.5 7.0 0.56 10.2 0.1 4.0 4 0 0 4 4 3 0 Chromosome passenger complex (CPC) protein INCENP N terminal GvpG PF05120.12 RJW67478.1 - 7.5 6.6 11.8 5.4 7.1 0.0 5.6 4 0 0 4 4 4 0 Gas vesicle protein G Collagen PF01391.18 RJW67480.1 - 3.4e-62 206.1 229.2 4e-09 36.1 28.3 9.0 1 1 5 6 6 6 5 Collagen triple helix repeat (20 copies) C4 PF01413.19 RJW67480.1 - 6.3e-62 206.8 2.2 7.6e-34 116.4 0.8 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Alpha_TIF PF02232.15 RJW67481.1 - 0.024 13.8 0.0 0.025 13.7 0.0 1.0 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) Collagen PF01391.18 RJW67482.1 - 9.6e-191 617.8 767.8 5.6e-10 38.8 23.2 30.1 5 4 19 24 24 24 21 Collagen triple helix repeat (20 copies) C4 PF01413.19 RJW67482.1 - 6.2e-63 210.1 2.7 4.3e-34 117.2 1.2 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen OTU PF02338.19 RJW67484.1 - 2.7e-17 63.5 0.2 1.2e-16 61.3 0.1 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RJW67484.1 - 0.00049 19.6 0.5 0.24 10.8 0.4 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain RAP PF08373.10 RJW67484.1 - 0.023 14.8 0.9 7.7 6.7 0.0 2.8 3 0 0 3 3 3 0 RAP domain Lung_7-TM_R PF06814.13 RJW67485.1 - 6.6e-71 239.0 17.5 8.2e-71 238.6 17.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 RJW67485.1 - 5.7e-09 35.8 17.6 1e-08 35.0 17.6 1.5 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain zf-met PF12874.7 RJW67486.1 - 8.6e-11 41.9 3.5 0.0043 17.4 0.6 3.8 4 0 0 4 4 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW67486.1 - 5.6e-08 32.9 7.1 0.092 13.1 0.1 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 RJW67486.1 - 5e-07 29.4 0.5 0.0036 17.0 1.0 2.6 2 0 0 2 2 2 2 U1 zinc finger zf-C2H2_2 PF12756.7 RJW67486.1 - 5.5e-07 29.8 9.2 0.22 11.9 1.5 4.3 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 RJW67486.1 - 7.2e-07 29.9 0.1 1.9e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats Yippee-Mis18 PF03226.14 RJW67486.1 - 9.4e-05 22.6 0.4 0.17 12.1 0.0 3.3 3 0 0 3 3 3 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_4 PF13894.6 RJW67486.1 - 0.00026 21.6 6.7 0.14 13.1 0.1 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW67486.1 - 0.0005 20.4 6.5 0.12 12.9 0.4 4.4 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-DBF PF07535.12 RJW67486.1 - 0.002 18.2 14.9 3.3 7.9 0.2 4.6 4 0 0 4 4 4 2 DBF zinc finger GFA PF04828.14 RJW67486.1 - 0.0058 16.9 1.7 0.52 10.7 0.0 3.0 3 1 0 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme RIG-I_C-RD PF11648.8 RJW67486.1 - 0.01 16.0 0.5 0.067 13.4 0.0 2.4 3 0 0 3 3 3 0 C-terminal domain of RIG-I DUF629 PF04780.12 RJW67486.1 - 0.07 11.6 0.7 2.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) AKAP95 PF04988.12 RJW67486.1 - 0.1 12.8 3.9 4.5 7.5 0.0 2.7 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_8 PF15909.5 RJW67486.1 - 0.13 12.6 3.1 0.3 11.4 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc ribbon DZR PF12773.7 RJW67486.1 - 0.26 11.3 13.3 2.9 8.0 0.0 4.1 3 1 0 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 RJW67486.1 - 1.4 8.9 10.3 1.6 8.8 0.5 4.0 4 0 0 4 4 4 0 zinc-ribbons zf-CRD PF17979.1 RJW67486.1 - 9.8 6.3 12.1 1.5 8.9 1.3 3.3 3 2 1 4 4 4 0 Cysteine rich domain with multizinc binding regions RRM_1 PF00076.22 RJW67487.1 - 2.3e-33 113.8 0.2 9.4e-16 57.4 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW67487.1 - 5.1e-11 42.6 0.1 2.3e-06 27.7 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RL PF17797.1 RJW67487.1 - 0.013 15.4 0.0 8.2 6.5 0.0 2.6 2 0 0 2 2 2 0 RL domain NTase_sub_bind PF08780.11 RJW67487.1 - 0.082 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like TPR_2 PF07719.17 RJW67488.1 - 1.8e-21 74.4 28.5 0.00038 20.4 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 RJW67488.1 - 6.2e-16 58.5 25.4 4.1e-07 30.2 4.9 6.2 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 RJW67488.1 - 7.2e-15 54.1 25.3 0.0016 18.2 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 RJW67488.1 - 4.8e-10 38.8 16.9 0.029 14.6 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 RJW67488.1 - 1.8e-09 38.1 13.8 0.00047 20.7 0.0 6.2 4 2 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 RJW67488.1 - 1.7e-06 27.6 9.5 0.14 11.9 0.0 5.8 6 1 1 7 7 7 3 TPR repeat TPR_MalT PF17874.1 RJW67488.1 - 2.9e-06 26.9 10.5 0.00061 19.3 7.9 3.3 2 2 1 3 3 3 1 MalT-like TPR region TPR_19 PF14559.6 RJW67488.1 - 2e-05 25.0 14.3 0.047 14.2 0.0 5.6 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 RJW67488.1 - 2e-05 24.3 12.7 0.54 10.4 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW67488.1 - 0.0002 21.5 3.2 0.22 12.0 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW67488.1 - 0.00024 21.2 6.2 0.0043 17.2 0.0 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 RJW67488.1 - 0.0031 17.3 2.9 0.0056 16.4 0.4 2.7 2 2 1 3 3 3 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 RJW67488.1 - 0.0053 17.5 13.1 0.11 13.4 0.0 6.4 4 2 4 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 RJW67488.1 - 0.0063 17.1 13.8 45 5.0 0.0 7.9 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW67488.1 - 0.01 16.0 21.3 0.014 15.6 0.2 5.7 3 2 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TIR PF01582.20 RJW67488.1 - 0.031 14.1 2.4 0.066 13.0 2.4 1.6 1 0 0 1 1 1 0 TIR domain TPR_21 PF09976.9 RJW67488.1 - 0.22 11.2 11.6 0.28 10.9 2.6 3.8 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 RJW67488.1 - 2.3 8.2 20.7 17 5.4 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat DNApol_Exo PF18136.1 RJW67490.1 - 9.3e-92 307.1 0.0 1.6e-91 306.4 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 RJW67490.1 - 4e-43 147.9 0.0 6.4e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 RJW67490.1 - 0.04 13.6 0.0 0.14 11.9 0.0 2.0 1 1 0 1 1 1 0 3'-5' exonuclease Glyco_transf_8 PF01501.20 RJW67491.1 - 1.6e-22 80.3 0.1 4.8e-20 72.2 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 RJW67491.1 - 0.045 13.1 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative PHD PF00628.29 RJW67492.1 - 6.3e-06 26.0 8.6 1.6e-05 24.7 8.6 1.8 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 RJW67492.1 - 0.015 15.5 2.0 0.047 14.0 2.0 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain ING PF12998.7 RJW67492.1 - 0.075 13.6 4.6 0.3 11.7 4.6 2.0 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Peptidase_M16_C PF05193.21 RJW67492.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain zf-RING_2 PF13639.6 RJW67492.1 - 0.53 10.7 7.9 1.4 9.4 7.9 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING-like PF08746.11 RJW67492.1 - 3.3 8.1 6.7 6.6 7.1 6.7 1.6 1 0 0 1 1 1 0 RING-like domain Spy1 PF11357.8 RJW67493.1 - 3.1e-22 79.2 1.2 4.3e-22 78.8 1.2 1.2 1 0 0 1 1 1 1 Cell cycle regulatory protein Rootletin PF15035.6 RJW67494.1 - 9.4e-53 179.0 24.9 9.4e-53 179.0 24.9 9.0 3 2 4 7 7 7 1 Ciliary rootlet component, centrosome cohesion DUF4201 PF13870.6 RJW67494.1 - 0.00018 21.3 7.1 0.00018 21.3 7.1 11.1 5 2 7 12 12 12 4 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 RJW67494.1 - 0.0017 18.4 16.4 0.0017 18.4 16.4 10.5 3 2 8 11 11 11 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YtxH PF12732.7 RJW67494.1 - 4.6 7.9 0.0 4.6 7.9 0.0 8.3 6 2 2 8 8 8 0 YtxH-like protein Collagen PF01391.18 RJW67495.1 - 9.3e-144 467.3 560.8 1.1e-09 37.9 29.7 20.5 7 6 11 18 18 18 17 Collagen triple helix repeat (20 copies) Med26 PF08711.11 RJW67496.1 - 1.1e-12 47.7 0.0 2.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SASP_gamma PF04259.14 RJW67496.1 - 0.046 14.2 1.7 2.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Small, acid-soluble spore protein, gamma-type Herpes_US9 PF06072.11 RJW67496.1 - 5.8 6.9 5.6 1.1 9.2 1.6 1.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 zf-CCCH PF00642.24 RJW67497.1 - 3.9e-05 23.5 7.1 6.6e-05 22.7 7.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 RJW67497.1 - 0.00039 20.2 0.0 0.0074 16.1 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 RJW67497.1 - 0.052 13.6 5.5 0.09 12.9 5.5 1.4 1 0 0 1 1 1 0 Zinc finger domain LUC7 PF03194.15 RJW67497.1 - 0.06 13.0 3.1 0.12 12.1 3.1 1.5 1 0 0 1 1 1 0 LUC7 N_terminus zf-CCCH_2 PF14608.6 RJW67497.1 - 1 10.0 7.0 1.8 9.1 7.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Ank_2 PF12796.7 RJW67498.1 - 4e-22 78.6 0.2 2.2e-13 50.6 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW67498.1 - 6.2e-18 64.9 2.4 1.8e-10 41.1 0.1 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW67498.1 - 3.6e-17 60.7 3.3 0.00013 22.2 0.0 5.5 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RJW67498.1 - 2.2e-14 53.3 0.7 5.3e-08 33.0 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RJW67498.1 - 1.2e-11 44.5 4.8 0.0061 17.0 0.2 4.9 5 1 1 6 6 6 3 Ankyrin repeat Collagen PF01391.18 RJW67499.1 - 4.1e-202 654.2 798.0 3.4e-09 36.3 25.7 30.6 6 5 20 27 27 27 25 Collagen triple helix repeat (20 copies) C4 PF01413.19 RJW67499.1 - 2.3e-43 147.1 4.1 2.6e-35 121.2 1.7 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen OppC_N PF12911.7 RJW67499.1 - 0.3 11.1 0.3 0.5 10.4 0.3 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Cir_N PF10197.9 RJW67500.1 - 1.2e-11 44.6 5.7 1.2e-11 44.6 5.7 2.4 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 RJW67500.1 - 0.0011 18.7 0.1 0.0027 17.5 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle G-alpha PF00503.20 RJW67503.1 - 1.5e-89 300.6 0.1 1.7e-89 300.4 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RJW67503.1 - 7e-10 38.6 0.1 1.6e-09 37.4 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW67503.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Sugar_tr PF00083.24 RJW67504.1 - 1.6e-25 89.9 16.2 4e-25 88.6 16.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW67504.1 - 2.3e-19 69.5 29.1 2.3e-17 63.0 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Viral_cys_rich PF08008.12 RJW67504.1 - 0.018 15.1 0.1 0.035 14.1 0.1 1.5 1 0 0 1 1 1 0 Viral cysteine rich Na_H_Exchanger PF00999.21 RJW67505.1 - 2.5e-36 125.3 47.9 3.4e-36 124.8 47.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Diphthamide_syn PF01866.17 RJW67506.1 - 1.5e-59 202.0 0.0 3e-59 200.9 0.0 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Tmp39 PF10271.9 RJW67507.1 - 3.5e-05 23.0 5.2 4.1e-05 22.8 5.2 1.0 1 0 0 1 1 1 1 Putative transmembrane protein SWIB PF02201.18 RJW67508.1 - 9.7e-22 76.7 0.0 2.4e-21 75.4 0.0 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 RJW67508.1 - 3e-16 59.1 0.5 4.8e-16 58.4 0.5 1.3 1 0 0 1 1 1 1 DEK C terminal domain RPN2_C PF18004.1 RJW67508.1 - 0.035 14.0 3.1 0.054 13.4 3.1 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain eIF-3c_N PF05470.12 RJW67508.1 - 0.039 12.3 1.9 0.043 12.1 1.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CCDC106 PF15794.5 RJW67508.1 - 0.52 10.0 9.6 0.83 9.3 9.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 RJW67508.1 - 2.9 6.6 4.0 3.3 6.4 4.0 1.1 1 0 0 1 1 1 0 Presenilin CENP-F_leu_zip PF10473.9 RJW67510.1 - 0.43 10.6 36.4 0.3 11.1 14.9 3.8 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 RJW67510.1 - 2.6 8.1 13.8 1.8 8.6 2.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Tmp39 PF10271.9 RJW67512.1 - 7.1e-48 163.7 10.3 1.1e-47 163.0 10.3 1.3 1 0 0 1 1 1 1 Putative transmembrane protein UCH PF00443.29 RJW67513.1 - 1.4e-26 93.6 0.0 2.6e-26 92.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW67513.1 - 0.0021 17.7 0.0 0.0092 15.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.22 RJW67514.1 - 9.7e-09 34.9 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BCHF PF07284.11 RJW67515.1 - 0.16 12.0 2.5 0.12 12.4 0.5 1.9 1 1 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DUF2070 PF09843.9 RJW67515.1 - 0.99 7.6 10.8 1.2 7.3 10.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TrbL PF04610.14 RJW67515.1 - 5.5 6.7 20.8 0.19 11.5 10.5 2.2 2 1 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein DUF2721 PF11026.8 RJW67516.1 - 0.017 15.0 8.6 0.017 15.0 8.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) 7TM_GPCR_Srh PF10318.9 RJW67516.1 - 0.19 10.8 7.3 0.49 9.4 7.3 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Amastin PF07344.11 RJW67516.1 - 0.65 9.8 11.4 0.32 10.8 9.2 1.7 1 1 0 1 1 1 0 Amastin surface glycoprotein ABC2_membrane_3 PF12698.7 RJW67516.1 - 5.7 5.9 12.6 7.8 5.5 12.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SUR7 PF06687.12 RJW67516.1 - 5.8 6.5 17.0 15 5.1 17.0 1.7 1 1 0 1 1 1 0 SUR7/PalI family RNA_pol_Rpb6 PF01192.22 RJW67517.1 - 0.024 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb6 DUF4796 PF16044.5 RJW67520.1 - 1.8e-06 27.7 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4796) Ank_2 PF12796.7 RJW67521.1 - 0.0089 16.6 0.4 0.021 15.4 0.2 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW67521.1 - 0.016 15.5 0.1 0.047 14.0 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 RJW67521.1 - 0.13 12.8 1.4 17 6.0 0.0 2.7 2 1 1 3 3 3 0 Ankyrin repeat RRM_1 PF00076.22 RJW67526.1 - 4.3e-91 298.8 0.5 2.3e-22 78.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 RJW67526.1 - 1.3e-23 83.0 0.5 1.6e-22 79.4 0.4 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 RJW67526.1 - 8.4e-09 35.3 0.3 0.03 14.3 0.0 4.2 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 RJW67526.1 - 2.5e-07 30.7 1.7 1.4 9.0 0.0 4.8 5 0 0 5 5 5 2 RNA binding motif RRM_occluded PF16842.5 RJW67526.1 - 4.2e-06 26.5 0.0 0.3 11.0 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif SET_assoc PF11767.8 RJW67526.1 - 9.4e-06 25.2 1.7 2.7 7.7 0.0 4.7 5 0 0 5 5 5 2 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 RJW67526.1 - 8.1e-05 22.7 0.1 2.5 8.3 0.0 4.3 4 1 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 RJW67526.1 - 0.0001 22.3 0.1 20 5.3 0.0 4.4 4 0 0 4 4 4 0 Limkain b1 OB_RNB PF08206.11 RJW67526.1 - 0.021 14.5 2.4 8.3 6.2 0.0 4.1 4 0 0 4 4 4 0 Ribonuclease B OB domain CHASE8 PF17152.4 RJW67526.1 - 0.28 11.4 1.1 5.6 7.3 0.2 2.9 3 0 0 3 3 3 0 Periplasmic sensor domain Glyco_hydro_85 PF03644.13 RJW67527.1 - 1.1e-70 238.4 0.0 1.5e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 RVT_1 PF00078.27 RJW67527.1 - 1.6e-09 37.6 0.0 2.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TGF_beta PF00019.20 RJW67529.1 - 5.9e-30 104.3 0.3 1.4e-29 103.1 0.3 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain NAPRTase PF04095.16 RJW67530.1 - 3e-62 210.4 0.0 4e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 RJW67530.1 - 4.3e-36 123.3 0.4 1.3e-34 118.5 0.4 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5598) Prenylcys_lyase PF07156.14 RJW67531.1 - 5.3e-73 246.2 0.0 7e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 RJW67531.1 - 5.7e-18 65.4 0.2 5.2e-17 62.3 0.2 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RJW67531.1 - 5.5e-16 58.6 0.2 1.1e-15 57.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RJW67531.1 - 6.7e-05 22.6 0.0 0.00022 20.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RJW67531.1 - 8.5e-05 21.9 0.1 0.0011 18.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RJW67531.1 - 0.0026 16.7 0.3 0.0039 16.1 0.3 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 RJW67531.1 - 0.013 15.5 0.2 0.084 12.9 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 RJW67531.1 - 0.047 14.3 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RJW67531.1 - 0.053 12.8 0.1 0.09 12.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family zf-H2C2_2 PF13465.6 RJW67533.1 - 4.9e-16 58.3 21.1 7.7e-08 32.4 1.6 5.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 RJW67533.1 - 4.2e-15 55.3 29.3 2.7e-06 27.5 2.6 4.9 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW67533.1 - 4.4e-09 36.4 25.3 0.0017 19.1 1.5 4.6 4 0 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RJW67533.1 - 7.8e-06 25.5 25.7 0.00026 20.7 1.2 5.0 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RJW67533.1 - 2.4e-05 24.5 8.2 0.054 13.8 0.3 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 RJW67533.1 - 0.0048 16.9 13.2 0.086 12.9 0.8 3.4 2 1 1 3 3 3 2 BED zinc finger zf-C2H2_11 PF16622.5 RJW67533.1 - 0.0071 16.1 1.1 0.0071 16.1 1.1 4.5 5 0 0 5 5 5 1 zinc-finger C2H2-type zf-C2HE PF16278.5 RJW67533.1 - 0.0092 16.4 10.1 0.31 11.5 0.2 3.6 1 1 2 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 RJW67533.1 - 0.01 15.7 0.2 0.46 10.4 0.0 2.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.6 RJW67533.1 - 0.017 15.1 0.8 0.017 15.1 0.8 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Spt46 PF17734.1 RJW67533.1 - 0.33 10.7 6.6 1.9 8.3 1.2 2.8 1 1 1 3 3 3 0 Spermatogenesis-associated protein 46 GAGA PF09237.11 RJW67533.1 - 0.33 10.8 9.3 0.64 9.9 0.3 3.1 1 1 2 3 3 3 0 GAGA factor zf-C2H2_3rep PF18868.1 RJW67533.1 - 0.36 11.5 6.3 10 6.8 0.2 3.7 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn_ribbon_SprT PF17283.2 RJW67533.1 - 0.88 9.5 9.0 3.6 7.6 0.7 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-MYST PF17772.1 RJW67533.1 - 2.1 8.0 7.9 3.7 7.2 0.2 3.4 3 1 1 4 4 4 0 MYST family zinc finger domain Ribosomal_L17 PF01196.19 RJW67534.1 - 4.2e-09 37.2 0.0 9e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 rve PF00665.26 RJW67538.1 - 3.2e-14 53.1 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RJW67538.1 - 0.023 14.5 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Innexin PF00876.18 RJW67540.1 - 4.3e-42 144.7 2.6 5.8e-42 144.2 2.6 1.2 1 0 0 1 1 1 1 Innexin DUF2398 PF09661.10 RJW67541.1 - 0.21 10.8 0.1 0.29 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) CENP-B_dimeris PF09026.10 RJW67541.1 - 1 9.8 5.6 2.9 8.3 5.4 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ig_3 PF13927.6 RJW67542.1 - 2e-40 137.3 13.0 4.2e-10 40.1 0.1 8.8 8 1 0 8 8 8 6 Immunoglobulin domain I-set PF07679.16 RJW67542.1 - 2.1e-29 101.4 0.3 3.7e-07 30.1 0.0 7.7 6 2 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW67542.1 - 2.9e-23 82.0 8.2 7.9e-05 22.9 0.0 9.9 8 2 1 9 9 9 5 Immunoglobulin domain ig PF00047.25 RJW67542.1 - 9.1e-23 80.2 4.1 2.9e-05 24.1 0.1 7.8 8 1 0 8 8 7 5 Immunoglobulin domain V-set PF07686.17 RJW67542.1 - 2.1e-18 66.4 9.7 0.18 12.0 0.0 10.5 8 5 1 9 9 9 6 Immunoglobulin V-set domain Ldl_recept_a PF00057.18 RJW67542.1 - 3.6e-17 62.3 42.9 3.5e-06 27.1 7.9 4.6 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Laminin_B PF00052.18 RJW67542.1 - 3.8e-12 46.3 0.0 3.1e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 Laminin B (Domain IV) Laminin_EGF PF00053.24 RJW67542.1 - 0.00036 20.6 16.4 0.00036 20.6 16.4 7.5 8 1 1 9 9 6 3 Laminin EGF domain Adeno_E3_CR1 PF02440.15 RJW67542.1 - 0.007 16.1 0.0 6.7 6.6 0.0 3.5 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 V-set_CD47 PF08204.11 RJW67542.1 - 0.0076 16.2 0.0 4.5 7.3 0.0 3.6 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain C2-set_2 PF08205.12 RJW67542.1 - 0.1 12.7 4.8 0.51 10.4 0.0 3.8 4 0 0 4 4 4 0 CD80-like C2-set immunoglobulin domain Abhydrolase_1 PF00561.20 RJW67543.1 - 2.4e-08 34.0 0.0 5.6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RJW67543.1 - 3e-06 26.7 0.0 1.2e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RJW67543.1 - 0.015 15.9 0.1 0.04 14.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RJW67543.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family LRR_8 PF13855.6 RJW67545.1 - 3.2e-16 58.9 12.4 1.2e-09 37.8 4.6 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RJW67545.1 - 8.4e-11 41.9 11.2 4.2e-05 23.8 2.5 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 RJW67545.1 - 6.3e-08 33.1 1.0 2.9e-07 31.0 1.0 2.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RJW67545.1 - 1.1e-07 31.8 0.2 2.2e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 RJW67545.1 - 2.6e-06 27.5 1.2 8.1e-06 25.9 1.2 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 RJW67545.1 - 0.00016 21.7 11.1 1.5 9.7 1.2 5.9 5 0 0 5 5 4 2 Leucine Rich Repeat Ig_2 PF13895.6 RJW67545.1 - 0.0002 21.7 0.4 0.0007 19.9 0.4 2.0 1 0 0 1 1 1 1 Immunoglobulin domain C1-set PF07654.15 RJW67545.1 - 0.0012 19.2 0.7 0.0043 17.4 0.7 2.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain V-set PF07686.17 RJW67545.1 - 0.023 14.9 0.4 0.062 13.5 0.4 1.7 1 0 0 1 1 1 0 Immunoglobulin V-set domain LRR_5 PF13306.6 RJW67545.1 - 0.027 14.4 0.0 0.16 12.0 0.0 2.1 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RJW67545.1 - 0.046 13.2 1.1 0.17 11.4 1.1 1.8 2 0 0 2 2 2 0 Leucine-rich repeat Orthoreo_P10 PF07204.11 RJW67545.1 - 0.068 13.1 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TPKR_C2 PF16920.5 RJW67545.1 - 0.22 11.7 1.1 0.72 10.0 1.1 1.9 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 RJW67545.1 - 1.9 8.8 7.3 80 3.7 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat HTHP PF11534.8 RJW67546.1 - 0.066 13.6 1.9 0.083 13.3 0.3 2.0 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) Ank_2 PF12796.7 RJW67549.1 - 3.3e-28 98.1 5.3 5.4e-13 49.3 0.8 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW67549.1 - 4.2e-23 81.4 6.9 4e-08 33.6 0.7 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW67549.1 - 4.1e-21 72.8 9.2 0.00011 22.4 0.4 6.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 RJW67549.1 - 4.8e-21 74.5 21.6 2.9e-06 27.4 1.7 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RJW67549.1 - 3.6e-17 62.0 19.3 0.00017 21.8 0.2 5.6 5 0 0 5 5 5 5 Ankyrin repeat SOCS_box PF07525.16 RJW67549.1 - 1.4e-05 25.3 0.1 2.7e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 SOCS box Glyco_transf_8 PF01501.20 RJW67551.1 - 4.3e-09 36.3 0.0 9.6e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 RJW67551.1 - 0.0029 17.1 0.1 0.0052 16.2 0.1 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 KH_1 PF00013.29 RJW67552.1 - 2.2e-06 27.4 0.0 0.022 14.6 0.0 2.6 2 0 0 2 2 2 2 KH domain Agenet PF05641.12 RJW67552.1 - 0.049 14.1 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Agenet domain FliT PF05400.13 RJW67552.1 - 0.11 13.3 2.7 0.48 11.3 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein FliT FXMRP1_C_core PF12235.8 RJW67552.1 - 3.9 8.1 14.8 3e+02 2.0 14.6 2.8 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal ThiF PF00899.21 RJW67556.1 - 4.6e-46 157.2 0.0 6.4e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 RJW67556.1 - 0.00079 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 RJW67556.1 - 0.0047 16.3 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RJW67556.1 - 0.042 14.1 0.9 0.49 10.6 0.9 2.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 RJW67556.1 - 0.066 13.6 0.0 0.22 12.0 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF1664 PF07889.12 RJW67556.1 - 0.14 12.2 0.5 0.3 11.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RT_RNaseH_2 PF17919.1 RJW67559.1 - 1.9e-38 130.5 0.0 3.7e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW67559.1 - 6.3e-35 119.6 0.0 1.3e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW67559.1 - 9.3e-24 84.2 0.0 1.6e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RJW67559.1 - 2.5e-22 79.3 0.0 5.8e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW67559.1 - 9.8e-18 64.0 0.3 9.8e-18 64.0 0.3 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RJW67559.1 - 1.1e-05 25.6 0.1 1.1e-05 25.6 0.1 1.9 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 RJW67559.1 - 5.8e-05 22.8 0.0 0.00021 21.0 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 RJW67559.1 - 0.011 16.2 0.0 0.025 15.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SRPRB PF09439.10 RJW67560.1 - 2e-42 144.7 0.3 2.5e-42 144.3 0.3 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 RJW67560.1 - 1.6e-15 57.0 0.1 2.1e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW67560.1 - 1.3e-06 28.5 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RJW67560.1 - 1.3e-05 24.8 1.1 0.034 13.7 0.3 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RJW67560.1 - 5.7e-05 22.7 0.1 9.1e-05 22.0 0.1 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 RJW67560.1 - 0.012 14.8 0.2 0.022 13.9 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit Roc PF08477.13 RJW67560.1 - 0.021 15.0 0.0 0.049 13.8 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 RJW67561.1 - 7.7e-48 163.1 0.0 1.1e-47 162.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67561.1 - 1.6e-18 67.0 0.0 2.4e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW67561.1 - 0.0046 15.8 0.0 0.0097 14.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Anticodon_1 PF08264.13 RJW67562.1 - 1.9e-15 57.2 0.1 2.8e-14 53.4 0.1 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA EutK_C PF16365.5 RJW67563.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus DUF2760 PF10816.8 RJW67564.1 - 0.016 15.1 5.1 0.089 12.6 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2760) BTB_2 PF02214.22 RJW67567.1 - 1.1e-18 67.4 0.0 2.2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 RJW67567.1 - 1e-05 25.7 0.0 2.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 RJW67567.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_M13_N PF05649.13 RJW67569.1 - 5.8e-08 32.8 0.1 1.1e-07 31.9 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M13 DUF5345 PF17280.2 RJW67569.1 - 0.36 10.8 1.9 0.91 9.5 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Band_7 PF01145.25 RJW67570.1 - 5.3e-24 85.2 2.3 8.2e-24 84.6 2.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family FHA PF00498.26 RJW67571.1 - 3.8e-13 49.6 0.4 1e-12 48.2 0.4 1.8 1 0 0 1 1 1 1 FHA domain WEMBL PF05701.11 RJW67571.1 - 0.00065 18.5 16.8 0.00065 18.5 16.8 1.9 3 0 0 3 3 3 1 Weak chloroplast movement under blue light TMF_DNA_bd PF12329.8 RJW67571.1 - 2 8.5 41.0 0.78 9.8 6.5 5.8 3 2 3 6 6 6 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 RJW67571.1 - 2.9 8.3 37.5 0.41 11.1 20.6 3.2 2 1 1 3 3 3 0 Fez1 FtsX PF02687.21 RJW67572.1 - 0.14 12.7 0.2 0.14 12.7 0.2 2.2 2 0 0 2 2 2 0 FtsX-like permease family SLATT_1 PF18181.1 RJW67572.1 - 1.5 8.8 5.2 3.5 7.6 5.1 1.6 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Enolase_C PF00113.22 RJW67573.1 - 2.5e-153 509.5 0.1 3.4e-153 509.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 RJW67573.1 - 9.4e-59 197.3 0.1 1.5e-58 196.6 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 RJW67573.1 - 3.3e-08 33.4 0.0 5.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 RJW67573.1 - 0.00045 19.4 1.2 0.00096 18.4 0.2 1.9 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus 5_nucleotid PF05761.14 RJW67574.1 - 7.5e-168 559.2 0.1 9.2e-168 558.9 0.1 1.1 1 0 0 1 1 1 1 5' nucleotidase family Cadherin PF00028.17 RJW67575.1 - 7.8e-65 215.4 13.7 6.8e-17 61.7 0.1 8.9 8 1 1 9 9 9 7 Cadherin domain Cadherin_3 PF16184.5 RJW67575.1 - 3.7e-07 30.1 17.0 0.00043 20.3 0.1 5.4 6 0 0 6 6 6 3 Cadherin-like Cadherin_2 PF08266.12 RJW67575.1 - 4.8e-05 23.1 0.2 0.37 10.7 0.1 4.8 4 1 0 4 4 4 1 Cadherin-like Cadherin_pro PF08758.11 RJW67575.1 - 0.00017 21.7 0.3 0.00094 19.3 0.0 2.4 3 0 0 3 3 3 1 Cadherin prodomain like Herpes_gE PF02480.16 RJW67575.1 - 0.013 14.2 0.0 0.03 13.1 0.0 1.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF3694 PF12473.8 RJW67575.1 - 0.014 16.0 0.1 0.072 13.7 0.0 2.3 2 0 0 2 2 2 0 Kinesin protein Cadherin_4 PF17803.1 RJW67575.1 - 0.1 13.3 10.9 0.59 10.8 0.4 4.2 4 0 0 4 4 4 0 Bacterial cadherin-like domain DUF4625 PF15418.6 RJW67575.1 - 0.12 12.7 0.5 2.7 8.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) EMP24_GP25L PF01105.24 RJW67576.1 - 1.6e-41 142.2 0.0 1.8e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BAR PF03114.18 RJW67577.1 - 1.3e-24 87.2 0.0 1.6e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 RJW67577.1 - 0.028 13.6 0.2 0.093 11.8 0.1 1.7 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Prefoldin PF02996.17 RJW67577.1 - 0.047 13.6 0.8 0.069 13.1 0.4 1.6 2 0 0 2 2 2 0 Prefoldin subunit PORR PF11955.8 RJW67578.1 - 0.00042 19.4 0.0 2.9 6.7 0.0 3.1 3 0 0 3 3 3 3 Plant organelle RNA recognition domain Phosphorylase PF00343.20 RJW67579.1 - 1.1e-211 704.9 0.0 1.3e-211 704.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase BRCA-2_OB1 PF09103.10 RJW67580.1 - 2.2e-24 85.8 0.0 6.1e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 RJW67580.1 - 8.3e-19 68.0 0.0 2e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.18 RJW67580.1 - 3.7e-05 23.3 0.6 0.019 14.6 0.0 4.1 5 0 0 5 5 5 1 BRCA2 repeat BRCA-2_OB3 PF09104.10 RJW67580.1 - 0.012 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Tower PF09121.10 RJW67580.1 - 1.2 9.3 3.7 3.2 8.0 3.7 1.6 1 0 0 1 1 1 0 Tower Ig_3 PF13927.6 RJW67583.1 - 1.2e-14 54.7 8.5 7.8e-05 23.2 0.1 10.5 12 0 0 12 12 12 4 Immunoglobulin domain Ig_2 PF13895.6 RJW67583.1 - 1.4e-12 47.8 0.5 0.0056 17.0 0.1 8.5 9 0 0 9 9 9 1 Immunoglobulin domain ig PF00047.25 RJW67583.1 - 1e-07 32.0 8.4 0.0024 18.0 0.1 7.0 7 1 0 7 7 7 2 Immunoglobulin domain I-set PF07679.16 RJW67583.1 - 5.5e-07 29.6 2.7 0.00092 19.2 0.0 6.4 8 0 0 8 8 8 1 Immunoglobulin I-set domain V-set PF07686.17 RJW67583.1 - 6.9e-05 23.0 3.8 14 5.9 0.0 6.7 6 0 0 6 6 6 2 Immunoglobulin V-set domain RRM_1 PF00076.22 RJW67584.1 - 3.7e-07 29.9 0.0 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ldl_recept_a PF00057.18 RJW67586.1 - 0.02 15.1 6.3 0.04 14.2 6.3 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A KRE9 PF05390.11 RJW67587.1 - 0.044 14.5 0.9 0.067 13.9 0.9 1.2 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 Ras PF00071.22 RJW67588.1 - 9.4e-06 25.3 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW67588.1 - 8.3e-05 22.8 0.0 0.00022 21.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RJW67588.1 - 0.053 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Pkinase PF00069.25 RJW67589.1 - 6.4e-65 219.1 0.0 8.4e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67589.1 - 2.6e-29 102.3 0.0 9.3e-28 97.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW67589.1 - 5.1e-05 22.2 0.0 8.1e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase L27 PF02828.16 RJW67589.1 - 0.0005 19.8 0.7 0.0005 19.8 0.7 2.8 3 0 0 3 3 3 1 L27 domain IQ PF00612.27 RJW67590.1 - 0.0028 17.3 1.0 0.0085 15.8 1.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif EspA PF03433.13 RJW67590.1 - 0.075 12.9 3.1 0.61 9.9 0.3 2.4 2 0 0 2 2 2 0 EspA-like secreted protein RRM_1 PF00076.22 RJW67592.1 - 3.1e-17 62.2 0.2 5.8e-17 61.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW67592.1 - 0.0003 20.9 0.0 0.00088 19.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 RJW67592.1 - 0.023 14.7 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DNA_ligase_A_C PF04679.15 RJW67592.1 - 0.05 14.2 0.1 0.12 12.9 0.1 1.7 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region SUIM_assoc PF16619.5 RJW67592.1 - 0.26 11.4 4.6 0.079 13.0 0.5 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NARP1 PF12569.8 RJW67593.1 - 1e-159 532.8 6.7 2.8e-159 531.4 3.8 2.6 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 RJW67593.1 - 3.7e-12 45.4 12.0 0.00014 21.8 0.1 7.7 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW67593.1 - 2.4e-11 42.9 18.2 1.6e-05 24.6 0.1 9.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW67593.1 - 7.2e-10 38.9 29.2 0.053 14.4 0.0 11.8 10 2 2 12 12 11 1 Tetratricopeptide repeat TPR_1 PF00515.28 RJW67593.1 - 1.5e-09 37.2 19.3 2e-05 24.2 0.2 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 RJW67593.1 - 2.2e-09 37.7 23.6 0.0024 18.3 0.0 8.8 9 2 2 11 11 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW67593.1 - 1.7e-08 34.5 10.3 0.15 12.3 0.0 6.4 3 3 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RJW67593.1 - 1.9e-08 34.4 19.8 0.0011 19.2 0.8 7.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW67593.1 - 6.6e-08 32.3 6.2 0.00049 19.6 0.7 4.5 2 2 3 6 6 6 2 MalT-like TPR region TPR_11 PF13414.6 RJW67593.1 - 2.5e-07 30.3 0.0 1.9e-05 24.3 0.0 4.0 4 0 0 4 4 4 1 TPR repeat TPR_17 PF13431.6 RJW67593.1 - 3.5e-05 23.9 11.0 1.6 9.3 0.1 8.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW67593.1 - 7.3e-05 22.5 8.0 0.0055 16.6 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 RJW67593.1 - 0.00012 22.3 3.9 26 5.8 0.0 6.8 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 RJW67593.1 - 0.00068 20.2 18.0 0.037 14.7 0.0 7.6 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW67593.1 - 0.0012 18.9 7.5 0.043 14.0 0.1 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat FAT PF02259.23 RJW67593.1 - 0.003 16.8 0.1 0.23 10.6 0.0 3.1 1 1 1 3 3 3 1 FAT domain TPR_6 PF13174.6 RJW67593.1 - 0.0063 17.1 6.3 84 4.1 0.0 7.0 9 0 0 9 9 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RJW67593.1 - 0.022 14.8 4.6 1.5 9.0 0.2 5.2 6 1 1 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 RJW67593.1 - 8.3 6.4 15.2 54 3.8 0.0 6.4 7 0 0 7 7 5 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 RJW67594.1 - 2.1e-14 53.6 0.0 1.1e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 RJW67594.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase PDZ PF00595.24 RJW67595.1 - 3.8e-10 40.0 0.0 6.7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW67595.1 - 4.1e-08 32.9 0.0 8.5e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW67595.1 - 1.8e-05 25.0 0.0 3.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Neuralized PF07177.12 RJW67596.1 - 1e-20 74.2 0.0 2.5e-17 63.3 0.0 2.4 2 0 0 2 2 2 2 Neuralized TFIIF_beta PF02270.15 RJW67597.1 - 5.4e-24 84.1 0.5 7.7e-24 83.6 0.5 1.2 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain SKICH PF17751.1 RJW67598.1 - 2.1e-05 25.0 0.1 5.5e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 SKICH domain Exo_endo_phos PF03372.23 RJW67598.1 - 0.00073 19.1 0.2 0.0012 18.5 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Hist_deacetyl PF00850.19 RJW67600.1 - 4.3e-76 256.3 0.0 8.4e-76 255.4 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain RVT_1 PF00078.27 RJW67600.1 - 6.1e-35 120.7 0.0 1.5e-34 119.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hjc PF01870.18 RJW67600.1 - 0.012 15.6 0.1 0.037 14.0 0.1 1.8 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) ABC_membrane PF00664.23 RJW67601.1 - 1.5e-54 185.5 23.3 6.6e-30 104.7 12.4 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RJW67601.1 - 1.7e-30 106.3 0.0 8.6e-19 68.4 0.0 3.5 2 1 1 3 3 3 3 ABC transporter MMR_HSR1 PF01926.23 RJW67601.1 - 2.4e-05 24.4 0.1 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 RJW67601.1 - 2.5e-05 23.8 4.0 0.19 11.1 0.1 4.2 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain RVT_1 PF00078.27 RJW67601.1 - 6.7e-05 22.5 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zeta_toxin PF06414.12 RJW67601.1 - 0.00064 19.0 0.0 0.047 13.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 RJW67601.1 - 0.00089 19.7 0.3 0.67 10.3 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 RJW67601.1 - 0.0075 16.4 1.7 0.069 13.2 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 RJW67601.1 - 0.012 15.3 0.6 3.2 7.6 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 RJW67601.1 - 0.015 15.4 3.2 0.18 11.9 0.1 2.4 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 RJW67601.1 - 0.016 15.1 0.2 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 RJW67601.1 - 0.031 14.8 0.0 13 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RJW67601.1 - 0.11 11.7 0.3 0.34 10.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 RJW67601.1 - 0.14 12.4 0.6 17 5.7 0.1 3.4 2 1 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 RJW67602.1 - 2.4e-13 50.2 7.7 5.6e-13 49.0 7.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RJW67602.1 - 1.3e-09 37.6 4.3 1.3e-09 37.6 4.3 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RJW67602.1 - 1.9e-09 37.3 5.9 3.9e-09 36.2 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW67602.1 - 1e-08 35.3 4.3 2.9e-08 33.8 4.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RJW67602.1 - 1.7e-08 34.1 6.3 3.3e-08 33.2 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 RJW67602.1 - 2.3e-08 33.9 0.0 4.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 RJW67602.1 - 2.6e-08 33.7 4.6 5.9e-08 32.6 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RJW67602.1 - 1.5e-07 31.3 2.7 1.5e-07 31.3 2.7 2.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RJW67602.1 - 3.6e-05 23.5 4.6 7.6e-05 22.5 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RJW67602.1 - 0.00039 20.4 1.4 0.00097 19.1 1.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RJW67602.1 - 0.00094 19.0 8.1 0.021 14.7 8.5 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RJW67602.1 - 0.097 12.5 4.9 0.17 11.7 4.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 RJW67602.1 - 0.18 11.5 2.0 0.37 10.5 2.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 RJW67602.1 - 0.29 11.0 3.5 0.74 9.8 3.5 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 RJW67602.1 - 0.71 10.1 6.0 0.16 12.2 2.3 1.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 RJW67602.1 - 1.5 9.0 5.8 3.2 7.9 5.8 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 RJW67602.1 - 5.2 7.5 6.0 1.2 9.5 2.3 1.8 2 0 0 2 2 1 0 RING-like domain EST1_DNA_bind PF10373.9 RJW67603.1 - 7e-39 134.0 0.0 1.3e-38 133.1 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain JAB PF01398.21 RJW67603.1 - 2.7e-31 108.0 0.3 1.1e-30 106.0 0.2 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PIN_4 PF13638.6 RJW67603.1 - 4.4e-15 56.1 0.0 9.9e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 PIN domain CSN5_C PF18323.1 RJW67603.1 - 2.3e-11 44.5 0.1 9.5e-11 42.5 0.1 2.1 1 1 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain EST1 PF10374.9 RJW67603.1 - 5.6e-09 36.7 0.6 1.9e-07 31.8 0.0 2.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 Prok-JAB PF14464.6 RJW67603.1 - 2.2e-05 24.2 0.0 6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 RJW67603.1 - 0.00092 19.3 0.1 0.0025 17.9 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) TPR_12 PF13424.6 RJW67603.1 - 0.069 13.4 3.4 3.5 8.0 1.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.22 RJW67604.1 - 2.5e-159 531.3 0.0 3.7e-158 527.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RJW67604.1 - 1.1e-17 63.9 0.0 2.7e-06 26.4 0.0 4.3 4 0 0 4 4 4 4 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 RJW67604.1 - 0.00055 19.5 0.0 0.0064 16.0 0.0 2.1 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1c PF00749.21 RJW67604.1 - 0.21 10.5 0.0 0.79 8.6 0.0 1.9 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1e PF01406.19 RJW67604.1 - 0.21 10.9 0.0 5.7 6.2 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 RJW67604.1 - 0.23 10.7 0.1 2.7 7.2 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) TP6A_N PF04406.14 RJW67605.1 - 2.3e-19 69.1 0.0 2.6e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Type IIB DNA topoisomerase GCN5L1 PF06320.13 RJW67606.1 - 1.8e-27 95.7 2.3 2e-27 95.6 2.3 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Snapin_Pallidin PF14712.6 RJW67606.1 - 0.012 16.0 2.1 0.019 15.4 1.9 1.5 1 1 0 1 1 1 0 Snapin/Pallidin Bacillus_HBL PF05791.11 RJW67606.1 - 0.051 13.4 0.3 0.091 12.6 0.3 1.5 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Sec2p PF06428.11 RJW67606.1 - 0.057 13.4 1.3 0.081 12.9 1.4 1.4 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p CENP-H PF05837.12 RJW67606.1 - 2.6 8.5 6.7 3 8.3 5.6 1.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Cadherin PF00028.17 RJW67608.1 - 3.3e-26 91.5 2.6 2.6e-13 50.2 0.1 3.7 4 0 0 4 4 4 2 Cadherin domain Cadherin_pro PF08758.11 RJW67608.1 - 4.3e-06 26.8 0.0 3.1e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Cadherin prodomain like Fcf1 PF04900.12 RJW67610.1 - 2.2e-30 105.0 4.2 2.2e-30 105.0 4.2 2.0 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 RJW67610.1 - 2.3e-09 37.6 0.0 4.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 PIN like domain NB-ARC PF00931.22 RJW67612.1 - 2.1e-14 53.3 0.0 6.9e-14 51.6 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain APAF1_C PF17908.1 RJW67612.1 - 5.3e-11 42.7 0.4 3.6e-08 33.5 0.1 2.6 2 0 0 2 2 2 2 APAF-1 helical domain WD40 PF00400.32 RJW67612.1 - 7.9e-09 36.0 21.4 0.0001 23.0 0.8 9.1 9 0 0 9 9 9 2 WD domain, G-beta repeat CARD PF00619.21 RJW67612.1 - 8.6e-07 28.9 0.0 1.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 RJW67612.1 - 2.8e-06 27.2 0.0 5.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Caspase recruitment domain AAA_16 PF13191.6 RJW67612.1 - 2.3e-05 24.8 0.0 6.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 RJW67612.1 - 0.0084 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 RJW67612.1 - 0.08 13.2 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain SQHop_cyclase_C PF13243.6 RJW67612.1 - 0.11 11.6 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain NDUF_B7 PF05676.13 RJW67613.1 - 0.03 14.1 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Asp PF00026.23 RJW67614.1 - 8.2e-38 130.6 0.1 9.3e-38 130.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW67614.1 - 0.0012 19.2 1.2 1.1 9.4 0.1 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RJW67614.1 - 0.014 16.0 0.3 0.1 13.3 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 RJW67614.1 - 0.024 14.4 0.0 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Tetraspanin PF00335.20 RJW67616.1 - 7.6e-18 65.1 7.7 9e-18 64.8 7.7 1.1 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.6 RJW67616.1 - 0.13 12.0 4.9 0.11 12.3 3.6 1.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4191 PF13829.6 RJW67616.1 - 0.78 9.0 4.4 1.4 8.2 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2207 PF09972.9 RJW67616.1 - 1.1 7.9 4.8 1.6 7.4 4.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 RJW67616.1 - 2.2 8.3 6.6 4.9 7.2 6.6 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III CRPA PF05745.11 RJW67616.1 - 2.3 8.2 11.4 4.3 7.3 11.4 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) tRNA-synt_1 PF00133.22 RJW67617.1 - 4.5e-172 573.4 0.0 5.4e-172 573.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RJW67617.1 - 3.6e-13 49.7 0.0 6.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RJW67617.1 - 7.3e-06 25.0 0.0 0.052 12.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 RJW67617.1 - 2.3e-05 23.9 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Tetraspanin PF00335.20 RJW67618.1 - 7.2e-16 58.6 6.0 8.7e-16 58.3 6.0 1.0 1 0 0 1 1 1 1 Tetraspanin family PRCC PF10253.9 RJW67619.1 - 5.1e-20 73.2 8.5 5.1e-20 73.2 8.5 2.5 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting P34-Arc PF04045.14 RJW67620.1 - 3.7e-94 314.9 1.0 4.4e-94 314.7 1.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc GST_N_3 PF13417.6 RJW67624.1 - 2.1e-07 31.3 0.0 4.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RJW67624.1 - 2e-06 28.0 0.0 4.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RJW67624.1 - 2.2e-06 27.9 0.0 3.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RJW67624.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RJW67624.1 - 0.0021 18.2 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RJW67624.1 - 0.0073 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 RJW67624.1 - 0.072 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_5 PF16865.5 RJW67624.1 - 0.22 12.1 0.0 0.3 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 7tm_1 PF00001.21 RJW67625.1 - 0.024 13.9 1.2 0.039 13.3 1.2 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) EF-hand_1 PF00036.32 RJW67626.1 - 8.5e-34 112.6 13.8 9.3e-10 37.4 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW67626.1 - 2e-29 101.8 13.6 6.3e-14 52.2 0.1 2.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RJW67626.1 - 1.1e-26 90.4 7.6 1.1e-07 31.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RJW67626.1 - 1.6e-22 79.1 11.2 7.8e-13 48.1 1.8 3.4 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW67626.1 - 8.4e-22 75.6 7.0 1.4e-06 27.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RJW67626.1 - 1.8e-13 50.6 0.4 2.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RJW67626.1 - 1.5e-11 44.1 3.5 0.0013 18.6 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RJW67626.1 - 4.4e-10 39.6 0.1 9.8e-06 25.7 0.0 2.5 2 1 0 2 2 2 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 RJW67626.1 - 7.3e-07 29.5 0.9 0.0072 16.6 0.4 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 RJW67626.1 - 2.3e-05 24.4 2.1 0.096 12.6 0.0 2.4 1 1 0 2 2 2 2 Tellurite resistance protein TerB SurA_N_3 PF13624.6 RJW67626.1 - 3.6e-05 23.6 0.5 0.0011 18.7 0.2 2.0 1 1 1 2 2 2 2 SurA N-terminal domain SurA_N_2 PF13623.6 RJW67626.1 - 0.00011 22.0 0.5 0.0021 17.9 0.2 2.1 1 1 1 2 2 2 1 SurA N-terminal domain Adenine_glyco PF03352.13 RJW67626.1 - 0.0041 16.9 0.4 0.019 14.8 0.2 1.8 1 1 1 2 2 2 1 Methyladenine glycosylase Vps23_core PF09454.10 RJW67626.1 - 0.006 16.5 0.1 0.31 11.0 0.0 2.8 2 1 0 2 2 2 1 Vps23 core domain Caleosin PF05042.13 RJW67626.1 - 0.026 14.5 0.9 4.9 7.1 0.0 2.9 1 1 1 3 3 3 0 Caleosin related protein EF-hand_14 PF17959.1 RJW67626.1 - 0.089 13.1 0.9 12 6.3 0.0 2.5 1 1 1 3 3 3 0 EF-hand domain DUF1456 PF07308.13 RJW67626.1 - 0.093 13.1 0.4 13 6.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) EF-hand_10 PF14788.6 RJW67626.1 - 0.59 10.0 4.2 0.48 10.3 0.5 2.6 2 1 1 3 3 3 0 EF hand DUF4834 PF16118.5 RJW67626.1 - 3.3 8.7 9.7 1.4 9.9 3.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Ig_3 PF13927.6 RJW67627.1 - 4e-28 97.8 3.3 8.6e-11 42.3 0.1 5.8 5 1 0 5 5 5 3 Immunoglobulin domain ig PF00047.25 RJW67627.1 - 7.7e-20 70.9 2.0 4.7e-08 33.1 0.1 4.5 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 RJW67627.1 - 6.7e-19 67.8 0.1 5.8e-06 26.3 0.0 4.5 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW67627.1 - 3.5e-12 46.5 6.6 0.0088 16.4 0.2 6.0 4 2 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 RJW67627.1 - 1.1e-11 44.8 2.0 0.00056 20.1 0.1 5.2 4 1 0 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 RJW67627.1 - 1.1e-06 28.1 0.4 0.43 10.2 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin domain Ig_4 PF16680.5 RJW67627.1 - 0.0013 18.9 0.4 5.9 7.2 0.0 3.9 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 RJW67627.1 - 0.003 17.6 0.1 0.037 14.1 0.0 2.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RJW67627.1 - 0.0061 16.6 0.1 0.41 10.7 0.0 3.2 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain fn3 PF00041.21 RJW67627.1 - 0.0064 16.8 0.3 0.048 14.0 0.0 2.6 2 0 0 2 2 2 1 Fibronectin type III domain AGH PF17558.2 RJW67627.1 - 0.04 14.1 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Androgenic gland hormone NTPase_1 PF03266.15 RJW67628.1 - 2.5e-34 118.6 0.0 6.7e-33 114.0 0.0 2.3 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.6 RJW67628.1 - 4.3e-07 30.5 0.0 8.7e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RJW67628.1 - 6.7e-06 26.4 0.5 0.00014 22.2 0.5 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 RJW67628.1 - 5.2e-05 23.2 0.0 0.0023 17.9 0.0 2.2 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 RJW67628.1 - 7.6e-05 22.2 0.0 0.079 12.3 0.0 2.1 2 0 0 2 2 2 2 KaiC AAA PF00004.29 RJW67628.1 - 0.00033 21.1 1.2 0.0047 17.4 1.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RJW67628.1 - 0.00082 19.7 0.1 0.01 16.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 RJW67628.1 - 0.0026 17.7 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 RJW67628.1 - 0.0031 17.7 0.0 0.007 16.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 RJW67628.1 - 0.0036 17.0 0.9 0.25 10.9 0.2 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 RJW67628.1 - 0.0045 17.0 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ArsA_ATPase PF02374.15 RJW67628.1 - 0.0069 15.6 0.1 0.022 14.0 0.0 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_30 PF13604.6 RJW67628.1 - 0.0088 15.8 0.0 0.035 13.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RJW67628.1 - 0.009 15.4 0.1 0.021 14.2 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 RJW67628.1 - 0.01 15.6 0.1 0.075 12.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RJW67628.1 - 0.011 15.7 0.1 0.031 14.2 0.1 1.7 1 1 0 1 1 1 0 RsgA GTPase MobB PF03205.14 RJW67628.1 - 0.012 15.6 0.2 0.025 14.5 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 RJW67628.1 - 0.012 15.4 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein MeaB PF03308.16 RJW67628.1 - 0.012 14.6 0.1 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 RJW67628.1 - 0.015 15.3 0.1 0.065 13.1 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 RJW67628.1 - 0.016 15.2 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RJW67628.1 - 0.023 13.9 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 RJW67628.1 - 0.023 14.8 0.1 0.033 14.3 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 RJW67628.1 - 0.025 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 RJW67628.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RJW67628.1 - 0.029 14.1 0.2 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RJW67628.1 - 0.03 14.6 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RJW67628.1 - 0.043 14.2 0.7 0.12 12.7 0.7 1.9 1 1 0 1 1 1 0 AAA domain GvpD PF07088.11 RJW67628.1 - 0.06 11.9 0.0 0.077 11.6 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein DUF2075 PF09848.9 RJW67628.1 - 0.069 12.4 0.2 0.17 11.1 0.2 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 RJW67628.1 - 0.07 13.5 0.0 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF5584 PF17822.1 RJW67628.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5584) RuvB_N PF05496.12 RJW67628.1 - 0.1 12.3 0.1 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 RJW67628.1 - 0.11 12.1 1.1 0.25 10.9 0.2 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 RJW67628.1 - 0.13 12.8 0.1 0.17 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 RJW67628.1 - 0.17 11.9 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 RJW67628.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RVT_1 PF00078.27 RJW67629.1 - 0.0029 17.2 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tetraspanin PF00335.20 RJW67631.1 - 6.9e-26 91.4 11.7 1.1e-25 90.7 11.7 1.3 1 0 0 1 1 1 1 Tetraspanin family Yip1 PF04893.17 RJW67631.1 - 0.0028 17.4 12.3 0.092 12.5 3.4 2.9 3 0 0 3 3 3 2 Yip1 domain SLATT_4 PF18186.1 RJW67631.1 - 0.16 11.6 0.2 0.4 10.3 0.2 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 ABC2_membrane_3 PF12698.7 RJW67631.1 - 4.3 6.3 14.9 9.6 5.2 14.9 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein P34-Arc PF04045.14 RJW67633.1 - 1.6e-55 188.4 0.0 2.3e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc RVT_1 PF00078.27 RJW67633.1 - 0.017 14.6 0.3 0.052 13.1 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tetraspanin PF00335.20 RJW67634.1 - 1.1e-07 31.8 0.4 2e-07 31.0 0.4 1.3 1 0 0 1 1 1 1 Tetraspanin family Usp PF00582.26 RJW67638.1 - 5.4e-09 36.7 0.0 1e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family Sucrose_synth PF00862.19 RJW67639.1 - 0.00034 19.1 1.5 0.00034 19.1 1.5 2.1 2 0 0 2 2 2 1 Sucrose synthase PMC2NT PF08066.12 RJW67639.1 - 0.19 12.5 5.7 0.67 10.7 1.2 3.3 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF745 PF05335.13 RJW67639.1 - 1.2 8.9 29.7 3.3 7.4 6.2 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Peptidase_C50 PF03568.17 RJW67640.1 - 2.1e-48 165.4 0.2 3.8e-43 148.1 0.0 2.7 1 1 1 2 2 2 2 Peptidase family C50 Pap_E4 PF02711.14 RJW67640.1 - 0.14 13.1 2.3 0.52 11.3 2.3 2.1 1 0 0 1 1 1 0 E4 protein RVT_1 PF00078.27 RJW67642.1 - 3.5e-46 157.5 0.0 5.2e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) mTERF PF02536.14 RJW67642.1 - 6.2e-06 25.4 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 mTERF Hjc PF01870.18 RJW67642.1 - 0.037 14.0 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) ASC PF00858.24 RJW67643.1 - 1e-46 159.8 0.3 2e-46 158.9 0.3 1.4 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DFRP_C PF16543.5 RJW67643.1 - 0.89 10.1 3.7 11 6.6 1.8 2.7 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 zf-C3H2C3 PF17122.5 RJW67645.1 - 0.068 13.2 4.4 0.17 12.0 4.4 1.7 1 0 0 1 1 1 0 Zinc-finger Abhydrolase_1 PF00561.20 RJW67646.1 - 3.2e-20 72.9 0.1 1.1e-19 71.1 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RJW67646.1 - 2.1e-18 67.7 0.4 7.4e-18 66.0 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RJW67646.1 - 3.7e-12 46.0 0.0 9.1e-12 44.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 RJW67646.1 - 0.0013 17.5 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 RJW67646.1 - 0.0031 17.4 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 RJW67646.1 - 0.0066 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 RJW67646.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2974 PF11187.8 RJW67646.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 RJW67646.1 - 0.026 14.3 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 RJW67646.1 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF915 PF06028.11 RJW67646.1 - 0.24 10.7 0.0 0.44 9.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Cyclin_N PF00134.23 RJW67647.1 - 6.7e-21 74.4 2.1 1.4e-20 73.3 0.6 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RJW67647.1 - 0.002 18.2 0.3 0.05 13.7 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Ion_trans PF00520.31 RJW67650.1 - 3.6e-13 49.3 11.0 5e-13 48.9 11.0 1.1 1 0 0 1 1 1 1 Ion transport protein UPF0182 PF03699.13 RJW67650.1 - 0.2 9.7 3.5 0.3 9.2 3.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Ank_2 PF12796.7 RJW67652.1 - 2.2e-80 265.3 17.8 1.1e-15 57.9 1.0 8.4 4 3 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW67652.1 - 1.8e-73 242.0 13.7 2.2e-11 44.0 0.2 10.0 7 2 4 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW67652.1 - 7.3e-62 198.0 21.8 0.00017 21.8 0.0 14.6 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 RJW67652.1 - 6.4e-58 192.1 23.9 1.6e-08 34.7 0.0 12.9 3 3 10 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 RJW67652.1 - 4.2e-57 188.2 25.9 1.2e-05 25.5 0.0 14.2 14 0 0 14 14 14 13 Ankyrin repeat DUF3447 PF11929.8 RJW67652.1 - 0.023 14.6 0.7 5.9 6.9 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) XPC-binding PF09280.11 RJW67652.1 - 0.034 13.9 0.4 2.5 7.9 0.0 3.1 3 0 0 3 3 3 0 XPC-binding domain ACP_PD PF04336.12 RJW67654.1 - 0.28 11.6 2.4 15 6.1 0.1 3.4 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase HALZ PF02183.18 RJW67654.1 - 0.91 9.8 15.7 3.4 8.0 0.4 5.4 5 0 0 5 5 5 0 Homeobox associated leucine zipper DUF641 PF04859.12 RJW67654.1 - 1.6 9.1 13.1 1.2 9.5 0.6 3.8 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Fez1 PF06818.15 RJW67654.1 - 7 7.0 22.6 9.8 6.6 13.2 4.1 3 1 0 3 3 3 0 Fez1 DUF1664 PF07889.12 RJW67655.1 - 0.018 15.0 6.4 8.8 6.4 0.0 5.3 7 0 0 7 7 7 0 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.19 RJW67655.1 - 0.029 12.2 2.5 3.6 5.3 0.0 2.9 3 0 0 3 3 3 0 Myosin tail ATG16 PF08614.11 RJW67655.1 - 0.49 10.6 13.8 4.4 7.5 0.1 5.4 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 RJW67655.1 - 2.4 8.6 5.0 32 5.0 0.0 5.2 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) eIF3_subunit PF08597.10 RJW67656.1 - 4.8e-39 134.7 12.6 5.4e-39 134.6 12.6 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Pet20 PF08692.10 RJW67656.1 - 0.061 14.0 0.2 0.13 13.0 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial protein Pet20 SR-25 PF10500.9 RJW67656.1 - 1.9 8.0 9.0 0.11 12.1 2.9 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 RJW67657.1 - 7.7e-46 156.4 0.0 1.6e-45 155.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMF_TATA_bd PF12325.8 RJW67657.1 - 0.0069 16.6 11.1 0.0069 16.6 11.1 8.6 8 1 3 11 11 11 1 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 RJW67657.1 - 0.0081 16.7 19.7 0.0081 16.7 19.7 6.5 5 3 1 6 6 6 1 Apg6 coiled-coil region Flg_hook PF02120.16 RJW67657.1 - 3.3 7.7 10.9 0.14 12.1 1.7 3.4 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Flagellin_C PF00700.21 RJW67657.1 - 3.3 8.1 10.2 1.1 9.6 0.1 4.7 4 1 0 4 4 4 0 Bacterial flagellin C-terminal helical region PALP PF00291.25 RJW67659.1 - 1.7e-60 204.9 0.1 2.6e-60 204.3 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RRM_1 PF00076.22 RJW67659.1 - 2e-21 75.6 0.0 8.8e-16 57.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 RJW67659.1 - 0.00039 20.4 0.1 0.014 15.4 0.0 2.6 3 0 0 3 3 3 1 RNA binding domain RRM_7 PF16367.5 RJW67659.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RhoGAP PF00620.27 RJW67663.1 - 7.5e-21 74.5 0.1 4.3e-20 72.1 0.1 2.0 1 1 0 1 1 1 1 RhoGAP domain TRAM_LAG1_CLN8 PF03798.16 RJW67664.1 - 1.2e-09 38.2 15.7 1.4e-09 38.0 15.7 1.0 1 0 0 1 1 1 1 TLC domain Rotavirus_VP1 PF12289.8 RJW67664.1 - 0.26 10.3 1.2 0.32 10.0 0.7 1.3 1 1 0 1 1 1 0 Rotavirus VP1 C-terminal domain 14-3-3 PF00244.20 RJW67665.1 - 1e-09 38.2 0.2 1e-09 38.2 0.2 1.4 2 0 0 2 2 2 1 14-3-3 protein RVT_1 PF00078.27 RJW67666.1 - 1.1e-06 28.3 0.1 0.034 13.7 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_UBOX PF13445.6 RJW67666.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 RING-type zinc-finger DnaJ PF00226.31 RJW67668.1 - 3.4e-22 78.3 0.9 3.4e-22 78.3 0.9 2.5 3 0 0 3 3 3 1 DnaJ domain TPR_19 PF14559.6 RJW67668.1 - 7.3e-08 32.8 4.3 7.5e-05 23.2 0.1 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW67668.1 - 4.7e-07 30.1 0.5 0.77 10.7 0.2 4.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW67668.1 - 9.6e-07 28.5 1.4 0.17 12.0 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW67668.1 - 3.4e-05 24.4 0.0 0.034 14.8 0.4 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 RJW67668.1 - 0.00013 22.2 3.1 0.0012 19.1 0.1 3.1 2 2 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW67668.1 - 0.00018 21.7 6.5 0.019 15.2 1.1 3.4 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RJW67668.1 - 0.0019 18.7 4.5 4.2 8.2 0.0 5.2 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 RJW67668.1 - 0.0041 17.4 3.2 0.0044 17.3 0.0 2.9 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RJW67668.1 - 0.0049 16.6 2.9 0.55 10.1 0.1 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat DUF982 PF06169.12 RJW67668.1 - 0.021 14.8 1.2 0.46 10.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF982) TPR_8 PF13181.6 RJW67668.1 - 0.028 14.6 5.7 1.1 9.7 0.0 4.5 5 1 1 6 6 4 0 Tetratricopeptide repeat DUF4363 PF14276.6 RJW67668.1 - 0.043 13.9 2.0 1.3 9.2 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) FRB_dom PF08771.11 RJW67668.1 - 0.046 14.1 0.9 2.7 8.4 0.1 2.5 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain FlbT PF07378.11 RJW67668.1 - 0.16 12.1 2.8 1.6 8.8 0.6 2.4 2 0 0 2 2 2 0 Flagellar protein FlbT DUF2515 PF10720.9 RJW67668.1 - 0.16 11.1 1.7 0.22 10.7 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2515) TPR_12 PF13424.6 RJW67668.1 - 0.71 10.2 3.9 6.6 7.1 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat KilA-N PF04383.13 RJW67668.1 - 1.1 9.1 3.5 0.5 10.2 0.6 1.9 2 1 0 2 2 2 0 KilA-N domain Band_7 PF01145.25 RJW67671.1 - 2.6e-22 79.7 0.0 2.6e-22 79.7 0.0 2.8 3 0 0 3 3 3 1 SPFH domain / Band 7 family Flot PF15975.5 RJW67671.1 - 7.1e-09 35.9 4.5 7.1e-09 35.9 4.5 3.9 2 2 2 4 4 4 2 Flotillin Band_7_1 PF13421.6 RJW67671.1 - 0.08 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family GOLD_2 PF13897.6 RJW67674.1 - 1.1e-52 178.2 0.7 6.8e-52 175.6 0.7 2.1 1 1 0 1 1 1 1 Golgi-dynamics membrane-trafficking PaO PF08417.12 RJW67674.1 - 0.2 11.8 2.9 0.94 9.7 0.0 2.8 2 1 0 3 3 3 0 Pheophorbide a oxygenase PilM PF07419.12 RJW67674.1 - 1.4 9.1 3.1 2.2 8.5 3.1 1.3 1 0 0 1 1 1 0 PilM APH PF01636.23 RJW67675.1 - 4.4e-17 62.8 0.0 6.2e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RJW67675.1 - 0.00035 20.2 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase SAP30_Sin3_bdg PF13867.6 RJW67675.1 - 0.19 12.1 0.6 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Hairy_orange PF07527.13 RJW67675.1 - 0.33 11.2 0.0 0.33 11.2 0.0 2.1 3 0 0 3 3 3 0 Hairy Orange Ank_2 PF12796.7 RJW67676.1 - 1.3e-77 256.4 7.5 4.6e-14 52.8 0.0 8.6 3 2 6 9 9 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW67676.1 - 1.8e-67 222.9 16.1 3.6e-09 37.0 0.0 10.9 7 1 3 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW67676.1 - 2.1e-56 187.2 23.0 9.5e-08 32.2 0.1 10.7 5 3 6 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 RJW67676.1 - 1.3e-54 180.3 23.4 0.00037 20.8 0.2 15.0 14 0 0 14 14 14 11 Ankyrin repeat Ank_3 PF13606.6 RJW67676.1 - 2.3e-38 125.8 21.2 0.16 12.6 0.0 16.5 16 0 0 16 16 16 9 Ankyrin repeat NACHT PF05729.12 RJW67676.1 - 0.00011 22.2 0.0 0.0089 16.0 0.0 2.7 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 RJW67676.1 - 0.00022 21.5 0.0 0.0013 19.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RJW67676.1 - 0.0021 18.4 0.1 0.0052 17.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RJW67676.1 - 0.0095 16.3 0.0 0.049 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 RJW67676.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 RJW67676.1 - 0.025 14.8 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 RJW67676.1 - 0.032 14.7 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RJW67676.1 - 0.037 14.6 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RJW67676.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 RJW67676.1 - 0.045 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RJW67676.1 - 0.048 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RJW67676.1 - 0.07 13.7 0.1 0.28 11.7 0.0 2.1 2 0 0 2 2 1 0 ABC transporter NB-ARC PF00931.22 RJW67676.1 - 0.081 12.1 0.2 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 RJW67676.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 RJW67676.1 - 0.21 11.5 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 NTPase DUF720 PF05302.11 RJW67676.1 - 0.23 11.3 0.7 0.8 9.6 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF720) RVT_1 PF00078.27 RJW67677.1 - 2.3e-24 86.2 0.0 8.7e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 RJW67680.1 - 2e-10 40.9 0.0 2.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW67680.1 - 1.7e-09 37.6 0.0 2.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4817 PF16087.5 RJW67681.1 - 7.6e-12 44.9 0.0 1.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_IclR PF09339.10 RJW67681.1 - 0.0004 20.1 0.2 0.0013 18.5 0.2 1.9 1 0 0 1 1 1 1 IclR helix-turn-helix domain KH_1 PF00013.29 RJW67682.1 - 0.031 14.1 1.5 0.059 13.2 1.5 1.4 1 0 0 1 1 1 0 KH domain KH_8 PF17903.1 RJW67682.1 - 0.07 13.2 0.1 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Krr1 KH1 domain Hist_deacetyl PF00850.19 RJW67683.1 - 2.2e-73 247.4 0.3 2.2e-73 247.4 0.3 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Y_phosphatase PF00102.27 RJW67684.1 - 8.5e-41 140.1 0.0 1.6e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RJW67684.1 - 0.0014 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RJW67684.1 - 0.034 14.2 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RJW67684.1 - 0.039 13.9 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family SSF PF00474.17 RJW67685.1 - 9.4e-26 90.6 26.8 4e-25 88.5 26.8 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family Med19 PF10278.9 RJW67686.1 - 5.9e-35 120.8 0.0 5.9e-35 120.8 0.0 2.4 2 1 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 Y_phosphatase PF00102.27 RJW67687.1 - 1e-55 188.9 0.0 2.2e-55 187.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 RJW67687.1 - 5e-17 62.0 14.6 1.1e-07 32.1 0.1 9.4 9 0 0 9 9 9 5 Fibronectin type III domain RVT_1 PF00078.27 RJW67687.1 - 1.2e-05 25.0 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DSPc PF00782.20 RJW67687.1 - 0.0002 21.1 0.0 0.00058 19.7 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain LSM14 PF12701.7 RJW67688.1 - 6.5e-09 35.8 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 RJW67688.1 - 0.096 13.6 0.0 6.5 7.7 0.0 2.4 2 0 0 2 2 2 0 FDF domain eIF-3_zeta PF05091.12 RJW67691.1 - 3.2e-161 537.9 0.0 1.6e-160 535.6 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 RJW67691.1 - 0.023 14.2 0.0 0.066 12.7 0.0 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus RRM_1 PF00076.22 RJW67693.1 - 2.9e-09 36.6 0.0 0.00025 20.8 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exo_endo_phos_2 PF14529.6 RJW67693.1 - 3.6e-05 23.6 0.1 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RRM_7 PF16367.5 RJW67693.1 - 0.046 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif DnaJ PF00226.31 RJW67695.1 - 4.6e-14 52.3 0.0 1.1e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Baculo_PEP_C PF04513.12 RJW67696.1 - 0.21 11.6 3.8 1.5 8.9 0.2 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 RJW67696.1 - 0.23 11.5 4.8 10 6.2 0.1 3.7 4 1 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) fn3 PF00041.21 RJW67697.1 - 0.00029 21.1 6.1 0.73 10.2 0.0 5.5 6 0 0 6 6 6 2 Fibronectin type III domain PP28 PF10252.9 RJW67698.1 - 0.00013 22.4 9.9 0.0004 20.8 10.0 1.7 1 1 0 1 1 1 1 Casein kinase substrate phosphoprotein PP28 GDE_C PF06202.14 RJW67699.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase RRM_1 PF00076.22 RJW67701.1 - 3.8e-16 58.7 0.0 1.7e-05 24.5 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAFII55_N PF04658.13 RJW67702.1 - 1.7e-51 174.1 0.1 2.3e-51 173.7 0.1 1.2 1 0 0 1 1 1 1 TAFII55 protein conserved region RNase_PH PF01138.21 RJW67704.1 - 5.5e-06 26.9 0.0 1.2e-05 25.8 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Cornifin PF02389.15 RJW67705.1 - 4.8 7.4 21.7 7 6.9 11.6 2.0 1 1 1 2 2 2 0 Cornifin (SPRR) family Lactamase_B_2 PF12706.7 RJW67707.1 - 6.7e-08 32.3 0.1 8.5e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RJW67707.1 - 0.0018 18.3 0.7 0.0032 17.5 0.7 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Asp PF00026.23 RJW67710.1 - 9.3e-53 179.7 0.0 1.1e-52 179.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW67710.1 - 9.2e-08 32.5 0.1 9.6e-06 25.9 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RJW67710.1 - 7.7e-05 23.3 0.0 0.0036 17.9 0.0 2.7 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW67710.1 - 0.074 13.6 0.0 3.1 8.4 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 RJW67710.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Dynein_light PF01221.18 RJW67712.1 - 4.1e-41 139.2 0.7 4.8e-41 139.0 0.7 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 EFhand_Ca_insen PF08726.10 RJW67712.1 - 0.004 17.2 0.7 0.007 16.4 0.7 1.4 1 0 0 1 1 1 1 Ca2+ insensitive EF hand TM231 PF10149.9 RJW67713.1 - 0.00046 19.6 0.1 0.00055 19.4 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 BRO1 PF03097.18 RJW67716.1 - 6.9e-90 301.7 0.0 4.3e-80 269.4 0.0 2.2 2 0 0 2 2 2 2 BRO1-like domain Y_phosphatase PF00102.27 RJW67716.1 - 9.8e-33 113.7 0.2 4.7e-19 68.9 0.0 3.4 3 0 0 3 3 3 2 Protein-tyrosine phosphatase ALIX_LYPXL_bnd PF13949.6 RJW67716.1 - 8.2e-30 104.1 6.1 5.1e-28 98.2 7.4 2.8 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV Apolipoprotein PF01442.18 RJW67716.1 - 0.23 11.3 4.2 0.096 12.6 0.2 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain FlgM PF04316.13 RJW67716.1 - 0.25 11.7 0.8 4.5 7.7 0.1 2.9 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Peptidase_C1 PF00112.23 RJW67717.1 - 1.9e-61 207.9 2.7 2.3e-61 207.7 2.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RJW67717.1 - 0.015 14.1 4.5 0.56 8.9 1.8 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 RJW67718.1 - 1.3e-64 218.3 3.2 1.6e-64 218.0 3.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RJW67718.1 - 0.0018 17.1 2.1 0.18 10.6 0.6 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 RJW67719.1 - 2.8e-61 207.4 5.1 3.5e-61 207.1 5.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RJW67719.1 - 0.019 13.8 1.8 0.34 9.6 0.2 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Ribosomal_S18 PF01084.20 RJW67720.1 - 6.4e-10 39.1 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Dynein_light PF01221.18 RJW67721.1 - 7e-38 128.8 3.3 7.7e-38 128.7 3.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ion_trans PF00520.31 RJW67722.1 - 4.7e-27 94.8 10.0 7.5e-27 94.1 10.0 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW67722.1 - 4.1e-11 42.7 1.6 1.1e-10 41.4 1.6 1.8 1 0 0 1 1 1 1 Ion channel PAS_9 PF13426.7 RJW67722.1 - 4.1e-10 39.9 0.0 1.3e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 RJW67722.1 - 1.1e-09 38.2 0.0 2.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS PF00989.25 RJW67722.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold SAND PF01342.21 RJW67722.1 - 0.057 13.1 2.0 8.1 6.2 0.0 3.9 4 0 0 4 4 4 0 SAND domain GAS PF13851.6 RJW67722.1 - 0.085 12.2 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IRK PF01007.20 RJW67722.1 - 2.1 8.1 8.3 0.17 11.7 2.1 2.2 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Dynein_light PF01221.18 RJW67723.1 - 1.9e-32 111.4 0.3 2e-32 111.3 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nup192 PF11894.8 RJW67725.1 - 2.8e-121 406.1 0.0 5.5e-73 246.0 0.0 3.0 2 1 0 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF218 PF02698.17 RJW67725.1 - 0.051 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 DUF218 domain RNA_pol_Rpb1_7 PF04990.12 RJW67727.1 - 0.079 13.0 0.1 0.099 12.6 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 Dynein_light PF01221.18 RJW67728.1 - 3.2e-40 136.3 0.7 3.6e-40 136.2 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Swm2 PF17083.5 RJW67728.1 - 0.038 14.0 0.1 0.046 13.7 0.1 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 Imm48 PF15574.6 RJW67728.1 - 0.08 12.7 0.1 0.11 12.3 0.1 1.3 1 1 0 1 1 1 0 Immunity protein 48 Dynein_light PF01221.18 RJW67729.1 - 3.8e-27 94.4 0.3 6.4e-27 93.7 0.3 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 AAA_lid_7 PF17867.1 RJW67729.1 - 0.035 14.3 0.1 0.098 12.9 0.1 1.8 2 0 0 2 2 2 0 Midasin AAA lid domain 7tm_1 PF00001.21 RJW67731.1 - 1.2e-11 44.5 3.7 1.7e-11 44.0 3.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW67731.1 - 3.1e-06 26.7 1.9 0.0019 17.6 0.0 2.5 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.15 RJW67731.1 - 0.00025 21.0 0.5 0.00051 20.1 0.5 1.5 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa DUF996 PF06195.13 RJW67731.1 - 0.2 12.0 1.2 2 8.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Asp PF00026.23 RJW67732.1 - 1.9e-31 109.6 0.0 2.6e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW67732.1 - 0.029 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Peptidase_C1 PF00112.23 RJW67733.1 - 9e-120 398.6 6.3 1.9e-61 207.9 1.2 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RJW67733.1 - 2.2e-05 23.4 6.6 0.22 10.2 0.2 3.1 3 0 0 3 3 3 3 Peptidase C1-like family MRP-S23 PF10484.9 RJW67733.1 - 0.36 11.1 1.2 21 5.4 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 Dynein_light PF01221.18 RJW67734.1 - 5.4e-38 129.2 4.4 6e-38 129.0 4.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 RJW67735.1 - 3e-75 252.6 0.0 4.2e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 RJW67735.1 - 1.5e-43 148.5 0.3 2.6e-43 147.8 0.3 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain ATP-gua_Ptrans PF00217.19 RJW67737.1 - 5.8e-161 532.4 0.0 3.6e-80 268.4 0.0 2.1 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 RJW67737.1 - 2.6e-28 98.2 0.0 4.4e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain HSP20 PF00011.21 RJW67738.1 - 1.3e-22 79.8 0.1 7.6e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RJW67738.1 - 7.9e-06 25.3 0.1 0.001 18.6 0.0 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA CENP-Q PF13094.6 RJW67738.1 - 0.34 11.1 2.1 0.69 10.1 2.1 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Pkinase PF00069.25 RJW67739.1 - 2e-46 158.5 0.0 2.4e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67739.1 - 3.2e-23 82.3 0.0 3.8e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW67739.1 - 0.00021 21.3 0.0 0.033 14.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW67739.1 - 0.00076 18.5 0.1 0.0043 16.0 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 RJW67739.1 - 0.037 13.6 0.0 0.077 12.6 0.0 1.6 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 RJW67739.1 - 0.044 13.1 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 RJW67739.1 - 0.047 13.0 0.0 0.098 12.0 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RJW67739.1 - 0.066 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 RJW67739.1 - 0.087 12.4 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 RJW67739.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 ThiF PF00899.21 RJW67741.1 - 8.6e-21 74.4 0.0 1.1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family Glypican PF01153.19 RJW67742.1 - 0.0067 15.3 0.9 0.01 14.8 0.9 1.2 1 0 0 1 1 1 1 Glypican TCL1_MTCP1 PF01840.17 RJW67744.1 - 0.13 11.9 0.7 4.3 7.0 0.2 2.2 1 1 1 2 2 2 0 TCL1/MTCP1 family Glypican PF01153.19 RJW67745.1 - 1.1e-08 34.4 0.0 1.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Glypican Taeniidae_ag PF05596.11 RJW67745.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Taeniidae antigen ELMO_CED12 PF04727.13 RJW67746.1 - 3e-15 56.8 0.0 5.7e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 ELMO/CED-12 family TIP41 PF04176.13 RJW67750.1 - 1.8e-53 180.6 0.0 2.2e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Sushi PF00084.20 RJW67751.1 - 5.1e-39 132.7 30.3 9.9e-11 42.1 0.4 8.0 8 1 0 8 8 8 6 Sushi repeat (SCR repeat) Asp PF00026.23 RJW67752.1 - 4.8e-32 111.6 0.0 5.6e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease WD40 PF00400.32 RJW67756.1 - 0.0032 18.3 10.6 4 8.5 0.1 6.2 5 1 1 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW67756.1 - 0.013 15.8 0.0 2.4 8.5 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf_UBZ PF18439.1 RJW67757.1 - 3.8e-05 23.2 10.2 0.14 11.8 0.1 5.0 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-TRAF PF02176.18 RJW67757.1 - 0.00094 19.8 4.5 0.00094 19.8 4.5 3.2 2 1 1 3 3 3 2 TRAF-type zinc finger zf-CHCC PF10276.9 RJW67757.1 - 0.048 13.7 2.2 6.2 7.0 0.3 3.1 2 0 0 2 2 2 0 Zinc-finger domain zf-FPG_IleRS PF06827.14 RJW67757.1 - 0.13 12.1 2.9 9.2 6.2 0.1 2.9 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS PRP21_like_P PF12230.8 RJW67757.1 - 0.22 11.4 3.1 6.1 6.6 0.1 3.2 1 1 2 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein DUF2039 PF10217.9 RJW67757.1 - 0.32 11.4 9.9 0.088 13.2 5.9 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF4796 PF16044.5 RJW67757.1 - 2.1 7.9 9.0 1.2 8.7 0.1 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4796) LRR_8 PF13855.6 RJW67760.1 - 1e-22 79.7 11.8 7.9e-10 38.4 5.3 3.6 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RJW67760.1 - 6.3e-13 48.7 6.6 0.0003 21.1 0.4 4.3 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW67760.1 - 9.1e-09 34.7 13.0 0.19 12.4 0.0 7.4 6 0 0 6 6 6 2 Leucine Rich Repeat I-set PF07679.16 RJW67760.1 - 2.6e-06 27.4 0.0 5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW67760.1 - 4.7e-06 27.1 0.2 2.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RJW67760.1 - 4.7e-06 26.7 0.1 9.3e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RJW67760.1 - 2.7e-05 24.4 0.0 8.4e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 RJW67760.1 - 0.0022 17.5 1.0 0.015 14.8 0.8 2.0 1 1 1 2 2 2 1 Leucine-rich repeat LRRCT PF01463.24 RJW67760.1 - 0.0044 17.5 0.2 0.017 15.6 0.2 2.1 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Shisa PF13908.6 RJW67760.1 - 0.015 15.6 0.0 0.039 14.2 0.0 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator V-set PF07686.17 RJW67760.1 - 0.029 14.6 0.2 0.61 10.3 0.2 2.6 1 1 0 1 1 1 0 Immunoglobulin V-set domain LRR_6 PF13516.6 RJW67760.1 - 0.046 13.8 22.3 2.2 8.6 0.1 6.7 7 0 0 7 7 7 0 Leucine Rich repeat LRR_5 PF13306.6 RJW67760.1 - 0.074 13.0 0.0 8.3 6.4 0.0 2.4 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Pkinase PF00069.25 RJW67763.1 - 1.1e-15 57.8 0.0 1.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67763.1 - 0.00012 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF775 PF05603.12 RJW67765.1 - 2.7e-43 147.8 0.0 4.5e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) MeaB PF03308.16 RJW67767.1 - 6.6e-84 281.0 0.3 3.7e-74 249.1 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MINDY_DUB PF04424.13 RJW67767.1 - 4.8e-32 110.4 0.0 9.9e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase cobW PF02492.19 RJW67767.1 - 0.0018 17.9 0.2 0.65 9.6 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 RJW67767.1 - 0.02 15.4 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RJW67767.1 - 0.031 14.5 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RJW67767.1 - 0.041 14.3 0.6 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RJW67767.1 - 0.068 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 RJW67767.1 - 0.15 12.6 0.3 0.56 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 RJW67767.1 - 0.16 12.0 0.0 0.56 10.3 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF4558 PF15104.6 RJW67767.1 - 0.67 10.0 2.7 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) PP1_bind PF15276.6 RJW67768.1 - 0.093 13.1 0.1 0.18 12.1 0.0 1.5 2 0 0 2 2 2 0 Protein phosphatase 1 binding RVT_1 PF00078.27 RJW67769.1 - 1.1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LID PF17916.1 RJW67770.1 - 9.2e-18 63.6 1.7 1.9e-17 62.6 1.7 1.6 1 0 0 1 1 1 1 LIM interaction domain (LID) LIM_bind PF01803.16 RJW67770.1 - 6.1e-06 26.0 0.2 6.1e-06 26.0 0.2 2.1 3 0 0 3 3 3 1 LIM-domain binding protein FAD_binding_4 PF01565.23 RJW67770.1 - 0.0087 15.8 1.8 0.16 11.7 1.8 2.4 1 1 0 1 1 1 1 FAD binding domain Cadherin PF00028.17 RJW67771.1 - 5.6e-63 209.4 6.2 2.3e-15 56.8 0.1 9.5 8 2 0 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 RJW67771.1 - 3.4e-09 36.4 0.2 0.019 14.8 0.1 5.3 5 1 0 5 5 5 3 Cadherin-like Cadherin_3 PF16184.5 RJW67771.1 - 0.0077 16.2 15.5 2.5 8.1 0.0 6.7 7 1 0 7 7 7 2 Cadherin-like RET_CLD1 PF17756.1 RJW67771.1 - 0.016 15.5 0.0 0.96 9.7 0.0 3.7 5 0 0 5 5 5 0 RET Cadherin like domain 1 BatA PF07584.11 RJW67771.1 - 0.17 12.3 0.1 0.44 11.0 0.1 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal RRM_1 PF00076.22 RJW67774.1 - 0.00047 19.9 0.0 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RJW67774.1 - 0.028 14.5 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 BacteriocIIc_cy PF12173.8 RJW67776.1 - 0.084 13.1 0.5 0.17 12.1 0.5 1.4 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like ASC PF00858.24 RJW67777.1 - 6.1e-27 94.7 2.1 1.1e-26 93.8 2.1 1.4 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel NUDIX_5 PF16705.5 RJW67777.1 - 0.033 13.9 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT GHMP_kinases_N PF00288.26 RJW67778.1 - 6.6e-16 58.3 0.3 6.6e-16 58.3 0.3 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RJW67778.1 - 1.5e-12 47.7 0.0 3.9e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 RJW67778.1 - 6.7e-05 22.4 0.0 0.00018 21.0 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature ATP-synt_ab PF00006.25 RJW67779.1 - 1.4e-62 211.1 0.0 2e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 RJW67779.1 - 2e-21 76.3 0.9 4.2e-21 75.2 0.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 RJW67779.1 - 0.0085 16.0 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 RJW67779.1 - 0.039 13.1 0.7 0.062 12.5 0.2 1.6 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 RJW67779.1 - 0.066 12.5 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 RJW67779.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 RJW67779.1 - 0.084 13.2 0.1 0.27 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 RJW67779.1 - 0.087 13.2 0.5 0.26 11.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RJW67779.1 - 0.21 11.5 0.3 0.53 10.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.20 RJW67780.1 - 3.3e-27 95.6 2.5 1.3e-18 67.3 0.4 3.4 2 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 RJW67780.1 - 0.0041 16.6 2.7 2 7.9 0.0 3.4 3 1 1 4 4 4 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW67780.1 - 0.011 15.3 0.1 0.29 10.6 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain TniB PF05621.11 RJW67780.1 - 0.075 12.4 0.1 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 Bacterial TniB protein zf-HC5HC2H_2 PF13832.6 RJW67781.1 - 3.9e-24 84.9 1.0 3.9e-24 84.9 1.0 3.2 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RJW67781.1 - 2.8e-18 65.9 16.3 4e-16 59.0 0.4 3.9 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.29 RJW67781.1 - 2.1e-17 62.8 29.9 7.3e-09 35.4 5.7 4.3 4 0 0 4 4 4 3 PHD-finger PHD_2 PF13831.6 RJW67781.1 - 0.00024 20.6 6.2 0.00024 20.6 6.2 4.6 3 2 0 3 3 3 2 PHD-finger Prok-RING_1 PF14446.6 RJW67781.1 - 0.0069 16.3 23.1 0.041 13.8 0.7 4.3 4 0 0 4 4 4 3 Prokaryotic RING finger family 1 Mod_r PF07200.13 RJW67781.1 - 0.019 15.1 1.4 0.73 9.9 0.3 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ZapB PF06005.12 RJW67781.1 - 0.046 14.2 2.3 6.3 7.3 0.6 2.6 2 0 0 2 2 2 0 Cell division protein ZapB C1_1 PF00130.22 RJW67781.1 - 0.86 9.5 32.4 0.35 10.8 0.6 4.6 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 RJW67781.1 - 6.8 6.9 21.4 2.9 8.1 0.9 4.0 3 1 0 3 3 3 0 KIAA1045 RING finger Astro_capsid_p PF12226.8 RJW67781.1 - 8.5 5.4 12.0 14 4.7 12.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DENN PF02141.21 RJW67782.1 - 5.3e-32 111.3 5.0 1.7e-31 109.6 5.0 2.0 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 RJW67782.1 - 1.3e-20 73.8 1.0 5.6e-20 71.9 0.7 2.4 2 0 0 2 2 2 1 uDENN domain DnaJ PF00226.31 RJW67783.1 - 1e-16 60.8 2.8 2.2e-16 59.7 2.8 1.6 1 0 0 1 1 1 1 DnaJ domain FNIP_C PF14638.6 RJW67784.1 - 2.6e-14 53.3 0.0 1.8e-13 50.6 0.0 2.3 1 1 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_M PF14637.6 RJW67784.1 - 8.1e-10 39.1 0.0 4.6e-08 33.4 0.0 3.0 2 1 0 2 2 2 1 Folliculin-interacting protein middle domain Synaphin PF05835.12 RJW67785.1 - 1.4e-44 151.8 10.3 1.7e-44 151.6 10.3 1.0 1 0 0 1 1 1 1 Synaphin protein DUF2226 PF09987.9 RJW67785.1 - 0.016 14.6 2.2 0.027 13.8 2.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) OmpH PF03938.14 RJW67785.1 - 0.15 12.4 5.6 0.2 12.0 5.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SpecificRecomb PF10136.9 RJW67785.1 - 0.17 10.1 0.0 0.28 9.4 0.0 1.2 1 0 0 1 1 1 0 Site-specific recombinase DUF4407 PF14362.6 RJW67785.1 - 0.56 9.5 4.3 0.65 9.3 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) tRNA_bind_2 PF13725.6 RJW67785.1 - 3.7 7.2 7.7 0.47 10.1 2.8 1.7 2 0 0 2 2 2 0 Possible tRNA binding domain NUDIX_2 PF13869.6 RJW67786.1 - 7e-72 241.0 0.0 9e-72 240.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Methyltransf_11 PF08241.12 RJW67787.1 - 1.7e-12 47.8 0.0 2.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW67787.1 - 5.5e-10 39.8 0.0 8.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RJW67787.1 - 9.5e-09 35.9 0.0 1.4e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW67787.1 - 9.2e-07 28.8 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RJW67787.1 - 2.6e-05 23.7 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 RJW67787.1 - 0.015 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mon2_C PF16206.5 RJW67788.1 - 2.8e-125 419.3 4.9 3.8e-59 200.6 0.9 3.4 2 1 1 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 RJW67788.1 - 1.5e-08 34.4 0.2 2.3e-07 30.6 0.0 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) zf-C2H2 PF00096.26 RJW67789.1 - 8.2e-05 22.8 14.5 0.0071 16.8 1.5 4.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf_C2H2_10 PF18414.1 RJW67789.1 - 0.032 13.7 1.4 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-C2H2_4 PF13894.6 RJW67789.1 - 0.047 14.5 14.0 1.5 9.8 1.4 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RJW67789.1 - 0.074 12.7 1.7 0.32 10.7 0.1 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn_Tnp_IS1595 PF12760.7 RJW67789.1 - 0.94 9.5 9.1 0.88 9.6 3.6 2.8 3 0 0 3 3 3 0 Transposase zinc-ribbon domain C1_1 PF00130.22 RJW67789.1 - 1.2 9.1 9.0 1.1e+02 2.8 7.4 3.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 RJW67789.1 - 3.7 7.6 7.1 9 6.4 0.1 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid OrfB_Zn_ribbon PF07282.11 RJW67789.1 - 4.4 7.3 9.1 6.4 6.8 0.0 4.0 4 0 0 4 4 4 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 RJW67789.1 - 7.1 6.8 7.7 29 4.9 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain tRNA-synt_1b PF00579.25 RJW67791.1 - 1.6e-14 53.9 0.0 2.8e-14 53.1 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Tho2 PF11262.8 RJW67791.1 - 0.16 11.2 0.1 0.29 10.3 0.0 1.5 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 IQ PF00612.27 RJW67792.1 - 0.0002 20.9 0.5 0.00031 20.3 0.1 1.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif G-patch_2 PF12656.7 RJW67794.1 - 3.3e-11 43.1 0.1 7e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 G-patch domain KN17_SH3 PF18131.1 RJW67794.1 - 7.9e-05 22.7 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain KOW PF00467.29 RJW67794.1 - 0.002 18.0 0.4 0.012 15.5 0.8 2.1 2 0 0 2 2 2 1 KOW motif DUF4438 PF14505.6 RJW67794.1 - 0.064 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) Sec23_trunk PF04811.15 RJW67795.1 - 2.1e-57 194.5 0.0 3.4e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 RJW67795.1 - 1.4e-19 69.8 0.0 3.4e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RJW67795.1 - 1.8e-19 70.3 0.1 3.5e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 RJW67795.1 - 9.6e-16 57.6 3.1 2.2e-15 56.4 3.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 RJW67795.1 - 0.023 14.1 0.0 0.065 12.6 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF4509 PF14970.6 RJW67796.1 - 6.4e-07 29.5 0.5 2.9e-06 27.3 0.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4509) Ras PF00071.22 RJW67797.1 - 5.5e-16 58.6 0.0 1.1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW67797.1 - 5.2e-06 26.7 0.0 0.063 13.5 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RJW67797.1 - 1e-05 25.1 0.1 0.00015 21.3 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RJW67797.1 - 3.4e-05 23.9 0.0 7.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 RJW67797.1 - 0.0038 16.7 0.0 0.043 13.3 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family NOG1 PF06858.14 RJW67797.1 - 0.078 12.8 0.2 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1_Xtn PF16897.5 RJW67797.1 - 0.12 12.3 0.0 0.35 10.9 0.0 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ras PF00071.22 RJW67798.1 - 3.1e-43 147.2 1.9 6.4e-43 146.1 0.1 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 RJW67798.1 - 1.2e-29 103.0 0.2 3.1e-29 101.6 0.2 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW67798.1 - 1e-16 60.9 0.1 2.3e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW67798.1 - 2.9e-10 40.3 1.1 6.8e-10 39.0 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_8 PF13833.6 RJW67798.1 - 1.7e-06 27.7 0.4 1.3e-05 24.9 0.2 2.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 RJW67798.1 - 2.5e-06 27.8 1.2 2.5e-06 27.8 1.2 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW67798.1 - 1.5e-05 24.5 1.0 0.18 11.8 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RJW67798.1 - 4.7e-05 22.6 0.4 0.079 12.5 0.0 2.8 2 0 0 2 2 2 2 EF hand Gtr1_RagA PF04670.12 RJW67798.1 - 0.00018 21.0 0.0 0.00018 21.0 0.0 2.0 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 RJW67798.1 - 0.021 14.3 0.3 0.087 12.4 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Bacillus_HBL PF05791.11 RJW67798.1 - 0.029 14.2 9.2 0.053 13.3 9.2 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) GTP_EFTU PF00009.27 RJW67798.1 - 0.072 12.6 0.0 0.072 12.6 0.0 3.0 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain Baculo_PEP_C PF04513.12 RJW67798.1 - 3.4 7.7 11.2 2.2 8.3 0.5 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SMAP PF15477.6 RJW67798.1 - 3.4 8.7 10.2 3.9e+02 2.1 9.7 2.9 1 1 0 1 1 1 0 Small acidic protein family Peptidase_S46 PF10459.9 RJW67798.1 - 3.9 6.0 18.8 5.3 5.5 18.8 1.1 1 0 0 1 1 1 0 Peptidase S46 OmpH PF03938.14 RJW67798.1 - 7.3 6.9 36.2 0.19 12.1 14.3 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) RsgA_GTPase PF03193.16 RJW67798.1 - 7.6 6.4 10.1 1.3 8.9 0.0 3.4 4 0 0 4 4 4 0 RsgA GTPase CDC45 PF02724.14 RJW67799.1 - 3e-86 290.1 9.9 1.2e-52 179.2 4.0 3.1 1 1 2 3 3 3 3 CDC45-like protein Pkinase PF00069.25 RJW67801.1 - 1.6e-69 234.3 0.0 2.1e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW67801.1 - 7.6e-28 97.5 0.0 1.1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RJW67801.1 - 2.1e-05 24.0 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RJW67801.1 - 0.00052 19.4 0.0 0.00075 18.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RJW67801.1 - 0.016 15.1 0.5 2.3 8.1 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family MLVIN_C PF18697.1 RJW67801.1 - 0.063 13.4 0.5 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain SH3_1 PF00018.28 RJW67802.1 - 8.9e-45 150.1 1.5 1.5e-15 56.5 0.1 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 RJW67802.1 - 2.5e-41 139.3 1.8 4.4e-14 52.1 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 RJW67802.1 - 1.6e-32 110.9 0.0 4.8e-10 39.0 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.24 RJW67802.1 - 1.3e-17 63.6 0.0 3.1e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 RJW67802.1 - 8.8e-11 41.9 3.5 3.4e-05 24.0 0.2 3.4 3 0 0 3 3 3 3 Bacterial SH3 domain SH3_10 PF17902.1 RJW67802.1 - 4e-07 30.0 0.1 0.00047 20.2 0.0 3.5 3 0 0 3 3 3 1 SH3 domain hSH3 PF14603.6 RJW67802.1 - 3.1e-06 27.5 0.0 0.33 11.4 0.0 3.2 3 0 0 3 3 3 2 Helically-extended SH3 domain DUF4648 PF15505.6 RJW67802.1 - 0.11 13.4 0.0 18 6.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) SH2_2 PF14633.6 RJW67802.1 - 0.11 11.9 0.0 1.2 8.5 0.0 1.9 1 1 1 2 2 2 0 SH2 domain SH3_4 PF06347.13 RJW67802.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.6 3 0 0 3 3 3 0 Bacterial SH3 domain SH3_16 PF18348.1 RJW67802.1 - 0.24 11.2 1.2 3.6 7.5 0.1 2.5 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain HAT_KAT11 PF08214.11 RJW67804.1 - 1.9e-63 214.9 1.6 1.9e-63 214.9 1.6 2.2 2 1 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 RJW67804.1 - 6.8e-21 74.1 0.3 2e-20 72.6 0.3 1.9 1 0 0 1 1 1 1 Bromodomain zf-TAZ PF02135.16 RJW67804.1 - 5.4e-18 65.2 38.1 1.5e-13 51.0 14.7 4.5 4 0 0 4 4 3 2 TAZ zinc finger DUF902 PF06001.13 RJW67804.1 - 2.8e-17 62.9 6.7 9.6e-17 61.2 6.7 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) KIX PF02172.16 RJW67804.1 - 2.1e-12 47.1 0.7 5.1e-12 45.9 0.7 1.7 1 0 0 1 1 1 1 KIX domain ZZ PF00569.17 RJW67804.1 - 4.6e-08 32.8 6.1 4.6e-08 32.8 6.1 4.3 4 0 0 4 4 4 1 Zinc finger, ZZ type Peptidase_C58 PF03543.14 RJW67804.1 - 0.18 11.5 12.6 0.028 14.1 1.8 2.6 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen CDC45 PF02724.14 RJW67804.1 - 0.21 9.8 2.8 0.39 8.9 2.8 1.4 1 0 0 1 1 1 0 CDC45-like protein ATP11 PF06644.11 RJW67804.1 - 1.4 8.7 9.1 1.9 8.2 0.7 2.7 2 0 0 2 2 2 0 ATP11 protein DUF4611 PF15387.6 RJW67804.1 - 2.2 8.5 8.4 5.4 7.3 8.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF4168 PF13767.6 RJW67804.1 - 8.6 7.6 8.0 0.23 12.6 0.3 2.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4168) PcfK PF14058.6 RJW67804.1 - 9.8 6.5 11.1 4.2 7.6 3.4 2.7 2 0 0 2 2 2 0 PcfK-like protein Helicase_C PF00271.31 RJW67806.1 - 3.2e-15 56.4 0.0 6.5e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 RJW67806.1 - 1.8e-09 38.2 0.2 5.6e-09 36.6 0.2 1.9 1 0 0 1 1 1 1 RecQ zinc-binding NODP PF07684.12 RJW67806.1 - 0.056 13.6 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 NOTCH protein DEAD PF00270.29 RJW67806.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase CD20 PF04103.15 RJW67809.1 - 4.1e-07 30.2 6.6 1.2e-06 28.7 6.6 1.9 1 1 0 1 1 1 1 CD20-like family Claudin_2 PF13903.6 RJW67809.1 - 0.95 9.2 5.5 0.75 9.5 1.9 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction UPF0220 PF05255.11 RJW67811.1 - 1.6e-28 99.3 1.0 2e-28 99.0 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) TMEM43 PF07787.12 RJW67811.1 - 0.56 9.6 1.8 0.95 8.8 1.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 Ion_trans PF00520.31 RJW67812.1 - 3.5e-27 95.2 17.4 5.2e-27 94.6 17.4 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 RJW67812.1 - 1.8e-26 92.1 0.2 3.9e-26 91.0 0.2 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.12 RJW67812.1 - 1.1e-08 34.3 14.0 4.6e-06 25.6 4.4 2.1 2 0 0 2 2 2 2 Polycystin cation channel Ank_4 PF13637.6 RJW67812.1 - 2.5e-05 24.7 0.5 0.0058 17.2 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW67812.1 - 0.00043 20.8 1.0 0.22 12.2 0.8 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW67812.1 - 0.68 10.7 2.2 42 5.2 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat S-AdoMet_synt_N PF00438.20 RJW67813.1 - 0.056 14.1 0.1 0.12 13.0 0.1 1.6 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain HicB PF05534.12 RJW67813.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 HicB family Pup PF05639.11 RJW67813.1 - 4 8.4 7.3 17 6.4 0.1 3.6 4 0 0 4 4 4 0 Pup-like protein FERM_M PF00373.18 RJW67814.1 - 1.3e-13 51.4 0.1 2.1e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 RJW67814.1 - 2.9e-09 36.7 0.8 5.9e-09 35.8 0.3 1.8 2 0 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.10 RJW67814.1 - 1.2e-08 35.2 0.2 2.8e-08 34.0 0.2 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DUF4954 PF16314.5 RJW67814.1 - 0.1 10.7 0.2 0.15 10.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) THAP PF05485.12 RJW67815.1 - 1.6e-08 35.4 0.0 5.7e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 THAP domain 2-Hacid_dh_C PF02826.19 RJW67815.1 - 0.0025 17.2 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Kunitz_BPTI PF00014.23 RJW67816.1 - 4.2e-15 55.7 5.9 7.3e-15 55.0 5.9 1.4 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain WD40 PF00400.32 RJW67817.1 - 2.9e-20 72.2 19.3 0.029 15.3 0.3 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW67817.1 - 2e-07 31.2 0.0 0.43 10.9 0.0 4.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain SH3_1 PF00018.28 RJW67818.1 - 1.3e-37 127.2 0.4 3.9e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 RJW67818.1 - 1.5e-34 117.6 1.2 2.5e-13 49.7 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 RJW67818.1 - 1.2e-29 101.7 0.1 1.7e-10 40.4 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.24 RJW67818.1 - 1e-11 44.8 0.2 6.4e-11 42.2 0.0 2.4 3 0 0 3 3 3 1 SH2 domain SH3_3 PF08239.11 RJW67818.1 - 4.6e-10 39.6 0.9 3e-05 24.2 0.2 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_16 PF18348.1 RJW67818.1 - 5.9e-05 22.8 0.3 0.77 9.6 0.0 3.4 3 0 0 3 3 3 2 Bacterial dipeptidyl-peptidase Sh3 domain SH3_4 PF06347.13 RJW67818.1 - 6.6e-05 22.6 0.2 0.019 14.8 0.1 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_10 PF17902.1 RJW67818.1 - 0.00022 21.2 0.1 0.0035 17.4 0.0 2.6 3 0 0 3 3 3 1 SH3 domain hSH3 PF14603.6 RJW67818.1 - 0.011 16.2 0.0 4.3 7.8 0.0 3.0 3 0 0 3 3 3 0 Helically-extended SH3 domain SH2_2 PF14633.6 RJW67818.1 - 0.15 11.5 0.0 2.8 7.3 0.0 2.2 1 1 1 2 2 2 0 SH2 domain dCMP_cyt_deam_1 PF00383.23 RJW67820.1 - 0.22 11.4 1.6 7.9 6.4 0.3 2.2 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region TLE_N PF03920.15 RJW67822.1 - 9.2e-54 181.0 4.4 1.7e-53 180.1 4.4 1.4 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain Ribosomal_S18 PF01084.20 RJW67822.1 - 0.076 13.2 0.1 0.23 11.7 0.1 1.9 1 0 0 1 1 1 0 Ribosomal protein S18 7tm_1 PF00001.21 RJW67824.1 - 1.5e-67 227.7 8.3 2.9e-67 226.8 8.3 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW67824.1 - 0.0015 17.9 12.4 0.091 12.1 0.5 3.6 4 0 0 4 4 4 3 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RJW67824.1 - 0.0046 16.6 1.8 0.0046 16.6 1.8 2.8 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RJW67824.1 - 0.022 14.1 12.7 0.011 15.0 6.6 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 RJW67824.1 - 0.8 9.0 9.9 0.046 13.1 1.5 2.6 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF4199 PF13858.6 RJW67824.1 - 4.2 7.8 8.8 0.13 12.6 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Ig_3 PF13927.6 RJW67825.1 - 3.1e-18 66.1 9.0 3.2e-08 34.0 0.1 7.0 6 1 0 6 6 6 4 Immunoglobulin domain I-set PF07679.16 RJW67825.1 - 4.3e-10 39.5 0.1 0.00043 20.3 0.0 6.2 7 0 0 7 7 7 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 RJW67825.1 - 1.1e-08 35.0 4.4 0.0035 17.4 0.8 6.3 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 RJW67825.1 - 1.6e-08 34.6 5.4 0.00058 20.0 0.1 6.3 7 1 0 7 7 7 2 Immunoglobulin domain Ig_2 PF13895.6 RJW67825.1 - 7.1e-07 29.5 13.5 5.2e-06 26.7 0.1 6.4 8 1 1 9 9 9 1 Immunoglobulin domain C1-set PF07654.15 RJW67825.1 - 0.002 18.5 1.2 55 4.2 0.0 5.3 5 0 0 5 5 5 0 Immunoglobulin C1-set domain V-set PF07686.17 RJW67825.1 - 0.0022 18.2 2.4 0.65 10.2 0.3 4.9 4 1 0 4 4 4 1 Immunoglobulin V-set domain Herpes_gE PF02480.16 RJW67825.1 - 0.0076 15.1 0.0 0.017 13.9 0.0 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E zf-CpG_bind_C PF12269.8 RJW67826.1 - 4.7e-65 219.6 4.2 5.4e-65 219.5 4.2 1.0 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain CLIP_SPH_mas PF18398.1 RJW67826.1 - 2.8 8.4 8.6 0.77 10.2 0.5 2.8 3 0 0 3 3 3 0 Clip-domain serine protease homolog masquerade zf-TAZ PF02135.16 RJW67826.1 - 7.3 7.1 11.0 1.3e+02 3.2 11.0 2.3 1 1 0 1 1 1 0 TAZ zinc finger RYDR_ITPR PF01365.21 RJW67829.1 - 3.4e-39 134.4 17.4 1.4e-35 122.6 0.1 3.9 5 0 0 5 5 5 2 RIH domain RIH_assoc PF08454.11 RJW67829.1 - 4.9e-36 122.6 6.4 9.2e-36 121.7 0.0 4.3 4 1 0 4 4 4 1 RyR and IP3R Homology associated Ion_trans PF00520.31 RJW67829.1 - 6.3e-16 58.3 2.4 1.7e-15 56.9 2.4 1.8 1 0 0 1 1 1 1 Ion transport protein Nup35_RRM PF05172.13 RJW67829.1 - 0.033 14.2 0.0 0.34 10.9 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF2897 PF11446.8 RJW67829.1 - 0.18 11.7 0.6 0.42 10.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Choline_transpo PF04515.12 RJW67830.1 - 7.4e-14 51.7 9.0 9.2e-14 51.4 9.0 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter rve PF00665.26 RJW67831.1 - 3.6e-16 59.4 0.0 6.4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW67831.1 - 4.4e-15 55.5 0.1 8.8e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 RJW67831.1 - 2.3e-05 24.1 0.0 4.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RJW67831.1 - 4.5e-05 23.6 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-nanos PF05741.13 RJW67832.1 - 8.9e-25 86.7 4.2 1.8e-24 85.7 4.2 1.5 1 0 0 1 1 1 1 Nanos RNA binding domain zf-C2H2_2 PF12756.7 RJW67832.1 - 0.067 13.5 3.6 0.35 11.2 1.6 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) ketoacyl-synt PF00109.26 RJW67833.1 - 1.7e-45 155.6 4.2 8.6e-45 153.3 1.3 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 RJW67833.1 - 1.5e-26 92.7 0.4 3.6e-26 91.5 0.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 RJW67833.1 - 0.00011 21.6 0.1 0.00027 20.4 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 RJW67833.1 - 0.053 14.0 0.1 0.14 12.6 0.1 1.8 1 1 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension IKI3 PF04762.12 RJW67834.1 - 1.6e-140 470.0 0.0 3e-82 277.1 0.0 3.2 3 0 0 3 3 3 3 IKI3 family TPR_16 PF13432.6 RJW67834.1 - 0.097 13.3 2.8 1.3 9.7 1.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat FNIP_C PF14638.6 RJW67835.1 - 0.076 12.6 0.0 0.09 12.4 0.0 1.0 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus Nuc_sug_transp PF04142.15 RJW67836.1 - 1.1e-90 304.0 15.2 1.3e-90 303.7 15.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RJW67836.1 - 1.8e-07 31.4 32.7 3.5e-05 24.0 11.6 2.6 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 RJW67836.1 - 5.3e-05 22.6 7.0 5.3e-05 22.6 7.0 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 RJW67836.1 - 0.00066 19.1 14.1 0.0028 17.0 3.3 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 RJW67836.1 - 0.039 13.1 18.0 0.024 13.9 2.6 2.6 1 1 1 2 2 2 0 UAA transporter family G-alpha PF00503.20 RJW67837.1 - 3.1e-89 299.6 1.0 3.7e-89 299.4 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RJW67837.1 - 1.3e-12 47.5 0.2 1.3e-11 44.3 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family 14-3-3 PF00244.20 RJW67838.1 - 5.7e-47 160.1 2.3 7e-47 159.8 2.3 1.1 1 0 0 1 1 1 1 14-3-3 protein Hemerythrin PF01814.23 RJW67840.1 - 0.13 12.9 0.0 0.23 12.1 0.0 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain RVT_1 PF00078.27 RJW67841.1 - 7.8e-46 156.4 0.3 1.7e-45 155.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_4 PF12799.7 RJW67841.1 - 2.2e-44 148.7 102.4 1.9e-07 31.3 3.9 15.8 11 4 5 17 17 17 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW67841.1 - 3.1e-37 127.7 39.1 1.5e-11 44.1 0.1 10.0 5 4 4 9 9 9 8 Leucine-rich repeat LRR_8 PF13855.6 RJW67841.1 - 1.3e-32 111.3 81.8 1.5e-10 40.7 1.6 10.7 6 4 5 12 12 12 11 Leucine rich repeat Exo_endo_phos_2 PF14529.6 RJW67841.1 - 2.7e-11 43.4 0.0 1.2e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase IFRD PF05004.13 RJW67843.1 - 9.5e-47 159.6 0.0 1.3e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 RJW67843.1 - 2.7e-12 47.1 1.5 6.5e-12 45.8 1.5 1.7 1 0 0 1 1 1 1 Interferon-related protein conserved region 14-3-3 PF00244.20 RJW67846.1 - 1.3e-84 283.2 3.1 1.5e-84 283.0 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein UBA PF00627.31 RJW67847.1 - 0.12 12.4 0.5 0.22 11.5 0.1 1.7 2 0 0 2 2 2 0 UBA/TS-N domain ZZ PF00569.17 RJW67847.1 - 0.64 9.9 7.3 1.1 9.1 7.3 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Globin PF00042.22 RJW67848.1 - 8e-14 52.1 0.1 1.2e-13 51.5 0.0 1.4 2 0 0 2 2 2 1 Globin DUF2642 PF10842.8 RJW67849.1 - 0.18 11.7 0.0 0.68 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Cadherin PF00028.17 RJW67850.1 - 1.7e-60 201.4 11.3 8.2e-14 51.8 0.1 9.2 8 2 0 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 RJW67850.1 - 2e-10 40.4 0.1 0.0096 15.7 0.0 5.7 6 0 0 6 6 6 3 Cadherin-like RET_CLD1 PF17756.1 RJW67850.1 - 7.4e-05 23.0 0.1 0.1 12.9 0.0 4.4 5 0 0 5 5 5 1 RET Cadherin like domain 1 DUF2428 PF10350.9 RJW67851.1 - 1.7e-51 175.1 0.0 7.6e-51 173.0 0.0 2.1 1 1 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) zf-met PF12874.7 RJW67853.1 - 0.047 14.1 0.8 0.047 14.1 0.8 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 RJW67853.1 - 0.32 11.9 13.5 0.37 11.8 1.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger IBR PF01485.21 RJW67853.1 - 7.6 6.8 15.7 7.1 6.9 2.7 3.2 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain LSDAT_euk PF18139.1 RJW67854.1 - 1e-50 172.6 0.0 5.2e-46 157.2 0.0 2.2 2 0 0 2 2 2 2 SLOG in TRPM LSDAT_prok PF18171.1 RJW67854.1 - 2e-15 56.6 0.0 5.1e-15 55.3 0.0 1.6 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 RJW67854.1 - 2e-13 50.2 14.4 4.2e-13 49.1 14.4 1.6 1 0 0 1 1 1 1 Ion transport protein FBD PF08387.10 RJW67854.1 - 0.15 12.0 0.4 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 FBD Cpn60_TCP1 PF00118.24 RJW67855.1 - 2.3e-156 521.3 0.9 2.8e-156 521.0 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FlhD PF05247.13 RJW67855.1 - 0.082 13.2 0.4 6.2 7.2 0.0 2.8 3 0 0 3 3 3 0 Flagellar transcriptional activator (FlhD) COesterase PF00135.28 RJW67856.1 - 3.8e-120 402.2 0.0 8.7e-118 394.4 0.0 2.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RJW67856.1 - 3.6e-05 23.7 2.0 0.00019 21.4 2.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold AhpC-TSA PF00578.21 RJW67857.1 - 5.8e-38 129.6 0.0 8.9e-38 129.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RJW67857.1 - 8.6e-15 54.7 0.0 1.1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RJW67857.1 - 1.6e-13 50.2 0.0 2.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Mpp10 PF04006.12 RJW67859.1 - 1.7e-47 162.2 11.6 2.3e-47 161.8 11.6 1.0 1 0 0 1 1 1 1 Mpp10 protein PGM_PMM_I PF02878.16 RJW67860.1 - 2.1e-28 98.8 0.0 3.5e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 RJW67860.1 - 2.1e-26 92.4 0.0 6.3e-26 90.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 RJW67860.1 - 1.9e-10 41.3 0.0 7.6e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 RJW67860.1 - 3.2e-05 24.0 0.0 0.0001 22.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RED_N PF07808.13 RJW67862.1 - 3.7e-86 288.5 4.8 8.7e-86 287.3 4.8 1.5 1 0 0 1 1 1 1 RED-like protein N-terminal region RED_C PF07807.11 RJW67862.1 - 3e-53 179.1 3.3 3e-53 179.1 3.3 2.6 3 0 0 3 3 3 1 RED-like protein C-terminal region Lsm_interact PF05391.11 RJW67862.1 - 0.0036 16.7 1.1 0.0036 16.7 1.1 2.0 2 0 0 2 2 2 1 Lsm interaction motif GTP_EFTU PF00009.27 RJW67863.1 - 1.3e-42 145.5 0.0 2.2e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 RJW67863.1 - 1.1e-09 38.2 0.0 2.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 RJW67863.1 - 1.2e-06 28.5 0.0 2.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 RJW67863.1 - 0.0036 17.1 0.0 0.0083 15.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV SRPRB PF09439.10 RJW67863.1 - 0.0085 15.5 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Myotub-related PF06602.14 RJW67865.1 - 1.4e-118 395.9 0.0 2e-118 395.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 RJW67865.1 - 0.0031 17.3 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RJW67865.1 - 0.0039 17.2 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family FYVE_2 PF02318.16 RJW67865.1 - 0.0058 16.8 2.6 0.0058 16.8 2.6 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger Y_phosphatase PF00102.27 RJW67865.1 - 0.021 14.4 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase IBR PF01485.21 RJW67865.1 - 0.1 12.8 1.6 0.34 11.2 1.6 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE PF01363.21 RJW67865.1 - 1.9 8.7 15.5 0.089 12.9 7.7 2.5 2 1 0 2 2 2 0 FYVE zinc finger SDF PF00375.18 RJW67866.1 - 8.9e-48 163.2 26.8 1.1e-47 162.9 26.8 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family TMEM132D_C PF15706.5 RJW67866.1 - 0.031 14.1 1.7 0.086 12.6 1.7 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF2157 PF09925.9 RJW67866.1 - 0.81 9.5 8.6 1.4 8.7 7.2 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF417 PF04224.12 RJW67866.1 - 1.7 8.1 8.8 0.12 12.0 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF417 DUF4718 PF15842.5 RJW67866.1 - 2 8.2 3.6 4.2 7.1 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) PK PF00224.21 RJW67867.1 - 8e-88 294.6 0.0 9.8e-88 294.3 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RJW67867.1 - 3.4e-27 95.0 0.3 1.3e-26 93.1 0.2 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain EF-hand_7 PF13499.6 RJW67870.1 - 2.6e-12 47.0 0.5 6.2e-06 26.6 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW67870.1 - 2.1e-09 36.5 0.1 0.0052 16.6 0.0 3.6 2 1 2 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 RJW67870.1 - 1.2e-08 34.6 2.9 2.7e-06 27.1 0.2 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW67870.1 - 1.6e-06 27.3 1.3 0.014 14.9 0.0 4.9 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.6 RJW67870.1 - 3.2e-06 27.4 0.2 0.097 13.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 RJW67870.1 - 0.014 15.4 1.7 0.022 14.9 0.4 2.0 2 1 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 RJW67870.1 - 0.019 15.8 0.1 0.04 14.8 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain EF-hand_4 PF12763.7 RJW67870.1 - 0.042 13.8 0.1 0.27 11.2 0.0 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 RJW67870.1 - 0.13 11.8 2.2 9 6.0 0.0 3.7 4 1 0 4 4 4 0 EF hand PMBR PF09373.10 RJW67870.1 - 0.14 12.3 0.1 12 6.3 0.0 3.1 3 0 0 3 3 3 0 Pseudomurein-binding repeat dsrm PF00035.26 RJW67872.1 - 6.7e-19 68.4 3.7 2.6e-08 34.4 0.4 3.5 3 1 0 3 3 3 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 RJW67872.1 - 8.4e-07 29.2 9.3 0.045 14.0 4.4 5.0 3 2 1 4 4 4 3 double strand RNA binding domain from DEAD END PROTEIN 1 DUF4517 PF15006.6 RJW67874.1 - 6.1e-28 97.9 0.0 1e-27 97.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4517) MBD_C PF14048.6 RJW67875.1 - 6.9e-29 100.4 0.2 1.3e-28 99.6 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBD PF01429.19 RJW67875.1 - 1.2e-12 47.3 0.2 2.8e-12 46.2 0.1 1.7 1 1 0 1 1 1 1 Methyl-CpG binding domain MBDa PF16564.5 RJW67875.1 - 4.4e-05 23.6 0.3 0.00018 21.6 0.1 2.2 2 0 0 2 2 2 1 p55-binding region of Methyl-CpG-binding domain proteins MBD Orbi_VP1 PF05788.12 RJW67876.1 - 0.036 11.7 0.0 0.049 11.2 0.0 1.1 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) Mx_ML PF17536.2 RJW67878.1 - 0.15 11.8 0.6 0.23 11.2 0.6 1.2 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal Ig_3 PF13927.6 RJW67879.1 - 1.6e-09 38.2 1.2 2.3e-05 24.9 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RJW67879.1 - 1.8e-05 24.8 0.8 0.0042 17.2 0.1 2.8 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RJW67879.1 - 0.00022 21.2 0.0 0.029 14.4 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW67879.1 - 0.00066 20.0 5.7 0.0065 16.8 0.5 3.3 2 2 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 RJW67879.1 - 0.0029 17.8 0.7 0.01 16.0 0.2 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 RJW67879.1 - 0.0045 17.0 0.5 0.019 15.0 0.4 2.0 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 RJW67879.1 - 0.064 13.7 0.3 0.4 11.1 0.3 2.3 1 1 0 1 1 1 0 Immunoglobulin C1-set domain Trm112p PF03966.16 RJW67879.1 - 0.083 13.5 0.1 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 Trm112p-like protein SKG6 PF08693.10 RJW67879.1 - 0.35 10.3 2.7 0.87 9.1 2.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LicD PF04991.13 RJW67880.1 - 0.017 15.3 0.1 0.25 11.4 0.0 2.1 1 1 1 2 2 2 0 LicD family Oxidored_q6 PF01058.22 RJW67881.1 - 0.22 11.4 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Homeodomain PF00046.29 RJW67882.1 - 1.3e-22 79.4 4.1 4.5e-22 77.6 4.1 1.9 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW67882.1 - 0.072 13.0 0.6 0.27 11.2 0.6 2.0 1 0 0 1 1 1 0 Homeobox KN domain MMM1 PF10296.9 RJW67882.1 - 0.15 11.1 2.4 0.17 10.9 0.5 1.9 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 WD40 PF00400.32 RJW67883.1 - 0.0023 18.7 33.1 0.0055 17.5 0.8 10.7 12 0 0 12 12 12 2 WD domain, G-beta repeat DUF4427 PF14468.6 RJW67883.1 - 0.18 11.9 0.1 0.98 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4427) Ribosomal_L36e PF01158.18 RJW67884.1 - 1.3e-35 121.5 9.4 1.4e-35 121.4 9.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Nop14 PF04147.12 RJW67886.1 - 0.00011 20.7 15.7 0.00011 20.7 15.7 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 RJW67886.1 - 0.069 11.4 16.4 0.08 11.2 16.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 RJW67886.1 - 0.1 12.4 10.0 0.15 11.8 10.0 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 RJW67886.1 - 0.66 8.0 48.5 0.85 7.7 48.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi CNDH2_C PF16858.5 RJW67886.1 - 0.76 9.6 7.7 0.9 9.4 7.7 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Mpp10 PF04006.12 RJW67886.1 - 0.98 7.8 16.7 1.2 7.5 16.7 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RJW67886.1 - 1.1 8.6 25.1 1.3 8.4 25.1 1.2 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 RJW67886.1 - 1.3 8.4 17.5 1.8 7.9 17.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 RJW67886.1 - 2.5 7.4 43.3 1.2 8.4 39.9 1.9 1 1 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 RJW67886.1 - 3.9 7.0 21.2 6 6.4 21.2 1.4 1 0 0 1 1 1 0 PPP4R2 Cnd2 PF05786.14 RJW67886.1 - 6.8 5.2 19.5 7.4 5.1 19.5 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 RRN3 PF05327.11 RJW67886.1 - 8.1 4.9 27.1 9.9 4.6 27.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 RJW67886.1 - 8.4 5.6 21.6 10 5.4 21.6 1.1 1 0 0 1 1 1 0 BUD22 zinc_ribbon_4 PF13717.6 RJW67887.1 - 0.017 15.0 0.1 0.052 13.5 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain RNase_H PF00075.24 RJW67889.1 - 4.3e-20 72.4 0.0 5.6e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 RJW67889.1 - 0.1 12.4 0.0 6.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase-like ACT_5 PF13710.6 RJW67889.1 - 0.19 11.6 0.3 0.37 10.6 0.3 1.5 1 0 0 1 1 1 0 ACT domain RA PF00788.23 RJW67890.1 - 1.8e-07 31.7 0.2 4.7e-07 30.3 0.2 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 RJW67890.1 - 5.1e-06 26.9 0.0 1.6e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 PH domain Alpha_Helical PF18489.1 RJW67894.1 - 0.088 13.0 1.2 1.9 8.7 0.1 2.8 3 0 0 3 3 3 0 Alpha helical domain Band_7_C PF16200.5 RJW67894.1 - 0.12 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of band_7 LAG1-DNAbind PF09271.11 RJW67896.1 - 3e-49 167.5 0.0 1.1e-48 165.7 0.0 2.0 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 RJW67896.1 - 2.5e-25 89.5 0.1 5.1e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain PalH PF08733.10 RJW67898.1 - 0.0052 15.8 0.0 0.0052 15.8 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 TMEM100 PF16311.5 RJW67898.1 - 0.008 15.8 4.5 0.012 15.2 4.5 1.2 1 0 0 1 1 1 1 Transmembrane protein 100 MgtE PF01769.16 RJW67898.1 - 0.08 13.3 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Divalent cation transporter DUF3611 PF12263.8 RJW67898.1 - 0.63 9.9 3.3 0.9 9.4 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) ESPR PF13018.6 RJW67898.1 - 2.7 7.9 4.6 15 5.5 0.2 2.5 2 0 0 2 2 2 0 Extended Signal Peptide of Type V secretion system Retinin_C PF04527.12 RJW67902.1 - 0.1 12.9 0.8 0.16 12.3 0.1 1.7 2 0 0 2 2 2 0 Drosophila Retinin like protein DUF728 PF05304.12 RJW67903.1 - 0.041 13.7 0.6 0.071 13.0 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF728) Integrase_H2C2 PF17921.1 RJW67904.1 - 3.2e-05 23.9 0.1 0.00026 21.1 0.0 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain DUF4187 PF13821.6 RJW67905.1 - 1.5e-15 56.7 0.6 4e-15 55.3 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF2052 PF09747.9 RJW67905.1 - 2.4e-13 50.7 6.1 6.1e-10 39.6 0.2 4.7 3 2 1 4 4 4 2 Coiled-coil domain containing protein (DUF2052) G-patch PF01585.23 RJW67905.1 - 7.1e-13 48.2 1.7 1.4e-12 47.3 1.7 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RJW67905.1 - 0.0011 19.0 0.8 0.0011 19.0 0.8 2.2 2 0 0 2 2 2 1 G-patch domain Toxin_37 PF11415.8 RJW67908.1 - 0.5 10.2 3.9 0.31 10.9 1.6 1.9 2 0 0 2 2 2 0 Antifungal peptide termicin SPT6_acidic PF14632.6 RJW67909.1 - 6.5e-08 33.1 23.1 6.5e-08 33.1 23.1 1.7 1 1 1 2 2 2 1 Acidic N-terminal SPT6 Pox_Ag35 PF03286.14 RJW67909.1 - 0.031 14.1 5.7 0.049 13.4 5.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein zf-C3H2C3 PF17122.5 RJW67910.1 - 0.0029 17.6 2.2 0.014 15.4 2.2 2.3 1 0 0 1 1 1 1 Zinc-finger SWIM PF04434.17 RJW67910.1 - 0.0078 15.9 1.8 0.023 14.4 1.8 1.8 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.9 RJW67910.1 - 0.0092 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Bunya_G1 PF03557.15 RJW67911.1 - 0.079 10.9 0.0 0.11 10.5 0.0 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 Eclosion PF04736.12 RJW67911.1 - 0.12 12.1 0.8 0.2 11.4 0.8 1.3 1 0 0 1 1 1 0 Eclosion hormone DUF1560 PF07597.11 RJW67914.1 - 0.066 13.2 0.4 0.22 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1560) RPN7 PF10602.9 RJW67916.1 - 1.1e-56 191.3 0.3 1.7e-56 190.7 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 RJW67916.1 - 9.9e-14 51.7 0.5 7.8e-13 48.9 0.0 2.8 4 0 0 4 4 4 1 PCI domain eIF3_N PF09440.10 RJW67916.1 - 0.0018 18.7 3.0 0.0041 17.6 3.0 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain DUF4795 PF16043.5 RJW67916.1 - 0.0091 15.6 2.7 0.072 12.7 1.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) TTL PF03133.15 RJW67918.1 - 5e-79 265.5 1.7 9.5e-79 264.6 1.7 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RJW67918.1 - 3.7e-06 26.4 0.2 0.0045 16.3 0.0 2.8 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RJW67918.1 - 8.4e-05 22.0 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 RJW67918.1 - 0.0036 17.4 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Ribosomal_L6 PF00347.23 RJW67920.1 - 2.8e-23 82.4 3.3 1.2e-16 61.1 0.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Sulfate_transp PF00916.20 RJW67925.1 - 5.1e-79 265.8 19.7 5.8e-79 265.6 19.7 1.0 1 0 0 1 1 1 1 Sulfate permease family PB1-F2 PF11986.8 RJW67927.1 - 0.015 15.5 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 Influenza A Proapoptotic protein RRM_1 PF00076.22 RJW67928.1 - 1.9e-18 66.1 0.3 2.9e-13 49.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 RJW67928.1 - 0.022 15.0 0.0 11 6.2 0.0 3.2 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter NosL PF05573.12 RJW67928.1 - 0.079 13.3 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 NosL TPR_19 PF14559.6 RJW67929.1 - 7.5e-06 26.4 4.4 0.35 11.4 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW67929.1 - 0.017 15.3 1.9 0.65 10.3 0.2 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RJW67929.1 - 0.4 11.2 6.4 16 6.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 RJW67929.1 - 1.3 9.9 4.5 45 5.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2HE PF16278.5 RJW67931.1 - 0.013 15.9 6.2 2.1 8.9 0.0 3.9 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 RJW67931.1 - 0.017 15.6 0.4 0.017 15.6 0.4 4.8 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW67931.1 - 0.035 15.0 0.2 0.035 15.0 0.2 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.11 RJW67931.1 - 2.9 7.9 10.5 0.2 11.6 2.7 3.2 3 1 0 3 3 3 0 Putative transposase DNA-binding domain U3snoRNP10 PF12397.8 RJW67934.1 - 0.00015 22.1 0.1 0.0009 19.6 0.1 2.4 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 10 Innexin PF00876.18 RJW67936.1 - 8.7e-103 344.3 4.7 1e-102 344.1 4.7 1.0 1 0 0 1 1 1 1 Innexin TssO PF17561.2 RJW67936.1 - 0.29 11.2 0.7 5.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssO LPG_synthase_TM PF03706.13 RJW67936.1 - 3.7 7.0 6.4 0.26 10.8 0.4 2.1 4 0 0 4 4 4 0 Lysylphosphatidylglycerol synthase TM region DUF1673 PF07895.11 RJW67940.1 - 9.3 5.9 8.4 2.5 7.7 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Laminin_N PF00055.17 RJW67941.1 - 4.3e-76 255.6 0.6 4.3e-76 255.6 0.6 3.2 4 0 0 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 RJW67941.1 - 1.2e-75 249.5 235.1 1.6e-11 44.2 12.6 13.5 12 2 1 13 13 13 11 Laminin EGF domain F5_F8_type_C PF00754.25 RJW67941.1 - 0.16 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 F5/8 type C domain ZZ PF00569.17 RJW67942.1 - 0.00011 21.9 4.2 0.00021 21.0 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF2719 PF10891.8 RJW67942.1 - 0.0076 16.1 2.9 1.6 8.7 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF2719) zf-UBR PF02207.20 RJW67942.1 - 0.0099 16.0 0.8 0.023 14.8 0.8 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) WcbI PF18588.1 RJW67942.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI HTH_46 PF15977.5 RJW67943.1 - 0.025 14.6 0.2 0.074 13.1 0.2 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding Tropomyosin PF00261.20 RJW67943.1 - 0.029 13.8 0.5 0.058 12.8 0.5 1.4 1 0 0 1 1 1 0 Tropomyosin Arm PF00514.23 RJW67943.1 - 0.061 13.4 1.7 5.3 7.2 0.2 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Limkain-b1 PF11608.8 RJW67943.1 - 0.076 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Limkain b1 Plasmid_RAQPRD PF09686.10 RJW67943.1 - 0.13 12.4 1.8 4.2 7.6 0.8 2.8 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) V-ATPase_H_N PF03224.14 RJW67943.1 - 0.14 11.5 1.9 0.29 10.4 0.2 2.2 2 0 0 2 2 2 0 V-ATPase subunit H Pyridoxal_deC PF00282.19 RJW67945.1 - 4.2e-147 489.8 0.0 7.8e-147 488.9 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 RJW67945.1 - 0.0019 17.0 0.0 0.0032 16.2 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 RJW67945.1 - 0.0048 16.2 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase RVT_1 PF00078.27 RJW67946.1 - 3.4e-11 43.1 0.0 4.3e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Adeno_terminal PF02459.15 RJW67948.1 - 0.12 10.8 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Rdx PF10262.9 RJW67949.1 - 0.092 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Rdx family CutA1 PF03091.15 RJW67950.1 - 6.3e-39 131.8 0.7 8.1e-39 131.5 0.7 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DUF3959 PF13105.6 RJW67950.1 - 0.022 14.3 0.1 0.026 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DENN PF02141.21 RJW67951.1 - 2.5e-19 70.0 0.1 2.5e-19 70.0 0.1 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 RJW67951.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 dDENN domain zf-CCCH PF00642.24 RJW67952.1 - 1.4e-08 34.4 14.4 3.8e-07 29.8 6.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RJW67952.1 - 0.0035 17.4 5.5 0.0035 17.4 5.5 2.3 2 0 0 2 2 2 1 Zinc finger domain Lustrin_cystein PF14625.6 RJW67952.1 - 2.4 8.6 5.6 2.4 8.6 0.7 2.9 2 1 1 3 3 3 0 Lustrin, cysteine-rich repeated domain zf-CCCH_4 PF18044.1 RJW67952.1 - 9.4 6.2 12.2 0.31 10.9 4.6 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger zf-RING_2 PF13639.6 RJW67954.1 - 4.8e-13 49.2 9.1 8.6e-13 48.4 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RJW67954.1 - 1e-08 34.9 11.6 1.8e-08 34.1 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RJW67954.1 - 3.4e-08 33.1 6.3 7e-08 32.1 6.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 RJW67954.1 - 2.6e-07 30.4 5.6 4.5e-07 29.6 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW67954.1 - 2.2e-06 27.8 10.2 7e-06 26.2 10.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RJW67954.1 - 1.4e-05 25.0 6.0 1.5e-05 24.9 4.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RJW67954.1 - 4.1e-05 23.5 2.7 9.3e-05 22.4 2.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RJW67954.1 - 8.9e-05 22.3 7.4 0.00017 21.3 7.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RJW67954.1 - 9.3e-05 22.0 6.9 0.00019 21.0 6.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 RJW67954.1 - 0.00021 21.1 9.7 0.00037 20.3 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW67954.1 - 0.00072 19.5 8.3 0.0012 18.7 8.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-HC5HC2H_2 PF13832.6 RJW67954.1 - 0.0021 18.2 4.5 0.0083 16.3 5.0 1.7 1 1 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RJW67954.1 - 0.0028 17.9 4.3 0.013 15.7 4.7 1.8 1 1 1 2 2 2 1 PHD-like zinc-binding domain zinc_ribbon_16 PF17034.5 RJW67954.1 - 0.0044 17.2 2.7 0.0079 16.4 2.7 1.5 1 1 0 1 1 1 1 Zinc-ribbon like family zf-C3H2C3 PF17122.5 RJW67954.1 - 0.017 15.1 4.8 0.046 13.8 4.8 1.7 1 1 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 RJW67954.1 - 0.04 14.2 7.3 0.072 13.4 7.3 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 RJW67954.1 - 0.24 11.6 8.5 4.3 7.6 8.5 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 RJW67954.1 - 0.33 10.8 2.6 0.75 9.7 2.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 RJW67954.1 - 0.71 9.8 5.6 3.1 7.8 3.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 RJW67954.1 - 1.8 8.4 6.3 7.4 6.5 6.4 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Vps39_2 PF10367.9 RJW67954.1 - 2 8.9 6.8 4.3 7.8 2.3 2.9 4 1 0 4 4 2 0 Vacuolar sorting protein 39 domain 2 Med4 PF10018.9 RJW67955.1 - 1.8e-23 83.2 0.2 2.7e-23 82.7 0.2 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Ion_trans PF00520.31 RJW67957.1 - 2e-18 66.5 17.1 2.8e-18 66.0 17.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW67957.1 - 3.8e-11 42.8 9.2 6.4e-11 42.1 7.2 2.3 2 0 0 2 2 2 1 Ion channel ADIP PF11559.8 RJW67958.1 - 0.046 13.8 4.4 0.91 9.6 0.7 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding MCM_OB PF17207.3 RJW67958.1 - 0.29 11.0 8.8 3.4 7.5 0.0 2.8 2 1 0 2 2 2 0 MCM OB domain FlgH PF02107.16 RJW67958.1 - 6.1 6.4 7.2 0.33 10.6 0.3 2.0 2 0 0 2 2 2 0 Flagellar L-ring protein Pyridoxal_deC PF00282.19 RJW67959.1 - 2.6e-115 385.1 0.0 3.4e-115 384.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 RJW67959.1 - 0.003 16.9 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 RJW67959.1 - 0.0045 15.7 0.0 0.0064 15.2 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 RJW67959.1 - 0.055 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II WD40 PF00400.32 RJW67965.1 - 0.00041 21.1 0.1 4.7 8.3 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat La PF05383.17 RJW67966.1 - 1.9e-22 79.1 0.0 4.2e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 La domain PAM2 PF07145.15 RJW67966.1 - 1.2e-05 24.6 1.5 2.1e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 Ataxin-2 C-terminal region ZapB PF06005.12 RJW67968.1 - 0.0001 22.6 20.7 0.03 14.8 0.4 3.4 3 0 0 3 3 3 2 Cell division protein ZapB DUF5094 PF17015.5 RJW67968.1 - 0.0035 17.5 2.7 0.0035 17.5 2.7 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF5094) HisKA_3 PF07730.13 RJW67968.1 - 0.011 16.2 0.2 0.011 16.2 0.2 3.4 2 1 0 2 2 2 0 Histidine kinase GIT_CC PF16559.5 RJW67968.1 - 0.028 14.3 4.9 0.028 14.3 4.9 3.4 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor MLANA PF14991.6 RJW67968.1 - 0.048 13.9 0.2 0.14 12.4 0.1 1.9 1 1 0 1 1 1 0 Protein melan-A LPP PF04728.13 RJW67968.1 - 0.13 12.7 2.3 0.45 11.0 0.8 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Utp12 PF04003.12 RJW67968.1 - 0.15 12.4 5.1 0.25 11.7 0.1 2.5 2 1 0 2 2 2 0 Dip2/Utp12 Family APG6_N PF17675.1 RJW67968.1 - 0.17 12.4 20.7 0.73 10.4 0.2 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 RJW67968.1 - 0.67 10.6 22.4 1.2 9.9 2.1 3.2 1 1 2 3 3 3 0 Initiation control protein YabA DUF4407 PF14362.6 RJW67968.1 - 0.78 9.0 10.0 2.1 7.6 10.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 RJW67968.1 - 0.94 9.8 12.0 2.3 8.5 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) HALZ PF02183.18 RJW67968.1 - 1.5 9.1 18.5 1.8 8.8 2.0 4.0 3 1 1 4 4 4 0 Homeobox associated leucine zipper Golgin_A5 PF09787.9 RJW67968.1 - 2 7.8 26.9 0.96 8.9 17.9 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 FlxA PF14282.6 RJW67968.1 - 2.3 8.3 14.8 1.5 8.9 1.8 2.6 2 1 0 2 2 2 0 FlxA-like protein WXG100 PF06013.12 RJW67968.1 - 2.9 8.2 10.0 7.7 6.8 2.3 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 RJW67968.1 - 3.1 7.8 5.5 26 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 RJW67968.1 - 3.1 7.3 18.1 69 2.9 18.1 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit NRBF2 PF08961.10 RJW67968.1 - 4.7 6.8 13.6 11 5.6 0.4 2.5 1 1 2 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator SlyX PF04102.12 RJW67968.1 - 8 7.2 23.4 0.19 12.3 1.0 3.8 2 1 1 3 3 3 0 SlyX Fungal_TACC PF12709.7 RJW67968.1 - 10 6.7 19.8 3.1 8.3 3.0 3.4 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins MIR PF02815.19 RJW67970.1 - 9.5e-10 38.6 0.1 1.7e-08 34.6 0.1 2.5 1 1 1 2 2 2 2 MIR domain Glyoxalase PF00903.25 RJW67972.1 - 1.2e-05 25.5 0.0 0.0023 18.1 0.0 3.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 RJW67972.1 - 0.061 13.4 0.0 0.69 10.0 0.0 2.4 3 0 0 3 3 3 0 CppA N-terminal HlyIII PF03006.20 RJW67973.1 - 2.7e-65 220.2 22.4 3.5e-65 219.9 22.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related Pkinase_Tyr PF07714.17 RJW67974.1 - 1e-51 175.8 0.0 1.2e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW67974.1 - 5.7e-18 65.2 0.0 7.3e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RJW67974.1 - 1.2e-05 24.8 0.2 3.9e-05 23.1 0.1 1.8 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RJW67974.1 - 0.058 12.2 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Filament PF00038.21 RJW67975.1 - 0.0015 18.2 4.9 0.0015 18.2 4.9 7.4 6 1 0 7 7 7 2 Intermediate filament protein UPF0242 PF06785.11 RJW67975.1 - 0.0046 17.1 5.6 0.0046 17.1 5.6 7.6 6 1 2 9 9 9 1 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 RJW67975.1 - 0.0054 16.8 8.2 0.0054 16.8 8.2 10.5 8 3 3 11 11 11 3 Designed helical repeat protein 10 domain GRIP PF01465.20 RJW67975.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 GRIP domain Fez1 PF06818.15 RJW67975.1 - 8.5 6.8 94.0 4.4 7.7 13.4 8.2 3 2 4 7 7 7 0 Fez1 RVT_1 PF00078.27 RJW67976.1 - 2.5e-41 141.6 0.0 7.1e-41 140.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW67976.1 - 5.1e-07 29.5 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Ribosomal_L19e PF01280.20 RJW67977.1 - 3.4e-62 208.8 8.9 3.4e-62 208.8 8.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e FAP PF07174.11 RJW67977.1 - 1.2 8.6 34.7 1.7 8.0 34.7 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF1690 PF07956.11 RJW67978.1 - 0.0014 19.0 7.5 0.022 15.2 7.3 2.0 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Pet191_N PF10203.9 RJW67978.1 - 0.011 16.1 1.2 0.016 15.5 1.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 TryThrA_C PF12319.8 RJW67978.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Acetyltransf_1 PF00583.25 RJW67981.1 - 6.9e-05 23.1 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 RJW67981.1 - 0.0003 20.7 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 RJW67981.1 - 0.00082 19.1 0.0 0.0016 18.1 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RJW67981.1 - 0.084 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ubie_methyltran PF01209.18 RJW67982.1 - 4.3e-22 78.6 0.0 5.8e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family BTB_2 PF02214.22 RJW67983.1 - 1.2e-13 51.2 0.0 4.3e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain DpnI_C PF17726.1 RJW67983.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Dam-replacing HTH domain Exo_endo_phos_2 PF14529.6 RJW67985.1 - 8.4e-11 41.8 0.0 1.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-C3H2C3 PF17122.5 RJW67985.1 - 0.002 18.1 0.4 0.0065 16.5 0.4 1.9 1 0 0 1 1 1 1 Zinc-finger Peptidase_C1 PF00112.23 RJW67986.1 - 1.9e-83 279.8 0.2 2.5e-83 279.5 0.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW67986.1 - 3.6e-13 49.7 2.6 8.1e-13 48.6 2.6 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW67986.1 - 0.00074 18.4 1.3 0.2 10.4 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF1986 PF09342.11 RJW67986.1 - 0.08 13.3 0.0 1.3 9.5 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1986) Peptidase_C1 PF00112.23 RJW67987.1 - 8e-130 431.5 0.0 6.2e-67 225.9 0.1 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW67987.1 - 1.6e-16 60.5 12.4 7.4e-08 32.7 2.5 2.5 2 0 0 2 2 2 2 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW67987.1 - 3.2e-09 36.1 5.1 7.3e-05 21.7 0.2 4.2 4 0 0 4 4 4 2 Peptidase C1-like family DUF5486 PF17588.2 RJW67987.1 - 0.039 13.8 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5486) RyR PF02026.16 RJW67987.1 - 0.067 13.4 0.2 21 5.4 0.0 2.4 2 0 0 2 2 2 0 RyR domain CNOT11 PF10155.9 RJW67987.1 - 0.074 13.2 0.2 17 5.6 0.0 2.3 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 Spc42p PF11544.8 RJW67987.1 - 0.079 13.0 0.1 21 5.2 0.0 2.3 2 0 0 2 2 2 0 Spindle pole body component Spc42p Hjc PF01870.18 RJW67987.1 - 0.12 12.3 0.1 28 4.8 0.0 2.4 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) Retrotrans_gag PF03732.17 RJW67987.1 - 0.28 11.5 2.0 24 5.3 0.1 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Occludin_ELL PF07303.13 RJW67987.1 - 0.44 11.3 4.7 15 6.4 0.3 2.4 2 0 0 2 2 2 0 Occludin homology domain Peptidase_C1 PF00112.23 RJW67988.1 - 1.3e-83 280.4 0.5 1.7e-83 280.0 0.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW67988.1 - 1.3e-11 44.8 1.1 2.7e-11 43.7 1.1 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW67988.1 - 0.00013 20.8 1.8 0.035 12.9 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 RJW67989.1 - 5.7e-68 229.3 0.0 7.6e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW67989.1 - 3.3e-11 43.4 2.2 3.5e-11 43.3 1.0 1.6 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW67989.1 - 3.4e-06 26.1 1.2 0.00027 19.9 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 RJW67990.1 - 3.3e-67 226.8 0.0 5e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW67990.1 - 1.1e-11 44.9 3.2 1.8e-11 44.3 3.2 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW67990.1 - 1.6e-07 30.4 0.6 2.5e-05 23.3 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 RJW67992.1 - 4.3e-44 151.2 0.0 6.5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW67992.1 - 1.4e-08 35.0 2.5 2.6e-08 34.2 2.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 RJW67993.1 - 1.6e-64 218.0 3.9 2e-63 214.4 3.9 2.0 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW67993.1 - 2.1e-11 44.1 1.0 4.1e-11 43.1 1.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW67993.1 - 2e-06 26.9 0.1 0.00019 20.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family RVT_1 PF00078.27 RJW67995.1 - 3.9e-09 36.3 0.0 6.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding PF00501.28 RJW67996.1 - 1.5e-88 297.2 0.0 1.8e-88 297.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RJW67996.1 - 0.041 14.9 0.0 0.12 13.4 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ASXH PF13919.6 RJW67997.1 - 4.1e-14 52.8 1.7 1.5e-13 51.0 0.0 2.4 2 0 0 2 2 2 1 Asx homology domain Mss4 PF04421.13 RJW67999.1 - 2.2e-28 98.2 0.0 2.9e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein CpXC PF14353.6 RJW67999.1 - 0.094 12.8 0.6 0.15 12.1 0.0 1.6 1 1 1 2 2 2 0 CpXC protein zf-ISL3 PF14690.6 RJW67999.1 - 0.098 13.3 0.3 0.098 13.3 0.3 1.7 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Myb_DNA-bind_6 PF13921.6 RJW68000.1 - 0.021 15.0 0.5 0.12 12.7 0.1 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain PQ-loop PF04193.14 RJW68001.1 - 1.3e-25 88.9 16.6 2.5e-17 62.4 0.3 3.2 4 0 0 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 RJW68001.1 - 0.00063 20.6 6.7 0.0012 19.6 3.5 2.3 1 1 1 2 2 2 2 ER lumen protein retaining receptor SSXT PF05030.12 RJW68002.1 - 3.2e-19 68.3 0.3 5.4e-19 67.6 0.3 1.3 1 0 0 1 1 1 1 SSXT protein (N-terminal region) SUIM_assoc PF16619.5 RJW68002.1 - 4.7 7.4 5.6 3.2 7.9 0.7 2.8 2 2 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PAS_3 PF08447.12 RJW68003.1 - 1.4e-21 76.6 0.0 4.8e-17 62.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 RJW68003.1 - 3.7e-17 62.5 0.0 6.1e-14 52.1 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 RJW68003.1 - 6.6e-14 51.9 0.0 1.5e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 RJW68003.1 - 3.3e-05 24.1 0.0 0.34 11.2 0.0 2.8 3 0 0 3 3 3 2 PAS domain HLH PF00010.26 RJW68003.1 - 0.00028 20.8 0.9 0.00059 19.7 0.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 RJW68003.1 - 0.00078 19.7 0.0 0.64 10.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold Forkhead PF00250.18 RJW68004.1 - 4.5e-39 132.6 0.2 7.7e-39 131.8 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 RJW68004.1 - 2e-06 28.1 0.0 4.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF3791 PF12668.7 RJW68004.1 - 0.044 13.8 0.1 0.078 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) TNFR_16_TM PF18422.1 RJW68006.1 - 0.11 12.5 0.3 0.11 12.5 0.3 3.3 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain Ig_3 PF13927.6 RJW68007.1 - 6.4e-32 110.0 0.3 6.9e-05 23.4 0.1 8.8 8 1 0 8 8 8 5 Immunoglobulin domain I-set PF07679.16 RJW68007.1 - 4.5e-20 71.5 0.0 0.0016 18.4 0.0 7.4 7 0 0 7 7 7 4 Immunoglobulin I-set domain ig PF00047.25 RJW68007.1 - 2.5e-19 69.2 2.3 0.0075 16.4 0.1 9.3 8 1 0 8 8 8 4 Immunoglobulin domain Ig_2 PF13895.6 RJW68007.1 - 2e-17 63.3 1.0 0.036 14.4 0.0 8.5 8 1 0 8 8 8 3 Immunoglobulin domain V-set PF07686.17 RJW68007.1 - 1.4e-16 60.6 0.1 1.2e-05 25.4 0.0 7.3 8 0 0 8 8 8 4 Immunoglobulin V-set domain fn3 PF00041.21 RJW68007.1 - 1.8e-07 31.4 0.0 0.0017 18.7 0.1 3.3 2 1 0 2 2 2 2 Fibronectin type III domain C2-set_2 PF08205.12 RJW68007.1 - 1.1e-05 25.3 0.1 0.011 15.8 0.0 3.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RJW68007.1 - 0.005 16.4 0.0 1.8 8.2 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin domain V-set_CD47 PF08204.11 RJW68007.1 - 0.06 13.3 0.0 18 5.3 0.0 3.1 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain SAM_decarbox PF01536.16 RJW68009.1 - 0.049 12.6 0.0 0.061 12.3 0.0 1.0 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Peptidase_M14 PF00246.24 RJW68011.1 - 1.6e-59 202.1 0.0 1.9e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 RJW68011.1 - 4.3e-07 30.1 0.0 8.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2817 PF10994.8 RJW68011.1 - 0.0034 16.8 0.8 0.0057 16.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) Stork_head PF10264.9 RJW68012.1 - 8.7e-14 51.5 0.0 3.6e-09 36.7 0.0 2.6 2 0 0 2 2 2 2 Winged helix Storkhead-box1 domain TBPIP PF07106.13 RJW68012.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain Ribosomal_L32e PF01655.18 RJW68014.1 - 3.1e-45 153.0 5.0 3.7e-45 152.8 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ras PF00071.22 RJW68015.1 - 2.1e-05 24.2 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 2 Ras family zf-C2H2_4 PF13894.6 RJW68016.1 - 0.069 14.0 1.3 0.069 14.0 1.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW68016.1 - 0.093 13.2 1.0 0.093 13.2 1.0 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW68017.1 - 0.12 12.7 13.2 2.6 8.4 0.0 4.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FYVE_2 PF02318.16 RJW68017.1 - 1.3 9.2 10.3 5.2 7.3 3.5 3.4 2 1 1 3 3 3 0 FYVE-type zinc finger zf-H2C2_2 PF13465.6 RJW68018.1 - 2.7e-26 90.8 51.1 6.8e-08 32.6 1.2 8.0 8 1 0 8 8 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 RJW68018.1 - 3.3e-23 80.8 49.7 2e-05 24.7 0.5 7.2 8 0 0 8 8 6 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW68018.1 - 1.3e-15 57.2 14.5 0.029 14.6 0.2 6.1 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RJW68018.1 - 6.4e-15 54.6 52.7 0.0027 18.4 3.1 7.5 7 0 0 7 7 5 5 C2H2-type zinc finger zf-met PF12874.7 RJW68018.1 - 1.7e-07 31.4 25.1 0.043 14.2 0.1 6.1 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RJW68018.1 - 2.1e-05 24.7 7.9 0.00063 20.0 1.6 4.2 4 0 0 4 4 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 RJW68018.1 - 2.8e-05 24.5 16.6 0.025 15.0 0.1 5.5 2 1 3 5 5 5 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 RJW68018.1 - 0.00011 22.5 17.2 0.89 9.9 0.2 5.2 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 RJW68018.1 - 0.00011 21.9 9.0 0.022 14.5 0.0 3.8 1 1 3 4 4 4 2 GAGA factor zf-BED PF02892.15 RJW68018.1 - 0.00017 21.5 23.6 2.3 8.3 0.2 5.6 4 1 0 4 4 4 3 BED zinc finger zf-C2H2_6 PF13912.6 RJW68018.1 - 0.0014 18.5 0.5 0.0014 18.5 0.5 6.2 7 0 0 7 7 5 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW68018.1 - 0.0023 17.7 0.1 0.0023 17.7 0.1 6.1 7 0 0 7 7 6 2 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 RJW68018.1 - 0.0024 17.7 4.0 1.7 8.5 0.1 4.4 4 0 0 4 4 4 1 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 RJW68018.1 - 0.011 15.5 0.3 0.011 15.5 0.3 7.3 7 2 0 7 7 6 0 C2H2-type zinc-finger domain Zn_ribbon_SprT PF17283.2 RJW68018.1 - 0.027 14.4 8.5 0.027 14.4 8.5 5.0 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf-C2H2_3rep PF18868.1 RJW68018.1 - 0.093 13.4 6.6 15 6.3 0.2 3.7 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 RJW68018.1 - 0.23 12.0 0.1 0.23 12.0 0.1 5.0 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain BolA PF01722.18 RJW68018.1 - 0.28 11.5 1.6 17 5.7 0.8 3.0 1 1 1 2 2 2 0 BolA-like protein DUF2225 PF09986.9 RJW68018.1 - 9.3 5.9 12.8 3.7 7.2 0.3 4.4 2 1 3 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.17 RJW68020.1 - 4.5e-35 116.9 8.8 1.4e-06 27.9 0.0 8.7 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 RJW68020.1 - 2.6e-32 109.3 9.4 3.3e-07 29.8 1.5 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 RJW68020.1 - 3.4e-26 91.1 7.0 2.8e-25 88.2 4.1 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 RJW68020.1 - 3.7e-21 75.4 1.1 6.4e-06 26.6 0.1 6.4 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 RJW68020.1 - 2.1e-18 65.7 5.0 1.7e-06 27.6 0.8 5.9 5 2 2 7 7 7 2 TPR repeat TPR_8 PF13181.6 RJW68020.1 - 2e-17 61.9 5.8 0.00059 19.8 0.4 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 RJW68020.1 - 1e-14 54.8 3.8 3.8e-05 24.2 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW68020.1 - 1.8e-12 47.0 4.0 0.15 12.9 0.0 7.6 6 3 3 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 RJW68020.1 - 4.7e-12 45.4 10.3 0.013 15.8 0.1 6.2 7 0 0 7 7 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 RJW68020.1 - 1.1e-10 41.4 5.9 0.00043 20.4 0.2 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 RJW68020.1 - 3.8e-09 36.6 0.7 0.0052 17.3 0.0 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW68020.1 - 3.8e-09 36.7 12.9 0.0085 16.4 0.9 5.4 3 2 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW68020.1 - 1.9e-06 28.0 20.6 0.01 16.0 2.7 4.6 2 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RJW68020.1 - 3.1e-06 26.8 11.1 4.2 7.6 0.1 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat NYD-SP12_N PF15015.6 RJW68020.1 - 1.3e-05 23.8 0.9 0.0015 17.0 0.1 2.3 2 0 0 2 2 2 2 Spermatogenesis-associated, N-terminal PknG_TPR PF16918.5 RJW68020.1 - 0.00034 19.4 0.1 0.002 16.9 0.0 2.1 2 1 0 2 2 2 1 Protein kinase G tetratricopeptide repeat SRP_TPR_like PF17004.5 RJW68020.1 - 0.00099 19.1 4.4 0.11 12.5 0.8 3.5 2 1 1 3 3 3 1 Putative TPR-like repeat Fis1_TPR_C PF14853.6 RJW68020.1 - 0.002 18.2 13.0 0.64 10.1 0.2 6.3 8 0 0 8 8 6 1 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 RJW68020.1 - 0.0024 17.9 4.5 1.3 9.1 0.1 4.4 3 1 0 3 3 3 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 RJW68020.1 - 0.0078 16.7 5.1 7.4 7.0 0.1 4.1 2 1 1 4 4 4 0 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 RJW68020.1 - 0.076 12.6 0.0 13 5.5 0.0 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 RJW68020.1 - 0.09 13.1 0.8 2.6 8.4 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 RJW68020.1 - 0.18 11.2 4.1 0.74 9.2 0.0 3.1 3 1 1 4 4 4 0 Coatomer epsilon subunit BORCS7 PF16088.5 RJW68020.1 - 0.19 12.0 0.9 0.46 10.8 0.2 2.0 2 0 0 2 2 1 0 BLOC-1-related complex sub-unit 7 TPR_10 PF13374.6 RJW68020.1 - 0.56 10.2 7.1 48 4.0 0.4 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 RJW68020.1 - 0.77 9.9 17.8 7.2 6.8 0.1 6.1 5 1 2 7 7 7 0 MIT (microtubule interacting and transport) domain YL1_C PF08265.11 RJW68024.1 - 1.9e-08 33.9 0.1 3.5e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Transglut_core PF01841.19 RJW68026.1 - 2.9e-06 27.7 0.0 6.2e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Transglutaminase-like superfamily Big_3 PF07523.12 RJW68026.1 - 0.062 13.6 0.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) RVT_1 PF00078.27 RJW68028.1 - 5.2e-06 26.1 0.0 7.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PrgI PF12666.7 RJW68029.1 - 0.1 13.3 0.4 0.1 13.3 0.4 1.9 3 0 0 3 3 3 0 PrgI family protein Pkinase PF00069.25 RJW68030.1 - 1.5e-57 195.0 0.2 8e-57 192.6 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68030.1 - 1.8e-39 135.6 0.0 3e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW68030.1 - 0.0016 17.3 0.0 0.004 16.0 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW68030.1 - 0.0021 17.4 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Nop14 PF04147.12 RJW68030.1 - 0.75 7.9 7.4 1.5 6.9 7.4 1.4 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 RJW68030.1 - 0.9 8.6 15.3 7.4 5.6 0.2 2.6 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Peptidase_M8 PF01457.16 RJW68031.1 - 2.2e-52 178.5 0.0 2.1e-51 175.2 0.0 2.0 1 1 0 1 1 1 1 Leishmanolysin Meis_PKNOX_N PF16493.5 RJW68033.1 - 1.1e-40 137.8 0.2 1.8e-40 137.1 0.2 1.3 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 RJW68033.1 - 1.9e-20 72.5 4.5 5.9e-20 70.9 0.5 2.5 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 RJW68033.1 - 2.9e-08 33.4 0.2 6.5e-08 32.3 0.2 1.6 1 0 0 1 1 1 1 Homeodomain PBP PF01161.20 RJW68034.1 - 7.9e-09 35.9 0.0 1.5e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GDNF PF02351.16 RJW68036.1 - 1.2e-05 26.2 86.0 0.069 14.1 11.1 6.5 6 0 0 6 6 6 5 GDNF/GAS1 domain WD40 PF00400.32 RJW68037.1 - 3.5e-19 68.8 26.8 6.7e-07 29.9 0.1 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Hira PF07569.11 RJW68037.1 - 6e-18 65.4 0.0 1.5e-16 60.9 0.0 2.6 2 0 0 2 2 2 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 RJW68037.1 - 1.9e-07 31.3 2.5 3.6 7.9 0.0 6.1 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 RJW68037.1 - 0.0068 16.2 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 HIRA B motif Prok-RING_2 PF14445.6 RJW68037.1 - 0.47 10.6 2.9 5.3 7.3 1.3 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 Ribosomal_L12 PF00542.19 RJW68038.1 - 3.2e-21 75.4 5.1 6.9e-21 74.4 5.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 RJW68038.1 - 2.8e-08 33.3 2.5 4e-08 32.8 0.3 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Itfg2 PF15907.5 RJW68041.1 - 2e-50 171.8 0.0 4.5e-50 170.6 0.0 1.5 1 1 0 1 1 1 1 Integrin-alpha FG-GAP repeat-containing protein 2 AMP-binding PF00501.28 RJW68041.1 - 2.5e-36 125.2 0.0 5.5e-36 124.1 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Integrase_H2C2 PF17921.1 RJW68041.1 - 5.2e-12 45.7 0.1 1.1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RJW68041.1 - 2.3e-11 43.9 0.0 7.3e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Integrase core domain ACAS_N PF16177.5 RJW68041.1 - 1e-07 31.7 0.7 2.2e-07 30.7 0.7 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus zf-H2C2 PF09337.10 RJW68041.1 - 6.3e-05 23.1 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 RJW68041.1 - 0.0045 16.7 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain AMP-binding_C PF13193.6 RJW68041.1 - 0.0062 17.5 0.0 0.013 16.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2474 PF10617.9 RJW68041.1 - 0.14 12.1 4.9 0.3 11.0 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Pkinase PF00069.25 RJW68042.1 - 1.5e-57 195.0 0.4 1.4e-56 191.8 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68042.1 - 1e-27 97.0 0.0 3.8e-27 95.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW68042.1 - 4.6e-06 26.2 2.3 9e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF1664 PF07889.12 RJW68042.1 - 2.4e-05 24.4 37.9 0.038 14.0 5.9 5.6 3 2 1 5 5 5 4 Protein of unknown function (DUF1664) Spc7 PF08317.11 RJW68042.1 - 0.0015 17.5 10.7 0.0015 17.5 10.7 4.9 2 1 3 5 5 5 4 Spc7 kinetochore protein APH PF01636.23 RJW68042.1 - 0.017 15.1 0.0 0.017 15.1 0.0 3.3 4 1 0 4 4 4 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RJW68042.1 - 0.041 12.9 0.2 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Seadornavirus VP7 TetR_C_24 PF17932.1 RJW68042.1 - 0.06 13.6 3.8 5.5 7.3 0.6 3.6 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Peripla_BP_2 PF01497.18 RJW68042.1 - 1.5 8.3 5.0 0.65 9.5 0.7 2.4 2 0 0 2 2 2 0 Periplasmic binding protein Proteasome PF00227.26 RJW68043.1 - 4.9e-55 186.0 0.0 7.2e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RJW68043.1 - 1.2e-13 50.4 0.0 2.3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature UbiA PF01040.18 RJW68044.1 - 7.8e-05 22.1 0.2 0.00011 21.6 0.1 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family SNF2_N PF00176.23 RJW68047.1 - 5.7e-65 219.3 0.0 9.4e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW68047.1 - 6.9e-15 55.4 0.0 1.4e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW68047.1 - 2.1e-07 31.1 0.0 5.9e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DBINO PF13892.6 RJW68047.1 - 0.00011 22.6 1.6 0.00038 20.8 1.6 2.0 1 0 0 1 1 1 1 DNA-binding domain HDA2-3 PF11496.8 RJW68047.1 - 0.00014 21.2 0.0 0.001 18.3 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 eIF3_N PF09440.10 RJW68048.1 - 0.22 12.0 0.0 0.27 11.7 0.0 1.1 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Rootletin PF15035.6 RJW68049.1 - 1.5e-49 168.6 30.0 1.5e-49 168.6 30.0 14.7 3 3 10 13 13 13 2 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 RJW68049.1 - 0.00018 21.7 16.0 0.00018 21.7 16.0 21.0 3 3 20 25 25 25 1 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.6 RJW68049.1 - 0.00038 20.5 14.9 0.00038 20.5 14.9 20.6 15 6 6 21 21 21 3 Centrosome localisation domain of PPC89 EzrA PF06160.12 RJW68049.1 - 0.0005 18.4 31.4 0.0005 18.4 31.4 10.7 3 3 4 11 11 11 4 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 RJW68049.1 - 0.0017 18.4 21.7 0.0017 18.4 21.7 17.7 5 4 10 16 16 16 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HSBP1 PF06825.12 RJW68049.1 - 0.063 13.2 11.9 0.057 13.3 0.5 5.1 5 0 0 5 5 5 0 Heat shock factor binding protein 1 PAN_1 PF00024.26 RJW68051.1 - 0.013 15.4 0.9 0.036 14.0 0.9 1.7 1 0 0 1 1 1 0 PAN domain PAN_1 PF00024.26 RJW68052.1 - 0.0003 20.7 0.6 0.00067 19.6 0.6 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RJW68052.1 - 1.7 8.6 4.4 2.1 8.3 1.0 2.2 2 0 0 2 2 2 0 PAN domain Tetraspanin PF00335.20 RJW68053.1 - 1.1e-10 41.6 1.9 1.9e-09 37.6 0.2 2.3 2 0 0 2 2 2 2 Tetraspanin family DUF2721 PF11026.8 RJW68053.1 - 0.077 12.9 0.3 0.077 12.9 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Cadherin PF00028.17 RJW68054.1 - 0.0011 19.3 0.0 0.085 13.3 0.0 2.6 2 0 0 2 2 2 2 Cadherin domain LicD PF04991.13 RJW68055.1 - 0.00065 19.9 0.1 0.0012 19.1 0.1 1.4 1 0 0 1 1 1 1 LicD family WD40 PF00400.32 RJW68056.1 - 2.3e-13 50.4 7.4 0.00028 21.6 0.1 5.4 5 1 1 6 6 6 3 WD domain, G-beta repeat DUF2875 PF11394.8 RJW68056.1 - 0.029 13.2 0.1 0.044 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) RVT_1 PF00078.27 RJW68057.1 - 3.8e-27 95.2 0.1 5.1e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf_Rg PF17915.1 RJW68057.1 - 0.057 12.8 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Reverse gyrase zinc finger SF3A2 PF16835.5 RJW68060.1 - 4.8e-39 132.6 0.3 9.6e-39 131.7 0.3 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 RJW68060.1 - 2.1e-07 31.1 2.0 4.5e-07 30.0 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 RJW68060.1 - 3.1e-05 23.9 0.7 5.9e-05 23.0 0.5 1.5 1 1 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 RJW68060.1 - 0.35 10.4 3.4 0.72 9.5 3.4 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like zf-C2H2_jaz PF12171.8 RJW68060.1 - 6.1 7.2 6.1 10 6.5 4.5 2.2 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ras PF00071.22 RJW68063.1 - 2.9e-56 189.5 0.3 4.4e-56 189.0 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW68063.1 - 7.2e-35 119.8 0.1 1.2e-34 119.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW68063.1 - 1.7e-13 50.4 0.2 2.6e-13 49.8 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW68063.1 - 0.00043 20.3 0.0 0.00092 19.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RJW68063.1 - 0.00047 19.7 0.0 0.00079 18.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RJW68063.1 - 0.0014 18.3 0.1 0.0048 16.5 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RJW68063.1 - 0.0081 16.1 0.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 RJW68063.1 - 0.0082 15.5 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 RJW68063.1 - 0.16 11.5 0.0 3.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B LicD PF04991.13 RJW68065.1 - 0.0065 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 LicD family CPSase_L_D2 PF02786.17 RJW68066.1 - 4.4e-80 268.1 0.0 6.6e-80 267.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RJW68066.1 - 1.4e-43 147.9 0.1 2.7e-43 147.0 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RJW68066.1 - 7.2e-33 112.9 0.0 1.9e-32 111.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 RJW68066.1 - 2.4e-17 62.5 0.5 6.2e-17 61.2 0.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 RJW68066.1 - 5.7e-10 39.6 0.2 1.8e-08 34.7 0.1 2.8 2 1 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 RJW68066.1 - 1.6e-08 34.3 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 RJW68066.1 - 8.6e-08 31.9 0.1 2.6e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 RJW68066.1 - 7e-07 29.0 0.9 0.002 17.9 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.11 RJW68066.1 - 2.8e-05 23.8 0.0 9.6e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 RJW68066.1 - 0.00098 19.2 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 RJW68066.1 - 0.013 16.2 0.1 10 6.9 0.1 2.7 2 0 0 2 2 2 0 HlyD family secretion protein GARS_A PF01071.19 RJW68066.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_D23 PF16576.5 RJW68066.1 - 0.12 11.6 0.2 3.5 6.8 0.0 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion MULE PF10551.9 RJW68068.1 - 8.6e-17 61.3 0.3 9.6e-16 58.0 0.3 2.4 2 0 0 2 2 2 1 MULE transposase domain PHD PF00628.29 RJW68068.1 - 4.4e-06 26.5 14.7 1.3e-05 25.0 14.7 1.9 1 0 0 1 1 1 1 PHD-finger Transposase_mut PF00872.18 RJW68068.1 - 0.015 14.2 0.2 0.032 13.1 0.2 1.5 1 0 0 1 1 1 0 Transposase, Mutator family DUF4817 PF16087.5 RJW68070.1 - 1e-13 50.9 0.0 1.8e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_IclR PF09339.10 RJW68070.1 - 0.1 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Phage_antitermQ PF06530.12 RJW68070.1 - 0.11 12.4 0.1 1.5 8.7 0.0 2.1 1 1 1 2 2 2 0 Phage antitermination protein Q NqrM PF04400.13 RJW68075.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 (Na+)-NQR maturation NqrM KA1 PF02149.19 RJW68080.1 - 1.8e-07 30.8 0.0 3.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 UBA PF00627.31 RJW68080.1 - 0.028 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain ETC_C1_NDUFA4 PF04800.12 RJW68083.1 - 2.4e-36 123.8 0.0 3.5e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region MFS_1 PF07690.16 RJW68084.1 - 2.5e-20 72.7 43.2 5e-16 58.6 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PI-PLC-X PF00388.19 RJW68086.1 - 1.6e-08 34.3 0.0 9.3e-08 31.8 0.0 2.2 2 1 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.11 RJW68086.1 - 5.2e-06 26.9 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like Tyrosinase PF00264.20 RJW68086.1 - 0.33 11.2 0.0 0.33 11.2 0.0 2.7 3 1 1 4 4 4 0 Common central domain of tyrosinase RVT_1 PF00078.27 RJW68087.1 - 1.4e-44 152.2 0.0 2.3e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH PF00169.29 RJW68087.1 - 3.7e-12 46.7 0.2 1.2e-11 45.1 0.2 1.9 1 0 0 1 1 1 1 PH domain PDZ_6 PF17820.1 RJW68087.1 - 8.9e-07 28.7 0.0 2.3e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Exo_endo_phos_2 PF14529.6 RJW68087.1 - 9.8e-07 28.6 0.0 2.5e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW68087.1 - 1.1e-06 28.3 1.0 2.9e-06 27.0 0.4 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family SAM_1 PF00536.30 RJW68087.1 - 3.9e-06 27.2 0.0 8.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 RJW68087.1 - 7.1e-06 26.3 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 RJW68087.1 - 2.5e-05 24.3 0.0 5.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CRIC_ras_sig PF10534.9 RJW68087.1 - 4.4e-05 23.6 0.0 0.00018 21.6 0.0 2.0 1 1 1 2 2 2 1 Connector enhancer of kinase suppressor of ras PDZ_2 PF13180.6 RJW68087.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PH_11 PF15413.6 RJW68087.1 - 0.75 10.2 4.4 6 7.4 4.4 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain VHS PF00790.19 RJW68088.1 - 8.1e-28 97.0 0.0 1.8e-27 95.9 0.0 1.6 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 RJW68088.1 - 1.2e-09 38.3 0.1 3.9e-09 36.7 0.1 1.9 1 0 0 1 1 1 1 GAT domain PBP1_TM PF14812.6 RJW68089.1 - 0.0095 16.3 4.1 0.014 15.7 4.1 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 RJW68089.1 - 0.013 15.3 6.6 0.015 15.0 6.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein UPF0560 PF10577.9 RJW68089.1 - 0.07 11.6 1.6 0.086 11.3 1.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RXT2_N PF08595.11 RJW68089.1 - 0.18 11.8 1.2 0.21 11.6 1.2 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 RJW68089.1 - 0.23 10.7 6.8 0.28 10.5 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RJW68089.1 - 0.45 8.6 6.5 0.54 8.3 6.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 RJW68089.1 - 1.9 8.9 12.5 3.1 8.3 12.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 RJW68089.1 - 3.3 7.3 4.7 3.9 7.0 4.7 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 RJW68089.1 - 3.4 6.7 12.1 4.3 6.4 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HSP70 PF00012.20 RJW68091.1 - 1.1e-65 222.0 6.6 8.2e-64 215.8 0.0 2.4 3 0 0 3 3 3 2 Hsp70 protein DUF4834 PF16118.5 RJW68091.1 - 1 10.4 5.2 1.2 10.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) RVT_1 PF00078.27 RJW68092.1 - 9.6e-29 100.5 0.0 1.7e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIH1_CS PF18201.1 RJW68093.1 - 3.8e-10 40.1 0.1 9.2e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 PIH1 CS-like domain Pih1_fungal_CS PF18482.1 RJW68093.1 - 0.021 15.4 0.4 0.046 14.2 0.4 1.6 1 0 0 1 1 1 0 Fungal Pih1 CS domain COPIIcoated_ERV PF07970.12 RJW68094.1 - 8.5e-43 146.7 1.9 1.2e-42 146.3 1.9 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RJW68094.1 - 4.2e-25 87.9 0.3 7.2e-25 87.2 0.3 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_A2B PF12384.8 RJW68094.1 - 0.05 13.1 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase Dynein_light PF01221.18 RJW68095.1 - 4e-32 110.4 0.9 5.1e-32 110.1 0.9 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 zf-C2HC_2 PF13913.6 RJW68096.1 - 3.3e-09 36.4 10.1 0.00042 20.1 1.0 2.8 2 0 0 2 2 2 2 zinc-finger of a C2HC-type DZR PF12773.7 RJW68096.1 - 0.0012 18.8 0.8 0.0012 18.8 0.8 3.2 3 0 0 3 3 3 1 Double zinc ribbon zf-ribbon_3 PF13248.6 RJW68096.1 - 0.013 14.9 2.0 0.013 14.9 2.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 RJW68096.1 - 0.21 11.4 8.6 2.8 7.8 8.6 2.7 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RJW68096.1 - 0.42 11.4 7.1 0.13 13.1 1.0 2.7 3 0 0 3 3 3 0 zinc-ribbon family Zf_RING PF16744.5 RJW68096.1 - 1.4 9.1 4.6 11 6.2 0.2 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger PLATZ PF04640.14 RJW68096.1 - 3.4 8.3 6.8 11 6.7 0.5 3.5 4 0 0 4 4 4 0 PLATZ transcription factor NOB1_Zn_bind PF08772.11 RJW68096.1 - 3.6 7.8 10.1 0.095 12.9 1.9 2.6 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like HypA PF01155.19 RJW68096.1 - 4.5 7.3 11.2 0.81 9.7 0.7 3.1 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2 PF00096.26 RJW68096.1 - 7.6 7.2 10.7 17 6.1 0.2 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF3323 PF11796.8 RJW68098.1 - 0.021 14.7 0.0 0.024 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) ASC PF00858.24 RJW68101.1 - 1.4e-10 40.7 5.3 1.4e-10 40.7 5.3 2.5 3 0 0 3 3 3 2 Amiloride-sensitive sodium channel Guanylate_kin PF00625.21 RJW68102.1 - 9.5e-40 136.2 0.0 1.5e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 RJW68102.1 - 1.5e-05 24.5 0.0 3.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RJW68102.1 - 2.6e-05 23.7 0.1 6.7e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RJW68102.1 - 0.0077 16.1 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF2826 PF11442.8 RJW68102.1 - 0.014 15.3 0.3 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2826) DUF929 PF06053.11 RJW68103.1 - 0.12 11.6 4.4 0.19 11.0 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) ODV-E18 PF10717.9 RJW68103.1 - 0.14 12.0 3.3 0.26 11.2 3.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3139 PF11337.8 RJW68103.1 - 0.35 11.5 6.7 0.78 10.4 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) TMEM154 PF15102.6 RJW68103.1 - 7.8 6.4 6.9 14 5.6 6.9 1.4 1 0 0 1 1 1 0 TMEM154 protein family DDE_Tnp_IS1595 PF12762.7 RJW68104.1 - 4.6e-10 39.7 0.0 8.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS1 PF03400.13 RJW68104.1 - 0.0037 17.6 0.0 0.0061 16.9 0.0 1.3 1 0 0 1 1 1 1 IS1 transposase BMP2K_C PF15282.6 RJW68105.1 - 0.033 14.0 0.6 0.033 14.0 0.6 1.2 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus Peptidase_M14 PF00246.24 RJW68106.1 - 8.5e-75 252.2 0.0 1.1e-74 251.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 RJW68106.1 - 7.1e-14 52.0 0.0 1.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Homeobox_KN PF05920.11 RJW68108.1 - 3.7e-11 42.7 0.0 7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RJW68108.1 - 4.2e-06 26.5 0.0 9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 RJW68110.1 - 3.8e-46 157.6 0.0 6.8e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68110.1 - 8.2e-16 58.1 0.0 2.8e-15 56.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase HipN PF18253.1 RJW68110.1 - 0.039 13.6 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain UAA PF08449.11 RJW68111.1 - 6.2e-20 71.6 11.3 7.2e-20 71.4 11.3 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RJW68111.1 - 3.5e-07 30.5 13.2 4.5e-07 30.1 13.2 1.1 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.16 RJW68111.1 - 0.0023 17.3 5.3 0.003 16.9 5.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 RJW68111.1 - 0.0042 16.3 0.4 0.0065 15.7 0.3 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter TMEM234 PF10639.9 RJW68111.1 - 0.0066 16.5 5.0 0.0076 16.3 4.6 1.4 1 1 0 1 1 1 1 Putative transmembrane family 234 EmrE PF13536.6 RJW68111.1 - 0.12 12.0 7.0 0.14 11.7 7.0 1.0 1 0 0 1 1 1 0 Putative multidrug resistance efflux transporter DUF5090 PF17009.5 RJW68111.1 - 0.15 12.0 5.6 0.15 12.0 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) VP7 PF00434.18 RJW68112.1 - 0.022 13.9 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Glycoprotein VP7 Pox_A_type_inc PF04508.12 RJW68113.1 - 0.019 14.8 10.8 0.18 11.7 0.2 6.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat PNKP_ligase PF16542.5 RJW68113.1 - 0.12 11.9 19.3 0.014 14.9 10.3 2.3 1 1 1 2 2 2 0 PNKP adenylyltransferase domain, ligase domain APG6_N PF17675.1 RJW68113.1 - 0.27 11.8 69.0 4.8 7.7 3.5 5.5 2 1 3 5 5 5 0 Apg6 coiled-coil region DUF4407 PF14362.6 RJW68113.1 - 0.41 10.0 45.6 24 4.2 13.7 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) PKcGMP_CC PF16808.5 RJW68113.1 - 6.6 6.7 14.2 0.12 12.3 0.7 4.3 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sep15_SelM PF08806.11 RJW68114.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Sep15/SelM redox domain zf-RING_2 PF13639.6 RJW68115.1 - 1.3e-06 28.6 9.5 1.3e-06 28.6 9.5 3.1 2 0 0 2 2 2 1 Ring finger domain Filamin PF00630.19 RJW68115.1 - 1.8e-06 28.7 0.0 3.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-RING_5 PF14634.6 RJW68115.1 - 1.1e-05 25.3 9.6 1.1e-05 25.3 9.6 2.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RJW68115.1 - 1.7e-05 24.5 7.5 1.7e-05 24.5 7.5 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW68115.1 - 2.6e-05 24.1 3.8 2.6e-05 24.1 3.8 3.0 2 1 1 3 3 2 1 RING-type zinc-finger zf-B_box PF00643.24 RJW68115.1 - 4.2e-05 23.6 4.2 4.2e-05 23.6 4.2 3.3 3 0 0 3 3 3 1 B-box zinc finger Prok-RING_4 PF14447.6 RJW68115.1 - 0.00015 21.6 7.9 0.00015 21.6 7.9 2.9 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RJW68115.1 - 0.00063 19.6 9.5 0.00063 19.6 9.5 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RJW68115.1 - 0.0017 18.1 8.1 0.0017 18.1 8.1 2.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain NHL PF01436.21 RJW68115.1 - 0.0018 18.2 0.0 16 5.7 0.0 4.6 4 0 0 4 4 4 0 NHL repeat zf-C3HC4_4 PF15227.6 RJW68115.1 - 0.0022 18.1 2.9 0.0022 18.1 2.9 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 RJW68115.1 - 0.048 13.4 4.0 0.14 11.9 4.0 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger TORC_N PF12884.7 RJW68115.1 - 0.058 14.2 0.0 0.17 12.7 0.0 1.8 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus zf-C3HC4_2 PF13923.6 RJW68115.1 - 1.2 9.0 21.6 0.02 14.7 9.3 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Kelch_1 PF01344.25 RJW68117.1 - 5e-70 230.9 9.1 1.4e-14 53.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RJW68117.1 - 2e-33 113.6 4.2 1.8e-09 37.6 0.0 6.5 2 1 4 6 6 6 5 Kelch motif BTB PF00651.31 RJW68117.1 - 1.1e-29 102.9 0.1 1.9e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 RJW68117.1 - 2.2e-28 98.0 2.4 0.0001 22.2 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 RJW68117.1 - 8.3e-25 85.8 1.5 0.00011 22.0 0.0 6.2 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 RJW68117.1 - 8.7e-25 86.8 0.1 2.1e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 RJW68117.1 - 8.6e-19 67.4 6.2 0.00011 22.3 0.1 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW68117.1 - 5.5e-07 29.4 5.6 0.12 12.4 0.0 4.9 5 0 0 5 5 5 2 Kelch motif PQQ_3 PF13570.6 RJW68117.1 - 0.014 15.8 4.2 0.16 12.5 0.1 4.2 5 0 0 5 5 5 0 PQQ-like domain DUF3509 PF12021.8 RJW68118.1 - 0.0039 16.9 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) P2X_receptor PF00864.19 RJW68119.1 - 8.6e-84 281.7 0.0 6.9e-54 183.3 0.1 2.2 2 0 0 2 2 2 2 ATP P2X receptor p450 PF00067.22 RJW68120.1 - 8.8e-38 130.2 0.6 4.9e-25 88.2 0.1 3.1 1 1 2 3 3 3 3 Cytochrome P450 GCM PF03615.15 RJW68121.1 - 7.2e-61 204.2 4.4 1.4e-60 203.3 4.4 1.4 1 0 0 1 1 1 1 GCM motif protein Ferritin PF00210.24 RJW68124.1 - 1.1e-33 116.2 0.0 1.3e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 RJW68124.1 - 2.7e-06 27.8 0.2 4.1e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.10 RJW68124.1 - 0.025 14.9 0.2 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) COQ7 PF03232.13 RJW68124.1 - 0.083 12.7 0.2 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 zf_CCCH_4 PF18345.1 RJW68127.1 - 1.5e-07 31.2 3.4 2.7e-07 30.4 3.4 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 RJW68127.1 - 2.8e-06 27.1 2.2 5.3e-06 26.2 2.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RJW68127.1 - 3.8e-06 26.6 1.0 8.4e-06 25.5 1.0 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Med26 PF08711.11 RJW68127.1 - 5.1e-05 23.2 0.4 0.00014 21.8 0.1 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Torus PF16131.5 RJW68127.1 - 0.0079 16.9 0.4 0.016 15.9 0.4 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 RJW68127.1 - 0.3 11.6 2.0 0.59 10.7 2.0 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger NCBP3 PF10309.9 RJW68128.1 - 2.9e-05 23.8 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 P2X_receptor PF00864.19 RJW68129.1 - 5.5e-90 302.1 0.1 4e-87 292.7 0.1 2.1 1 1 0 1 1 1 1 ATP P2X receptor PRMT5_TIM PF17285.2 RJW68129.1 - 0.13 11.4 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 PRMT5 TIM barrel domain Glyco_hydro_63 PF03200.16 RJW68130.1 - 1.8e-171 571.3 0.0 3.5e-171 570.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 RJW68130.1 - 4.2e-39 135.0 0.0 9.7e-39 133.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Cadherin PF00028.17 RJW68132.1 - 1.6e-56 188.8 2.8 3.4e-16 59.4 0.0 9.6 7 4 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 RJW68132.1 - 0.0055 16.5 0.0 4.8 7.1 0.0 3.7 3 0 0 3 3 3 2 Cadherin-like zf-C2H2 PF00096.26 RJW68133.1 - 1.1e-22 79.1 49.8 1.1e-05 25.6 2.7 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW68133.1 - 6.5e-19 67.4 51.5 7e-07 29.4 0.9 7.0 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW68133.1 - 2.4e-16 59.0 47.4 0.0019 18.8 2.4 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW68133.1 - 1.4e-05 25.2 32.7 0.19 12.0 0.6 6.7 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 RJW68133.1 - 0.0062 16.8 23.4 0.49 10.7 5.7 3.7 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 RJW68133.1 - 0.023 14.7 45.9 0.33 11.0 1.1 6.1 6 0 0 6 6 6 0 C2H2-type zinc finger zf-Di19 PF05605.12 RJW68133.1 - 0.028 14.7 30.8 0.34 11.2 0.6 4.9 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 RJW68133.1 - 0.15 12.1 31.1 0.5 10.4 1.3 6.0 4 1 2 6 6 6 0 BED zinc finger zinc_ribbon_15 PF17032.5 RJW68133.1 - 0.21 12.3 15.5 1.8 9.4 1.3 3.5 1 1 2 3 3 3 0 zinc-ribbon family zf-LYAR PF08790.11 RJW68133.1 - 0.33 10.9 27.0 1.8 8.5 0.1 5.5 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 RJW68133.1 - 0.43 10.7 22.5 5.2 7.3 4.7 5.4 4 2 1 5 5 5 0 Zinc ribbon domain Yippee-Mis18 PF03226.14 RJW68133.1 - 1.9 8.7 12.6 2.9 8.1 0.2 3.0 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly XPA_N PF01286.18 RJW68133.1 - 2.1 8.5 20.9 5.5 7.1 0.3 5.8 6 0 0 6 6 6 0 XPA protein N-terminal zf-AN1 PF01428.16 RJW68133.1 - 2.8 8.2 26.9 8.2 6.7 0.2 6.1 6 0 0 6 6 6 0 AN1-like Zinc finger zf-C2HE PF16278.5 RJW68133.1 - 3.4 8.2 36.9 10 6.6 2.9 6.9 2 1 4 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 RJW68133.1 - 3.8 7.2 22.5 3.8 7.2 3.3 4.5 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain HypA PF01155.19 RJW68133.1 - 4.1 7.4 15.4 38 4.4 5.9 3.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_3rep PF18868.1 RJW68133.1 - 5.7 7.6 22.2 43 4.8 2.6 5.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 RJW68133.1 - 5.9 6.6 21.0 3.5 7.3 0.0 5.1 6 0 0 6 6 5 0 Ubiquitin-Binding Zinc Finger DUF3268 PF11672.8 RJW68133.1 - 6.4 7.1 10.6 0.093 13.1 1.1 2.6 2 1 1 3 3 3 0 zinc-finger-containing domain Apo-CII PF05355.11 RJW68134.1 - 8.9e-09 35.4 9.2 4.4 7.5 0.1 5.1 5 0 0 5 5 5 5 Apolipoprotein C-II DUF3941 PF13081.6 RJW68134.1 - 0.0004 20.6 0.5 1.8e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF3941) CybS PF05328.12 RJW68134.1 - 0.001 18.7 0.1 20 4.9 0.0 3.7 1 1 3 4 4 4 3 CybS, succinate dehydrogenase cytochrome B small subunit 3HCDH PF00725.22 RJW68134.1 - 0.026 15.1 1.1 2e+02 2.6 0.0 4.1 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4407 PF14362.6 RJW68135.1 - 0.16 11.3 30.8 0.3 10.4 14.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF2634 PF10934.8 RJW68135.1 - 0.46 10.6 3.4 1.1 9.4 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Fringe PF02434.16 RJW68136.1 - 1.2e-08 34.7 0.1 7.5e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RJW68136.1 - 5.9e-06 26.2 0.1 0.076 12.8 0.0 2.3 1 1 1 2 2 2 2 Galactosyltransferase DUF604 PF04646.12 RJW68136.1 - 0.025 14.0 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Asp_protease_2 PF13650.6 RJW68137.1 - 0.03 15.0 0.0 0.077 13.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Fringe PF02434.16 RJW68138.1 - 3.5e-09 36.5 0.1 1.6e-08 34.3 0.1 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RJW68138.1 - 3.4e-06 27.0 0.1 0.06 13.1 0.0 2.3 1 1 1 2 2 2 2 Galactosyltransferase OTU PF02338.19 RJW68139.1 - 0.024 15.1 0.7 0.065 13.7 0.7 1.8 1 1 0 1 1 1 0 OTU-like cysteine protease Cation_ATPase_C PF00689.21 RJW68140.1 - 3.8e-42 144.1 4.7 3.8e-42 144.1 4.7 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 RJW68140.1 - 1.8e-18 66.4 0.0 3.5e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RJW68140.1 - 2.4e-14 54.2 0.6 2.5e-12 47.5 0.6 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.8 RJW68140.1 - 2.4e-13 50.3 1.2 7.5e-13 48.7 1.2 1.9 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal E1-E2_ATPase PF00122.20 RJW68140.1 - 5.3e-09 35.9 0.2 5.3e-09 35.9 0.2 3.2 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase_3 PF08282.12 RJW68140.1 - 3.5e-07 30.2 0.3 5.2e-05 23.1 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase A_deaminase PF00962.22 RJW68141.1 - 4e-18 65.8 0.1 7.5e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase TRM13 PF05206.14 RJW68142.1 - 6.8e-68 229.0 0.0 8.8e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 RJW68142.1 - 9.3e-07 28.6 0.1 3.1e-06 26.9 0.1 2.0 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 RJW68142.1 - 0.5 10.3 5.8 1.1 9.2 3.1 2.8 2 1 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 RJW68145.1 - 1.2e-62 211.7 0.0 2.7e-62 210.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68145.1 - 1.2e-43 149.2 0.0 2.6e-43 148.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase MIT PF04212.18 RJW68145.1 - 1.8e-10 40.7 5.7 5.1e-10 39.3 5.7 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain APH PF01636.23 RJW68145.1 - 0.0014 18.6 0.0 0.0035 17.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RJW68145.1 - 0.0033 16.8 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RJW68145.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RJW68145.1 - 0.035 12.9 0.0 0.1 11.3 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 RJW68145.1 - 0.05 12.6 0.0 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 RJW68145.1 - 0.2 11.2 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RVT_1 PF00078.27 RJW68146.1 - 2.6e-10 40.2 0.0 3.9e-09 36.3 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) A_deaminase PF00962.22 RJW68148.1 - 5.8e-64 216.5 0.0 7e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase MTS PF05175.14 RJW68150.1 - 0.0003 20.4 0.0 0.0017 17.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 RJW68150.1 - 0.1 13.3 0.0 1.8 9.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.24 RJW68153.1 - 6.9e-19 68.0 13.0 9.9e-13 47.7 1.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RJW68153.1 - 8.2e-15 54.6 19.1 8.2e-15 54.6 19.1 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Pox_A9 PF04835.12 RJW68153.1 - 0.33 11.1 3.1 1.2 9.3 0.4 2.9 2 0 0 2 2 2 0 A9 protein conserved region EzrA PF06160.12 RJW68154.1 - 0.0063 14.8 7.3 0.0094 14.2 7.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA BID PF06393.11 RJW68154.1 - 0.021 14.4 3.4 0.044 13.3 3.4 1.5 1 0 0 1 1 1 0 BH3 interacting domain (BID) NAM-associated PF14303.6 RJW68154.1 - 0.35 11.6 10.2 0.72 10.6 10.2 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain zf-C4H2 PF10146.9 RJW68154.1 - 1.2 9.4 8.7 0.11 12.7 4.0 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein Exonuc_VII_L PF02601.15 RJW68154.1 - 2.3 7.7 7.2 3.8 7.0 7.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SesA PF17107.5 RJW68154.1 - 3.1 8.0 7.2 5.9 7.1 7.2 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Apt1 PF10351.9 RJW68154.1 - 3.5 6.4 10.6 5.3 5.8 10.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sulfotransfer_4 PF17784.1 RJW68155.1 - 2e-57 194.5 0.1 2.9e-57 193.9 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW68155.1 - 1.2e-06 29.0 1.3 1.3e-05 25.7 1.3 2.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RJW68155.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain PRELI PF04707.14 RJW68157.1 - 1.6e-23 83.3 0.0 2.5e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family AhpC-TSA PF00578.21 RJW68158.1 - 6e-38 129.5 0.0 8.3e-38 129.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RJW68158.1 - 1.3e-14 54.1 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RJW68158.1 - 1.1e-12 47.6 0.0 2.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 RJW68158.1 - 0.034 14.1 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 SCO1/SenC Lectin_leg-like PF03388.13 RJW68159.1 - 3.2e-67 226.3 0.0 3.9e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 RJW68159.1 - 1.1e-07 32.1 0.0 2.2e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 RJW68159.1 - 0.0002 21.0 0.0 0.019 14.5 0.0 2.1 1 1 0 1 1 1 1 Legume lectin domain Homeodomain PF00046.29 RJW68161.1 - 5e-21 74.3 7.8 1.2e-20 73.1 7.8 1.7 1 0 0 1 1 1 1 Homeodomain Engrail_1_C_sig PF10525.9 RJW68161.1 - 4.9e-14 51.2 0.0 9.1e-14 50.4 0.0 1.5 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain CENP-B_N PF04218.13 RJW68161.1 - 0.00032 20.3 0.6 0.001 18.6 0.6 2.0 1 1 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Homeobox_KN PF05920.11 RJW68161.1 - 0.0025 17.7 0.8 0.0082 16.0 0.8 1.9 1 0 0 1 1 1 1 Homeobox KN domain DUF2244 PF10003.9 RJW68161.1 - 0.046 13.4 0.2 0.076 12.7 0.2 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Lentiviral_Tat PF02998.14 RJW68161.1 - 0.44 10.6 2.9 5.1 7.2 0.7 2.4 2 0 0 2 2 2 0 Lentiviral Tat protein Ribosomal_S6e PF01092.19 RJW68162.1 - 1.3e-58 196.4 0.0 2.3e-58 195.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e RVT_1 PF00078.27 RJW68165.1 - 4e-24 85.4 0.0 6.8e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LicD PF04991.13 RJW68166.1 - 6.7e-14 52.6 0.4 1.6e-07 31.7 0.5 2.3 1 1 0 2 2 2 2 LicD family NTP_transf_2 PF01909.23 RJW68166.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain NHL PF01436.21 RJW68168.1 - 7.6e-26 88.8 3.5 1.6e-07 31.0 0.1 5.5 5 0 0 5 5 5 5 NHL repeat DUF5128 PF17170.4 RJW68168.1 - 4.1e-15 55.8 2.9 1.6e-08 34.1 0.1 3.7 2 2 2 4 4 4 4 6-bladed beta-propeller DUF4934 PF16288.5 RJW68168.1 - 1.7e-05 24.6 0.7 0.0025 17.7 0.1 3.2 1 1 2 4 4 4 1 Domain of unknown function (DUF4934) Filamin PF00630.19 RJW68168.1 - 7e-05 23.6 0.0 0.00038 21.2 0.0 2.2 2 0 0 2 2 2 1 Filamin/ABP280 repeat SGL PF08450.12 RJW68168.1 - 0.00034 20.3 0.1 4 6.9 0.0 4.0 2 1 3 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region DUF4795 PF16043.5 RJW68168.1 - 0.057 13.0 4.3 0.088 12.4 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) SBBP PF06739.11 RJW68168.1 - 0.093 12.7 0.1 8.4 6.5 0.1 2.7 2 0 0 2 2 2 0 Beta-propeller repeat SPX PF03105.19 RJW68168.1 - 0.94 9.3 6.0 1.5 8.7 6.0 1.2 1 0 0 1 1 1 0 SPX domain SKA2 PF16740.5 RJW68168.1 - 2.5 7.9 5.9 22 4.9 1.9 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 AIP3 PF03915.13 RJW68168.1 - 4.8 6.2 8.5 6.9 5.7 8.5 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 MscS_porin PF12795.7 RJW68168.1 - 5.6 6.4 9.6 9.6 5.7 9.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Pkinase PF00069.25 RJW68170.1 - 5.8e-67 225.8 0.0 7.7e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68170.1 - 2.4e-48 164.7 0.0 3.2e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW68170.1 - 1.5e-08 34.3 0.0 3e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RJW68170.1 - 1.9e-08 33.5 0.0 3.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RJW68170.1 - 0.0022 17.0 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RJW68170.1 - 0.11 12.5 0.0 0.53 10.2 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pim PF16765.5 RJW68170.1 - 0.16 12.2 0.1 0.38 10.9 0.1 1.6 1 0 0 1 1 1 0 Pesticin immunity protein RVT_1 PF00078.27 RJW68171.1 - 4.7e-06 26.3 0.0 7.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KH_1 PF00013.29 RJW68172.1 - 2.7e-25 88.0 1.3 3.5e-12 45.9 0.1 2.5 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 RJW68172.1 - 4.3e-08 32.9 2.4 0.00011 22.0 0.6 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 RJW68172.1 - 0.0014 18.4 0.7 0.41 10.6 0.1 2.6 2 0 0 2 2 2 2 KH domain DUF3602 PF12223.8 RJW68172.1 - 0.041 14.5 1.1 0.16 12.6 1.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) SLS PF14611.6 RJW68172.1 - 0.043 13.6 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 RJW68172.1 - 0.11 12.6 2.3 11 6.2 0.2 2.4 2 0 0 2 2 2 0 NusA-like KH domain GLTP PF08718.11 RJW68173.1 - 1.5e-26 93.5 0.9 1.8e-26 93.2 0.9 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) ACP53EA PF06313.11 RJW68173.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Drosophila ACP53EA protein Tcp10_C PF07202.13 RJW68175.1 - 2.6e-59 200.1 2.3 3.7e-59 199.6 0.4 2.2 2 0 0 2 2 2 1 T-complex protein 10 C-terminus Rib PF08428.10 RJW68175.1 - 0.02 14.9 1.5 5.7 7.0 0.1 3.7 3 0 0 3 3 3 0 Rib/alpha-like repeat TetR_C_30 PF17939.1 RJW68175.1 - 0.14 12.4 2.3 2.3 8.5 0.7 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Fib_alpha PF08702.10 RJW68175.1 - 0.43 10.8 9.8 1.8 8.7 4.2 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 RJW68175.1 - 2 8.5 24.8 0.32 11.1 19.9 2.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 RJW68175.1 - 2.9 7.2 18.2 33 3.7 17.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 RJW68175.1 - 3.6 8.1 30.8 2.9 8.4 16.8 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region FUSC PF04632.12 RJW68175.1 - 5.2 5.5 6.7 8.4 4.8 6.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 RJW68175.1 - 5.7 6.2 19.8 2.1 7.6 6.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF5082 PF16888.5 RJW68175.1 - 8.3 6.7 18.8 0.71 10.2 0.7 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) TMF_DNA_bd PF12329.8 RJW68175.1 - 8.8 6.4 23.2 0.022 14.7 5.8 3.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2852 PF11014.8 RJW68175.1 - 9.3 6.4 15.7 23 5.2 12.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) DivIC PF04977.15 RJW68175.1 - 9.8 6.0 19.8 0.049 13.4 4.3 4.0 2 1 0 3 3 3 0 Septum formation initiator Methyltransf_5 PF01795.19 RJW68176.1 - 2.3e-88 296.7 0.0 1.6e-83 280.8 0.0 2.0 1 1 1 2 2 2 2 MraW methylase family HHH_3 PF12836.7 RJW68176.1 - 0.013 15.8 0.1 0.042 14.1 0.1 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif KRAP_IP3R_bind PF14722.6 RJW68176.1 - 0.014 15.1 0.0 7 6.4 0.0 2.4 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Methyltr_RsmB-F PF01189.17 RJW68176.1 - 0.017 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 RJW68176.1 - 0.024 15.4 0.0 0.11 13.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain SlyX PF04102.12 RJW68178.1 - 0.096 13.3 0.1 0.43 11.2 0.1 2.2 1 0 0 1 1 1 0 SlyX CoA_binding PF02629.19 RJW68181.1 - 4.6e-31 107.4 0.1 9.8e-31 106.3 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 RJW68181.1 - 1.6e-22 80.0 0.0 3.5e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 RJW68181.1 - 1.7e-08 34.4 0.0 4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 RJW68181.1 - 0.0016 18.9 0.0 0.0033 17.9 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain Nrap_D4 PF17405.2 RJW68182.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Nrap protein nucleotidyltransferase domain 4 Pkinase PF00069.25 RJW68183.1 - 2.8e-68 230.2 0.0 4e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68183.1 - 6.3e-53 179.7 0.0 9.2e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW68183.1 - 1.3e-05 24.7 0.0 6.2e-05 22.4 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RJW68183.1 - 2.7e-05 23.1 0.0 4.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RJW68183.1 - 0.0026 17.7 1.1 0.012 15.5 0.2 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 RJW68183.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 RJW68183.1 - 0.053 12.6 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MARVEL PF01284.23 RJW68184.1 - 1.1e-22 80.6 9.4 1.7e-22 80.0 9.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain RVT_1 PF00078.27 RJW68184.1 - 2.7e-16 59.8 0.0 4.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_holin_3_6 PF07332.11 RJW68184.1 - 0.15 12.1 2.0 0.16 12.0 0.3 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3566 PF12089.8 RJW68184.1 - 1.5 9.2 4.8 0.64 10.4 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) UBA_4 PF14555.6 RJW68186.1 - 6.4e-13 48.3 0.3 1.1e-12 47.5 0.3 1.4 1 0 0 1 1 1 1 UBA-like domain N_BRCA1_IG PF16158.5 RJW68186.1 - 0.0049 17.6 0.0 0.012 16.4 0.0 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene Pkinase PF00069.25 RJW68187.1 - 3.9e-65 219.8 0.0 7e-65 219.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68187.1 - 2.1e-44 151.7 0.0 3.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 RJW68187.1 - 5.9e-10 39.4 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 RJW68187.1 - 6.5e-09 35.5 0.0 1.9e-07 30.7 0.0 2.6 2 1 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 RJW68187.1 - 6.8e-08 31.7 0.3 1.6e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 RJW68187.1 - 0.0098 14.9 2.0 0.054 12.4 0.3 2.4 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 RJW68187.1 - 0.018 14.6 0.0 0.66 9.6 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PX PF00787.24 RJW68188.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 PX domain Trypsin PF00089.26 RJW68189.1 - 1.1e-65 221.5 0.0 1.5e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 RJW68189.1 - 3.3e-13 49.9 0.1 5.5e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 CUB domain Trypsin_2 PF13365.6 RJW68189.1 - 9.9e-05 23.3 0.0 0.0002 22.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 RJW68189.1 - 0.00036 20.9 0.0 0.00082 19.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Peptidase_S6 PF02395.16 RJW68189.1 - 0.32 9.0 0.0 0.44 8.5 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease MRP-L46 PF11788.8 RJW68191.1 - 0.0001 23.0 0.2 0.00018 22.2 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 HEAT PF02985.22 RJW68193.1 - 9.3e-08 31.7 1.6 2.2 8.8 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat CLASP_N PF12348.8 RJW68193.1 - 0.0002 21.0 6.2 0.41 10.2 0.1 4.2 4 1 0 4 4 4 2 CLASP N terminal HEAT_2 PF13646.6 RJW68193.1 - 0.00064 20.1 6.9 3.6 8.1 0.0 6.3 7 1 1 8 8 8 1 HEAT repeats HEAT_EZ PF13513.6 RJW68193.1 - 0.11 13.1 3.5 10 6.8 0.1 5.0 4 0 0 4 4 4 0 HEAT-like repeat RR_TM4-6 PF06459.12 RJW68193.1 - 7.6 6.3 7.2 19 4.9 7.2 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sulfotransfer_4 PF17784.1 RJW68195.1 - 9.7e-40 136.7 0.0 2e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW68195.1 - 0.00027 21.4 0.1 0.00081 19.8 0.1 1.9 1 0 0 1 1 1 1 Sulfotransferase family SprA-related PF12118.8 RJW68195.1 - 0.23 10.6 14.2 0.49 9.5 14.2 1.5 1 0 0 1 1 1 0 SprA-related family Exo_endo_phos PF03372.23 RJW68197.1 - 1.6e-08 34.3 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RJW68197.1 - 0.0051 16.6 0.1 0.016 15.1 0.1 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase CDC50 PF03381.15 RJW68199.1 - 5e-81 272.3 0.0 7.3e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RVT_1 PF00078.27 RJW68200.1 - 1.3e-46 158.9 0.1 2.8e-46 157.8 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMADHC PF10229.9 RJW68200.1 - 1e-33 117.3 0.0 2.3e-33 116.1 0.0 1.5 2 0 0 2 2 2 1 Methylmalonic aciduria and homocystinuria type D protein Pkinase PF00069.25 RJW68202.1 - 3.3e-11 43.1 0.0 4.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68202.1 - 2.6e-07 30.2 0.2 7.2e-07 28.7 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1851 PF08906.11 RJW68202.1 - 0.091 12.7 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1851) HLH PF00010.26 RJW68204.1 - 5.3e-10 39.1 0.2 9.6e-10 38.3 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TPR_2 PF07719.17 RJW68205.1 - 1.1e-13 50.2 16.7 0.0013 18.7 0.2 10.3 12 1 1 13 13 12 3 Tetratricopeptide repeat TPR_14 PF13428.6 RJW68205.1 - 2.2e-13 49.8 18.6 0.15 13.0 0.1 8.7 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 RJW68205.1 - 4.5e-13 49.5 14.0 0.00011 22.7 0.2 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 RJW68205.1 - 2.2e-12 46.5 6.9 0.49 10.9 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 RJW68205.1 - 1.4e-10 40.5 12.9 0.00018 21.5 0.2 8.5 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 RJW68205.1 - 1.9e-10 40.3 1.4 0.01 15.5 0.1 6.1 7 1 1 8 8 7 2 TPR repeat TPR_1 PF00515.28 RJW68205.1 - 3.9e-09 36.0 11.9 0.013 15.3 0.6 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW68205.1 - 3e-08 34.2 21.6 0.0024 18.5 0.0 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW68205.1 - 7.7e-08 32.4 17.2 0.022 15.0 0.8 6.2 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RJW68205.1 - 7.1e-06 26.2 19.0 0.016 15.5 0.4 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW68205.1 - 0.0011 18.4 11.0 0.13 11.6 1.7 3.6 3 1 0 3 3 3 2 MalT-like TPR region TPPII_N PF12583.8 RJW68205.1 - 0.0012 19.5 0.1 0.0025 18.4 0.1 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal TPR_6 PF13174.6 RJW68205.1 - 0.0022 18.5 4.2 2.2 9.1 0.0 5.6 5 0 0 5 5 4 1 Tetratricopeptide repeat PknG_TPR PF16918.5 RJW68205.1 - 0.0042 15.9 0.7 0.0094 14.7 0.2 1.7 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_21 PF09976.9 RJW68205.1 - 0.043 13.5 0.5 0.42 10.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain ChAPs PF09295.10 RJW68205.1 - 0.11 11.5 0.3 6.3 5.7 0.1 3.1 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 RJW68205.1 - 0.47 10.8 5.1 28 5.2 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_10 PF17902.1 RJW68206.1 - 0.00094 19.2 0.2 0.35 11.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain Rop-like PF05082.13 RJW68206.1 - 0.035 13.9 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 Rop-like RLL PF10036.9 RJW68207.1 - 1.3e-69 234.9 0.0 1.5e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Not3 PF04065.15 RJW68208.1 - 1.1e-79 267.1 26.8 1.5e-79 266.7 26.8 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 RJW68208.1 - 5e-35 120.4 7.5 5e-35 120.4 7.5 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF4164 PF13747.6 RJW68208.1 - 1.1 9.5 12.6 0.12 12.7 5.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Exo_endo_phos PF03372.23 RJW68209.1 - 7.8e-10 38.7 0.0 8.9e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SH3_10 PF17902.1 RJW68211.1 - 3.3e-07 30.3 0.0 0.014 15.4 0.0 2.7 2 0 0 2 2 2 2 SH3 domain T4bSS_IcmS PF12608.8 RJW68212.1 - 0.053 13.8 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment PseudoU_synth_2 PF00849.22 RJW68213.1 - 1.1e-28 100.4 0.0 3.5e-28 98.7 0.0 1.9 2 1 0 2 2 2 1 RNA pseudouridylate synthase Tmemb_cc2 PF10267.9 RJW68213.1 - 0.11 11.6 1.1 0.17 11.0 0.4 1.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein PH_17 PF18012.1 RJW68213.1 - 2 8.2 0.0 2 8.2 0.0 2.9 4 0 0 4 4 4 0 PH domain Pkinase PF00069.25 RJW68214.1 - 1.5e-26 93.3 0.0 1.6e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68214.1 - 1e-09 38.1 0.0 1.1e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW68214.1 - 2.2e-05 23.9 0.0 2.4e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RJW68214.1 - 0.0013 18.1 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RJW68214.1 - 0.0045 15.8 0.0 0.0048 15.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 RJW68214.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 RJW68214.1 - 0.17 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 RJW68215.1 - 2e-38 132.3 0.0 2.4e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68215.1 - 3.2e-16 59.4 0.0 4.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW68215.1 - 3.2e-07 29.5 0.0 5.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW68215.1 - 0.00065 19.1 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RJW68215.1 - 0.046 13.1 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 RJW68215.1 - 0.2 10.6 0.1 0.36 9.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UPF0020 PF01170.18 RJW68217.1 - 1.8e-12 47.3 0.0 2.7e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 RJW68217.1 - 0.0025 18.5 0.1 0.012 16.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RJW68217.1 - 0.17 12.6 0.0 0.44 11.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain HSD3 PF15244.6 RJW68218.1 - 3.5e-22 79.5 21.2 1.5e-10 41.2 1.9 3.8 2 1 2 4 4 4 3 Spermatogenesis-associated protein 7, or HSD3 Ima1_N PF09779.9 RJW68219.1 - 1.3e-28 100.6 2.7 1.3e-28 100.6 2.7 1.9 2 0 0 2 2 2 1 Ima1 N-terminal domain zf-RRPl_C4 PF17026.5 RJW68219.1 - 0.0016 18.5 2.0 0.0084 16.2 2.0 2.3 1 1 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type LANC_like PF05147.13 RJW68220.1 - 0.12 10.9 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Lectin_C PF00059.21 RJW68221.1 - 3.4e-08 34.2 1.5 3.9e-08 34.0 0.1 1.8 2 0 0 2 2 2 1 Lectin C-type domain DUF155 PF02582.14 RJW68222.1 - 1.2e-43 149.2 0.1 2.6e-43 148.1 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Metallophos PF00149.28 RJW68222.1 - 3e-11 44.2 1.6 4.9e-11 43.5 1.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Filament PF00038.21 RJW68223.1 - 6.7e-51 173.7 63.3 1.4e-50 172.7 63.3 1.5 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 RJW68223.1 - 1.2e-12 48.2 0.0 2.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain Tup_N PF08581.10 RJW68223.1 - 0.00065 20.0 9.8 0.00065 20.0 9.8 5.7 2 2 3 5 5 5 2 Tup N-terminal DUF3137 PF11335.8 RJW68223.1 - 0.021 14.7 1.6 0.057 13.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) DUF4094 PF13334.6 RJW68223.1 - 0.025 15.0 2.8 0.025 15.0 2.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Pox_A_type_inc PF04508.12 RJW68223.1 - 0.7 9.9 23.9 0.19 11.6 1.9 5.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Bacillus_HBL PF05791.11 RJW68223.1 - 0.85 9.4 12.7 1 9.2 1.7 2.8 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Tektin PF03148.14 RJW68223.1 - 0.9 8.2 45.6 13 4.4 45.5 2.6 1 1 0 1 1 1 0 Tektin family FAM184 PF15665.5 RJW68223.1 - 8.2 6.1 52.5 4.3 7.1 5.6 4.0 1 1 3 4 4 4 0 Family with sequence similarity 184, A and B Vps54 PF07928.12 RJW68225.1 - 6.8e-38 130.1 0.3 4.4e-37 127.5 0.0 2.5 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 RJW68225.1 - 1.3e-09 37.8 5.2 1.3e-09 37.8 5.2 2.6 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 RJW68225.1 - 0.00026 20.9 3.3 0.00026 20.9 0.9 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain TMV_coat PF00721.21 RJW68225.1 - 0.036 13.9 0.2 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 Virus coat protein (TMV like) DUF2333 PF10095.9 RJW68225.1 - 0.18 10.8 0.7 0.4 9.6 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) MCLC PF05934.11 RJW68227.1 - 0.036 12.8 0.0 0.036 12.8 0.0 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Tissue_fac PF01108.17 RJW68228.1 - 0.066 13.1 0.1 0.083 12.7 0.1 1.3 1 0 0 1 1 1 0 Tissue factor rve PF00665.26 RJW68229.1 - 9.2e-16 58.1 0.0 2.3e-15 56.8 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 RJW68229.1 - 0.00015 21.4 0.5 0.00059 19.6 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain DUF2691 PF10903.8 RJW68230.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) Maf PF02545.14 RJW68232.1 - 1.1e-54 184.7 0.0 1.2e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein CAP160 PF07918.11 RJW68232.1 - 0.36 10.6 2.8 0.87 9.4 2.8 1.6 1 0 0 1 1 1 0 CAP160 repeat Acatn PF13000.7 RJW68234.1 - 5.2e-112 375.1 7.1 1.9e-74 251.1 2.3 3.2 2 1 0 2 2 2 2 Acetyl-coenzyme A transporter 1 Pkinase PF00069.25 RJW68235.1 - 5.3e-25 88.3 0.0 1.6e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68235.1 - 1.3e-10 41.0 0.0 4.8e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase C1q PF00386.21 RJW68236.1 - 0.019 15.2 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 C1q domain DUF4507 PF14964.6 RJW68238.1 - 3.6e-10 39.3 5.9 6.2e-09 35.2 5.9 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4507) DUF4476 PF14771.6 RJW68239.1 - 1.6e-10 41.1 0.2 1.4e-06 28.5 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4476) MTS PF05175.14 RJW68239.1 - 0.063 12.8 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain MoeA_N PF03453.17 RJW68239.1 - 0.15 11.8 0.2 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 MoeA N-terminal region (domain I and II) Ran_BP1 PF00638.18 RJW68240.1 - 1.5e-08 34.9 0.0 0.00012 22.4 0.0 3.1 3 0 0 3 3 3 2 RanBP1 domain GP4 PF03010.14 RJW68241.1 - 0.017 15.0 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 GP4 Ldl_recept_a PF00057.18 RJW68244.1 - 3.6e-45 151.9 88.7 3.8e-11 43.0 11.0 7.7 7 0 0 7 7 7 6 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 RJW68244.1 - 4.1e-07 30.2 6.8 4.1e-07 30.2 6.8 5.2 4 1 1 5 5 5 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 RJW68244.1 - 0.0013 18.9 3.9 0.0013 18.9 3.9 6.3 6 4 0 6 6 6 1 EGF domain RVT_1 PF00078.27 RJW68246.1 - 6.6e-05 22.5 0.0 9.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTB PF00651.31 RJW68247.1 - 3.2e-20 72.4 0.2 2.2e-18 66.5 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain Na_H_Exchanger PF00999.21 RJW68249.1 - 2.2e-13 49.8 42.9 2.8e-07 29.7 6.6 3.2 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family GST_C_2 PF13410.6 RJW68251.1 - 1.5e-07 31.3 0.0 2.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RJW68251.1 - 0.0018 18.4 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RJW68251.1 - 0.011 15.9 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HupH_C PF04809.13 RJW68254.1 - 0.028 14.1 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region Ribosomal_L22 PF00237.19 RJW68255.1 - 1.5e-12 47.6 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e WD40 PF00400.32 RJW68257.1 - 2.7e-18 66.0 13.7 0.0022 18.8 0.3 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW68257.1 - 2.3e-06 27.8 0.1 1.2 9.5 0.0 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW68257.1 - 0.027 13.5 0.1 0.17 10.8 0.0 2.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RJW68257.1 - 0.039 12.6 0.7 3.7 6.1 0.1 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 UFC1 PF08694.11 RJW68258.1 - 7.7e-60 201.0 0.1 2.5e-47 160.4 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 RJW68258.1 - 0.06 13.6 0.0 0.069 13.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain C1q PF00386.21 RJW68260.1 - 0.067 13.4 0.3 0.75 10.0 0.0 2.0 2 0 0 2 2 2 0 C1q domain Peptidase_M17 PF00883.21 RJW68263.1 - 5.5e-56 190.1 0.0 7e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Ribosomal_L6e PF01159.19 RJW68265.1 - 4.9e-35 120.4 0.5 4.9e-35 120.4 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e DUF3274 PF11678.8 RJW68265.1 - 1 8.6 3.9 0.22 10.7 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3274) Nepo_coat_N PF03689.15 RJW68266.1 - 0.0045 16.9 1.7 0.011 15.6 0.1 2.1 2 0 0 2 2 2 1 Nepovirus coat protein, N-terminal domain AAA_11 PF13086.6 RJW68266.1 - 5.6 6.7 10.4 7.2 6.3 10.4 1.1 1 0 0 1 1 1 0 AAA domain PDZ PF00595.24 RJW68267.1 - 5.7e-23 81.1 0.0 1.8e-13 50.6 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RJW68267.1 - 8.6e-20 70.3 0.0 7e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RJW68267.1 - 9.8e-10 38.6 0.0 0.0002 21.6 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Phage_rep_O PF04492.13 RJW68267.1 - 0.1 13.2 0.2 0.33 11.6 0.2 1.8 1 0 0 1 1 1 0 Bacteriophage replication protein O zf-P11 PF03854.14 RJW68267.1 - 2.8 7.7 10.3 4.8 6.9 0.1 2.6 2 0 0 2 2 2 0 P-11 zinc finger Chromo PF00385.24 RJW68268.1 - 1.3e-11 44.2 0.0 2.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SpoVAD PF07451.11 RJW68268.1 - 0.041 12.6 0.1 0.066 11.9 0.1 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) UPF0302 PF08864.10 RJW68268.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 UPF0302 domain PT PF04886.12 RJW68271.1 - 4.9e-18 64.4 14.5 35 4.1 14.5 6.4 1 1 0 1 1 1 1 PT repeat Pox_E10 PF04805.12 RJW68271.1 - 0.1 12.5 1.1 0.14 12.0 0.3 1.6 2 0 0 2 2 2 0 E10-like protein conserved region RelE PF06296.12 RJW68272.1 - 0.09 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system DSPc PF00782.20 RJW68273.1 - 5e-32 110.5 0.0 7.5e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RJW68273.1 - 0.0025 17.4 0.1 0.0043 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase NCOA_u2 PF16665.5 RJW68273.1 - 3.5 8.0 7.8 0.32 11.3 1.7 2.4 2 0 0 2 2 2 0 Unstructured region on nuclear receptor coactivator protein Pkinase PF00069.25 RJW68274.1 - 2.8e-63 213.8 0.0 3.8e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68274.1 - 3.6e-51 173.9 0.0 5.1e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW68274.1 - 0.0001 21.7 0.0 0.00023 20.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RJW68274.1 - 0.00013 20.9 0.0 0.00025 20.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RJW68274.1 - 0.00018 20.6 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RJW68274.1 - 0.0055 16.1 0.1 0.0096 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 RJW68274.1 - 0.088 12.4 0.0 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 YEATS PF03366.16 RJW68275.1 - 7.1e-31 106.0 0.6 1.4e-30 105.1 0.6 1.5 1 0 0 1 1 1 1 YEATS family DUF3160 PF11369.8 RJW68275.1 - 0.03 12.8 0.1 0.043 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) SBDS_C PF09377.10 RJW68275.1 - 0.064 13.3 0.3 0.48 10.5 0.2 2.1 2 0 0 2 2 2 0 SBDS protein C-terminal domain RuBisCO_small PF00101.20 RJW68276.1 - 0.094 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain MULE PF10551.9 RJW68277.1 - 0.00046 20.6 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain zf-C3H2C3 PF17122.5 RJW68277.1 - 0.0055 16.7 0.6 0.02 14.9 0.6 2.1 1 0 0 1 1 1 1 Zinc-finger SWIM PF04434.17 RJW68277.1 - 0.64 9.7 7.5 0.84 9.4 0.6 2.8 2 1 1 3 3 3 0 SWIM zinc finger Zip PF02535.22 RJW68278.1 - 1.6e-85 287.3 5.6 1.5e-59 201.9 2.8 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter Presenilin PF01080.17 RJW68278.1 - 0.016 14.0 0.7 3.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Presenilin FA_desaturase PF00487.24 RJW68278.1 - 0.32 10.8 2.4 13 5.5 0.3 2.3 2 0 0 2 2 2 0 Fatty acid desaturase HA PF03457.14 RJW68279.1 - 0.052 13.9 0.3 0.059 13.7 0.3 1.2 1 0 0 1 1 1 0 Helicase associated domain Nipped-B_C PF12830.7 RJW68280.1 - 5.1e-62 209.2 0.9 2.4e-61 207.0 0.0 2.8 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 RJW68280.1 - 0.0003 21.0 5.2 0.00092 19.5 0.8 4.0 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 RJW68280.1 - 0.0067 16.5 2.9 0.34 10.9 0.0 3.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RJW68280.1 - 0.079 13.5 4.2 0.85 10.2 0.2 4.6 5 1 1 6 6 6 0 HEAT-like repeat HEAT PF02985.22 RJW68280.1 - 0.37 11.2 5.0 8.8 6.9 0.2 4.9 5 0 0 5 5 5 0 HEAT repeat FrhB_FdhB_C PF04432.13 RJW68282.1 - 0.023 14.5 0.3 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Ephrin_rec_like PF07699.13 RJW68282.1 - 0.024 14.4 2.2 0.084 12.6 2.2 1.9 1 0 0 1 1 1 0 Putative ephrin-receptor like Adaptin_binding PF10199.9 RJW68282.1 - 0.078 13.6 2.7 0.65 10.6 2.4 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Rdx PF10262.9 RJW68282.1 - 0.087 13.0 0.0 0.39 10.9 0.0 2.1 1 0 0 1 1 1 0 Rdx family Spc7 PF08317.11 RJW68282.1 - 2 7.2 12.3 3.7 6.3 12.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein MIP-T3_C PF17749.1 RJW68282.1 - 2.6 8.0 9.7 3.3 7.7 7.5 2.1 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region OmpH PF03938.14 RJW68282.1 - 3.8 7.8 9.3 9.8 6.5 9.3 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Integrin_beta PF00362.18 RJW68283.1 - 4.1e-91 305.1 0.0 6.2e-91 304.5 0.0 1.3 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 RJW68283.1 - 1.8e-18 65.9 0.2 3.6e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain EGF_2 PF07974.13 RJW68283.1 - 1.4e-15 57.4 77.5 2.1e-05 24.8 15.2 5.7 4 0 0 4 4 4 4 EGF-like domain I-EGF_1 PF18372.1 RJW68283.1 - 1.8e-05 24.7 24.4 4e-05 23.6 4.8 6.0 6 0 0 6 6 6 3 Integrin beta epidermal growth factor like domain 1 EGF_Tenascin PF18720.1 RJW68283.1 - 0.0015 18.5 9.3 0.0015 18.5 9.3 4.9 4 0 0 4 4 4 2 Tenascin EGF domain Ribosomal_L14 PF00238.19 RJW68284.1 - 6.6e-37 126.3 0.1 8.2e-37 126.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Thg1 PF04446.12 RJW68285.1 - 3.1e-46 156.5 0.1 5e-46 155.8 0.1 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 RJW68285.1 - 6.8e-43 145.7 0.9 1.4e-42 144.7 0.9 1.5 1 0 0 1 1 1 1 Thg1 C terminal domain OGG_N PF07934.12 RJW68285.1 - 7.6e-23 80.9 0.0 1.8e-21 76.4 0.0 2.4 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 RJW68285.1 - 3.2e-10 40.4 0.0 6.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Nodulin_late PF07127.11 RJW68285.1 - 0.072 13.4 0.4 0.23 11.8 0.4 1.8 1 0 0 1 1 1 0 Late nodulin protein HHH PF00633.23 RJW68285.1 - 0.083 12.8 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif RNA_pol_Rpb4 PF03874.16 RJW68286.1 - 2.1e-20 73.3 3.0 3.8e-20 72.5 3.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 PDT PF00800.18 RJW68286.1 - 0.083 12.7 0.4 0.097 12.5 0.4 1.3 1 1 0 1 1 1 0 Prephenate dehydratase RVT_1 PF00078.27 RJW68287.1 - 5.8e-11 42.3 0.0 1.4e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4541 PF15074.6 RJW68288.1 - 8.2e-05 23.1 0.2 0.00015 22.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) FAM183 PF14886.6 RJW68288.1 - 0.0019 18.9 3.0 0.0042 17.8 1.2 2.4 1 1 0 1 1 1 1 FAM183A and FAM183B related SH3_9 PF14604.6 RJW68289.1 - 9.8e-21 73.4 0.2 1.3e-10 40.9 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 RJW68289.1 - 1.9e-19 69.1 0.0 1.4e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 RJW68289.1 - 3.1e-11 42.7 0.9 2.5e-05 23.8 0.1 3.1 2 2 0 2 2 2 2 SH3 domain WD40 PF00400.32 RJW68290.1 - 2.8e-36 122.9 25.0 3.2e-08 34.1 0.9 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 RJW68290.1 - 8.9e-34 116.5 1.7 1.4e-33 115.9 1.7 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 RJW68290.1 - 9.7e-13 48.2 0.0 0.01 16.1 0.0 5.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW68290.1 - 0.013 15.4 0.0 0.17 11.8 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 RJW68290.1 - 0.037 13.4 0.2 3.1 7.0 0.0 3.2 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 RJW68290.1 - 0.11 11.1 0.4 11 4.5 0.1 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 zf-C2HC_2 PF13913.6 RJW68291.1 - 4.5 7.3 6.7 5.7 7.0 0.7 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SH3_9 PF14604.6 RJW68293.1 - 2.5e-13 49.6 0.1 4.3e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain LIM PF00412.22 RJW68293.1 - 1.4e-12 47.6 8.8 3e-12 46.6 8.8 1.6 1 0 0 1 1 1 1 LIM domain SH3_1 PF00018.28 RJW68293.1 - 1e-11 44.2 0.0 1.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Nebulin PF00880.18 RJW68293.1 - 2.4e-06 27.3 0.0 4.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Nebulin repeat SH3_2 PF07653.17 RJW68293.1 - 3.2e-05 23.5 0.0 6.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain 2OG-FeII_Oxy_2 PF13532.6 RJW68294.1 - 0.001 19.3 0.0 0.018 15.2 0.0 2.3 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Kelch_1 PF01344.25 RJW68296.1 - 4.5e-22 77.4 2.5 1.3e-06 27.8 0.0 6.3 6 0 0 6 6 6 5 Kelch motif BTB PF00651.31 RJW68296.1 - 4.8e-08 33.2 0.0 9.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 RJW68296.1 - 2.7e-07 30.7 2.4 0.33 11.3 0.0 5.1 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 RJW68296.1 - 9e-07 28.6 0.4 0.85 9.7 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 RJW68296.1 - 6.7e-05 23.1 9.5 0.045 14.1 0.4 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.6 RJW68296.1 - 0.0047 16.9 5.8 0.3 11.1 0.1 4.4 5 0 0 5 5 5 1 Galactose oxidase, central domain DUF393 PF04134.12 RJW68297.1 - 0.042 15.2 0.8 0.082 14.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF393 Peptidase_C2 PF00648.21 RJW68298.1 - 6.1e-61 206.0 0.0 8e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Trypan_PARP PF05887.11 RJW68299.1 - 0.29 11.1 11.5 0.31 11.0 11.5 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PRP38_assoc PF12871.7 RJW68299.1 - 2.1 9.0 48.1 7 7.3 48.1 1.7 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 PF13054.6 RJW68299.1 - 3.1 7.8 44.3 1.8e+04 -10.1 44.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) T-box_assoc PF16176.5 RJW68300.1 - 0.00046 20.3 6.6 0.22 11.6 0.5 2.8 1 1 3 4 4 4 4 T-box transcription factor-associated Metallothio_Euk PF12749.7 RJW68300.1 - 0.23 11.6 12.4 14 6.0 2.3 3.3 1 1 2 3 3 3 0 Eukaryotic metallothionein DUF1241 PF06840.11 RJW68301.1 - 7.7e-46 155.5 0.2 1e-45 155.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) DUF3038 PF11237.8 RJW68301.1 - 0.0099 15.9 3.8 0.014 15.5 3.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3038) Focal_AT PF03623.13 RJW68301.1 - 0.017 15.1 0.5 0.046 13.7 0.5 1.9 1 1 1 2 2 2 0 Focal adhesion targeting region Spore_III_AB PF09548.10 RJW68301.1 - 0.02 15.0 0.6 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Med11 PF10280.9 RJW68301.1 - 0.045 14.2 0.8 0.087 13.3 0.8 1.4 1 0 0 1 1 1 0 Mediator complex protein Rogdi_lz PF10259.9 RJW68301.1 - 0.082 12.3 0.6 0.098 12.1 0.6 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Talin_middle PF09141.10 RJW68301.1 - 0.1 12.6 1.6 0.23 11.5 1.1 1.8 2 0 0 2 2 2 0 Talin, middle domain Cwf_Cwc_15 PF04889.12 RJW68304.1 - 0.15 11.8 5.6 0.23 11.1 5.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 RJW68304.1 - 3.9 7.9 10.9 8.4 6.9 10.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 RJW68304.1 - 4.3 6.4 8.4 6 5.9 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DLH PF01738.18 RJW68305.1 - 1e-13 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 RJW68306.1 - 6.6e-14 52.0 0.0 8.7e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Rad51 PF08423.11 RJW68307.1 - 1.1e-91 306.7 0.0 1.2e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 RJW68307.1 - 3.2e-06 26.8 0.0 4.7e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RJW68307.1 - 0.0082 16.4 0.1 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain ssDNA_TraI_N PF18272.1 RJW68307.1 - 0.038 14.0 0.1 0.085 12.9 0.1 1.6 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain Rad51 PF08423.11 RJW68308.1 - 9e-30 103.8 0.6 1.3e-29 103.2 0.6 1.2 1 0 0 1 1 1 1 Rad51 HHH_5 PF14520.6 RJW68308.1 - 1.4e-06 28.8 1.5 2.9e-06 27.8 1.5 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 RJW68308.1 - 0.00014 21.3 0.1 0.00021 20.7 0.1 1.2 1 0 0 1 1 1 1 KaiC RecA PF00154.21 RJW68308.1 - 0.00052 19.6 0.0 0.00072 19.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HhH-GPD PF00730.25 RJW68308.1 - 0.042 14.3 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RJW68308.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Laminin_G_2 PF02210.24 RJW68309.1 - 1e-33 116.6 1.6 3.9e-17 63.0 0.1 2.4 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 RJW68309.1 - 2e-24 86.3 0.0 1.1e-13 51.5 0.0 2.5 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 RJW68309.1 - 0.00011 22.4 2.7 0.00047 20.4 0.9 2.6 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 RJW68309.1 - 0.061 13.7 4.1 0.17 12.3 4.1 1.8 1 0 0 1 1 1 0 EGF-like domain SPRY PF00622.28 RJW68310.1 - 1.7e-08 34.6 0.0 4.6e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.21 RJW68310.1 - 0.00095 19.5 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW68310.1 - 0.098 13.2 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain 7tm_1 PF00001.21 RJW68313.1 - 2e-07 30.6 21.5 2e-07 30.6 21.5 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Sdh_cyt PF01127.22 RJW68313.1 - 0.078 13.0 0.1 0.078 13.0 0.1 2.7 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Glyco_hydro_8 PF01270.17 RJW68316.1 - 0.0048 15.8 0.0 0.0068 15.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 DUF413 PF04219.12 RJW68317.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF Homeodomain PF00046.29 RJW68318.1 - 2.6e-21 75.2 2.8 5.3e-21 74.2 2.8 1.6 1 0 0 1 1 1 1 Homeodomain Ig_3 PF13927.6 RJW68319.1 - 2.7e-07 31.1 0.2 0.038 14.6 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RJW68319.1 - 2e-05 24.7 0.2 0.021 15.0 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 RJW68319.1 - 3.1e-05 24.1 2.4 0.021 15.0 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RJW68319.1 - 0.00068 19.7 0.1 0.046 13.8 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_5 PF16681.5 RJW68319.1 - 0.0025 18.2 2.7 6.1 7.3 0.9 4.1 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 RJW68319.1 - 0.016 14.8 0.2 4.4 7.0 0.1 2.8 2 0 0 2 2 2 0 Immunoglobulin domain Transglut_N PF00868.20 RJW68320.1 - 0.029 14.7 0.0 0.067 13.5 0.0 1.5 1 1 0 1 1 1 0 Transglutaminase family E1_DerP2_DerF2 PF02221.15 RJW68320.1 - 0.063 13.7 0.2 0.091 13.2 0.2 1.2 1 0 0 1 1 1 0 ML domain TTL PF03133.15 RJW68321.1 - 3.4e-38 131.4 0.0 4e-30 105.0 0.0 2.5 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RJW68321.1 - 0.0012 18.2 0.0 1.4 8.1 0.0 2.9 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RJW68321.1 - 0.072 12.3 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp PAS_3 PF08447.12 RJW68322.1 - 0.002 18.4 0.0 0.0097 16.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold 4F5 PF04419.14 RJW68323.1 - 1.2e-10 42.0 10.7 1.9e-10 41.4 10.7 1.2 1 0 0 1 1 1 1 4F5 protein family DUF629 PF04780.12 RJW68323.1 - 0.015 13.9 0.8 0.017 13.7 0.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF629) zf-met PF12874.7 RJW68323.1 - 0.015 15.6 0.5 0.031 14.7 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_12 PF18658.1 RJW68323.1 - 0.029 13.9 0.1 0.043 13.4 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-C2H2_2 PF12756.7 RJW68323.1 - 0.038 14.3 2.2 0.045 14.1 1.7 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) TALPID3 PF15324.6 RJW68323.1 - 0.051 11.3 4.0 0.056 11.1 4.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target ARD PF03079.14 RJW68323.1 - 0.076 13.2 1.2 0.081 13.1 1.2 1.1 1 0 0 1 1 1 0 ARD/ARD' family zf-met2 PF12907.7 RJW68323.1 - 0.09 12.9 6.3 0.4 10.9 6.3 2.0 1 1 0 1 1 1 0 Zinc-binding zf-C2H2_4 PF13894.6 RJW68323.1 - 0.099 13.5 2.4 0.18 12.8 2.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.6 RJW68332.1 - 2.4e-07 30.5 2.6 2.4e-07 30.5 2.6 4.5 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RJW68332.1 - 7.3e-07 29.3 4.6 7.3e-07 29.3 4.6 4.5 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RJW68332.1 - 1.8e-06 27.9 4.0 1.8e-06 27.9 4.0 4.9 4 2 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RJW68332.1 - 3.1e-05 23.8 2.2 3.1e-05 23.8 2.2 4.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 RJW68332.1 - 3.7e-05 23.8 21.1 0.00049 20.2 9.0 5.2 6 0 0 6 6 6 2 B-box zinc finger zf-RING_5 PF14634.6 RJW68332.1 - 4e-05 23.5 3.0 4e-05 23.5 3.0 6.0 5 2 1 6 6 6 1 zinc-RING finger domain zf-RING_2 PF13639.6 RJW68332.1 - 0.024 15.0 6.0 0.024 15.0 6.0 5.0 4 0 0 4 4 4 0 Ring finger domain IBR PF01485.21 RJW68332.1 - 0.18 12.0 36.1 1.5 9.1 1.2 4.8 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain 7tm_1 PF00001.21 RJW68334.1 - 1.2e-07 31.3 9.0 1.2e-07 31.3 9.0 2.3 1 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF382 PF04037.13 RJW68335.1 - 1.3e-58 196.7 1.0 1.3e-58 196.7 1.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 RJW68335.1 - 2.6e-05 24.0 0.2 6.5e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 PSP SH3_10 PF17902.1 RJW68338.1 - 0.0017 18.4 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain zf-C2H2 PF00096.26 RJW68340.1 - 6.9e-14 51.4 20.2 0.0002 21.6 3.1 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW68340.1 - 6.5e-13 48.5 20.2 2.4e-07 30.9 0.8 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW68340.1 - 3e-07 30.7 19.2 0.011 16.5 2.4 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 RJW68340.1 - 0.073 13.7 0.7 0.073 13.7 0.7 2.8 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 RJW68340.1 - 2.9 8.3 5.3 20 5.6 5.0 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TPR_2 PF07719.17 RJW68341.1 - 2.9e-10 39.4 15.5 0.25 11.5 0.7 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 RJW68341.1 - 6.5e-08 32.8 25.0 1.2 10.1 0.1 8.8 9 2 1 10 10 7 4 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 RJW68341.1 - 2.4e-07 30.9 1.0 0.016 15.4 0.1 5.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PPR PF01535.20 RJW68341.1 - 1.4e-05 25.0 0.8 5 7.6 0.2 6.5 6 1 1 7 7 5 1 PPR repeat Clathrin PF00637.20 RJW68341.1 - 3.1e-05 23.9 1.3 2.6 7.9 0.0 5.0 3 1 1 4 4 4 1 Region in Clathrin and VPS PALB2_WD40 PF16756.5 RJW68341.1 - 0.0002 20.4 0.6 0.00042 19.3 0.6 1.5 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 RJW68341.1 - 0.0002 20.5 4.6 0.069 12.2 0.0 3.9 2 1 2 4 4 4 1 Coatomer WD associated region TPR_19 PF14559.6 RJW68341.1 - 0.00034 21.0 15.5 1.3 9.6 1.4 7.0 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW68341.1 - 0.02 14.9 18.2 28 5.1 0.0 8.3 7 1 1 8 8 8 0 Tetratricopeptide repeat PPR_2 PF13041.6 RJW68341.1 - 0.034 14.3 4.2 0.3 11.3 0.2 4.1 4 0 0 4 4 4 0 PPR repeat family ANAPC3 PF12895.7 RJW68341.1 - 0.038 14.2 11.6 1.1 9.5 0.3 6.1 5 2 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RJW68341.1 - 0.073 13.4 26.1 1.8 8.9 3.3 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 RJW68341.1 - 0.074 12.8 4.4 0.46 10.2 0.1 3.9 4 0 0 4 4 4 0 26S proteasome subunit RPN7 TPR_8 PF13181.6 RJW68341.1 - 0.12 12.7 14.1 15 6.1 0.6 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW68341.1 - 0.23 11.3 8.8 48 4.0 0.1 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 RJW68341.1 - 0.3 11.8 23.0 3.6 8.5 1.2 7.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 RJW68341.1 - 0.55 9.9 6.0 23 4.6 0.0 4.4 4 1 0 5 5 5 0 Tetratricopeptide repeat-like domain MIT PF04212.18 RJW68341.1 - 0.74 9.9 11.6 4.4 7.4 0.1 5.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain WD40 PF00400.32 RJW68341.1 - 2.2 9.3 4.4 75 4.4 0.9 4.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Ig_3 PF13927.6 RJW68342.1 - 3.6e-27 94.8 0.0 1.3e-09 38.5 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RJW68342.1 - 4.6e-26 90.7 0.0 8e-09 35.5 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 RJW68342.1 - 4.7e-17 61.9 0.1 0.00024 21.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RJW68342.1 - 4.8e-17 62.1 0.0 4.2e-05 23.8 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RJW68342.1 - 7.6e-11 42.2 1.8 0.00071 19.7 0.0 5.4 3 3 0 3 3 3 2 Immunoglobulin V-set domain C1-set PF07654.15 RJW68342.1 - 4.9e-07 30.0 0.0 0.22 11.9 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin C1-set domain C2-set_2 PF08205.12 RJW68342.1 - 0.00021 21.3 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RJW68342.1 - 0.01 15.4 0.0 0.1 12.2 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain PCI PF01399.27 RJW68343.1 - 8e-13 48.8 0.2 2.8e-12 47.1 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_10 PF13374.6 RJW68343.1 - 0.022 14.6 0.2 11 6.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Guanylate_kin PF00625.21 RJW68345.1 - 1.7e-29 102.8 0.0 9.5e-27 93.8 0.0 2.2 2 0 0 2 2 2 2 Guanylate kinase PDZ PF00595.24 RJW68345.1 - 2.8e-12 46.8 1.4 5e-12 46.0 1.4 1.4 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 RJW68345.1 - 3.3e-06 26.7 0.0 8.6e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 RJW68345.1 - 3.1e-05 23.7 0.1 7.9e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW68345.1 - 0.00065 20.0 0.2 0.0015 18.8 0.2 1.5 1 0 0 1 1 1 1 PDZ domain MMR_HSR1 PF01926.23 RJW68345.1 - 0.00073 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase L27 PF02828.16 RJW68345.1 - 0.0015 18.3 0.1 0.006 16.3 0.0 2.0 1 1 1 2 2 2 1 L27 domain AAA_22 PF13401.6 RJW68345.1 - 0.0019 18.5 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RJW68345.1 - 0.0028 17.7 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SH3_1 PF00018.28 RJW68345.1 - 0.003 17.1 0.3 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 SH3 domain AAA_28 PF13521.6 RJW68345.1 - 0.009 16.3 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RJW68345.1 - 0.012 16.1 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 RJW68345.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RJW68345.1 - 0.017 15.5 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 RJW68345.1 - 0.022 15.0 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 RJW68345.1 - 0.043 14.2 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 RJW68345.1 - 0.045 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 RJW68345.1 - 0.049 14.2 0.0 0.089 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RJW68345.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 RJW68345.1 - 0.079 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 RJW68345.1 - 0.082 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RJW68345.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 NTPase COX15-CtaA PF02628.15 RJW68346.1 - 4.9e-69 232.9 8.2 1e-68 231.8 8.2 1.5 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein RVT_1 PF00078.27 RJW68346.1 - 1.8e-46 158.4 0.0 2.9e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C5-epim_C PF06662.13 RJW68346.1 - 1.1 8.7 2.9 2.8 7.4 0.1 2.6 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus SecE PF00584.20 RJW68346.1 - 4.6 7.2 4.7 0.85 9.6 0.5 2.0 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex CUB PF00431.20 RJW68347.1 - 1e-22 80.5 0.0 2.1e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 CUB domain TIM21 PF08294.11 RJW68348.1 - 7.2e-35 120.0 0.1 8.9e-35 119.7 0.1 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 RJW68348.1 - 8e-06 25.6 0.0 2.4e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 CDI PF02234.19 RJW68349.1 - 0.014 15.5 0.1 0.031 14.5 0.1 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor DUSP PF06337.12 RJW68349.1 - 0.063 13.9 0.0 3.8 8.2 0.0 2.2 2 0 0 2 2 2 0 DUSP domain DUF1759 PF03564.15 RJW68351.1 - 3.1e-10 40.2 0.0 6.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Asp_protease_2 PF13650.6 RJW68351.1 - 9.1e-06 26.2 0.0 2.6e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW68351.1 - 0.012 16.1 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Transferrin PF00405.17 RJW68351.1 - 0.039 13.1 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Transferrin RVP PF00077.20 RJW68351.1 - 0.049 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease MFS_1 PF07690.16 RJW68352.1 - 7.8e-17 61.2 38.9 1.5e-16 60.2 38.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Saf_2TM PF18303.1 RJW68352.1 - 0.17 11.5 0.5 10 5.7 0.4 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain zf-C3HC4_3 PF13920.6 RJW68353.1 - 4.7e-22 77.6 45.1 2.5e-11 43.2 7.4 4.5 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 RJW68353.1 - 1.7e-11 44.0 7.8 7.5e-06 26.2 1.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 RJW68353.1 - 2.7e-10 40.7 0.1 2.2e-05 24.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW68353.1 - 3.1e-08 33.3 1.9 0.0099 16.3 0.1 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RJW68353.1 - 8.2e-08 32.4 0.1 0.014 15.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW68353.1 - 5.7e-07 30.0 0.0 0.004 17.7 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Prok-RING_4 PF14447.6 RJW68353.1 - 7.1e-07 29.0 48.1 7.6e-05 22.5 7.1 5.5 5 1 1 6 6 6 3 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RJW68353.1 - 5.2e-05 23.0 9.3 5.2e-05 23.0 9.3 4.7 3 1 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW68353.1 - 0.0016 18.7 47.7 0.017 15.5 10.1 4.8 4 0 0 4 4 4 3 Ring finger domain zf-RING_5 PF14634.6 RJW68353.1 - 0.0026 17.7 44.3 0.091 12.7 4.6 5.5 4 1 1 5 5 5 3 zinc-RING finger domain LRR_8 PF13855.6 RJW68354.1 - 2.5e-07 30.4 4.4 0.0039 16.9 0.1 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RJW68354.1 - 5.3e-05 23.5 3.2 0.27 11.7 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) EphA2_TM PF14575.6 RJW68354.1 - 0.0004 21.2 0.1 0.00075 20.3 0.1 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 RJW68354.1 - 0.0082 15.7 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Baculovirus 11 kDa family ECSCR PF15820.5 RJW68354.1 - 0.0084 15.9 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator Orf78 PF06024.12 RJW68354.1 - 0.016 15.5 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 RJW68354.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 RJW68354.1 - 0.031 14.2 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Rifin Shisa PF13908.6 RJW68354.1 - 0.037 14.3 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4330 PF14221.6 RJW68354.1 - 0.049 13.8 0.1 0.24 11.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Protocadherin PF08374.11 RJW68354.1 - 0.056 13.4 0.1 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 Protocadherin DUF1180 PF06679.12 RJW68354.1 - 0.1 13.0 1.4 0.15 12.5 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DAG1 PF05454.11 RJW68354.1 - 0.13 11.6 0.6 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2615 PF11027.8 RJW68354.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Equine_IAV_S2 PF06502.11 RJW68354.1 - 2.6 8.2 4.0 1.2 9.3 0.8 2.1 2 1 0 2 2 1 0 Equine infectious anaemia virus S2 protein PDZ PF00595.24 RJW68355.1 - 1.1e-20 73.8 0.8 1.7e-20 73.1 0.8 1.3 1 0 0 1 1 1 1 PDZ domain PH_17 PF18012.1 RJW68355.1 - 7.5e-18 64.0 0.0 1.4e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 PH domain PH PF00169.29 RJW68355.1 - 2.9e-09 37.4 0.0 0.00094 19.7 0.0 2.3 2 0 0 2 2 2 2 PH domain PDZ_6 PF17820.1 RJW68355.1 - 4e-07 29.8 0.1 8.7e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW68355.1 - 1.5e-05 25.3 0.1 2.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.6 RJW68355.1 - 0.1 12.9 0.0 16 5.9 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain PDEase_I PF00233.19 RJW68356.1 - 3.2e-53 180.9 0.2 5.9e-53 180.0 0.2 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RJW68356.1 - 2.4e-21 76.7 0.0 5.1e-11 43.3 0.0 3.3 2 2 0 2 2 2 2 GAF domain GAF_3 PF13492.6 RJW68356.1 - 0.00018 21.8 0.1 3.5 8.0 0.0 4.4 2 2 0 2 2 2 2 GAF domain DDE_Tnp_IS1595 PF12762.7 RJW68357.1 - 1.5e-08 34.8 0.0 3.8e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain DOMON PF03351.17 RJW68358.1 - 2e-09 37.7 0.0 8.8e-08 32.4 0.0 2.2 1 1 1 2 2 2 1 DOMON domain Cytochrom_B561 PF03188.16 RJW68358.1 - 6.4e-08 32.8 5.8 6.4e-08 32.8 5.8 2.0 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 TT_ORF2a PF08197.11 RJW68358.1 - 0.11 12.6 0.6 0.72 9.9 0.1 2.4 2 0 0 2 2 2 0 pORF2a truncated protein Pkinase_Tyr PF07714.17 RJW68359.1 - 4.1e-70 236.0 0.0 6.2e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW68359.1 - 5.9e-21 75.0 0.0 1e-10 41.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Fz PF01392.22 RJW68359.1 - 0.0037 17.9 0.1 0.02 15.5 0.1 2.3 1 0 0 1 1 1 1 Fz domain MazG_C PF18722.1 RJW68359.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 MazG C-terminal domain Aminotran_5 PF00266.19 RJW68360.1 - 5.5e-93 311.9 0.0 6.8e-93 311.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 RJW68360.1 - 5.4e-09 35.7 0.2 7.6e-09 35.3 0.2 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 RJW68360.1 - 1.2e-06 28.1 0.1 1.9e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 RJW68360.1 - 0.0024 16.5 0.1 0.0038 15.8 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 RJW68360.1 - 0.0078 15.0 0.0 0.015 14.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Proteasome PF00227.26 RJW68362.1 - 2.4e-56 190.2 0.2 3.3e-56 189.8 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit RRM_1 PF00076.22 RJW68364.1 - 2.3e-11 43.3 0.0 3.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 RJW68364.1 - 0.03 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 RJW68364.1 - 0.072 13.2 0.5 0.32 11.1 0.5 2.1 1 1 0 1 1 1 0 RNA recognition motif Glyco_transf_7N PF13733.6 RJW68365.1 - 2.3e-36 124.4 0.0 3.9e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RJW68365.1 - 2e-23 81.9 0.0 5.4e-23 80.5 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase CRISPR_assoc PF08798.11 RJW68366.1 - 0.16 12.0 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 CRISPR associated protein DREV PF05219.12 RJW68367.1 - 8.1e-84 280.8 0.0 1e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_11 PF08241.12 RJW68367.1 - 3.9e-09 37.0 0.0 1e-08 35.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RJW68367.1 - 1.1e-08 35.2 0.0 2.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RJW68367.1 - 3.1e-07 31.1 0.0 9.3e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW68367.1 - 8.8e-07 29.5 0.1 3.2e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW68367.1 - 0.018 14.9 0.0 0.43 10.4 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 RJW68367.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase KIND PF16474.5 RJW68368.1 - 0.03 14.2 0.0 0.067 13.1 0.0 1.6 1 1 0 1 1 1 0 Kinase non-catalytic C-lobe domain RPA_C PF08784.11 RJW68369.1 - 2e-14 54.1 0.3 7.2e-14 52.3 0.0 2.0 2 1 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 RJW68369.1 - 0.0019 18.2 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 RJW68369.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 LexA_DNA_bind PF01726.16 RJW68369.1 - 0.027 14.2 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain Peptidase_S9_N PF02897.15 RJW68370.1 - 1.1e-128 429.6 0.0 1.4e-128 429.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 RJW68370.1 - 7.1e-67 225.0 0.0 1.1e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RJW68370.1 - 0.0011 18.3 0.1 0.0026 17.1 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RJW68370.1 - 0.0053 16.4 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 RJW68370.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ribosomal_L13 PF00572.18 RJW68372.1 - 6.1e-11 42.7 0.0 4e-09 36.8 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 RJW68375.1 - 6.3e-28 97.7 0.0 1.1e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ank_2 PF12796.7 RJW68376.1 - 4.9e-25 87.9 4.0 2.9e-11 43.8 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW68376.1 - 5.2e-24 84.0 10.6 2.1e-09 37.5 0.3 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW68376.1 - 1e-23 83.4 7.7 9.6e-10 38.8 0.4 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RJW68376.1 - 1.4e-18 66.5 16.8 1.9e-06 28.1 0.8 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 RJW68376.1 - 9.1e-15 53.3 8.9 0.044 14.3 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ion_trans PF00520.31 RJW68377.1 - 4.5e-44 150.5 6.6 6.4e-44 150.0 6.6 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RJW68377.1 - 1.3e-23 83.2 0.1 8e-23 80.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 RJW68377.1 - 6.8e-13 48.4 4.5 6.8e-13 48.4 4.5 2.4 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 RJW68377.1 - 0.00084 18.1 3.1 0.00084 18.1 3.1 2.5 2 1 1 3 3 3 1 Polycystin cation channel MARVEL PF01284.23 RJW68378.1 - 0.00092 19.3 24.5 0.005 16.9 24.5 1.9 1 1 0 1 1 1 1 Membrane-associating domain Glyco_trans_2_3 PF13632.6 RJW68378.1 - 0.0025 17.8 0.9 0.0025 17.8 0.9 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Herpes_US9 PF06072.11 RJW68380.1 - 0.066 13.1 3.1 0.33 10.8 0.9 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 PIH1 PF08190.12 RJW68382.1 - 1.4e-32 112.5 0.1 1.9e-32 112.0 0.1 1.1 1 0 0 1 1 1 1 PIH1 N-terminal domain Sugar_tr PF00083.24 RJW68383.1 - 5.2e-20 71.7 21.9 1.6e-19 70.1 21.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW68383.1 - 3.1e-15 56.0 24.6 3.1e-15 56.0 24.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TMEMspv1-c74-12 PF11044.8 RJW68383.1 - 0.21 11.6 1.7 0.66 10.0 1.7 1.8 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein RVT_1 PF00078.27 RJW68385.1 - 0.00048 19.7 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Suf PF05843.14 RJW68386.1 - 7.6e-74 249.3 0.0 4.7e-71 240.2 0.0 3.6 2 2 1 3 3 3 2 Suppressor of forked protein (Suf) TTR-52 PF01060.23 RJW68386.1 - 0.078 13.7 0.1 0.18 12.6 0.1 1.5 1 0 0 1 1 1 0 Transthyretin-like family Cwf_Cwc_15 PF04889.12 RJW68386.1 - 0.11 12.2 1.3 0.2 11.3 1.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Med1 PF10744.9 RJW68387.1 - 1.7e-12 47.2 0.1 4.9e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Caudo_bapla_RBP PF08931.10 RJW68389.1 - 0.069 12.6 2.0 0.088 12.3 0.9 1.6 1 1 1 2 2 2 0 Receptor-binding protein of phage tail base-plate Siphoviridae, head Macoilin PF09726.9 RJW68389.1 - 5.5 5.4 12.4 7 5.1 12.4 1.1 1 0 0 1 1 1 0 Macoilin family Glycolytic PF00274.19 RJW68391.1 - 3.9e-165 548.8 0.0 5.8e-165 548.2 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I SCFA_trans PF02667.14 RJW68392.1 - 0.11 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Short chain fatty acid transporter DDHD PF02862.17 RJW68394.1 - 2.6e-12 47.4 0.1 5.3e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 DDHD domain WWE PF02825.20 RJW68394.1 - 0.006 17.2 0.2 0.024 15.2 0.1 2.2 2 1 0 2 2 2 1 WWE domain zf-met PF12874.7 RJW68395.1 - 0.00017 21.8 2.8 0.00041 20.6 2.8 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RJW68395.1 - 0.00059 20.1 1.5 0.0011 19.2 1.5 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RJW68395.1 - 0.0015 18.8 0.7 0.0033 17.7 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DinI PF06183.13 RJW68395.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 DinI-like family zf_C2H2_ZHX PF18387.1 RJW68395.1 - 0.23 11.1 2.7 0.3 10.7 0.4 2.2 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 RJW68395.1 - 5.5 7.6 6.8 1.9 9.0 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain C2-set_2 PF08205.12 RJW68396.1 - 6.9e-07 29.3 0.5 4.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 RJW68396.1 - 9.9e-05 22.9 0.3 0.33 11.6 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RJW68396.1 - 0.0087 16.2 0.5 0.021 15.0 0.1 1.8 2 1 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 RJW68396.1 - 0.03 14.4 0.8 0.39 10.8 0.2 2.4 2 2 0 2 2 2 0 Immunoglobulin I-set domain ig PF00047.25 RJW68396.1 - 0.33 11.2 6.2 9.1 6.5 3.5 2.6 2 1 0 2 2 2 0 Immunoglobulin domain Clat_adaptor_s PF01217.20 RJW68397.1 - 2e-56 189.9 1.1 2.4e-56 189.6 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ParA PF10609.9 RJW68399.1 - 7.4e-90 300.7 0.0 8.9e-90 300.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RJW68399.1 - 1.3e-08 35.0 0.0 6.1e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 RJW68399.1 - 4.2e-06 26.2 1.8 0.00014 21.1 0.9 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 RJW68399.1 - 1.1e-05 24.9 0.3 5e-05 22.7 0.1 2.2 2 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 RJW68399.1 - 1.1e-05 25.5 0.2 5.3e-05 23.2 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.6 RJW68399.1 - 0.0013 18.6 0.2 0.76 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 RJW68399.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 RJW68399.1 - 0.015 14.9 0.4 0.027 14.1 0.4 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 RJW68399.1 - 0.017 14.3 0.8 0.028 13.6 0.8 1.3 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 RJW68399.1 - 0.017 14.1 0.5 0.025 13.5 0.5 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 RJW68399.1 - 0.052 13.3 0.1 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 RJW68399.1 - 0.1 13.1 0.1 0.17 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RJW68399.1 - 0.11 12.9 1.4 0.14 12.6 0.3 1.7 2 0 0 2 2 2 0 AAA ATPase domain Fer4_NifH PF00142.18 RJW68399.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Zeta_toxin PF06414.12 RJW68399.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF4911 PF16256.5 RJW68399.1 - 0.19 11.7 0.1 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) RsgA_GTPase PF03193.16 RJW68399.1 - 0.21 11.5 0.7 0.52 10.2 0.7 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 RJW68399.1 - 0.3 11.0 1.7 0.34 10.8 0.6 1.6 2 0 0 2 2 1 0 NACHT domain RRM_1 PF00076.22 RJW68400.1 - 2e-33 114.1 0.1 5.3e-19 67.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW68400.1 - 1e-07 32.0 0.1 0.045 13.9 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 RJW68400.1 - 0.013 15.3 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_5 PF13893.6 RJW68400.1 - 0.07 12.7 0.0 8.9 5.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.7 RJW68401.1 - 4.2e-15 55.6 14.2 5.9e-06 26.5 0.5 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW68401.1 - 3.4e-10 39.9 11.9 0.00021 21.5 1.4 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RJW68401.1 - 0.00011 22.5 12.2 0.0039 17.5 0.2 3.7 3 1 1 4 4 4 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 RJW68401.1 - 0.0013 19.0 5.7 1.8 8.8 0.1 3.2 3 0 0 3 3 3 3 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 RJW68401.1 - 0.024 15.1 14.0 1.1 9.8 0.3 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW68401.1 - 0.56 11.2 9.1 2 9.5 0.8 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-DBF PF07535.12 RJW68401.1 - 1.4 9.0 6.5 33 4.7 0.0 3.5 3 0 0 3 3 3 0 DBF zinc finger DUF3449 PF11931.8 RJW68401.1 - 3 7.6 10.0 5.4 6.8 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3449) zf-U1 PF06220.12 RJW68401.1 - 5.9 6.8 11.9 0.62 9.9 0.8 3.6 4 0 0 4 4 4 0 U1 zinc finger EB PF01683.18 RJW68402.1 - 4.5e-09 36.5 350.7 0.054 13.8 9.6 24.6 12 8 12 24 24 24 17 EB module NIDO PF06119.14 RJW68402.1 - 2.8e-07 31.4 0.0 1.1e-06 29.5 0.0 2.0 2 0 0 2 2 2 1 Nidogen-like EGF_3 PF12947.7 RJW68402.1 - 0.00065 19.8 8.4 0.00065 19.8 8.4 26.1 25 0 0 25 25 25 14 EGF domain Ig_3 PF13927.6 RJW68402.1 - 0.0025 18.4 0.0 0.01 16.4 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain hEGF PF12661.7 RJW68402.1 - 0.64 10.7 267.0 0.11 13.2 3.6 24.8 24 0 0 24 24 24 0 Human growth factor-like EGF Cadherin PF00028.17 RJW68403.1 - 4.4e-60 200.1 5.6 1.3e-21 76.9 0.3 6.7 6 0 0 6 6 6 6 Cadherin domain Cadherin_3 PF16184.5 RJW68403.1 - 1.3e-07 31.6 4.4 0.09 12.8 0.0 5.0 6 0 0 6 6 6 3 Cadherin-like SID-1_RNA_chan PF13965.6 RJW68403.1 - 0.061 11.7 0.3 0.11 10.9 0.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3439 PF11921.8 RJW68404.1 - 0.004 17.1 11.5 0.013 15.5 11.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) DUF4698 PF15769.5 RJW68404.1 - 0.02 14.0 4.1 0.032 13.3 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Mucin PF01456.17 RJW68404.1 - 0.29 11.1 19.6 0.92 9.5 19.6 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 RJW68404.1 - 8.6 4.2 7.0 12 3.8 7.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ECH_1 PF00378.20 RJW68406.1 - 3.3e-28 98.7 0.3 3.9e-28 98.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RJW68406.1 - 1.7e-14 54.1 0.0 5.5e-12 45.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase RVT_1 PF00078.27 RJW68407.1 - 1.3e-46 158.9 0.6 7.3e-46 156.4 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AKAP7_NLS PF10469.9 RJW68407.1 - 8.5e-33 114.0 0.0 1.3e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain MJ1316 PF04457.12 RJW68407.1 - 6.3e-23 81.3 0.1 1.6e-22 80.0 0.1 1.8 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos_2 PF14529.6 RJW68407.1 - 7.8e-12 45.1 0.0 5.7e-11 42.3 0.0 2.5 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase 2_5_RNA_ligase2 PF13563.6 RJW68407.1 - 7.1e-06 26.0 0.0 3.2e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 RJW68407.1 - 1.3e-05 25.3 0.0 0.056 13.6 0.0 2.9 2 0 0 2 2 2 2 LigT like Phosphoesterase Sema PF01403.19 RJW68408.1 - 1.6e-48 165.6 0.1 2.6e-48 164.9 0.1 1.3 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.19 RJW68408.1 - 6.1e-06 26.4 89.6 0.0011 19.2 9.0 10.1 8 2 0 8 8 8 5 Thrombospondin type 1 domain cobW PF02492.19 RJW68408.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF1087 PF06465.13 RJW68408.1 - 0.16 12.0 3.5 0.43 10.6 3.5 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) RRM_1 PF00076.22 RJW68409.1 - 1.6e-08 34.2 0.1 2.5e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.6 RJW68410.1 - 1.8e-15 56.3 60.2 0.0033 18.1 0.5 9.4 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW68410.1 - 6.1e-13 48.5 67.0 0.00013 22.2 0.6 9.4 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW68410.1 - 8.1e-11 41.8 5.3 5.4e-09 36.1 0.2 7.9 8 0 0 8 8 8 3 Zinc-finger double domain zf-met PF12874.7 RJW68410.1 - 6.4e-07 29.5 38.0 0.00075 19.8 0.7 8.8 9 0 0 9 9 9 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RJW68410.1 - 0.00056 19.6 37.6 0.036 13.8 0.3 7.9 8 0 0 8 8 8 3 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RJW68410.1 - 0.0047 17.2 3.0 0.098 13.0 0.1 5.7 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf_PR_Knuckle PF18445.1 RJW68410.1 - 0.023 14.5 0.4 0.023 14.5 0.4 3.2 3 0 0 3 3 3 0 PR zinc knuckle motif zf-C2H2_6 PF13912.6 RJW68410.1 - 0.072 13.1 0.3 0.072 13.1 0.3 7.1 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 RJW68410.1 - 0.23 12.1 25.8 0.17 12.6 9.6 4.7 1 1 5 6 6 6 0 Zinc finger C2H2-type, 3 repeats F-box_5 PF18511.1 RJW68410.1 - 0.92 9.1 3.2 1.9 8.1 3.2 1.5 1 0 0 1 1 1 0 F-box Mut7-C PF01927.16 RJW68410.1 - 1.3 9.1 13.1 5.5 7.1 1.0 3.6 2 1 1 3 3 3 0 Mut7-C RNAse domain U71 PF17474.2 RJW68410.1 - 3.4 7.7 9.7 16 5.6 0.0 3.8 4 0 0 4 4 4 0 Tegument protein UL11 homolog zf-C2H2_2 PF12756.7 RJW68410.1 - 4.1 7.8 39.1 0.56 10.6 0.8 6.9 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) ToxB_N PF18224.1 RJW68411.1 - 0.0012 18.7 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 2 ToxB N-terminal domain HA PF03457.14 RJW68411.1 - 0.008 16.5 0.0 6.3 7.2 0.0 2.3 2 0 0 2 2 2 2 Helicase associated domain Me-amine-dh_L PF02975.14 RJW68411.1 - 0.0084 16.6 0.0 7.3 7.1 0.0 2.4 2 0 0 2 2 2 2 Methylamine dehydrogenase, L chain DUF3018 PF11455.8 RJW68411.1 - 0.046 13.7 0.4 14 5.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) DUF5047 PF16466.5 RJW68411.1 - 0.12 12.8 0.0 23 5.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5047) DUF2694 PF10904.8 RJW68411.1 - 0.18 11.9 0.0 34 4.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2694) RVT_1 PF00078.27 RJW68412.1 - 1.1e-44 152.6 0.0 1.9e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_E_B PF04042.16 RJW68412.1 - 3.7e-17 62.4 1.0 6.7e-17 61.6 0.3 1.8 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Exo_endo_phos_2 PF14529.6 RJW68412.1 - 7e-07 29.1 0.0 1.9e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW68412.1 - 0.0088 15.6 0.7 0.025 14.1 0.2 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family V-set PF07686.17 RJW68415.1 - 3.3e-23 81.9 15.4 0.0031 17.7 0.0 9.8 9 0 0 9 9 9 8 Immunoglobulin V-set domain I-set PF07679.16 RJW68415.1 - 1e-12 47.9 3.2 4.8 7.3 0.0 9.5 9 0 0 9 9 9 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW68415.1 - 2.3e-12 47.3 12.9 13 6.5 0.1 10.4 9 0 0 9 9 9 6 Immunoglobulin domain Izumo-Ig PF16706.5 RJW68415.1 - 3.2e-10 39.9 1.8 0.16 12.0 0.0 7.8 8 0 0 8 8 8 2 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 RJW68415.1 - 5e-10 39.6 17.4 2.3 8.6 0.0 10.1 10 0 0 10 10 10 3 Immunoglobulin domain ig PF00047.25 RJW68415.1 - 1.6e-08 34.6 14.4 0.13 12.5 0.0 9.1 9 0 0 9 9 9 3 Immunoglobulin domain Ig_6 PF18452.1 RJW68415.1 - 0.025 14.2 18.0 16 5.2 0.0 8.4 9 0 0 9 9 9 0 Immunoglobulin domain zf-LITAF-like PF10601.9 RJW68416.1 - 3.4e-10 40.0 1.1 5.5e-10 39.4 1.1 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DUF4817 PF16087.5 RJW68417.1 - 5e-11 42.2 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) BACK PF07707.15 RJW68419.1 - 1.5e-10 41.1 1.1 1.4e-05 25.1 0.2 2.3 2 0 0 2 2 2 2 BTB And C-terminal Kelch HpaB_N PF11794.8 RJW68419.1 - 1.2e-05 25.2 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 2 4-hydroxyphenylacetate 3-hydroxylase N terminal Glyco_hydro_67N PF03648.14 RJW68419.1 - 0.00094 19.5 0.3 1 9.7 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 67 N-terminus BMP2K_C PF15282.6 RJW68419.1 - 0.024 14.5 1.0 4 7.2 0.1 2.2 2 0 0 2 2 2 0 BMP-2-inducible protein kinase C-terminus Methyltransf_PK PF05891.12 RJW68419.1 - 0.035 13.6 0.0 7.3 6.0 0.0 2.1 1 1 1 2 2 2 0 AdoMet dependent proline di-methyltransferase Npun_R1517 PF18068.1 RJW68419.1 - 0.12 12.7 0.2 25 5.3 0.0 2.3 2 0 0 2 2 2 0 Npun R1517 TRA-1_regulated PF02343.16 RJW68419.1 - 0.14 12.2 3.0 8.7 6.4 0.2 2.1 2 0 0 2 2 2 0 TRA-1 regulated protein R03H10.4 Neocarzinostat PF00960.18 RJW68419.1 - 0.24 11.4 6.2 4.3 7.4 0.6 2.5 2 2 0 2 2 2 0 Neocarzinostatin family Dynein_IC2 PF11540.8 RJW68419.1 - 1.6 8.8 5.6 21 5.2 0.5 2.6 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 V-SNARE_C PF12352.8 RJW68421.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus PDEase_I PF00233.19 RJW68423.1 - 3.4e-35 121.9 4.7 4.7e-35 121.4 4.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Na_K-ATPase PF00287.18 RJW68425.1 - 6.1e-18 65.0 0.0 6.8e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain T-box PF00907.22 RJW68426.1 - 4e-85 284.7 0.0 1e-77 260.6 0.0 2.4 2 0 0 2 2 2 2 T-box IL17R_fnIII_D1 PF16556.5 RJW68426.1 - 0.06 13.0 0.4 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Interleukin-17 receptor, fibronectin-III-like domain 1 WAC_Acf1_DNA_bd PF10537.9 RJW68427.1 - 1.3e-19 70.6 0.0 2.8e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 RJW68427.1 - 2.9e-12 46.7 0.0 8.7e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 RJW68427.1 - 1.2e-09 38.5 0.0 7.2e-08 32.8 0.0 3.5 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 RJW68427.1 - 1.9e-08 33.6 0.6 8e-08 31.6 0.6 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Exo_endo_phos_2 PF14529.6 RJW68427.1 - 1.5e-06 28.1 0.0 4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Rossmann-like PF10727.9 RJW68427.1 - 0.013 15.4 0.4 0.036 13.9 0.1 1.9 2 0 0 2 2 2 0 Rossmann-like domain E1_DerP2_DerF2 PF02221.15 RJW68428.1 - 0.0012 19.3 0.0 0.002 18.6 0.0 1.4 1 1 0 1 1 1 1 ML domain zf-C2H2 PF00096.26 RJW68430.1 - 0.024 15.1 4.7 0.068 13.7 4.7 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type CxxCxxCC PF03692.15 RJW68430.1 - 0.056 14.1 1.9 0.13 13.0 1.9 1.7 1 0 0 1 1 1 0 Putative zinc- or iron-chelating domain YukC PF10140.9 RJW68432.1 - 0.014 14.2 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC E1_DerP2_DerF2 PF02221.15 RJW68433.1 - 3.9e-14 53.2 0.0 4.3e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 ML domain SAM_4 PF18017.1 RJW68433.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase PF00069.25 RJW68435.1 - 6.5e-59 199.5 0.0 2.4e-20 73.0 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68435.1 - 1.7e-30 106.2 0.0 1.2e-12 47.7 0.0 4.5 4 0 0 4 4 4 4 Protein tyrosine kinase RWD PF05773.22 RJW68435.1 - 3.8e-07 30.4 0.0 9.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.6 RJW68435.1 - 5.2e-05 22.7 0.0 0.0095 15.3 0.0 2.6 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 RJW68435.1 - 0.00019 21.5 1.0 0.00049 20.1 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW68435.1 - 0.0014 17.7 0.3 1.5 7.6 0.0 2.6 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 RJW68435.1 - 0.052 12.9 0.3 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RJW68435.1 - 0.082 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 CAP PF00188.26 RJW68438.1 - 2.7e-19 70.2 0.3 3.3e-19 69.9 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 RJW68439.1 - 1.9e-18 67.5 0.0 2.5e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SAPS PF04499.15 RJW68440.1 - 0.069 11.9 3.5 0.093 11.5 3.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAN_3 PF08277.12 RJW68440.1 - 2.9 7.7 10.4 1.2 9.0 3.6 2.9 2 0 0 2 2 2 0 PAN-like domain SRP-alpha_N PF04086.13 RJW68440.1 - 3.9 7.3 14.4 7.3 6.4 14.4 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal dDENN PF03455.19 RJW68441.1 - 0.0037 17.2 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 dDENN domain GCK PF07802.11 RJW68441.1 - 0.007 16.8 1.2 0.013 15.9 1.2 1.4 1 0 0 1 1 1 1 GCK domain Cmc1 PF08583.10 RJW68441.1 - 0.052 13.6 1.6 0.11 12.6 1.6 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 RJW68441.1 - 0.17 12.2 3.0 0.39 11.0 0.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Asp PF00026.23 RJW68443.1 - 7.9e-44 150.3 0.0 9.2e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW68443.1 - 3.9e-08 33.7 0.0 0.0053 17.0 0.0 3.0 2 1 0 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RJW68443.1 - 1.4e-05 25.6 0.0 0.13 12.9 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 RJW68443.1 - 0.0029 18.1 0.0 0.012 16.1 0.0 2.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 RJW68443.1 - 0.17 12.2 0.0 4.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease E1_DerP2_DerF2 PF02221.15 RJW68444.1 - 1.8e-09 38.1 0.1 1.9e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 ML domain MULE PF10551.9 RJW68445.1 - 0.12 12.9 0.0 0.48 10.9 0.0 2.0 3 0 0 3 3 3 0 MULE transposase domain CAP PF00188.26 RJW68450.1 - 3.7e-18 66.6 0.2 5.3e-18 66.1 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rhodanese PF00581.20 RJW68451.1 - 3.6e-14 53.2 0.0 8e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Metallophos PF00149.28 RJW68452.1 - 1.3e-30 107.4 0.1 3e-30 106.3 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RJW68452.1 - 4.1e-12 46.3 1.0 1e-11 45.1 1.0 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain CBF PF03914.17 RJW68453.1 - 5.9e-22 78.5 0.5 1.3e-21 77.3 0.3 1.7 2 0 0 2 2 2 1 CBF/Mak21 family CPBP PF02517.16 RJW68453.1 - 2.5e-16 59.8 5.9 6.3e-16 58.5 5.9 1.7 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease Strep_pep PF14404.6 RJW68455.1 - 0.11 12.7 0.0 19 5.6 0.0 3.0 3 0 0 3 3 3 0 Ribosomally synthesized peptide in Streptomyces species Perm-CXXC PF15629.6 RJW68455.1 - 0.14 12.4 4.2 1.2 9.5 0.2 2.6 3 0 0 3 3 3 0 Permuted single zf-CXXC unit Hist_deacetyl PF00850.19 RJW68456.1 - 2e-66 224.6 0.0 8.9e-46 156.8 0.0 2.3 2 0 0 2 2 2 2 Histone deacetylase domain SOCS_box PF07525.16 RJW68459.1 - 0.00034 20.9 3.9 0.00088 19.6 2.8 2.2 2 0 0 2 2 2 1 SOCS box Ank_2 PF12796.7 RJW68459.1 - 0.0067 17.0 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Dpy19 PF10034.9 RJW68462.1 - 4.9e-134 448.0 0.0 3.5e-131 438.6 0.0 3.5 1 1 0 1 1 1 1 Q-cell neuroblast polarisation XPG_N PF00752.17 RJW68463.1 - 7e-25 87.4 0.0 1.5e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RJW68463.1 - 3e-22 78.8 0.0 8.1e-22 77.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 RJW68463.1 - 0.0006 20.4 0.0 0.0018 18.8 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold PAPA-1 PF04795.12 RJW68463.1 - 1.2 10.0 7.9 0.2 12.5 3.5 2.0 2 0 0 2 2 2 0 PAPA-1-like conserved region NUDIX PF00293.28 RJW68466.1 - 1.1e-05 25.4 0.0 7.2e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain DUF5431 PF17496.2 RJW68467.1 - 0.091 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5431) Band_7 PF01145.25 RJW68471.1 - 2.5e-28 99.3 3.6 4.4e-28 98.5 3.6 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 RJW68471.1 - 0.0047 16.7 0.1 0.0082 15.9 0.1 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF4005 PF13178.6 RJW68474.1 - 0.072 13.8 1.9 0.13 13.0 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4005) RVT_1 PF00078.27 RJW68477.1 - 8.5e-41 139.9 0.0 1.9e-40 138.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW68477.1 - 7.1e-07 29.1 0.0 2.1e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TF_Zn_Ribbon PF08271.12 RJW68477.1 - 8.1e-06 25.3 3.1 1.7e-05 24.2 3.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RRN7 PF11781.8 RJW68477.1 - 0.0014 18.2 0.9 0.0028 17.3 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Prim_Zn_Ribbon PF08273.12 RJW68477.1 - 0.049 13.9 2.1 0.1 12.9 2.1 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase DUF2277 PF10041.9 RJW68480.1 - 0.12 12.8 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) Synaptobrevin PF00957.21 RJW68481.1 - 8e-29 99.3 1.8 1e-28 98.9 1.8 1.1 1 0 0 1 1 1 1 Synaptobrevin Fijivirus_P9-2 PF06837.11 RJW68481.1 - 0.0032 17.0 0.0 0.0045 16.5 0.0 1.1 1 0 0 1 1 1 1 Fijivirus P9-2 protein OAD_gamma PF04277.13 RJW68481.1 - 0.032 14.8 0.1 0.074 13.7 0.0 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4337 PF14235.6 RJW68481.1 - 0.094 12.8 0.3 0.14 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3357 PF11837.8 RJW68481.1 - 0.12 12.8 0.4 0.27 11.7 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Baculo_PEP_C PF04513.12 RJW68482.1 - 0.00011 22.2 2.3 0.00028 20.9 2.3 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 RJW68482.1 - 0.0014 18.6 7.7 0.0016 18.3 7.7 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain EzrA PF06160.12 RJW68482.1 - 0.0038 15.5 7.3 0.0048 15.1 7.3 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Syntaxin-6_N PF09177.11 RJW68482.1 - 0.0084 16.6 4.6 0.084 13.4 4.2 2.0 1 1 1 2 2 2 1 Syntaxin 6, N-terminal DUF4164 PF13747.6 RJW68482.1 - 0.014 15.7 3.3 0.028 14.7 1.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) HSCB_C PF07743.13 RJW68482.1 - 0.014 15.8 8.0 0.27 11.7 8.0 2.2 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Nbl1_Borealin_N PF10444.9 RJW68482.1 - 0.017 14.7 2.4 0.33 10.6 0.2 2.3 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal FeS_assembly_P PF01883.19 RJW68482.1 - 0.028 14.6 0.2 0.58 10.4 0.0 2.4 2 1 1 3 3 3 0 Iron-sulfur cluster assembly protein Tweety PF04906.13 RJW68482.1 - 0.064 11.9 1.8 0.07 11.8 1.8 1.1 1 0 0 1 1 1 0 Tweety DUF4238 PF14022.6 RJW68482.1 - 0.065 12.7 2.3 0.091 12.3 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4238) DUF883 PF05957.13 RJW68482.1 - 0.077 13.6 3.5 0.31 11.7 3.5 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Prefoldin_2 PF01920.20 RJW68482.1 - 0.077 13.0 12.5 0.096 12.6 9.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 RJW68482.1 - 0.08 13.1 4.3 0.11 12.7 4.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Focal_AT PF03623.13 RJW68482.1 - 0.094 12.7 3.1 0.23 11.4 3.1 1.6 1 1 0 1 1 1 0 Focal adhesion targeting region REC1 PF18501.1 RJW68482.1 - 0.097 12.5 6.3 0.1 12.5 6.3 1.0 1 0 0 1 1 1 0 Alpha helical recognition lobe domain PIN_8 PF18476.1 RJW68482.1 - 0.11 12.4 3.9 0.13 12.1 3.9 1.1 1 0 0 1 1 1 0 PIN like domain OmpH PF03938.14 RJW68482.1 - 0.15 12.4 13.3 0.26 11.6 13.3 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Lectin_N PF03954.14 RJW68482.1 - 0.22 11.3 5.5 0.32 10.7 5.5 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain FlaC_arch PF05377.11 RJW68482.1 - 0.22 11.9 6.7 29 5.2 5.2 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1451 PF07295.11 RJW68482.1 - 0.24 11.4 3.8 0.29 11.2 3.8 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain ZapA PF05164.13 RJW68482.1 - 0.29 11.6 7.1 1.6 9.2 1.6 2.2 1 1 1 2 2 2 0 Cell division protein ZapA Cullin_Nedd8 PF10557.9 RJW68482.1 - 0.32 11.1 4.2 0.89 9.6 0.8 2.1 2 0 0 2 2 2 0 Cullin protein neddylation domain DUF1664 PF07889.12 RJW68482.1 - 0.32 11.0 4.9 0.62 10.1 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Sigma70_ner PF04546.13 RJW68482.1 - 0.36 10.7 7.6 0.97 9.3 7.5 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region YojJ PF10372.9 RJW68482.1 - 0.37 10.9 5.3 1 9.5 1.0 2.2 1 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF4407 PF14362.6 RJW68482.1 - 0.38 10.1 5.1 0.43 9.9 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4404 PF14357.6 RJW68482.1 - 0.45 11.2 6.8 1.3 9.7 6.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) FapA PF03961.13 RJW68482.1 - 0.48 9.0 7.8 0.56 8.7 7.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A COG2 PF06148.11 RJW68482.1 - 0.61 10.2 7.0 1.2 9.2 7.0 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 YtxH PF12732.7 RJW68482.1 - 0.66 10.5 6.0 1.1 9.9 6.0 1.5 1 1 0 1 1 1 0 YtxH-like protein SSFA2_C PF14723.6 RJW68482.1 - 0.9 9.4 6.7 0.65 9.9 1.8 2.1 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Nas2_N PF18265.1 RJW68482.1 - 0.97 9.4 5.1 21 5.1 0.0 2.7 2 1 0 2 2 2 0 Nas2 N_terminal domain Enkurin PF13864.6 RJW68482.1 - 1 9.8 9.8 29 5.2 9.8 2.6 1 1 0 1 1 1 0 Calmodulin-binding TMPIT PF07851.13 RJW68482.1 - 1.2 8.3 5.1 1.4 8.1 5.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Borealin PF10512.9 RJW68482.1 - 1.4 8.9 5.7 1.5 8.8 0.9 2.4 1 1 2 3 3 3 0 Cell division cycle-associated protein 8 DUF1690 PF07956.11 RJW68482.1 - 1.6 9.1 9.6 2.3 8.6 9.6 1.3 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF2175 PF09943.9 RJW68482.1 - 1.9 8.9 6.7 2.1 8.7 5.9 1.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) RVT_1 PF00078.27 RJW68483.1 - 1.9e-12 47.2 0.0 1e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_2b PF00587.25 RJW68486.1 - 1.7e-32 112.8 0.0 9e-30 104.0 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RJW68486.1 - 4.1e-20 71.7 0.1 8.8e-20 70.7 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 RJW68486.1 - 4.1e-14 52.4 0.0 8e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 RJW68486.1 - 1.6e-10 40.9 0.0 4.5e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain IRF-2BP1_2 PF11261.8 RJW68490.1 - 2.1e-30 104.0 3.2 1.8e-29 101.1 2.1 2.4 2 0 0 2 2 2 1 Interferon regulatory factor 2-binding protein zinc finger DUF3079 PF11278.8 RJW68490.1 - 0.02 14.7 2.4 2.9 7.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) zf-C3HC4 PF00097.25 RJW68490.1 - 0.075 12.9 1.2 0.26 11.2 1.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tctex-1 PF03645.13 RJW68491.1 - 4e-15 55.9 0.0 5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family CAP PF00188.26 RJW68492.1 - 1.6e-18 67.8 2.2 1.6e-18 67.8 2.2 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family MAP7 PF05672.11 RJW68492.1 - 0.00012 21.8 18.0 0.00024 20.8 18.0 1.4 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Auts2 PF15336.6 RJW68492.1 - 0.0084 16.3 1.9 0.01 16.0 1.9 1.3 1 0 0 1 1 1 1 Autism susceptibility gene 2 protein Borrelia_P83 PF05262.11 RJW68492.1 - 0.14 10.6 9.6 0.18 10.3 9.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 RJW68492.1 - 0.15 11.9 7.8 0.25 11.1 7.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM199X PF15814.5 RJW68492.1 - 0.3 10.1 3.2 0.42 9.6 3.2 1.2 1 0 0 1 1 1 0 Protein family FAM199X GBP_C PF02841.14 RJW68492.1 - 0.54 9.6 15.1 0.94 8.8 15.1 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain NARP1 PF12569.8 RJW68492.1 - 4.9 5.9 15.4 7.6 5.3 15.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SAGA-Tad1 PF12767.7 RJW68492.1 - 5 6.8 11.8 4.2 7.0 8.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Connexin PF00029.19 RJW68492.1 - 5.9 6.6 11.1 7.7 6.2 9.7 1.7 2 0 0 2 2 2 0 Connexin HemY_N PF07219.13 RJW68494.1 - 0.26 11.5 1.0 2.5 8.3 0.2 2.4 2 0 0 2 2 2 0 HemY protein N-terminus EphA2_TM PF14575.6 RJW68494.1 - 0.32 11.9 2.5 0.39 11.6 0.8 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Phenol_Hydrox PF02332.18 RJW68498.1 - 0.0043 16.6 0.1 0.0049 16.4 0.1 1.1 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase Amidase_2 PF01510.25 RJW68500.1 - 4e-10 40.2 0.0 1.2e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase BCAS3 PF12490.8 RJW68500.1 - 0.15 11.5 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Far-17a_AIG1 PF04750.14 RJW68501.1 - 1.8e-15 56.8 19.0 3.1e-15 56.0 18.8 1.4 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein CYSTM PF12734.7 RJW68501.1 - 0.035 14.4 1.3 0.08 13.3 1.3 1.6 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DHHC PF01529.20 RJW68501.1 - 0.042 14.0 0.6 0.042 14.0 0.6 2.9 2 1 0 2 2 2 0 DHHC palmitoyltransferase Sec63 PF02889.16 RJW68503.1 - 2.2e-16 59.8 0.5 1e-09 37.9 0.2 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 RJW68503.1 - 1.7e-13 50.4 0.6 4.4e-13 49.1 0.3 1.9 2 0 0 2 2 2 1 DnaJ domain RVT_1 PF00078.27 RJW68503.1 - 0.0041 16.6 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FERM_M PF00373.18 RJW68504.1 - 4.2e-21 75.5 0.1 1.1e-19 71.0 0.1 2.3 1 1 0 1 1 1 1 FERM central domain Kindlin_2_N PF18124.1 RJW68504.1 - 2e-17 63.1 0.0 5.1e-17 61.8 0.0 1.7 1 1 0 1 1 1 1 Kindlin-2 N-terminal domain FERM_N PF09379.10 RJW68504.1 - 0.0061 16.5 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 FERM N-terminal domain LRR_8 PF13855.6 RJW68505.1 - 1.5e-22 79.1 16.8 2.5e-09 36.8 5.9 4.6 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 RJW68505.1 - 5.4e-15 55.3 17.4 2.1e-05 24.8 0.1 5.2 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW68505.1 - 2.5e-06 27.2 17.5 2.3 9.1 0.1 7.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_5 PF13306.6 RJW68505.1 - 1.2e-05 25.2 0.0 0.00058 19.8 0.0 2.6 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RJW68505.1 - 0.023 14.2 1.0 3.6 7.1 0.2 2.8 1 1 2 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 RJW68505.1 - 9.5 6.6 15.8 5.1 7.4 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat RT_RNaseH PF17917.1 RJW68506.1 - 4.4e-13 49.4 0.1 1.2e-10 41.7 0.0 2.3 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW68506.1 - 5.6e-10 39.1 0.7 6.4e-06 26.1 0.0 2.9 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase Mid2 PF04478.12 RJW68506.1 - 0.072 12.9 0.0 0.096 12.5 0.0 1.3 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Mob1_phocein PF03637.17 RJW68508.1 - 3.6e-76 254.9 0.2 4.3e-76 254.6 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family THDPS_N_2 PF14805.6 RJW68508.1 - 0.045 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal SDF PF00375.18 RJW68509.1 - 3.1e-113 378.7 23.8 3.5e-113 378.5 23.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MAM PF00629.23 RJW68512.1 - 0.00093 19.2 1.3 1.3 9.0 0.0 2.5 3 0 0 3 3 3 2 MAM domain, meprin/A5/mu DUF4543 PF15076.6 RJW68512.1 - 0.017 15.2 0.3 0.037 14.2 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4543) ATG2_CAD PF13329.6 RJW68514.1 - 0.00076 19.2 0.1 0.0023 17.6 0.1 1.7 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif P5CR_dimer PF14748.6 RJW68515.1 - 3.6e-37 126.8 0.8 3.6e-37 126.8 0.8 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 RJW68515.1 - 6.5e-16 58.7 0.3 2.5e-15 56.8 0.3 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 RJW68515.1 - 0.063 12.3 0.1 0.088 11.8 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase RhoGAP PF00620.27 RJW68518.1 - 2.6e-41 141.0 0.0 4.4e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain SH2 PF00017.24 RJW68518.1 - 8e-15 54.7 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.22 RJW68518.1 - 3.8e-14 52.3 4.6 6.9e-14 51.5 4.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 RJW68518.1 - 0.086 13.2 3.3 0.19 12.1 3.3 1.5 1 0 0 1 1 1 0 C1 domain zf-RING-like PF08746.11 RJW68518.1 - 0.32 11.3 3.9 0.62 10.4 3.9 1.4 1 0 0 1 1 1 0 RING-like domain Peptidase_M16_M PF16187.5 RJW68519.1 - 3.6e-06 26.5 0.0 5.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_S21 PF00716.17 RJW68519.1 - 0.09 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) CLU_N PF15044.6 RJW68519.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term Spore_YtfJ PF09579.10 RJW68520.1 - 1.5 9.0 7.9 78 3.5 0.2 4.2 3 0 0 3 3 3 0 Sporulation protein YtfJ (Spore_YtfJ) BTB PF00651.31 RJW68521.1 - 3.9e-09 36.7 0.3 4.6e-09 36.5 0.3 1.1 1 0 0 1 1 1 1 BTB/POZ domain A_deaminase PF00962.22 RJW68522.1 - 1.7e-105 353.0 0.1 2.5e-105 352.5 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-C2H2_4 PF13894.6 RJW68523.1 - 5.3e-12 45.5 70.8 0.00052 20.6 0.4 10.8 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW68523.1 - 1e-07 32.0 72.9 0.00049 20.4 1.0 10.8 10 1 0 10 10 9 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW68523.1 - 2.3e-07 30.9 50.7 0.00047 20.5 1.2 10.3 10 0 0 10 10 10 4 Zinc-finger double domain zf-Di19 PF05605.12 RJW68523.1 - 0.00033 20.9 1.1 0.00033 20.9 1.1 6.6 5 1 3 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RJW68523.1 - 0.00072 19.9 20.0 0.35 11.3 0.1 6.0 6 0 0 6 6 5 3 Zinc-finger of C2H2 type zf-DNA_Pol PF08996.10 RJW68523.1 - 0.0066 16.2 2.9 0.039 13.7 1.2 2.7 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger zf-C2H2_9 PF16293.5 RJW68523.1 - 0.03 14.2 15.1 0.15 11.9 0.4 4.7 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) LAS2 PF15792.5 RJW68523.1 - 0.039 14.5 0.4 2.6 8.6 0.1 3.0 2 0 0 2 2 2 0 Lung adenoma susceptibility protein 2 zf-C2H2_2 PF12756.7 RJW68523.1 - 0.054 13.8 25.1 25 5.3 0.0 6.7 4 1 2 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 RJW68523.1 - 0.091 12.7 14.9 0.33 10.9 0.1 5.0 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 RJW68523.1 - 0.12 12.6 0.1 0.12 12.6 0.1 6.6 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 RJW68523.1 - 0.23 12.2 27.8 1.4 9.6 0.1 6.8 5 1 2 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 RJW68523.1 - 0.5 10.2 30.0 0.95 9.3 0.3 6.1 5 0 0 5 5 5 0 zinc-finger C2H2-type Elf1 PF05129.13 RJW68523.1 - 3.2 7.9 20.2 0.5 10.5 1.4 5.2 3 1 1 5 5 5 0 Transcription elongation factor Elf1 like Zn-C2H2_12 PF18112.1 RJW68523.1 - 4.2 7.9 13.9 3 8.4 0.1 4.5 5 0 0 5 5 4 0 Autophagy receptor zinc finger-C2H2 domain Rad60-SLD PF11976.8 RJW68525.1 - 3.5e-21 74.8 0.0 4.1e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RJW68525.1 - 6.1e-11 41.9 0.0 6.9e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family ThiS PF02597.20 RJW68525.1 - 0.067 13.8 0.0 0.091 13.4 0.0 1.4 1 1 0 1 1 1 0 ThiS family RVT_1 PF00078.27 RJW68526.1 - 0.12 11.9 0.0 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L22e PF01776.17 RJW68527.1 - 2.7e-40 137.1 4.9 4e-40 136.6 4.9 1.2 1 0 0 1 1 1 1 Ribosomal L22e protein family PDEase_I PF00233.19 RJW68529.1 - 2.4e-72 243.5 1.0 4e-72 242.8 1.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RJW68529.1 - 5e-20 72.5 0.0 1.7e-13 51.3 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 RJW68529.1 - 1.1e-09 38.7 0.0 4.6e-06 27.0 0.0 3.3 2 1 0 2 2 2 2 GAF domain Yos9_DD PF17880.1 RJW68529.1 - 0.018 15.1 0.2 0.087 12.9 0.0 2.2 2 0 0 2 2 2 0 Yos9 dimerzation domain MatE PF01554.18 RJW68532.1 - 9.3e-55 184.7 23.9 3e-28 98.5 6.5 2.7 3 0 0 3 3 3 2 MatE Pou PF00157.17 RJW68533.1 - 7.2e-30 102.8 0.0 1.7e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 RJW68533.1 - 4.5e-18 64.8 4.4 1e-17 63.7 4.4 1.7 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 RJW68533.1 - 0.00052 20.3 0.6 0.0083 16.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain Homeobox_KN PF05920.11 RJW68533.1 - 0.0092 15.9 0.1 0.035 14.0 0.1 2.1 1 0 0 1 1 1 1 Homeobox KN domain DUF2856 PF11043.8 RJW68533.1 - 0.1 12.7 0.6 0.94 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) zf-RING_10 PF16685.5 RJW68534.1 - 0.0024 18.0 5.6 6 7.1 0.2 3.3 3 0 0 3 3 3 3 zinc RING finger of MSL2 DNA_pol_B_exo1 PF03104.19 RJW68534.1 - 0.099 11.8 0.8 0.34 10.0 0.7 1.7 1 1 1 2 2 2 0 DNA polymerase family B, exonuclease domain Pox_M2 PF04887.12 RJW68534.1 - 0.17 11.4 2.1 2.1 7.8 0.2 2.1 1 1 1 2 2 2 0 Poxvirus M2 protein MLTD_N PF06474.12 RJW68534.1 - 0.19 11.9 1.8 1.1 9.5 0.0 3.1 4 0 0 4 4 4 0 MltD lipid attachment motif MTBP_mid PF14919.6 RJW68534.1 - 2.5 7.2 4.1 10 5.2 0.3 2.1 1 1 1 2 2 2 0 MDM2-binding zf-C3HC4 PF00097.25 RJW68534.1 - 2.5 8.0 6.4 9.9 6.1 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Kelch_1 PF01344.25 RJW68535.1 - 1.4e-14 53.4 0.7 0.0079 15.8 0.1 6.3 7 0 0 7 7 7 4 Kelch motif BACK PF07707.15 RJW68535.1 - 2e-13 50.3 3.2 3.4e-13 49.6 3.2 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 RJW68535.1 - 2.3e-10 40.5 2.7 0.14 12.5 0.0 5.7 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RJW68535.1 - 7.2e-10 38.8 4.7 0.0024 18.1 0.6 5.9 4 2 2 6 6 6 3 Kelch motif Kelch_5 PF13854.6 RJW68535.1 - 3.1e-09 36.6 0.8 0.35 10.9 0.2 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 RJW68535.1 - 5e-09 36.0 0.0 0.005 16.8 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 RJW68535.1 - 3.8e-07 29.8 0.1 0.69 10.0 0.0 4.7 4 0 0 4 4 4 2 Kelch motif BAG6 PF12057.8 RJW68536.1 - 0.031 13.9 3.7 2.8 7.7 0.3 3.2 3 0 0 3 3 3 0 BCL2-associated athanogene 6 Dicty_REP PF05086.12 RJW68536.1 - 0.57 8.1 0.7 0.91 7.4 0.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3509 PF12021.8 RJW68537.1 - 0.013 15.3 0.1 0.034 13.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) DivIVA PF05103.13 RJW68542.1 - 0.81 9.8 3.2 17 5.5 0.2 2.3 2 0 0 2 2 2 0 DivIVA protein EzrA PF06160.12 RJW68542.1 - 0.87 7.7 3.5 4.7 5.3 0.8 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA SKA1 PF07160.12 RJW68542.1 - 0.88 9.4 3.0 1 9.1 0.4 1.9 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 SlyX PF04102.12 RJW68542.1 - 2.3 8.9 6.1 2.4 8.8 0.1 2.9 2 1 0 2 2 2 0 SlyX Biotin_lipoyl PF00364.22 RJW68543.1 - 4.6e-07 29.6 0.0 9.1e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-synt_S1 PF05827.12 RJW68543.1 - 0.066 13.0 0.4 0.15 11.9 0.1 1.7 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) CAP_N PF01213.19 RJW68543.1 - 0.084 12.3 2.5 0.17 11.3 2.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Annexin PF00191.20 RJW68544.1 - 2.3e-92 303.1 9.7 7.1e-24 83.7 0.1 4.1 4 0 0 4 4 4 4 Annexin RNA_binding PF01877.17 RJW68544.1 - 0.11 12.8 0.7 0.44 10.8 0.1 2.1 2 1 0 2 2 2 0 RNA binding Sigma70_ner PF04546.13 RJW68544.1 - 0.35 10.7 1.9 2.6 7.9 0.0 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region Tubulin PF00091.25 RJW68545.1 - 2e-28 99.9 0.0 2.4e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain PCI PF01399.27 RJW68546.1 - 2e-23 82.9 0.1 6e-23 81.4 0.1 1.9 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.11 RJW68546.1 - 8.9e-21 74.1 0.4 2.2e-20 72.8 0.4 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 RJW68546.1 - 0.02 15.0 3.7 0.05 13.7 1.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 RJW68546.1 - 1.8 9.1 6.2 10 6.7 0.5 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 RJW68548.1 - 1e-22 79.5 22.1 4.2e-07 30.1 3.3 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 RJW68548.1 - 6.6e-20 70.4 29.2 7.1e-06 26.2 1.4 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW68548.1 - 2.4e-12 46.5 27.5 0.0048 17.6 1.2 5.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW68548.1 - 0.00056 19.6 21.8 0.018 14.8 1.2 5.3 5 0 0 5 5 5 2 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 RJW68548.1 - 0.016 16.0 7.7 0.3 11.9 0.5 2.6 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 RJW68548.1 - 0.086 13.2 12.3 0.49 10.7 0.0 4.2 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 RJW68548.1 - 0.22 11.7 12.9 2 8.6 1.9 2.8 2 0 0 2 2 2 0 Zinc ribbon domain COX5B PF01215.19 RJW68548.1 - 0.27 10.9 4.4 0.89 9.3 0.5 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Vb zf-C2H2_2 PF12756.7 RJW68548.1 - 0.28 11.6 17.8 6.1 7.3 0.3 4.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 RJW68548.1 - 3.2 7.9 11.6 69 3.7 0.2 4.7 2 1 3 5 5 5 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 RJW68548.1 - 5.7 7.0 24.3 0.9 9.6 2.1 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger Synapsin PF02078.16 RJW68549.1 - 3.8e-40 136.2 0.0 6.2e-40 135.6 0.0 1.3 1 0 0 1 1 1 1 Synapsin, N-terminal domain Synapsin_C PF02750.14 RJW68549.1 - 1.9e-38 132.1 0.0 2.6e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain gerPA PF10676.9 RJW68549.1 - 0.094 13.0 1.6 0.28 11.5 0.8 2.2 1 1 1 2 2 2 0 Spore germination protein gerPA/gerPF PIN_8 PF18476.1 RJW68549.1 - 0.23 11.3 0.3 0.36 10.7 0.3 1.2 1 0 0 1 1 1 0 PIN like domain Annexin PF00191.20 RJW68550.1 - 3.1e-92 302.6 12.8 4.2e-24 84.4 0.2 4.1 4 0 0 4 4 4 4 Annexin GP24_25 PF17388.2 RJW68550.1 - 0.026 14.5 0.3 1.6 8.7 0.1 2.7 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 Sigma70_ner PF04546.13 RJW68550.1 - 0.043 13.7 2.5 1.5 8.6 0.4 2.4 2 1 0 2 2 2 0 Sigma-70, non-essential region CH PF00307.31 RJW68551.1 - 1.1e-28 99.6 0.0 2.6e-14 53.3 0.2 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW68551.1 - 1.2e-07 31.5 0.0 0.00036 20.3 0.0 3.4 2 2 2 4 4 4 2 CAMSAP CH domain CH_2 PF06294.11 RJW68551.1 - 1.3e-06 28.4 0.0 3.5e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 CH-like domain in sperm protein cNMP_binding PF00027.29 RJW68552.1 - 2.5e-40 136.5 0.2 2.9e-19 68.9 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 RJW68552.1 - 1.6e-06 27.7 0.1 3.3e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Annexin PF00191.20 RJW68553.1 - 5.4e-87 285.9 13.7 4.8e-23 81.0 0.0 4.3 4 0 0 4 4 4 4 Annexin DUF778 PF05608.12 RJW68553.1 - 0.031 14.6 0.3 0.059 13.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF778) APT PF03440.14 RJW68553.1 - 0.055 13.4 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain RR_TM4-6 PF06459.12 RJW68553.1 - 0.76 9.6 7.1 1.9 8.3 7.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec1 PF00995.23 RJW68555.1 - 2.3e-102 344.1 0.0 3.1e-102 343.7 0.0 1.1 1 0 0 1 1 1 1 Sec1 family FAM221 PF14753.6 RJW68557.1 - 7.4e-27 94.2 15.9 3.4e-25 88.8 15.9 2.1 1 1 0 1 1 1 1 Protein FAM221A/B Annexin PF00191.20 RJW68558.1 - 1.4e-95 313.4 7.3 3.2e-25 88.0 0.1 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 RJW68558.1 - 0.0035 17.2 1.1 0.55 10.2 0.0 3.6 4 0 0 4 4 4 1 Myb DNA-binding like Sigma70_ner PF04546.13 RJW68558.1 - 0.004 17.1 1.1 0.004 17.1 1.1 2.2 2 1 0 3 3 3 1 Sigma-70, non-essential region DUF1887 PF09002.11 RJW68558.1 - 0.092 11.4 0.2 0.15 10.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Mlh1_C PF16413.5 RJW68559.1 - 1.7e-73 247.3 0.0 3.4e-73 246.3 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 RJW68559.1 - 5.4e-20 71.3 0.0 4.1e-11 42.6 0.0 2.5 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 RJW68559.1 - 6.8e-11 42.1 0.0 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RJW68559.1 - 1.3e-06 28.9 0.0 2.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PBD PF00786.28 RJW68560.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Ras PF00071.22 RJW68561.1 - 5.5e-36 123.6 0.0 6.6e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW68561.1 - 1.1e-09 38.6 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW68561.1 - 0.0093 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW68561.1 - 0.042 13.4 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain cNMP_binding PF00027.29 RJW68562.1 - 6.4e-38 128.7 0.1 1.3e-17 63.6 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 RJW68562.1 - 6.7e-07 28.9 0.1 1.7e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit ArfGap PF01412.18 RJW68564.1 - 9.5e-33 112.7 0.1 2.6e-32 111.4 0.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 RJW68564.1 - 4.1e-14 53.0 0.1 4.4e-06 27.2 0.0 3.2 3 0 0 3 3 3 2 PH domain Ank_2 PF12796.7 RJW68564.1 - 5.5e-11 42.9 0.2 1.9e-09 38.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) BAR_3 PF16746.5 RJW68564.1 - 7.4e-11 42.2 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 BAR domain of APPL family Ank_4 PF13637.6 RJW68564.1 - 7.1e-08 32.8 0.8 3.3e-07 30.7 0.5 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW68564.1 - 2e-07 30.8 0.1 0.018 15.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RJW68564.1 - 4.5e-07 30.0 1.3 4.5e-05 23.7 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RJW68564.1 - 2.4e-06 27.7 2.3 0.1 13.1 0.3 4.1 3 1 0 3 3 3 2 Ankyrin repeat PH_11 PF15413.6 RJW68564.1 - 0.015 15.8 1.7 0.28 11.6 1.7 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain TF_AP-2 PF03299.14 RJW68565.1 - 3.1e-21 76.3 0.1 5.3e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Transcription factor AP-2 Mito_carr PF00153.27 RJW68566.1 - 4.5e-52 174.0 0.5 1.7e-18 66.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4201 PF13870.6 RJW68567.1 - 0.037 13.7 5.5 0.073 12.8 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF5129 PF17173.4 RJW68567.1 - 0.061 12.4 0.5 0.1 11.7 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5129) zf-H2C2_5 PF13909.6 RJW68568.1 - 2.3e-07 30.4 7.8 2.7e-05 23.8 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain OrsD PF12013.8 RJW68568.1 - 0.019 15.4 1.2 0.34 11.4 0.2 2.5 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_12 PF18658.1 RJW68568.1 - 0.051 13.2 0.7 0.11 12.1 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type RMP PF14996.6 RJW68568.1 - 0.13 12.4 0.9 0.82 9.9 0.8 2.3 1 1 1 2 2 2 0 Retinal Maintenance zf-met2 PF12907.7 RJW68568.1 - 0.18 12.0 0.2 0.18 12.0 0.2 2.0 2 0 0 2 2 2 0 Zinc-binding zf_C2H2_ZHX PF18387.1 RJW68568.1 - 0.21 11.2 3.9 0.67 9.6 0.2 2.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 RJW68568.1 - 9.5 6.9 5.8 55 4.5 0.4 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 RJW68569.1 - 1.6e-13 50.3 39.9 0.00037 20.8 2.0 6.3 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW68569.1 - 6.3e-09 35.9 4.6 1.2e-06 28.7 0.8 5.0 5 0 0 5 5 5 2 Zinc-finger double domain GAGA PF09237.11 RJW68569.1 - 0.016 15.0 0.2 0.16 11.8 0.0 2.5 2 0 0 2 2 2 0 GAGA factor zf-C2H2_4 PF13894.6 RJW68569.1 - 0.036 14.9 35.6 0.12 13.2 0.3 6.6 6 0 0 6 6 6 0 C2H2-type zinc finger FOXP-CC PF16159.5 RJW68569.1 - 0.041 14.5 19.4 0.11 13.1 0.6 5.5 2 1 3 5 5 5 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 RJW68569.1 - 1.1 9.3 9.2 4 7.5 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RJW68569.1 - 1.2 9.2 13.7 4.7 7.3 0.7 3.9 1 1 2 4 4 4 0 Aberrant zinc-finger Zap1_zf2 PF18217.1 RJW68569.1 - 3.7 7.6 7.6 0.31 11.1 1.0 2.6 2 0 0 2 2 2 0 Zap1 zinc finger 2 DUF953 PF06110.11 RJW68570.1 - 8.1e-29 99.7 0.0 1.5e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 RJW68570.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.20 RJW68570.1 - 0.034 14.1 0.1 0.33 11.0 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin RBD-FIP PF09457.10 RJW68571.1 - 7.2e-10 38.6 0.5 2.2e-09 37.1 0.5 1.9 1 0 0 1 1 1 1 FIP domain EF-hand_7 PF13499.6 RJW68571.1 - 1.4e-07 31.9 0.1 1.4e-07 31.9 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW68571.1 - 2.9e-05 23.7 3.8 0.069 13.1 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 RJW68571.1 - 3.2e-05 23.2 4.1 0.15 11.7 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 RJW68571.1 - 0.00057 19.7 4.7 0.2 11.6 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain pair TMF_TATA_bd PF12325.8 RJW68571.1 - 0.0049 17.1 12.8 0.0049 17.1 12.8 3.9 2 2 2 4 4 4 1 TATA element modulatory factor 1 TATA binding Tho2 PF11262.8 RJW68571.1 - 1.1 8.4 24.8 0.071 12.3 8.1 2.6 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 FUSC PF04632.12 RJW68571.1 - 2.5 6.5 16.6 0.12 10.9 9.9 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family Nbl1_Borealin_N PF10444.9 RJW68571.1 - 4.1 7.1 12.0 1.8 8.3 0.2 4.0 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal PRA-PH PF01503.17 RJW68571.1 - 4.2 7.9 7.5 3 8.4 0.2 2.6 1 1 1 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase NTF2 PF02136.20 RJW68572.1 - 0.82 10.2 3.0 31 5.2 0.0 3.4 3 0 0 3 3 3 0 Nuclear transport factor 2 (NTF2) domain HAD PF12710.7 RJW68576.1 - 4e-12 46.9 0.0 5.4e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RJW68576.1 - 5.2e-07 30.2 0.0 6.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 RJW68576.1 - 0.0088 15.6 0.0 0.014 15.0 0.0 1.3 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase_3 PF08282.12 RJW68576.1 - 0.0097 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cytochrom_B561 PF03188.16 RJW68577.1 - 2.9e-34 118.1 4.2 2.9e-34 118.1 4.2 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.20 RJW68577.1 - 0.017 14.7 9.7 0.03 13.9 9.7 1.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Ferric_reduct PF01794.19 RJW68577.1 - 0.45 10.6 8.0 5.8 7.1 5.9 2.4 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF4079 PF13301.6 RJW68577.1 - 3.1 7.9 10.4 11 6.2 5.4 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) EF-hand_7 PF13499.6 RJW68581.1 - 2.3e-19 69.6 4.6 1.6e-10 41.2 0.6 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RJW68581.1 - 3.6e-19 66.8 3.3 4.4e-06 25.9 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RJW68581.1 - 3e-16 57.9 4.9 6.8e-05 22.5 0.2 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RJW68581.1 - 9.6e-12 43.8 2.4 0.00042 19.7 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RJW68581.1 - 3.4e-09 36.4 7.4 4.6e-05 23.2 0.3 4.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 RJW68581.1 - 0.019 14.9 1.7 4.5 7.3 0.0 3.2 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RJW68581.1 - 0.023 15.0 1.1 0.92 9.8 0.2 3.2 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RJW68581.1 - 0.033 14.5 0.0 10 6.5 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 RJW68581.1 - 0.61 10.0 2.9 36 4.3 0.1 3.4 4 0 0 4 4 4 0 EF hand Complex1_LYR_2 PF13233.6 RJW68582.1 - 1.6e-06 28.7 0.3 2.3e-06 28.2 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Dimer_Tnp_hAT PF05699.14 RJW68583.1 - 1.1e-07 31.5 0.0 4.9e-07 29.5 0.0 2.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RJW68583.1 - 8e-07 29.0 0.3 1.9e-06 27.8 0.3 1.7 1 0 0 1 1 1 1 BED zinc finger Blt1 PF12754.7 RJW68583.1 - 0.076 13.3 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Blt1 N-terminal domain Aminotran_3 PF00202.21 RJW68584.1 - 2.2e-66 224.2 0.0 2.5e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pou PF00157.17 RJW68586.1 - 2.6e-29 101.0 0.0 5.9e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 RJW68586.1 - 1.9e-16 59.6 2.3 4.6e-16 58.4 2.3 1.7 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 RJW68586.1 - 0.0015 18.9 0.0 0.0032 17.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Homeobox_KN PF05920.11 RJW68586.1 - 0.095 12.6 0.2 0.32 10.9 0.2 1.9 1 0 0 1 1 1 0 Homeobox KN domain zf-BED PF02892.15 RJW68588.1 - 5.7e-05 23.1 0.4 0.00012 22.0 0.4 1.6 1 0 0 1 1 1 1 BED zinc finger AT_hook PF02178.19 RJW68588.1 - 0.34 10.9 6.5 4.3 7.5 2.2 2.9 2 0 0 2 2 2 0 AT hook motif SPR1 PF15356.6 RJW68588.1 - 2.4 8.7 7.5 5.4 7.6 0.2 3.0 3 0 0 3 3 3 0 Psoriasis susceptibility locus 2 Ig_3 PF13927.6 RJW68589.1 - 0.0066 17.0 0.0 0.0066 17.0 0.0 4.0 5 0 0 5 5 5 1 Immunoglobulin domain ig PF00047.25 RJW68589.1 - 0.035 14.3 1.1 0.42 10.8 0.0 2.8 2 0 0 2 2 2 0 Immunoglobulin domain fn3 PF00041.21 RJW68589.1 - 0.11 12.8 1.8 42 4.6 0.0 4.1 4 0 0 4 4 4 0 Fibronectin type III domain TEA PF01285.18 RJW68590.1 - 5.3e-27 93.7 0.1 8.2e-27 93.1 0.1 1.3 1 0 0 1 1 1 1 TEA/ATTS domain PI3_PI4_kinase PF00454.27 RJW68592.1 - 1.2e-39 136.6 0.0 7.5e-38 130.8 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 RJW68592.1 - 5.7e-09 35.7 0.0 1.6e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 RJW68592.1 - 0.0012 18.2 0.1 0.85 8.8 0.0 2.7 2 0 0 2 2 2 2 FAT domain SMC_N PF02463.19 RJW68593.1 - 2.8e-68 229.6 0.1 1.1e-36 126.4 0.2 2.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RJW68593.1 - 8.7e-25 87.3 0.1 8.7e-25 87.3 0.1 3.3 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 RJW68593.1 - 2.7e-13 50.9 0.8 2.7e-13 50.9 0.8 6.5 3 2 2 5 5 5 1 AAA domain AAA_21 PF13304.6 RJW68593.1 - 1.4e-12 48.1 1.8 2.4e-05 24.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RJW68593.1 - 3.7e-09 36.8 6.7 3.7e-09 36.8 6.7 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 RJW68593.1 - 0.00013 21.6 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF948 PF06103.11 RJW68593.1 - 0.0062 16.8 3.8 0.0062 16.8 3.8 5.4 3 2 1 4 4 4 1 Bacterial protein of unknown function (DUF948) ABC_tran PF00005.27 RJW68593.1 - 0.041 14.4 0.0 0.041 14.4 0.0 6.1 4 2 2 6 6 6 0 ABC transporter RED_C PF07807.11 RJW68593.1 - 0.57 10.7 5.5 0.48 10.9 1.7 3.0 2 0 0 2 2 2 0 RED-like protein C-terminal region PDZ PF00595.24 RJW68594.1 - 3.4e-13 49.8 0.1 8.4e-13 48.5 0.0 1.6 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 RJW68594.1 - 6.9e-11 41.8 0.1 1.1e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW68594.1 - 8.8e-08 32.4 0.1 3.5e-07 30.4 0.0 1.9 1 1 1 2 2 2 1 PDZ domain Dimer_Tnp_hAT PF05699.14 RJW68595.1 - 3.6e-09 36.3 0.1 9.9e-09 34.9 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SET PF00856.28 RJW68596.1 - 2.6e-17 63.7 0.2 3.8e-16 59.9 0.0 2.6 2 1 0 2 2 2 1 SET domain DUF2956 PF11169.8 RJW68596.1 - 0.0036 17.5 0.9 0.0036 17.5 0.9 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2956) RhoGAP PF00620.27 RJW68597.1 - 4.9e-14 52.4 0.0 7.5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain rve PF00665.26 RJW68597.1 - 3.1e-11 43.5 0.0 6.1e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain SPATA1_C PF15743.5 RJW68599.1 - 5.3e-21 75.3 69.7 1.3e-15 57.8 37.4 3.5 3 1 0 3 3 3 2 Spermatogenesis-associated C-terminus OmpH PF03938.14 RJW68599.1 - 0.011 16.0 12.2 0.011 16.0 12.2 5.1 4 2 2 6 6 6 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 RJW68599.1 - 6 7.3 10.4 38 4.8 0.3 4.6 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) polyprenyl_synt PF00348.17 RJW68600.1 - 3.2e-74 249.2 0.0 4e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase polyprenyl_synt PF00348.17 RJW68601.1 - 7.6e-74 248.0 0.0 9.2e-74 247.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1908 PF08926.11 RJW68603.1 - 2.8e-73 246.5 0.0 2.8e-73 246.5 0.0 5.1 4 1 0 4 4 3 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 RJW68603.1 - 4.3e-59 200.0 0.0 6.2e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68603.1 - 8.3e-28 97.4 0.0 2.1e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 RJW68603.1 - 9.6e-09 35.0 0.0 1.9e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW68603.1 - 4.1e-08 33.4 0.0 9.2e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 RJW68603.1 - 6.2e-05 23.0 0.0 0.013 15.4 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RJW68603.1 - 0.00045 19.6 0.1 0.0013 18.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PDZ_2 PF13180.6 RJW68603.1 - 0.00082 19.6 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Haspin_kinase PF12330.8 RJW68603.1 - 0.0055 15.7 0.3 0.0055 15.7 0.3 2.3 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_C PF00433.24 RJW68603.1 - 0.028 15.1 3.0 0.97 10.2 3.0 3.7 1 1 0 1 1 1 0 Protein kinase C terminal domain Pkinase_fungal PF17667.1 RJW68603.1 - 0.057 12.2 0.0 0.14 10.9 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Acyl-CoA_dh_1 PF00441.24 RJW68604.1 - 2.3e-46 157.7 1.4 3.3e-46 157.2 1.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 RJW68604.1 - 1.4e-25 90.1 0.2 2.1e-25 89.6 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RJW68604.1 - 1.1e-24 86.4 0.0 2e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RJW68604.1 - 4.4e-17 62.8 0.0 3e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.6 RJW68604.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Nup35_RRM PF05172.13 RJW68606.1 - 8.4e-21 73.8 0.0 1.9e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 RJW68606.1 - 2.8e-09 36.8 0.0 4.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TraB PF01963.17 RJW68608.1 - 9.7e-50 169.9 0.0 5.1e-34 118.4 0.0 3.0 2 1 0 2 2 2 2 TraB family DUF3611 PF12263.8 RJW68609.1 - 0.17 11.7 0.5 0.39 10.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) TRAM_LAG1_CLN8 PF03798.16 RJW68610.1 - 6.1e-21 75.1 18.6 6.1e-21 75.1 18.6 1.5 2 0 0 2 2 2 1 TLC domain RhoGAP PF00620.27 RJW68611.1 - 3e-36 124.5 0.0 9.4e-36 122.9 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain C2 PF00168.30 RJW68611.1 - 0.00059 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain PDEase_I PF00233.19 RJW68612.1 - 0.068 12.9 0.1 0.068 12.9 0.1 1.1 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase HTH_41 PF14502.6 RJW68612.1 - 0.092 12.4 0.0 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TPX2 PF06886.11 RJW68614.1 - 1.4e-12 47.7 13.6 1.4e-12 47.7 13.6 1.5 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) Rrp15p PF07890.12 RJW68615.1 - 1.4e-23 83.7 1.3 2.6e-23 82.8 1.3 1.4 1 0 0 1 1 1 1 Rrp15p p25-alpha PF05517.12 RJW68616.1 - 0.00019 21.7 0.0 0.00019 21.6 0.0 1.0 1 0 0 1 1 1 1 p25-alpha EF-hand_8 PF13833.6 RJW68618.1 - 1e-12 47.7 0.6 9.7e-08 31.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW68618.1 - 1.5e-11 43.0 7.7 2.3e-05 23.6 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RJW68618.1 - 9.6e-11 40.7 5.7 0.00022 20.9 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 RJW68618.1 - 5.9e-10 38.2 2.4 3.6e-05 23.1 0.6 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW68618.1 - 1e-06 29.1 9.5 0.0026 18.2 4.5 3.8 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_4 PF12763.7 RJW68618.1 - 3.2e-05 23.8 0.3 0.36 10.8 0.0 3.1 4 0 0 4 4 4 2 Cytoskeletal-regulatory complex EF hand LUC7 PF03194.15 RJW68621.1 - 5.7e-74 249.0 6.4 5.7e-74 249.0 6.4 1.5 1 1 0 1 1 1 1 LUC7 N_terminus Seryl_tRNA_N PF02403.22 RJW68621.1 - 0.0015 18.7 5.1 0.005 17.1 5.1 1.9 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CP12 PF02672.15 RJW68621.1 - 0.33 11.7 0.2 0.33 11.7 0.2 3.1 3 0 0 3 3 3 0 CP12 domain PP-binding PF00550.25 RJW68624.1 - 1.2e-11 44.8 0.1 1.9e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACBP PF00887.19 RJW68625.1 - 3.7e-33 113.6 0.9 8.3e-33 112.5 0.9 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein ECH_1 PF00378.20 RJW68625.1 - 9.8e-21 74.2 0.0 1.8e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RJW68625.1 - 3.7e-16 59.5 0.0 1.1e-15 58.0 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Pox_P4B PF03292.14 RJW68625.1 - 0.23 9.7 0.0 0.31 9.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein MFS_1 PF07690.16 RJW68626.1 - 5.8e-20 71.5 26.0 6.9e-18 64.7 13.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 RJW68628.1 - 5.2e-18 65.4 0.0 1.2e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW68628.1 - 1.3e-16 60.9 0.0 2.3e-15 56.9 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW68628.1 - 3.8e-15 56.3 0.0 6.4e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RJW68628.1 - 0.074 13.3 0.0 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain L27_2 PF09045.10 RJW68628.1 - 0.085 12.8 0.2 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 L27_2 EF-hand_7 PF13499.6 RJW68629.1 - 4.3e-19 68.7 2.1 1.4e-15 57.5 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW68629.1 - 3.4e-15 54.4 7.6 5.3e-09 35.0 0.8 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RJW68629.1 - 9.1e-14 51.0 8.1 2.4e-12 46.5 0.3 3.2 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW68629.1 - 1.6e-11 43.2 7.2 4.3e-05 23.1 0.2 3.8 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 RJW68629.1 - 2.1e-08 33.3 6.0 2.6e-05 23.5 0.4 3.2 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 RJW68629.1 - 2.2e-05 24.7 0.1 8e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 RJW68629.1 - 0.007 16.3 2.0 0.23 11.4 0.1 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand FGAR-AT_linker PF18072.1 RJW68629.1 - 0.034 14.7 0.6 23 5.6 0.1 3.1 2 2 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain ICAT PF06384.11 RJW68629.1 - 0.057 13.7 0.3 0.66 10.3 0.0 2.2 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Mito_carr PF00153.27 RJW68630.1 - 1.7e-44 149.7 4.5 6.9e-17 61.2 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DDE_Tnp_IS1595 PF12762.7 RJW68631.1 - 2.4e-08 34.1 0.0 4.4e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS1 PF03400.13 RJW68631.1 - 0.0036 17.6 0.0 0.0059 17.0 0.0 1.3 1 0 0 1 1 1 1 IS1 transposase aGPT-Pplase1 PF18723.1 RJW68631.1 - 0.051 13.0 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 ASH PF15780.5 RJW68632.1 - 1.8e-26 92.2 12.4 0.00026 21.1 0.0 9.9 10 0 0 10 10 10 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RJW68632.1 - 1.4e-07 31.6 0.9 0.021 15.0 0.0 5.8 5 1 1 6 6 6 1 Flagellar-associated PapD-like DUF1573 PF07610.11 RJW68632.1 - 1.4e-07 31.5 0.6 0.31 11.1 0.0 5.9 6 0 0 6 6 6 2 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 RJW68632.1 - 5e-07 29.5 0.6 3.7 7.4 0.0 7.4 8 1 1 9 9 9 1 MSP (Major sperm protein) domain PapD_N PF00345.20 RJW68632.1 - 0.34 10.8 4.2 0.5 10.3 0.0 3.5 5 0 0 5 5 5 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Scaffolding_pro PF11418.8 RJW68632.1 - 1 10.0 4.8 0.95 10.1 0.9 2.8 2 0 0 2 2 2 0 Phi29 scaffolding protein Clathrin PF00637.20 RJW68633.1 - 3.8e-13 49.5 24.8 0.0026 17.6 0.0 8.3 6 3 1 7 7 7 5 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 RJW68633.1 - 1.4e-10 41.3 0.1 0.033 14.5 0.0 6.0 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW68633.1 - 5.5e-07 30.2 1.7 0.026 15.4 0.0 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 RJW68633.1 - 1.6e-05 24.2 21.3 0.016 14.3 0.9 5.6 4 1 1 5 5 5 4 Coatomer WD associated region TPR_8 PF13181.6 RJW68633.1 - 0.0011 19.0 25.2 0.11 12.8 0.5 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat eIF2A PF08662.11 RJW68633.1 - 0.0071 16.2 0.1 0.96 9.3 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A TPR_11 PF13414.6 RJW68633.1 - 0.082 12.6 2.6 16 5.3 0.1 5.6 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.28 RJW68633.1 - 0.14 12.0 32.8 0.38 10.7 0.5 9.9 11 2 1 12 12 12 0 Tetratricopeptide repeat PPR PF01535.20 RJW68633.1 - 7.7 7.0 14.2 60 4.2 0.1 7.6 9 0 0 9 9 9 0 PPR repeat Mcm10 PF09332.11 RJW68636.1 - 1.2e-40 140.1 3.9 1.2e-40 140.1 3.9 3.3 3 1 0 3 3 3 1 Mcm10 replication factor zf-primase PF09329.11 RJW68636.1 - 7.7e-14 51.2 1.0 2.4e-13 49.7 1.0 1.9 1 0 0 1 1 1 1 Primase zinc finger R3H PF01424.22 RJW68636.1 - 6.1 6.9 5.6 0.73 9.9 0.1 2.4 3 0 0 3 3 3 0 R3H domain TFIIA_gamma_C PF02751.14 RJW68637.1 - 4.5e-21 74.7 0.4 7.8e-21 74.0 0.4 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 RJW68637.1 - 1.9e-14 53.4 1.3 7.6e-12 45.1 0.2 2.2 2 0 0 2 2 2 2 Transcription initiation factor IIA, gamma subunit, helical domain DUF3886 PF13025.6 RJW68637.1 - 0.03 14.5 0.6 0.053 13.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Tom37 PF10568.9 RJW68638.1 - 3.1e-09 37.2 0.0 4.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 RJW68638.1 - 0.00036 20.3 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RJW68638.1 - 0.0009 20.0 0.0 0.0021 18.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain zf-C2H2_4 PF13894.6 RJW68642.1 - 2e-07 31.2 31.7 0.093 13.6 2.0 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW68642.1 - 3.3e-06 27.3 34.2 0.0081 16.6 0.8 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type DUF629 PF04780.12 RJW68642.1 - 0.12 10.9 6.2 0.77 8.2 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.8 RJW68642.1 - 0.69 10.3 9.1 1.9 8.9 0.6 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW68642.1 - 1.2 9.2 14.5 0.24 11.5 1.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3716 PF12511.8 RJW68642.1 - 1.9 8.6 5.4 6.1 7.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3716) Zf_RING PF16744.5 RJW68642.1 - 5.3 7.2 7.1 6.3 7.0 0.0 3.6 4 0 0 4 4 4 0 KIAA1045 RING finger Aldedh PF00171.22 RJW68643.1 - 1.7e-160 534.6 0.1 1.9e-160 534.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 RJW68643.1 - 0.018 14.1 0.1 0.029 13.4 0.1 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Lantibiotic_a PF14867.6 RJW68643.1 - 0.071 12.9 0.3 0.24 11.2 0.3 1.9 1 0 0 1 1 1 0 Lantibiotic alpha BMC PF00936.19 RJW68643.1 - 0.14 12.2 0.7 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 BMC domain LptF_LptG PF03739.14 RJW68644.1 - 0.01 14.7 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG ABG_transport PF03806.13 RJW68644.1 - 0.014 13.6 0.2 0.016 13.5 0.2 1.0 1 0 0 1 1 1 0 AbgT putative transporter family ODV-E18 PF10717.9 RJW68644.1 - 0.68 9.8 2.9 0.91 9.4 2.9 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RVT_1 PF00078.27 RJW68646.1 - 1.4e-28 100.0 0.0 2.8e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW68646.1 - 8.8e-07 28.8 0.0 3e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SHIPPO-rpt PF07004.12 RJW68648.1 - 1.9e-08 34.8 1.3 0.0038 18.1 0.0 3.2 3 0 0 3 3 3 2 Sperm-tail PG-rich repeat zf-C3H2C3 PF17122.5 RJW68651.1 - 0.0019 18.2 0.6 0.0055 16.7 0.6 1.8 1 0 0 1 1 1 1 Zinc-finger Fn_bind PF02986.14 RJW68651.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Fibronectin binding repeat Ribosomal_S17 PF00366.20 RJW68652.1 - 6.9e-26 90.1 5.1 9.7e-26 89.7 5.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 RJW68652.1 - 4.9e-23 81.3 5.3 4.9e-23 81.3 5.3 2.3 2 1 0 2 2 2 1 Ribosomal_S17 N-terminal PRF PF06875.11 RJW68652.1 - 0.041 13.3 0.5 0.065 12.6 0.5 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Calpain_III PF01067.22 RJW68653.1 - 2.5e-20 73.2 0.0 4.1e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_8 PF13833.6 RJW68653.1 - 6.1e-11 42.0 1.7 6.1e-11 42.0 1.7 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW68653.1 - 3.2e-08 32.5 0.6 3.7e-05 23.0 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW68653.1 - 1.5e-05 24.5 0.2 0.091 12.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 RJW68653.1 - 9.7e-05 21.7 2.1 0.03 13.8 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW68653.1 - 0.00017 22.0 0.8 0.00037 20.9 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair DUF533 PF04391.12 RJW68653.1 - 0.095 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Chromo_shadow PF01393.19 RJW68654.1 - 3e-30 104.1 0.1 7.2e-29 99.7 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 RJW68654.1 - 4.5e-22 77.7 1.0 7.8e-19 67.3 0.9 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain SRP-alpha_N PF04086.13 RJW68654.1 - 0.58 10.0 5.6 0.85 9.5 5.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Leu_zip PF15294.6 RJW68655.1 - 0.0015 18.1 8.3 0.0018 17.8 8.3 1.0 1 0 0 1 1 1 1 Leucine zipper Spc7 PF08317.11 RJW68655.1 - 0.0029 16.6 9.3 0.0041 16.1 9.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Lebercilin PF15619.6 RJW68655.1 - 0.01 15.5 13.6 0.69 9.5 8.2 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease YabA PF06156.13 RJW68655.1 - 0.011 16.4 10.2 0.07 13.8 5.1 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Sec34 PF04136.15 RJW68655.1 - 0.034 14.0 6.5 1 9.3 1.1 2.3 1 1 1 2 2 2 0 Sec34-like family Macoilin PF09726.9 RJW68655.1 - 0.062 11.9 12.3 0.39 9.2 12.3 1.8 1 1 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 RJW68655.1 - 0.099 12.2 6.9 0.12 11.9 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HMMR_N PF15905.5 RJW68655.1 - 0.13 11.7 10.3 0.44 10.0 10.4 1.7 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 RJW68655.1 - 0.16 11.3 2.9 0.21 10.9 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 RJW68655.1 - 0.21 11.6 13.4 0.084 12.9 4.6 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 RJW68655.1 - 0.29 10.6 10.4 1.5 8.2 10.3 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 RJW68655.1 - 0.31 11.3 16.5 0.38 11.0 5.2 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4472 PF14739.6 RJW68655.1 - 0.38 11.5 11.6 1.7 9.4 9.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF724 PF05266.14 RJW68655.1 - 0.39 10.5 10.7 0.14 12.0 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HALZ PF02183.18 RJW68655.1 - 0.54 10.5 14.0 0.31 11.3 3.7 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper UPF0449 PF15136.6 RJW68655.1 - 0.63 10.5 8.2 0.23 12.0 2.1 2.6 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 Cep57_MT_bd PF06657.13 RJW68655.1 - 0.64 10.5 12.6 0.33 11.4 5.4 2.7 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CENP-H PF05837.12 RJW68655.1 - 0.67 10.4 12.7 1.2 9.5 5.8 2.6 1 1 2 3 3 3 0 Centromere protein H (CENP-H) TMPIT PF07851.13 RJW68655.1 - 0.74 9.0 3.2 0.92 8.7 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein YojJ PF10372.9 RJW68655.1 - 0.89 9.7 6.4 0.38 10.9 1.2 2.3 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus JIP_LZII PF16471.5 RJW68655.1 - 1.3 9.2 14.1 7.6 6.8 6.4 3.0 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II PHM7_cyt PF14703.6 RJW68655.1 - 1.5 9.0 5.4 2.8 8.2 5.5 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter FapA PF03961.13 RJW68655.1 - 1.9 7.0 6.2 2.7 6.5 6.2 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A ATG16 PF08614.11 RJW68655.1 - 4.7 7.4 17.6 8.8 6.5 12.4 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cut12 PF11500.8 RJW68655.1 - 5 7.1 8.6 3.9 7.4 2.0 2.2 1 1 1 2 2 2 0 Spindle pole body formation-associated protein Sulfotransfer_4 PF17784.1 RJW68656.1 - 3.8e-62 209.9 0.0 4.2e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW68656.1 - 0.0011 19.4 0.0 0.0047 17.3 0.0 1.8 1 1 1 2 2 2 1 Sulfotransferase family Pkinase PF00069.25 RJW68657.1 - 1.5e-14 54.0 0.0 2.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68657.1 - 1.8e-07 30.8 0.0 3.8e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.6 RJW68658.1 - 2.8e-11 43.6 9.7 1e-10 41.8 9.7 2.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RJW68658.1 - 5e-09 36.3 7.1 1.7e-08 34.6 7.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RJW68658.1 - 4.3e-08 33.0 7.3 1.1e-07 31.7 7.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RJW68658.1 - 5.9e-07 29.2 10.3 1.5e-06 27.9 10.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW68658.1 - 2.3e-06 27.3 7.9 5.8e-06 26.1 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW68658.1 - 2.4e-05 24.2 8.4 6.6e-05 22.8 8.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RJW68658.1 - 7.6e-05 22.7 5.0 0.00019 21.5 5.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RJW68658.1 - 8.3e-05 22.4 7.3 0.00025 20.8 7.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RJW68658.1 - 0.00011 21.9 8.0 0.00031 20.4 8.0 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING-like PF08746.11 RJW68658.1 - 0.0014 18.9 9.1 0.0044 17.3 9.1 1.9 1 0 0 1 1 1 1 RING-like domain Prok-RING_4 PF14447.6 RJW68658.1 - 0.0021 17.9 9.1 0.069 13.0 9.3 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RJW68658.1 - 0.011 15.3 8.0 0.025 14.2 8.0 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 RJW68658.1 - 0.041 14.0 5.4 0.14 12.4 5.4 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RJW68658.1 - 0.079 13.2 4.9 0.4 10.9 5.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Zn-ribbon_8 PF09723.10 RJW68658.1 - 0.11 12.7 2.0 2 8.6 1.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Prok-RING_1 PF14446.6 RJW68658.1 - 0.75 9.8 13.0 0.07 13.1 6.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Rx_N PF18052.1 RJW68658.1 - 1.5 9.2 14.4 0.083 13.2 2.3 3.6 1 1 1 3 3 3 0 Rx N-terminal domain PRKG1_interact PF15898.5 RJW68658.1 - 3 8.8 22.4 11 7.0 1.4 3.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain BST2 PF16716.5 RJW68658.1 - 6.2 7.5 12.6 1.5 9.4 5.0 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 PHD PF00628.29 RJW68658.1 - 8 6.5 8.3 23 5.0 8.3 1.9 1 0 0 1 1 1 0 PHD-finger F-box-like PF12937.7 RJW68660.1 - 4.4e-09 36.1 3.6 1.1e-08 34.9 3.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RJW68660.1 - 7.6e-09 35.2 2.2 7.6e-09 35.2 2.2 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 RJW68660.1 - 1e-05 25.7 0.3 1.3 9.6 0.0 4.6 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) DZR PF12773.7 RJW68660.1 - 0.1 12.7 3.0 0.57 10.2 3.0 2.4 1 0 0 1 1 1 0 Double zinc ribbon LRR_6 PF13516.6 RJW68660.1 - 0.92 9.7 6.8 8.3 6.8 0.0 5.3 7 0 0 7 7 7 0 Leucine Rich repeat SIR2 PF02146.17 RJW68661.1 - 1.5e-41 142.3 0.0 2.6e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family RVT_1 PF00078.27 RJW68661.1 - 3.6e-18 65.9 0.0 7.3e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zinc_ribbon_9 PF14369.6 RJW68661.1 - 0.11 12.8 1.1 1.8 8.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon PDZ_6 PF17820.1 RJW68662.1 - 3e-07 30.2 0.1 7.3e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW68662.1 - 0.0005 20.4 0.0 0.00097 19.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW68662.1 - 0.0027 18.0 0.0 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain ANAPC4 PF12896.7 RJW68663.1 - 2.9e-23 82.4 3.2 5.9e-23 81.4 3.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 RJW68663.1 - 2.1e-19 69.6 0.0 2.2e-18 66.3 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW68663.1 - 0.00017 22.3 1.0 0.02 15.8 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Exostosin PF03016.15 RJW68666.1 - 2.5e-31 109.0 0.0 6.9e-31 107.6 0.0 1.8 1 1 0 1 1 1 1 Exostosin family Glyco_transf_64 PF09258.10 RJW68666.1 - 8.4e-27 94.0 0.0 1.6e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain N6-adenineMlase PF10237.9 RJW68666.1 - 5.9e-17 61.9 0.7 1.2e-16 61.0 0.7 1.5 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Corona_6B_7B PF03262.13 RJW68666.1 - 0.017 14.6 2.1 0.031 13.7 2.1 1.4 1 0 0 1 1 1 0 Coronavirus 6B/7B protein RVT_1 PF00078.27 RJW68667.1 - 4.1e-06 26.5 0.0 6.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PSP PF04046.16 RJW68669.1 - 2.6e-15 56.0 0.1 4.8e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 PSP RPA_interact_N PF14766.6 RJW68669.1 - 1.5 8.5 3.6 2.7 7.7 1.3 2.4 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Pkinase PF00069.25 RJW68670.1 - 4.1e-44 150.9 0.0 1.4e-17 64.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68670.1 - 2.4e-24 86.0 0.0 1.4e-12 47.5 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase PQQ PF01011.21 RJW68670.1 - 1.8e-05 24.4 0.5 0.11 12.5 0.0 4.2 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_2 PF13360.6 RJW68670.1 - 5.3e-05 22.9 0.0 0.00033 20.3 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain Kdo PF06293.14 RJW68670.1 - 0.0006 19.2 0.1 0.0012 18.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW68670.1 - 0.0074 16.2 0.2 0.016 15.2 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RJW68670.1 - 0.05 12.9 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PQQ_3 PF13570.6 RJW68670.1 - 0.18 12.3 0.0 46 4.7 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain RVT_1 PF00078.27 RJW68671.1 - 1.9e-45 155.1 0.0 3.3e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNAP PF14938.6 RJW68672.1 - 3.8e-92 308.7 14.1 4.2e-92 308.5 14.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 RJW68672.1 - 1.8e-08 34.5 8.0 0.0056 16.9 0.4 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW68672.1 - 5.4e-06 26.1 10.2 0.45 10.8 0.4 5.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW68672.1 - 2.4e-05 24.0 3.8 7.7 6.8 0.7 5.1 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW68672.1 - 9.2e-05 22.0 3.9 0.00014 21.4 3.9 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 RJW68672.1 - 0.0001 21.9 6.6 11 6.1 0.5 6.1 6 1 1 7 7 7 0 Tetratricopeptide repeat NSF PF02071.20 RJW68672.1 - 0.00065 19.9 21.1 0.18 12.6 0.8 6.4 6 0 0 6 6 6 2 Aromatic-di-Alanine (AdAR) repeat TPR_19 PF14559.6 RJW68672.1 - 0.0014 19.1 4.0 0.068 13.7 0.9 4.0 3 2 1 5 5 5 1 Tetratricopeptide repeat FliS PF02561.14 RJW68672.1 - 0.0017 18.6 4.6 0.086 13.1 0.2 3.7 2 1 1 4 4 4 1 Flagellar protein FliS TPR_10 PF13374.6 RJW68672.1 - 0.003 17.4 1.3 3.6 7.6 0.0 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW68672.1 - 0.0042 17.3 6.4 0.02 15.1 0.5 3.4 1 1 3 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4368 PF14287.6 RJW68672.1 - 0.014 15.7 0.7 0.067 13.5 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4368) TPR_8 PF13181.6 RJW68672.1 - 0.038 14.2 7.2 26 5.3 0.0 5.2 5 1 0 5 5 4 0 Tetratricopeptide repeat Sel1 PF08238.12 RJW68672.1 - 0.051 14.3 0.2 1.2 10.0 0.0 3.0 3 0 0 3 3 3 0 Sel1 repeat DUF357 PF04010.13 RJW68672.1 - 0.055 13.6 2.3 0.94 9.6 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF357) TPR_16 PF13432.6 RJW68672.1 - 0.056 14.1 3.1 0.21 12.2 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 RJW68672.1 - 0.079 12.7 8.1 2 8.1 8.1 2.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Spatacsin_C PF14649.6 RJW68672.1 - 0.099 11.7 9.8 0.57 9.2 8.1 2.6 1 1 1 2 2 2 0 Spatacsin C-terminus RPN7 PF10602.9 RJW68672.1 - 0.17 11.6 6.4 12 5.6 6.2 2.6 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Pterin_4a PF01329.19 RJW68672.1 - 0.23 11.6 1.5 0.75 10.0 0.7 2.4 2 1 0 2 2 1 0 Pterin 4 alpha carbinolamine dehydratase TPR_11 PF13414.6 RJW68672.1 - 0.78 9.5 8.4 6.3 6.6 0.4 4.8 5 2 0 5 5 5 0 TPR repeat FRB_dom PF08771.11 RJW68672.1 - 1.3 9.4 6.1 0.81 10.1 0.8 2.8 2 1 0 3 3 3 0 FKBP12-rapamycin binding domain TPR_6 PF13174.6 RJW68672.1 - 1.4 9.7 9.7 11 6.8 0.1 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat Pkinase PF00069.25 RJW68673.1 - 3.3e-52 177.4 0.0 1.8e-48 165.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68673.1 - 9.2e-37 126.7 0.0 2e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW68673.1 - 9e-05 21.4 0.2 0.00047 19.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RJW68673.1 - 0.001 18.5 0.0 0.091 12.1 0.0 2.5 2 0 0 2 2 2 2 Kinase-like 6PGD PF00393.19 RJW68674.1 - 8e-124 412.7 0.0 1.1e-123 412.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 RJW68674.1 - 7.3e-50 169.2 0.0 1.2e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 RJW68674.1 - 0.00014 21.9 0.1 0.00033 20.7 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 RJW68674.1 - 0.018 15.3 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 RJW68674.1 - 0.086 13.4 0.2 0.17 12.5 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Con-6 PF10346.9 RJW68675.1 - 0.32 11.0 2.5 2 8.5 0.1 3.4 3 0 0 3 3 3 0 Conidiation protein 6 Cpn60_TCP1 PF00118.24 RJW68676.1 - 4.3e-73 246.6 10.7 9.9e-42 143.2 6.4 2.4 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family PDZ PF00595.24 RJW68677.1 - 1.1e-55 186.0 0.0 1.5e-12 47.7 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 RJW68677.1 - 8.1e-23 80.0 5.9 1.6e-05 24.7 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 RJW68677.1 - 5.3e-17 61.9 0.2 1.3e-05 25.5 0.0 4.4 4 0 0 4 4 4 3 PDZ domain zf-RING_UBOX PF13445.6 RJW68677.1 - 7.1e-06 25.9 9.3 7.1e-06 25.9 9.3 2.1 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RJW68677.1 - 6.5e-05 22.7 6.5 6.5e-05 22.7 6.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW68677.1 - 8.2e-05 22.4 5.9 8.2e-05 22.4 5.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW68677.1 - 0.00033 20.4 11.4 0.00033 20.4 11.4 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Tricorn_PDZ PF14685.6 RJW68677.1 - 0.00047 20.1 0.4 2.9 7.9 0.0 4.2 4 0 0 4 4 4 1 Tricorn protease PDZ domain zf-RING_5 PF14634.6 RJW68677.1 - 0.0014 18.5 8.5 0.0014 18.5 8.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 RJW68677.1 - 0.0031 17.8 8.7 0.0031 17.8 8.7 2.9 3 0 0 3 3 3 1 Ring finger domain zf-TRAF PF02176.18 RJW68677.1 - 0.013 16.1 0.3 0.055 14.2 0.3 2.1 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C3HC4_4 PF15227.6 RJW68677.1 - 0.017 15.3 6.9 0.046 13.9 6.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 RJW68677.1 - 0.024 14.8 7.2 0.067 13.3 7.2 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 RJW68677.1 - 0.13 12.6 8.1 0.43 10.9 8.1 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RJW68677.1 - 0.99 9.5 3.9 2.8 8.0 3.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FGGY_N PF00370.21 RJW68678.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain O-FucT PF10250.9 RJW68679.1 - 8.8e-08 32.2 0.0 2.1e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NodZ PF05830.11 RJW68679.1 - 0.0096 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) APG6 PF04111.12 RJW68680.1 - 6.1e-59 199.0 0.0 1e-58 198.2 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain G-patch PF01585.23 RJW68680.1 - 1.6e-13 50.3 4.5 3.3e-13 49.3 4.5 1.5 1 0 0 1 1 1 1 G-patch domain APG6_N PF17675.1 RJW68680.1 - 3.1e-13 50.4 25.1 3.1e-13 50.4 25.1 3.5 2 2 1 3 3 1 1 Apg6 coiled-coil region G-patch_2 PF12656.7 RJW68680.1 - 0.00019 21.5 1.2 0.00031 20.8 0.2 1.9 2 0 0 2 2 2 1 G-patch domain ATG16 PF08614.11 RJW68680.1 - 0.0028 17.9 9.2 0.0028 17.9 9.2 2.2 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) Vps5 PF09325.10 RJW68680.1 - 0.0078 15.8 1.1 0.017 14.7 1.1 1.5 1 0 0 1 1 1 1 Vps5 C terminal like BH3 PF15285.6 RJW68680.1 - 0.0096 15.7 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting IFT57 PF10498.9 RJW68680.1 - 0.016 14.2 2.3 0.043 12.8 2.3 1.6 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 RJW68680.1 - 0.086 11.7 7.9 0.063 12.2 3.8 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 RJW68680.1 - 0.2 11.9 6.6 1.5 9.2 6.6 2.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Snapin_Pallidin PF14712.6 RJW68680.1 - 0.34 11.4 5.2 0.99 9.9 5.2 1.8 1 0 0 1 1 1 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 RJW68680.1 - 0.63 9.5 3.6 0.26 10.8 0.1 2.0 3 0 0 3 3 3 0 Exonuclease VII, large subunit DivIC PF04977.15 RJW68680.1 - 1.1 9.0 9.1 0.2 11.5 1.3 2.6 1 1 1 2 2 2 0 Septum formation initiator Fez1 PF06818.15 RJW68680.1 - 1.8 9.0 14.6 0.7 10.3 6.0 3.2 2 1 1 3 3 3 0 Fez1 DUF713 PF05218.14 RJW68680.1 - 1.9 8.2 6.4 4.2 7.1 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF713) CENP-H PF05837.12 RJW68680.1 - 3.1 8.3 15.5 0.051 14.0 6.4 2.6 3 0 0 3 3 2 0 Centromere protein H (CENP-H) I_LWEQ PF01608.17 RJW68680.1 - 5.1 7.3 13.4 0.21 11.8 4.4 2.4 2 0 0 2 2 2 0 I/LWEQ domain YabA PF06156.13 RJW68680.1 - 8 7.2 7.0 2 9.1 2.0 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Aldedh PF00171.22 RJW68682.1 - 1.4e-177 590.9 0.1 1.6e-177 590.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BMC PF00936.19 RJW68682.1 - 0.012 15.6 1.0 0.27 11.3 0.0 2.7 2 0 0 2 2 2 0 BMC domain Lantibiotic_a PF14867.6 RJW68682.1 - 0.093 12.5 0.3 0.27 11.0 0.3 1.8 1 0 0 1 1 1 0 Lantibiotic alpha G-alpha PF00503.20 RJW68685.1 - 1e-116 390.0 3.2 1.3e-116 389.7 3.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RJW68685.1 - 3.5e-16 59.2 0.2 1.6e-11 44.0 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 RJW68685.1 - 0.00047 20.4 0.1 0.25 11.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 RJW68685.1 - 0.0038 17.2 0.2 0.0091 15.9 0.2 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain DAP3 PF10236.9 RJW68685.1 - 0.012 14.8 0.5 0.022 13.9 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ras PF00071.22 RJW68685.1 - 0.1 12.2 0.8 7.1 6.2 0.0 2.6 2 1 0 2 2 2 0 Ras family zf-C2H2 PF00096.26 RJW68686.1 - 8.6e-05 22.8 17.0 0.0087 16.5 0.5 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW68686.1 - 0.0025 18.5 22.3 0.054 14.4 0.7 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW68686.1 - 0.0082 16.5 2.4 0.0082 16.5 2.4 4.2 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_3rep PF18868.1 RJW68686.1 - 0.049 14.3 1.4 6.7 7.4 1.2 2.9 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats NUDIX_5 PF16705.5 RJW68686.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT EGF_3 PF12947.7 RJW68686.1 - 0.094 12.9 1.9 0.26 11.5 1.9 1.8 1 0 0 1 1 1 0 EGF domain zf-C2H2_6 PF13912.6 RJW68686.1 - 0.13 12.3 14.8 4 7.5 0.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RJW68686.1 - 0.43 10.3 16.0 1.8 8.3 0.1 3.9 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 RJW68686.1 - 1.3 8.9 11.2 0.96 9.3 0.5 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type Peptidase_C2 PF00648.21 RJW68687.1 - 3.4e-128 426.8 0.0 4.2e-128 426.5 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease SNF PF00209.18 RJW68690.1 - 7.8e-08 31.5 8.3 7.8e-08 31.5 8.3 1.8 2 0 0 2 2 2 1 Sodium:neurotransmitter symporter family AC_N PF16214.5 RJW68690.1 - 0.13 11.4 11.7 0.21 10.7 11.7 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF3112 PF11309.8 RJW68690.1 - 0.83 9.1 8.0 0.17 11.3 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) DUF4231 PF14015.6 RJW68690.1 - 1 9.8 3.3 13 6.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) GIY-YIG PF01541.24 RJW68691.1 - 0.0031 17.8 0.2 0.0057 16.9 0.2 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Cofac_haem_bdg PF04187.13 RJW68691.1 - 0.14 12.1 0.0 1.5 8.8 0.0 2.0 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN RVT_1 PF00078.27 RJW68692.1 - 2.9e-10 40.1 0.0 4.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-set PF07686.17 RJW68693.1 - 7e-06 26.2 0.5 0.2 11.9 0.0 4.5 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.6 RJW68693.1 - 0.073 13.7 0.1 22 5.7 0.0 3.8 3 0 0 3 3 3 0 Immunoglobulin domain Tudor_4 PF18358.1 RJW68693.1 - 0.083 12.5 0.0 0.27 10.8 0.0 1.9 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain RVT_1 PF00078.27 RJW68694.1 - 1.5e-11 44.2 0.0 2.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 RJW68697.1 - 3.6e-27 95.4 0.1 1.6e-18 67.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68697.1 - 0.0096 15.2 0.1 2.4 7.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Vir_act_alpha_C PF10400.9 RJW68697.1 - 0.14 12.8 5.8 0.34 11.6 0.0 2.4 2 0 0 2 2 2 0 Virulence activator alpha C-term Pox_ser-thr_kin PF05445.11 RJW68697.1 - 0.17 10.8 0.0 0.53 9.2 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF1043 PF06295.12 RJW68698.1 - 0.00093 19.2 7.9 0.86 9.6 2.9 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF1043) SecIII_SopE_N PF05364.14 RJW68698.1 - 0.025 14.6 0.1 0.078 13.1 0.1 1.8 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus BAR_3_WASP_bdg PF10456.9 RJW68698.1 - 0.35 10.3 2.5 1.1 8.7 0.7 2.1 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein DUF4239 PF14023.6 RJW68698.1 - 1.9 8.2 8.3 2.1 8.0 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF3450 PF11932.8 RJW68698.1 - 4.9 6.4 18.0 1.9 7.7 6.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) dCache_3 PF14827.6 RJW68698.1 - 5.7 6.5 10.9 9 5.9 2.3 2.7 3 0 0 3 3 3 0 Double sensory domain of two-component sensor kinase Amino_oxidase PF01593.24 RJW68700.1 - 1.5e-36 126.7 0.0 4e-25 89.0 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RJW68700.1 - 2.9e-10 40.2 0.1 1.1e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RJW68700.1 - 2.7e-06 27.2 2.5 5.4e-06 26.2 2.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 RJW68700.1 - 1.5e-05 24.4 0.3 2.4e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 RJW68700.1 - 4.7e-05 22.8 0.0 7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RJW68700.1 - 8.6e-05 21.8 0.9 0.00014 21.1 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 RJW68700.1 - 0.00033 20.1 0.6 0.0057 16.1 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RJW68700.1 - 0.00078 18.2 0.2 0.0011 17.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 RJW68700.1 - 0.0027 18.2 0.2 0.023 15.2 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RJW68700.1 - 0.0031 16.8 0.6 0.0064 15.8 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 RJW68700.1 - 0.022 14.1 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 RJW68700.1 - 0.055 12.5 0.3 0.082 11.9 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 RJW68700.1 - 0.093 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 RJW68700.1 - 0.12 11.4 0.2 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 RJW68700.1 - 0.34 10.1 0.9 0.51 9.5 0.9 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_8 PF01501.20 RJW68701.1 - 3e-09 36.8 0.0 4.1e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 ASC PF00858.24 RJW68702.1 - 4.1e-59 200.7 2.0 7.7e-59 199.8 2.0 1.4 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel OATP PF03137.20 RJW68703.1 - 2.1e-141 471.9 13.7 2.8e-141 471.5 13.7 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family RVT_1 PF00078.27 RJW68703.1 - 3.4e-38 131.4 0.0 6e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 RJW68703.1 - 3e-13 49.4 33.0 1.1e-11 44.3 6.4 3.3 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 RJW68703.1 - 0.042 14.0 9.3 0.11 12.7 8.2 2.4 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain zf-CW PF07496.15 RJW68704.1 - 0.012 15.6 0.6 1 9.5 0.1 2.2 2 0 0 2 2 2 0 CW-type Zinc Finger Glyco_transf_8 PF01501.20 RJW68705.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 RJW68705.1 - 0.031 13.7 0.1 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 Glucosyltransferase 24 Homeodomain PF00046.29 RJW68706.1 - 4.4e-16 58.5 1.9 5.9e-16 58.1 1.0 1.7 2 0 0 2 2 2 1 Homeodomain LIM PF00412.22 RJW68706.1 - 3e-13 49.8 25.9 4.9e-09 36.3 10.4 2.6 2 0 0 2 2 2 2 LIM domain DBP PF12361.8 RJW68706.1 - 0.061 13.2 1.8 0.11 12.3 1.8 1.4 1 0 0 1 1 1 0 Duffy-antigen binding protein Homeobox_KN PF05920.11 RJW68706.1 - 0.1 12.5 0.3 0.3 11.0 0.3 1.8 1 0 0 1 1 1 0 Homeobox KN domain Dynein_light PF01221.18 RJW68707.1 - 5.4e-35 119.6 0.0 6e-35 119.4 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 RJW68707.1 - 0.066 12.7 0.0 0.071 12.6 0.0 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin DUF3695 PF12494.8 RJW68708.1 - 2.9e-10 39.9 0.0 4.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) Guanylate_kin PF00625.21 RJW68709.1 - 3.5e-43 147.4 0.4 5.1e-43 146.9 0.4 1.2 1 0 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.28 RJW68709.1 - 0.00096 18.7 0.2 0.0032 17.0 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 RJW68709.1 - 0.16 11.7 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain Nop14 PF04147.12 RJW68709.1 - 0.87 7.7 19.0 1.3 7.2 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RJW68709.1 - 2.9 7.2 20.3 4.7 6.5 20.3 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 RJW68709.1 - 3.9 5.4 26.7 5.9 4.9 26.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Dynein_light PF01221.18 RJW68711.1 - 4.1e-44 148.8 2.2 4.5e-44 148.7 2.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.29 RJW68711.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ectatomin PF06457.11 RJW68711.1 - 0.17 11.8 0.3 0.3 11.0 0.3 1.3 1 0 0 1 1 1 0 Ectatomin Ig_3 PF13927.6 RJW68718.1 - 1.2e-26 93.1 0.3 6.3e-14 52.3 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RJW68718.1 - 2.6e-24 85.1 0.0 1.4e-12 47.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain V-set PF07686.17 RJW68718.1 - 3e-22 78.9 1.1 4e-09 36.6 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.6 RJW68718.1 - 3.1e-17 62.7 0.4 5e-10 39.6 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RJW68718.1 - 3.8e-17 62.2 1.4 4.5e-05 23.5 0.0 4.2 4 2 0 4 4 4 3 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 RJW68718.1 - 4.4e-08 32.8 1.6 2.8e-06 27.0 0.0 2.7 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 RJW68718.1 - 3.3e-06 26.5 0.0 1.3 8.6 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Izumo-Ig PF16706.5 RJW68718.1 - 0.023 14.8 0.8 16 5.7 0.0 3.7 3 1 0 3 3 3 0 Izumo-like Immunoglobulin domain Dynein_light PF01221.18 RJW68719.1 - 8.5e-31 106.1 1.4 1e-30 105.9 1.4 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3388 PF11868.8 RJW68719.1 - 0.051 12.9 0.1 0.061 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) DDR PF08841.10 RJW68719.1 - 0.14 11.1 1.2 0.17 10.9 1.2 1.0 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Zip PF02535.22 RJW68720.1 - 3.5e-40 138.2 15.9 3.1e-27 95.7 0.1 3.3 3 1 0 3 3 3 2 ZIP Zinc transporter DUF21 PF01595.20 RJW68720.1 - 0.11 12.2 1.9 0.4 10.4 1.8 2.1 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain MpPF26 PF07666.11 RJW68720.1 - 0.12 12.5 1.3 0.65 10.1 0.1 2.6 2 0 0 2 2 2 0 M penetrans paralogue family 26 Dynein_light PF01221.18 RJW68721.1 - 4.7e-24 84.5 0.0 7.2e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Smg8_Smg9 PF10220.9 RJW68723.1 - 2.1e-107 360.5 0.0 9.7e-70 236.0 0.0 4.1 3 1 0 3 3 3 3 Smg8_Smg9 TBCC PF07986.12 RJW68724.1 - 3.5e-38 130.0 4.6 5.5e-38 129.4 3.4 2.0 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 RJW68724.1 - 0.069 12.8 1.5 0.075 12.7 0.4 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal Spt4 PF06093.13 RJW68724.1 - 0.8 9.8 8.9 2.6 8.2 4.1 3.7 5 0 0 5 5 5 0 Spt4/RpoE2 zinc finger tRNA_anti-codon PF01336.25 RJW68725.1 - 1.6e-07 31.2 0.2 3.4e-06 26.9 0.2 2.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain HA2 PF04408.23 RJW68726.1 - 1.1e-14 54.6 0.0 3.6e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RJW68726.1 - 1.8e-11 44.4 0.0 3.7e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RJW68726.1 - 0.00025 20.9 0.2 0.0013 18.6 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RJW68726.1 - 0.0037 17.6 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 RJW68726.1 - 0.0074 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ATPase PF06745.13 RJW68726.1 - 0.17 11.2 0.0 0.38 10.1 0.0 1.5 1 0 0 1 1 1 0 KaiC PAP_central PF04928.17 RJW68727.1 - 6.4e-34 117.1 0.6 4.4e-23 81.6 0.0 2.6 3 0 0 3 3 3 2 Poly(A) polymerase central domain RVT_1 PF00078.27 RJW68727.1 - 0.00011 21.8 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rhodanese PF00581.20 RJW68728.1 - 4.6e-12 46.4 0.0 8.7e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain Cadherin PF00028.17 RJW68730.1 - 3.7e-24 85.0 0.2 4.1e-09 36.8 0.0 3.7 3 0 0 3 3 3 3 Cadherin domain TLP1_add_C PF18313.1 RJW68730.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain Sugar_tr PF00083.24 RJW68731.1 - 1.8e-97 327.1 22.8 2.1e-97 326.8 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW68731.1 - 6.3e-25 87.8 22.2 6.3e-25 87.8 22.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 RJW68731.1 - 0.02 15.4 1.3 0.02 15.4 1.3 2.6 2 1 1 3 3 3 0 Phage holin family 2 SNF2_N PF00176.23 RJW68732.1 - 1.4e-26 93.1 0.0 2.2e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HARP PF07443.13 RJW68732.1 - 4.5e-17 61.4 0.0 9.5e-17 60.4 0.0 1.6 1 0 0 1 1 1 1 HepA-related protein (HARP) Helicase_C PF00271.31 RJW68732.1 - 6.2e-14 52.3 0.0 1.9e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW68732.1 - 4.7e-05 23.5 0.0 9.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 RJW68732.1 - 0.026 14.5 0.0 0.089 12.8 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 RJW68732.1 - 0.1 12.0 0.2 0.69 9.3 0.0 2.3 3 0 0 3 3 3 0 Bacterial TniB protein Sugar_tr PF00083.24 RJW68735.1 - 1.3e-85 288.0 10.5 1.5e-85 287.8 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW68735.1 - 5.3e-16 58.5 11.2 7.3e-16 58.0 11.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SEP PF08059.13 RJW68738.1 - 5.8e-14 52.4 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 SEP domain DUF627 PF04781.12 RJW68738.1 - 0.058 13.4 0.1 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF627) DUF1299 PF06975.11 RJW68740.1 - 0.13 12.3 0.2 4.9 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) Glyco_transf_41 PF13844.6 RJW68741.1 - 9e-251 832.2 0.0 1.2e-250 831.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 RJW68741.1 - 2.7e-91 296.0 31.9 2.3e-08 33.5 0.3 13.2 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.6 RJW68741.1 - 4.9e-87 285.4 31.4 4e-11 42.4 1.2 13.1 3 2 10 13 13 13 12 TPR repeat TPR_2 PF07719.17 RJW68741.1 - 3.9e-70 226.4 28.9 2.1e-06 27.4 0.2 12.7 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 RJW68741.1 - 1.1e-63 207.1 39.6 4.2e-07 29.9 0.1 13.5 14 0 0 14 14 13 12 Tetratricopeptide repeat TPR_8 PF13181.6 RJW68741.1 - 2.4e-61 198.9 21.3 2.6e-05 24.1 0.0 13.0 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 RJW68741.1 - 2.4e-44 149.5 29.9 4.5e-11 42.9 2.1 9.5 6 2 3 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 RJW68741.1 - 1.8e-43 143.5 13.0 0.00074 20.1 0.0 12.0 5 3 7 12 12 12 10 Tetratricopeptide repeat TPR_16 PF13432.6 RJW68741.1 - 4.6e-43 145.6 15.2 1e-07 32.5 0.7 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 RJW68741.1 - 6e-38 126.1 18.4 0.0005 19.9 0.1 13.3 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_19 PF14559.6 RJW68741.1 - 2.4e-35 120.9 25.8 5e-06 26.9 0.1 9.6 4 2 7 11 11 10 10 Tetratricopeptide repeat TPR_10 PF13374.6 RJW68741.1 - 7.5e-35 117.8 44.2 6e-06 26.0 1.4 12.0 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_9 PF13371.6 RJW68741.1 - 1.2e-15 57.4 8.2 0.047 13.8 0.1 6.5 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 RJW68741.1 - 2.9e-14 52.7 20.5 0.079 13.6 0.1 10.8 11 0 0 11 11 11 3 Tetratricopeptide repeat NARP1 PF12569.8 RJW68741.1 - 1.9e-12 46.9 6.7 0.0059 15.6 0.1 5.5 1 1 5 6 6 6 3 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 RJW68741.1 - 2e-09 37.3 8.3 0.012 15.0 2.1 5.1 1 1 2 4 4 4 3 MalT-like TPR region TPR_4 PF07721.14 RJW68741.1 - 1.1e-07 31.8 6.5 4 8.4 0.2 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat FAT PF02259.23 RJW68741.1 - 2.2e-07 30.4 0.4 0.57 9.3 0.0 5.2 2 2 2 4 4 4 2 FAT domain EST1_DNA_bind PF10373.9 RJW68741.1 - 5.7e-07 29.3 12.2 0.018 14.5 0.2 4.4 4 0 0 4 4 4 3 Est1 DNA/RNA binding domain Wzy_C_2 PF11846.8 RJW68741.1 - 0.00011 22.2 5.1 0.035 14.0 0.6 3.9 2 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal TPR_15 PF13429.6 RJW68741.1 - 0.00011 21.5 14.4 0.0025 17.1 4.4 4.5 1 1 1 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 RJW68741.1 - 0.00026 20.4 5.3 0.14 11.6 0.0 5.3 5 2 2 7 7 6 1 SHNi-TPR TPR_21 PF09976.9 RJW68741.1 - 0.0012 18.6 14.1 2.9 7.5 0.1 5.7 3 2 2 5 5 5 1 Tetratricopeptide repeat-like domain MIT PF04212.18 RJW68741.1 - 0.0018 18.3 25.5 9.9 6.3 0.2 9.2 9 1 1 10 10 9 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 RJW68741.1 - 0.0083 15.6 16.3 0.79 9.1 0.2 4.9 1 1 3 4 4 4 2 Soluble NSF attachment protein, SNAP T2SSF PF00482.23 RJW68741.1 - 0.015 15.2 0.1 2.6 8.0 0.1 3.4 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Fis1_TPR_C PF14853.6 RJW68741.1 - 0.016 15.3 1.7 0.12 12.4 0.1 3.4 4 0 0 4 4 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 RJW68741.1 - 0.017 15.1 9.0 13 5.9 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 RJW68741.1 - 0.019 15.3 12.0 1.2 9.6 0.1 6.1 4 1 1 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.17 RJW68741.1 - 0.023 15.1 17.0 0.84 10.1 2.1 5.4 2 2 1 5 5 5 0 Bacterial transcriptional activator domain TOM20_plant PF06552.12 RJW68741.1 - 0.029 14.1 2.0 33 4.2 0.0 4.9 3 1 2 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 DUF3896 PF13035.6 RJW68741.1 - 0.065 13.4 0.0 0.24 11.6 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) RPN7 PF10602.9 RJW68741.1 - 0.098 12.4 7.9 0.76 9.5 0.1 5.2 2 2 4 6 6 6 0 26S proteasome subunit RPN7 PPR PF01535.20 RJW68741.1 - 0.65 10.4 5.2 42 4.7 0.0 5.8 7 0 0 7 7 6 0 PPR repeat ANAPC3 PF12895.7 RJW68741.1 - 1 9.6 24.3 0.041 14.1 1.4 5.9 2 2 7 9 9 9 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 RJW68741.1 - 1.7 9.1 8.2 1.4 9.4 0.1 3.7 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation Mad3_BUB1_I PF08311.12 RJW68741.1 - 5.5 7.0 9.2 58 3.7 0.1 5.5 6 1 1 7 7 7 0 Mad3/BUB1 homology region 1 Cyclin_N PF00134.23 RJW68744.1 - 7e-25 87.2 0.1 2e-24 85.8 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RJW68744.1 - 1.9e-08 34.4 1.2 1.2e-05 25.4 0.2 2.9 3 0 0 3 3 3 2 Cyclin, C-terminal domain JAB PF01398.21 RJW68745.1 - 2.3e-32 111.4 0.0 3.9e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RJW68745.1 - 5e-14 52.7 0.1 8.5e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 RJW68745.1 - 7.9e-06 25.6 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Nbas_N PF15492.6 RJW68750.1 - 0.065 12.5 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal FANCI_S2 PF14676.6 RJW68751.1 - 1.5e-18 67.7 0.6 4.4e-18 66.1 0.0 2.2 2 0 0 2 2 2 1 FANCI solenoid 2 FANCI_HD2 PF14680.6 RJW68751.1 - 2.8e-07 30.1 0.6 0.0025 17.1 0.2 3.5 3 1 0 3 3 3 2 FANCI helical domain 2 FANCI_HD1 PF14679.6 RJW68751.1 - 5.1e-07 29.6 0.1 2.8e-06 27.2 0.0 2.4 3 0 0 3 3 3 1 FANCI helical domain 1 FANCI_S1 PF14675.6 RJW68751.1 - 0.013 15.1 1.1 0.031 13.8 1.1 1.6 1 0 0 1 1 1 0 FANCI solenoid 1 PIH1_CS PF18201.1 RJW68752.1 - 1.5e-09 38.1 0.1 2.5e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 RJW68752.1 - 0.0066 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA KTSC PF13619.6 RJW68752.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 KTSC domain RVT_1 PF00078.27 RJW68756.1 - 8.1e-34 117.1 0.0 1.4e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_5 PF13873.6 RJW68756.1 - 0.0033 17.5 0.3 0.0064 16.5 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain p450 PF00067.22 RJW68756.1 - 0.012 14.4 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 Myb_DNA-bind_4 PF13837.6 RJW68756.1 - 0.073 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF1676 PF07898.13 RJW68757.1 - 0.029 14.4 4.2 6.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) CSN8_PSD8_EIF3K PF10075.9 RJW68758.1 - 4.8e-29 101.2 0.7 7.6e-29 100.5 0.7 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DED PF01335.21 RJW68759.1 - 0.00063 20.0 0.1 0.0031 17.8 0.0 2.1 2 0 0 2 2 2 1 Death effector domain NCD2 PF04905.13 RJW68761.1 - 3.1e-10 40.1 0.1 6.2e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) WD40 PF00400.32 RJW68761.1 - 1.3e-06 29.0 0.0 0.53 11.3 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat LRR_8 PF13855.6 RJW68761.1 - 3e-05 23.7 0.2 9.7e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 RJW68761.1 - 0.011 16.1 0.9 0.072 13.5 0.9 2.3 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) DoxX_2 PF13564.6 RJW68762.1 - 0.13 12.4 3.1 0.2 11.8 2.5 1.7 1 1 0 1 1 1 0 DoxX-like family ABC2_membrane_3 PF12698.7 RJW68762.1 - 0.19 10.8 3.9 0.25 10.4 3.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3533 PF12051.8 RJW68762.1 - 2.8 6.8 8.0 3.2 6.6 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF3341 PF11821.8 RJW68762.1 - 3.6 7.2 6.1 1.3 8.7 2.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) Apq12 PF12716.7 RJW68762.1 - 5.8 7.0 13.3 0.82 9.7 8.5 2.1 2 1 0 2 2 2 0 Nuclear pore assembly and biogenesis YccF PF03733.13 RJW68762.1 - 9.5 7.0 12.3 11 6.8 0.9 3.0 3 0 0 3 3 3 0 Inner membrane component domain AAA PF00004.29 RJW68765.1 - 1.3e-11 45.0 0.0 3.5e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RJW68765.1 - 6.7e-05 23.2 0.2 0.0012 19.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 RJW68765.1 - 7.9e-05 22.7 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RJW68765.1 - 0.00023 21.4 0.1 0.0017 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RJW68765.1 - 0.00029 21.3 0.0 0.017 15.5 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RJW68765.1 - 0.00036 20.3 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RJW68765.1 - 0.00062 20.0 0.0 0.0033 17.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RJW68765.1 - 0.0011 19.5 0.0 0.0025 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RJW68765.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 RJW68765.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 KaiC Rad17 PF03215.15 RJW68765.1 - 0.035 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 RJW68765.1 - 0.047 13.0 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 RJW68765.1 - 0.047 14.1 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RJW68765.1 - 0.055 13.0 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RJW68765.1 - 0.074 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_8 PF12780.7 RJW68765.1 - 0.08 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_assoc_2 PF16193.5 RJW68765.1 - 0.082 13.2 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA C-terminal domain DnaB_C PF03796.15 RJW68765.1 - 0.087 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_30 PF13604.6 RJW68765.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1871 PF08958.10 RJW68765.1 - 0.18 12.2 0.0 4.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1871) DNA_pol3_delta PF06144.13 RJW68765.1 - 0.22 11.3 0.1 0.39 10.5 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Rcd1 PF04078.13 RJW68768.1 - 4.8e-30 104.7 0.3 1.7e-28 99.6 0.3 2.7 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like RBD-FIP PF09457.10 RJW68768.1 - 0.18 11.7 1.7 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 FIP domain SAB PF04382.13 RJW68769.1 - 0.023 14.8 0.2 10 6.3 0.0 2.4 2 0 0 2 2 2 0 SAB domain DUF2271 PF10029.9 RJW68769.1 - 0.17 11.5 0.8 0.77 9.4 0.8 2.1 1 1 0 1 1 1 0 Predicted periplasmic protein (DUF2271) WD40 PF00400.32 RJW68770.1 - 1.5e-23 82.6 7.5 4.2e-05 24.2 0.1 8.0 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW68770.1 - 6.9e-05 23.1 0.0 5.4 7.4 0.0 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW68770.1 - 0.015 14.3 0.0 0.59 9.0 0.1 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Myb_DNA-bind_5 PF13873.6 RJW68771.1 - 0.00024 21.1 0.1 0.00024 21.1 0.1 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RJW68771.1 - 0.023 15.1 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TRAM_LAG1_CLN8 PF03798.16 RJW68772.1 - 4.5e-26 91.8 15.7 5.2e-26 91.6 15.7 1.0 1 0 0 1 1 1 1 TLC domain DHHC PF01529.20 RJW68777.1 - 2.9e-34 118.0 16.2 4.9e-34 117.3 16.2 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase RVT_1 PF00078.27 RJW68779.1 - 1.2e-08 34.7 0.1 4.9e-08 32.8 0.0 1.8 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3509 PF12021.8 RJW68780.1 - 0.0043 16.8 0.0 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) DEAD PF00270.29 RJW68781.1 - 7.8e-32 110.4 0.0 2.2e-31 109.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW68781.1 - 2.1e-23 82.8 0.0 4.5e-22 78.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 RJW68781.1 - 0.0007 19.0 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 RJW68781.1 - 0.0024 17.9 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Plexin_cytopl PF08337.12 RJW68782.1 - 2.2e-127 426.1 1.3 3.9e-69 233.8 0.0 2.2 2 0 0 2 2 2 2 Plexin cytoplasmic RasGAP domain PSI PF01437.25 RJW68782.1 - 4.3e-15 56.0 37.9 1.3e-07 32.0 7.1 4.1 3 0 0 3 3 3 3 Plexin repeat TIG PF01833.24 RJW68782.1 - 4.3e-12 45.9 1.5 0.00029 20.9 0.0 5.0 4 0 0 4 4 4 2 IPT/TIG domain Sema PF01403.19 RJW68782.1 - 8.8e-06 24.8 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Sema domain FF PF01846.19 RJW68783.1 - 1.5e-38 130.7 13.7 6.9e-09 35.7 0.6 6.6 6 0 0 6 6 6 5 FF domain WW PF00397.26 RJW68783.1 - 2e-19 69.4 11.7 4.4e-09 36.3 5.0 2.8 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 RJW68783.1 - 0.0025 18.5 6.3 0.076 13.7 0.0 4.6 3 1 1 4 4 4 1 p190-A and -B Rho GAPs FF domain Clat_adaptor_s PF01217.20 RJW68783.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Glyco_hyd_101C PF17451.2 RJW68783.1 - 0.1 12.9 5.9 2.9 8.2 1.3 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain IQ PF00612.27 RJW68784.1 - 0.021 14.6 1.5 0.061 13.1 1.5 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF608 PF04685.13 RJW68787.1 - 8.6e-135 449.5 0.7 1.1e-134 449.2 0.7 1.1 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 RJW68787.1 - 2.5e-81 273.6 0.0 3.7e-81 273.0 0.0 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term CEP19 PF14933.6 RJW68790.1 - 5e-30 105.0 2.4 1.4e-29 103.5 2.4 1.6 1 1 0 1 1 1 1 CEP19-like protein PMC2NT PF08066.12 RJW68790.1 - 0.032 14.9 1.6 0.11 13.3 0.7 2.0 1 1 1 2 2 2 0 PMC2NT (NUC016) domain RTTN_N PF14726.6 RJW68790.1 - 0.047 14.5 0.5 0.096 13.5 0.3 1.6 1 1 1 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning DUF5312 PF17239.2 RJW68790.1 - 0.053 11.9 0.1 0.064 11.6 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5312) cNMP_binding PF00027.29 RJW68791.1 - 5.9e-41 138.5 0.0 1.1e-14 54.2 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 RJW68791.1 - 1.3e-20 74.5 0.0 4.1e-20 72.8 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase DUF1908 PF08926.11 RJW68794.1 - 0.1 11.6 2.2 0.093 11.8 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) Acyl-CoA_dh_1 PF00441.24 RJW68795.1 - 1e-41 142.7 6.9 3e-39 134.6 4.2 2.2 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RJW68795.1 - 1.6e-27 95.6 0.1 3.1e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RJW68795.1 - 1.9e-15 57.3 6.5 1e-14 54.9 3.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RJW68795.1 - 0.0015 19.1 0.0 0.0085 16.7 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain ASTN_2_hairpin PF18577.1 RJW68796.1 - 0.039 14.1 0.4 1.2 9.4 0.4 2.6 2 0 0 2 2 2 0 Astrotactin-2 C-terminal beta-hairpin domain PseudoU_synth_1 PF01416.20 RJW68797.1 - 6.2e-30 103.8 0.0 1.6e-27 96.1 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase RPN1_RPN2_N PF17781.1 RJW68798.1 - 2.9e-113 378.4 0.5 5.3e-113 377.5 0.5 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 RJW68798.1 - 3e-29 100.8 0.1 6.9e-29 99.7 0.1 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 RJW68798.1 - 9.3e-16 57.4 18.9 0.00029 21.1 0.1 9.3 9 0 0 9 9 9 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 RJW68798.1 - 0.15 12.5 1.3 14 6.2 0.0 3.3 4 0 0 4 4 4 0 HEAT repeats Presenilin PF01080.17 RJW68798.1 - 0.18 10.5 2.1 0.31 9.8 2.1 1.3 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.12 RJW68798.1 - 3.3 7.0 8.9 7 5.9 8.9 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger MVP_shoulder PF11978.8 RJW68799.1 - 1.5e-54 183.0 0.3 2.9e-54 182.1 0.3 1.5 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.18 RJW68799.1 - 8.5e-53 176.3 1.1 3.2e-15 56.0 0.0 4.9 5 0 0 5 5 5 4 Major Vault Protein repeat domain Vault_3 PF17795.1 RJW68799.1 - 5.8e-34 115.9 0.1 5.7e-33 112.8 0.0 2.6 3 0 0 3 3 3 1 Major Vault Protein Repeat domain Vault_2 PF17794.1 RJW68799.1 - 3.4e-33 113.8 0.2 6.8e-22 77.6 0.0 2.6 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 RJW68799.1 - 1e-30 105.6 0.1 4.7e-29 100.3 0.0 3.4 4 0 0 4 4 4 1 Major Vault Protein repeat domain Cut12 PF11500.8 RJW68799.1 - 0.0073 16.3 1.4 0.0073 16.3 1.4 2.1 2 0 0 2 2 2 1 Spindle pole body formation-associated protein DUF2543 PF10820.8 RJW68799.1 - 2.9 8.1 4.8 0.64 10.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) Mtp PF03821.16 RJW68803.1 - 0.014 15.0 0.7 0.02 14.5 0.7 1.2 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Nucleoside_tran PF01733.18 RJW68804.1 - 2.1e-37 129.2 7.4 2.3e-37 129.1 7.4 1.0 1 0 0 1 1 1 1 Nucleoside transporter Cation_ATPase_C PF00689.21 RJW68804.1 - 0.84 9.3 8.9 0.67 9.6 6.6 1.9 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus Yip1 PF04893.17 RJW68804.1 - 1.7 8.3 14.8 2 8.1 2.0 2.2 1 1 1 2 2 2 0 Yip1 domain tRNA-synt_2c PF01411.19 RJW68808.1 - 2.6e-82 277.1 0.0 5.4e-63 213.4 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.14 RJW68808.1 - 9.7e-05 22.4 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PARP PF00644.20 RJW68810.1 - 3.1e-43 147.6 0.0 7.4e-43 146.4 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 RJW68810.1 - 1.2e-37 129.0 0.0 2.2e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 RJW68810.1 - 1.2e-06 28.4 0.4 1.2e-06 28.4 0.4 2.4 2 0 0 2 2 2 1 WGR domain Ribosomal_L11_N PF03946.14 RJW68810.1 - 0.0076 16.1 0.3 0.81 9.6 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L11, N-terminal domain DUF773 PF05600.12 RJW68812.1 - 7.9e-67 226.1 4.9 7.3e-50 170.1 0.7 2.0 2 0 0 2 2 2 2 CDK5 regulatory subunit-associated protein 3 SurA_N_2 PF13623.6 RJW68812.1 - 0.024 14.5 1.0 0.076 12.9 0.1 2.3 2 0 0 2 2 2 0 SurA N-terminal domain Jag_N PF14804.6 RJW68812.1 - 0.099 13.0 0.5 0.28 11.6 0.5 1.7 1 0 0 1 1 1 0 Jag N-terminus YscO-like PF16789.5 RJW68812.1 - 0.97 9.4 5.5 0.63 10.1 0.9 2.3 2 0 0 2 2 2 0 YscO-like protein Mod_r PF07200.13 RJW68812.1 - 6.6 6.8 9.3 4.4 7.4 2.2 2.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ion_trans_N PF08412.10 RJW68813.1 - 4.3e-25 87.0 0.3 4.3e-25 87.0 0.3 1.9 2 0 0 2 2 2 1 Ion transport protein N-terminal CENP-R PF06729.12 RJW68813.1 - 0.5 10.3 4.7 0.19 11.7 0.4 2.3 1 1 1 2 2 2 0 Kinetochore component, CENP-R Ank_2 PF12796.7 RJW68814.1 - 4.4e-13 49.6 0.0 7.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW68814.1 - 1.5e-12 47.8 0.4 0.00026 21.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RJW68814.1 - 2.5e-10 40.3 0.9 7.2e-06 26.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RJW68814.1 - 7.1e-10 39.0 0.6 8.1e-06 26.0 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW68814.1 - 2.4e-09 36.6 0.1 0.00034 20.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat ArnB_C PF18677.1 RJW68814.1 - 0.61 10.2 7.3 0.048 13.8 1.7 2.1 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain Peptidase_M24 PF00557.24 RJW68815.1 - 1.4e-09 38.0 0.0 2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF150 PF02576.17 RJW68815.1 - 0.017 15.5 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 RimP N-terminal domain EXOSC1 PF10447.9 RJW68816.1 - 2e-09 38.0 0.0 6.3e-09 36.4 0.0 1.7 1 1 1 2 2 2 1 Exosome component EXOSC1/CSL4 DDE_1 PF03184.19 RJW68817.1 - 6.6e-07 29.2 0.0 9.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 RJW68817.1 - 2.4e-05 24.0 0.0 5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 RJW68817.1 - 4.8e-05 23.3 0.0 0.031 14.3 0.0 2.7 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain PTPLA PF04387.14 RJW68818.1 - 2e-51 174.0 5.2 3.4e-51 173.2 5.2 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CS PF04969.16 RJW68818.1 - 5e-05 24.2 0.0 0.00011 23.2 0.0 1.6 1 0 0 1 1 1 1 CS domain Actin PF00022.19 RJW68819.1 - 1.1e-46 159.3 0.0 2.2e-45 155.0 0.0 2.1 1 1 0 1 1 1 1 Actin P2X_receptor PF00864.19 RJW68820.1 - 1.1e-97 327.4 0.3 1.2e-97 327.3 0.3 1.0 1 0 0 1 1 1 1 ATP P2X receptor BrkDBD PF09607.10 RJW68820.1 - 0.016 15.0 0.2 0.03 14.1 0.2 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain HSP70 PF00012.20 RJW68821.1 - 2.9e-270 897.6 10.1 3.4e-270 897.4 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RJW68821.1 - 6.4e-16 58.1 0.9 1.6e-13 50.2 0.5 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 RJW68821.1 - 1e-05 25.9 0.2 0.2 12.1 0.0 3.8 3 1 0 3 3 3 2 Cell division protein FtsA cwf21 PF08312.12 RJW68821.1 - 0.02 15.0 1.1 0.93 9.7 0.4 2.5 2 0 0 2 2 2 0 cwf21 domain Phe_tRNA-synt_N PF02912.18 RJW68821.1 - 0.056 13.4 1.8 0.18 11.8 1.8 1.9 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain MukF_M PF17192.4 RJW68821.1 - 0.28 10.9 1.9 2.1 8.1 1.7 2.3 2 1 1 3 3 3 0 MukF middle domain YabA PF06156.13 RJW68821.1 - 0.57 10.9 3.2 0.9 10.2 2.3 1.8 2 0 0 2 2 2 0 Initiation control protein YabA Spectrin PF00435.21 RJW68821.1 - 1.4 9.5 7.3 4 8.0 7.3 1.8 1 0 0 1 1 1 0 Spectrin repeat FIVAR PF07554.13 RJW68821.1 - 9.3 7.1 7.5 93 3.9 7.5 2.7 1 1 0 1 1 1 0 FIVAR domain Mito_fiss_reg PF05308.11 RJW68822.1 - 0.21 11.6 6.7 0.22 11.6 6.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 RJW68822.1 - 0.58 9.6 11.3 0.7 9.3 11.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 RJW68822.1 - 2.2 8.4 14.7 0.33 11.0 10.8 1.6 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 MMS1_N PF10433.9 RJW68823.1 - 3e-49 168.0 0.0 7.3e-49 166.7 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 RJW68823.1 - 1.4e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 CPSF A subunit region Ion_trans_N PF08412.10 RJW68824.1 - 3e-23 81.1 0.2 6.2e-23 80.1 0.2 1.6 1 0 0 1 1 1 1 Ion transport protein N-terminal Ion_trans PF00520.31 RJW68824.1 - 1.6e-22 79.9 18.5 3.4e-22 78.9 18.5 1.5 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 RJW68824.1 - 2.9e-19 68.9 0.0 5.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RJW68824.1 - 0.00074 19.4 0.1 0.0021 18.0 0.1 1.8 1 0 0 1 1 1 1 Ion channel Amidohydro_1 PF01979.20 RJW68825.1 - 8.7e-18 64.7 0.0 3.3e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 RJW68825.1 - 2.8e-05 23.8 0.1 0.0022 17.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Glyco_transf_22 PF03901.17 RJW68826.1 - 7.5e-45 153.9 25.8 2.9e-44 151.9 25.8 1.7 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Peptidase_C48 PF02902.19 RJW68827.1 - 4.9e-13 49.4 1.4 1.1e-11 45.0 1.4 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DRMBL PF07522.14 RJW68828.1 - 2.9e-19 69.3 0.2 6.8e-19 68.1 0.2 1.6 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 RJW68828.1 - 0.0037 16.8 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 RJW68828.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain zf-C2H2 PF00096.26 RJW68829.1 - 9.3e-17 60.5 23.2 3.1e-06 27.3 3.2 4.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW68829.1 - 4.4e-14 52.2 26.1 2.6e-06 27.6 0.8 4.9 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW68829.1 - 1.4e-11 44.2 19.4 0.0013 19.4 2.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW68829.1 - 4.2e-08 33.3 3.1 0.061 13.6 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW68829.1 - 5.4e-07 29.5 14.7 0.034 14.1 0.7 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 RJW68829.1 - 0.0022 18.3 10.0 3.2 8.3 0.9 3.8 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 RJW68829.1 - 0.064 13.2 11.0 0.56 10.2 0.6 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 RJW68829.1 - 0.14 12.5 13.5 0.89 9.9 4.8 3.3 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 RJW68829.1 - 0.63 10.0 3.3 27 4.8 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zn-C2H2_12 PF18112.1 RJW68829.1 - 0.65 10.5 4.2 0.36 11.3 0.2 2.7 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain LIM PF00412.22 RJW68829.1 - 1.2 9.4 3.2 16 5.8 4.1 2.2 1 1 1 2 2 2 0 LIM domain zf_UBZ PF18439.1 RJW68829.1 - 1.3 8.6 8.0 9.2 6.0 0.6 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Ion_trans PF00520.31 RJW68830.1 - 2.2e-24 86.0 18.4 5.5e-24 84.7 18.4 1.6 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 RJW68830.1 - 1.2e-19 70.2 0.0 2.2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RJW68830.1 - 0.0018 18.2 1.7 0.0039 17.1 0.9 2.0 1 1 0 1 1 1 1 Ion channel DUF1168 PF06658.12 RJW68831.1 - 1.3e-36 125.4 2.8 1.8e-36 125.0 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Peptidase_S49_N PF08496.10 RJW68831.1 - 0.48 10.5 6.3 0.67 10.0 6.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EMC3_TMCO1 PF01956.16 RJW68831.1 - 0.54 10.0 4.5 0.74 9.5 4.5 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RVT_1 PF00078.27 RJW68834.1 - 1.8e-14 53.8 0.0 1.3e-06 28.1 0.0 3.1 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Rbsn PF11464.8 RJW68834.1 - 0.14 11.9 2.5 13 5.6 0.2 2.7 2 0 0 2 2 2 0 Rabenosyn Rab binding domain RRP36 PF06102.12 RJW68835.1 - 4e-18 65.9 24.1 5.3e-18 65.5 24.1 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF5410 PF17422.2 RJW68835.1 - 0.00046 19.6 5.2 0.0006 19.2 5.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5410) Endotoxin_N PF03945.14 RJW68835.1 - 0.15 11.8 1.3 5.3 6.7 0.0 2.1 1 1 0 2 2 2 0 delta endotoxin, N-terminal domain NUC130_3NT PF08158.12 RJW68835.1 - 0.36 11.2 4.4 0.25 11.7 0.7 2.6 3 0 0 3 3 3 0 NUC130/3NT domain Nop52 PF05997.12 RJW68836.1 - 1.4e-29 103.5 0.9 3.9e-29 102.0 0.9 1.8 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Integrase_H2C2 PF17921.1 RJW68837.1 - 7.2e-05 22.8 1.0 0.00016 21.7 1.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RJW68837.1 - 0.0026 18.0 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Ndr PF03096.14 RJW68838.1 - 1.5e-52 178.0 0.0 1.9e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 RJW68838.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Kelch_1 PF01344.25 RJW68840.1 - 8.4e-57 188.5 13.1 9.5e-12 44.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RJW68840.1 - 2.8e-33 113.1 3.5 1.3e-05 25.3 0.0 6.7 4 2 3 7 7 7 6 Kelch motif BTB PF00651.31 RJW68840.1 - 2.3e-27 95.4 1.6 3.5e-27 94.8 0.1 2.2 3 0 0 3 3 3 1 BTB/POZ domain Kelch_4 PF13418.6 RJW68840.1 - 7.3e-26 89.9 0.0 6e-06 26.2 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 RJW68840.1 - 1.8e-23 81.6 3.9 5e-06 26.3 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RJW68840.1 - 1.2e-15 57.4 0.5 1.2e-05 25.4 0.0 6.1 6 0 0 6 6 6 2 Galactose oxidase, central domain BACK PF07707.15 RJW68840.1 - 1.1e-13 51.2 2.8 3.1e-13 49.7 0.9 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 RJW68840.1 - 1.7e-06 27.9 7.7 0.18 11.8 0.0 5.9 6 0 0 6 6 6 2 Kelch motif zf-C2H2_4 PF13894.6 RJW68841.1 - 7e-13 48.2 42.5 0.0048 17.6 5.1 6.0 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW68841.1 - 3.7e-12 46.0 42.4 0.00013 22.2 4.7 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 RJW68841.1 - 5.6e-05 22.8 4.7 0.0062 16.3 1.6 5.9 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-met PF12874.7 RJW68841.1 - 0.0002 21.6 32.3 0.084 13.3 0.2 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 RJW68841.1 - 0.0002 21.6 38.9 0.045 14.2 0.3 6.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW68841.1 - 0.0045 17.2 0.1 0.0045 17.2 0.1 4.8 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW68841.1 - 0.019 15.0 4.3 0.019 15.0 4.3 5.2 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 RJW68841.1 - 0.97 9.3 7.6 7.7 6.4 0.2 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 RJW68841.1 - 5 6.8 11.5 12 5.7 0.8 3.6 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 RJW68841.1 - 8.8 6.0 16.7 0.7 9.5 0.6 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger CSRNP_N PF16019.5 RJW68842.1 - 7.3e-68 228.8 21.4 7.3e-68 228.8 21.4 2.6 2 1 0 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus Lum_binding PF00677.17 RJW68843.1 - 0.018 15.0 0.3 0.028 14.4 0.3 1.3 1 1 0 1 1 1 0 Lumazine binding domain FOXP-CC PF16159.5 RJW68844.1 - 1.7e-05 25.3 27.4 1.1 9.9 0.5 6.8 3 2 3 6 6 6 4 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 RJW68844.1 - 2.1e-05 25.0 54.4 0.064 14.1 0.5 8.2 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW68844.1 - 0.076 13.5 0.7 0.076 13.5 0.7 7.2 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 RJW68844.1 - 0.094 13.0 20.2 0.1 12.9 1.6 4.5 1 1 4 5 5 5 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 RJW68844.1 - 3.8 7.6 29.0 16 5.6 0.2 6.0 2 2 5 7 7 7 0 Aberrant zinc-finger Calponin PF00402.18 RJW68845.1 - 1.7e-62 206.6 46.6 9.6e-13 47.5 3.5 5.5 5 0 0 5 5 5 5 Calponin family repeat CH PF00307.31 RJW68845.1 - 6.7e-20 71.3 0.0 9.2e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Beta-APP PF03494.13 RJW68845.1 - 0.2 11.6 6.5 10 6.1 0.3 3.7 4 0 0 4 4 4 0 Beta-amyloid peptide (beta-APP) Tubulin PF00091.25 RJW68847.1 - 2e-64 217.4 0.0 3e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW68847.1 - 5e-33 113.9 0.4 9.9e-33 113.0 0.4 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RJW68847.1 - 1.8e-05 25.1 0.0 3.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 RJW68847.1 - 0.14 11.3 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin like UPF0114 PF03350.16 RJW68849.1 - 0.01 16.1 0.3 0.019 15.1 0.3 1.6 1 1 0 1 1 1 1 Uncharacterized protein family, UPF0114 Trypsin PF00089.26 RJW68851.1 - 2.9e-28 99.2 0.0 3.6e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin Peptidase_C2 PF00648.21 RJW68853.1 - 1.6e-25 89.8 0.1 3e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RJW68853.1 - 2.3e-24 86.3 0.1 8.9e-24 84.4 0.0 2.0 2 0 0 2 2 2 1 Calpain large subunit, domain III E1-N PF14463.6 RJW68855.1 - 0.2 11.4 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 E1 N-terminal domain Peptidase_A17 PF05380.13 RJW68856.1 - 6.6e-25 88.0 0.0 5.6e-24 85.0 0.0 2.0 1 1 0 1 1 1 1 Pao retrotransposon peptidase Ras PF00071.22 RJW68858.1 - 5.2e-26 91.2 0.1 2.4e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RJW68858.1 - 9.5e-05 22.6 0.0 0.0003 21.0 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 RJW68858.1 - 0.093 13.2 0.1 0.093 13.2 0.1 1.8 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 RJW68858.1 - 0.097 13.2 0.3 0.46 11.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RJW68858.1 - 0.098 12.4 0.3 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arf PF00025.21 RJW68858.1 - 0.14 11.6 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family SMC_N PF02463.19 RJW68858.1 - 0.16 11.4 1.3 0.22 10.9 0.2 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain TIG PF01833.24 RJW68859.1 - 0.027 14.5 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 IPT/TIG domain RT_RNaseH PF17917.1 RJW68861.1 - 2.7e-07 30.8 0.0 3.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW68861.1 - 0.033 14.2 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-DBF PF07535.12 RJW68862.1 - 9.6e-17 60.8 1.7 1.7e-16 60.0 1.7 1.4 1 0 0 1 1 1 1 DBF zinc finger OB_NTP_bind PF07717.16 RJW68864.1 - 2e-24 85.8 0.0 4.3e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 RJW68864.1 - 4.9e-24 84.7 0.1 4.9e-24 84.7 0.1 3.2 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RJW68864.1 - 1.4e-13 51.2 0.0 4.5e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 RJW68864.1 - 1.2e-09 38.4 0.2 2.5e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 RJW68864.1 - 1.4e-06 28.2 1.2 3.3e-06 27.0 0.1 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RJW68864.1 - 4.3e-05 23.8 0.1 0.00063 20.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RJW68864.1 - 0.00074 19.9 0.3 0.0036 17.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 RJW68864.1 - 0.0038 16.3 0.3 0.014 14.5 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 RJW68864.1 - 0.0057 16.4 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 RJW68864.1 - 0.029 14.2 0.9 0.94 9.3 0.0 3.4 3 1 1 4 4 4 0 Helicase AAA_7 PF12775.7 RJW68864.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CTD_bind PF04818.13 RJW68865.1 - 1.2e-09 38.9 0.1 3.7e-08 34.1 0.1 2.9 3 0 0 3 3 3 1 RNA polymerase II-binding domain. CREPT PF16566.5 RJW68865.1 - 0.011 15.9 3.4 0.035 14.3 3.4 1.9 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Peptidase_C2 PF00648.21 RJW68867.1 - 2.1e-116 388.2 0.0 2.9e-116 387.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RJW68867.1 - 1.3e-39 135.7 0.0 2.2e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 RJW68867.1 - 2e-07 30.0 0.0 0.0032 16.9 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RJW68867.1 - 1.8e-06 27.4 0.4 0.00068 19.4 0.0 3.7 2 1 1 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 RJW68867.1 - 3.5e-05 24.2 6.9 0.0047 17.4 0.2 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 RJW68867.1 - 3.9e-05 23.4 0.0 0.00091 19.0 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair AvrB_AvrC PF05394.11 RJW68867.1 - 0.062 12.5 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Avirulence protein GTP_EFTU PF00009.27 RJW68869.1 - 4.9e-54 182.8 0.0 7e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RJW68869.1 - 4.4e-41 139.7 0.0 1e-40 138.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RJW68869.1 - 8e-15 55.0 0.9 1.9e-14 53.8 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RJW68869.1 - 0.00054 20.0 0.1 0.016 15.3 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 RJW68869.1 - 0.0099 15.8 0.2 0.0099 15.8 0.2 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 4 O-FucT PF10250.9 RJW68871.1 - 2.3e-49 168.9 0.0 4.2e-49 168.1 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Bclx_interact PF08945.10 RJW68871.1 - 0.19 11.5 2.3 0.25 11.1 0.1 2.3 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain C2 PF00168.30 RJW68872.1 - 1.8e-48 163.1 1.2 4.9e-26 91.0 0.2 4.0 4 0 0 4 4 4 3 C2 domain Membr_traf_MHD PF10540.9 RJW68872.1 - 1.4e-42 145.3 1.0 3.7e-42 144.0 1.0 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.17 RJW68872.1 - 3.7e-32 110.8 3.6 4.6e-30 104.1 0.2 2.8 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 RJW68872.1 - 1.4e-10 40.9 5.9 1.4e-10 40.9 5.9 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CEP76-C2 PF15627.6 RJW68872.1 - 0.0074 15.9 0.0 0.93 9.0 0.0 2.6 2 0 0 2 2 2 1 CEP76 C2 domain DUF5401 PF17380.2 RJW68872.1 - 7.3 4.5 8.1 13 3.6 8.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Amido_AtzD_TrzD PF09663.10 RJW68874.1 - 0.14 11.1 0.1 0.17 10.9 0.1 1.0 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Pkinase PF00069.25 RJW68875.1 - 3.2e-41 141.5 0.1 1.3e-37 129.7 0.0 3.9 3 1 1 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68875.1 - 1e-17 64.3 0.0 3.1e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW68875.1 - 0.0014 17.5 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW68875.1 - 0.063 12.6 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Bcl-2 PF00452.19 RJW68877.1 - 4.1e-15 56.3 0.8 2.2e-14 53.9 0.3 2.3 1 1 1 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family COesterase PF00135.28 RJW68878.1 - 3.5e-138 461.7 0.0 4.7e-138 461.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RJW68878.1 - 1.4e-07 31.6 0.1 3.9e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RJW68878.1 - 0.037 13.5 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Herpes_U47 PF05467.11 RJW68879.1 - 0.77 7.8 5.5 0.097 10.8 1.7 1.4 2 0 0 2 2 2 0 Herpesvirus glycoprotein U47 Cupin_2 PF07883.11 RJW68882.1 - 2.8e-12 46.1 0.0 3.6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 RJW68882.1 - 9.9e-06 25.5 0.0 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.14 RJW68882.1 - 0.017 15.3 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_4 PF08007.12 RJW68882.1 - 0.067 12.6 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_7 PF12973.7 RJW68882.1 - 0.084 12.8 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 ChrR Cupin-like domain DMSP_lyase PF16867.5 RJW68882.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Cupin_1 PF00190.22 RJW68882.1 - 0.13 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Cupin Ccdc124 PF06244.12 RJW68884.1 - 8.5e-34 116.9 5.7 8.5e-34 116.9 5.7 2.3 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 RJW68884.1 - 0.029 14.3 0.1 0.059 13.3 0.1 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain Pkinase PF00069.25 RJW68886.1 - 1.4e-71 241.0 0.0 1.7e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68886.1 - 7.5e-37 127.0 0.0 9.4e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RJW68886.1 - 9.3e-14 51.8 0.1 2e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 RJW68886.1 - 3.4e-08 33.1 0.0 6.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 RJW68886.1 - 0.002 18.8 0.5 0.0044 17.7 0.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.6 RJW68886.1 - 0.042 14.3 0.4 0.38 11.2 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Haspin_kinase PF12330.8 RJW68886.1 - 0.064 12.2 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain WIF PF02019.18 RJW68890.1 - 3e-16 59.3 0.0 5.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 WIF domain BSMAP PF12280.8 RJW68890.1 - 0.069 13.4 1.7 0.11 12.7 1.7 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein Tetraspanin PF00335.20 RJW68891.1 - 1.9e-49 168.4 10.1 2.2e-49 168.3 10.1 1.0 1 0 0 1 1 1 1 Tetraspanin family EI24 PF07264.11 RJW68891.1 - 0.0027 18.0 0.4 0.011 16.0 0.4 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Amastin PF07344.11 RJW68891.1 - 2 8.3 13.4 4 7.3 0.7 2.8 2 1 0 2 2 2 0 Amastin surface glycoprotein Spec3 PF15795.5 RJW68891.1 - 2.3 8.8 9.6 1.9 9.1 2.9 2.9 2 1 1 3 3 3 0 Ectodermal ciliogenesis protein LIM PF00412.22 RJW68892.1 - 7.9e-25 86.9 27.2 3.1e-12 46.5 9.0 2.3 2 0 0 2 2 2 2 LIM domain FERM_M PF00373.18 RJW68893.1 - 5.8e-19 68.6 0.0 1.1e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 RJW68893.1 - 2.3e-07 31.1 0.3 6e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 FERM C-terminal PH-like domain YcxB PF14317.6 RJW68893.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 YcxB-like protein BORCS6 PF10157.9 RJW68895.1 - 3.7e-32 111.7 0.2 4.2e-32 111.5 0.2 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Ig_C17orf99 PF17736.1 RJW68895.1 - 0.035 14.1 0.1 0.38 10.8 0.1 2.1 2 0 0 2 2 2 0 C17orf99 Ig domain RPW8 PF05659.11 RJW68895.1 - 0.046 13.4 0.3 0.16 11.6 0.2 1.8 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Sec34 PF04136.15 RJW68895.1 - 0.06 13.2 0.5 0.36 10.7 0.4 2.0 1 1 0 1 1 1 0 Sec34-like family QVR PF17064.5 RJW68896.1 - 4.2e-27 94.2 12.2 6.7e-27 93.6 12.2 1.3 1 0 0 1 1 1 1 Sleepless protein DUF753 PF05444.12 RJW68896.1 - 0.0016 18.4 6.6 0.0016 18.4 6.6 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF753) Activin_recp PF01064.23 RJW68896.1 - 0.32 12.1 12.6 0.6 11.2 12.6 1.4 1 0 0 1 1 1 0 Activin types I and II receptor domain DNA_primase_S PF01896.19 RJW68897.1 - 1.3e-14 54.7 0.0 1.9e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 DNA primase small subunit ETF_QO PF05187.13 RJW68897.1 - 0.095 12.8 0.0 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FKBP_C PF00254.28 RJW68900.1 - 4.2e-20 71.9 0.2 2.3e-19 69.5 0.4 2.0 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 RJW68900.1 - 3.2e-13 48.9 1.5 1.1e-05 25.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW68900.1 - 1.3e-09 37.5 2.7 7.3e-05 22.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 RJW68900.1 - 3.4e-07 30.5 0.1 0.0018 18.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW68900.1 - 1.3e-06 28.9 0.0 0.0011 19.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW68900.1 - 5.1e-06 26.9 0.1 0.00087 19.9 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW68900.1 - 2.8e-05 24.3 3.3 0.22 11.8 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat FKBP_N_2 PF18023.1 RJW68900.1 - 4e-05 23.7 0.0 0.0025 17.9 0.0 3.1 4 0 0 4 4 4 1 BDBT FKBP like N-terminal TPR_8 PF13181.6 RJW68900.1 - 7.4e-05 22.7 0.3 0.13 12.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RJW68900.1 - 8.2e-05 23.0 0.3 0.013 16.0 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RJW68900.1 - 0.0018 18.3 1.5 0.96 9.6 0.1 3.1 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 RJW68900.1 - 0.013 15.7 2.4 0.16 12.2 0.2 2.8 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RJW68900.1 - 0.017 15.5 1.7 0.19 12.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW68900.1 - 0.051 13.6 3.8 6.6 7.0 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 RJW68900.1 - 0.13 12.6 0.3 0.44 10.9 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Med30 PF11315.8 RJW68902.1 - 0.0023 18.2 4.8 0.0023 18.2 4.8 2.0 1 1 1 2 2 2 1 Mediator complex subunit 30 DHR10 PF18595.1 RJW68902.1 - 0.052 13.6 14.4 0.035 14.2 12.8 1.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain UPF0184 PF03670.13 RJW68902.1 - 0.062 13.7 4.2 0.094 13.1 0.7 2.7 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0184) DUF724 PF05266.14 RJW68902.1 - 0.52 10.1 9.0 0.76 9.6 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4446 PF14584.6 RJW68902.1 - 1 9.3 6.6 0.19 11.7 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) OmpH PF03938.14 RJW68902.1 - 2.9 8.2 10.2 0.51 10.7 6.0 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Myb_DNA-bind_7 PF15963.5 RJW68904.1 - 1.4e-24 85.8 1.2 2.6e-24 84.9 1.2 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 RJW68904.1 - 0.014 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Thymosin PF01290.20 RJW68905.1 - 9.7e-34 114.8 31.0 9.1e-13 47.7 1.4 4.2 2 1 2 4 4 4 4 Thymosin beta-4 family WH2 PF02205.20 RJW68905.1 - 5.1e-09 35.7 0.2 0.0032 17.3 0.0 4.2 4 0 0 4 4 4 2 WH2 motif INCA1 PF15142.6 RJW68905.1 - 0.021 14.9 2.3 1.9 8.5 0.2 2.6 2 1 1 3 3 3 0 INCA1 WDCP PF15390.6 RJW68905.1 - 0.033 12.6 4.5 0.037 12.4 4.5 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DicB PF05358.11 RJW68905.1 - 0.19 11.9 1.3 18 5.6 0.1 2.7 1 1 2 3 3 3 0 DicB protein CAP PF00188.26 RJW68906.1 - 1.1e-08 36.0 0.2 4.6e-08 34.0 0.2 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Integrin_alpha2 PF08441.12 RJW68907.1 - 1.5e-28 99.9 0.0 9.8e-28 97.2 0.0 2.0 1 1 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 RJW68907.1 - 4.2e-16 58.7 11.6 2.5e-06 27.5 0.5 4.0 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.6 RJW68907.1 - 1.5e-06 28.7 6.0 0.12 13.0 0.0 3.7 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 RJW68907.1 - 0.03 13.7 0.1 4.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region RVT_1 PF00078.27 RJW68909.1 - 7.2e-27 94.4 0.0 1.6e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH2 PF00017.24 RJW68909.1 - 2.2e-16 59.7 0.0 5.4e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 SH2 domain FOG_N PF15888.5 RJW68909.1 - 0.048 14.0 0.0 0.2 12.0 0.0 2.0 1 0 0 1 1 1 0 Folded gastrulation N-terminus PSS PF03034.15 RJW68910.1 - 6.6e-74 249.1 8.6 7.8e-74 248.8 8.6 1.0 1 0 0 1 1 1 1 Phosphatidyl serine synthase Atracotoxin PF05353.11 RJW68911.1 - 0.042 13.9 0.1 0.062 13.4 0.1 1.2 1 0 0 1 1 1 0 Delta Atracotoxin DUF3342 PF11822.8 RJW68912.1 - 0.059 13.6 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) YdjC PF04794.12 RJW68913.1 - 1.3e-58 198.8 0.0 1.5e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein JAKMIP_CC3 PF16034.5 RJW68915.1 - 0.013 15.5 2.6 0.014 15.4 2.6 1.0 1 0 0 1 1 1 0 JAKMIP CC3 domain KinB_sensor PF16767.5 RJW68915.1 - 0.043 14.3 2.7 0.061 13.8 2.7 1.1 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF948 PF06103.11 RJW68915.1 - 0.08 13.2 1.5 0.095 13.0 1.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Rop-like PF05082.13 RJW68915.1 - 0.099 12.5 0.3 0.55 10.1 0.1 2.0 1 1 1 2 2 2 0 Rop-like RabGAP-TBC PF00566.18 RJW68916.1 - 1e-22 80.8 7.3 3e-11 43.4 1.1 2.9 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Leucyl-specific PF14795.6 RJW68916.1 - 0.045 13.8 0.1 0.097 12.7 0.1 1.5 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain Cytochrom_C552 PF02335.15 RJW68916.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c552 HALZ PF02183.18 RJW68920.1 - 0.056 13.7 10.8 12 6.2 0.3 4.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper PSD5 PF07637.11 RJW68920.1 - 0.23 11.9 7.6 0.99 9.8 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) ATG16 PF08614.11 RJW68920.1 - 0.26 11.5 87.4 0.15 12.2 1.1 7.3 3 3 3 6 6 6 0 Autophagy protein 16 (ATG16) TraF_2 PF13729.6 RJW68920.1 - 0.65 9.3 2.7 14 4.9 0.2 3.2 3 0 0 3 3 3 0 F plasmid transfer operon, TraF, protein Pox_A_type_inc PF04508.12 RJW68920.1 - 0.81 9.6 0.0 0.81 9.6 0.0 6.8 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat DUF3138 PF11336.8 RJW68920.1 - 1.6 7.2 4.9 1.2 7.7 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) WXG100 PF06013.12 RJW68920.1 - 5.1 7.4 17.2 1.2 9.4 0.1 6.0 4 1 1 5 5 5 0 Proteins of 100 residues with WXG APG6_N PF17675.1 RJW68920.1 - 5.4 7.5 78.1 0.17 12.4 21.3 6.3 3 3 2 5 5 5 0 Apg6 coiled-coil region LAMTOR5 PF16672.5 RJW68921.1 - 0.052 13.5 0.1 2.9 7.9 0.0 2.3 1 1 1 2 2 2 0 Ragulator complex protein LAMTOR5 LuxC PF05893.14 RJW68921.1 - 0.067 12.2 0.3 0.1 11.6 0.3 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) zf-C2HC_2 PF13913.6 RJW68923.1 - 7.6 6.6 7.7 4.5 7.3 0.7 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type CH PF00307.31 RJW68924.1 - 5.1e-21 74.9 0.0 6.2e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW68924.1 - 2.1e-05 24.3 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain RVP_2 PF08284.11 RJW68926.1 - 1.1e-05 25.2 0.3 3.9e-05 23.4 0.3 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 RJW68926.1 - 0.0021 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 RJW68926.1 - 0.0022 18.6 0.0 0.0041 17.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW68926.1 - 0.0045 17.5 0.0 0.011 16.3 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 RJW68926.1 - 0.049 13.4 0.1 0.24 11.2 0.1 1.9 1 1 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 RJW68926.1 - 0.064 13.4 3.4 0.064 13.4 3.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 RJW68926.1 - 0.53 10.0 12.0 1.9 8.3 0.4 2.5 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 RJW68926.1 - 7.6 6.5 11.6 0.097 12.5 4.0 1.9 2 0 0 2 2 2 0 Zinc knuckle P53 PF00870.18 RJW68927.1 - 4e-24 85.5 0.5 7.6e-24 84.5 0.5 1.4 1 1 0 1 1 1 1 P53 DNA-binding domain CAP PF00188.26 RJW68928.1 - 6e-10 40.0 3.9 1.3e-08 35.8 3.9 2.1 1 1 0 1 1 1 1 Cysteine-rich secretory protein family IFT57 PF10498.9 RJW68929.1 - 0.2 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TraO PF10626.9 RJW68930.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Conjugative transposon protein TraO RVT_1 PF00078.27 RJW68931.1 - 0.0015 18.1 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fasciclin PF02469.22 RJW68934.1 - 2.1e-37 128.2 0.0 1.2e-09 38.5 0.0 4.3 4 0 0 4 4 4 4 Fasciclin domain PRELI PF04707.14 RJW68935.1 - 4.4e-24 85.1 0.2 9.1e-24 84.1 0.2 1.5 1 0 0 1 1 1 1 PRELI-like family Autophagy_N PF03986.13 RJW68935.1 - 0.097 12.6 0.2 0.097 12.6 0.2 2.0 1 1 1 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain PHO4 PF01384.20 RJW68936.1 - 1.5 7.8 12.3 1.9 7.4 12.3 1.2 1 0 0 1 1 1 0 Phosphate transporter family Wzy_C PF04932.15 RJW68936.1 - 2.7 7.6 8.3 3.7 7.1 8.3 1.3 1 0 0 1 1 1 0 O-Antigen ligase UPF0182 PF03699.13 RJW68936.1 - 4.5 5.3 16.5 5.4 5.0 16.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Tmpp129 PF10272.9 RJW68936.1 - 8.1 5.6 15.0 9.9 5.3 15.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Tetraspanin PF00335.20 RJW68937.1 - 1.4e-34 119.8 22.1 1.6e-34 119.6 22.1 1.0 1 0 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 RJW68938.1 - 4.8e-37 127.9 24.0 5.4e-37 127.7 24.0 1.0 1 0 0 1 1 1 1 Tetraspanin family Phage_holin_3_6 PF07332.11 RJW68938.1 - 6.5 6.8 17.8 0.12 12.5 2.8 2.9 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2975 PF11188.8 RJW68938.1 - 9.1 6.2 13.3 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DNA_pol_phi PF04931.13 RJW68939.1 - 0.00051 18.3 37.1 0.00068 17.9 37.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 RJW68939.1 - 0.0025 17.3 25.7 0.0027 17.2 25.7 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 RJW68939.1 - 0.054 11.8 22.7 0.076 11.3 22.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RJW68939.1 - 0.096 10.9 31.1 0.11 10.6 31.1 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 RJW68939.1 - 0.15 10.4 19.9 0.19 10.1 19.9 1.2 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 RJW68939.1 - 2.1 7.0 7.2 2 7.1 7.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tetraspanin PF00335.20 RJW68940.1 - 8.5e-16 58.4 11.0 1.1e-15 58.1 11.0 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3592 PF12158.8 RJW68940.1 - 0.053 13.6 0.6 0.053 13.6 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) DUF2964 PF11177.8 RJW68940.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) DUF2070 PF09843.9 RJW68940.1 - 1.3 7.2 10.9 2 6.6 10.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Gram_pos_anchor PF00746.21 RJW68940.1 - 9.6 6.3 6.7 0.36 10.8 0.5 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Branch PF02485.21 RJW68941.1 - 5.3e-34 117.8 0.0 8.2e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Histone PF00125.24 RJW68943.1 - 1e-22 80.9 2.1 1.3e-22 80.6 2.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RJW68943.1 - 2e-06 28.0 0.1 4.8e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 RJW68943.1 - 0.00038 20.5 1.2 0.00045 20.3 1.2 1.2 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 RJW68943.1 - 0.00049 20.5 0.0 0.0009 19.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CNDH2_C PF16858.5 RJW68943.1 - 0.0027 17.6 0.9 0.0028 17.6 0.9 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF3915 PF13054.6 RJW68943.1 - 0.06 13.3 0.1 0.069 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) WD40 PF00400.32 RJW68945.1 - 6e-13 49.0 1.7 0.0002 22.1 0.1 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW68945.1 - 0.0029 17.9 0.0 0.3 11.4 0.1 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2729 PF10870.8 RJW68945.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) Pentapeptide_4 PF13599.6 RJW68946.1 - 0.00018 21.6 12.1 3.7e+02 1.4 12.1 3.9 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) CfAFP PF05264.11 RJW68946.1 - 0.0018 18.2 59.0 6e+03 -2.9 0.1 4.2 2 1 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Hamartin PF04388.12 RJW68946.1 - 2 7.0 47.5 2.5 6.6 47.5 1.1 1 0 0 1 1 1 0 Hamartin protein Tetraspanin PF00335.20 RJW68947.1 - 3.1e-32 112.1 17.4 3.5e-32 112.0 17.4 1.0 1 0 0 1 1 1 1 Tetraspanin family CYYR1 PF10873.8 RJW68947.1 - 0.019 15.4 1.9 0.019 15.4 1.9 2.4 2 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 B277 PF17623.2 RJW68947.1 - 0.087 11.9 0.6 0.14 11.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function PHO4 PF01384.20 RJW68947.1 - 6.5 5.7 7.4 9.1 5.2 7.4 1.4 1 1 0 1 1 1 0 Phosphate transporter family ABC2_membrane_2 PF12679.7 RJW68947.1 - 8.8 5.5 13.6 0.38 10.0 6.7 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein C2 PF00168.30 RJW68948.1 - 7.9e-06 26.1 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Glyco_trans_4_4 PF13579.6 RJW68949.1 - 6.1e-07 30.0 0.3 1.8e-06 28.5 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 RJW68949.1 - 6.4e-06 26.3 0.8 4e-05 23.7 0.1 2.3 2 1 1 3 3 3 1 Glycosyltransferase Family 4 RVT_1 PF00078.27 RJW68949.1 - 2.1e-05 24.2 0.0 3.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cbl_N PF02262.16 RJW68950.1 - 8.7e-46 155.0 0.8 1.7e-45 154.0 0.4 1.7 2 0 0 2 2 2 1 CBL proto-oncogene N-terminal domain 1 Cbl_N3 PF02762.14 RJW68950.1 - 4.5e-41 138.6 0.0 7.8e-41 137.8 0.0 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 RJW68950.1 - 1.8e-33 115.1 2.0 5e-33 113.7 2.0 1.8 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Prok-RING_4 PF14447.6 RJW68950.1 - 3.5e-12 46.0 7.1 3.5e-12 46.0 7.1 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RJW68950.1 - 3.4e-11 42.8 5.5 3.4e-11 42.8 5.5 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW68950.1 - 1.6e-06 28.3 8.1 1.6e-06 28.3 8.1 2.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 RJW68950.1 - 1.7e-06 27.8 9.0 5.3e-06 26.2 9.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW68950.1 - 6.9e-05 22.7 7.4 6.9e-05 22.7 7.4 2.3 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 RJW68950.1 - 0.00017 21.3 6.2 0.00059 19.6 6.2 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 RJW68950.1 - 0.00032 20.7 6.4 0.00032 20.7 6.4 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RJW68950.1 - 0.00052 19.8 8.8 0.0013 18.5 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DLP_helical PF18709.1 RJW68950.1 - 0.092 11.9 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain SNARE PF05739.19 RJW68951.1 - 2e-15 56.5 0.2 5.6e-15 55.1 0.2 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 RJW68951.1 - 0.0019 17.9 11.4 0.039 13.6 0.1 2.6 2 1 0 2 2 2 2 Syntaxin DUF16 PF01519.16 RJW68951.1 - 0.0023 18.4 2.4 0.034 14.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function DUF16 MCPsignal PF00015.21 RJW68951.1 - 0.36 10.6 7.4 0.091 12.6 0.8 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ISG65-75 PF11727.8 RJW68951.1 - 0.44 9.7 2.0 3.2 6.9 0.2 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein KxDL PF10241.9 RJW68951.1 - 2.1 8.7 7.5 1.9 8.8 0.1 3.6 2 1 2 4 4 4 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 RJW68951.1 - 2.5 8.7 6.9 2.6 8.7 1.1 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Potex_coat PF06184.11 RJW68952.1 - 0.026 14.1 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 Potexvirus coat protein SNF2_N PF00176.23 RJW68953.1 - 0.061 12.0 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ribosomal_L44 PF00935.19 RJW68954.1 - 2.8e-35 120.6 12.9 4.1e-35 120.1 12.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 RNA_POL_M_15KD PF02150.16 RJW68954.1 - 0.033 14.1 0.8 0.064 13.1 0.1 1.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit LRV_FeS PF05484.11 RJW68954.1 - 0.16 12.0 4.5 1.5 8.9 0.3 2.2 2 0 0 2 2 2 0 LRV protein FeS4 cluster EF-hand_7 PF13499.6 RJW68955.1 - 4.5e-22 78.3 2.1 1.3e-09 38.4 1.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW68955.1 - 6.5e-22 75.4 2.2 5.3e-06 25.6 0.3 4.8 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 RJW68955.1 - 4.4e-19 66.7 2.9 3.3e-06 26.6 0.1 5.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 RJW68955.1 - 1.3e-15 57.0 6.3 7.4e-07 28.9 0.1 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW68955.1 - 1.2e-13 49.9 0.6 0.00034 20.0 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 RJW68955.1 - 0.0004 20.6 0.0 1.3 9.4 0.0 3.4 3 1 0 3 3 3 1 EF-hand domain Thymidylat_synt PF00303.19 RJW68955.1 - 0.014 14.6 0.1 0.024 13.8 0.1 1.3 1 1 0 1 1 1 0 Thymidylate synthase TerB PF05099.13 RJW68955.1 - 0.083 12.8 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB Toprim_2 PF13155.6 RJW68955.1 - 0.15 12.5 0.1 7.3 7.1 0.0 2.6 1 1 2 3 3 3 0 Toprim-like HipA_C PF07804.12 RJW68955.1 - 0.26 10.9 2.0 1.4 8.5 0.4 2.2 1 1 2 3 3 3 0 HipA-like C-terminal domain CPL PF08144.11 RJW68956.1 - 1.7e-10 41.4 0.1 2.4e-09 37.7 0.1 2.9 3 0 0 3 3 3 1 CPL (NUC119) domain Brix PF04427.18 RJW68957.1 - 2.4e-24 86.5 0.0 3.3e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain Pkinase PF00069.25 RJW68958.1 - 1e-23 84.1 0.0 2.2e-11 43.6 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RJW68958.1 - 4.3e-13 49.2 0.0 4.3e-07 29.5 0.0 4.0 4 0 0 4 4 4 3 Protein tyrosine kinase Kdo PF06293.14 RJW68958.1 - 0.033 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Integrin_B_tail PF07965.12 RJW68960.1 - 0.15 12.6 7.4 0.33 11.5 7.4 1.6 1 1 0 1 1 1 0 Integrin beta tail domain PAN_1 PF00024.26 RJW68960.1 - 5.6 7.0 13.2 0.14 12.1 3.3 2.3 1 1 2 3 3 3 0 PAN domain Tmemb_9 PF05434.11 RJW68961.1 - 5.1e-33 114.0 0.1 6.1e-24 84.6 0.1 2.5 2 0 0 2 2 2 2 TMEM9 RVT_1 PF00078.27 RJW68961.1 - 9.6e-13 48.2 0.1 4.3e-12 46.0 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gemini_mov PF01708.16 RJW68961.1 - 0.13 12.0 0.4 0.38 10.6 0.4 1.7 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF842 PF05811.13 RJW68962.1 - 0.0092 15.7 6.0 0.0092 15.7 6.0 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Phage_Coat_A PF05357.13 RJW68965.1 - 0.22 11.3 0.5 0.63 9.9 0.5 1.8 1 1 0 1 1 1 0 Phage Coat Protein A GIY-YIG PF01541.24 RJW68968.1 - 0.0026 18.0 0.2 0.0066 16.7 0.2 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF2034 PF10356.9 RJW68968.1 - 0.066 12.6 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) Ank PF00023.30 RJW68969.1 - 3.2e-15 55.8 5.6 7e-06 26.3 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 RJW68969.1 - 8.2e-15 55.0 0.1 0.013 16.0 0.0 5.4 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW68969.1 - 2.4e-12 47.2 0.0 1e-05 26.0 0.0 4.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW68969.1 - 2.6e-11 42.7 2.0 0.26 12.0 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat MORN PF02493.20 RJW68969.1 - 5.1e-08 32.3 19.0 0.0017 18.1 0.4 6.4 7 0 0 7 7 7 2 MORN repeat Ank_5 PF13857.6 RJW68969.1 - 0.0051 17.1 3.0 12 6.3 0.0 4.5 5 1 0 5 5 5 1 Ankyrin repeats (many copies) EF-hand_7 PF13499.6 RJW68970.1 - 6.1e-06 26.6 0.1 0.063 13.7 0.0 3.5 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW68970.1 - 0.00027 20.6 0.1 4.2 7.6 0.0 4.4 4 0 0 4 4 4 1 EF-hand domain FANCI_HD2 PF14680.6 RJW68970.1 - 0.073 12.3 0.3 0.12 11.6 0.3 1.3 1 0 0 1 1 1 0 FANCI helical domain 2 NT-C2 PF10358.9 RJW68971.1 - 2.2e-10 40.4 0.0 3.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins AMP-binding PF00501.28 RJW68973.1 - 2.4e-79 266.9 0.0 1.5e-60 205.0 0.0 2.7 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 RJW68973.1 - 0.08 13.9 0.1 0.29 12.1 0.0 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Mad3_BUB1_I PF08311.12 RJW68974.1 - 0.11 12.5 0.0 4.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 PAN_1 PF00024.26 RJW68975.1 - 1.5 8.8 12.4 41 4.2 12.4 2.7 1 1 0 1 1 1 0 PAN domain DUF3586 PF12131.8 RJW68976.1 - 1.7 8.9 7.2 0.61 10.3 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3586) PAN_1 PF00024.26 RJW68977.1 - 1.1 9.3 9.2 0.87 9.6 4.0 2.0 1 1 1 2 2 2 0 PAN domain BAH PF01426.18 RJW68978.1 - 3.6e-17 62.3 0.8 8.7e-17 61.1 0.1 2.0 3 0 0 3 3 3 1 BAH domain ELM2 PF01448.24 RJW68978.1 - 2.5e-07 31.3 0.0 7e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 ELM2 domain GATA PF00320.27 RJW68978.1 - 4.8e-06 26.1 7.1 1.1e-05 24.9 7.1 1.7 1 0 0 1 1 1 1 GATA zinc finger MTA_R1 PF17226.2 RJW68978.1 - 0.00032 20.8 1.0 0.00094 19.3 1.0 1.7 1 0 0 1 1 1 1 MTA R1 domain TMEM119 PF15724.5 RJW68978.1 - 0.14 12.2 0.0 0.14 12.2 0.0 2.5 3 0 0 3 3 3 0 TMEM119 family Myb_DNA-binding PF00249.31 RJW68978.1 - 0.16 12.2 0.1 0.4 10.9 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-C2H2 PF00096.26 RJW68979.1 - 2.2e-10 40.4 29.7 0.01 16.2 0.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW68979.1 - 2.8e-09 37.0 33.1 1.8e-05 24.9 3.9 5.2 5 1 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW68979.1 - 4e-09 36.6 30.5 0.04 14.8 4.4 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW68979.1 - 0.00058 20.1 15.4 1 9.8 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.12 RJW68979.1 - 0.0016 18.3 4.4 0.0016 18.3 4.4 2.5 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger zf-met PF12874.7 RJW68979.1 - 0.017 15.5 0.4 0.017 15.5 0.4 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RJW68979.1 - 0.018 15.0 23.5 0.053 13.5 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 RJW68979.1 - 0.055 13.8 19.9 0.88 9.9 4.6 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 RJW68979.1 - 0.067 13.0 9.7 0.12 12.2 1.8 2.6 2 0 0 2 2 2 0 GAGA factor Zn-C2H2_12 PF18112.1 RJW68979.1 - 0.27 11.7 9.5 0.63 10.6 0.7 3.9 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 RJW68979.1 - 0.5 10.7 17.7 0.72 10.2 2.3 3.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) RNA_POL_M_15KD PF02150.16 RJW68979.1 - 0.71 9.8 8.7 14 5.7 0.1 3.8 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-C2H2_3rep PF18868.1 RJW68979.1 - 1 10.1 9.1 6.2 7.5 8.4 2.7 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats TRAF6_Z2 PF18048.1 RJW68979.1 - 1.2 9.3 5.9 0.68 10.1 0.3 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Zn-ribbon_8 PF09723.10 RJW68979.1 - 1.7 8.8 15.9 4.5 7.5 0.3 4.3 3 1 1 4 4 4 0 Zinc ribbon domain zf-HIT PF04438.16 RJW68979.1 - 4.6 7.2 28.0 2.8 7.9 5.1 4.2 4 0 0 4 4 4 0 HIT zinc finger Actin_micro PF17003.5 RJW68979.1 - 9 5.4 8.3 5.5 6.1 0.5 2.5 1 1 1 2 2 2 0 Putative actin-like family zf-C2H2_4 PF13894.6 RJW68980.1 - 7.5e-11 41.9 31.1 0.0026 18.4 1.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW68980.1 - 1.7e-09 37.6 32.2 0.0011 19.3 1.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW68980.1 - 4.5e-06 26.9 28.6 0.0011 19.3 0.1 5.5 5 1 0 5 5 5 3 Zinc-finger double domain zf-met PF12874.7 RJW68980.1 - 0.015 15.7 2.5 0.31 11.5 0.2 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 RJW68980.1 - 0.026 14.1 11.6 2.2 7.9 0.4 4.1 3 1 1 4 4 4 0 MYST family zinc finger domain DZR PF12773.7 RJW68980.1 - 0.031 14.3 0.5 0.031 14.3 0.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_2 PF12756.7 RJW68980.1 - 0.093 13.1 12.9 11 6.4 0.5 3.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Rubredoxin PF00301.20 RJW68980.1 - 0.11 12.6 4.7 38 4.4 0.0 4.1 4 0 0 4 4 4 0 Rubredoxin zf_UBZ PF18439.1 RJW68980.1 - 0.22 11.2 3.9 1 9.0 0.5 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-HIT PF04438.16 RJW68980.1 - 0.26 11.2 17.2 0.34 10.8 1.9 4.2 4 0 0 4 4 4 0 HIT zinc finger zf-CCHC_5 PF14787.6 RJW68980.1 - 1.1 9.0 7.3 0.18 11.6 1.6 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger C1_4 PF07975.12 RJW68980.1 - 1.4 9.2 14.7 1.6 9.0 0.1 3.8 2 2 1 3 3 3 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 RJW68980.1 - 1.7 8.7 31.2 0.13 12.3 4.2 4.7 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW68980.1 - 1.7 9.0 0.1 1.7 9.0 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.21 RJW68980.1 - 2.3 8.4 22.2 36 4.6 1.0 3.2 1 1 1 2 2 2 0 FYVE zinc finger Ribosomal_L37ae PF01780.19 RJW68980.1 - 2.4 8.3 10.0 0.56 10.3 1.6 3.0 1 1 2 3 3 3 0 Ribosomal L37ae protein family zf-AN1 PF01428.16 RJW68980.1 - 4.9 7.4 16.1 0.49 10.6 0.7 4.0 4 0 0 4 4 4 0 AN1-like Zinc finger DUF3268 PF11672.8 RJW68980.1 - 5.8 7.3 9.3 0.51 10.7 1.6 2.6 2 1 0 2 2 2 0 zinc-finger-containing domain Zn-C2H2_12 PF18112.1 RJW68980.1 - 9.3 6.8 13.8 7.4 7.1 0.1 4.2 4 1 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain Ank_2 PF12796.7 RJW68981.1 - 1.1e-73 243.8 13.9 5.2e-12 46.2 0.6 7.7 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW68981.1 - 4.4e-62 205.7 17.3 1.8e-08 34.8 0.7 10.9 6 2 7 13 13 13 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW68981.1 - 2.2e-55 184.0 22.7 6.1e-07 29.6 0.0 13.1 2 2 11 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW68981.1 - 4.2e-54 174.2 16.4 0.00026 21.2 0.0 15.0 16 0 0 16 16 16 12 Ankyrin repeat Ank PF00023.30 RJW68981.1 - 1.2e-49 164.7 23.4 0.00067 20.0 0.0 14.9 15 0 0 15 15 15 13 Ankyrin repeat Ion_trans PF00520.31 RJW68981.1 - 1.8e-07 30.6 23.2 3.2e-07 29.8 23.2 1.4 1 0 0 1 1 1 1 Ion transport protein CLPTM1 PF05602.12 RJW68982.1 - 2e-138 462.1 1.7 2.5e-138 461.7 1.7 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 RJW68982.1 - 0.097 12.5 6.2 0.7 9.7 0.2 3.2 3 0 0 3 3 3 0 PQ loop repeat MCM PF00493.23 RJW68983.1 - 7e-97 322.9 0.0 1e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RJW68983.1 - 9.8e-31 106.2 0.0 1.6e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain RVT_1 PF00078.27 RJW68983.1 - 1.5e-29 103.2 0.0 2.5e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MCM_lid PF17855.1 RJW68983.1 - 2e-17 63.3 1.7 4.1e-17 62.4 1.7 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 RJW68983.1 - 2.5e-06 27.5 0.0 0.00091 19.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RJW68983.1 - 5.7e-06 25.9 0.0 7e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_lid_2 PF17863.1 RJW68983.1 - 0.019 14.8 0.5 0.046 13.6 0.5 1.6 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 RJW68983.1 - 0.046 13.6 0.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Nop14 PF04147.12 RJW68984.1 - 0.005 15.1 17.2 0.0047 15.2 17.2 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 RJW68984.1 - 0.0071 14.7 12.6 0.006 14.9 12.6 1.0 1 0 0 1 1 1 1 CDC45-like protein DNA_pol_phi PF04931.13 RJW68984.1 - 0.0081 14.3 33.6 0.009 14.2 33.6 1.0 1 0 0 1 1 1 1 DNA polymerase phi Mpp10 PF04006.12 RJW68984.1 - 0.018 13.5 10.6 0.018 13.5 10.6 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RJW68984.1 - 0.02 14.3 16.2 0.021 14.3 16.2 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 RJW68984.1 - 0.18 11.9 18.1 0.22 11.6 18.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CobT PF06213.12 RJW68984.1 - 0.37 10.1 14.4 0.45 9.9 14.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 RJW68984.1 - 5.1 6.3 20.2 5.9 6.1 20.2 1.1 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 RJW68984.1 - 6.3 6.5 13.6 8.6 6.1 13.6 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Roughex PF06020.11 RJW68984.1 - 8.6 5.3 12.1 8.6 5.3 12.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein eIF-3c_N PF05470.12 RJW68984.1 - 9.4 4.4 9.0 9.1 4.5 9.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus IFT57 PF10498.9 RJW68984.1 - 9.5 5.1 9.8 11 4.9 9.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CarboxypepD_reg PF13620.6 RJW68985.1 - 6.8e-25 87.2 7.1 5.4e-05 23.4 0.0 9.1 9 2 0 9 9 9 5 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 RJW68985.1 - 2.2e-12 47.2 0.0 0.13 12.5 0.0 7.2 7 1 0 7 7 7 2 SdrD B-like domain CarbopepD_reg_2 PF13715.6 RJW68985.1 - 1.1e-09 38.2 0.1 0.0056 16.7 0.0 6.5 7 0 0 7 7 7 2 CarboxypepD_reg-like domain SpaA PF17802.1 RJW68985.1 - 1.1e-07 32.1 0.0 0.2 12.0 0.0 4.0 3 0 0 3 3 3 3 Prealbumin-like fold domain fn3_3 PF14686.6 RJW68985.1 - 0.0059 16.4 0.1 50 3.8 0.0 4.7 4 0 0 4 4 4 0 Polysaccharide lyase family 4, domain II UDP-g_GGTase PF06427.11 RJW68985.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase Importin_rep_4 PF18808.1 RJW68986.1 - 1.3e-28 99.1 3.8 5.6e-28 97.1 1.7 3.3 2 0 0 2 2 2 1 Importin repeat HEAT PF02985.22 RJW68986.1 - 7.1e-22 75.6 2.0 0.00047 20.2 0.0 8.4 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 RJW68986.1 - 1.7e-16 60.3 4.7 1.1e-06 28.9 0.0 7.6 7 0 0 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 RJW68986.1 - 6.1e-15 55.4 6.3 2.3e-06 27.9 0.2 7.3 5 2 1 7 7 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 RJW68986.1 - 4.9e-11 43.1 0.2 0.00039 21.0 0.0 6.8 6 2 2 8 8 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RJW68986.1 - 5.2e-08 33.1 0.7 1.9e-06 28.0 0.0 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 RJW68986.1 - 6.9e-07 29.2 0.0 0.46 10.2 0.0 5.2 4 2 1 5 5 5 2 rRNA processing/ribosome biogenesis Importin_rep_6 PF18829.1 RJW68986.1 - 5e-05 23.4 4.3 0.00067 19.8 0.2 3.3 3 0 0 3 3 3 1 Importin repeat 6 CLASP_N PF12348.8 RJW68986.1 - 7e-05 22.5 0.0 0.08 12.5 0.0 3.8 3 0 0 3 3 3 1 CLASP N terminal DUF3385 PF11865.8 RJW68986.1 - 0.00031 20.7 0.6 2.4 8.1 0.1 5.2 5 2 2 7 7 7 1 Domain of unknown function (DUF3385) Arm PF00514.23 RJW68986.1 - 0.00056 19.9 0.9 0.081 13.0 0.2 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 RJW68986.1 - 0.00064 19.4 0.2 0.95 8.9 0.0 3.7 3 2 1 4 4 4 2 Tti2 family Importin_rep_5 PF18816.1 RJW68986.1 - 0.00082 19.6 0.0 0.018 15.4 0.0 3.0 2 0 0 2 2 2 1 Importin repeat MMS19_C PF12460.8 RJW68986.1 - 0.0039 16.3 5.9 0.89 8.6 0.1 4.2 4 2 0 4 4 4 2 RNAPII transcription regulator C-terminal HBB PF06777.11 RJW68986.1 - 0.02 14.6 0.1 0.056 13.1 0.1 1.7 1 0 0 1 1 1 0 Helical and beta-bridge domain DUF4061 PF13270.6 RJW68986.1 - 0.061 13.6 0.6 0.17 12.2 0.1 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4061) SWIM PF04434.17 RJW68990.1 - 0.069 12.8 0.7 0.12 12.0 0.1 1.7 2 0 0 2 2 2 0 SWIM zinc finger XendoU PF09412.10 RJW68992.1 - 2.1e-70 237.0 0.7 2.5e-70 236.7 0.7 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU Ribosomal_L22e PF01776.17 RJW68992.1 - 0.0069 16.7 0.6 0.15 12.5 0.2 2.4 1 1 1 2 2 2 1 Ribosomal L22e protein family DUF5036 PF16439.5 RJW68992.1 - 0.048 13.4 0.1 0.11 12.2 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5036) Clc-like PF07062.12 RJW68999.1 - 0.12 11.9 6.9 0.27 10.7 0.0 2.5 1 1 1 2 2 2 0 Clc-like PMEI PF04043.15 RJW68999.1 - 0.15 12.4 1.1 0.29 11.5 0.1 1.9 2 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor PMP22_Claudin PF00822.20 RJW68999.1 - 0.16 11.8 7.0 0.81 9.5 7.0 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF1759 PF03564.15 RJW69000.1 - 0.0036 17.2 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) 7tm_1 PF00001.21 RJW69001.1 - 1.4e-06 27.8 10.5 0.0013 18.1 1.5 3.0 3 0 0 3 3 3 2 7 transmembrane receptor (rhodopsin family) LMBR1 PF04791.16 RJW69001.1 - 0.0033 16.4 0.1 0.0033 16.4 0.1 2.1 3 0 0 3 3 3 1 LMBR1-like membrane protein VitD-bind_III PF09164.10 RJW69001.1 - 0.043 13.8 1.1 0.11 12.5 1.1 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DUF1030 PF06270.11 RJW69001.1 - 0.072 12.9 0.8 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1030) GWT1 PF06423.12 RJW69001.1 - 0.072 13.2 3.0 0.18 11.9 0.1 2.8 3 0 0 3 3 3 0 GWT1 DHHC PF01529.20 RJW69001.1 - 3.3 7.8 11.0 2 8.5 3.7 3.1 3 1 0 3 3 3 0 DHHC palmitoyltransferase PDZ PF00595.24 RJW69003.1 - 3.1e-42 142.8 0.1 6.6e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RJW69003.1 - 4.6e-20 71.2 2.0 1.1e-10 41.1 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 RJW69003.1 - 3.5e-10 40.1 0.1 0.00012 22.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 RJW69003.1 - 0.021 14.8 0.2 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Tricorn protease PDZ domain Mucin PF01456.17 RJW69003.1 - 0.033 14.2 0.1 0.033 14.2 0.1 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Peptidase_M16_C PF05193.21 RJW69004.1 - 7e-35 120.7 0.0 1.8e-34 119.3 0.0 1.8 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RJW69004.1 - 1.9e-06 27.9 5.6 3.9e-06 26.9 0.0 3.5 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) AAA_3 PF07726.11 RJW69004.1 - 0.058 13.3 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DapB_C PF05173.14 RJW69005.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DUF5329 PF17263.2 RJW69006.1 - 0.6 10.3 2.8 9.8 6.4 0.1 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5329) Eaf7 PF07904.13 RJW69007.1 - 5.3e-17 62.1 0.5 7.9e-17 61.6 0.5 1.6 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Snf7 PF03357.21 RJW69008.1 - 2.2e-31 108.8 5.3 2.2e-31 108.8 5.3 1.3 2 0 0 2 2 2 1 Snf7 OKR_DC_1_C PF03711.15 RJW69008.1 - 0.041 14.2 0.1 0.09 13.1 0.1 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain DUF2250 PF10007.9 RJW69008.1 - 0.095 12.8 1.1 3.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DASH_Dam1 PF08653.10 RJW69008.1 - 0.21 11.4 1.5 0.39 10.6 0.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 Cytochrom_B562 PF07361.11 RJW69008.1 - 4.9 7.9 12.0 0.9 10.2 0.3 3.1 3 0 0 3 3 3 0 Cytochrome b562 Glyco_transf_43 PF03360.16 RJW69010.1 - 2.5e-65 220.1 0.0 3.1e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 PknG_rubred PF16919.5 RJW69011.1 - 0.012 15.7 0.4 0.037 14.2 0.1 1.8 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain Peptidase_M22 PF00814.25 RJW69012.1 - 1.2e-86 290.8 0.0 1.8e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family XPG_I_2 PF12813.7 RJW69012.1 - 2.8e-07 30.3 0.0 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 RJW69012.1 - 7e-05 23.2 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RJW69012.1 - 0.0055 17.0 0.1 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 XPG I-region ERCC4 PF02732.15 RJW69014.1 - 3.2e-11 43.7 0.0 5.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain BCS1_N PF08740.11 RJW69015.1 - 2.1e-40 138.7 0.6 3.6e-40 138.0 0.6 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 RJW69015.1 - 2e-20 73.5 0.0 4e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 RJW69015.1 - 0.00091 18.9 0.0 0.0029 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RJW69015.1 - 0.0014 19.1 0.0 0.0036 17.7 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 RJW69015.1 - 0.0014 18.6 0.0 0.0082 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 RJW69015.1 - 0.0034 17.8 0.0 0.0079 16.6 0.0 1.6 2 0 0 2 2 1 1 RNA helicase AAA_7 PF12775.7 RJW69015.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 RJW69015.1 - 0.035 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 RJW69015.1 - 0.05 13.4 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 RJW69015.1 - 0.058 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 RJW69015.1 - 0.059 12.7 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 RJW69015.1 - 0.067 13.7 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RJW69015.1 - 0.067 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RJW69015.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RJW69015.1 - 0.12 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 RJW69015.1 - 0.15 12.4 0.0 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 RJW69015.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 RJW69016.1 - 1.6e-40 138.6 0.0 5.1e-40 137.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW69016.1 - 1.1e-08 34.7 0.1 2.5e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RJW69016.1 - 7e-05 23.1 0.1 0.0058 16.9 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 RJW69016.1 - 0.00016 21.7 0.0 0.00079 19.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RJW69016.1 - 0.00021 21.5 0.0 0.0006 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RJW69016.1 - 0.00057 20.3 0.1 0.025 15.0 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 RJW69016.1 - 0.0015 17.8 0.0 0.0034 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 RJW69016.1 - 0.006 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 RJW69016.1 - 0.0062 17.1 0.0 0.046 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RJW69016.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RJW69016.1 - 0.018 14.5 0.0 0.054 13.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 RJW69016.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RJW69016.1 - 0.064 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 RJW69016.1 - 0.066 12.9 0.1 0.67 9.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RJW69016.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 RJW69016.1 - 0.076 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 RJW69016.1 - 0.081 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 RJW69016.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RJW69016.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain RNA_helicase PF00910.22 RJW69016.1 - 0.16 12.3 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 RJW69016.1 - 0.18 11.5 0.0 0.47 10.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain EMC3_TMCO1 PF01956.16 RJW69017.1 - 1.1e-46 158.7 0.0 1.7e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Anillin PF08174.11 RJW69019.1 - 2.5e-16 60.4 0.0 2.9e-14 53.7 0.0 2.5 2 0 0 2 2 2 1 Cell division protein anillin HR1 PF02185.16 RJW69019.1 - 0.023 14.8 1.3 0.05 13.7 1.3 1.6 1 0 0 1 1 1 0 Hr1 repeat RolB_RolC PF02027.17 RJW69019.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family DJ-1_PfpI PF01965.24 RJW69020.1 - 0.00033 20.5 0.0 0.00074 19.4 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family IF3_C PF00707.22 RJW69023.1 - 0.00057 19.8 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Ion_trans PF00520.31 RJW69024.1 - 0.031 13.5 2.0 0.04 13.2 0.3 1.8 2 0 0 2 2 2 0 Ion transport protein HSP70 PF00012.20 RJW69025.1 - 9.2e-08 30.7 0.0 1.7e-06 26.6 0.0 3.8 3 2 1 4 4 4 2 Hsp70 protein HLH PF00010.26 RJW69028.1 - 2.8e-08 33.6 0.0 5.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TF_Zn_Ribbon PF08271.12 RJW69029.1 - 0.061 12.8 1.0 0.11 12.0 0.2 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding TROVE PF05731.11 RJW69032.1 - 3.8e-57 194.3 0.2 6.4e-57 193.6 0.2 1.3 1 0 0 1 1 1 1 TROVE domain DUF4062 PF13271.6 RJW69032.1 - 2.9e-23 82.0 0.0 1.2e-22 80.1 0.0 2.2 2 0 0 2 2 1 1 Domain of unknown function (DUF4062) WD40 PF00400.32 RJW69032.1 - 2.4e-15 56.7 17.7 0.0085 16.9 0.2 11.0 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW69032.1 - 1.8e-07 31.3 0.0 3.8 7.9 0.0 6.4 6 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 RJW69032.1 - 1.4e-05 25.1 0.3 0.065 13.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 RJW69032.1 - 0.0049 17.3 0.0 0.039 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 RJW69032.1 - 0.012 16.1 0.0 0.053 14.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PRK PF00485.18 RJW69032.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 RJW69032.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain DUF1133 PF06576.11 RJW69032.1 - 0.017 14.5 0.2 0.68 9.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1133) APAF1_C PF17908.1 RJW69032.1 - 0.021 14.8 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 APAF-1 helical domain AAA_22 PF13401.6 RJW69032.1 - 0.037 14.3 0.1 1 9.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain RAB3GAP2_N PF14655.6 RJW69032.1 - 0.058 12.7 0.1 3 7.0 0.0 3.2 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_29 PF13555.6 RJW69032.1 - 0.12 12.2 0.2 0.33 10.7 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 RJW69032.1 - 0.2 11.2 0.3 0.6 9.7 0.3 1.7 1 0 0 1 1 1 0 AAA domain TTL PF03133.15 RJW69033.1 - 2.8e-80 269.6 0.2 3.5e-80 269.3 0.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RJW69033.1 - 6.9e-08 32.0 0.0 0.00088 18.6 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RJW69033.1 - 1.2e-05 24.7 0.0 0.0085 15.4 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 RJW69033.1 - 0.03 13.9 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain zf-rbx1 PF12678.7 RJW69037.1 - 0.0018 18.5 10.1 0.5 10.7 10.1 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RJW69037.1 - 0.0056 16.7 7.8 0.014 15.4 5.8 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FAM194 PF14977.6 RJW69038.1 - 1e-06 28.2 0.2 0.013 14.8 0.1 2.4 2 0 0 2 2 2 2 FAM194 protein Pam16 PF03656.13 RJW69039.1 - 1.1e-15 57.7 0.0 1.1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Pam16 CLZ PF16526.5 RJW69040.1 - 3.1e-24 85.1 6.1 7.3e-24 83.9 6.1 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 RJW69040.1 - 1.4e-20 73.2 0.0 2.5e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RJW69040.1 - 5.3e-17 61.9 4.0 7.9e-17 61.3 4.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW69040.1 - 0.063 13.3 1.8 0.19 11.7 1.8 1.8 1 0 0 1 1 1 0 Ion channel SRF-TF PF00319.18 RJW69041.1 - 8.4e-11 41.2 0.2 2e-10 40.0 0.2 1.7 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MAM33 PF02330.16 RJW69042.1 - 0.00031 20.7 0.4 0.00048 20.1 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein COesterase PF00135.28 RJW69043.1 - 3e-25 89.1 0.9 2.7e-24 85.9 0.9 2.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RJW69043.1 - 0.0057 16.5 0.1 0.08 12.8 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold IBN_N PF03810.19 RJW69044.1 - 5.3e-06 26.3 0.0 1.5e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_C PF08767.11 RJW69044.1 - 0.0065 15.7 3.0 0.0082 15.4 0.4 2.4 3 0 0 3 3 3 1 CRM1 C terminal SUIM_assoc PF16619.5 RJW69045.1 - 0.024 14.7 2.7 0.024 14.7 2.7 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PH_RBD PF12068.8 RJW69046.1 - 1.3e-08 34.5 0.2 1.2e-07 31.3 0.0 2.5 2 1 0 2 2 2 1 Rab-binding domain (RBD) Homeodomain PF00046.29 RJW69049.1 - 6.2e-11 42.0 1.0 1.2e-10 41.0 1.0 1.5 1 0 0 1 1 1 1 Homeodomain Ion_trans PF00520.31 RJW69052.1 - 6.8e-16 58.2 15.6 6.8e-16 58.2 15.6 2.1 2 1 0 2 2 2 1 Ion transport protein TRP_2 PF08344.11 RJW69052.1 - 1.5e-15 57.1 0.8 3.6e-15 55.9 0.8 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II DUF5318 PF17249.2 RJW69052.1 - 0.077 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5318) PKD_channel PF08016.12 RJW69052.1 - 2.9 6.5 19.5 0.24 10.0 2.8 3.0 3 0 0 3 3 3 0 Polycystin cation channel LRR_9 PF14580.6 RJW69054.1 - 4e-15 55.8 7.3 1.4e-14 53.9 6.9 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 RJW69054.1 - 1.1e-13 51.1 26.8 7.3e-07 29.4 6.5 4.2 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW69054.1 - 6e-10 38.7 52.5 5.3e-06 26.1 10.4 3.9 2 1 4 6 6 6 5 Leucine rich repeat MA3 PF02847.17 RJW69054.1 - 0.077 13.0 1.3 0.31 11.0 0.2 2.5 2 0 0 2 2 2 0 MA3 domain UvrB_inter PF17757.1 RJW69054.1 - 0.35 11.1 4.4 3.5 7.9 0.1 3.9 3 1 1 4 4 4 0 UvrB interaction domain DUF3069 PF11269.8 RJW69054.1 - 3.6 7.9 7.7 8 6.7 0.1 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3069) LRR_1 PF00560.33 RJW69054.1 - 9.2 7.3 12.7 91 4.2 1.0 5.3 4 1 0 4 4 4 0 Leucine Rich Repeat HAD_2 PF13419.6 RJW69055.1 - 2.6e-17 63.5 0.0 4.1e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RJW69055.1 - 1.5e-15 58.0 0.0 2e-13 51.1 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RJW69055.1 - 6.9e-07 29.2 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 RJW69055.1 - 0.081 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.19 RJW69056.1 - 1.2e-86 290.8 0.0 2.1e-86 290.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RJW69056.1 - 4.3e-33 114.9 0.1 2.1e-31 109.4 0.1 2.3 1 1 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 RJW69056.1 - 0.039 13.0 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 RJW69056.1 - 0.085 13.1 0.1 0.38 11.0 0.1 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RJW69056.1 - 0.11 11.6 0.1 13 4.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Mito_carr PF00153.27 RJW69057.1 - 7e-38 128.5 0.7 9e-20 70.4 0.1 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein IBR PF01485.21 RJW69058.1 - 7.4e-11 42.1 37.6 1.1e-06 28.7 6.1 4.5 5 1 0 5 5 5 2 IBR domain, a half RING-finger domain LRR19-TM PF15176.6 RJW69058.1 - 0.24 11.4 0.0 0.24 11.4 0.0 2.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain FYVE PF01363.21 RJW69058.1 - 0.37 11.0 25.7 0.26 11.5 4.3 3.1 2 1 0 2 2 2 0 FYVE zinc finger zf-RING_UBOX PF13445.6 RJW69058.1 - 0.89 9.6 26.8 0.6 10.2 6.3 3.8 4 0 0 4 4 4 0 RING-type zinc-finger zf-C3HC4 PF00097.25 RJW69058.1 - 1.3 9.0 29.8 0.86 9.5 8.0 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW69058.1 - 1.6 9.1 29.6 1.3 9.4 8.4 3.5 3 0 0 3 3 3 0 Ring finger domain Vma12 PF11712.8 RJW69059.1 - 0.14 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Nic96 PF04097.14 RJW69061.1 - 7.2e-126 421.1 0.0 1.3e-125 420.3 0.0 1.4 1 1 0 1 1 1 1 Nup93/Nic96 Nup84_Nup100 PF04121.13 RJW69061.1 - 0.0071 14.5 0.0 0.014 13.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Acyl-CoA_dh_2 PF08028.11 RJW69061.1 - 0.018 15.3 0.1 0.86 9.9 0.0 3.0 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain TPR_14 PF13428.6 RJW69061.1 - 0.043 14.6 0.1 17 6.6 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 RJW69062.1 - 3.2e-11 43.7 1.6 6.1e-06 26.7 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW69062.1 - 3.6e-08 33.0 2.8 0.0028 18.0 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 RJW69062.1 - 4.1e-08 33.6 1.3 0.00029 21.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW69062.1 - 6.1e-06 26.4 0.1 0.21 12.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RJW69062.1 - 2.4e-05 24.5 3.5 0.001 19.4 0.1 3.7 3 1 0 3 3 3 1 Ankyrin repeat Na_K-ATPase PF00287.18 RJW69063.1 - 6.6e-41 140.3 1.0 8.7e-41 139.9 1.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain MPS-4 PF17523.2 RJW69063.1 - 0.26 11.5 3.6 0.16 12.1 0.6 2.2 3 0 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Ax_dynein_light PF10211.9 RJW69064.1 - 2.9e-63 213.2 3.7 3.7e-63 212.9 3.7 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain BST2 PF16716.5 RJW69064.1 - 0.032 14.8 0.7 0.032 14.8 0.7 2.4 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 ADIP PF11559.8 RJW69064.1 - 0.46 10.6 11.5 0.36 10.9 8.7 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sin_N PF04801.13 RJW69065.1 - 1.7e-42 146.2 0.0 4.4e-42 144.8 0.0 1.7 1 1 0 1 1 1 1 Sin-like protein conserved region Tcf25 PF04910.14 RJW69066.1 - 4.6e-99 331.8 0.0 5.8e-99 331.5 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Homeodomain PF00046.29 RJW69069.1 - 2.3e-21 75.4 7.8 4.4e-21 74.5 7.8 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW69069.1 - 0.012 15.5 0.4 0.047 13.6 0.4 2.1 1 0 0 1 1 1 0 Homeobox KN domain YokU PF14122.6 RJW69073.1 - 0.025 14.6 0.1 0.059 13.4 0.0 1.5 2 0 0 2 2 2 0 YokU-like protein, putative antitoxin Ank_4 PF13637.6 RJW69076.1 - 7e-43 144.5 4.3 5.9e-14 52.2 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW69076.1 - 1.5e-41 140.8 5.6 6.6e-15 55.5 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RJW69076.1 - 2.9e-40 135.0 9.9 4.2e-08 33.3 0.1 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 RJW69076.1 - 2.8e-34 116.7 8.6 1.3e-10 41.3 0.1 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW69076.1 - 2e-32 107.5 5.3 6.4e-06 26.1 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Cyclin_N PF00134.23 RJW69077.1 - 4.3e-07 29.7 0.1 0.00081 19.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Mito_carr PF00153.27 RJW69079.1 - 2.1e-45 152.6 1.7 5e-19 68.0 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 RJW69080.1 - 5.4e-05 23.6 0.2 5.4e-05 23.6 0.2 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW69080.1 - 8.8e-05 22.1 0.5 0.66 10.1 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RJW69080.1 - 0.0013 18.1 0.4 0.15 11.7 0.0 2.8 2 0 0 2 2 2 1 EF hand Spc7 PF08317.11 RJW69080.1 - 0.015 14.2 16.7 0.025 13.5 4.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein EF-hand_8 PF13833.6 RJW69080.1 - 0.017 15.0 1.5 0.87 9.5 0.1 3.2 2 1 1 3 3 3 0 EF-hand domain pair DUF1857 PF08982.11 RJW69080.1 - 0.046 13.6 1.8 0.093 12.6 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) DUF763 PF05559.11 RJW69080.1 - 0.15 11.2 2.2 0.34 10.0 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF763) PARP_reg PF02877.14 RJW69080.1 - 0.17 12.0 4.4 0.24 11.5 0.6 2.5 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain DUF4407 PF14362.6 RJW69080.1 - 2.2 7.5 10.4 5.1 6.4 10.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 RJW69080.1 - 7.8 7.1 15.8 0.34 11.5 7.5 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal 7tm_1 PF00001.21 RJW69081.1 - 1.7e-09 37.4 1.5 3.4e-09 36.4 1.5 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW69081.1 - 0.0055 16.1 0.7 0.044 13.2 0.7 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Phage_holin_5_2 PF16079.5 RJW69081.1 - 0.035 14.4 0.3 0.68 10.3 0.0 2.4 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V 7tm_4 PF13853.6 RJW69081.1 - 0.26 11.0 2.4 0.31 10.8 1.2 1.7 1 1 1 2 2 2 0 Olfactory receptor DSPc PF00782.20 RJW69082.1 - 1.2e-15 57.4 0.1 1.9e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain HLH PF00010.26 RJW69084.1 - 0.039 13.9 0.0 0.13 12.2 0.0 2.0 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain ERM PF00769.19 RJW69084.1 - 0.079 12.8 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family tRNA_int_end_N2 PF12928.7 RJW69085.1 - 6.7e-07 29.4 0.0 1.6e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term Thump_like PF18096.1 RJW69085.1 - 0.049 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 THUMP domain-like tRNA_int_endo_N PF02778.14 RJW69085.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Adaptin_N PF01602.20 RJW69087.1 - 1.7e-119 399.8 8.0 2.6e-119 399.2 8.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RJW69087.1 - 1.4e-05 25.2 1.4 0.00015 21.8 0.0 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RJW69087.1 - 0.00027 21.3 0.5 0.0037 17.6 0.1 3.1 3 0 0 3 3 3 1 HEAT repeats PCI PF01399.27 RJW69089.1 - 2.6e-07 31.1 1.5 2.6e-07 31.1 1.5 3.4 3 1 1 4 4 4 1 PCI domain Hus1 PF04005.12 RJW69090.1 - 1.1e-51 175.7 0.0 1.1e-50 172.4 0.0 2.4 2 1 0 2 2 2 1 Hus1-like protein BRCT PF00533.26 RJW69090.1 - 1.7e-10 41.1 0.1 0.00011 22.5 0.0 3.2 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 RJW69090.1 - 4.3e-09 36.2 0.9 1.2e-07 31.5 0.0 3.4 3 1 0 3 3 3 1 twin BRCT domain BRCT_2 PF16589.5 RJW69090.1 - 1.8e-05 25.1 0.0 0.002 18.5 0.0 3.2 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 RJW69090.1 - 3e-05 24.2 0.2 0.021 15.1 0.0 3.2 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain Rad1 PF02144.16 RJW69090.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 DUF3408 PF11888.8 RJW69090.1 - 0.2 11.8 1.7 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF4888 PF16229.5 RJW69092.1 - 0.24 11.4 0.1 0.33 10.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4888) BBP1_C PF15272.6 RJW69093.1 - 0.029 14.2 0.5 0.029 14.2 0.5 3.0 2 1 1 3 3 3 0 Spindle pole body component BBP1, C-terminal AAA_23 PF13476.6 RJW69093.1 - 0.94 9.9 8.9 0.99 9.9 5.7 2.4 2 0 0 2 2 2 0 AAA domain Tropomyosin_1 PF12718.7 RJW69093.1 - 1.2 9.3 24.0 7.8 6.7 18.7 3.5 2 1 0 2 2 2 0 Tropomyosin like DUF4795 PF16043.5 RJW69093.1 - 1.6 8.3 14.3 1.1 8.8 10.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) TPR_MLP1_2 PF07926.12 RJW69093.1 - 3.1 7.9 24.0 0.71 9.9 8.7 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein RGS PF00615.19 RJW69096.1 - 1.4e-28 99.6 0.8 2.3e-28 98.8 0.8 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3509 PF12021.8 RJW69097.1 - 0.0039 16.9 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) MCM PF00493.23 RJW69098.1 - 5.6e-59 198.9 0.0 9.5e-59 198.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RJW69098.1 - 4.2e-17 62.2 0.8 9.6e-17 61.0 0.8 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RJW69098.1 - 4.8e-15 55.7 0.0 1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 RJW69098.1 - 9.1e-06 25.2 0.1 0.011 15.2 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RJW69098.1 - 5.5e-05 23.2 0.0 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RJW69098.1 - 0.00096 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW69098.1 - 0.022 15.2 0.1 0.077 13.4 0.1 2.0 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 RJW69098.1 - 0.034 13.9 0.0 0.38 10.4 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain A2L_zn_ribbon PF08792.10 RJW69098.1 - 0.085 12.6 0.1 0.28 11.0 0.1 1.9 1 0 0 1 1 1 0 A2L zinc ribbon domain AAA_7 PF12775.7 RJW69098.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF169 PF02596.15 RJW69100.1 - 0.011 15.7 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 WD40 PF00400.32 RJW69101.1 - 1.1e-40 136.8 39.2 2.3e-07 31.4 0.2 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW69101.1 - 1.8e-20 73.0 3.7 0.0022 18.2 0.1 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW69101.1 - 2.2e-08 33.5 0.7 0.21 10.5 0.0 4.9 3 2 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 RJW69101.1 - 0.0047 16.3 3.3 0.23 10.7 3.3 2.9 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Pkinase PF00069.25 RJW69102.1 - 4.7e-69 232.7 0.0 1.2e-68 231.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69102.1 - 1.5e-35 122.8 0.0 2.8e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 RJW69102.1 - 5.1e-09 35.6 5.9 0.038 14.2 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 RJW69102.1 - 1.2e-05 25.6 2.9 0.00016 22.0 0.8 3.5 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 RJW69102.1 - 2.3e-05 24.8 0.4 2.3e-05 24.8 0.4 4.6 5 0 0 5 5 5 1 HEAT-like repeat Pkinase_fungal PF17667.1 RJW69102.1 - 0.00019 20.3 0.0 0.00044 19.2 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW69102.1 - 0.0047 16.3 0.0 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RJW69102.1 - 0.015 15.3 2.5 0.025 14.5 0.0 2.7 4 0 0 4 4 4 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW69102.1 - 0.015 14.3 0.0 0.035 13.1 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Arm PF00514.23 RJW69102.1 - 0.015 15.3 13.6 0.19 11.8 0.1 5.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4042 PF13251.6 RJW69102.1 - 0.05 13.3 1.2 0.88 9.3 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) RIO1 PF01163.22 RJW69102.1 - 0.3 10.7 1.0 10 5.6 0.3 2.3 1 1 1 2 2 2 0 RIO1 family DUF953 PF06110.11 RJW69103.1 - 7.7e-36 122.3 0.2 1.9e-27 95.2 0.1 2.2 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF953) Rap1a PF18602.1 RJW69103.1 - 0.0013 19.0 0.0 0.36 11.2 0.0 2.8 3 0 0 3 3 3 2 Rap1a immunity proteins Thioredoxin_9 PF14595.6 RJW69103.1 - 0.32 10.8 3.0 1.2 8.9 0.2 2.4 1 1 1 2 2 2 0 Thioredoxin PFK PF00365.20 RJW69104.1 - 2.4e-200 663.7 1.2 2.6e-109 365.0 0.7 2.1 2 0 0 2 2 2 2 Phosphofructokinase Ank_2 PF12796.7 RJW69105.1 - 8.6e-105 343.5 28.4 3.7e-14 53.1 0.0 9.3 1 1 8 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW69105.1 - 9.1e-103 335.4 55.8 1.8e-13 50.7 0.4 12.0 3 3 12 15 15 15 15 Ankyrin repeats (many copies) Ank PF00023.30 RJW69105.1 - 3.4e-95 308.7 54.6 8.8e-07 29.1 0.2 16.4 16 0 0 16 16 16 15 Ankyrin repeat Ank_5 PF13857.6 RJW69105.1 - 1.1e-88 290.1 32.7 1.6e-12 47.4 0.0 13.0 3 3 9 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW69105.1 - 1e-80 256.0 32.2 2.8e-05 24.2 0.0 16.7 17 0 0 17 17 17 15 Ankyrin repeat Peptidase_M18 PF02127.15 RJW69106.1 - 2.7e-57 194.5 0.0 3.6e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) HTH_psq PF05225.16 RJW69106.1 - 2.4e-06 27.1 0.0 5.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF3425 PF11905.8 RJW69107.1 - 0.042 13.8 1.0 0.65 10.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3425) ScsC_N PF18312.1 RJW69107.1 - 0.064 13.1 0.2 1.8 8.4 0.2 2.3 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain TES PF08034.11 RJW69109.1 - 1.5e-25 89.2 17.9 1.5e-25 89.2 17.9 5.5 3 2 1 4 4 4 2 Trematode eggshell synthesis protein PRR20 PF15708.5 RJW69109.1 - 0.21 11.5 0.5 0.44 10.4 0.5 1.4 1 0 0 1 1 1 0 Proline-rich protein family 20 DUF3386 PF11866.8 RJW69113.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) Anoctamin PF04547.12 RJW69115.1 - 1.6e-121 406.3 7.8 1.9e-121 406.1 7.8 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Ribosomal_L1 PF00687.21 RJW69116.1 - 1.9e-26 93.1 0.0 3.3e-26 92.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family BRCT PF00533.26 RJW69117.1 - 1.4e-06 28.5 0.0 6.2e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RJW69117.1 - 0.0019 18.6 0.0 0.022 15.1 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RJW69117.1 - 0.0097 15.8 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PSK_trans_fac PF07704.11 RJW69117.1 - 0.49 11.2 3.2 2.6 8.9 1.0 2.5 2 0 0 2 2 2 0 Rv0623-like transcription factor CCDC24 PF15669.5 RJW69117.1 - 0.52 10.2 3.7 0.26 11.2 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family LIM PF00412.22 RJW69119.1 - 5e-11 42.6 4.7 1.3e-10 41.3 4.7 1.8 1 0 0 1 1 1 1 LIM domain WD40 PF00400.32 RJW69120.1 - 7.3e-07 29.8 4.2 0.38 11.7 0.0 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW69120.1 - 3.2e-05 24.1 0.0 0.39 11.1 0.0 4.7 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5122 PF17164.4 RJW69120.1 - 0.39 11.0 1.1 14 6.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller 7tm_1 PF00001.21 RJW69121.1 - 0.00019 20.8 0.2 0.00032 20.1 0.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW69121.1 - 0.029 13.6 5.6 0.085 12.1 1.3 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Yip1 PF04893.17 RJW69122.1 - 1.1e-12 48.0 14.6 1.1e-12 48.0 14.6 1.9 1 1 1 2 2 2 1 Yip1 domain Alpha_adaptin_C PF02296.16 RJW69123.1 - 4.9e-36 123.4 0.0 9.5e-36 122.4 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 RJW69123.1 - 1.5e-15 57.5 0.3 9.5e-15 54.9 0.3 2.3 1 1 0 1 1 1 1 Adaptin C-terminal domain Adaptin_N PF01602.20 RJW69123.1 - 1.7e-15 56.6 0.0 2.3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Hexapep PF00132.24 RJW69124.1 - 1.2e-11 43.8 9.4 4.6e-08 32.5 2.4 3.3 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RJW69124.1 - 2.9e-09 36.5 3.4 2.3e-06 27.3 1.2 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.23 RJW69124.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase DUF4954 PF16314.5 RJW69124.1 - 0.026 12.7 0.5 0.061 11.5 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 RJW69124.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.3 1 1 0 1 1 1 0 L-fucokinase WD40_3 PF15911.5 RJW69125.1 - 7.7e-19 67.4 0.1 3e-18 65.5 0.1 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat Clathrin PF00637.20 RJW69125.1 - 8.1e-11 42.0 4.1 0.0047 16.8 0.1 5.3 2 1 3 5 5 5 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 RJW69125.1 - 4.2e-10 39.3 6.1 0.0013 17.9 0.0 5.0 4 1 1 5 5 5 2 Coatomer WD associated region ANAPC4_WD40 PF12894.7 RJW69125.1 - 3.2e-07 30.5 0.2 0.034 14.5 0.1 4.6 3 1 2 5 5 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_7 PF13176.6 RJW69125.1 - 0.0014 18.5 9.6 8.6 6.6 0.6 7.8 7 2 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW69125.1 - 0.0018 18.5 18.0 1.7 9.0 0.4 7.1 7 2 0 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RJW69125.1 - 0.0072 17.1 31.8 2.2 9.3 2.8 9.6 9 1 3 12 12 9 1 Tetratricopeptide repeat WD40_like PF17005.5 RJW69125.1 - 0.0078 15.6 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain DZR PF12773.7 RJW69125.1 - 0.0086 16.1 4.6 0.019 15.0 4.6 1.6 1 0 0 1 1 1 1 Double zinc ribbon TPR_2 PF07719.17 RJW69125.1 - 0.0089 16.1 30.8 9.3 6.7 0.2 9.8 12 0 0 12 12 9 1 Tetratricopeptide repeat eIF2A PF08662.11 RJW69125.1 - 0.012 15.5 0.1 0.048 13.5 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A TPR_1 PF00515.28 RJW69125.1 - 0.016 15.0 21.9 0.84 9.6 0.0 8.0 8 1 0 8 8 8 0 Tetratricopeptide repeat PD40 PF07676.12 RJW69125.1 - 0.029 14.3 0.0 0.69 9.9 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 RJW69125.1 - 0.049 14.5 2.3 62 4.7 0.1 5.1 5 0 0 5 5 4 0 WD domain, G-beta repeat TPR_8 PF13181.6 RJW69125.1 - 0.41 11.0 12.6 9.3 6.7 0.3 6.6 6 1 1 7 7 6 0 Tetratricopeptide repeat DUF410 PF04190.13 RJW69125.1 - 1.1 9.1 3.8 1 9.1 0.1 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF410) TPR_19 PF14559.6 RJW69125.1 - 1.4 9.5 22.4 30 5.2 0.1 7.2 6 2 2 8 8 8 0 Tetratricopeptide repeat SNAP PF14938.6 RJW69125.1 - 1.4 8.3 11.4 0.17 11.3 5.8 2.3 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 RJW69125.1 - 3.5 8.5 13.0 20 6.1 0.2 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat OapA_N PF08525.11 RJW69126.1 - 0.17 11.9 0.8 0.41 10.6 0.1 2.1 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif ST7 PF04184.12 RJW69127.1 - 2.7e-254 844.6 3.6 3.4e-254 844.3 3.6 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 RJW69127.1 - 1.7e-06 28.3 1.9 0.00057 20.3 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW69127.1 - 2.2e-05 24.9 5.3 3.9 8.5 0.1 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW69127.1 - 4.4e-05 23.9 6.7 0.00013 22.4 2.3 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Clathrin PF00637.20 RJW69127.1 - 0.00046 20.1 1.7 0.0011 18.8 1.1 1.9 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_16 PF13432.6 RJW69127.1 - 0.00051 20.6 1.4 0.11 13.2 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Sld7_C PF18596.1 RJW69127.1 - 0.13 12.4 0.4 0.32 11.2 0.4 1.6 1 0 0 1 1 1 0 Sld7 C-terminal domain TPR_2 PF07719.17 RJW69127.1 - 0.19 11.9 0.0 0.19 11.9 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 RJW69127.1 - 0.19 12.0 6.7 12 6.2 0.8 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW69127.1 - 0.77 9.7 7.6 4 7.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW69127.1 - 5.6 7.3 9.6 24 5.2 7.6 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 KTI12 PF08433.10 RJW69128.1 - 1.2e-19 70.9 0.7 5.4e-14 52.3 2.6 2.1 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_33 PF13671.6 RJW69128.1 - 2.3e-09 37.6 0.0 4.8e-08 33.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RJW69128.1 - 2.2e-05 24.9 0.0 5.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 RJW69128.1 - 0.00015 22.3 0.1 0.023 15.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RJW69128.1 - 0.015 15.3 0.9 0.087 12.9 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Methyltransf_7 PF03492.15 RJW69128.1 - 0.018 14.3 0.4 0.028 13.6 0.4 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase 6PF2K PF01591.18 RJW69128.1 - 0.044 13.1 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RVT_1 PF00078.27 RJW69129.1 - 4.2e-05 23.2 0.1 0.00014 21.5 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TAN PF11640.8 RJW69129.1 - 0.04 14.0 0.6 0.31 11.2 0.0 2.6 2 1 2 4 4 4 0 Telomere-length maintenance and DNA damage repair AAA_2 PF07724.14 RJW69130.1 - 1.1e-40 139.6 0.0 1.8e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 RJW69130.1 - 4.9e-13 49.6 0.0 9.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 RJW69130.1 - 2.1e-12 46.9 0.1 4.7e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 RJW69130.1 - 3.3e-06 27.1 0.0 7.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RJW69130.1 - 6.8e-05 22.3 0.2 0.04 13.3 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 RJW69130.1 - 0.00011 21.9 0.0 0.00093 18.9 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 RJW69130.1 - 0.00012 22.4 0.2 0.00064 20.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RJW69130.1 - 0.00046 20.2 0.0 0.00085 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RJW69130.1 - 0.0017 17.9 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 RJW69130.1 - 0.0055 16.5 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 RJW69130.1 - 0.0059 16.4 0.0 0.042 13.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RJW69130.1 - 0.0067 16.8 0.0 0.026 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 RJW69130.1 - 0.014 15.3 0.2 0.058 13.3 0.2 2.1 1 1 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 RJW69130.1 - 0.017 15.2 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 RJW69130.1 - 0.021 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 RJW69130.1 - 0.057 13.2 0.1 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 RJW69130.1 - 0.066 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 RJW69130.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 RJW69130.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Kinase-PPPase PF03618.14 RJW69130.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase/pyrophosphorylase MCM PF00493.23 RJW69130.1 - 0.18 10.8 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain NPR2 PF06218.11 RJW69130.1 - 0.19 10.5 0.0 0.39 9.4 0.0 1.4 1 0 0 1 1 1 0 Nitrogen permease regulator 2 PhoH PF02562.16 RJW69130.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein zf-ISL3 PF14690.6 RJW69131.1 - 0.023 15.4 0.4 1.3 9.7 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Beta-Casp PF10996.8 RJW69132.1 - 4e-22 78.6 0.0 1.1e-21 77.2 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 RJW69132.1 - 1.6e-19 70.1 0.0 3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 RJW69132.1 - 6.2e-19 67.7 0.0 1.1e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 RJW69132.1 - 2.6e-09 36.9 0.2 3.2e-08 33.4 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RJW69132.1 - 4.7e-08 33.3 0.3 0.00033 20.7 0.1 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 RJW69132.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 RJW69132.1 - 0.13 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family KH_1 PF00013.29 RJW69133.1 - 2.3e-33 113.8 4.0 1.3e-17 63.3 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 RJW69133.1 - 5.2e-10 39.0 0.1 0.00047 19.9 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 RJW69133.1 - 8.9e-05 22.3 0.2 0.13 12.1 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 RJW69133.1 - 0.00013 21.9 1.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 2 NusA-like KH domain SNF2_N PF00176.23 RJW69134.1 - 1.2e-49 168.9 0.5 4.4e-49 167.1 0.5 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW69134.1 - 5e-13 49.4 0.0 5.9e-12 45.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW69134.1 - 1.2e-08 35.1 0.0 0.00084 19.4 0.0 2.6 1 1 0 2 2 2 2 Type III restriction enzyme, res subunit PAAR_motif PF05488.13 RJW69135.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 PAAR motif Oxidored_q6 PF01058.22 RJW69136.1 - 4.7e-23 81.4 0.1 6.1e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit ZU5 PF00791.20 RJW69138.1 - 2.2e-31 108.1 0.1 3.2e-28 97.9 0.0 2.2 2 0 0 2 2 2 2 ZU5 domain MBD PF01429.19 RJW69140.1 - 0.0029 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain Ig_3 PF13927.6 RJW69142.1 - 2.4e-27 95.4 6.3 2.1e-10 41.1 0.4 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RJW69142.1 - 2.4e-21 75.6 3.7 6.8e-08 32.5 0.1 4.1 4 1 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW69142.1 - 1.6e-20 73.2 9.1 1.3e-06 28.7 0.2 4.2 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RJW69142.1 - 2.6e-19 69.4 1.8 2.2e-06 27.8 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.25 RJW69142.1 - 1.7e-16 60.2 8.0 3e-06 27.3 0.5 4.1 3 1 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 RJW69142.1 - 0.0024 17.4 0.0 0.73 9.4 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain PapC_C PF13953.6 RJW69142.1 - 0.11 12.4 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 PapC C-terminal domain VirE2 PF07229.12 RJW69143.1 - 0.064 11.9 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 VirE2 CcdA PF07362.12 RJW69143.1 - 0.088 13.2 0.4 0.2 12.1 0.4 1.5 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA MRP-S32 PF10210.9 RJW69144.1 - 2.9e-10 40.6 0.0 8.7e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S32 VHL PF01847.16 RJW69145.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 VHL beta domain DDE_Tnp_IS1595 PF12762.7 RJW69147.1 - 1.2e-11 44.9 0.6 2.4e-11 43.9 0.1 1.7 2 0 0 2 2 2 1 ISXO2-like transposase domain CBM46 PF18448.1 RJW69147.1 - 0.0016 18.7 0.3 0.0038 17.5 0.1 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain SLC3A2_N PF16028.5 RJW69149.1 - 3.3e-23 81.0 0.3 6.1e-23 80.2 0.3 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Alpha-amylase PF00128.24 RJW69149.1 - 1.5e-15 57.6 0.2 3e-12 46.8 0.2 2.6 2 1 0 2 2 2 2 Alpha amylase, catalytic domain DUF1323 PF07037.11 RJW69152.1 - 0.071 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) bZIP_1 PF00170.21 RJW69154.1 - 1.1e-11 44.6 9.5 2.6e-11 43.4 9.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RJW69154.1 - 8.5e-07 29.0 11.7 1.7e-06 28.0 11.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RJW69154.1 - 0.0036 17.8 8.4 0.0067 16.9 8.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Tho2 PF11262.8 RJW69154.1 - 0.22 10.7 1.4 0.35 10.0 1.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RVT_1 PF00078.27 RJW69155.1 - 2.9e-45 154.5 0.0 5e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW69155.1 - 1.2e-05 25.2 0.0 3.3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW69155.1 - 9.7e-05 22.0 0.6 0.00021 20.9 0.6 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thioredoxin PF00085.20 RJW69157.1 - 1.9e-12 47.1 0.0 3.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HCV_NS2 PF01538.18 RJW69157.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 DUF4483 PF14825.6 RJW69159.1 - 2.7e-26 92.2 0.0 3.7e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Alg6_Alg8 PF03155.15 RJW69160.1 - 5.6e-136 454.3 29.0 7.1e-136 454.0 29.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ets PF00178.22 RJW69161.1 - 8.2e-19 67.9 1.7 3.3e-16 59.5 0.1 2.9 3 0 0 3 3 3 2 Ets-domain Homeodomain PF00046.29 RJW69162.1 - 3.4e-19 68.5 6.0 3.4e-19 68.5 6.0 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RJW69162.1 - 0.024 14.5 0.1 0.058 13.3 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF4757 PF15949.5 RJW69163.1 - 0.00088 19.8 9.0 0.0024 18.4 9.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4757) CH PF00307.31 RJW69163.1 - 0.0037 17.4 0.0 0.0077 16.4 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain PDZ PF00595.24 RJW69163.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 RJW69163.1 - 0.069 13.0 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 PDZ domain ODV-E18 PF10717.9 RJW69165.1 - 0.027 14.3 2.1 0.041 13.8 2.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 SP_C-Propep PF08999.10 RJW69165.1 - 0.052 13.3 0.3 0.084 12.7 0.3 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF3827 PF12877.7 RJW69165.1 - 0.31 9.4 0.5 0.32 9.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Sigma_reg_N PF13800.6 RJW69165.1 - 0.32 11.3 6.5 0.47 10.8 6.5 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal CK_II_beta PF01214.18 RJW69166.1 - 1.4e-35 122.7 0.1 9.1e-21 74.5 0.1 2.1 1 1 1 2 2 2 2 Casein kinase II regulatory subunit SPEG_u2 PF16650.5 RJW69166.1 - 0.04 14.1 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Unstructured region on SPEG complex protein RVT_1 PF00078.27 RJW69167.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.5 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_7 PF13499.6 RJW69168.1 - 2e-06 28.2 0.2 3.3e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW69168.1 - 0.00052 19.7 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 RJW69168.1 - 0.0012 18.3 0.2 0.0042 16.5 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 RJW69168.1 - 0.0052 16.6 0.6 0.34 10.8 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair RasGAP PF00616.19 RJW69169.1 - 1.9e-22 80.0 0.0 5.1e-22 78.6 0.0 1.8 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 RJW69169.1 - 8.4e-21 74.6 0.0 1.9e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 RJW69169.1 - 0.0035 17.3 0.2 0.043 13.7 0.0 3.1 5 0 0 5 5 5 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 RJW69169.1 - 0.071 10.7 4.7 0.27 8.8 0.1 2.4 2 1 0 3 3 3 0 Cell morphogenesis central region Phage_holin_3_6 PF07332.11 RJW69171.1 - 4.6 7.3 6.3 8.6 6.4 6.3 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5090 PF17009.5 RJW69171.1 - 7.9 6.4 9.3 16 5.4 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Nucleo_P87 PF07267.11 RJW69172.1 - 0.039 12.8 11.3 0.041 12.8 11.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 RJW69172.1 - 0.3 9.3 23.1 0.36 9.1 23.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 RJW69172.1 - 0.37 9.3 27.1 0.48 9.0 27.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rtf2 PF04641.12 RJW69172.1 - 0.8 9.0 16.9 1.4 8.3 16.9 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Macoilin PF09726.9 RJW69172.1 - 0.87 8.1 15.8 0.86 8.1 15.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF4776 PF16003.5 RJW69172.1 - 1.8 7.5 18.2 2 7.3 18.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Neur_chan_memb PF02932.16 RJW69172.1 - 3.5 7.6 8.6 3.7 7.5 8.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.9 RJW69172.1 - 4.7 6.7 46.1 3.5 7.2 43.9 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EF-hand_6 PF13405.6 RJW69173.1 - 1.3e-08 34.1 1.3 0.0001 21.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RJW69173.1 - 6.8e-05 22.1 3.6 0.00027 20.3 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 RJW69173.1 - 0.00024 21.5 0.7 0.0057 17.1 0.0 2.4 2 1 1 3 3 3 1 EF-hand domain pair LRR_8 PF13855.6 RJW69174.1 - 2.7e-15 55.9 11.9 3e-14 52.5 1.6 4.0 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 RJW69174.1 - 8.6e-08 32.4 11.2 0.00022 21.5 0.4 4.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW69174.1 - 0.0003 20.9 7.5 2.8 8.8 0.0 6.9 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_5 PF13306.6 RJW69174.1 - 0.00038 20.4 0.0 0.00087 19.2 0.0 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) I-set PF07679.16 RJW69174.1 - 0.0013 18.7 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW69174.1 - 0.0031 18.1 0.0 0.012 16.2 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RJW69174.1 - 0.027 14.8 0.0 0.08 13.3 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain LRRCT PF01463.24 RJW69174.1 - 0.051 14.1 0.0 0.22 12.1 0.0 2.3 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain RVT_1 PF00078.27 RJW69176.1 - 0.0051 16.4 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M24 PF00557.24 RJW69178.1 - 5.4e-30 104.6 0.0 9e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RJW69178.1 - 7.8e-26 90.2 0.0 1.6e-25 89.2 0.0 1.5 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF1134 PF06577.12 RJW69178.1 - 0.21 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) zf-C2H2_4 PF13894.6 RJW69180.1 - 3.4e-07 30.5 29.3 0.00057 20.5 0.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW69180.1 - 0.00012 22.3 0.5 0.00012 22.3 0.5 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type PyrI_C PF02748.15 RJW69180.1 - 0.0036 17.2 7.0 0.36 10.8 0.1 2.8 3 0 0 3 3 3 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 RJW69180.1 - 0.014 15.4 1.2 0.014 15.4 1.2 3.3 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_2 PF13465.6 RJW69180.1 - 0.052 14.0 17.7 22 5.7 0.1 4.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 RJW69180.1 - 0.25 11.7 18.9 0.91 9.9 0.7 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 RJW69180.1 - 0.46 10.7 13.4 18 5.6 0.1 3.8 2 1 0 2 2 2 0 AN1-like Zinc finger CpXC PF14353.6 RJW69180.1 - 1.7 8.7 8.8 31 4.6 8.8 2.5 1 1 0 1 1 1 0 CpXC protein zf-C2H2_jaz PF12171.8 RJW69180.1 - 5.9 7.3 13.5 1.9 8.9 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Med11 PF10280.9 RJW69182.1 - 0.18 12.2 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Mediator complex protein TPR_2 PF07719.17 RJW69183.1 - 2.4e-20 70.9 12.9 0.11 12.7 2.2 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 RJW69183.1 - 2.2e-18 66.6 9.8 1.3e-06 28.9 0.0 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 RJW69183.1 - 9.5e-18 63.6 0.1 0.00016 21.3 0.0 4.9 4 0 0 4 4 4 4 TPR repeat TPR_14 PF13428.6 RJW69183.1 - 4.5e-16 58.2 7.5 0.0068 17.1 0.0 7.7 6 3 3 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 RJW69183.1 - 2.7e-15 55.6 3.3 0.048 14.1 0.0 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 RJW69183.1 - 2.5e-11 42.9 15.3 0.38 10.7 0.0 8.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 RJW69183.1 - 1.3e-09 38.1 2.4 0.048 13.8 0.0 4.5 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 RJW69183.1 - 2.5e-07 30.9 18.0 0.38 11.1 1.1 8.1 5 1 4 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW69183.1 - 6.4e-07 29.8 10.8 0.0017 18.8 0.0 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 RJW69183.1 - 3.7e-05 23.1 1.2 0.0036 16.6 0.2 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 RJW69183.1 - 6.1e-05 23.3 0.1 0.036 14.4 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RJW69183.1 - 0.003 17.6 13.1 39 4.8 0.0 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW69183.1 - 0.0034 17.3 0.3 56 4.1 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW69183.1 - 0.025 15.2 7.8 17 6.3 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat HemY_N PF07219.13 RJW69183.1 - 0.057 13.6 0.2 0.37 11.0 0.0 2.5 2 0 0 2 2 2 0 HemY protein N-terminus ChAPs PF09295.10 RJW69183.1 - 0.08 11.9 0.1 7 5.5 0.0 2.8 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 RJW69183.1 - 0.55 10.5 9.3 1.2 9.4 0.0 4.7 3 1 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 T2SS-T3SS_pil_N PF13629.6 RJW69184.1 - 0.086 12.6 0.3 2.3 8.0 0.0 3.5 5 0 0 5 5 5 0 Pilus formation protein N terminal region PALP PF00291.25 RJW69185.1 - 1.4e-63 215.0 0.0 2.3e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 RJW69185.1 - 6.9e-05 23.2 0.0 0.00029 21.2 0.0 2.1 1 0 0 1 1 1 1 CBS domain CH PF00307.31 RJW69186.1 - 3.1e-40 136.7 0.2 6.6e-19 68.1 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain Plectin PF00681.20 RJW69186.1 - 1.1e-32 111.6 0.8 0.043 13.7 0.0 18.4 19 2 2 21 21 21 5 Plectin repeat Spectrin PF00435.21 RJW69186.1 - 4.1e-11 43.3 38.0 1.4e-07 31.9 0.5 7.4 8 0 0 8 8 8 3 Spectrin repeat CAMSAP_CH PF11971.8 RJW69186.1 - 2.5e-08 33.6 0.0 5.3e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain ABC_tran_CTD PF16326.5 RJW69186.1 - 0.02 15.1 3.0 6.9 7.0 0.4 4.3 3 1 1 4 4 4 0 ABC transporter C-terminal domain ING PF12998.7 RJW69186.1 - 0.16 12.6 2.9 0.19 12.4 0.6 2.4 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF5340 PF17275.2 RJW69186.1 - 5.4 7.2 6.8 5.6 7.2 0.3 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5340) Ion_trans PF00520.31 RJW69187.1 - 1.1e-30 106.7 8.5 1.5e-30 106.2 8.5 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW69187.1 - 5.5e-11 42.3 0.5 5.5e-11 42.3 0.5 2.2 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 RJW69187.1 - 3.3e-10 39.9 0.0 6.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_9 PF13426.7 RJW69187.1 - 6e-09 36.1 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 RJW69187.1 - 0.0025 17.8 0.0 0.0069 16.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 RJW69187.1 - 0.073 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 PAS fold RVT_1 PF00078.27 RJW69188.1 - 6.9e-05 22.5 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD PF00628.29 RJW69188.1 - 0.058 13.3 0.7 0.15 12.0 0.7 1.6 1 0 0 1 1 1 0 PHD-finger EloA-BP1 PF15870.5 RJW69189.1 - 4.7e-10 40.0 0.0 8.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 ElonginA binding-protein 1 TFIIF_alpha PF05793.12 RJW69189.1 - 0.2 10.2 1.5 0.31 9.6 1.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MCM_lid PF17855.1 RJW69190.1 - 0.00011 22.5 0.0 0.00025 21.4 0.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain DSPc PF00782.20 RJW69191.1 - 6.3e-10 39.0 0.0 7.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RJW69191.1 - 5.4e-08 33.1 0.0 6.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 RJW69191.1 - 4.4e-05 23.2 0.0 4.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RJW69191.1 - 0.02 14.9 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family SBF PF01758.16 RJW69193.1 - 1.1e-27 97.1 5.6 1.1e-27 97.1 5.6 2.2 1 1 1 2 2 2 1 Sodium Bile acid symporter family MFS_1 PF07690.16 RJW69194.1 - 1.5e-19 70.2 34.3 6.4e-10 38.5 19.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RJW69194.1 - 4.4e-05 22.2 7.0 4.4e-05 22.2 7.0 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein OATP PF03137.20 RJW69194.1 - 0.00017 20.0 0.0 0.00017 20.0 0.0 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family YhzD PF14120.6 RJW69194.1 - 0.079 13.1 0.9 0.14 12.3 0.9 1.3 1 0 0 1 1 1 0 YhzD-like protein Gate PF07670.14 RJW69194.1 - 0.2 11.9 4.4 1.1 9.5 4.4 2.5 1 1 0 1 1 1 0 Nucleoside recognition Utp11 PF03998.13 RJW69195.1 - 2.3e-06 27.7 1.7 3.9e-06 27.0 1.7 1.3 1 0 0 1 1 1 1 Utp11 protein Lzipper-MIP1 PF14389.6 RJW69195.1 - 0.03 14.6 4.0 1.7 9.0 0.1 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TolA_bind_tri PF16331.5 RJW69195.1 - 0.044 13.9 4.7 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 TolA binding protein trimerisation SAMP PF05924.11 RJW69195.1 - 0.072 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 SAMP Motif FliD_N PF02465.18 RJW69195.1 - 0.092 13.4 0.7 2.8 8.7 0.1 2.2 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3455 PF11937.8 RJW69195.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3455) SAP PF02037.27 RJW69195.1 - 0.44 10.4 3.3 3.9 7.3 0.1 2.8 2 0 0 2 2 2 0 SAP domain CH PF00307.31 RJW69196.1 - 0.0076 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain GILT PF03227.16 RJW69196.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) RSS_P20 PF11757.8 RJW69196.1 - 0.2 12.1 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain CDCA PF18484.1 RJW69197.1 - 0.054 13.4 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat HS1_rep PF02218.15 RJW69199.1 - 2.2e-52 175.0 16.9 7.1e-21 74.2 2.5 3.4 3 0 0 3 3 3 3 Repeat in HS1/Cortactin RVT_1 PF00078.27 RJW69199.1 - 1.8e-13 50.5 0.0 2.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMEM210 PF15195.6 RJW69199.1 - 0.005 17.2 0.5 13 6.2 0.0 3.3 1 1 2 3 3 3 1 TMEM210 family SPESP1 PF15754.5 RJW69199.1 - 0.14 11.3 1.3 0.24 10.6 1.3 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 PIN_6 PF17146.4 RJW69200.1 - 8.1e-28 96.8 0.2 1.3e-27 96.1 0.2 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 RJW69200.1 - 2.6e-19 69.1 0.2 4.7e-19 68.3 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF1641 PF07849.11 RJW69200.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) zf-FPG_IleRS PF06827.14 RJW69200.1 - 3.8 7.5 6.5 3.6 7.5 0.4 2.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF3509 PF12021.8 RJW69202.1 - 0.004 16.9 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) Thioredoxin PF00085.20 RJW69203.1 - 3.5e-21 75.1 0.0 8.9e-21 73.8 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 RJW69203.1 - 6.8e-06 26.5 0.0 3.3e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Calsequestrin PF01216.17 RJW69203.1 - 0.034 13.2 0.0 0.1 11.6 0.0 1.6 1 1 0 2 2 2 0 Calsequestrin Thioredoxin_8 PF13905.6 RJW69203.1 - 0.039 14.3 0.0 0.53 10.7 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 RJW69203.1 - 0.043 14.0 0.1 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_6 PF13848.6 RJW69203.1 - 0.098 12.6 0.1 16 5.4 0.0 2.5 1 1 1 2 2 2 0 Thioredoxin-like domain RhoGAP PF00620.27 RJW69204.1 - 0.0046 16.8 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 2 RhoGAP domain Bax1-I PF01027.20 RJW69205.1 - 1.8e-37 129.2 6.8 2.9e-37 128.5 6.8 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Tox-WTIP PF15654.6 RJW69205.1 - 0.1 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif Pkinase_Tyr PF07714.17 RJW69209.1 - 1.3e-90 303.2 0.0 1.7e-90 302.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW69209.1 - 7.5e-45 153.4 0.0 1e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RJW69209.1 - 2.3e-21 75.6 0.0 4.6e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 RJW69209.1 - 4.5e-05 22.6 0.0 6.6e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RJW69209.1 - 0.0082 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RJW69209.1 - 0.011 15.7 0.0 0.15 11.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 RJW69209.1 - 0.026 14.1 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 RJW69210.1 - 2.1e-46 158.4 0.0 3.1e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69210.1 - 7.3e-22 77.9 0.0 1.5e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW69210.1 - 0.006 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RJW69210.1 - 0.032 13.0 0.0 0.078 11.7 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 RJW69213.1 - 0.00075 20.3 0.0 1.9 9.5 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW69213.1 - 0.001 19.3 0.0 0.11 12.8 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Phlebovirus_G2 PF07245.11 RJW69213.1 - 0.068 11.7 0.2 0.13 10.7 0.2 1.4 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Hum_adeno_E3A PF05393.11 RJW69214.1 - 0.041 13.9 0.5 0.044 13.8 0.5 1.1 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Ntox24 PF15529.6 RJW69215.1 - 0.034 14.5 0.1 0.08 13.3 0.1 1.6 2 0 0 2 2 2 0 Bacterial toxin 24 DUF3206 PF11472.8 RJW69215.1 - 0.034 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) VEGF_C PF14554.6 RJW69215.1 - 0.087 12.9 0.0 0.98 9.6 0.0 2.2 2 0 0 2 2 2 0 VEGF heparin-binding domain PKD_channel PF08016.12 RJW69216.1 - 2.9e-16 59.2 6.6 4e-16 58.7 6.6 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RJW69216.1 - 3e-10 39.8 10.6 4.4e-10 39.2 10.6 1.1 1 0 0 1 1 1 1 Ion transport protein Glyoxalase_4 PF13669.6 RJW69218.1 - 0.094 13.0 0.1 0.3 11.4 0.1 1.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIX PF00778.17 RJW69219.1 - 1.8e-30 104.6 0.0 2.9e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 DIX domain Axin_b-cat_bind PF08833.10 RJW69219.1 - 1.1e-12 47.8 0.0 7.4e-12 45.2 0.0 2.6 1 0 0 1 1 1 1 Axin beta-catenin binding domain EB1 PF03271.17 RJW69220.1 - 1.9e-08 34.4 1.0 3.9e-08 33.4 1.0 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif Zf_RING PF16744.5 RJW69221.1 - 0.07 13.2 2.2 0.13 12.3 0.2 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger SH3_1 PF00018.28 RJW69222.1 - 7.1e-12 44.7 0.0 1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RJW69222.1 - 8.2e-12 44.8 0.0 1.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RJW69222.1 - 1.4e-08 34.3 0.0 2.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4207 PF13904.6 RJW69223.1 - 2.7e-14 53.5 25.9 4.5e-14 52.7 25.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) F-box-like PF12937.7 RJW69224.1 - 7.5e-13 48.2 1.6 7.5e-13 48.2 1.6 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RJW69224.1 - 1.3e-05 24.9 2.6 5.9e-05 22.8 2.6 2.1 1 1 0 1 1 1 1 F-box domain UMPH-1 PF05822.12 RJW69225.1 - 8.3e-77 258.0 0.0 1e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) SID-1_RNA_chan PF13965.6 RJW69229.1 - 1.6e-207 690.7 0.1 2.7e-207 690.0 0.1 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Ceramidase PF05875.12 RJW69229.1 - 0.0003 20.3 20.9 0.079 12.4 20.9 2.4 1 1 0 1 1 1 1 Ceramidase DUF836 PF05768.14 RJW69230.1 - 8.3e-12 45.4 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 RJW69230.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 RJW69230.1 - 0.085 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.24 RJW69230.1 - 0.13 12.5 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin RDD PF06271.12 RJW69231.1 - 3.2e-09 37.1 5.5 1.6e-07 31.6 5.5 2.9 1 1 0 1 1 1 1 RDD family PAS_3 PF08447.12 RJW69232.1 - 0.0051 17.1 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold UQ_con PF00179.26 RJW69233.1 - 6.2e-43 145.8 0.1 8.4e-43 145.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RJW69233.1 - 0.0018 18.0 0.0 0.01 15.6 0.0 2.3 1 1 0 1 1 1 1 Prokaryotic E2 family B UPF0149 PF03695.13 RJW69234.1 - 0.034 14.4 0.0 0.043 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) IL5 PF02025.15 RJW69234.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 1 0 1 1 1 0 Interleukin 5 Asp PF00026.23 RJW69235.1 - 2e-14 53.7 0.0 1.8e-12 47.3 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW69235.1 - 0.086 12.6 0.0 0.41 10.4 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Glyco_hydro_19 PF00182.19 RJW69236.1 - 1.9e-22 80.3 0.4 5.9e-22 78.7 0.4 1.8 1 1 0 1 1 1 1 Chitinase class I PRCC PF10253.9 RJW69236.1 - 8.2 7.2 9.3 12 6.7 9.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ASC PF00858.24 RJW69238.1 - 9.2e-70 235.8 5.7 1.3e-69 235.3 5.7 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel fn3 PF00041.21 RJW69239.1 - 1.5e-19 70.1 1.8 2.1e-14 53.6 0.1 3.0 3 0 0 3 3 3 2 Fibronectin type III domain Ephrin_lbd PF01404.19 RJW69239.1 - 3.3e-09 37.1 0.6 6.5e-07 29.6 0.0 2.6 1 1 0 2 2 2 1 Ephrin receptor ligand binding domain Ephrin_rec_like PF07699.13 RJW69239.1 - 2e-06 27.4 12.0 3.7e-06 26.6 6.1 3.2 2 1 1 3 3 3 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 RJW69239.1 - 3e-05 24.5 5.0 0.00016 22.2 0.2 3.7 3 2 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain FXa_inhibition PF14670.6 RJW69239.1 - 0.0032 17.7 12.0 0.012 15.8 1.2 3.1 1 1 2 3 3 3 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RJW69239.1 - 0.014 15.3 6.2 0.12 12.4 0.6 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like DUF2369 PF10179.9 RJW69239.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 RJW69239.1 - 0.024 14.8 0.9 0.35 11.0 0.1 2.8 2 1 0 2 2 2 0 Fibronectin type III domain PhoD_N PF16655.5 RJW69239.1 - 0.053 14.1 0.0 0.26 11.9 0.0 2.2 2 1 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain EGF_3 PF12947.7 RJW69239.1 - 0.12 12.6 4.8 5.3 7.3 0.2 2.7 2 0 0 2 2 2 0 EGF domain EGF PF00008.27 RJW69239.1 - 0.57 10.5 4.6 16 5.9 0.9 2.8 2 0 0 2 2 2 0 EGF-like domain La PF05383.17 RJW69240.1 - 0.001 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 La domain Pkinase_Tyr PF07714.17 RJW69241.1 - 0.0028 17.0 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW69241.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Thymidylat_synt PF00303.19 RJW69242.1 - 1.6e-107 358.6 0.0 1.8e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase RT_RNaseH PF17917.1 RJW69243.1 - 6.6e-32 109.9 0.0 1.6e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW69243.1 - 9.1e-22 77.0 0.0 1.6e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF525 PF04379.14 RJW69243.1 - 2.6e-09 37.2 0.1 5.2e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.11 RJW69243.1 - 1.3e-07 32.0 0.0 2.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Phage-MuB_C PF09077.11 RJW69244.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Mu B transposition protein, C terminal His_Phos_2 PF00328.22 RJW69245.1 - 5e-18 65.6 2.3 5.5e-15 55.6 2.3 3.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ig_3 PF13927.6 RJW69247.1 - 3.1e-13 50.1 0.0 1.2e-12 48.2 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RJW69247.1 - 1.9e-09 37.4 0.0 3.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW69247.1 - 2.5e-07 30.9 0.0 1.2e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RJW69247.1 - 2.4e-06 27.6 0.0 6.6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RJW69247.1 - 0.00097 19.3 0.1 0.21 11.8 0.1 2.5 1 1 1 2 2 2 2 Immunoglobulin V-set domain Asp PF00026.23 RJW69248.1 - 2.3e-40 139.0 0.0 2.6e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW69248.1 - 5.2e-07 30.1 0.1 7.2e-06 26.4 0.0 2.1 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Glyco_hydro_125 PF06824.11 RJW69248.1 - 0.089 11.7 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) Glyco_transf_7N PF13733.6 RJW69249.1 - 2.2e-43 147.1 0.0 3.6e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RJW69249.1 - 1.4e-25 88.7 0.9 3.3e-25 87.5 0.9 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RJW69249.1 - 0.087 12.3 0.3 0.3 10.5 0.1 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Thioredoxin PF00085.20 RJW69250.1 - 1.9e-26 92.0 0.0 2.7e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RJW69250.1 - 8.7e-05 22.9 0.4 0.00099 19.5 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RJW69250.1 - 0.0002 21.6 0.0 0.0087 16.4 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 RJW69250.1 - 0.0011 18.4 0.1 0.0013 18.2 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 RJW69250.1 - 0.0025 17.6 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 RJW69250.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 RJW69250.1 - 0.076 12.8 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein KaiB PF07689.12 RJW69250.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiB domain Phosducin PF02114.16 RJW69250.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosducin HyaE PF07449.11 RJW69250.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Ribosomal_S21e PF01249.18 RJW69251.1 - 3.2e-26 91.2 0.0 5.4e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S21e RVT_1 PF00078.27 RJW69251.1 - 0.023 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) LIM PF00412.22 RJW69252.1 - 8.2e-19 67.6 14.6 2.2e-10 40.6 0.8 3.9 4 0 0 4 4 4 3 LIM domain DZR PF12773.7 RJW69252.1 - 1.2 9.2 15.7 6.7 6.8 5.3 3.5 1 1 2 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 RJW69252.1 - 5.6 6.8 11.2 10 6.0 0.1 4.2 3 1 2 5 5 5 0 zinc-ribbon domain MutS_V PF00488.21 RJW69253.1 - 3e-72 242.6 0.0 5.8e-72 241.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RJW69253.1 - 1.2e-33 117.0 2.6 2.1e-33 116.2 2.6 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 RJW69253.1 - 1.2e-16 60.8 1.4 3e-16 59.5 1.4 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 RJW69253.1 - 8.2e-12 45.6 0.0 1.9e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.20 RJW69253.1 - 4.9e-10 39.6 0.1 1.2e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 MutS domain I DUF2507 PF10702.9 RJW69254.1 - 0.069 13.1 0.0 0.094 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) bZIP_1 PF00170.21 RJW69255.1 - 0.0088 16.1 2.7 0.019 15.0 2.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RJW69255.1 - 0.015 15.3 6.1 0.022 14.8 2.7 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Ribosomal_L7Ae PF01248.26 RJW69258.1 - 1e-20 73.3 0.0 1.2e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 RJW69258.1 - 0.037 14.1 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-C2H2 PF00096.26 RJW69259.1 - 5e-18 64.5 38.8 0.00026 21.3 0.1 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW69259.1 - 1.3e-12 47.4 36.4 0.0057 17.4 0.1 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW69259.1 - 6.2e-11 42.3 13.9 0.0066 16.7 0.0 5.4 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RJW69259.1 - 9.7e-11 41.6 35.2 3.9e-06 27.0 0.0 5.9 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW69259.1 - 2e-06 27.7 29.3 0.04 13.9 0.3 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HE PF16278.5 RJW69259.1 - 0.00017 22.0 19.8 0.35 11.4 0.6 5.4 2 1 3 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 RJW69259.1 - 0.0018 18.6 29.6 0.45 11.0 0.1 5.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 RJW69259.1 - 0.76 9.7 6.4 3.8 7.5 0.2 3.8 3 1 1 4 4 4 0 LYAR-type C2HC zinc finger Ta0938 PF11494.8 RJW69259.1 - 3.8 7.8 5.3 19 5.6 0.3 2.7 1 1 1 2 2 2 0 Ta0938 zf-C2H2_2 PF12756.7 RJW69259.1 - 4.9 7.5 21.2 0.61 10.4 0.2 5.1 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) CH PF00307.31 RJW69260.1 - 8.3e-24 83.9 0.1 1.3e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 RJW69260.1 - 1.4e-10 40.6 4.6 2.2e-10 39.9 4.6 1.3 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.8 RJW69260.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain CDC24 PF06395.11 RJW69260.1 - 0.049 13.9 0.3 0.092 13.0 0.3 1.4 1 0 0 1 1 1 0 CDC24 Calponin FSIP1 PF15554.6 RJW69262.1 - 4.1e-09 36.0 18.9 0.00013 21.2 1.3 3.8 4 0 0 4 4 4 3 FSIP1 family Pro-kuma_activ PF09286.11 RJW69262.1 - 0.074 13.3 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain Ank_2 PF12796.7 RJW69264.1 - 2.1e-64 214.1 17.6 1.5e-14 54.3 0.5 6.7 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW69264.1 - 6.9e-49 163.6 3.9 1.1e-07 32.3 0.0 10.7 7 3 3 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW69264.1 - 1.5e-36 120.2 3.1 0.011 16.1 0.0 13.4 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 RJW69264.1 - 1.4e-35 120.9 13.5 0.00014 22.1 0.0 11.3 3 3 9 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 RJW69264.1 - 7.6e-33 111.5 11.2 0.012 16.1 0.0 12.3 14 0 0 14 14 14 7 Ankyrin repeat Ion_trans PF00520.31 RJW69264.1 - 6.2e-08 32.2 17.8 1.2e-07 31.2 17.8 1.5 1 1 0 1 1 1 1 Ion transport protein NPCC PF08058.11 RJW69264.1 - 0.055 13.5 5.2 4.1 7.5 1.5 2.8 2 0 0 2 2 2 0 Nuclear pore complex component zf-RING_2 PF13639.6 RJW69265.1 - 1.1e-11 44.9 7.3 2.2e-11 43.9 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RJW69265.1 - 7.4e-10 38.4 2.8 1.6e-09 37.3 2.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 RJW69265.1 - 4.8e-07 30.0 7.3 1.3e-06 28.6 7.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RJW69265.1 - 4.9e-07 29.5 7.6 9.1e-07 28.6 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW69265.1 - 6.7e-07 29.2 3.3 1.2e-06 28.3 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RJW69265.1 - 8.3e-07 28.8 5.8 1.5e-06 27.9 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW69265.1 - 0.00019 21.4 5.4 0.00041 20.3 5.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RJW69265.1 - 0.00092 19.0 3.8 0.0016 18.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RJW69265.1 - 0.0032 17.3 4.0 0.0062 16.4 4.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RJW69265.1 - 0.0032 17.5 2.0 0.009 16.0 2.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CrgA PF06781.12 RJW69265.1 - 0.0074 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Cell division protein CrgA PspB PF06667.12 RJW69265.1 - 0.014 15.4 0.4 0.029 14.4 0.4 1.5 1 0 0 1 1 1 0 Phage shock protein B RINGv PF12906.7 RJW69265.1 - 1.1 9.5 5.6 3.1 8.0 4.5 2.2 2 0 0 2 2 2 0 RING-variant domain Y_phosphatase PF00102.27 RJW69266.1 - 2.8e-68 230.0 0.0 2e-49 168.3 0.3 3.3 2 1 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 RJW69266.1 - 5.6e-24 84.3 4.8 3.2e-10 40.2 0.0 5.4 6 0 0 6 6 6 2 Fibronectin type III domain PTPlike_phytase PF14566.6 RJW69266.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate tRNA-synt_1c PF00749.21 RJW69267.1 - 4.8e-76 255.6 0.0 6.5e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain SEA PF01390.20 RJW69271.1 - 0.00034 20.6 0.1 0.00077 19.5 0.1 1.5 1 0 0 1 1 1 1 SEA domain DUF1818 PF08848.11 RJW69271.1 - 0.13 12.3 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) PurL_C PF16904.5 RJW69271.1 - 0.17 12.2 0.1 2.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus Amidohydro_1 PF01979.20 RJW69272.1 - 2e-06 27.4 0.0 6.2e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family S-AdoMet_synt_C PF02773.16 RJW69273.1 - 1.8e-67 225.6 0.0 1.9e-66 222.3 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 RJW69273.1 - 1.3e-46 157.7 0.0 2.3e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 RJW69273.1 - 2.1e-41 140.6 0.0 4.3e-41 139.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 RJW69273.1 - 0.07 11.9 0.0 0.14 10.9 0.0 1.4 1 1 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) FR47 PF08445.10 RJW69273.1 - 0.076 13.0 0.1 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Pkinase PF00069.25 RJW69274.1 - 4.4e-72 242.6 0.0 5.9e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69274.1 - 5.8e-42 143.8 0.0 8.3e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Plk4_PB2 PF18409.1 RJW69274.1 - 7.9e-29 100.5 0.0 3.8e-28 98.3 0.0 2.2 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 2 Plk4_PB1 PF18190.1 RJW69274.1 - 2.4e-24 85.6 2.1 3.6e-20 72.1 0.8 3.7 2 1 0 2 2 2 1 Polo-like Kinase 4 Polo Box 1 POLO_box PF00659.18 RJW69274.1 - 1.2e-07 31.8 0.0 7.9e-07 29.2 0.0 2.4 3 0 0 3 3 3 1 POLO box duplicated region Pkinase_fungal PF17667.1 RJW69274.1 - 7.4e-05 21.7 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW69274.1 - 9.3e-05 21.9 0.0 0.00033 20.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RJW69274.1 - 0.0014 18.6 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 RJW69274.1 - 0.062 12.9 0.3 0.44 10.1 0.1 2.2 2 1 0 2 2 2 0 RIO1 family DUF4520 PF15016.6 RJW69274.1 - 0.072 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) ANAPC3 PF12895.7 RJW69275.1 - 0.0029 17.8 0.1 0.0078 16.4 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.32 RJW69277.1 - 2.4e-20 72.5 14.7 0.00061 20.6 0.8 9.1 9 1 0 9 9 9 4 WD domain, G-beta repeat RVT_1 PF00078.27 RJW69278.1 - 9.8e-32 110.3 0.0 2.3e-31 109.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kinesin PF00225.23 RJW69280.1 - 1.1e-65 221.7 2.5 1.1e-65 221.7 2.5 2.2 2 1 1 3 3 3 1 Kinesin motor domain Methyltrn_RNA_2 PF04013.12 RJW69280.1 - 1.6 8.4 4.7 4.7 6.9 2.4 2.3 2 0 0 2 2 2 0 Putative SAM-dependent RNA methyltransferase Kinesin_assoc PF16183.5 RJW69280.1 - 2 8.5 19.6 0.86 9.7 13.9 2.8 2 1 1 3 3 3 0 Kinesin-associated Asp_protease_2 PF13650.6 RJW69281.1 - 7.2e-06 26.6 0.0 1.3e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW69281.1 - 0.006 17.1 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 RJW69281.1 - 0.033 14.5 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Myosin_tail_1 PF01576.19 RJW69283.1 - 1e-46 159.4 166.9 1.3e-46 159.1 166.9 1.1 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 RJW69283.1 - 1.4e-08 34.7 155.3 0.0015 18.1 44.3 6.1 1 1 4 5 5 5 4 Intermediate filament protein ATG16 PF08614.11 RJW69283.1 - 0.00017 21.9 182.1 0.06 13.6 11.3 8.8 1 1 5 7 7 7 3 Autophagy protein 16 (ATG16) FH2 PF02181.23 RJW69283.1 - 0.0028 16.8 8.1 0.0028 16.8 8.1 6.9 1 1 4 7 7 7 1 Formin Homology 2 Domain Lebercilin PF15619.6 RJW69283.1 - 0.003 17.2 39.3 0.003 17.2 39.3 7.6 2 2 6 8 8 6 2 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 RJW69283.1 - 0.0035 17.4 4.1 0.0035 17.4 4.1 9.3 2 2 8 10 10 8 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup54 PF13874.6 RJW69283.1 - 0.0078 16.3 16.5 0.0078 16.3 16.5 8.6 1 1 6 7 7 5 1 Nucleoporin complex subunit 54 SKA2 PF16740.5 RJW69283.1 - 0.011 15.5 12.0 0.011 15.5 12.0 9.3 1 1 9 10 10 9 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 RJW69283.1 - 0.24 11.5 94.2 0.036 14.1 6.7 10.1 2 2 10 12 12 12 0 Protein of unknown function (DUF1664) Pallilysin PF18663.1 RJW69283.1 - 0.61 10.1 4.2 2.4 8.2 0.2 3.1 3 0 0 3 3 3 0 Pallilysin beta barrel domain Laminin_II PF06009.12 RJW69283.1 - 2.1 8.4 107.2 0.21 11.6 13.1 9.5 2 1 6 10 10 10 0 Laminin Domain II Spc7 PF08317.11 RJW69283.1 - 8.4 5.2 161.9 0.65 8.8 19.1 7.9 1 1 5 7 7 7 0 Spc7 kinetochore protein DUF3708 PF12501.8 RJW69284.1 - 0.02 14.7 2.2 0.047 13.5 2.2 1.6 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Urm1 PF09138.11 RJW69284.1 - 0.07 13.5 1.0 0.15 12.4 1.0 1.5 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) ALMT PF11744.8 RJW69284.1 - 1.7 7.4 14.0 2.6 6.8 14.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 RJW69284.1 - 3.3 7.7 9.0 6 6.8 9.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1664 PF07889.12 RJW69284.1 - 6.2 6.9 17.0 11 6.0 8.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3106 PF11304.8 RJW69284.1 - 8.9 6.8 28.6 0.87 10.1 19.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) Lipase_GDSL_2 PF13472.6 RJW69286.1 - 6.1e-11 43.0 0.0 9.2e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RJW69286.1 - 2e-05 24.7 0.0 5.1e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PH PF00169.29 RJW69287.1 - 1.4e-07 32.0 0.0 5.9e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 PH domain C2 PF00168.30 RJW69287.1 - 1.4e-05 25.3 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain Ribosomal_S8e PF01201.22 RJW69288.1 - 2.9e-32 111.7 2.4 1.1e-31 109.9 2.4 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e DnaJ PF00226.31 RJW69289.1 - 5.6e-19 68.0 0.9 1.6e-18 66.5 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 RJW69289.1 - 3e-12 46.5 2.5 1.4e-09 38.0 1.4 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW69289.1 - 4.6e-08 33.2 3.6 2.6e-05 24.5 1.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RJW69289.1 - 1.2e-06 28.7 0.6 0.09 13.1 0.0 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 RJW69289.1 - 0.0034 18.1 1.0 0.97 10.5 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW69289.1 - 0.31 11.6 2.6 7.1 7.3 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-RING_2 PF13639.6 RJW69291.1 - 7.1e-11 42.3 8.6 1.8e-10 41.0 8.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RJW69291.1 - 1.5e-08 34.2 5.5 1.5e-08 34.2 5.5 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RJW69291.1 - 9.9e-07 28.7 4.4 3.3e-06 27.0 4.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RJW69291.1 - 1.3e-06 28.2 8.0 2.9e-06 27.0 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW69291.1 - 3.9e-06 26.6 8.3 7.8e-06 25.6 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW69291.1 - 2.2e-05 24.6 4.8 2.2e-05 24.6 4.8 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RJW69291.1 - 0.0013 18.6 5.6 0.0013 18.6 5.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.8 RJW69291.1 - 0.046 13.9 5.0 0.038 14.2 2.9 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 RJW69291.1 - 0.055 13.3 4.9 0.13 12.1 4.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RJW69291.1 - 0.25 11.0 5.0 0.68 9.6 5.0 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 RJW69291.1 - 0.26 11.2 9.5 0.1 12.5 5.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 RJW69291.1 - 2.1 8.5 7.7 6.5 7.0 7.7 1.9 1 0 0 1 1 1 0 RING-variant domain Cornichon PF03311.14 RJW69292.1 - 2.2e-44 150.7 5.5 3.2e-44 150.1 5.5 1.2 1 0 0 1 1 1 1 Cornichon protein Prp19 PF08606.11 RJW69292.1 - 4.2e-33 113.2 3.0 9.4e-33 112.0 3.0 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 RJW69292.1 - 1.3e-24 85.9 6.3 7.6e-07 29.7 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW69292.1 - 6.5e-14 52.0 0.1 0.011 16.0 0.0 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 RJW69292.1 - 4.7e-08 33.1 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 RJW69292.1 - 1.7e-05 24.5 0.0 3.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit WD40_like PF17005.5 RJW69292.1 - 6.7e-05 22.4 0.0 0.44 9.8 0.1 3.2 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 RJW69292.1 - 0.00011 21.3 0.0 0.13 11.2 0.0 2.6 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cep57_MT_bd PF06657.13 RJW69292.1 - 0.0072 16.8 0.6 0.43 11.0 0.0 2.6 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 eIF2A PF08662.11 RJW69292.1 - 0.013 15.4 0.1 6.4 6.6 0.1 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RJW69292.1 - 0.031 12.9 0.0 0.39 9.3 0.0 2.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 CarboxypepD_reg PF13620.6 RJW69292.1 - 0.13 12.5 0.5 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Nbas_N PF15492.6 RJW69292.1 - 0.13 11.5 0.1 0.59 9.4 0.1 1.9 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DHHC PF01529.20 RJW69292.1 - 0.42 10.7 3.6 0.36 10.9 1.2 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase Cadherin PF00028.17 RJW69293.1 - 4.3e-36 123.2 5.0 6.1e-05 23.4 0.0 10.9 8 4 1 9 9 9 7 Cadherin domain Cadherin_3 PF16184.5 RJW69293.1 - 3.6e-06 26.9 3.7 0.015 15.2 0.0 5.8 6 0 0 6 6 6 1 Cadherin-like Cadherin_2 PF08266.12 RJW69293.1 - 0.1 12.5 1.8 18 5.2 0.1 4.0 3 0 0 3 3 3 0 Cadherin-like TMCO5 PF14992.6 RJW69294.1 - 0.018 14.6 0.2 0.026 14.1 0.2 1.2 1 0 0 1 1 1 0 TMCO5 family DUF2721 PF11026.8 RJW69294.1 - 0.036 13.9 0.3 0.063 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF5542 PF17696.1 RJW69294.1 - 0.16 12.1 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5542) PDR_assoc PF08370.11 RJW69294.1 - 0.16 11.7 0.7 0.37 10.6 0.7 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated DUF2373 PF10180.9 RJW69295.1 - 6.6e-22 77.1 0.1 6.6e-22 77.1 0.1 2.2 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2373) Fer2 PF00111.27 RJW69295.1 - 2.9e-10 39.9 0.1 6.1e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Josephin PF02099.17 RJW69295.1 - 0.072 13.2 0.7 0.12 12.4 0.7 1.3 1 0 0 1 1 1 0 Josephin DUF4543 PF15076.6 RJW69295.1 - 1.3 9.2 6.3 3.7 7.8 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4543) POP1 PF06978.11 RJW69295.1 - 3.1 7.8 13.5 1.5 8.8 11.1 1.7 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 BCAS2 PF05700.11 RJW69296.1 - 1.6e-72 243.5 2.3 2e-72 243.2 2.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Golgin_A5 PF09787.9 RJW69296.1 - 0.011 15.3 3.5 0.023 14.2 3.5 1.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF3090 PF11290.8 RJW69296.1 - 0.16 11.8 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) DUF4140 PF13600.6 RJW69296.1 - 0.19 12.2 0.8 20 5.7 0.2 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spectrin PF00435.21 RJW69296.1 - 0.2 12.1 8.4 2.5 8.6 2.8 2.3 1 1 0 2 2 2 0 Spectrin repeat MetOD2 PF18548.1 RJW69296.1 - 0.57 10.3 5.0 14 5.9 0.1 3.0 3 1 1 4 4 4 0 Metanogen output domain 2 Csm1_N PF18504.1 RJW69296.1 - 1.6 9.1 5.2 1.5 9.2 1.8 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain Sulfotransfer_4 PF17784.1 RJW69297.1 - 2.6e-50 171.2 0.0 3.1e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW69297.1 - 6.1e-07 30.0 0.4 0.0034 17.8 0.1 2.5 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 RJW69297.1 - 0.085 12.3 0.1 0.15 11.5 0.1 1.7 2 1 0 2 2 2 0 Sulfotransferase domain DUF3100 PF11299.8 RJW69301.1 - 0.016 14.6 0.0 3.4 7.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3100) Fer4_18 PF13746.6 RJW69301.1 - 0.068 13.4 2.2 0.52 10.5 0.1 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain TyeA PF09059.10 RJW69301.1 - 0.083 13.0 0.1 1.2 9.3 0.0 2.0 1 1 1 2 2 2 0 TyeA PIH1_CS PF18201.1 RJW69301.1 - 0.099 13.1 0.1 0.56 10.6 0.1 1.9 1 1 0 1 1 1 0 PIH1 CS-like domain Ubiquitin_2 PF14560.6 RJW69301.1 - 0.1 13.1 0.5 21 5.6 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Ion_trans PF00520.31 RJW69302.1 - 1.4e-41 142.3 6.5 2e-41 141.8 6.5 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RJW69302.1 - 3.1e-24 85.2 0.0 6.4e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RJW69302.1 - 1.1e-13 51.0 0.3 1.1e-13 51.0 0.3 1.9 2 0 0 2 2 2 1 Ion channel IRK PF01007.20 RJW69302.1 - 0.091 12.6 1.7 4 7.2 0.5 3.3 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Metallophos PF00149.28 RJW69303.1 - 1.4e-25 91.0 0.0 2.4e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 RJW69303.1 - 0.0063 16.0 0.0 0.019 14.5 0.0 1.9 1 0 0 1 1 1 1 EF hand IQ PF00612.27 RJW69303.1 - 0.96 9.4 5.9 0.12 12.2 0.7 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif dCMP_cyt_deam_1 PF00383.23 RJW69304.1 - 5e-26 90.5 0.0 6.5e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RJW69304.1 - 1.8e-11 43.9 0.0 2.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 RJW69304.1 - 0.019 15.1 0.2 0.038 14.1 0.2 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4_like PF18774.1 RJW69304.1 - 0.039 13.9 0.1 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase NAD1 PF18778.1 RJW69304.1 - 0.049 13.7 0.2 0.079 13.0 0.2 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 RJW69304.1 - 0.098 12.5 0.5 0.17 11.8 0.5 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC2 PF18772.1 RJW69304.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 APOBEC2 Bd3614-deam PF14439.6 RJW69304.1 - 0.14 12.3 0.7 0.34 11.0 0.7 1.9 1 1 0 1 1 1 0 Bd3614-like deaminase Plasmod_Pvs28 PF06247.11 RJW69305.1 - 0.0014 18.9 1.0 0.0018 18.5 0.9 1.5 1 1 0 1 1 1 1 Pvs28 EGF domain Cadherin_C_2 PF16492.5 RJW69305.1 - 0.0085 16.8 0.0 0.013 16.2 0.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal DUF4233 PF14017.6 RJW69305.1 - 0.018 15.4 0.2 0.021 15.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) DUF5383 PF17355.2 RJW69305.1 - 0.83 10.0 2.4 1.2 9.5 2.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) PC_rep PF01851.22 RJW69306.1 - 0.084 13.3 24.3 0.51 10.9 2.7 6.2 5 1 1 6 6 6 0 Proteasome/cyclosome repeat PX PF00787.24 RJW69307.1 - 5.5e-10 39.2 0.0 7.3e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 PX domain Pro-MCH PF05824.12 RJW69307.1 - 0.0066 16.3 0.1 0.013 15.4 0.1 1.5 1 1 0 1 1 1 1 Pro-melanin-concentrating hormone (Pro-MCH) RRM_1 PF00076.22 RJW69308.1 - 6.1e-24 83.6 0.0 2.8e-08 33.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF448 PF04296.13 RJW69308.1 - 0.051 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF448) UQ_con PF00179.26 RJW69309.1 - 1.3e-46 157.8 0.0 1.7e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RJW69309.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.5 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 RJW69309.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic E2 family B DCP1 PF06058.13 RJW69311.1 - 1.2e-33 115.5 0.0 2.4e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 RJW69311.1 - 2e-14 52.6 0.2 5e-14 51.3 0.2 1.7 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus ATP-synt PF00231.19 RJW69312.1 - 9.9e-80 268.2 2.7 1.3e-79 267.9 2.7 1.1 1 0 0 1 1 1 1 ATP synthase RVT_1 PF00078.27 RJW69312.1 - 0.0031 17.1 0.0 0.0097 15.4 0.0 1.8 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Luteo_coat PF00894.18 RJW69312.1 - 0.0057 16.6 0.2 0.018 15.0 0.2 1.8 1 1 0 1 1 1 1 Luteovirus coat protein TTL PF03133.15 RJW69313.1 - 5.3e-58 196.5 1.5 1.1e-57 195.4 1.5 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family DSL PF01414.19 RJW69313.1 - 0.38 11.1 2.6 1.1 9.5 2.6 1.8 1 0 0 1 1 1 0 Delta serrate ligand UPF0182 PF03699.13 RJW69314.1 - 3.5 5.7 9.2 3.6 5.6 9.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) TraG_N PF07916.11 RJW69314.1 - 4.8 5.9 27.1 5 5.9 27.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Laminin_G_2 PF02210.24 RJW69315.1 - 3.9e-73 244.0 11.3 2.8e-24 86.1 0.1 4.8 5 0 0 5 5 5 4 Laminin G domain Laminin_G_1 PF00054.23 RJW69315.1 - 1.1e-50 171.2 3.0 5.6e-22 78.4 0.0 5.2 5 1 0 5 5 5 4 Laminin G domain F5_F8_type_C PF00754.25 RJW69315.1 - 5.8e-23 81.4 0.1 2.1e-22 79.6 0.1 2.0 1 0 0 1 1 1 1 F5/8 type C domain Laminin_G_3 PF13385.6 RJW69315.1 - 1.9e-09 37.8 12.7 0.0019 18.3 0.2 5.3 6 0 0 6 6 6 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 RJW69315.1 - 6e-05 23.3 37.7 0.00042 20.5 6.8 3.7 3 0 0 3 3 3 2 EGF-like domain GatD_N PF18195.1 RJW69315.1 - 0.13 11.6 0.5 0.49 9.7 0.5 1.9 2 0 0 2 2 2 0 GatD N-terminal domain Ig_3 PF13927.6 RJW69319.1 - 1.2e-34 118.7 3.7 3.2e-12 46.9 0.0 5.6 4 1 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 RJW69319.1 - 5.5e-31 106.5 0.0 1.3e-11 44.4 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW69319.1 - 3e-26 91.5 2.5 4.2e-08 33.4 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 RJW69319.1 - 5.9e-24 84.0 1.8 1.9e-07 31.2 0.0 5.5 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 RJW69319.1 - 8.5e-14 51.7 0.6 4.8e-05 23.5 0.0 6.5 5 2 1 6 6 6 2 Immunoglobulin V-set domain fn3 PF00041.21 RJW69319.1 - 1.3e-08 35.1 3.1 0.43 10.9 0.0 6.5 6 1 0 6 6 6 2 Fibronectin type III domain C2-set_2 PF08205.12 RJW69319.1 - 1.1e-06 28.6 1.9 0.011 15.8 0.0 4.1 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RJW69319.1 - 1.9e-06 27.4 0.0 0.04 13.5 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 RJW69319.1 - 3.8e-05 23.7 0.0 0.076 13.1 0.0 4.2 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RJW69319.1 - 0.01 16.1 0.2 9.5 6.6 0.0 4.1 4 2 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 RJW69319.1 - 0.06 13.4 0.1 2.9 8.0 0.1 3.1 3 0 0 3 3 3 0 C17orf99 Ig domain DUF218 PF02698.17 RJW69319.1 - 0.17 11.9 0.1 0.46 10.5 0.1 1.7 1 0 0 1 1 1 0 DUF218 domain Kinesin PF00225.23 RJW69320.1 - 1.1e-39 136.4 0.0 1.5e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RJW69320.1 - 1.8e-22 79.9 0.0 2.7e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 RJW69320.1 - 0.11 11.6 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase Ig_3 PF13927.6 RJW69321.1 - 1.1e-09 38.8 0.1 0.00023 21.7 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 RJW69321.1 - 2.6e-08 33.8 0.0 1.3e-06 28.4 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW69321.1 - 2.8e-08 34.0 0.3 0.00042 20.6 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RJW69321.1 - 4.1e-07 30.2 0.0 4.2e-05 23.7 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin V-set domain ig PF00047.25 RJW69321.1 - 1.7e-06 28.1 0.0 0.003 17.7 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RJW69321.1 - 0.029 13.9 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain LIM PF00412.22 RJW69322.1 - 1.6e-25 89.1 22.9 5.8e-14 52.1 5.5 2.0 2 0 0 2 2 2 2 LIM domain SopA_C PF13979.6 RJW69322.1 - 0.0011 18.7 0.2 0.0014 18.4 0.2 1.2 1 0 0 1 1 1 1 SopA-like catalytic domain PolC_DP2 PF03833.13 RJW69322.1 - 6.4 4.5 8.7 7.2 4.3 8.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 T-box_assoc PF16176.5 RJW69324.1 - 0.00035 20.7 0.6 0.00058 20.0 0.6 1.6 1 1 0 1 1 1 1 T-box transcription factor-associated Stanniocalcin PF03298.13 RJW69324.1 - 0.084 12.2 6.1 0.61 9.4 0.3 2.9 1 1 2 3 3 3 0 Stanniocalcin family Toxin_22 PF08092.11 RJW69324.1 - 3.3 7.8 7.0 78 3.4 0.2 3.2 3 0 0 3 3 3 0 Magi peptide toxin family UQ_con PF00179.26 RJW69325.1 - 1.2e-15 57.4 0.2 2.1e-15 56.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NTF2 PF02136.20 RJW69328.1 - 1.3e-20 74.1 0.1 2.6e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Acyl_transf_3 PF01757.22 RJW69329.1 - 0.00095 18.3 20.2 0.00095 18.3 20.2 3.1 2 1 0 3 3 3 2 Acyltransferase family Mak10 PF04112.13 RJW69331.1 - 2.7e-19 69.3 2.2 5.6e-19 68.3 0.1 2.4 2 1 1 3 3 3 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Dehydrin PF00257.19 RJW69332.1 - 0.087 13.4 0.5 0.12 12.9 0.5 1.1 1 0 0 1 1 1 0 Dehydrin DUF1759 PF03564.15 RJW69333.1 - 4.1e-06 26.8 0.0 6.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF2236 PF09995.9 RJW69333.1 - 0.01 16.0 0.0 0.027 14.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) DUF3987 PF13148.6 RJW69333.1 - 0.059 12.4 0.2 0.091 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1798 PF08807.10 RJW69333.1 - 0.13 12.4 0.7 0.26 11.4 0.2 1.7 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Homeobox_KN PF05920.11 RJW69335.1 - 1.6e-15 56.7 0.5 3.5e-15 55.6 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RJW69335.1 - 9.1e-06 25.4 0.6 2.4e-05 24.1 0.6 1.8 1 0 0 1 1 1 1 Homeodomain Lentivirus_VIF PF05851.11 RJW69337.1 - 0.031 13.2 0.0 0.069 12.0 0.0 1.5 2 0 0 2 2 2 0 Lentivirus virion infectivity factor (VIF) wnt PF00110.19 RJW69339.1 - 1.7e-109 366.2 16.4 2.4e-109 365.7 16.4 1.2 1 0 0 1 1 1 1 wnt family Asp_protease_2 PF13650.6 RJW69341.1 - 0.0042 17.7 0.0 0.0095 16.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Pkinase_Tyr PF07714.17 RJW69343.1 - 2.4e-80 269.6 0.0 3.4e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW69343.1 - 6.9e-34 117.4 0.0 1.4e-21 77.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain fn3 PF00041.21 RJW69343.1 - 4.6e-05 23.7 0.6 0.038 14.3 0.1 2.8 2 0 0 2 2 2 2 Fibronectin type III domain Pkinase_fungal PF17667.1 RJW69343.1 - 0.081 11.7 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RJW69343.1 - 0.22 10.9 0.2 0.73 9.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CcmD PF04995.14 RJW69343.1 - 0.26 11.4 2.2 0.47 10.6 2.2 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) AAR2 PF05282.11 RJW69344.1 - 3e-51 174.9 0.0 3.7e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein LON_substr_bdg PF02190.16 RJW69347.1 - 4.9e-27 95.2 0.0 9.1e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 RJW69347.1 - 3e-24 85.9 0.0 1.3e-23 83.9 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Lon_C PF05362.13 RJW69347.1 - 8.6e-18 64.6 0.5 9.9e-07 28.5 0.0 3.9 4 0 0 4 4 4 3 Lon protease (S16) C-terminal proteolytic domain AAA_5 PF07728.14 RJW69347.1 - 3e-09 37.0 0.0 7.2e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RJW69347.1 - 4.6e-07 30.4 2.2 1.4e-05 25.6 0.0 3.8 4 2 1 5 5 4 1 AAA ATPase domain RuvB_N PF05496.12 RJW69347.1 - 2.5e-06 27.3 0.1 7.1e-05 22.6 0.1 2.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RJW69347.1 - 1e-05 25.7 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 RJW69347.1 - 1.2e-05 24.4 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 RJW69347.1 - 1.2e-05 25.6 0.4 0.0014 18.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 RJW69347.1 - 0.00038 20.5 0.0 0.0014 18.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RJW69347.1 - 0.00063 19.7 0.0 0.0062 16.5 0.0 2.3 1 1 0 1 1 1 1 NACHT domain AAA_23 PF13476.6 RJW69347.1 - 0.0016 18.9 0.4 0.28 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RJW69347.1 - 0.0019 18.0 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein LisH_TPL PF17814.1 RJW69347.1 - 0.0039 16.8 1.3 0.54 10.0 0.0 2.6 2 0 0 2 2 2 1 LisH-like dimerisation domain AAA_18 PF13238.6 RJW69347.1 - 0.004 17.7 0.2 0.059 13.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 RJW69347.1 - 0.0048 17.3 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 RJW69347.1 - 0.012 14.8 0.6 0.03 13.5 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 RJW69347.1 - 0.021 14.7 0.1 0.47 10.3 0.0 2.6 1 1 1 2 2 2 0 NTPase AAA_33 PF13671.6 RJW69347.1 - 0.022 14.9 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RJW69347.1 - 0.03 14.2 0.0 0.089 12.7 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase TIP49 PF06068.13 RJW69347.1 - 0.033 13.4 0.0 0.079 12.2 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain MIEAP PF16026.5 RJW69347.1 - 0.033 14.4 0.2 0.077 13.2 0.2 1.6 1 0 0 1 1 1 0 Mitochondria-eating protein TsaE PF02367.17 RJW69347.1 - 0.042 13.8 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 RJW69347.1 - 0.042 13.6 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RJW69347.1 - 0.046 13.2 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 RJW69347.1 - 0.075 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 RJW69347.1 - 0.08 13.4 0.6 2.3 8.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 RJW69347.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 RJW69347.1 - 0.11 13.1 0.3 0.82 10.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.18 RJW69347.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 RJW69347.1 - 0.18 11.8 0.6 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 RJW69347.1 - 0.21 11.4 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain TPR_14 PF13428.6 RJW69350.1 - 6e-08 32.9 0.9 2.7 9.0 0.1 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW69350.1 - 7.7e-07 29.5 1.1 0.16 12.5 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW69350.1 - 3.1e-06 26.9 1.1 0.15 12.3 0.1 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 RJW69350.1 - 6.8e-06 26.1 1.1 0.12 12.5 0.0 2.6 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 RJW69350.1 - 5.7e-05 23.3 4.8 0.075 13.3 0.5 4.4 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RJW69350.1 - 0.01 15.6 2.7 0.063 13.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 RJW69350.1 - 0.011 16.0 0.1 7.9 7.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 RJW69350.1 - 0.024 14.3 4.1 3.1 7.6 0.1 4.2 5 0 0 5 5 5 0 TPR repeat TPR_16 PF13432.6 RJW69350.1 - 0.046 14.4 1.3 27 5.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat NEMO PF11577.8 RJW69350.1 - 0.11 12.5 1.5 5.1 7.2 0.1 2.7 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO TPR_8 PF13181.6 RJW69350.1 - 0.47 10.8 4.1 13 6.3 0.0 4.4 4 2 1 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 RJW69352.1 - 4.1e-46 157.5 39.0 4.1e-46 157.5 39.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RJW69352.1 - 3.3e-06 26.3 10.2 3.3e-06 26.3 10.2 2.3 1 1 0 2 2 2 2 Sugar (and other) transporter ParcG PF10274.9 RJW69353.1 - 1.3e-30 106.9 0.0 1.6e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein MMS19_C PF12460.8 RJW69353.1 - 0.00073 18.8 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal Kinesin PF00225.23 RJW69354.1 - 0.00031 19.8 0.0 0.00097 18.2 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain CDH1_2_SANT_HL1 PF18375.1 RJW69354.1 - 0.7 10.6 10.3 1.5 9.5 2.7 2.9 1 1 2 3 3 3 0 CDH1/2 SANT-Helical linker 1 FlaC_arch PF05377.11 RJW69354.1 - 4.9 7.6 6.0 44 4.6 0.1 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Lyase_1 PF00206.20 RJW69355.1 - 3e-26 92.5 0.0 4.9e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 RJW69355.1 - 7.1e-12 45.7 0.2 1.7e-11 44.5 0.2 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF3616 PF12275.8 RJW69355.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) Inositol_P PF00459.25 RJW69356.1 - 8.4e-69 232.1 0.0 1.1e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Pmp3 PF01679.17 RJW69357.1 - 0.12 12.6 1.6 0.19 12.0 1.6 1.3 1 0 0 1 1 1 0 Proteolipid membrane potential modulator DUF4692 PF15763.5 RJW69359.1 - 0.17 12.4 0.9 0.27 11.7 0.5 1.5 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) CENP-H PF05837.12 RJW69360.1 - 0.021 15.2 0.7 0.021 15.2 0.7 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DegS PF05384.11 RJW69361.1 - 0.16 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Sensor protein DegS YcaO PF02624.16 RJW69362.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Mitoc_L55 PF09776.9 RJW69364.1 - 5.4e-07 29.3 0.1 1.6e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 MFS_1 PF07690.16 RJW69367.1 - 2.5e-44 151.7 46.1 1.1e-40 139.7 28.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RJW69367.1 - 4.5e-06 25.8 12.6 0.00067 18.6 8.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter COX8 PF02285.15 RJW69367.1 - 0.074 12.9 0.0 0.4 10.6 0.0 2.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII TssN PF17555.2 RJW69367.1 - 0.15 11.5 2.1 0.33 10.3 2.1 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssN WD40 PF00400.32 RJW69374.1 - 3.5e-22 78.3 15.7 1e-05 26.1 0.1 8.6 8 1 0 8 8 8 5 WD domain, G-beta repeat Utp12 PF04003.12 RJW69374.1 - 2.4e-08 34.2 0.7 4.7e-08 33.3 0.7 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 RJW69374.1 - 0.00078 19.7 0.1 41 4.6 0.0 5.4 2 2 3 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW69374.1 - 0.048 13.5 0.0 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 RJW69374.1 - 0.1 11.8 0.1 24 4.0 0.0 2.9 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ins_P5_2-kin PF06090.12 RJW69378.1 - 4.4e-56 190.7 0.0 5.4e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4497 PF14924.6 RJW69380.1 - 3.7e-05 24.1 0.0 0.00019 21.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) Glyco_transf_8 PF01501.20 RJW69381.1 - 2.8e-08 33.7 0.1 4.3e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 RJW69381.1 - 0.044 13.2 0.4 0.18 11.2 0.4 1.8 1 1 0 1 1 1 0 Glucosyltransferase 24 Glyco_transf_8 PF01501.20 RJW69382.1 - 5.2e-06 26.2 0.1 5.2e-06 26.2 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 8 Galactosyl_T PF01762.21 RJW69383.1 - 4.6e-54 183.2 0.0 4.8e-27 95.1 0.0 2.1 2 0 0 2 2 2 2 Galactosyltransferase Pkinase_Tyr PF07714.17 RJW69385.1 - 5.1e-89 298.0 0.0 6.6e-89 297.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW69385.1 - 2.2e-43 148.5 0.0 3.1e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RJW69385.1 - 0.012 14.5 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 RJW69385.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 RJW69385.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C2 PF00168.30 RJW69387.1 - 1.9e-28 98.8 0.3 4e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain FerI PF08151.12 RJW69387.1 - 1.2e-10 41.3 0.7 2.4e-10 40.3 0.7 1.5 1 0 0 1 1 1 1 FerI (NUC094) domain PI3K_C2 PF00792.24 RJW69387.1 - 0.12 12.3 0.1 0.78 9.6 0.0 2.1 2 1 0 2 2 2 0 Phosphoinositide 3-kinase C2 RVT_1 PF00078.27 RJW69388.1 - 2.4e-24 86.1 0.0 3.4e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DZF PF07528.14 RJW69391.1 - 1.4e-63 214.9 0.0 2.3e-63 214.1 0.0 1.4 1 0 0 1 1 1 1 DZF domain Nrap_D5 PF17406.2 RJW69391.1 - 0.071 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 RNA_pol_Rpb1_1 PF04997.12 RJW69392.1 - 1.1e-104 350.2 0.6 1.7e-104 349.5 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 RJW69392.1 - 6.7e-101 337.2 0.1 1.1e-100 336.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 RJW69392.1 - 2.8e-71 239.1 0.1 5.4e-71 238.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 RJW69392.1 - 9.5e-62 208.2 0.0 1.8e-61 207.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 RJW69392.1 - 1e-46 158.7 0.0 2e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 RJW69392.1 - 4.3e-44 149.8 1.9 9e-44 148.7 1.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 RJW69392.1 - 6.2e-37 125.9 0.4 1.9e-36 124.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Ras PF00071.22 RJW69394.1 - 8.3e-49 165.3 0.0 1e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW69394.1 - 4.3e-19 68.9 0.0 2.2e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW69394.1 - 1.6e-08 34.2 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW69394.1 - 1.3e-05 24.8 0.0 6e-05 22.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RJW69394.1 - 0.00023 21.1 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RJW69394.1 - 0.003 17.6 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 RJW69394.1 - 0.051 13.4 0.3 0.13 12.0 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 RJW69394.1 - 0.1 11.8 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CbiA PF01656.23 RJW69394.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.20 RJW69394.1 - 0.17 11.0 0.4 2.4 7.2 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit SSTK-IP PF15836.5 RJW69396.1 - 0.047 13.8 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Tmpp129 PF10272.9 RJW69397.1 - 3.9e-114 381.6 0.0 4.6e-114 381.4 0.0 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor zf-RING_2 PF13639.6 RJW69397.1 - 1.4 9.3 10.0 1.6 9.1 8.0 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RRN7 PF11781.8 RJW69397.1 - 2.3 8.0 8.1 1.1 9.1 1.2 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 HLH PF00010.26 RJW69400.1 - 2.4e-12 46.6 2.5 3.9e-12 45.9 2.5 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MetallophosN PF16371.5 RJW69400.1 - 0.0086 16.3 0.2 0.027 14.7 0.2 1.8 1 0 0 1 1 1 1 N terminal of Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 RJW69403.1 - 1.2e-05 25.7 3.6 0.0016 18.9 0.2 3.0 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW69403.1 - 0.0015 17.9 0.2 0.018 14.5 0.0 2.7 3 0 0 3 3 3 1 EF hand Cep57_MT_bd PF06657.13 RJW69403.1 - 0.0049 17.3 3.5 0.0091 16.4 1.7 2.3 1 1 1 2 2 2 1 Centrosome microtubule-binding domain of Cep57 EF-hand_6 PF13405.6 RJW69403.1 - 0.051 13.5 1.2 1.3 9.2 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain Baculo_PEP_C PF04513.12 RJW69403.1 - 0.41 10.7 3.8 0.8 9.7 1.0 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PriC PF07445.12 RJW69403.1 - 0.61 10.0 5.0 1 9.2 5.0 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC FAM76 PF16046.5 RJW69403.1 - 0.89 8.8 12.4 0.02 14.2 5.3 1.8 2 1 0 2 2 2 0 FAM76 protein Phe_tRNA-synt_N PF02912.18 RJW69403.1 - 1.8 8.6 6.1 2.1 8.3 0.5 3.2 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain SlyX PF04102.12 RJW69403.1 - 2.7 8.7 6.4 1.3e+02 3.3 6.3 3.0 1 1 0 1 1 1 0 SlyX DUF4407 PF14362.6 RJW69403.1 - 3 7.1 7.4 4.5 6.5 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PMC2NT PF08066.12 RJW69403.1 - 4.3 8.1 7.9 0.43 11.3 0.5 3.0 3 1 2 5 5 4 0 PMC2NT (NUC016) domain HisKA PF00512.25 RJW69403.1 - 4.5 7.4 10.6 1.1e+03 -0.3 8.4 3.4 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain TMPIT PF07851.13 RJW69403.1 - 5 6.3 5.2 2.8 7.1 3.0 1.7 1 1 1 2 2 2 0 TMPIT-like protein CorA PF01544.18 RJW69403.1 - 6.7 5.9 9.4 2.4 7.4 6.0 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein bZIP_1 PF00170.21 RJW69404.1 - 1.5e-16 60.2 12.1 3.1e-16 59.2 12.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RJW69404.1 - 4.6e-08 33.0 12.4 1e-07 31.9 12.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RJW69404.1 - 0.021 15.3 7.2 0.051 14.1 7.2 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Pox_F12L PF03337.13 RJW69404.1 - 0.043 12.0 0.3 0.074 11.2 0.3 1.3 1 0 0 1 1 1 0 Poxvirus F12L protein Sif PF06767.11 RJW69404.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Sif protein ASD2 PF08687.11 RJW69404.1 - 0.82 9.2 5.9 0.15 11.6 1.0 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 HALZ PF02183.18 RJW69404.1 - 2.9 8.2 5.0 2.3 8.5 1.4 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper C2 PF00168.30 RJW69406.1 - 2.7e-27 95.0 0.7 3.7e-11 43.2 0.0 4.3 4 0 0 4 4 4 3 C2 domain FerB PF08150.12 RJW69406.1 - 3.3e-24 85.3 0.0 7.3e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 FerB (NUC096) domain FerA PF08165.11 RJW69406.1 - 2.3e-19 69.1 0.9 5.6e-19 67.8 0.4 1.9 2 0 0 2 2 2 1 FerA (NUC095) domain Pex24p PF06398.11 RJW69406.1 - 5.7e-06 25.5 22.0 0.0012 17.9 6.8 3.2 2 1 1 3 3 3 2 Integral peroxisomal membrane peroxin RVT_1 PF00078.27 RJW69407.1 - 1.6e-08 34.3 0.0 3.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LETM1 PF07766.13 RJW69408.1 - 4.4e-96 321.3 5.1 6.9e-96 320.7 5.1 1.3 1 0 0 1 1 1 1 LETM1-like protein Cnd2 PF05786.14 RJW69414.1 - 2e-123 413.7 0.0 3.6e-123 412.9 0.0 1.3 1 0 0 1 1 1 1 Condensin complex subunit 2 HECT PF00632.25 RJW69415.1 - 1e-55 189.4 0.3 8.4e-43 147.0 0.0 2.5 2 1 1 3 3 3 2 HECT-domain (ubiquitin-transferase) GST_N_2 PF13409.6 RJW69415.1 - 0.12 12.7 0.1 57 4.1 0.0 3.2 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain C2 PF00168.30 RJW69417.1 - 2.2e-45 153.2 0.0 2.5e-13 50.2 0.1 4.6 4 0 0 4 4 4 3 C2 domain FerB PF08150.12 RJW69417.1 - 3.4e-30 104.5 0.1 9.4e-30 103.0 0.1 1.8 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.12 RJW69417.1 - 1.3e-17 63.6 0.3 2.6e-17 62.7 0.3 1.6 1 0 0 1 1 1 1 FerI (NUC094) domain FerA PF08165.11 RJW69417.1 - 2.5e-15 56.2 0.2 6.5e-15 54.8 0.2 1.8 1 0 0 1 1 1 1 FerA (NUC095) domain Pex24p PF06398.11 RJW69417.1 - 2.6e-06 26.7 17.7 0.00035 19.7 0.4 3.1 2 1 1 3 3 3 2 Integral peroxisomal membrane peroxin WYL PF13280.6 RJW69417.1 - 0.065 13.3 0.5 0.16 12.0 0.5 1.6 1 0 0 1 1 1 0 WYL domain Acyl-CoA_dh_M PF02770.19 RJW69424.1 - 1e-19 70.5 0.0 1.9e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RJW69424.1 - 2e-05 24.8 0.1 7.6e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TPR_2 PF07719.17 RJW69425.1 - 0.00043 20.2 2.2 4.7 7.6 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW69425.1 - 0.017 15.9 6.1 21 6.3 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 RJW69425.1 - 0.24 12.1 4.7 3.3 8.6 0.1 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RVT_1 PF00078.27 RJW69426.1 - 2.4e-45 154.8 0.0 4e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW69426.1 - 1.1e-05 25.3 0.0 3.2e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW69426.1 - 0.00012 21.7 0.8 0.00027 20.5 0.8 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAP PF00956.18 RJW69428.1 - 8.2e-86 287.5 0.1 1e-85 287.2 0.1 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Strabismus PF06638.11 RJW69429.1 - 9.7e-19 67.4 0.3 1.3e-14 53.7 0.0 2.1 1 1 1 2 2 2 2 Strabismus protein Glyco_hydro_18 PF00704.28 RJW69430.1 - 2.4e-14 53.8 0.0 2.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Complex1_30kDa PF00329.19 RJW69431.1 - 0.16 12.6 0.0 0.2 12.3 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit ANAPC4_WD40 PF12894.7 RJW69432.1 - 9.5e-05 22.6 0.0 1.7 9.0 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW69432.1 - 0.00035 21.3 8.6 0.019 15.8 0.1 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat Sulfotransfer_1 PF00685.27 RJW69433.1 - 6.1e-55 186.6 0.0 8.5e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW69433.1 - 7.4e-12 46.1 0.0 3.6e-09 37.3 0.0 2.3 1 1 0 2 2 2 2 Sulfotransferase family Rad51 PF08423.11 RJW69434.1 - 2.4e-42 145.0 0.0 7.6e-42 143.3 0.0 1.8 1 1 0 1 1 1 1 Rad51 RhoGEF PF00621.20 RJW69434.1 - 2.4e-12 47.5 1.1 4.5e-10 40.1 0.2 3.1 3 0 0 3 3 3 1 RhoGEF domain AAA_25 PF13481.6 RJW69434.1 - 6e-11 42.3 0.0 1.4e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 RJW69434.1 - 2.5e-07 30.3 0.0 1.1e-06 28.2 0.0 2.1 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain ATPase PF06745.13 RJW69434.1 - 2.4e-06 27.1 0.2 1.1e-05 24.9 0.2 2.1 1 1 0 1 1 1 1 KaiC RecA PF00154.21 RJW69434.1 - 2.6e-05 23.8 0.0 0.0017 17.9 0.0 2.3 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_22 PF13401.6 RJW69434.1 - 0.015 15.5 0.1 0.39 11.0 0.1 3.0 2 1 0 2 2 2 0 AAA domain ELO PF01151.18 RJW69435.1 - 2.8e-36 125.3 19.5 3.9e-36 124.9 19.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Rubis-subs-bind PF09273.11 RJW69436.1 - 3.1e-12 47.3 0.0 6.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 RJW69436.1 - 0.00022 21.6 0.0 0.001 19.5 0.0 2.0 1 1 0 1 1 1 1 SET domain PRORP PF16953.5 RJW69438.1 - 1.4e-40 139.3 0.2 2e-40 138.8 0.2 1.3 1 0 0 1 1 1 1 Protein-only RNase P PPR_long PF17177.4 RJW69438.1 - 0.019 14.3 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP SopA PF13981.6 RJW69438.1 - 0.075 13.5 0.0 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 SopA-like central domain DUF678 PF05077.12 RJW69438.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF678) vATP-synt_AC39 PF01992.16 RJW69438.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit Nckap1 PF09735.9 RJW69439.1 - 1.4e-298 993.6 0.7 1.9e-185 619.0 0.0 3.4 3 1 0 3 3 3 3 Membrane-associated apoptosis protein Strabismus PF06638.11 RJW69440.1 - 0.0095 14.6 1.1 0.061 12.0 0.3 2.1 2 0 0 2 2 2 2 Strabismus protein BTB PF00651.31 RJW69441.1 - 1.2e-13 51.3 0.2 5.4e-05 23.4 0.0 3.7 3 1 1 4 4 4 2 BTB/POZ domain BACK PF07707.15 RJW69441.1 - 2.7e-07 30.6 3.0 4.6e-07 29.9 0.6 2.6 2 1 0 2 2 2 1 BTB And C-terminal Kelch Reprolysin PF01421.19 RJW69443.1 - 6.4e-34 117.6 1.1 8.9e-34 117.1 0.2 1.7 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Disintegrin PF00200.23 RJW69443.1 - 6.1e-20 71.8 20.4 6.1e-20 71.8 20.4 3.8 5 0 0 5 5 3 1 Disintegrin ADAM_CR PF08516.12 RJW69443.1 - 4.2e-14 52.9 10.2 2.1e-13 50.7 0.7 3.0 2 0 0 2 2 2 1 ADAM cysteine-rich Reprolysin_5 PF13688.6 RJW69443.1 - 3.7e-13 50.1 0.2 8e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RJW69443.1 - 8.2e-12 45.7 0.1 1.7e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RJW69443.1 - 5.8e-05 22.8 0.7 0.00026 20.7 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RJW69443.1 - 0.00052 20.0 0.2 0.0012 18.8 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 RJW69443.1 - 0.00087 19.6 9.7 0.00087 19.6 9.7 5.5 5 0 0 5 5 3 1 EGF-like domain Peptidase_M57 PF12388.8 RJW69443.1 - 0.11 12.1 0.2 0.31 10.6 0.2 1.7 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.11 RJW69443.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.9 RJW69443.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 adh_short PF00106.25 RJW69444.1 - 3.6e-34 117.9 0.1 4.4e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW69444.1 - 2.5e-31 109.0 0.2 3e-31 108.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Hydrolase_6 PF13344.6 RJW69445.1 - 2.6e-16 59.6 0.0 3.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DNA_methylase PF00145.17 RJW69446.1 - 8.6e-35 120.7 0.0 1.9e-34 119.5 0.0 1.4 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Mog1 PF04603.12 RJW69447.1 - 8.3e-21 74.8 0.1 1.4e-20 74.1 0.1 1.4 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Exo_endo_phos_2 PF14529.6 RJW69447.1 - 0.00074 19.3 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase EAR PF07897.11 RJW69447.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression PTB PF08416.13 RJW69448.1 - 6.1e-20 71.7 0.0 1.6e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 RJW69448.1 - 3.8e-05 23.7 0.0 9.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain PID_2 PF14719.6 RJW69448.1 - 0.00025 21.0 1.8 0.00034 20.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 RJW69448.1 - 0.003 17.6 0.1 0.006 16.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DUF5305 PF17231.2 RJW69450.1 - 0.0012 18.3 3.1 0.0015 17.9 3.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Shisa PF13908.6 RJW69450.1 - 0.013 15.8 0.6 0.018 15.3 0.6 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.6 RJW69450.1 - 0.037 14.3 7.5 0.29 11.5 9.0 1.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4834 PF16118.5 RJW69450.1 - 0.046 14.7 2.3 0.066 14.2 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF929 PF06053.11 RJW69450.1 - 0.081 12.2 7.0 0.13 11.6 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF2207 PF09972.9 RJW69450.1 - 0.1 11.3 0.5 0.13 10.9 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4446 PF14584.6 RJW69450.1 - 0.17 11.8 2.2 0.24 11.4 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TMEM154 PF15102.6 RJW69450.1 - 0.21 11.5 3.9 0.34 10.8 3.9 1.3 1 0 0 1 1 1 0 TMEM154 protein family ODV-E18 PF10717.9 RJW69450.1 - 0.28 11.1 5.3 0.54 10.2 5.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 RJW69450.1 - 0.33 11.9 1.1 0.55 11.1 1.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ASFV_J13L PF05568.11 RJW69450.1 - 0.76 9.5 5.0 1.3 8.8 5.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Baculo_11_kDa PF06143.11 RJW69450.1 - 0.81 9.3 7.0 1.3 8.6 7.0 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Stevor PF17410.2 RJW69450.1 - 1.4 8.4 5.2 2.3 7.7 5.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Synaptobrevin PF00957.21 RJW69450.1 - 2.9 7.8 10.6 5.6 6.8 10.6 1.4 1 0 0 1 1 1 0 Synaptobrevin T2SSF PF00482.23 RJW69450.1 - 9.3 6.2 7.9 18 5.3 7.9 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Tropomyosin PF00261.20 RJW69452.1 - 3.2e-61 206.7 66.3 5.1e-56 189.7 38.0 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 RJW69452.1 - 6.2e-29 101.0 58.7 2.2e-28 99.2 43.6 2.1 1 1 1 2 2 2 2 Tropomyosin like MscS_porin PF12795.7 RJW69452.1 - 3e-06 27.0 44.4 0.00033 20.3 36.8 2.0 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain ERM PF00769.19 RJW69452.1 - 0.0029 17.5 59.6 0.047 13.5 5.8 2.7 1 1 2 3 3 3 1 Ezrin/radixin/moesin family Lebercilin PF15619.6 RJW69452.1 - 0.003 17.3 49.7 0.0059 16.3 23.3 2.6 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Cep57_MT_bd PF06657.13 RJW69452.1 - 0.0033 17.8 4.5 0.0033 17.8 4.5 3.9 1 1 3 4 4 4 1 Centrosome microtubule-binding domain of Cep57 DUF724 PF05266.14 RJW69452.1 - 0.0037 17.1 40.0 0.0051 16.7 22.6 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF724) DUF1664 PF07889.12 RJW69452.1 - 0.0041 17.2 24.3 0.4 10.7 2.6 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) FH2 PF02181.23 RJW69452.1 - 0.0056 15.9 6.1 0.0056 15.9 6.1 3.0 1 1 2 3 3 3 1 Formin Homology 2 Domain HrpB7 PF09486.10 RJW69452.1 - 0.0065 16.9 43.1 0.025 15.0 25.4 2.7 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) AAA_13 PF13166.6 RJW69452.1 - 0.056 12.1 39.2 0.084 11.5 30.4 2.0 1 1 1 2 2 2 0 AAA domain ATG16 PF08614.11 RJW69452.1 - 0.067 13.4 52.0 0.12 12.6 26.8 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BORCS7 PF16088.5 RJW69452.1 - 0.07 13.4 0.3 0.07 13.4 0.3 3.8 1 1 1 3 3 3 0 BLOC-1-related complex sub-unit 7 FPP PF05911.11 RJW69452.1 - 0.071 11.3 46.3 0.011 14.0 29.0 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil HOOK PF05622.12 RJW69452.1 - 0.077 11.1 43.4 0.04 12.1 13.4 2.0 1 1 1 2 2 2 0 HOOK protein Laminin_II PF06009.12 RJW69452.1 - 0.094 12.7 31.2 0.031 14.3 9.5 3.1 1 1 3 4 4 4 0 Laminin Domain II DUF3584 PF12128.8 RJW69452.1 - 0.2 9.2 44.8 0.28 8.7 7.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) SNARE PF05739.19 RJW69452.1 - 0.2 11.7 3.9 0.97 9.5 0.2 3.1 2 1 0 2 2 2 0 SNARE domain Jacalin PF01419.17 RJW69452.1 - 0.26 11.2 1.5 0.36 10.8 0.5 1.7 2 0 0 2 2 2 0 Jacalin-like lectin domain Spc7 PF08317.11 RJW69452.1 - 0.28 10.0 50.6 1.8 7.4 39.4 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Cep57_CLD PF14073.6 RJW69452.1 - 0.29 11.2 46.3 0.24 11.4 19.3 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 FlaC_arch PF05377.11 RJW69452.1 - 0.39 11.2 32.7 0.38 11.2 1.3 4.9 4 2 2 6 6 5 0 Flagella accessory protein C (FlaC) Uds1 PF15456.6 RJW69452.1 - 0.69 10.1 36.7 1.4 9.0 19.1 3.3 1 1 1 2 2 2 0 Up-regulated During Septation ABC_tran_CTD PF16326.5 RJW69452.1 - 0.77 10.1 57.6 0.45 10.8 7.8 4.9 1 1 3 4 4 4 0 ABC transporter C-terminal domain UPF0160 PF03690.13 RJW69452.1 - 0.77 9.3 10.0 0.88 9.1 10.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) DUF4686 PF15742.5 RJW69452.1 - 0.85 8.7 43.3 8.5 5.4 43.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) DUF4200 PF13863.6 RJW69452.1 - 1.1 9.7 53.8 2 8.8 16.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Sec2p PF06428.11 RJW69452.1 - 1.2 9.2 40.3 1.7 8.7 10.2 3.8 1 1 3 4 4 4 0 GDP/GTP exchange factor Sec2p TPR_MLP1_2 PF07926.12 RJW69452.1 - 1.2 9.2 52.9 3.2 7.8 10.8 3.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 RJW69452.1 - 1.3 9.2 26.7 2.7 8.2 3.4 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4600 PF15372.6 RJW69452.1 - 1.7 9.1 34.1 0.12 12.8 3.0 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) DUF4201 PF13870.6 RJW69452.1 - 1.7 8.3 37.6 0.48 10.1 21.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Lectin_N PF03954.14 RJW69452.1 - 1.8 8.3 20.8 4 7.2 3.2 3.3 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain T3SSipB PF16535.5 RJW69452.1 - 1.9 9.0 34.7 0.21 12.1 3.1 3.1 1 1 2 3 3 3 0 Type III cell invasion protein SipB Exonuc_VII_L PF02601.15 RJW69452.1 - 2.1 7.9 30.9 2.2e+02 1.2 30.9 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit HemX PF04375.14 RJW69452.1 - 2.5 7.3 35.4 1.7 7.9 3.3 2.7 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spectrin PF00435.21 RJW69452.1 - 3 8.4 39.5 8.8 6.9 1.3 3.2 1 1 2 3 3 3 0 Spectrin repeat BRE1 PF08647.11 RJW69452.1 - 3.3 7.8 47.2 0.31 11.1 15.1 3.2 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4472 PF14739.6 RJW69452.1 - 4.4 8.1 38.8 3.4 8.5 19.2 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) Seryl_tRNA_N PF02403.22 RJW69452.1 - 5 7.4 43.7 0.14 12.4 19.4 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Pox_A_type_inc PF04508.12 RJW69452.1 - 5.7 7.0 16.2 1.8 8.5 0.4 5.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Golgin_A5 PF09787.9 RJW69452.1 - 6.3 6.2 45.3 3.5 7.0 28.4 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Alanine_zipper PF11839.8 RJW69452.1 - 7 7.1 34.3 0.72 10.3 2.5 4.2 3 2 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein NBP1 PF08537.10 RJW69452.1 - 7.8 5.8 30.5 3 7.2 18.6 2.5 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 DUF2203 PF09969.9 RJW69452.1 - 8.9 7.1 31.9 3.9 8.2 3.8 3.2 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2203) Fez1 PF06818.15 RJW69452.1 - 9.5 6.6 45.3 7.3 7.0 7.3 2.3 1 1 1 2 2 2 0 Fez1 Tetraspanin PF00335.20 RJW69454.1 - 4.1e-25 88.9 11.5 4.9e-25 88.6 11.5 1.1 1 0 0 1 1 1 1 Tetraspanin family Amastin PF07344.11 RJW69454.1 - 0.21 11.4 9.7 2.1 8.2 4.2 2.4 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF3185 PF11381.8 RJW69454.1 - 0.3 11.1 8.1 2.1 8.4 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Phage_holin_3_6 PF07332.11 RJW69454.1 - 2.3 8.3 12.9 0.63 10.1 4.9 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III EI24 PF07264.11 RJW69454.1 - 5 7.3 11.8 30 4.8 11.8 1.9 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) MatB PF16449.5 RJW69455.1 - 0.031 14.1 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Fimbrillin MatB MFS_1 PF07690.16 RJW69457.1 - 1.1e-12 47.6 38.8 6e-08 32.0 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_3 PF12698.7 RJW69457.1 - 0.076 12.1 5.8 0.13 11.4 5.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-C2H2_4 PF13894.6 RJW69459.1 - 1.4e-09 38.0 14.5 7.6e-05 23.2 0.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW69459.1 - 2.4e-07 30.8 14.8 1.9e-06 28.0 0.7 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW69459.1 - 0.00016 21.9 17.2 0.076 13.5 0.1 4.4 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 RJW69459.1 - 0.0041 17.8 3.4 0.056 14.1 0.8 2.3 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 RJW69459.1 - 0.0077 16.0 19.1 0.52 10.1 1.2 3.6 4 0 0 4 4 3 3 zinc-finger C2H2-type zf_UBZ PF18439.1 RJW69459.1 - 0.0093 15.5 0.9 1.4 8.6 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Rpr2 PF04032.16 RJW69459.1 - 0.0099 16.1 1.0 0.25 11.7 1.2 2.3 1 1 1 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_5 PF13909.6 RJW69459.1 - 0.018 14.8 0.6 0.018 14.8 0.6 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 RJW69459.1 - 0.024 15.1 0.8 0.024 15.1 0.8 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 RJW69459.1 - 0.042 14.2 4.2 0.98 9.8 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HypA PF01155.19 RJW69459.1 - 0.053 13.6 0.1 0.083 12.9 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 RJW69459.1 - 0.064 13.3 1.4 0.064 13.3 1.4 2.6 1 1 1 2 2 2 0 BED zinc finger YhfH PF14149.6 RJW69459.1 - 0.066 13.2 2.2 13 5.9 0.1 3.0 3 0 0 3 3 3 0 YhfH-like protein ADK_lid PF05191.14 RJW69459.1 - 0.071 13.1 0.9 5.6 7.0 1.0 2.8 1 1 1 2 2 2 0 Adenylate kinase, active site lid DZR PF12773.7 RJW69459.1 - 0.11 12.5 0.9 0.32 11.0 0.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_12 PF18658.1 RJW69459.1 - 0.13 11.9 1.0 1.8 8.2 0.0 2.6 1 1 1 2 2 2 0 Zinc-finger C2H2-type CpXC PF14353.6 RJW69459.1 - 0.15 12.1 0.9 17 5.5 0.1 2.2 1 1 1 2 2 2 0 CpXC protein TF_Zn_Ribbon PF08271.12 RJW69459.1 - 0.27 10.8 1.5 1.1 8.8 1.5 1.9 1 1 1 2 2 2 0 TFIIB zinc-binding zf-C2H2_2 PF12756.7 RJW69459.1 - 0.79 10.1 5.8 6.6 7.1 0.7 2.5 2 1 1 3 3 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 RJW69459.1 - 0.86 9.7 15.0 0.49 10.5 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-3CxxC PF13695.6 RJW69459.1 - 2.3 8.7 5.9 2.9 8.4 0.3 2.6 1 1 2 3 3 3 0 Zinc-binding domain XPA_N PF01286.18 RJW69459.1 - 5.6 7.1 6.2 0.73 9.9 0.3 2.4 3 0 0 3 3 3 0 XPA protein N-terminal Tetraspanin PF00335.20 RJW69462.1 - 1.5e-38 132.8 6.6 1.7e-38 132.6 6.6 1.0 1 0 0 1 1 1 1 Tetraspanin family MFP2b PF12150.8 RJW69462.1 - 0.069 12.4 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytosolic motility protein Med26_M PF15694.5 RJW69463.1 - 0.003 17.7 0.1 0.005 16.9 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit 26 middle domain Leu_zip PF15294.6 RJW69469.1 - 0.0077 15.8 13.9 0.0077 15.8 13.9 3.2 2 1 1 3 3 3 1 Leucine zipper Uso1_p115_C PF04871.13 RJW69469.1 - 0.015 15.6 6.2 0.015 15.6 6.2 4.6 4 1 0 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3313 PF11769.8 RJW69469.1 - 0.017 15.0 1.3 0.043 13.6 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) DUF1664 PF07889.12 RJW69469.1 - 6.4 6.8 26.1 0.89 9.6 1.0 4.9 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) RVT_1 PF00078.27 RJW69470.1 - 3.1e-18 66.1 0.3 7.7e-12 45.2 0.0 3.0 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW69470.1 - 0.0008 19.0 0.5 0.0022 17.6 0.5 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1676 PF07898.13 RJW69471.1 - 1.9 8.5 17.5 2.5 8.1 17.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) PH_8 PF15409.6 RJW69473.1 - 0.039 14.2 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Tetraspanin PF00335.20 RJW69474.1 - 4e-11 43.1 8.1 4.6e-11 42.9 8.1 1.1 1 0 0 1 1 1 1 Tetraspanin family AMOP PF03782.17 RJW69474.1 - 0.043 13.9 2.4 0.5 10.5 0.1 2.4 3 0 0 3 3 3 0 AMOP domain zf-H2C2_2 PF13465.6 RJW69475.1 - 5.9e-27 92.9 26.1 1.2e-08 35.0 0.2 5.0 5 0 0 5 5 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 RJW69475.1 - 5.4e-21 73.8 34.2 1e-06 28.9 1.0 5.3 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW69475.1 - 4.2e-15 55.1 28.9 0.00099 19.8 2.5 5.4 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW69475.1 - 2.4e-12 46.8 6.0 0.0025 18.1 0.4 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW69475.1 - 2.7e-06 27.2 24.0 0.0054 16.7 1.3 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 RJW69475.1 - 8.1e-06 25.6 15.4 0.29 11.1 0.1 4.8 4 0 0 4 4 4 4 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 RJW69475.1 - 3.2e-05 23.6 21.2 0.024 14.4 4.0 4.2 4 0 0 4 4 4 3 zinc-finger C2H2-type zf_UBZ PF18439.1 RJW69475.1 - 4.7e-05 22.9 7.5 0.083 12.5 0.1 4.5 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 RJW69475.1 - 0.0004 21.1 4.9 0.14 12.9 0.3 2.9 1 1 1 2 2 2 2 zinc-ribbon family DZR PF12773.7 RJW69475.1 - 0.0039 17.2 8.5 0.46 10.5 8.5 3.4 1 1 0 1 1 1 1 Double zinc ribbon XPA_N PF01286.18 RJW69475.1 - 0.008 16.2 10.1 5.2 7.2 0.2 4.4 4 0 0 4 4 4 1 XPA protein N-terminal zf-met PF12874.7 RJW69475.1 - 0.013 15.9 17.3 0.52 10.8 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 RJW69475.1 - 0.027 14.6 13.4 0.61 10.2 2.5 4.5 2 1 3 5 5 5 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 RJW69475.1 - 0.069 13.1 6.7 1.2 9.1 0.7 4.2 3 1 0 3 3 3 0 zinc-ribbon domain DUF2256 PF10013.9 RJW69475.1 - 0.25 11.5 4.5 31 4.8 0.0 4.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 RJW69475.1 - 0.28 10.8 3.4 30 4.3 0.1 3.8 2 2 2 4 4 4 0 MYST family zinc finger domain zf-trcl PF13451.6 RJW69475.1 - 0.42 10.5 8.4 4.4 7.3 0.1 3.7 4 0 0 4 4 3 0 Probable zinc-ribbon domain DUF3268 PF11672.8 RJW69475.1 - 0.88 9.9 5.1 0.9 9.9 0.5 2.4 1 1 2 3 3 3 0 zinc-finger-containing domain ADK_lid PF05191.14 RJW69475.1 - 0.99 9.4 13.2 0.15 12.1 0.9 3.5 2 1 1 3 3 3 0 Adenylate kinase, active site lid CpXC PF14353.6 RJW69475.1 - 1.2 9.2 6.3 7.1 6.7 0.0 3.7 1 1 3 4 4 4 0 CpXC protein LIM PF00412.22 RJW69475.1 - 1.6 9.0 11.2 11 6.4 2.4 3.5 2 1 0 2 2 2 0 LIM domain zf-AN1 PF01428.16 RJW69475.1 - 2 8.6 17.3 9.8 6.4 0.1 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger zf-RING_7 PF02591.15 RJW69475.1 - 3.2 8.0 10.3 13 6.1 0.0 4.7 5 0 0 5 5 4 0 C4-type zinc ribbon domain Syntaxin PF00804.25 RJW69479.1 - 0.005 16.5 0.4 5.2 6.7 0.0 3.1 3 0 0 3 3 3 2 Syntaxin Tup_N PF08581.10 RJW69479.1 - 0.0076 16.5 3.9 0.07 13.4 0.1 2.7 2 0 0 2 2 2 1 Tup N-terminal EzrA PF06160.12 RJW69479.1 - 0.014 13.6 1.4 0.065 11.4 0.2 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Laminin_II PF06009.12 RJW69479.1 - 0.021 14.9 3.5 0.5 10.4 0.2 2.3 2 0 0 2 2 2 0 Laminin Domain II HIP1_clath_bdg PF16515.5 RJW69479.1 - 0.093 13.4 2.7 3.6 8.2 0.3 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MAAL_N PF05034.13 RJW69479.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus V_ATPase_I PF01496.19 RJW69479.1 - 0.19 9.6 0.0 1.8 6.3 0.0 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 RJW69479.1 - 4 8.0 7.6 3.4 8.2 0.6 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region FBPase PF00316.20 RJW69480.1 - 3.1e-56 189.8 0.8 4.1e-56 189.5 0.8 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 RJW69480.1 - 0.03 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family Oxygenase-NA PF09859.9 RJW69480.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Tetraspanin PF00335.20 RJW69482.1 - 2.3e-20 73.3 13.6 2.7e-20 73.1 13.6 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF5083 PF16890.5 RJW69482.1 - 0.031 14.0 1.2 0.062 13.0 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) PI3_PI4_kinase PF00454.27 RJW69483.1 - 6.7e-35 121.1 0.0 7.6e-23 81.6 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RJW69483.1 - 7.6e-05 22.2 0.2 0.00014 21.3 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) WI12 PF07107.11 RJW69483.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Wound-induced protein WI12 wnt PF00110.19 RJW69484.1 - 2.6e-93 313.0 17.0 3.5e-93 312.6 17.0 1.1 1 0 0 1 1 1 1 wnt family MamL-1 PF09596.10 RJW69484.1 - 0.017 15.3 0.0 0.064 13.5 0.0 2.0 1 0 0 1 1 1 0 MamL-1 domain Peptidase_M57 PF12388.8 RJW69484.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Zw10 PF06248.13 RJW69486.1 - 1.5e-08 33.7 12.5 4.7e-08 32.1 5.1 3.8 3 1 0 3 3 3 2 Centromere/kinetochore Zw10 Bap31 PF05529.12 RJW69489.1 - 3.5e-35 120.8 7.7 3.5e-35 120.8 7.7 1.5 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 RJW69489.1 - 6.6e-13 48.5 9.0 6.6e-13 48.5 9.0 2.3 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF812 PF05667.11 RJW69489.1 - 0.00029 19.9 7.7 0.00034 19.7 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF1664 PF07889.12 RJW69489.1 - 0.0059 16.6 5.4 0.0093 16.0 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CC2-LZ PF16516.5 RJW69489.1 - 0.071 13.5 9.5 2.9 8.3 8.4 2.6 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DivIC PF04977.15 RJW69489.1 - 0.086 12.6 13.2 0.82 9.5 0.7 3.9 2 1 2 4 4 4 0 Septum formation initiator Cluap1 PF10234.9 RJW69489.1 - 0.12 11.7 12.6 0.2 11.0 12.6 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Spc7 PF08317.11 RJW69489.1 - 0.14 11.1 14.3 0.22 10.3 14.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 RJW69489.1 - 0.21 11.7 13.6 0.44 10.6 13.6 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 RJW69489.1 - 0.32 10.3 15.9 0.11 11.9 13.0 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 RJW69489.1 - 0.34 10.4 6.9 0.39 10.2 6.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 RJW69489.1 - 1.7 7.1 6.6 2.2 6.8 6.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CREPT PF16566.5 RJW69489.1 - 1.7 8.8 11.3 0.51 10.5 8.4 1.6 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4736 PF15883.5 RJW69489.1 - 1.9 8.1 10.6 2.9 7.6 1.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4736) YabA PF06156.13 RJW69489.1 - 2.1 9.0 10.0 0.64 10.7 5.0 2.5 1 1 2 3 3 3 0 Initiation control protein YabA TDA11 PF17084.5 RJW69489.1 - 2.4 7.0 13.1 0.53 9.2 0.7 2.0 1 1 1 2 2 2 0 Topoisomerase I damage affected protein 11 APG6_N PF17675.1 RJW69489.1 - 3.5 8.2 19.3 10 6.6 19.3 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 RJW69489.1 - 3.9 7.7 20.2 0.2 11.9 13.4 2.1 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4404 PF14357.6 RJW69489.1 - 7.4 7.3 16.4 0.13 12.9 8.0 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4404) SlyX PF04102.12 RJW69489.1 - 7.6 7.2 15.1 1.8 9.2 1.1 3.2 2 1 2 4 4 4 0 SlyX UPF0242 PF06785.11 RJW69489.1 - 8.3 6.5 22.8 50 3.9 22.8 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DHHC PF01529.20 RJW69489.1 - 8.7 6.5 6.9 3.1 7.9 3.8 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase RVT_1 PF00078.27 RJW69491.1 - 4.6e-06 26.3 0.0 7.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Adap_comp_sub PF00928.21 RJW69492.1 - 5.2e-21 75.2 0.0 7.7e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RJW69492.1 - 5.1e-05 23.2 0.3 7.9e-05 22.6 0.3 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HECT PF00632.25 RJW69493.1 - 4.4e-85 285.9 0.0 6e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 RJW69493.1 - 4.9e-47 157.7 20.8 8.8e-13 48.1 0.7 4.6 4 0 0 4 4 4 4 WW domain C2 PF00168.30 RJW69493.1 - 1.3e-13 51.1 0.1 3e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 C2 domain MbtH PF03621.13 RJW69493.1 - 3.7 7.1 9.9 31 4.1 0.6 4.7 5 1 1 6 6 6 0 MbtH-like protein Tetraspanin PF00335.20 RJW69495.1 - 2e-22 80.1 10.2 2.3e-22 79.8 10.2 1.0 1 0 0 1 1 1 1 Tetraspanin family RVT_1 PF00078.27 RJW69497.1 - 9.3e-05 22.0 0.0 0.00051 19.6 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Guanylate_cyc PF00211.20 RJW69498.1 - 2.1e-59 200.3 0.0 3.5e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 RJW69498.1 - 2.8e-28 99.0 0.0 4.7e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 RJW69498.1 - 2.1e-26 92.8 0.0 1.6e-19 70.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW69498.1 - 6e-26 91.4 0.0 3.8e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain HNOBA PF07701.14 RJW69498.1 - 2e-05 24.2 0.8 3.6e-05 23.3 0.8 1.4 1 0 0 1 1 1 1 Heme NO binding associated TPD52 PF04201.15 RJW69499.1 - 7.2e-25 87.5 3.7 1.2e-24 86.7 3.7 1.3 1 0 0 1 1 1 1 Tumour protein D52 family IL12 PF03039.14 RJW69499.1 - 0.055 12.8 0.5 0.086 12.2 0.5 1.2 1 0 0 1 1 1 0 Interleukin-12 alpha subunit ThiS PF02597.20 RJW69499.1 - 0.076 13.7 0.1 7.6 7.2 0.0 2.5 2 0 0 2 2 2 0 ThiS family TORC_N PF12884.7 RJW69500.1 - 0.00018 22.2 0.0 0.00033 21.4 0.0 1.4 1 0 0 1 1 1 1 Transducer of regulated CREB activity, N terminus DUF4042 PF13251.6 RJW69502.1 - 3.4e-21 75.8 0.8 1.5e-18 67.1 0.5 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 RJW69502.1 - 0.69 10.5 3.1 30 5.3 0.8 3.6 3 0 0 3 3 3 0 HEAT-like repeat DUF1604 PF07713.13 RJW69503.1 - 0.055 13.3 0.1 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) YqgC PF17430.2 RJW69503.1 - 0.11 12.6 0.4 9.6 6.4 0.2 2.8 2 1 0 2 2 2 0 Uncharacterized YqgC-like PP2C_C PF07830.13 RJW69503.1 - 0.15 12.5 0.0 25 5.4 0.0 2.5 2 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain AAA_8 PF12780.7 RJW69504.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 DUF4188 PF13826.6 RJW69506.1 - 0.045 14.1 0.2 0.085 13.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) Gemini_mov PF01708.16 RJW69507.1 - 0.49 10.2 1.5 0.95 9.3 1.5 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein PD40 PF07676.12 RJW69511.1 - 0.061 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Piwi PF02171.17 RJW69513.1 - 2.1e-115 385.2 0.0 3e-115 384.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 RJW69513.1 - 1.2e-31 108.8 0.0 3.6e-31 107.2 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 RJW69513.1 - 2.4e-27 95.4 0.5 4.1e-27 94.6 0.5 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 RJW69513.1 - 2.4e-26 93.0 0.1 8e-26 91.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 RJW69513.1 - 5.9e-23 80.3 0.1 1.3e-22 79.2 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 RJW69513.1 - 7.2e-14 51.9 0.7 1.5e-13 50.9 0.1 1.9 2 0 0 2 2 2 1 Argonaute linker 2 domain Cytadhesin_P30 PF07271.11 RJW69514.1 - 0.021 14.4 0.0 0.046 13.3 0.0 1.4 1 1 0 1 1 1 0 Cytadhesin P30/P32 AAA PF00004.29 RJW69515.1 - 1.2e-53 181.1 0.1 2e-41 141.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW69515.1 - 1e-11 44.4 0.0 2.6e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RJW69515.1 - 9.3e-07 29.4 0.0 0.019 15.3 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 RJW69515.1 - 1.1e-06 28.9 0.2 0.0033 17.7 0.0 3.8 2 2 1 3 3 3 1 AAA domain TIP49 PF06068.13 RJW69515.1 - 1.3e-06 27.9 0.0 0.007 15.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 RJW69515.1 - 2e-06 28.3 0.0 0.069 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 RJW69515.1 - 5.1e-06 26.2 0.2 2.3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 RuvB_N PF05496.12 RJW69515.1 - 5.9e-06 26.1 0.4 0.015 15.0 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RJW69515.1 - 1.1e-05 25.6 0.0 7.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RJW69515.1 - 1.2e-05 25.3 0.7 0.0016 18.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RJW69515.1 - 2.6e-05 24.4 0.0 0.25 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 RJW69515.1 - 6.1e-05 22.8 0.1 0.074 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 RJW69515.1 - 8.3e-05 22.6 0.0 0.07 13.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 RJW69515.1 - 9.7e-05 21.8 0.7 0.0064 15.9 0.2 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 RJW69515.1 - 0.00072 19.9 0.0 0.063 13.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 RJW69515.1 - 0.0011 19.0 0.0 0.58 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 RJW69515.1 - 0.0013 18.2 0.3 0.006 16.0 0.1 2.2 3 0 0 3 3 3 1 KaiC AAA_3 PF07726.11 RJW69515.1 - 0.0018 18.2 0.1 0.074 12.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 RJW69515.1 - 0.0027 17.5 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 RJW69515.1 - 0.0051 16.7 0.1 19 5.1 0.0 3.9 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 RJW69515.1 - 0.0059 16.2 0.2 2.9 7.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RJW69515.1 - 0.0069 16.1 0.1 0.4 10.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein IPT PF01745.16 RJW69515.1 - 0.0082 15.6 0.2 0.47 9.8 0.0 2.7 3 0 0 3 3 3 1 Isopentenyl transferase NACHT PF05729.12 RJW69515.1 - 0.0095 15.9 0.2 2.8 7.8 0.0 3.5 4 0 0 4 4 4 1 NACHT domain AAA_19 PF13245.6 RJW69515.1 - 0.012 16.0 0.8 0.94 9.8 0.1 3.6 5 0 0 5 5 3 0 AAA domain Parvo_NS1 PF01057.17 RJW69515.1 - 0.012 14.7 0.0 0.59 9.2 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 CDC48_N PF02359.18 RJW69515.1 - 0.013 15.7 0.0 0.053 13.7 0.0 2.0 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain AAA_7 PF12775.7 RJW69515.1 - 0.02 14.4 0.0 0.057 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 RJW69515.1 - 0.058 13.9 0.0 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 RJW69515.1 - 0.063 13.0 1.3 0.28 10.9 0.0 2.6 4 0 0 4 4 3 0 AAA domain Sigma54_activat PF00158.26 RJW69515.1 - 0.072 12.8 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Hydin_ADK PF17213.3 RJW69515.1 - 0.081 13.2 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Rad17 PF03215.15 RJW69515.1 - 0.083 12.8 0.0 7.8 6.4 0.0 2.9 2 1 1 3 3 3 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 RJW69515.1 - 0.093 12.5 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 RJW69515.1 - 0.12 12.7 0.0 17 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Peptidase_S9 PF00326.21 RJW69518.1 - 4.8e-45 153.6 0.0 8e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 RJW69518.1 - 2.4e-38 131.8 0.0 3.8e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.18 RJW69518.1 - 8.8e-06 25.5 0.1 0.00011 21.9 0.1 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 RJW69518.1 - 4.7e-05 23.2 0.0 8.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 RJW69518.1 - 0.00011 21.6 0.8 0.0028 17.0 0.2 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S28 PF05577.12 RJW69518.1 - 0.0011 17.8 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.7 RJW69518.1 - 0.0011 19.6 2.4 0.0017 19.0 0.1 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RJW69518.1 - 0.0018 18.1 0.0 0.0077 16.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 RJW69518.1 - 0.0045 16.8 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 RJW69518.1 - 0.025 14.1 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase AXE1 PF05448.12 RJW69518.1 - 0.039 12.6 0.1 0.47 9.1 0.1 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF3141 PF11339.8 RJW69518.1 - 0.069 11.6 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DLH PF01738.18 RJW69518.1 - 0.13 11.8 0.0 1.1 8.8 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family PNRC PF15365.6 RJW69519.1 - 0.23 11.3 0.8 0.61 10.0 0.8 1.8 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif A_amylase_inhib PF01356.19 RJW69520.1 - 0.09 12.8 5.3 0.29 11.2 0.2 2.8 2 1 1 3 3 3 0 Alpha amylase inhibitor Coatomer_WDAD PF04053.14 RJW69521.1 - 7.5e-147 490.0 0.0 3e-146 488.0 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 RJW69521.1 - 5.9e-40 134.5 4.4 1.4e-07 32.1 0.0 7.9 9 0 0 9 9 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW69521.1 - 5.2e-06 26.7 1.6 2.7 8.3 0.1 5.2 2 2 4 6 6 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW69521.1 - 0.00023 20.0 4.7 1.5 7.4 0.0 4.6 2 2 4 6 6 6 2 Nucleoporin Nup120/160 BUD22 PF09073.10 RJW69521.1 - 0.011 15.1 14.8 0.016 14.6 14.8 1.2 1 0 0 1 1 1 0 BUD22 BBS2_Mid PF14783.6 RJW69521.1 - 0.012 15.7 0.1 5.8 7.0 0.0 3.9 3 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PPP4R2 PF09184.11 RJW69521.1 - 0.03 13.9 16.1 0.048 13.3 16.1 1.3 1 0 0 1 1 1 0 PPP4R2 Nucleoporin_N PF08801.11 RJW69521.1 - 0.048 12.4 0.1 9.2 4.9 0.0 3.4 2 1 0 2 2 2 0 Nup133 N terminal like Cwf_Cwc_15 PF04889.12 RJW69521.1 - 0.087 12.5 16.9 0.15 11.7 16.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 RJW69521.1 - 0.1 10.7 32.1 0.18 9.9 32.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi CSRNP_N PF16019.5 RJW69521.1 - 0.12 12.2 2.7 0.22 11.4 2.7 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Na_trans_assoc PF06512.13 RJW69521.1 - 0.31 11.3 15.1 0.51 10.6 15.1 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Merozoite_SPAM PF07133.11 RJW69521.1 - 1.2 9.1 38.4 1.9 8.5 38.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 RJW69521.1 - 1.4 8.3 26.3 2.2 7.6 26.3 1.2 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 RJW69521.1 - 1.6 8.0 29.3 33 3.7 0.0 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 RJW69521.1 - 2.8 6.1 29.0 4.5 5.4 29.0 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 RJW69521.1 - 2.8 7.7 18.7 5.7 6.7 18.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4820 PF16091.5 RJW69521.1 - 4.6 6.5 7.2 7.6 5.8 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CDC45 PF02724.14 RJW69523.1 - 2.8 6.1 7.8 4 5.6 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 RJW69523.1 - 9.9 4.8 5.2 18 4.0 5.2 1.4 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 RJW69524.1 - 2.8e-09 36.8 0.0 4.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RHD_DNA_bind PF00554.22 RJW69526.1 - 1e-21 77.6 0.0 5.8e-21 75.2 0.0 2.1 1 1 0 1 1 1 1 Rel homology DNA-binding domain Menin PF05053.13 RJW69526.1 - 0.026 12.9 1.5 0.045 12.1 1.5 1.2 1 0 0 1 1 1 0 Menin RHD_dimer PF16179.5 RJW69526.1 - 0.028 14.4 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Rel homology dimerisation domain PDE4_UCR PF18100.1 RJW69527.1 - 1.2e-08 35.6 0.3 3.7e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) WD40 PF00400.32 RJW69528.1 - 2.4e-33 113.6 26.4 3.4e-05 24.5 0.1 11.5 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW69528.1 - 5.7e-08 33.0 0.3 5.2 7.4 0.0 6.9 3 3 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RJW69528.1 - 0.0052 16.2 6.9 0.018 14.4 0.1 4.0 3 2 2 5 5 5 2 WD40-like domain CPSF_A PF03178.15 RJW69528.1 - 0.084 12.2 0.4 1.3 8.2 0.0 3.1 4 1 1 5 5 5 0 CPSF A subunit region zf-C2H2_4 PF13894.6 RJW69529.1 - 0.23 12.4 8.5 3.5 8.7 1.5 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger Ldh_1_N PF00056.23 RJW69530.1 - 5.5e-42 143.2 0.8 5.5e-42 143.2 0.8 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 RJW69530.1 - 6.5e-22 78.2 0.0 1.1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 RJW69530.1 - 0.024 14.2 0.1 0.053 13.1 0.1 1.6 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Poly_export PF02563.16 RJW69530.1 - 0.031 14.5 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein AlaDh_PNT_C PF01262.21 RJW69530.1 - 0.081 12.2 1.2 0.15 11.4 1.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Mito_carr PF00153.27 RJW69531.1 - 4e-60 199.8 1.7 6.1e-22 77.3 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein RVT_1 PF00078.27 RJW69532.1 - 0.026 14.1 0.0 0.096 12.2 0.0 1.8 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3789 PF12664.7 RJW69533.1 - 0.19 11.4 1.2 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) PAP2 PF01569.21 RJW69534.1 - 7.3e-26 90.6 2.6 7.3e-26 90.6 2.6 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 RJW69534.1 - 0.023 14.4 12.9 0.081 12.6 12.9 1.8 1 1 0 1 1 1 0 PAP2 superfamily UPF0242 PF06785.11 RJW69534.1 - 0.065 13.3 2.4 0.12 12.5 2.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF373 PF04123.13 RJW69534.1 - 1.5 8.2 6.7 0.32 10.4 2.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF373) PAP2_C PF14360.6 RJW69534.1 - 4.7 7.8 17.9 0.052 14.1 2.2 3.2 3 1 0 3 3 3 0 PAP2 superfamily C-terminal RseC_MucC PF04246.12 RJW69534.1 - 8.5 6.3 7.7 8.3 6.4 3.7 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SNF2_N PF00176.23 RJW69535.1 - 1.7e-51 175.0 0.3 2.5e-51 174.4 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW69535.1 - 3.6e-20 72.4 0.0 2.9e-18 66.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW69535.1 - 4.8e-08 33.2 0.0 1.5e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_3 PF12836.7 RJW69535.1 - 0.044 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif PDEase_I PF00233.19 RJW69536.1 - 5.9e-86 288.1 0.8 9.4e-86 287.4 0.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 RJW69536.1 - 9.9e-32 110.1 0.0 2.4e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Phosphodiesterase 4 upstream conserved regions (UCR) Sulfate_transp PF00916.20 RJW69537.1 - 3.3e-86 289.4 17.0 5.4e-86 288.7 17.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 RJW69537.1 - 9.8e-06 25.2 0.1 2.3e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 STAS domain Gcd10p PF04189.13 RJW69537.1 - 0.047 12.8 0.1 0.085 12.0 0.0 1.4 2 0 0 2 2 2 0 Gcd10p family DUF3340 PF11818.8 RJW69537.1 - 0.44 10.7 5.6 0.65 10.2 5.6 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) PGI PF00342.19 RJW69539.1 - 4e-247 820.6 0.4 4.9e-247 820.3 0.4 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase GMC_oxred_C PF05199.13 RJW69542.1 - 3.9e-25 89.0 0.0 6.6e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 RJW69542.1 - 1.7e-08 34.2 0.0 2.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DprA_WH PF17782.1 RJW69543.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 DprA winged helix domain Ras PF00071.22 RJW69544.1 - 2.2e-08 33.9 0.0 4.3e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.6 RJW69544.1 - 0.0027 18.0 0.0 0.0055 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 RJW69544.1 - 0.0065 16.5 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 RJW69544.1 - 0.02 15.3 0.0 0.046 14.1 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 RJW69544.1 - 0.023 15.2 0.0 0.033 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RJW69544.1 - 0.032 14.8 0.0 0.053 14.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 RJW69544.1 - 0.064 13.5 0.0 0.49 10.6 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 RJW69544.1 - 0.098 13.1 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW69544.1 - 0.1 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 RJW69544.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.27 RJW69544.1 - 0.15 11.6 0.1 0.35 10.4 0.1 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 RJW69544.1 - 0.17 11.6 0.1 0.36 10.6 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Apt1 PF10351.9 RJW69547.1 - 0.093 11.6 4.3 0.1 11.5 4.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop14 PF04147.12 RJW69547.1 - 0.63 8.2 21.3 0.64 8.2 21.3 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RJW69547.1 - 0.67 8.2 20.8 0.74 8.0 20.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 RJW69547.1 - 1 9.4 13.3 1.2 9.2 13.3 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 RJW69547.1 - 2.7 7.7 12.6 3.1 7.5 12.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 RJW69547.1 - 3.1 6.7 4.8 2.9 6.8 4.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GMC_oxred_N PF00732.19 RJW69548.1 - 0.0033 16.9 0.0 0.05 13.0 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase hSac2 PF12456.8 RJW69550.1 - 3.4e-16 59.0 0.1 6.1e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 Inositol phosphatase Sema PF01403.19 RJW69552.1 - 1.4e-20 73.5 0.0 2.1e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.19 RJW69552.1 - 1.8e-17 63.3 17.1 8.4e-09 35.5 2.8 3.2 2 0 0 2 2 2 2 Thrombospondin type 1 domain EMP24_GP25L PF01105.24 RJW69553.1 - 3.7e-18 66.1 2.7 4e-18 66.0 2.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_A17 PF05380.13 RJW69554.1 - 1.4e-24 86.9 0.1 2.2e-24 86.3 0.1 1.2 1 0 0 1 1 1 1 Pao retrotransposon peptidase SAPS PF04499.15 RJW69555.1 - 0.63 8.8 4.9 0.61 8.8 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 RJW69555.1 - 0.78 7.9 34.6 0.95 7.6 34.6 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RJW69555.1 - 2.8 5.9 49.3 3.9 5.5 49.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RJW69555.1 - 4.6 5.4 27.6 6.4 4.9 27.6 1.2 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 RJW69555.1 - 5.8 5.6 6.5 8.6 5.0 6.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRM_1 PF00076.22 RJW69561.1 - 1.7e-14 53.4 0.0 2.9e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW69561.1 - 0.00028 20.5 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW69561.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif EMP24_GP25L PF01105.24 RJW69562.1 - 7.5e-09 35.8 0.0 9.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Bowman-Birk_leg PF00228.20 RJW69562.1 - 0.057 13.8 5.3 0.12 12.8 5.3 1.6 1 0 0 1 1 1 0 Bowman-Birk serine protease inhibitor family Methyltransf_PK PF05891.12 RJW69563.1 - 1.7e-71 240.2 0.0 3.1e-71 239.4 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 RJW69563.1 - 6.5e-05 23.6 0.0 0.00016 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RJW69563.1 - 0.00014 22.5 0.0 0.00031 21.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 RJW69563.1 - 0.0022 17.3 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 RJW69563.1 - 0.0057 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Nucleoporin_FG PF13634.6 RJW69563.1 - 0.49 11.3 172.6 0.041 14.7 20.7 10.1 2 1 7 9 9 9 0 Nucleoporin FG repeat region PI3_PI4_kinase PF00454.27 RJW69564.1 - 2.7e-49 168.2 0.0 2.9e-48 164.9 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RJW69564.1 - 1.2e-33 116.1 0.1 4.6e-21 75.1 0.0 2.5 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_p85B PF02192.16 RJW69564.1 - 6e-20 70.8 0.2 1.8e-19 69.3 0.2 1.9 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_C2 PF00792.24 RJW69564.1 - 6.5e-17 61.8 0.0 1.4e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 RJW69564.1 - 2.1e-05 24.7 0.0 6.9e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain zf-C2H2 PF00096.26 RJW69569.1 - 4.5e-05 23.7 12.2 0.051 14.0 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW69569.1 - 0.014 16.1 11.1 0.61 11.1 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW69569.1 - 3.5 7.5 9.7 0.31 10.8 0.3 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type TTL PF03133.15 RJW69570.1 - 5.8e-67 225.9 0.0 1.1e-66 225.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RJW69570.1 - 0.0041 16.4 0.0 0.029 13.6 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp SIL1 PF16782.5 RJW69571.1 - 0.0012 18.1 0.1 0.0028 16.9 0.0 1.6 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 SLED PF12140.8 RJW69571.1 - 0.036 14.6 0.0 0.18 12.3 0.0 2.1 2 1 1 3 3 3 0 SLED domain zf-H2C2_2 PF13465.6 RJW69572.1 - 3.6e-13 49.3 8.9 3e-08 33.7 2.6 4.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 RJW69572.1 - 7.7e-11 41.8 33.4 5.8e-06 26.5 0.6 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW69572.1 - 1.7e-06 28.4 28.8 0.0033 18.1 0.6 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW69572.1 - 0.015 15.5 4.4 6.6 7.1 0.6 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW69572.1 - 0.017 15.5 4.9 13 6.3 0.7 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 RJW69572.1 - 0.02 15.0 1.4 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger Zn-C2H2_12 PF18112.1 RJW69572.1 - 0.043 14.3 3.3 2.3 8.8 1.0 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 RJW69572.1 - 0.57 10.3 18.2 0.39 10.8 3.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Ribosomal_L29e PF01779.17 RJW69573.1 - 3.9e-23 81.5 8.7 3.9e-23 81.5 8.7 1.9 2 0 0 2 2 2 1 Ribosomal L29e protein family NAD_binding_2 PF03446.15 RJW69575.1 - 2.9e-44 151.0 0.0 4.2e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 RJW69575.1 - 5.1e-37 126.8 0.0 8.6e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 RJW69575.1 - 2.9e-07 30.5 0.0 5.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 RJW69575.1 - 4.3e-05 22.9 0.0 6.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RJW69575.1 - 4.5e-05 24.0 0.0 0.00023 21.7 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 RJW69575.1 - 0.00054 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 RJW69575.1 - 0.004 16.8 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 RJW69575.1 - 0.011 16.2 0.0 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 RJW69575.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 RJW69575.1 - 0.019 15.2 0.0 0.41 10.9 0.0 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 RJW69575.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 RJW69575.1 - 0.19 11.8 0.0 0.37 10.8 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LRR_4 PF12799.7 RJW69578.1 - 2.1e-09 37.5 3.2 0.0027 18.1 0.0 4.0 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW69578.1 - 0.00011 21.8 0.2 0.00096 18.7 0.2 2.3 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RJW69578.1 - 0.00013 21.6 3.9 0.0038 17.0 0.6 3.4 3 0 0 3 3 3 1 Leucine rich repeat TMEM89 PF15098.6 RJW69578.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 TMEM89 protein family LRR_6 PF13516.6 RJW69578.1 - 0.47 10.6 2.3 49 4.3 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Cadherin PF00028.17 RJW69579.1 - 2e-45 153.2 4.4 7.9e-17 61.5 0.1 9.8 8 3 0 8 8 8 6 Cadherin domain Cadherin_2 PF08266.12 RJW69579.1 - 0.014 15.2 1.7 2.9 7.8 0.0 4.3 5 0 0 5 5 5 0 Cadherin-like Tetraspanin PF00335.20 RJW69579.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family Ribosomal_S13 PF00416.22 RJW69580.1 - 3.8e-53 179.3 3.2 4.4e-53 179.1 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Period_C PF12114.8 RJW69580.1 - 0.11 12.1 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Synaphin PF05835.12 RJW69581.1 - 3.2e-13 50.2 2.9 4.3e-13 49.8 2.9 1.2 1 0 0 1 1 1 1 Synaphin protein Zmiz1_N PF18028.1 RJW69581.1 - 0.041 14.2 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Zmiz1 N-terminal tetratricopeptide repeat domain Med21 PF11221.8 RJW69581.1 - 0.61 10.3 5.3 1 9.6 5.1 1.4 1 1 0 1 1 1 0 Subunit 21 of Mediator complex RhoGAP PF00620.27 RJW69582.1 - 1.7e-39 135.1 0.5 3.2e-39 134.2 0.2 1.6 2 0 0 2 2 2 1 RhoGAP domain bZIP_2 PF07716.15 RJW69583.1 - 5.9e-08 32.7 8.8 1.3e-07 31.6 8.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Tektin PF03148.14 RJW69584.1 - 5e-108 361.3 42.5 5.8e-108 361.1 42.5 1.0 1 0 0 1 1 1 1 Tektin family MMTV_SAg PF01054.17 RJW69584.1 - 0.59 9.7 5.4 3.6 7.1 1.9 2.4 2 0 0 2 2 2 0 Mouse mammary tumour virus superantigen AAL_decarboxy PF03306.13 RJW69584.1 - 0.6 9.4 2.8 0.66 9.3 0.1 2.3 2 1 1 3 3 3 0 Alpha-acetolactate decarboxylase DUF812 PF05667.11 RJW69584.1 - 0.97 8.2 37.5 0.0063 15.5 10.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF812) DUF641 PF04859.12 RJW69584.1 - 1.1 9.7 25.8 0.036 14.4 6.2 3.5 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) PUB_1 PF18486.1 RJW69584.1 - 4.3 7.3 5.9 0.73 9.7 0.6 2.4 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain Syntaxin-6_N PF09177.11 RJW69584.1 - 8.1 7.1 27.7 0.5 11.0 4.0 4.8 3 1 0 3 3 3 0 Syntaxin 6, N-terminal CPSase_L_D2 PF02786.17 RJW69586.1 - 4.5e-71 238.7 0.0 7.1e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RJW69586.1 - 2.4e-42 143.9 1.4 3.7e-40 136.9 0.0 2.8 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RJW69586.1 - 2e-32 111.5 0.0 5.4e-32 110.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 RJW69586.1 - 4.7e-16 58.4 0.1 9.6e-16 57.4 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 RJW69586.1 - 2e-11 43.8 0.0 5.5e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 RJW69586.1 - 9.4e-10 38.2 0.0 0.0026 17.6 0.0 2.9 2 0 0 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 RJW69586.1 - 3.2e-08 33.3 0.0 5.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 RJW69586.1 - 2.3e-05 23.7 0.0 0.16 11.2 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 RJW69586.1 - 2.3e-05 24.1 0.0 0.00032 20.4 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 RJW69586.1 - 0.00014 22.6 0.1 0.46 11.2 0.0 3.0 1 1 1 2 2 2 2 HlyD family secretion protein ATPgrasp_ST PF14397.6 RJW69586.1 - 0.00037 19.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 RJW69586.1 - 0.0017 18.4 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PYNP_C PF07831.13 RJW69586.1 - 0.1 12.2 0.0 2.1 8.1 0.0 2.6 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain GTP_EFTU PF00009.27 RJW69587.1 - 1.8e-63 213.6 0.1 2.7e-63 213.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 RJW69587.1 - 7.8e-34 116.1 0.2 3.4e-33 114.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 RJW69587.1 - 2.6e-20 72.2 0.0 7.3e-20 70.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RJW69587.1 - 2e-13 50.5 0.0 6.7e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 RJW69587.1 - 2.6e-13 49.9 0.0 6.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 RJW69587.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RJW69587.1 - 0.099 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MOZ_SAS PF01853.18 RJW69588.1 - 6.8e-81 270.2 0.1 9.8e-81 269.7 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RJW69588.1 - 1.5e-23 82.1 4.2 3.8e-23 80.8 4.2 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 RJW69588.1 - 5.6e-17 61.4 0.1 1.1e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-BED PF02892.15 RJW69588.1 - 0.015 15.3 0.8 0.036 14.1 0.8 1.7 1 0 0 1 1 1 0 BED zinc finger Acetyltransf_7 PF13508.7 RJW69588.1 - 0.016 15.6 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RJW69588.1 - 0.032 14.5 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-met PF12874.7 RJW69588.1 - 0.96 9.9 3.9 0.42 11.1 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 RJW69588.1 - 6.9 7.8 7.3 6 8.0 4.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger AadA_C PF18280.1 RJW69589.1 - 0.044 13.9 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside adenyltransferase C-terminal domain Ribo_biogen_C PF04034.13 RJW69590.1 - 6.8e-48 161.6 0.0 1.1e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal Methyltransf_23 PF13489.6 RJW69590.1 - 5.8e-16 58.8 0.0 9.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RJW69590.1 - 4.3e-13 49.9 0.1 1.3e-12 48.3 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW69590.1 - 4.5e-11 43.3 0.3 4.2e-09 37.0 0.3 2.9 1 1 0 1 1 1 1 Methyltransferase domain RLI PF04068.15 RJW69590.1 - 3.5e-10 39.5 0.0 1.1e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI Methyltransf_11 PF08241.12 RJW69590.1 - 2.9e-08 34.2 0.4 1.5e-06 28.7 0.4 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW69590.1 - 6.8e-07 29.2 0.0 3e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RJW69590.1 - 5.9e-05 22.5 0.0 0.0012 18.2 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 RJW69590.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Baculo_PEP_C PF04513.12 RJW69593.1 - 4.6e-05 23.5 22.2 0.084 12.9 3.8 3.5 1 1 1 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Sun2_CC2 PF18580.1 RJW69593.1 - 0.00041 20.5 2.5 0.00041 20.5 2.5 3.5 2 1 1 3 3 3 1 SUN2 coiled coil domain 2 DUF1664 PF07889.12 RJW69593.1 - 0.0051 16.8 30.2 0.14 12.2 8.0 4.4 2 2 2 4 4 4 2 Protein of unknown function (DUF1664) Viral_P18 PF04521.13 RJW69593.1 - 0.018 14.8 0.2 0.018 14.8 0.2 2.4 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein SF-assemblin PF06705.11 RJW69593.1 - 0.031 13.6 35.2 0.13 11.6 3.8 3.1 1 1 2 3 3 3 0 SF-assemblin/beta giardin IFT57 PF10498.9 RJW69593.1 - 0.047 12.7 30.7 0.17 10.8 6.1 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Apolipoprotein PF01442.18 RJW69593.1 - 0.075 12.9 39.0 1.5 8.7 8.1 3.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain AATF-Che1 PF13339.6 RJW69593.1 - 0.1 13.3 22.9 8.7e+03 -2.7 22.9 3.4 1 1 0 1 1 0 0 Apoptosis antagonizing transcription factor Tup_N PF08581.10 RJW69593.1 - 0.11 12.8 0.5 0.11 12.8 0.5 5.7 1 1 5 6 6 6 0 Tup N-terminal TAF6_C PF07571.13 RJW69593.1 - 0.34 11.3 1.3 16 5.9 0.1 3.3 3 1 1 4 4 4 0 TAF6 C-terminal HEAT repeat domain ApoO PF09769.9 RJW69593.1 - 1.1 9.2 11.8 5.2 7.0 0.3 4.4 1 1 4 5 5 5 0 Apolipoprotein O DUF948 PF06103.11 RJW69593.1 - 1.2 9.5 21.2 3.1 8.1 2.0 4.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AI-2E_transport PF01594.16 RJW69593.1 - 1.8 7.6 7.0 5.5 6.1 1.2 2.6 1 1 2 3 3 3 0 AI-2E family transporter Filament PF00038.21 RJW69593.1 - 2.1 7.8 41.7 0.62 9.6 7.1 3.4 1 1 0 2 2 2 0 Intermediate filament protein DUF16 PF01519.16 RJW69593.1 - 2.8 8.5 30.9 0.069 13.6 6.7 3.7 1 1 2 4 4 4 0 Protein of unknown function DUF16 Vps51 PF08700.11 RJW69593.1 - 3.2 7.9 22.2 8.6 6.5 6.9 5.7 1 1 3 5 5 5 0 Vps51/Vps67 Fib_alpha PF08702.10 RJW69593.1 - 3.5 7.8 31.6 7.3 6.8 8.5 3.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 RJW69593.1 - 3.9 7.8 32.5 3.6 7.9 11.8 3.4 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) PMC2NT PF08066.12 RJW69593.1 - 4.5 8.0 17.3 0.98 10.2 1.5 4.1 1 1 2 4 4 4 0 PMC2NT (NUC016) domain Fez1 PF06818.15 RJW69593.1 - 4.8 7.6 36.9 8.5 6.8 11.3 2.8 1 1 2 3 3 3 0 Fez1 Golgin_A5 PF09787.9 RJW69593.1 - 5.4 6.4 43.0 2.9 7.3 15.6 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 Atg14 PF10186.9 RJW69593.1 - 7.7 5.5 19.4 55 2.7 19.5 2.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF883 PF05957.13 RJW69593.1 - 7.9 7.2 19.5 22 5.7 1.3 4.9 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) Mito_carr PF00153.27 RJW69594.1 - 4.7e-63 209.1 0.3 2e-21 75.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DNA_pol3_delta2 PF13177.6 RJW69595.1 - 1.4e-08 34.6 0.1 3.1e-08 33.6 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 RJW69595.1 - 4.9e-07 29.9 0.0 7.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 RJW69595.1 - 7.6e-06 26.4 2.2 0.00014 22.3 0.1 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 RJW69595.1 - 0.00022 21.6 0.0 0.00054 20.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RJW69595.1 - 0.0036 17.6 0.8 0.0096 16.2 0.2 2.0 2 2 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 RJW69595.1 - 0.0075 16.7 0.7 0.02 15.3 0.0 2.1 3 0 0 3 3 2 1 Replication factor C C-terminal domain AAA_24 PF13479.6 RJW69595.1 - 0.016 14.9 0.1 0.049 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 RJW69595.1 - 0.019 14.7 0.1 0.028 14.2 0.1 1.3 1 1 0 1 1 1 0 AAA domain mRNA_stabil PF13929.6 RJW69595.1 - 0.041 12.9 0.1 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 mRNA stabilisation DUF2075 PF09848.9 RJW69595.1 - 0.055 12.7 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 RJW69595.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DNA_pol3_delta PF06144.13 RJW69595.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Bac_DnaA PF00308.18 RJW69595.1 - 0.15 11.9 0.6 0.88 9.4 0.2 2.4 3 1 0 3 3 3 0 Bacterial dnaA protein PLAT PF01477.23 RJW69596.1 - 4.4e-195 636.7 13.5 1.3e-20 74.1 0.2 17.9 15 3 1 16 16 16 15 PLAT/LH2 domain TENA_THI-4 PF03070.16 RJW69596.1 - 0.21 11.4 0.0 18 5.1 0.0 2.7 3 0 0 3 3 3 0 TENA/THI-4/PQQC family zf-CCHC_5 PF14787.6 RJW69597.1 - 0.0042 16.8 0.3 0.0042 16.8 0.3 1.9 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-C4 PF00105.18 RJW69599.1 - 3.3e-14 53.1 8.5 7.8e-14 51.9 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF4687 PF15747.5 RJW69599.1 - 0.31 11.5 2.0 0.35 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) Sulfate_transp PF00916.20 RJW69600.1 - 8.1e-105 350.7 19.3 1.1e-104 350.2 19.3 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 RJW69600.1 - 2.6e-17 62.6 0.0 5.6e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 STAS domain INCENP_ARK-bind PF03941.15 RJW69600.1 - 0.098 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Tim17 PF02466.19 RJW69600.1 - 0.12 12.8 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family SKA2 PF16740.5 RJW69600.1 - 0.36 10.6 3.4 5.7 6.8 0.0 2.7 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Cu2_monoox_C PF03712.15 RJW69602.1 - 5.1e-27 94.3 0.1 7.8e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 RJW69602.1 - 8.6e-18 64.8 0.3 1.6e-17 63.9 0.3 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain MutS_V PF00488.21 RJW69603.1 - 1.2e-60 204.7 0.0 2.3e-60 203.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RJW69603.1 - 2.8e-33 115.8 0.1 4.5e-33 115.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 RJW69603.1 - 5.5e-12 45.9 0.0 9.5e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV Arm PF00514.23 RJW69604.1 - 2.8e-17 62.1 19.3 1.9e-06 27.7 0.2 6.4 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RJW69604.1 - 0.00076 19.0 0.2 0.0022 17.5 0.1 1.8 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.6 RJW69604.1 - 0.008 16.5 2.7 0.074 13.5 0.3 3.5 3 1 0 3 3 3 1 HEAT repeats ESF1 PF18209.1 RJW69604.1 - 0.083 12.8 0.5 0.23 11.4 0.5 1.8 1 0 0 1 1 1 0 Embryo surrounding factor 1 DUF2520 PF10728.9 RJW69604.1 - 0.13 12.0 1.3 8.7 6.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) HEAT PF02985.22 RJW69604.1 - 1.6 9.2 6.2 3.4 8.2 0.2 4.2 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 RJW69604.1 - 3.3 8.3 7.2 58 4.3 0.3 4.2 5 0 0 5 5 5 0 HEAT-like repeat C2 PF00168.30 RJW69605.1 - 1.2e-41 141.2 0.0 1.5e-19 70.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 RJW69605.1 - 4.1e-21 75.4 10.3 1.1e-13 51.5 5.7 2.3 2 0 0 2 2 2 2 FYVE-type zinc finger FYVE PF01363.21 RJW69605.1 - 0.0018 18.4 10.0 0.0052 16.9 10.0 1.8 1 1 0 1 1 1 1 FYVE zinc finger Prok-RING_2 PF14445.6 RJW69605.1 - 0.45 10.7 3.5 1 9.6 3.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-RING_2 PF13639.6 RJW69605.1 - 0.69 10.3 8.1 0.14 12.5 3.5 2.1 2 0 0 2 2 2 0 Ring finger domain C1_1 PF00130.22 RJW69605.1 - 2.6 8.0 7.5 1.6 8.7 4.4 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HTH_32 PF13565.6 RJW69605.1 - 2.7 8.7 8.2 0.86 10.3 2.8 2.6 2 0 0 2 2 2 0 Homeodomain-like domain zf-piccolo PF05715.13 RJW69605.1 - 3.3 7.9 8.2 0.83 9.8 4.3 2.0 2 0 0 2 2 2 0 Piccolo Zn-finger Cadherin PF00028.17 RJW69606.1 - 1e-54 183.0 7.6 9e-13 48.5 0.4 7.8 5 2 1 6 6 6 5 Cadherin domain Cadherin_2 PF08266.12 RJW69606.1 - 0.0011 18.7 0.2 1.1 9.1 0.1 4.1 4 0 0 4 4 4 1 Cadherin-like Invasin_D3 PF09134.10 RJW69606.1 - 0.091 13.1 3.1 55 4.2 0.0 4.0 4 0 0 4 4 4 0 Invasin, domain 3 DUF2721 PF11026.8 RJW69608.1 - 0.022 14.7 4.8 0.029 14.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Chitin_synth_2 PF03142.15 RJW69608.1 - 0.061 11.9 0.9 0.075 11.6 0.9 1.0 1 0 0 1 1 1 0 Chitin synthase RCR PF12273.8 RJW69608.1 - 0.15 12.8 1.8 0.41 11.3 0.2 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF2207 PF09972.9 RJW69608.1 - 0.21 10.3 2.1 0.25 10.1 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LptF_LptG PF03739.14 RJW69608.1 - 0.55 9.0 4.3 0.71 8.7 4.3 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Glyco_hydro_47 PF01532.20 RJW69610.1 - 3.1e-98 329.6 0.0 7.6e-98 328.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 RJW69610.1 - 2e-06 27.7 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 PA domain DEAD_2 PF06733.15 RJW69611.1 - 6.2e-49 166.0 0.1 1.2e-48 165.1 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 RJW69611.1 - 5.5e-41 140.6 0.0 1.2e-40 139.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 RJW69611.1 - 7.9e-39 133.3 0.6 2.9e-35 121.7 0.1 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain RVT_1 PF00078.27 RJW69611.1 - 1.8e-19 70.2 0.0 3.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ResIII PF04851.15 RJW69611.1 - 6.3e-05 23.0 0.0 0.00093 19.2 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 RJW69611.1 - 0.042 13.3 0.0 5.8 6.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 RJW69611.1 - 0.17 12.2 0.1 34 4.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain SURF4 PF02077.15 RJW69612.1 - 7.7e-98 327.3 8.6 8.7e-98 327.2 8.6 1.0 1 0 0 1 1 1 1 SURF4 family EloA-BP1 PF15870.5 RJW69614.1 - 2.8e-11 44.0 0.1 5.1e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 ElonginA binding-protein 1 RNase_T PF00929.24 RJW69614.1 - 0.0034 17.9 0.1 0.012 16.2 0.1 1.9 1 1 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 RJW69614.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.5 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like ATP-synt_8 PF00895.20 RJW69614.1 - 0.029 14.8 1.6 0.061 13.8 1.6 1.4 1 0 0 1 1 1 0 ATP synthase protein 8 LRRNT_2 PF08263.12 RJW69615.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain COX5B PF01215.19 RJW69616.1 - 0.00018 21.2 0.1 0.0002 21.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb FHA PF00498.26 RJW69617.1 - 8.2e-14 51.7 0.0 1.9e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Peptidase_M16_M PF16187.5 RJW69619.1 - 1.3e-60 205.1 2.2 2.1e-60 204.4 2.2 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 RJW69619.1 - 1.1e-25 90.8 0.0 2.3e-16 60.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RJW69619.1 - 6.8e-17 61.8 0.0 1.5e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) E1_DerP2_DerF2 PF02221.15 RJW69620.1 - 2.3e-10 41.0 0.0 2.4e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 ML domain zf-Di19 PF05605.12 RJW69621.1 - 5.9e-05 23.3 4.5 0.012 15.8 0.2 1.8 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-SNAP50_C PF12251.8 RJW69621.1 - 0.0035 17.0 1.1 0.0042 16.8 1.1 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C2H2_4 PF13894.6 RJW69621.1 - 0.027 15.3 1.9 0.13 13.2 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger NOB1_Zn_bind PF08772.11 RJW69621.1 - 0.062 13.5 0.4 0.14 12.3 0.0 1.8 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Cys_rich_KTR PF14205.6 RJW69621.1 - 0.066 13.0 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Cysteine-rich KTR E1_DerP2_DerF2 PF02221.15 RJW69622.1 - 1.4e-15 57.9 0.0 1.6e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 ML domain Acid_PPase PF12689.7 RJW69623.1 - 1.5e-25 90.0 0.0 1.9e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Acid Phosphatase Pollen_allerg_1 PF01357.21 RJW69624.1 - 0.021 14.8 0.9 0.026 14.5 0.9 1.1 1 0 0 1 1 1 0 Pollen allergen HRI1 PF16815.5 RJW69625.1 - 0.04 13.6 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein HRI1 Helicase_C PF00271.31 RJW69626.1 - 1.8e-27 95.9 0.0 6e-26 91.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RJW69626.1 - 7.8e-11 42.1 0.0 1.7e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RJW69626.1 - 0.083 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Phosphodiest PF01663.22 RJW69627.1 - 2.2e-57 195.3 0.6 5.6e-57 193.9 0.6 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RVT_1 PF00078.27 RJW69627.1 - 4.2e-15 55.9 0.0 1e-14 54.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PglZ PF08665.12 RJW69627.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 PglZ domain NPDC1 PF06809.11 RJW69627.1 - 0.14 11.2 0.2 0.34 9.9 0.1 1.7 2 0 0 2 2 2 0 Neural proliferation differentiation control-1 protein (NPDC1) HemY_N PF07219.13 RJW69627.1 - 0.18 12.0 0.4 0.44 10.8 0.4 1.6 1 0 0 1 1 1 0 HemY protein N-terminus FOXP-CC PF16159.5 RJW69628.1 - 0.061 14.0 4.5 2.6 8.7 0.9 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain E1_DerP2_DerF2 PF02221.15 RJW69629.1 - 1.1e-13 51.8 0.0 2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 ML domain DBC1 PF14443.6 RJW69629.1 - 1.1e-07 31.8 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 DBC1 DUF5641 PF18701.1 RJW69629.1 - 0.0092 16.1 0.2 0.016 15.3 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Raptor_N PF14538.6 RJW69630.1 - 1.4e-43 148.4 0.0 3.1e-43 147.2 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 RJW69630.1 - 0.00037 20.5 0.1 0.024 14.9 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 RJW69630.1 - 0.01 16.2 0.0 0.045 14.1 0.0 2.1 1 0 0 1 1 1 0 HEAT repeats Cwf_Cwc_15 PF04889.12 RJW69630.1 - 1.2 8.8 17.6 2.6 7.7 17.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-CW PF07496.15 RJW69631.1 - 0.0015 18.5 2.3 0.0028 17.6 2.3 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger E1_DerP2_DerF2 PF02221.15 RJW69633.1 - 4.5e-10 40.1 0.1 7.6e-10 39.3 0.1 1.4 1 1 0 1 1 1 1 ML domain Haspin_kinase PF12330.8 RJW69634.1 - 6.4e-57 193.2 0.0 9.8e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_Tyr PF07714.17 RJW69634.1 - 2e-05 24.0 0.0 6.5e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW69634.1 - 0.0066 15.9 0.0 0.059 12.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Brix PF04427.18 RJW69636.1 - 3.9e-34 118.5 0.0 8e-33 114.2 0.0 2.2 1 1 0 1 1 1 1 Brix domain NIPSNAP PF07978.13 RJW69636.1 - 0.087 13.1 3.2 0.62 10.3 0.0 2.8 2 1 0 2 2 2 0 NIPSNAP E1_DerP2_DerF2 PF02221.15 RJW69637.1 - 2.3e-12 47.5 0.0 2.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 RJW69638.1 - 1.1e-17 64.7 0.1 1.3e-17 64.5 0.1 1.0 1 0 0 1 1 1 1 ML domain Ank_2 PF12796.7 RJW69640.1 - 4.5e-20 72.0 0.1 1.2e-10 41.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RJW69640.1 - 4.4e-18 64.8 2.6 2.2e-05 24.7 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RJW69640.1 - 3.3e-17 62.6 0.7 3.7e-09 37.0 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW69640.1 - 1.4e-15 57.1 1.6 1.7e-06 28.2 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW69640.1 - 2.2e-13 49.1 0.4 0.00047 20.4 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat PRKG1_interact PF15898.5 RJW69640.1 - 1.6e-07 32.2 2.9 1.6e-07 32.2 2.9 3.5 3 0 0 3 3 3 1 cGMP-dependent protein kinase interacting domain Paf67 PF10255.9 RJW69641.1 - 1.1e-146 489.0 0.2 1.4e-146 488.6 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 DUF2428 PF10350.9 RJW69641.1 - 0.057 12.7 0.3 4.5 6.5 0.0 2.2 1 1 1 2 2 2 0 Putative death-receptor fusion protein (DUF2428) LegC3_N PF18654.1 RJW69642.1 - 0.17 11.1 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain RVT_1 PF00078.27 RJW69644.1 - 2e-17 63.4 0.0 4.1e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sds3 PF08598.11 RJW69644.1 - 5.1e-13 49.5 0.0 8.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Sds3-like RseC_MucC PF04246.12 RJW69644.1 - 5.9 6.8 6.0 6.5 6.7 4.1 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1640 PF07798.11 RJW69644.1 - 6.4 6.8 8.2 13 5.8 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) RVT_1 PF00078.27 RJW69645.1 - 5.6e-45 153.5 0.0 1.5e-44 152.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_2 PF07724.14 RJW69645.1 - 4.4e-43 147.3 0.0 9.6e-43 146.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank PF00023.30 RJW69645.1 - 4.5e-12 45.8 0.1 0.00025 21.3 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RJW69645.1 - 6e-10 38.5 0.1 0.00086 19.6 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 RJW69645.1 - 1.8e-09 38.1 0.0 0.00012 22.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) AAA_5 PF07728.14 RJW69645.1 - 4.8e-09 36.3 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank_5 PF13857.6 RJW69645.1 - 7.5e-07 29.3 0.1 0.00052 20.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) ClpB_D2-small PF10431.9 RJW69645.1 - 4.9e-06 26.5 0.0 1.4e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 RJW69645.1 - 5.3e-06 26.9 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_4 PF13637.6 RJW69645.1 - 4.1e-05 24.0 0.0 0.005 17.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Sigma54_activat PF00158.26 RJW69645.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 RJW69645.1 - 0.00039 20.9 0.1 0.0049 17.3 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain Torsin PF06309.11 RJW69645.1 - 0.001 19.2 0.0 0.0038 17.3 0.0 2.0 2 0 0 2 2 1 1 Torsin Zeta_toxin PF06414.12 RJW69645.1 - 0.0037 16.6 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 RJW69645.1 - 0.0051 17.1 0.1 0.043 14.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 RJW69645.1 - 0.017 15.0 0.0 0.059 13.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) YchF-GTPase_C PF06071.13 RJW69645.1 - 0.041 14.1 0.1 0.094 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF933) ATPase_2 PF01637.18 RJW69645.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 RJW69645.1 - 0.055 13.2 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RJW69645.1 - 0.084 13.4 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 RJW69645.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 RJW69645.1 - 0.18 11.3 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Pkinase_Tyr PF07714.17 RJW69646.1 - 3e-73 246.3 0.0 1.3e-60 204.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW69646.1 - 1.2e-31 110.1 0.0 2.2e-28 99.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Recep_L_domain PF01030.24 RJW69646.1 - 2.2e-28 98.6 0.0 1.5e-19 70.1 0.0 2.6 2 0 0 2 2 2 2 Receptor L domain Furin-like PF00757.20 RJW69646.1 - 1e-21 77.4 34.2 6e-21 74.9 34.2 2.4 1 1 0 1 1 1 1 Furin-like cysteine rich region fn3 PF00041.21 RJW69646.1 - 8e-06 26.1 9.5 0.82 10.1 0.1 5.5 5 0 0 5 5 5 2 Fibronectin type III domain Kinase-like PF14531.6 RJW69646.1 - 0.0039 16.5 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Fimbrillin_C PF15495.6 RJW69646.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal PRKG1_interact PF15898.5 RJW69649.1 - 2.6e-07 31.5 0.4 4.4e-07 30.8 0.4 1.3 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain DUF4140 PF13600.6 RJW69649.1 - 0.018 15.5 0.1 0.027 14.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) YL1 PF05764.13 RJW69652.1 - 0.04 14.0 2.8 0.044 13.9 2.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 RJW69652.1 - 0.61 9.5 8.6 0.7 9.3 8.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RJW69652.1 - 0.87 7.7 7.4 0.95 7.6 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RJW69652.1 - 0.9 8.8 7.5 1.2 8.4 7.5 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RJW69652.1 - 8 4.4 16.1 10 4.1 16.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Roughex PF06020.11 RJW69652.1 - 9.8 5.2 12.7 2.6 7.1 9.1 1.7 1 1 1 2 2 2 0 Drosophila roughex protein JAB PF01398.21 RJW69653.1 - 9.1e-18 64.4 0.2 2.3e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 RJW69653.1 - 6.3e-10 39.2 0.8 6.3e-10 39.2 0.8 1.7 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 RJW69653.1 - 4.6e-06 26.4 0.8 9.6e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain DUF3987 PF13148.6 RJW69653.1 - 0.025 13.6 6.2 0.038 13.0 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CAS_C PF12026.8 RJW69653.1 - 0.17 11.9 1.6 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain DUF5401 PF17380.2 RJW69653.1 - 0.63 8.0 10.7 0.84 7.6 10.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Galactosyl_T PF01762.21 RJW69654.1 - 9.5e-44 149.6 0.1 1.3e-43 149.1 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase DENN PF02141.21 RJW69655.1 - 4.8e-38 131.0 1.6 1.8e-37 129.1 1.6 2.0 1 1 0 1 1 1 1 DENN (AEX-3) domain RUN PF02759.19 RJW69655.1 - 7.2e-24 84.3 7.1 1.6e-13 50.8 4.7 3.7 2 2 0 2 2 2 2 RUN domain dDENN PF03455.19 RJW69655.1 - 3.4e-11 42.9 0.3 1.1e-10 41.4 0.3 1.9 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 RJW69655.1 - 1.8e-10 41.4 0.2 6.4e-10 39.6 0.2 2.1 1 0 0 1 1 1 1 uDENN domain PLAT PF01477.23 RJW69655.1 - 1.2e-09 38.8 0.0 2.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain SUIM_assoc PF16619.5 RJW69655.1 - 2.7 8.1 6.1 0.26 11.4 0.3 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Glyco_hydro_59 PF02057.15 RJW69656.1 - 1.3e-83 280.6 3.3 1.4e-49 168.9 1.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 RJW69656.1 - 8.9e-38 129.0 0.0 1.6e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain zf-C2H2 PF00096.26 RJW69657.1 - 0.0001 22.6 28.7 0.0044 17.4 4.4 5.1 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW69657.1 - 0.0036 18.0 25.3 0.0054 17.5 2.9 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW69657.1 - 0.0037 17.2 6.8 0.3 11.1 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW69657.1 - 0.0042 17.4 5.4 0.0042 17.4 5.4 5.4 3 1 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 RJW69657.1 - 0.0062 16.9 2.1 0.013 15.9 0.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RJW69657.1 - 0.026 14.3 0.1 0.026 14.3 0.1 3.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 RJW69657.1 - 1 9.2 19.4 3.4 7.5 2.0 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain DUF629 PF04780.12 RJW69657.1 - 2 6.9 6.2 3.9 5.9 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 RJW69657.1 - 10 6.6 13.0 56 4.2 10.8 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) STT3 PF02516.14 RJW69658.1 - 1.2e-14 54.1 0.5 1.3e-14 54.0 0.5 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Asp PF00026.23 RJW69659.1 - 2.1e-28 99.6 0.0 2.5e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF5539 PF17693.1 RJW69659.1 - 0.053 13.2 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) RVT_1 PF00078.27 RJW69661.1 - 0.00022 20.8 0.0 0.00053 19.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 RJW69661.1 - 0.0003 21.0 0.2 0.0003 21.0 0.2 2.6 2 0 0 2 2 2 1 GIY-YIG catalytic domain SUIM_assoc PF16619.5 RJW69661.1 - 0.045 13.8 4.0 0.12 12.5 4.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF1438 PF07270.11 RJW69661.1 - 0.11 12.6 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1438) RBB1NT PF08169.11 RJW69661.1 - 0.16 12.1 0.6 0.38 10.9 0.6 1.6 1 0 0 1 1 1 0 RBB1NT (NUC162) domain F-box-like_2 PF13013.6 RJW69662.1 - 0.025 14.5 0.0 9.6 6.2 0.0 2.2 2 0 0 2 2 2 0 F-box-like domain Cadherin PF00028.17 RJW69664.1 - 6.4e-23 81.0 0.1 8.5e-07 29.3 0.0 4.5 4 0 0 4 4 4 4 Cadherin domain Agouti PF05039.12 RJW69664.1 - 0.071 13.8 0.2 0.071 13.8 0.2 2.0 2 0 0 2 2 2 0 Agouti protein EphA2_TM PF14575.6 RJW69664.1 - 0.24 12.3 1.4 0.55 11.1 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SNARE PF05739.19 RJW69665.1 - 5.5e-10 39.1 3.1 5.5e-10 39.1 3.1 2.6 2 1 1 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 RJW69665.1 - 9e-05 22.8 3.8 9e-05 22.8 3.8 2.9 2 1 1 3 3 3 1 Syntaxin-like protein ETRAMP PF09716.10 RJW69665.1 - 0.028 14.5 0.0 0.081 13.0 0.0 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4988 PF16378.5 RJW69665.1 - 0.07 12.8 0.5 0.15 11.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function Orf78 PF06024.12 RJW69665.1 - 0.11 12.9 0.8 0.19 12.0 0.8 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Laminin_G_3 PF13385.6 RJW69666.1 - 0.0012 19.0 0.0 0.032 14.4 0.0 2.3 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 RJW69666.1 - 0.003 16.8 0.1 0.003 16.8 0.1 4.7 5 1 1 6 6 6 3 Domain of unknown function (DUF4704) DUF1322 PF07032.11 RJW69666.1 - 0.13 12.8 0.1 0.31 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) Amidase PF01425.21 RJW69668.1 - 1.5e-83 281.3 0.0 2.1e-83 280.8 0.0 1.2 1 0 0 1 1 1 1 Amidase Lipase_3 PF01764.25 RJW69669.1 - 1.3e-11 44.5 0.0 1.2e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Hydrolase_4 PF12146.8 RJW69669.1 - 0.00017 20.9 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_C42 PF05533.12 RJW69669.1 - 0.019 15.0 0.0 0.51 10.4 0.0 2.7 2 0 0 2 2 2 0 Beet yellows virus-type papain-like endopeptidase C42 Abhydrolase_3 PF07859.13 RJW69669.1 - 0.057 13.3 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-C3HC4_2 PF13923.6 RJW69671.1 - 9e-12 44.6 8.3 4.1e-11 42.5 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW69671.1 - 1.8e-10 40.9 7.6 4.3e-10 39.8 6.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 RJW69671.1 - 1.3e-09 37.7 9.6 2.6e-09 36.8 6.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW69671.1 - 3e-09 36.7 11.6 5.6e-09 35.9 10.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RJW69671.1 - 9.3e-08 31.8 4.1 1.9e-07 30.8 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RJW69671.1 - 4.6e-06 26.7 7.9 4.6e-06 26.7 7.9 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RJW69671.1 - 1.7e-05 25.0 11.0 5.5e-05 23.4 8.6 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 RJW69671.1 - 3.6e-05 23.8 0.4 0.0001 22.4 0.0 1.9 2 0 0 2 2 2 1 U-box domain Prok-RING_4 PF14447.6 RJW69671.1 - 5.2e-05 23.0 10.1 0.0008 19.2 9.7 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RJW69671.1 - 0.00018 21.4 5.1 0.00071 19.5 5.2 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 RJW69671.1 - 0.019 15.1 3.5 0.041 14.0 3.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Parathyroid PF01279.17 RJW69671.1 - 0.023 15.3 0.1 0.052 14.2 0.1 1.5 1 0 0 1 1 1 0 Parathyroid hormone family zf-RING_11 PF17123.5 RJW69671.1 - 0.21 11.4 6.2 1.2 8.9 5.6 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-Nse PF11789.8 RJW69671.1 - 0.28 11.0 9.8 0.94 9.3 7.4 2.6 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit UQ_con PF00179.26 RJW69673.1 - 6.9e-17 61.4 0.0 8.1e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RJW69673.1 - 0.17 12.2 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain PMP22_Claudin PF00822.20 RJW69674.1 - 0.00015 21.7 1.8 0.00019 21.3 1.8 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2919 PF11143.8 RJW69674.1 - 0.0079 16.5 0.1 0.014 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2919) DUF5373 PF17343.2 RJW69674.1 - 0.043 13.7 1.3 0.06 13.2 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5373) DUF997 PF06196.12 RJW69674.1 - 1.2 9.2 8.9 0.83 9.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF4689 PF15755.5 RJW69676.1 - 0.083 12.5 0.4 0.11 12.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) MARVEL PF01284.23 RJW69676.1 - 0.12 12.4 14.2 0.17 11.9 14.2 1.3 1 0 0 1 1 1 0 Membrane-associating domain Cation_ATPase_C PF00689.21 RJW69676.1 - 0.23 11.2 7.1 0.35 10.6 7.1 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Pkinase_Tyr PF07714.17 RJW69677.1 - 1.2e-70 237.7 0.0 1.7e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW69677.1 - 2.7e-43 148.3 0.0 4.3e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 RJW69677.1 - 1.2e-17 64.1 0.3 2.2e-17 63.2 0.3 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RJW69677.1 - 0.0014 18.4 0.0 0.0045 16.7 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein Pkinase_Tyr PF07714.17 RJW69679.1 - 5.4e-77 258.6 0.2 4.3e-71 239.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW69679.1 - 1.3e-44 152.6 0.0 1.6e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RJW69679.1 - 2.1e-05 23.7 0.1 6.1e-05 22.1 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RJW69679.1 - 0.00021 20.7 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH2 PF00017.24 RJW69679.1 - 0.011 15.8 0.1 0.027 14.6 0.1 1.7 1 0 0 1 1 1 0 SH2 domain DUF382 PF04037.13 RJW69679.1 - 0.033 14.3 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF382) Kdo PF06293.14 RJW69679.1 - 0.042 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW69679.1 - 0.091 12.7 0.1 0.34 10.8 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 RJW69679.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Virulence_RhuM PF13310.6 RJW69679.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Virulence protein RhuM family Peptidase_M14 PF00246.24 RJW69680.1 - 7.5e-25 88.3 0.0 2.4e-24 86.7 0.0 1.8 1 1 1 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 RJW69680.1 - 1.2e-13 51.4 0.2 4.6e-13 49.5 0.1 2.0 1 1 1 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain TSP_1 PF00090.19 RJW69681.1 - 2.6e-08 33.9 14.8 4.5e-08 33.2 4.2 4.8 5 0 0 5 5 5 3 Thrombospondin type 1 domain BK_channel_a PF03493.18 RJW69682.1 - 5e-25 87.5 0.0 1.1e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ig_3 PF13927.6 RJW69683.1 - 5.9e-37 126.1 1.9 1.7e-07 31.7 0.1 7.2 6 1 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 RJW69683.1 - 1.3e-35 121.4 0.0 8.4e-10 38.6 0.0 7.6 6 3 0 6 6 6 4 Immunoglobulin I-set domain V-set PF07686.17 RJW69683.1 - 1.9e-24 85.9 11.1 0.0025 18.0 0.1 8.6 6 3 1 7 7 7 6 Immunoglobulin V-set domain Ig_2 PF13895.6 RJW69683.1 - 2.9e-23 82.0 2.4 1.3e-06 28.6 0.0 6.9 7 1 0 7 7 6 3 Immunoglobulin domain ig PF00047.25 RJW69683.1 - 1.2e-22 79.9 2.1 3.1e-05 24.0 0.0 5.7 5 1 0 5 5 5 4 Immunoglobulin domain Integrase_H2C2 PF17921.1 RJW69683.1 - 5.5e-10 39.2 0.1 1.3e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Ig_6 PF18452.1 RJW69683.1 - 1.9e-08 33.8 0.7 0.069 12.7 0.0 4.8 5 0 0 5 5 5 3 Immunoglobulin domain Ig_4 PF16680.5 RJW69683.1 - 2e-08 34.4 1.6 0.031 14.5 0.0 4.8 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 RJW69683.1 - 1.3e-07 31.5 0.0 0.13 12.3 0.0 4.5 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 RJW69683.1 - 2.6e-07 30.9 0.4 0.12 12.8 0.0 4.3 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set PF05790.15 RJW69683.1 - 0.0056 16.8 0.0 4 7.7 0.0 3.0 3 0 0 3 3 2 1 Immunoglobulin C2-set domain C1-set PF07654.15 RJW69683.1 - 0.0057 17.0 0.5 1.9 8.9 0.1 3.6 4 0 0 4 4 4 1 Immunoglobulin C1-set domain DUF5623 PF18536.1 RJW69683.1 - 0.027 14.7 0.1 0.077 13.3 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF5623) Receptor_2B4 PF11465.8 RJW69683.1 - 0.33 11.2 6.0 50 4.2 0.0 4.7 5 0 0 5 5 5 0 Natural killer cell receptor 2B4 Zip PF02535.22 RJW69684.1 - 0.12 11.6 3.2 0.13 11.5 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FA_desaturase PF00487.24 RJW69684.1 - 0.33 10.7 3.8 0.38 10.6 3.8 1.1 1 0 0 1 1 1 0 Fatty acid desaturase UL41A PF17591.2 RJW69684.1 - 1.9 8.7 8.4 0.18 11.9 2.3 2.0 1 1 1 2 2 2 0 Herpesvirus UL41A DUF2207 PF09972.9 RJW69684.1 - 2.6 6.7 6.2 2.5 6.8 6.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3040 PF11239.8 RJW69684.1 - 6.2 7.2 8.4 33 4.8 6.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) SUR7 PF06687.12 RJW69684.1 - 7 6.2 12.7 4.8 6.8 11.6 1.2 1 1 0 1 1 1 0 SUR7/PalI family Rsm22 PF09243.10 RJW69685.1 - 8.4e-45 153.2 0.0 1.1e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 RJW69685.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PNISR PF15996.5 RJW69686.1 - 1.3e-45 156.2 0.5 1.3e-45 156.2 0.5 2.9 2 1 1 3 3 3 1 Arginine/serine-rich protein PNISR RTT107_BRCT_5 PF16770.5 RJW69687.1 - 0.00089 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 RJW69687.1 - 0.022 15.1 0.0 0.14 12.6 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 RJW69687.1 - 0.034 14.2 0.0 2 8.5 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 RJW69687.1 - 0.13 12.2 0.0 0.55 10.2 0.0 2.0 2 0 0 2 2 2 0 twin BRCT domain Cmyb_C PF09316.10 RJW69687.1 - 0.24 11.0 3.4 0.22 11.2 0.4 2.5 2 1 0 2 2 2 0 C-myb, C-terminal DUF1344 PF07076.11 RJW69688.1 - 0.022 14.7 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) HET PF06985.11 RJW69688.1 - 0.14 12.5 0.0 13 6.1 0.0 2.2 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) DUF282 PF03380.14 RJW69688.1 - 0.47 10.4 2.0 25 4.9 0.1 2.4 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 Arm PF00514.23 RJW69689.1 - 1.1e-58 193.6 21.0 2.4e-09 36.9 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 RJW69689.1 - 2.7e-17 63.0 8.5 2.7e-17 63.0 8.5 1.8 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 RJW69689.1 - 7.9e-17 60.6 2.2 3.7e-16 58.4 2.7 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 RJW69689.1 - 2.2e-12 47.2 3.0 0.00098 19.6 0.1 5.2 4 1 1 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 RJW69689.1 - 3.7e-10 40.0 5.5 0.12 12.8 0.0 6.9 2 1 7 9 9 9 3 HEAT repeats HEAT PF02985.22 RJW69689.1 - 8.4e-07 28.7 14.4 0.037 14.3 0.0 7.9 9 0 0 9 9 9 2 HEAT repeat NopRA1 PF16201.5 RJW69689.1 - 6.1e-06 26.0 0.1 0.03 13.9 0.0 3.6 2 1 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Arm_2 PF04826.13 RJW69689.1 - 0.00057 19.4 0.1 1.1 8.6 0.1 3.1 2 1 0 2 2 2 2 Armadillo-like Taxilin PF09728.9 RJW69689.1 - 0.14 11.3 5.5 0.22 10.7 5.5 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF1955 PF09205.10 RJW69689.1 - 0.14 11.9 2.8 2.8 7.7 0.1 3.6 3 1 0 4 4 4 0 Domain of unknown function (DUF1955) Synaptobrevin PF00957.21 RJW69691.1 - 2.4e-17 62.5 0.3 2.4e-17 62.5 0.3 1.5 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 RJW69691.1 - 0.00038 20.4 0.0 0.0008 19.4 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain TMEM51 PF15345.6 RJW69691.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Peptidase_M75 PF09375.10 RJW69691.1 - 0.11 11.9 0.2 0.13 11.7 0.2 1.1 1 0 0 1 1 1 0 Imelysin Phage_GPO PF05929.11 RJW69691.1 - 0.16 11.6 1.9 0.19 11.3 1.9 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Rax2 PF12768.7 RJW69691.1 - 0.2 11.1 1.5 0.24 10.8 1.5 1.4 1 1 0 1 1 1 0 Cortical protein marker for cell polarity adh_short PF00106.25 RJW69693.1 - 1.5e-27 96.4 0.0 3.6e-27 95.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW69693.1 - 7e-22 78.1 0.0 1.2e-21 77.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW69693.1 - 6e-05 23.0 0.3 0.00013 21.9 0.2 1.5 2 0 0 2 2 2 1 KR domain Tsc35 PF15079.6 RJW69693.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Testis-specific protein 35 PolyA_pol_arg_C PF12626.7 RJW69694.1 - 0.015 15.3 0.5 0.026 14.5 0.5 1.3 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus PH PF00169.29 RJW69695.1 - 5.8e-18 65.3 0.0 7.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RJW69695.1 - 1.2e-06 28.9 1.2 1.9e-05 25.0 1.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RJW69695.1 - 0.00016 21.9 0.1 0.0011 19.2 0.0 1.9 1 1 1 2 2 2 1 Pleckstrin homology domain DUF865 PF05906.11 RJW69697.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) DnaJ_C PF01556.18 RJW69698.1 - 1.3e-39 135.6 0.0 1.7e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RJW69698.1 - 8.7e-21 73.8 0.5 1.5e-20 73.1 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain gpUL132 PF11359.8 RJW69699.1 - 0.15 11.5 0.2 0.27 10.7 0.2 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DoxX_2 PF13564.6 RJW69701.1 - 5.5e-07 29.7 0.0 9.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.12 RJW69701.1 - 1.1e-05 25.9 0.4 1.9e-05 25.2 0.4 1.4 1 0 0 1 1 1 1 DoxX DUF308 PF03729.13 RJW69701.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.9 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) SNF PF00209.18 RJW69702.1 - 2e-174 581.1 37.7 2.3e-174 580.9 37.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Mg_trans_NIPA PF05653.14 RJW69703.1 - 0.00024 20.3 6.3 0.00028 20.1 6.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF2207 PF09972.9 RJW69703.1 - 2.5 6.8 7.7 1.7 7.3 6.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 RJW69703.1 - 4.3 7.5 8.6 1.1 9.4 4.2 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase PRA1 PF03208.19 RJW69703.1 - 9.1 5.9 9.1 8.3 6.0 3.5 2.1 1 1 1 2 2 2 0 PRA1 family protein DUF4579 PF15158.6 RJW69706.1 - 0.01 15.6 0.3 0.013 15.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) DUF4029 PF13221.6 RJW69706.1 - 0.032 14.9 2.8 0.034 14.8 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4029) Ank_3 PF13606.6 RJW69708.1 - 4.8e-08 32.7 0.2 0.0021 18.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RJW69708.1 - 9.1e-08 32.2 1.8 0.011 16.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RJW69708.1 - 1.7e-06 28.2 2.3 0.00026 21.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 RJW69708.1 - 4.3e-06 27.2 0.0 1.2e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW69708.1 - 8.6e-06 26.2 0.1 2.3e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) SRAP PF02586.14 RJW69709.1 - 2.8e-44 151.3 0.0 6.5e-39 133.7 0.0 2.2 1 1 1 2 2 2 2 SOS response associated peptidase (SRAP) Pkinase PF00069.25 RJW69710.1 - 1e-24 87.3 0.0 1.8e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69710.1 - 3.3e-17 62.6 0.0 6.2e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW69710.1 - 1.1e-06 28.2 0.1 2.3e-06 27.1 0.1 1.5 1 1 0 1 1 1 1 Kinase-like fn3 PF00041.21 RJW69711.1 - 6e-23 81.0 25.3 0.074 13.4 0.0 13.0 13 1 0 13 13 13 7 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW69711.1 - 1.1e-07 32.4 0.3 4.6 7.9 0.0 6.5 6 1 0 6 6 6 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RJW69711.1 - 0.0016 18.8 0.6 8.4 6.9 0.0 3.9 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 RJW69711.1 - 0.081 13.2 0.6 27 5.2 0.1 3.7 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Ion_trans_2 PF07885.16 RJW69713.1 - 1.2e-13 50.8 1.9 1.2e-13 50.8 1.9 2.5 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 RJW69713.1 - 5.5e-07 29.1 11.9 5.5e-07 29.1 11.9 2.1 3 0 0 3 3 3 1 Ion transport protein Acyl-CoA_dh_1 PF00441.24 RJW69714.1 - 6.3e-40 136.8 0.9 6.3e-40 136.8 0.9 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RJW69714.1 - 6.2e-28 96.9 0.1 1.1e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RJW69714.1 - 6.3e-17 62.3 0.1 2.4e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RJW69714.1 - 2.8e-11 43.8 0.0 4.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 RJW69714.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal MPP6 PF10175.9 RJW69715.1 - 0.0015 19.0 0.1 0.0035 17.9 0.1 1.7 1 1 0 1 1 1 1 M-phase phosphoprotein 6 SOCS_box PF07525.16 RJW69716.1 - 4.4e-06 26.9 0.7 1.4e-05 25.3 0.7 2.0 1 0 0 1 1 1 1 SOCS box TGF_beta PF00019.20 RJW69718.1 - 7.1e-12 46.2 1.9 1.5e-11 45.2 1.9 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain GOLD_2 PF13897.6 RJW69719.1 - 4.2e-48 163.3 0.5 2.5e-47 160.9 0.5 2.3 1 1 0 1 1 1 1 Golgi-dynamics membrane-trafficking Topoisom_I_N PF02919.15 RJW69719.1 - 0.1 12.1 0.3 0.17 11.3 0.3 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Ribosomal_L24e PF01246.20 RJW69719.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L24e adh_short PF00106.25 RJW69720.1 - 9.8e-30 103.5 0.0 1.6e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW69720.1 - 1.7e-20 73.6 0.0 4e-20 72.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW69720.1 - 0.00058 19.8 0.2 0.0011 18.9 0.2 1.4 1 0 0 1 1 1 1 KR domain YlbE PF14003.6 RJW69721.1 - 0.046 14.2 0.1 0.072 13.5 0.1 1.3 1 0 0 1 1 1 0 YlbE-like protein 7tm_1 PF00001.21 RJW69722.1 - 1.6e-46 158.8 19.9 1.6e-46 158.8 19.9 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW69722.1 - 1.8e-14 53.7 16.4 3.6e-14 52.8 16.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RJW69722.1 - 1e-13 51.3 20.5 1.9e-12 47.1 20.5 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RJW69722.1 - 8.2e-11 41.8 22.9 2.7e-09 36.8 22.9 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RJW69722.1 - 3.3e-10 40.1 21.8 1.2e-09 38.2 21.6 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RJW69722.1 - 0.01 15.6 13.1 0.017 14.9 13.1 1.5 1 1 0 1 1 1 0 Olfactory receptor Mito_carr PF00153.27 RJW69723.1 - 3.5e-12 46.1 0.2 2.6e-09 36.9 0.1 2.6 3 0 0 3 3 3 2 Mitochondrial carrier protein CDI PF02234.19 RJW69724.1 - 0.12 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor FliD_C PF07195.12 RJW69725.1 - 0.0045 16.5 0.4 0.0045 16.5 0.4 4.2 4 1 0 4 4 4 1 Flagellar hook-associated protein 2 C-terminus Baculo_PEP_C PF04513.12 RJW69725.1 - 0.0076 16.3 23.3 0.16 12.0 2.2 5.3 5 1 0 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 RJW69725.1 - 0.009 15.4 9.2 0.33 10.3 0.1 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4407) CdvA PF18822.1 RJW69725.1 - 0.076 12.8 32.7 0.032 14.1 11.2 6.0 5 2 1 6 6 6 0 CdvA-like coiled-coil domain DASH_Dad3 PF08656.10 RJW69725.1 - 0.17 12.0 19.6 8.3 6.6 0.0 6.1 5 2 0 5 5 5 0 DASH complex subunit Dad3 FAM184 PF15665.5 RJW69725.1 - 0.23 11.2 20.5 0.073 12.8 11.3 3.4 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B FUSC PF04632.12 RJW69725.1 - 0.6 8.6 8.3 0.2 10.2 0.8 2.4 2 1 0 2 2 2 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.22 RJW69725.1 - 0.7 10.2 23.1 0.12 12.7 0.6 4.6 5 1 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Muted PF14942.6 RJW69725.1 - 2 8.7 23.2 1.1 9.6 0.2 4.4 3 2 1 4 4 4 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.12 RJW69725.1 - 2.1 8.4 24.1 11 6.1 3.0 5.9 5 2 1 6 6 6 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 RJW69725.1 - 6.1 5.6 27.8 0.42 9.4 13.5 3.4 4 0 0 4 4 4 0 Spc7 kinetochore protein Phage_Mu_Gam PF07352.12 RJW69725.1 - 6.9 6.6 14.4 5.8 6.8 5.4 3.9 3 1 1 4 4 4 0 Bacteriophage Mu Gam like protein DUF4164 PF13747.6 RJW69725.1 - 8.5 6.7 29.9 0.51 10.6 1.4 5.8 5 2 2 7 7 7 0 Domain of unknown function (DUF4164) FbpA PF05833.11 RJW69725.1 - 8.8 5.0 17.3 6.9 5.3 12.7 2.6 2 1 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) Gp-FAR-1 PF05823.12 RJW69725.1 - 9 6.6 9.8 6 7.2 4.3 2.8 3 1 0 3 3 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Colicin_V PF02674.16 RJW69726.1 - 0.07 13.1 8.2 0.25 11.3 7.7 2.0 1 1 0 1 1 1 0 Colicin V production protein MARVEL PF01284.23 RJW69726.1 - 0.093 12.8 15.2 0.15 12.1 15.2 1.4 1 1 0 1 1 1 0 Membrane-associating domain Ycf70 PF17382.2 RJW69726.1 - 0.35 11.3 2.0 19 5.8 0.0 2.5 1 1 1 3 3 3 0 Uncharacterized Ycf70-like CPP1-like PF11833.8 RJW69726.1 - 0.6 9.7 3.1 0.53 9.9 1.9 1.5 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2070 PF09843.9 RJW69726.1 - 0.74 8.0 3.8 0.78 7.9 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_U4 PF03419.13 RJW69726.1 - 0.85 8.9 5.4 1.1 8.5 5.4 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Epimerase PF01370.21 RJW69727.1 - 9.3e-51 172.6 0.0 1.2e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RJW69727.1 - 1.4e-09 37.8 0.3 3.9e-09 36.4 0.3 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RJW69727.1 - 0.00024 20.3 0.0 0.00049 19.3 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RJW69727.1 - 0.23 10.6 2.3 0.79 8.8 2.3 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein PARP PF00644.20 RJW69729.1 - 1.2e-60 204.5 0.1 2.2e-60 203.6 0.0 1.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 RJW69729.1 - 1.7e-37 128.6 0.8 2.6e-37 127.9 0.8 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Sugar_tr PF00083.24 RJW69730.1 - 1.7e-24 86.5 22.8 2.4e-24 86.0 22.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW69730.1 - 2.6e-18 66.1 33.4 2.6e-18 66.1 33.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 RJW69733.1 - 1.1e-22 80.6 0.0 7.8e-11 41.7 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RJW69733.1 - 0.00058 19.0 1.7 0.17 10.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Rubredoxin_C PF18267.1 RJW69733.1 - 0.00094 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox PF00070.27 RJW69733.1 - 0.013 16.0 0.3 2 9.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RJW69733.1 - 0.027 14.7 0.7 0.095 12.9 0.6 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 RJW69733.1 - 0.09 12.8 0.2 3.9 7.4 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding SAM_2 PF07647.17 RJW69735.1 - 0.009 16.1 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SOAR PF16533.5 RJW69735.1 - 0.03 14.3 0.4 0.062 13.3 0.4 1.5 1 0 0 1 1 1 0 STIM1 Orai1-activating region Orai-1 PF07856.12 RJW69736.1 - 2.2e-36 125.1 10.8 2.8e-36 124.8 10.8 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity p53-inducible11 PF14936.6 RJW69736.1 - 0.98 9.4 9.2 0.093 12.8 3.8 1.8 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 ABC2_membrane_6 PF06182.11 RJW69736.1 - 3.2 7.5 16.0 0.58 9.9 7.2 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2374 PF09574.10 RJW69736.1 - 4.7 7.1 9.3 2.1 8.2 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (Duf2374) DUF4703 PF15775.5 RJW69738.1 - 0.69 9.7 5.4 1.4 8.7 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Cyclin PF08613.11 RJW69739.1 - 3e-08 34.2 0.0 6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin COesterase PF00135.28 RJW69740.1 - 1.1e-06 27.8 0.0 0.006 15.5 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family COesterase PF00135.28 RJW69743.1 - 6.2e-130 434.5 0.0 8.1e-130 434.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RJW69743.1 - 6e-06 26.3 0.4 4.6e-05 23.4 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pro_isomerase PF00160.21 RJW69744.1 - 2.4e-49 167.6 0.2 2.8e-49 167.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TLD PF07534.16 RJW69745.1 - 3.5e-07 30.5 0.0 5.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 TLD CPSase_L_D2 PF02786.17 RJW69747.1 - 1.3e-101 338.5 0.1 4.3e-77 258.4 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.21 RJW69747.1 - 6.1e-45 152.9 0.0 1.3e-44 151.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 RJW69747.1 - 2.1e-34 118.5 0.0 4.9e-34 117.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.28 RJW69747.1 - 9.5e-29 100.5 0.1 2e-28 99.5 0.1 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ATP-grasp PF02222.22 RJW69747.1 - 5.7e-14 52.1 0.1 9.6e-09 35.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 RJW69747.1 - 2.8e-13 49.9 0.1 2.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 RJW69747.1 - 1.2e-11 44.5 0.0 5.6e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 RJW69747.1 - 1.5e-11 44.3 0.0 3.5e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain Amidohydro_1 PF01979.20 RJW69747.1 - 8.5e-08 31.9 0.0 8e-06 25.4 0.1 2.3 2 0 0 2 2 2 1 Amidohydrolase family RimK PF08443.11 RJW69747.1 - 1.2e-05 25.0 0.1 0.0017 17.9 0.0 2.5 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 RJW69747.1 - 0.00021 21.4 0.2 0.026 14.5 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain Peptidase_C26 PF07722.13 RJW69747.1 - 0.0047 16.7 1.4 0.063 13.0 1.4 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_5 PF13549.6 RJW69747.1 - 0.0064 16.0 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 RJW69747.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OTCace PF00185.24 RJW69747.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DHOase PF12890.7 RJW69747.1 - 0.14 12.1 0.2 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Dihydro-orotase-like KcnmB2_inactiv PF09303.10 RJW69747.1 - 1.1 9.1 6.0 22 5.0 1.2 3.3 3 0 0 3 3 3 0 KCNMB2, ball and chain domain GON PF08685.11 RJW69748.1 - 2.7e-23 82.9 0.1 7.7e-22 78.2 0.1 2.8 1 1 0 1 1 1 1 GON domain TSP_1 PF00090.19 RJW69748.1 - 2.6e-15 56.3 81.1 0.00011 22.4 0.7 11.8 12 1 0 12 12 12 7 Thrombospondin type 1 domain Zn_ribbon_17 PF17120.5 RJW69748.1 - 0.059 13.0 0.1 0.059 13.0 0.1 6.7 6 0 0 6 6 6 0 Zinc-ribbon, C4HC2 type HGTP_anticodon PF03129.20 RJW69750.1 - 3.4e-18 65.6 0.0 1.7e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 RJW69750.1 - 4.9e-10 39.7 0.0 1.5e-09 38.1 0.0 2.0 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 RJW69750.1 - 8.6e-10 38.6 1.0 8.6e-10 38.6 1.0 1.9 2 0 0 2 2 2 1 WHEP-TRS domain Peptidase_C12 PF01088.21 RJW69751.1 - 5.6e-58 196.2 0.0 6.4e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_A17 PF05380.13 RJW69752.1 - 1.3e-22 80.5 0.1 2.5e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Pao retrotransposon peptidase Asp_protease_2 PF13650.6 RJW69752.1 - 3.8e-06 27.4 0.0 7.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF5641 PF18701.1 RJW69752.1 - 8.5e-06 25.8 1.6 8.5e-06 25.8 1.6 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5641) gag-asp_proteas PF13975.6 RJW69752.1 - 0.001 19.6 0.0 0.0021 18.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 RJW69752.1 - 0.0097 16.1 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.20 RJW69752.1 - 0.027 14.7 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.12 RJW69752.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RINGv PF12906.7 RJW69754.1 - 4.8e-12 45.8 13.6 8.8e-12 45.0 13.6 1.5 1 0 0 1 1 1 1 RING-variant domain zf-CSL PF05207.13 RJW69754.1 - 0.91 9.3 5.0 3.4 7.4 5.0 1.9 1 1 0 1 1 1 0 CSL zinc finger zf-RING_2 PF13639.6 RJW69754.1 - 1.4 9.3 9.0 3.1 8.2 9.0 1.6 1 0 0 1 1 1 0 Ring finger domain SNase PF00565.17 RJW69755.1 - 5.3e-54 181.3 0.0 1.8e-11 44.5 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 RJW69755.1 - 3.4e-16 59.4 0.0 6.3e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Tudor domain RIF5_SNase_2 PF18189.1 RJW69755.1 - 0.074 12.8 0.4 1.9 8.3 0.0 2.7 3 0 0 3 3 3 0 TbRIF5 SNase domain 2 Agenet PF05641.12 RJW69755.1 - 0.11 13.0 0.0 0.56 10.7 0.0 2.3 1 0 0 1 1 1 0 Agenet domain SMN PF06003.12 RJW69755.1 - 0.13 11.5 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RVT_1 PF00078.27 RJW69756.1 - 3.2e-10 39.9 0.0 4.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF PF00008.27 RJW69757.1 - 1.6e-41 140.2 119.6 1.3e-07 31.8 6.6 9.6 9 0 0 9 9 9 7 EGF-like domain LRR_8 PF13855.6 RJW69757.1 - 2.6e-39 132.8 34.2 3.8e-13 49.0 4.5 5.1 3 2 2 5 5 5 4 Leucine rich repeat hEGF PF12661.7 RJW69757.1 - 6.2e-23 80.6 95.5 9.5e-06 26.1 4.8 10.1 10 0 0 10 10 8 7 Human growth factor-like EGF Laminin_G_1 PF00054.23 RJW69757.1 - 1e-17 64.6 0.0 1.6e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 RJW69757.1 - 2.2e-16 60.6 0.0 3.9e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain LRR_5 PF13306.6 RJW69757.1 - 5.6e-16 58.7 10.2 5.2e-08 32.9 3.0 3.0 3 0 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 RJW69757.1 - 5.4e-15 55.3 39.8 0.0003 21.1 2.4 6.5 3 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW69757.1 - 5.8e-11 42.2 12.8 3.7e-05 23.3 0.3 3.9 2 2 2 4 4 4 4 Leucine-rich repeat EGF_2 PF07974.13 RJW69757.1 - 7e-09 35.9 140.1 0.00092 19.5 12.9 10.0 10 0 0 10 10 9 7 EGF-like domain LRRNT PF01462.18 RJW69757.1 - 4.5e-06 26.2 1.9 4.5e-06 26.2 1.9 5.0 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 RJW69757.1 - 0.016 15.6 32.7 1.6 9.6 0.5 9.6 9 0 0 9 9 8 0 Leucine Rich Repeat DUF4559 PF15112.6 RJW69757.1 - 0.021 14.5 1.1 0.033 13.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Pkinase PF00069.25 RJW69759.1 - 7e-21 74.8 0.0 6.5e-20 71.6 0.0 2.4 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69759.1 - 3.4e-14 52.8 0.0 7.9e-07 28.6 0.0 4.2 4 1 0 4 4 4 3 Protein tyrosine kinase Mob1_phocein PF03637.17 RJW69760.1 - 1.9e-35 122.3 1.5 2.6e-35 121.9 1.5 1.2 1 0 0 1 1 1 1 Mob1/phocein family zf-H2C2_2 PF13465.6 RJW69761.1 - 3.6e-10 39.8 27.4 7.5e-07 29.3 1.3 5.1 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 RJW69761.1 - 4.3e-08 33.2 34.5 0.00046 20.5 1.6 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW69761.1 - 4.3e-07 30.2 31.9 0.00023 21.7 1.4 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW69761.1 - 2.1e-06 27.9 23.4 0.0039 17.5 3.6 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW69761.1 - 0.01 16.2 24.0 0.011 16.1 1.7 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type PHD PF00628.29 RJW69761.1 - 0.13 12.2 10.9 0.77 9.7 3.0 3.0 2 1 0 2 2 2 0 PHD-finger zf-C2H2_9 PF16293.5 RJW69761.1 - 0.26 11.2 5.3 7.3 6.5 0.0 3.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 RJW69761.1 - 1.6 8.8 27.7 0.51 10.4 1.5 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Ta0938 PF11494.8 RJW69761.1 - 3 8.2 6.2 0.84 10.0 0.6 2.6 2 1 2 4 4 4 0 Ta0938 zinc-ribbons_6 PF07191.12 RJW69761.1 - 3.5 7.7 13.5 17 5.4 1.0 3.4 1 1 1 2 2 2 0 zinc-ribbons SprT-like PF10263.9 RJW69762.1 - 0.0025 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 SprT-like family RVT_1 PF00078.27 RJW69763.1 - 2.1e-22 79.8 0.1 2.7e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT PF03062.19 RJW69763.1 - 0.045 13.1 0.2 0.07 12.5 0.2 1.3 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family NAD_binding_10 PF13460.6 RJW69764.1 - 1.1e-05 25.5 0.1 1.5e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 RJW69764.1 - 0.00024 21.6 0.1 0.00047 20.6 0.1 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 RJW69764.1 - 0.0071 15.8 0.1 0.0093 15.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 RJW69764.1 - 0.0086 16.2 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 RJW69764.1 - 0.042 14.1 0.1 0.07 13.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MlaA PF04333.13 RJW69764.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 MlaA lipoprotein AdoMet_MTase PF07757.13 RJW69765.1 - 6.6e-41 139.2 0.1 1e-40 138.5 0.1 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 RJW69765.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 RJW69765.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 RJW69765.1 - 0.017 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 RJW69765.1 - 0.029 15.0 0.0 0.07 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 RJW69765.1 - 0.13 11.9 0.1 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 RJW69765.1 - 0.16 12.7 0.0 0.35 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 RJW69765.1 - 0.19 12.5 0.0 0.39 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LRR_8 PF13855.6 RJW69766.1 - 2.3e-71 235.5 58.8 1e-17 63.6 1.5 6.2 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 RJW69766.1 - 6.2e-27 93.2 35.1 1.1e-06 28.8 0.6 7.3 4 1 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RJW69766.1 - 7e-23 81.0 0.1 8e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RJW69766.1 - 9.7e-16 57.8 15.6 2.9e-06 26.9 1.5 4.1 2 2 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 RJW69766.1 - 7.8e-12 44.0 42.7 0.58 10.9 0.1 11.6 11 0 0 11 11 11 6 Leucine Rich Repeat LRRNT PF01462.18 RJW69766.1 - 2.8e-08 33.2 25.7 1.2e-05 24.8 5.3 4.0 4 2 1 5 5 5 2 Leucine rich repeat N-terminal domain LRR_2 PF07723.13 RJW69766.1 - 1.6e-05 25.3 0.9 6.7 7.5 0.0 6.2 6 0 0 6 6 6 1 Leucine Rich Repeat LRRCT PF01463.24 RJW69766.1 - 0.0036 17.7 0.4 0.025 15.1 0.4 2.6 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Reprolysin PF01421.19 RJW69767.1 - 2e-14 54.0 0.1 6e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 RJW69767.1 - 8.3e-14 52.2 0.0 1.3e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 ADAM_CR_2 PF17771.1 RJW69767.1 - 1.5e-10 41.4 1.2 4.3e-10 40.0 1.2 1.7 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 RJW69767.1 - 1.5e-08 35.2 0.0 2.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RJW69767.1 - 1.7e-07 31.3 0.0 3.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RJW69767.1 - 1.6e-06 27.9 0.0 2.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 RJW69767.1 - 0.1 12.2 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 RJW69767.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.13 RJW69767.1 - 0.2 11.5 0.2 0.4 10.6 0.2 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF1759 PF03564.15 RJW69768.1 - 0.0056 16.6 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF2236 PF09995.9 RJW69768.1 - 0.046 13.9 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) SCVP PF17619.2 RJW69768.1 - 0.047 14.5 0.0 0.094 13.6 0.0 1.4 1 0 0 1 1 1 0 Secreted clade V proteins SpoIISA_toxin PF14171.6 RJW69768.1 - 0.17 11.5 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Helicase_C PF00271.31 RJW69769.1 - 1.3e-21 77.0 0.1 4.6e-17 62.4 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 RJW69769.1 - 5.7e-15 55.5 0.0 1.6e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 RJW69769.1 - 1.6e-06 27.9 2.2 4.1e-06 26.6 2.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RJW69769.1 - 0.028 14.4 0.3 0.079 12.9 0.3 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 RJW69769.1 - 0.067 13.0 2.2 0.18 11.7 2.2 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 RJW69769.1 - 0.086 12.6 1.8 0.27 11.0 1.8 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PGK PF00162.19 RJW69770.1 - 1.9e-153 510.9 0.3 2.1e-153 510.8 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Peptidase_S51 PF03575.17 RJW69770.1 - 0.12 12.0 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S51 BAR_3_WASP_bdg PF10456.9 RJW69771.1 - 3.8e-27 95.3 0.0 6.2e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 RJW69771.1 - 1.3e-25 89.6 0.5 4.5e-25 87.8 0.2 2.2 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.6 RJW69771.1 - 3.5e-10 39.6 0.1 1.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 RJW69771.1 - 1.9e-09 37.0 0.0 4.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RJW69771.1 - 1.1e-06 28.2 0.0 2.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PI-PLC-X PF00388.19 RJW69771.1 - 0.087 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Gas_vesicle_C PF01304.17 RJW69771.1 - 0.092 12.8 0.0 0.46 10.5 0.0 2.3 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Lamp PF01299.17 RJW69774.1 - 0.00028 20.7 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Adeno_E3_CR2 PF02439.15 RJW69774.1 - 0.0082 15.9 0.5 0.012 15.3 0.5 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 RCR PF12273.8 RJW69774.1 - 0.17 12.5 1.2 0.3 11.7 1.2 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red GST_C_3 PF14497.6 RJW69777.1 - 1e-12 48.1 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RJW69777.1 - 2.2e-08 34.3 0.0 1.2e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RJW69777.1 - 4.6e-07 30.0 0.0 7.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RJW69777.1 - 0.00095 19.5 0.0 0.0051 17.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RJW69777.1 - 0.018 15.0 0.0 0.042 13.9 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain zf-MYND PF01753.18 RJW69780.1 - 0.0061 16.6 14.1 0.0061 16.6 14.1 3.1 3 0 0 3 3 3 1 MYND finger DUF2465 PF10239.9 RJW69781.1 - 1.9e-76 257.4 0.0 2.7e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) RVT_1 PF00078.27 RJW69781.1 - 6.5e-15 55.3 0.0 3.2e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SURF1 PF02104.15 RJW69785.1 - 5.6e-35 121.2 0.0 7e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 SURF1 family DUF3756 PF12581.8 RJW69785.1 - 0.042 13.7 0.6 6.1 6.8 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) TPR_11 PF13414.6 RJW69786.1 - 1.6e-16 59.7 4.7 7.2e-10 38.4 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 RJW69786.1 - 1.5e-15 56.2 0.4 0.00015 21.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW69786.1 - 9.5e-10 37.9 0.7 0.11 12.6 0.0 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RJW69786.1 - 1.8e-09 37.3 1.2 0.01 16.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RJW69786.1 - 2.7e-09 37.1 1.9 1.3e-07 31.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW69786.1 - 7e-07 29.8 6.4 0.0005 20.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW69786.1 - 8.2e-07 29.3 5.8 0.0028 18.3 0.1 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW69786.1 - 8.8e-07 28.7 0.8 0.013 15.7 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW69786.1 - 4.4e-05 23.7 4.1 0.0044 17.3 1.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW69786.1 - 5.8e-05 23.5 4.4 0.24 11.9 0.1 3.2 2 1 2 4 4 3 3 Tetratricopeptide repeat S1 PF00575.23 RJW69786.1 - 0.00094 19.5 0.0 0.0033 17.7 0.0 1.8 2 0 0 2 2 2 1 S1 RNA binding domain NARP1 PF12569.8 RJW69786.1 - 0.065 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 HCNGP PF07818.13 RJW69786.1 - 0.067 13.9 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 HCNGP-like protein TPR_7 PF13176.6 RJW69786.1 - 0.11 12.5 0.1 4.9 7.4 0.0 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 RJW69786.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 SHNi-TPR TPR_20 PF14561.6 RJW69786.1 - 0.68 10.3 0.0 0.68 10.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NDUF_B5 PF09781.9 RJW69787.1 - 5.6e-44 150.0 0.0 8e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Amidinotransf PF02274.17 RJW69788.1 - 8.5e-06 25.1 0.2 0.0012 18.0 0.0 2.2 1 1 1 2 2 2 2 Amidinotransferase TMP-TENI PF02581.17 RJW69788.1 - 0.062 12.6 0.1 0.12 11.7 0.1 1.6 1 1 0 1 1 1 0 Thiamine monophosphate synthase GST_C_3 PF14497.6 RJW69789.1 - 2.1e-15 56.7 0.1 3.7e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RJW69789.1 - 8.9e-09 35.5 0.0 2.8e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RJW69789.1 - 0.00062 19.7 0.0 0.001 19.0 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RJW69789.1 - 0.0023 18.2 0.0 0.014 15.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain TGS PF02824.21 RJW69790.1 - 1.2e-05 25.3 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 TGS domain Pkinase PF00069.25 RJW69791.1 - 2.7e-67 226.9 0.0 3.5e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69791.1 - 3.4e-38 131.4 0.0 4.8e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW69791.1 - 0.004 16.1 0.2 0.0056 15.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RJW69791.1 - 0.021 14.1 0.0 0.088 12.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 RJW69791.1 - 0.06 12.1 0.0 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase RhoGEF PF00621.20 RJW69793.1 - 4.8e-25 88.9 1.0 1e-24 87.8 1.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Gryzun-like PF12742.7 RJW69795.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking KH_1 PF00013.29 RJW69796.1 - 1.9e-08 34.0 0.0 3.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 KH domain Endostatin PF06482.11 RJW69796.1 - 7.7 5.9 12.5 11 5.4 12.5 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin zf-C2H2 PF00096.26 RJW69798.1 - 1.1e-10 41.4 27.1 5.9e-06 26.5 3.1 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW69798.1 - 3.1e-09 36.8 20.9 6.2e-07 29.6 1.7 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW69798.1 - 5.1e-08 33.1 26.6 0.0024 18.6 2.4 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RJW69798.1 - 2.8e-05 23.8 1.7 2.8e-05 23.8 1.7 4.3 6 0 0 6 6 5 1 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.6 RJW69798.1 - 0.02 15.0 0.5 0.052 13.6 0.5 1.7 1 0 0 1 1 1 0 Zinc-finger zf-C2H2_jaz PF12171.8 RJW69798.1 - 0.38 11.1 19.0 0.72 10.2 0.4 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 RJW69798.1 - 1.3 8.9 5.9 0.98 9.3 0.2 2.5 2 0 0 2 2 2 0 U1 zinc finger HNH PF01844.23 RJW69798.1 - 3.2 8.0 7.7 54 4.1 0.1 3.5 3 0 0 3 3 3 0 HNH endonuclease zf-C2H2_2 PF12756.7 RJW69798.1 - 3.2 8.1 16.2 10 6.5 0.9 4.3 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 RJW69798.1 - 3.6 7.8 20.6 0.18 12.0 5.6 2.9 3 0 0 3 3 2 0 FYVE zinc finger PyrI_C PF02748.15 RJW69798.1 - 3.9 7.4 8.8 11 6.0 0.6 3.5 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF3268 PF11672.8 RJW69798.1 - 6.9 7.0 9.7 0.74 10.2 4.5 2.0 1 1 0 2 2 2 0 zinc-finger-containing domain Lamp PF01299.17 RJW69799.1 - 9.5e-08 32.0 1.3 1.6e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Lysosome-associated membrane glycoprotein (Lamp) Peptidase_M30 PF10460.9 RJW69799.1 - 0.07 12.1 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase M30 NPDC1 PF06809.11 RJW69803.1 - 2.3e-23 82.8 0.0 5.3e-23 81.6 0.0 1.5 2 0 0 2 2 2 1 Neural proliferation differentiation control-1 protein (NPDC1) Histone PF00125.24 RJW69804.1 - 1.1e-38 132.6 0.2 1.3e-38 132.3 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Imm-NTF2 PF15655.6 RJW69804.1 - 0.0013 19.0 0.0 0.046 14.0 0.0 2.1 2 0 0 2 2 2 1 NTF2 fold immunity protein CENP-T_C PF15511.6 RJW69804.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RJW69804.1 - 0.038 14.4 0.0 0.063 13.7 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein Amnionless PF14828.6 RJW69805.1 - 0.15 10.8 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 Amnionless Colicin_V PF02674.16 RJW69808.1 - 0.66 9.9 47.0 1.8e+04 -19.0 47.0 5.0 1 1 0 1 1 1 0 Colicin V production protein GtrA PF04138.14 RJW69808.1 - 1.8 8.8 60.3 1.8e+04 -20.6 60.3 4.9 1 1 0 1 1 1 0 GtrA-like protein Pellino PF04710.14 RJW69810.1 - 4.8e-100 335.1 0.0 9.2e-100 334.2 0.0 1.4 1 1 0 1 1 1 1 Pellino Exo_endo_phos_2 PF14529.6 RJW69812.1 - 4.2e-05 23.4 0.0 6.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW69812.1 - 0.045 13.3 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF2656 PF10847.8 RJW69812.1 - 0.059 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) MT-A70 PF05063.14 RJW69814.1 - 9.9e-55 185.1 0.0 1.6e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 MT-A70 DUF4498 PF14926.6 RJW69814.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) RVT_1 PF00078.27 RJW69815.1 - 0.00034 20.2 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WGG PF10273.9 RJW69816.1 - 1.8e-12 47.7 0.0 3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RP853 PF17542.2 RJW69816.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 DSPc PF00782.20 RJW69817.1 - 2.8e-18 66.0 0.1 3.7e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain dCache_1 PF02743.18 RJW69817.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Cache domain DUF3535 PF12054.8 RJW69817.1 - 0.15 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) AAA_23 PF13476.6 RJW69818.1 - 0.1 13.1 7.4 0.11 12.9 7.4 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 RJW69818.1 - 2.1 7.9 8.7 2.2 7.8 8.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 RJW69818.1 - 2.7 6.7 3.9 2.7 6.7 3.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 RJW69818.1 - 3.1 7.5 12.4 3.2 7.5 12.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GPP34 PF05719.11 RJW69819.1 - 7.4e-53 179.6 0.1 9.6e-53 179.2 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SSF PF00474.17 RJW69821.1 - 4.8e-103 345.2 8.5 6.5e-103 344.7 8.5 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family mRNA_cap_enzyme PF01331.19 RJW69822.1 - 5.9e-43 147.0 0.0 4.2e-42 144.2 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DSPc PF00782.20 RJW69822.1 - 4.2e-13 49.3 0.0 7.2e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain mRNA_cap_C PF03919.15 RJW69822.1 - 6.2e-10 39.7 0.0 1.4e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Y_phosphatase PF00102.27 RJW69822.1 - 0.00096 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DNA_ligase_A_M PF01068.21 RJW69822.1 - 0.0017 18.1 0.0 0.0053 16.4 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain PTPlike_phytase PF14566.6 RJW69822.1 - 0.0038 17.3 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 RJW69822.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RJW69822.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1211 PF06736.11 RJW69822.1 - 0.8 10.2 4.1 0.97 9.9 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) DEAD PF00270.29 RJW69824.1 - 5.3e-07 29.6 0.1 1.3e-06 28.3 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 RJW69824.1 - 2.6e-05 24.8 0.1 5.4e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif AAA_19 PF13245.6 RJW69824.1 - 0.00015 22.1 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW69824.1 - 0.00059 20.1 0.3 0.0027 18.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 RJW69824.1 - 0.0043 16.4 0.0 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_11 PF13086.6 RJW69824.1 - 0.0094 15.8 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RJW69824.1 - 0.032 14.2 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 RJW69824.1 - 0.085 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RJW69824.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Na_H_Exchanger PF00999.21 RJW69826.1 - 1.7e-72 244.4 31.5 4.9e-72 242.8 31.5 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family LapA_dom PF06305.11 RJW69826.1 - 0.0023 17.7 1.2 0.45 10.4 0.1 3.1 3 0 0 3 3 3 2 Lipopolysaccharide assembly protein A domain Ank_2 PF12796.7 RJW69827.1 - 6.9e-12 45.8 0.3 2.2e-11 44.2 0.2 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RJW69827.1 - 3.2e-11 43.2 4.0 0.026 15.0 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RJW69827.1 - 1.5e-10 41.4 3.1 6.9e-06 26.5 0.8 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW69827.1 - 2.2e-05 24.5 1.0 11 7.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RJW69827.1 - 0.00085 19.6 2.9 0.0022 18.2 1.1 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Synthase_beta PF11421.8 RJW69828.1 - 0.44 11.3 4.2 0.23 12.2 1.5 2.0 2 1 0 2 2 2 0 ATP synthase F1 beta subunit DUF1676 PF07898.13 RJW69829.1 - 0.076 13.0 11.4 0.1 12.7 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Ac81 PF05820.11 RJW69829.1 - 0.21 11.1 4.8 0.22 11.1 4.8 1.0 1 0 0 1 1 1 0 Baculoviridae AC81 Pkinase PF00069.25 RJW69834.1 - 1.7e-11 44.0 0.0 3.7e-09 36.3 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69834.1 - 0.00021 20.6 0.0 0.034 13.4 0.0 3.6 4 1 0 4 4 4 1 Protein tyrosine kinase APH PF01636.23 RJW69834.1 - 0.058 13.3 0.0 0.41 10.5 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family C2 PF00168.30 RJW69836.1 - 3.8e-56 187.7 0.0 4.4e-29 100.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 RJW69836.1 - 1.2e-05 24.9 0.0 0.22 11.1 0.0 2.6 2 0 0 2 2 2 2 CEP76 C2 domain Syndecan PF01034.20 RJW69836.1 - 0.015 15.2 2.0 0.034 14.1 2.0 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 RJW69836.1 - 0.047 13.6 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DOCK-C2 PF14429.6 RJW69836.1 - 0.061 13.1 0.1 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins EphA2_TM PF14575.6 RJW69836.1 - 0.16 12.9 0.0 0.33 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ABC1 PF03109.16 RJW69838.1 - 2.9e-60 201.6 0.0 7.9e-34 116.4 0.0 2.8 2 0 0 2 2 2 2 ABC1 family RVT_1 PF00078.27 RJW69838.1 - 4.5e-46 157.2 0.3 1e-45 155.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW69838.1 - 1.6e-11 44.0 0.0 7.7e-11 41.9 0.0 2.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase AAA_5 PF07728.14 RJW69838.1 - 0.061 13.3 0.0 8.9 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IDO PF01231.18 RJW69841.1 - 1.1e-18 67.3 0.0 1.2e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PDZ PF00595.24 RJW69842.1 - 7.4e-24 83.9 0.1 1.3e-08 35.1 0.1 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 RJW69842.1 - 5.6e-18 64.5 0.4 0.00029 20.6 0.1 3.8 3 0 0 3 3 3 3 PDZ domain Kelch_3 PF13415.6 RJW69842.1 - 5.4e-17 61.6 6.9 3.6e-07 30.3 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 RJW69842.1 - 8.4e-14 51.3 14.7 3e-05 24.0 0.1 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 RJW69842.1 - 2.6e-10 39.7 0.9 4.4e-05 23.0 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Asp PF00026.23 RJW69842.1 - 1.1e-09 38.2 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease F-box-like PF12937.7 RJW69842.1 - 5.7e-09 35.7 0.9 2.6e-08 33.6 0.9 2.2 1 0 0 1 1 1 1 F-box-like Kelch_6 PF13964.6 RJW69842.1 - 2.4e-07 30.8 6.5 0.00023 21.3 0.0 5.3 4 1 0 4 4 4 1 Kelch motif PDZ_2 PF13180.6 RJW69842.1 - 4.3e-07 30.2 0.1 0.005 17.1 0.0 3.3 3 0 0 3 3 3 2 PDZ domain Kelch_5 PF13854.6 RJW69842.1 - 2e-06 27.6 8.1 0.13 12.3 0.0 4.9 6 0 0 6 6 5 3 Kelch motif F-box PF00646.33 RJW69842.1 - 7e-06 25.8 0.6 2e-05 24.3 0.6 1.8 1 0 0 1 1 1 1 F-box domain Kelch_2 PF07646.15 RJW69842.1 - 0.0044 16.9 12.8 0.022 14.7 0.1 4.6 4 0 0 4 4 3 2 Kelch motif F-box_4 PF15966.5 RJW69842.1 - 0.0045 16.9 0.5 0.013 15.4 0.1 2.0 2 0 0 2 2 2 1 F-box zf-CCCH_2 PF14608.6 RJW69842.1 - 4.1 8.0 8.0 2 9.0 0.4 3.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Pyridoxal_deC PF00282.19 RJW69843.1 - 2.4e-23 82.5 0.0 3.5e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 RJW69843.1 - 5.7e-09 35.4 0.0 1.7e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RJW69843.1 - 0.00013 21.4 0.2 0.00023 20.6 0.2 1.3 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_7N PF13733.6 RJW69845.1 - 6.1e-38 129.5 0.1 1.1e-37 128.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RJW69845.1 - 2.8e-23 81.3 0.1 6.1e-23 80.3 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase ToxB_N PF18224.1 RJW69848.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 ToxB N-terminal domain RasGEF PF00617.19 RJW69849.1 - 1.1e-31 110.4 1.1 2.2e-31 109.5 1.1 1.5 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.29 RJW69849.1 - 2.7e-11 43.4 0.0 1.3e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain RasGEF_N PF00618.20 RJW69849.1 - 0.00036 20.7 0.6 0.0035 17.6 0.1 2.8 2 1 0 2 2 2 1 RasGEF N-terminal motif Zip PF02535.22 RJW69851.1 - 0.057 12.6 2.4 0.064 12.5 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mt_ATP-synt_B PF05405.14 RJW69852.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RRM_1 PF00076.22 RJW69855.1 - 9.7e-46 153.5 0.0 4.8e-18 64.8 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW69855.1 - 3.3e-05 23.5 0.4 0.89 9.2 0.1 3.6 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RJW69855.1 - 0.016 15.0 0.0 9.3 6.2 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_7 PF16367.5 RJW69855.1 - 0.029 14.5 0.0 7.7 6.7 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif Ran_BP1 PF00638.18 RJW69856.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 RanBP1 domain SAC3_GANP PF03399.16 RJW69857.1 - 1.5e-06 27.8 2.3 4.8e-06 26.2 0.5 2.3 2 1 0 2 2 2 1 SAC3/GANP family DUF4778 PF16008.5 RJW69859.1 - 2 8.4 3.7 3 7.8 3.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4778) IDO PF01231.18 RJW69860.1 - 4.7e-75 253.0 0.0 6.3e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase IDO PF01231.18 RJW69862.1 - 5e-34 117.8 0.1 7.2e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PDZ PF00595.24 RJW69863.1 - 2.8e-21 75.6 0.0 2.6e-06 27.7 0.1 5.1 5 0 0 5 5 5 3 PDZ domain PDZ_6 PF17820.1 RJW69863.1 - 3.6e-14 52.3 0.2 0.003 17.4 0.0 4.6 5 0 0 5 5 5 3 PDZ domain PDZ_2 PF13180.6 RJW69863.1 - 7.1e-09 35.9 0.0 0.017 15.4 0.0 3.9 4 0 0 4 4 4 3 PDZ domain PI3K_P85_iSH2 PF16454.5 RJW69864.1 - 0.08 12.5 32.0 0.23 11.0 1.7 4.4 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fib_alpha PF08702.10 RJW69864.1 - 0.17 12.1 41.8 0.072 13.3 3.9 5.0 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 RJW69864.1 - 0.18 11.7 29.9 3.3 7.7 2.7 6.9 7 0 0 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lebercilin PF15619.6 RJW69864.1 - 2.2 7.9 47.8 0.68 9.6 19.8 5.0 4 1 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Viral_P18 PF04521.13 RJW69864.1 - 2.3 8.0 5.5 1.4 8.8 1.5 2.7 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein MAD PF05557.13 RJW69864.1 - 4 5.7 42.8 0.036 12.4 5.5 3.5 2 1 0 3 3 3 0 Mitotic checkpoint protein TMF_TATA_bd PF12325.8 RJW69864.1 - 6.3 7.1 43.0 1.7 8.9 7.4 5.7 5 1 1 6 6 6 0 TATA element modulatory factor 1 TATA binding DUF5531 PF17671.1 RJW69865.1 - 0.094 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5531) Fer4_NifH PF00142.18 RJW69868.1 - 0.2 11.0 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Gal_Lectin PF02140.18 RJW69868.1 - 0.7 10.4 20.3 0.055 13.9 1.4 3.9 4 0 0 4 4 4 0 Galactose binding lectin domain eIF3_N PF09440.10 RJW69869.1 - 6.9e-32 110.7 1.6 1.8e-31 109.4 1.6 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain RPN7 PF10602.9 RJW69869.1 - 1.7e-05 24.6 0.0 3.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN7 SecA_SW PF07516.13 RJW69869.1 - 0.075 13.1 0.8 0.48 10.4 0.1 2.1 2 0 0 2 2 2 0 SecA Wing and Scaffold domain EF-hand_7 PF13499.6 RJW69872.1 - 1.6e-24 86.2 6.7 2.7e-16 59.8 0.3 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RJW69872.1 - 2.8e-24 82.8 6.7 2.3e-07 29.9 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RJW69872.1 - 1.7e-20 71.1 3.9 4.5e-05 23.0 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RJW69872.1 - 7.6e-19 66.3 2.7 0.00013 21.3 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RJW69872.1 - 3.7e-15 55.5 4.9 0.0003 20.6 0.1 3.8 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW69872.1 - 2.1e-05 24.8 1.0 0.023 15.0 0.6 3.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW69872.1 - 7.2e-05 22.7 1.4 0.066 13.2 0.1 3.3 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RJW69872.1 - 0.067 13.4 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 RJW69872.1 - 0.2 11.6 3.1 10 6.0 0.1 3.5 4 0 0 4 4 4 0 Caleosin related protein Aa_trans PF01490.18 RJW69873.1 - 3.5e-23 82.0 32.5 3.5e-23 82.0 32.5 2.3 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Pkinase PF00069.25 RJW69876.1 - 7.1e-68 228.8 0.0 8.5e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69876.1 - 3.7e-33 114.9 0.0 4.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW69876.1 - 0.038 13.3 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RVT_1 PF00078.27 RJW69877.1 - 0.0035 16.9 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANAPC4_WD40 PF12894.7 RJW69878.1 - 0.02 15.2 0.0 1.9 8.8 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW69878.1 - 0.35 11.8 5.5 9.8 7.2 0.4 4.7 6 0 0 6 6 6 0 WD domain, G-beta repeat Guanylate_cyc PF00211.20 RJW69879.1 - 5.8e-66 221.6 0.0 8.9e-66 221.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 RJW69879.1 - 1.3e-28 100.1 0.0 1.9e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW69879.1 - 2e-22 79.8 0.0 2.9e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 RJW69879.1 - 6.5e-06 25.7 0.6 1.1e-05 25.1 0.6 1.3 1 0 0 1 1 1 1 Heme NO binding associated Noggin PF05806.12 RJW69880.1 - 5.8e-31 108.1 7.6 5.8e-31 108.1 7.6 2.3 2 1 0 2 2 2 1 Noggin HMG_CoA_synt_C PF08540.10 RJW69880.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal PRP3 PF08572.10 RJW69881.1 - 3.1e-78 262.6 5.2 3.1e-78 262.6 5.2 2.2 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 RJW69881.1 - 7.3e-41 139.7 1.8 8.2e-41 139.5 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) eIF_4EBP PF05456.11 RJW69881.1 - 0.027 14.4 0.8 0.073 13.0 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PWWP PF00855.17 RJW69882.1 - 6.4e-12 45.7 0.0 2.7e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 PWWP domain zf-CW PF07496.15 RJW69882.1 - 1.7e-06 27.9 3.3 4.7e-06 26.5 3.3 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger DUF4852 PF16144.5 RJW69882.1 - 0.02 15.0 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) AT_hook PF02178.19 RJW69882.1 - 0.12 12.3 4.9 0.27 11.2 4.9 1.7 1 0 0 1 1 1 0 AT hook motif Cnd1 PF12717.7 RJW69883.1 - 4.8e-45 153.5 7.5 5.4e-44 150.1 0.1 4.7 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 RJW69883.1 - 7.8e-27 94.2 0.0 7.8e-27 94.2 0.0 2.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 RJW69883.1 - 5.7e-06 26.1 13.0 0.57 10.6 0.0 8.2 9 0 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.20 RJW69883.1 - 2.6e-05 23.0 1.3 0.00027 19.6 0.4 3.0 2 1 0 3 3 3 1 Adaptin N terminal region HEAT_2 PF13646.6 RJW69883.1 - 0.00016 22.0 0.7 0.043 14.2 0.0 5.1 4 2 1 5 5 5 1 HEAT repeats MMS22L_C PF14911.6 RJW69883.1 - 0.0094 15.1 2.2 0.033 13.3 0.0 3.0 4 0 0 4 4 4 1 S-phase genomic integrity recombination mediator, C-terminal RTP1_C1 PF10363.9 RJW69883.1 - 0.017 15.3 0.1 3.9 7.7 0.0 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 RJW69883.1 - 0.033 13.4 0.2 0.033 13.4 0.2 3.0 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 RJW69883.1 - 0.32 11.5 4.0 2.6 8.7 0.1 4.5 4 1 1 5 5 5 0 HEAT-like repeat DUF755 PF05501.11 RJW69883.1 - 0.69 10.2 15.2 0.46 10.8 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF755) 7tm_1 PF00001.21 RJW69885.1 - 8.4e-10 38.4 15.7 1.4e-09 37.7 15.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRT_C PF08372.10 RJW69885.1 - 0.13 12.0 0.8 0.4 10.4 0.1 2.2 2 1 1 3 3 3 0 Plant phosphoribosyltransferase C-terminal SPC12 PF06645.13 RJW69885.1 - 3.3 7.8 9.0 5.3 7.2 0.1 3.8 3 1 1 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) PWWP PF00855.17 RJW69886.1 - 1.4e-10 41.4 0.1 6.1e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 PWWP domain zf-CW PF07496.15 RJW69886.1 - 3.4e-07 30.2 2.6 3.4e-07 30.2 2.6 2.6 3 0 0 3 3 3 1 CW-type Zinc Finger Rap_GAP PF02145.15 RJW69887.1 - 1.2e-60 204.2 0.1 2e-60 203.5 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP CNH PF00780.22 RJW69887.1 - 4e-34 118.5 1.1 2.2e-22 80.0 0.4 2.3 2 0 0 2 2 2 2 CNH domain GLTP PF08718.11 RJW69890.1 - 1.3e-34 119.6 0.0 2.7e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) CD20 PF04103.15 RJW69893.1 - 0.0007 19.7 23.4 0.0007 19.7 23.4 2.8 2 1 1 3 3 3 1 CD20-like family DUF1129 PF06570.11 RJW69893.1 - 0.26 10.8 1.4 7.1 6.1 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) CH PF00307.31 RJW69894.1 - 7.1e-12 45.5 0.5 8.2e-11 42.1 0.0 3.4 3 0 0 3 3 3 1 Calponin homology (CH) domain Spectrin PF00435.21 RJW69894.1 - 6.1e-06 26.7 1.6 6.1e-06 26.7 1.6 17.6 14 5 4 19 19 19 4 Spectrin repeat DUF2576 PF10845.8 RJW69894.1 - 0.033 13.8 0.5 0.1 12.2 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) DUF1722 PF08349.11 RJW69894.1 - 0.17 12.2 3.7 2.5 8.4 0.0 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1722) RNA_lig_T4_1 PF09511.10 RJW69894.1 - 0.51 10.2 3.5 1.6 8.6 1.5 2.8 2 0 0 2 2 2 0 RNA ligase MitMem_reg PF13012.6 RJW69894.1 - 1.4 9.3 16.7 0.35 11.3 0.4 6.5 4 3 1 5 5 5 0 Maintenance of mitochondrial structure and function Myb_CC_LHEQLE PF14379.6 RJW69894.1 - 1.8 8.3 5.8 2.3 8.0 0.0 3.9 4 0 0 4 4 4 0 MYB-CC type transfactor, LHEQLE motif AC_N PF16214.5 RJW69895.1 - 1.1 8.3 5.1 2.9 6.9 5.1 1.7 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region MORN PF02493.20 RJW69896.1 - 6.4e-28 95.0 39.9 4.4e-05 23.1 2.3 8.3 8 0 0 8 8 8 7 MORN repeat RIBIOP_C PF04950.12 RJW69897.1 - 1e-83 281.2 0.0 1.4e-64 218.3 0.0 2.2 2 0 0 2 2 2 2 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 RJW69897.1 - 0.065 13.3 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 AARP2CN (NUC121) domain RNA_pol_Rpb1_5 PF04998.17 RJW69898.1 - 5.9e-85 284.9 0.0 9.1e-85 284.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 RJW69898.1 - 6.7e-61 205.3 0.0 3.4e-60 203.0 0.0 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 RJW69898.1 - 3.6e-56 190.8 0.0 5.4e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 RJW69898.1 - 7.4e-39 133.2 0.0 1.8e-38 131.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 RJW69898.1 - 4.3e-30 103.8 0.0 9.8e-30 102.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 YidD PF01809.18 RJW69898.1 - 2 8.4 6.7 1 9.3 0.9 2.7 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor SNCAIP_SNCA_bd PF16700.5 RJW69899.1 - 0.64 9.8 2.2 22 4.9 0.2 2.2 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain TFIIE_alpha PF02002.17 RJW69900.1 - 5.2e-19 68.1 4.4 8.3e-19 67.4 4.4 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 RJW69900.1 - 6.8e-08 32.7 0.0 2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha HTH_Mga PF08280.11 RJW69900.1 - 0.078 13.0 0.5 0.2 11.7 0.5 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF4026 PF13218.6 RJW69900.1 - 0.1 11.6 0.3 0.16 10.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) Pox_MCEL PF03291.16 RJW69901.1 - 3.8e-63 213.6 0.0 4.8e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 RJW69901.1 - 5.9e-13 49.3 0.0 1.4e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW69901.1 - 1e-10 41.6 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RJW69901.1 - 2.8e-08 34.3 0.1 6.4e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RJW69901.1 - 1.5e-05 24.9 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RJW69901.1 - 2.5e-05 24.9 0.0 7.6e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 RJW69901.1 - 0.0062 15.8 0.0 0.0091 15.2 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.14 RJW69901.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain LLGL PF08366.13 RJW69903.1 - 6.5e-18 65.0 0.0 6.4e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 LLGL2 zf-C4 PF00105.18 RJW69905.1 - 9.8e-28 96.4 13.3 2.8e-27 95.0 13.3 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-MYND PF01753.18 RJW69908.1 - 1.4e-09 37.9 18.3 3.6e-09 36.6 18.3 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 RJW69908.1 - 0.27 11.1 7.9 0.63 10.0 7.9 1.7 1 0 0 1 1 1 0 HIT zinc finger PDEase_I PF00233.19 RJW69909.1 - 2.5e-68 230.4 2.7 8.3e-67 225.4 1.2 3.0 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RJW69909.1 - 1.6e-22 80.6 0.0 1.2e-13 51.9 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 RJW69909.1 - 1.9e-21 76.8 0.0 6.8e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 RJW69909.1 - 9.9e-11 42.1 0.0 0.00042 20.7 0.0 2.8 2 1 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 RJW69909.1 - 0.001 19.1 1.3 0.5 10.4 0.0 3.5 2 1 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor H_kinase_N PF12282.8 RJW69909.1 - 0.041 13.8 0.2 2.2 8.2 0.0 2.8 2 1 0 2 2 2 0 Signal transduction histidine kinase Rhomboid PF01694.22 RJW69910.1 - 2.2e-16 60.2 1.1 2.2e-16 60.2 1.1 1.6 2 0 0 2 2 2 1 Rhomboid family Carn_acyltransf PF00755.20 RJW69911.1 - 2.6e-187 624.0 0.0 3.2e-187 623.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA PF00004.29 RJW69912.1 - 1.5e-34 119.3 0.0 2.5e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW69912.1 - 8.2e-10 38.3 0.1 1.5e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RJW69912.1 - 1.3e-05 25.4 0.1 0.0016 18.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 RJW69912.1 - 3.5e-05 24.2 0.1 0.0003 21.2 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 RJW69912.1 - 4.6e-05 23.4 0.1 0.00028 20.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 RJW69912.1 - 0.00038 20.0 0.0 0.0011 18.5 0.0 1.8 2 0 0 2 2 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 RJW69912.1 - 0.0004 20.1 0.0 0.0011 18.7 0.0 1.7 1 1 1 2 2 2 1 IstB-like ATP binding protein TniB PF05621.11 RJW69912.1 - 0.00054 19.4 0.0 0.74 9.2 0.0 2.7 2 1 1 3 3 2 2 Bacterial TniB protein AAA_33 PF13671.6 RJW69912.1 - 0.00086 19.5 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RJW69912.1 - 0.0013 18.1 0.2 0.0043 16.5 0.2 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 RJW69912.1 - 0.002 17.9 0.0 0.0089 15.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 RJW69912.1 - 0.0038 17.3 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RJW69912.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 RJW69912.1 - 0.005 16.0 0.0 0.0078 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 RJW69912.1 - 0.01 16.4 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RJW69912.1 - 0.011 16.1 0.0 0.029 14.8 0.0 1.8 2 0 0 2 2 1 0 RNA helicase NACHT PF05729.12 RJW69912.1 - 0.012 15.5 0.1 0.045 13.7 0.0 1.9 1 1 1 2 2 2 0 NACHT domain AAA_2 PF07724.14 RJW69912.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 RJW69912.1 - 0.016 14.8 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 RJW69912.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 RJW69912.1 - 0.031 14.8 0.0 0.069 13.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.16 RJW69912.1 - 0.037 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 RJW69912.1 - 0.042 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 RJW69912.1 - 0.047 12.8 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 RJW69912.1 - 0.05 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 RJW69912.1 - 0.077 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RJW69912.1 - 0.08 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 RJW69912.1 - 0.09 12.7 0.0 0.79 9.6 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 RJW69912.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.13 RJW69912.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain PduV-EutP PF10662.9 RJW69912.1 - 0.15 11.8 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 RJW69912.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Forkhead PF00250.18 RJW69913.1 - 4e-34 116.7 0.3 8.9e-34 115.6 0.0 1.8 2 0 0 2 2 2 1 Forkhead domain Pkinase PF00069.25 RJW69914.1 - 2.9e-36 125.2 0.0 4.9e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69914.1 - 1.1e-21 77.3 0.0 1.9e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PTEN_C2 PF10409.9 RJW69914.1 - 1.7e-17 63.5 0.0 2.8e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Kinase-like PF14531.6 RJW69914.1 - 5.8e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RJW69914.1 - 0.00052 19.4 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DSPc PF00782.20 RJW69914.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Haspin_kinase PF12330.8 RJW69914.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Homeodomain PF00046.29 RJW69915.1 - 3.7e-29 100.3 3.2 7.7e-15 54.5 0.1 2.9 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 RJW69915.1 - 2.3e-05 24.2 0.0 0.12 12.3 0.0 3.0 2 0 0 2 2 2 2 Homeobox KN domain zf-H2C2_5 PF13909.6 RJW69915.1 - 0.0012 18.5 7.2 0.0022 17.7 0.1 3.3 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-met PF12874.7 RJW69915.1 - 0.0014 18.9 0.8 0.0014 18.9 0.8 4.9 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 RJW69915.1 - 0.0058 17.0 0.4 0.0058 17.0 0.4 4.4 4 0 0 4 4 4 1 Zinc finger, C2H2 type Homez PF11569.8 RJW69915.1 - 0.013 15.0 0.0 0.55 9.7 0.0 2.6 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez DUF4709 PF15821.5 RJW69915.1 - 0.16 12.2 1.2 0.7 10.2 1.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Vps36-NZF-N PF16988.5 RJW69915.1 - 0.3 10.5 4.9 3.2 7.2 0.0 3.8 4 0 0 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DnaJ PF00226.31 RJW69916.1 - 1.5e-18 66.6 0.1 2.2e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain TCR PF03638.15 RJW69917.1 - 5.3e-24 84.2 55.0 3.4e-12 46.5 23.1 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 RJW69917.1 - 0.0024 18.0 45.9 0.011 15.9 18.8 2.6 2 0 0 2 2 2 2 CXC domain of E3 ubiquitin-protein ligase MSL2 DUF4200 PF13863.6 RJW69919.1 - 1.8e-25 89.7 11.4 1.8e-25 89.7 11.4 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF4200) Sacchrp_dh_NADP PF03435.18 RJW69919.1 - 1.1 9.6 4.1 0.61 10.3 0.1 2.6 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Myb_DNA-bind_5 PF13873.6 RJW69920.1 - 2.4e-09 37.2 2.7 6.5e-09 35.8 2.7 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RJW69920.1 - 0.0035 17.7 0.1 0.0074 16.6 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RJW69920.1 - 0.044 14.1 0.5 0.11 12.9 0.5 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Maelstrom PF13017.6 RJW69921.1 - 0.12 12.1 1.1 0.24 11.0 1.1 1.5 1 0 0 1 1 1 0 piRNA pathway germ-plasm component Zds_C PF08632.10 RJW69921.1 - 0.22 11.3 1.6 39 4.1 0.0 3.9 4 0 0 4 4 4 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Aminotran_1_2 PF00155.21 RJW69922.1 - 8e-34 117.4 0.0 9.8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Transposase_22 PF02994.14 RJW69924.1 - 0.039 14.1 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 L1 transposable element RBD-like domain Ribosomal_L3 PF00297.22 RJW69925.1 - 2.8e-170 566.2 13.1 6.8e-170 565.0 13.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L3 zf-C2H2 PF00096.26 RJW69927.1 - 2.8e-15 55.8 49.0 0.01 16.2 0.3 8.1 8 1 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW69927.1 - 4.1e-12 45.8 52.1 0.025 15.4 0.4 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger FOXP-CC PF16159.5 RJW69927.1 - 2.3e-06 28.1 25.1 0.94 10.2 0.1 7.3 4 1 4 8 8 8 5 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 RJW69927.1 - 3.5e-06 27.2 48.7 0.0039 17.6 0.4 7.7 8 0 0 8 8 8 4 Zinc-finger double domain zf-TRAF PF02176.18 RJW69927.1 - 0.00019 22.0 29.4 0.11 13.2 1.6 4.6 4 0 0 4 4 4 3 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 RJW69927.1 - 0.013 15.7 5.0 16 5.9 0.1 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RJW69927.1 - 0.12 12.2 0.2 0.12 12.2 0.2 6.3 7 1 0 7 7 7 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 RJW69927.1 - 9.5 6.3 27.0 12 6.0 0.5 5.9 2 2 4 6 6 6 0 Aberrant zinc-finger Exo_endo_phos PF03372.23 RJW69928.1 - 7.9e-22 77.9 0.5 1.2e-21 77.3 0.5 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ABC2_membrane_3 PF12698.7 RJW69928.1 - 3.3 6.7 10.0 4.5 6.3 4.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein CH_2 PF06294.11 RJW69930.1 - 1.8e-31 108.1 0.2 3.5e-31 107.2 0.2 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 RJW69930.1 - 4.9e-12 45.5 0.0 8.3e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 RJW69930.1 - 0.042 14.0 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 Calponin homology (CH) domain Cys_Met_Meta_PP PF01053.20 RJW69932.1 - 1.2e-129 432.3 0.0 1.3e-129 432.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RJW69932.1 - 0.0042 16.3 0.0 0.0074 15.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 RJW69932.1 - 0.024 13.1 0.0 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Aminotran_5 PF00266.19 RJW69932.1 - 0.12 11.3 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V GDC-P PF02347.16 RJW69932.1 - 0.19 10.5 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Mito_morph_reg PF14972.6 RJW69933.1 - 1.6e-38 131.9 0.4 1.8e-31 108.9 0.1 2.6 2 1 0 2 2 2 2 Mitochondrial morphogenesis regulator RRM_1 PF00076.22 RJW69934.1 - 2.1e-18 65.9 0.1 4.5e-18 64.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RJW69934.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HEPN_AbiU2 PF18734.1 RJW69934.1 - 0.066 12.7 0.5 0.098 12.2 0.5 1.2 1 0 0 1 1 1 0 AbiU2 zf-CCHC PF00098.23 RJW69935.1 - 0.0011 18.9 37.5 0.12 12.4 1.2 5.4 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.6 RJW69935.1 - 0.063 13.3 0.6 0.063 13.3 0.6 4.6 3 1 2 5 5 5 0 Zinc knuckle XPA_N PF01286.18 RJW69935.1 - 8.1 6.6 7.6 12 6.0 1.6 2.7 2 0 0 2 2 2 0 XPA protein N-terminal MFS_1 PF07690.16 RJW69938.1 - 1.9e-35 122.4 33.5 1.6e-32 112.8 26.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 RJW69938.1 - 0.00077 18.4 4.0 0.00077 18.4 4.0 1.9 2 1 0 2 2 2 1 LacY proton/sugar symporter MFS_1_like PF12832.7 RJW69938.1 - 7.7 5.3 19.9 0.1 11.4 5.5 2.2 1 1 1 2 2 2 0 MFS_1 like family RRM_1 PF00076.22 RJW69939.1 - 6.7e-15 54.7 0.2 0.00039 20.2 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RJW69939.1 - 0.0093 16.0 0.1 3.2 7.9 0.1 3.1 2 1 0 2 2 2 2 Limkain b1 Ceramidase_alk PF04734.13 RJW69940.1 - 4.5e-221 734.9 0.0 5.3e-221 734.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 RJW69940.1 - 3.7e-46 157.1 0.0 6.6e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal 7tm_1 PF00001.21 RJW69941.1 - 4.8e-07 29.4 20.7 2.3e-05 23.9 20.7 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW69941.1 - 0.0006 19.5 6.3 0.0006 19.5 6.3 2.7 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 RJW69941.1 - 0.85 9.6 10.5 0.034 14.1 3.4 2.1 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa EF-hand_2 PF09068.11 RJW69942.1 - 2.8e-49 166.4 0.0 7.4e-49 165.0 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 RJW69942.1 - 3.2e-26 91.6 0.0 7.9e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand ZZ PF00569.17 RJW69942.1 - 4.7e-10 39.1 6.9 1e-09 38.0 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 RJW69942.1 - 0.00014 22.1 2.3 0.0003 21.0 2.3 1.6 1 0 0 1 1 1 1 C1 domain WW PF00397.26 RJW69942.1 - 0.00068 19.7 3.2 0.0017 18.4 3.2 1.8 1 0 0 1 1 1 1 WW domain PI_PP_I PF18363.1 RJW69942.1 - 3.3 7.9 5.3 45 4.3 0.0 4.1 4 0 0 4 4 4 0 Phosphoinositide phosphatase insertion domain NRDE-2 PF08424.10 RJW69943.1 - 1e-67 228.6 0.1 3.9e-67 226.7 0.0 2.0 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference GPS2_interact PF15784.5 RJW69944.1 - 0.12 12.8 1.3 0.55 10.7 1.3 2.2 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain EMP24_GP25L PF01105.24 RJW69944.1 - 3.8 7.4 4.9 1.6 8.6 1.2 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD V-set PF07686.17 RJW69947.1 - 0.0009 19.4 0.0 0.013 15.6 0.0 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 RJW69947.1 - 0.02 14.9 0.1 0.07 13.2 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW69947.1 - 0.066 13.8 0.0 0.57 10.8 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain DUF4503 PF14951.6 RJW69949.1 - 0.00049 18.7 0.2 0.00087 17.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) DUF587 PF04532.12 RJW69949.1 - 0.0042 16.4 0.1 0.0098 15.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF587) Alpha_E1_glycop PF01589.16 RJW69949.1 - 0.1 11.2 0.0 0.26 9.9 0.0 1.5 2 0 0 2 2 2 0 Alphavirus E1 glycoprotein SRTM1 PF15872.5 RJW69950.1 - 0.031 14.4 0.4 0.082 13.1 0.2 1.8 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Polysacc_synt PF01943.17 RJW69950.1 - 0.038 13.4 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RRM_1 PF00076.22 RJW69951.1 - 2.9e-08 33.4 0.3 0.00011 22.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NTF-like PF14540.6 RJW69952.1 - 0.077 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase-like LIM PF00412.22 RJW69955.1 - 6.2e-61 202.5 82.2 9.4e-13 48.2 6.1 6.8 6 0 0 6 6 6 6 LIM domain PET PF06297.14 RJW69955.1 - 0.00034 20.8 0.1 0.0047 17.2 0.0 2.4 1 1 1 2 2 2 1 PET Domain TraA PF05513.11 RJW69955.1 - 6.4 7.2 5.4 11 6.4 5.4 1.3 1 0 0 1 1 1 0 TraA Pkinase PF00069.25 RJW69956.1 - 2.3e-71 240.3 0.0 2.7e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69956.1 - 1.5e-29 103.1 0.0 2.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW69956.1 - 6.1e-07 28.7 0.1 8.8e-07 28.2 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RJW69956.1 - 2.5e-06 27.0 0.2 4.2e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RJW69956.1 - 5.7e-05 22.6 0.1 0.14 11.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 RJW69956.1 - 7.8e-05 22.7 0.0 0.2 11.6 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 RJW69956.1 - 0.0026 17.4 0.5 0.0066 16.1 0.5 1.6 1 1 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 RJW69956.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cas9_b_hairpin PF17893.1 RJW69956.1 - 0.093 12.5 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain C2 PF00168.30 RJW69958.1 - 1.2e-10 41.6 0.0 2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain CUE PF02845.16 RJW69958.1 - 1.9e-06 27.5 0.1 3.3e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 CUE domain MULE PF10551.9 RJW69959.1 - 3.1e-17 62.8 0.4 7.9e-17 61.5 0.1 1.8 2 0 0 2 2 2 1 MULE transposase domain CI-B14_5a PF07347.12 RJW69960.1 - 9.6e-32 108.7 0.5 1.1e-31 108.6 0.5 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) EB1 PF03271.17 RJW69961.1 - 1.2e-13 51.0 1.4 2.8e-13 49.8 0.8 2.0 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 RJW69961.1 - 4e-12 46.3 0.2 6.6e-12 45.6 0.2 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW69961.1 - 0.0025 17.6 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain Cep57_CLD_2 PF14197.6 RJW69961.1 - 0.015 15.4 0.5 0.025 14.7 0.5 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CH_2 PF06294.11 RJW69961.1 - 0.085 13.0 0.5 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 CH-like domain in sperm protein DUF2407_C PF13373.6 RJW69961.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF3232 PF11554.8 RJW69961.1 - 0.17 12.2 0.5 9.5 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) Peptidase_S11 PF00768.20 RJW69962.1 - 0.031 13.7 0.1 0.56 9.6 0.2 1.9 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase RVT_1 PF00078.27 RJW69963.1 - 0.00042 19.9 0.0 0.00066 19.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DcpS_C PF11969.8 RJW69964.1 - 4.9e-23 81.8 0.0 1.2e-22 80.5 0.0 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 RJW69964.1 - 5.4e-12 46.5 0.0 1.6e-11 45.0 0.0 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal NTR PF01759.21 RJW69965.1 - 5.3e-10 39.1 0.0 4.8e-08 32.8 0.0 2.7 3 0 0 3 3 3 2 UNC-6/NTR/C345C module Pkinase PF00069.25 RJW69968.1 - 4.4e-54 183.6 0.0 5.5e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW69968.1 - 1.1e-27 97.0 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW69968.1 - 2e-06 27.4 0.0 2.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW69968.1 - 0.11 11.5 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Laminin_N PF00055.17 RJW69969.1 - 1.6e-46 158.8 0.1 1.6e-46 158.8 0.1 2.5 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 RJW69969.1 - 7.3e-20 70.9 70.0 3.1e-09 36.8 13.0 5.0 5 1 0 5 5 5 3 Laminin EGF domain BNR_6 PF15899.5 RJW69969.1 - 0.012 15.5 1.6 0.017 15.1 0.2 2.0 2 0 0 2 2 2 0 BNR-Asp box repeat BNR PF02012.20 RJW69969.1 - 0.05 13.6 0.1 0.36 11.0 0.1 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat WD40 PF00400.32 RJW69972.1 - 1.3e-11 44.8 10.2 0.01 16.7 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 RJW69972.1 - 0.00022 20.0 0.5 0.095 11.3 0.2 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Marek_SORF3 PF07153.11 RJW69972.1 - 0.032 13.6 0.0 0.063 12.6 0.0 1.5 1 1 0 1 1 1 0 Marek's disease-like virus SORF3 protein PDZ PF00595.24 RJW69973.1 - 3.5e-06 27.3 0.0 4.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW69973.1 - 0.0039 17.5 0.0 0.0045 17.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW69973.1 - 0.0043 16.9 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF1736 PF08409.11 RJW69974.1 - 2.2e-25 88.4 0.3 2.2e-25 88.4 0.3 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.6 RJW69974.1 - 3e-14 52.3 0.3 0.0045 17.3 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RJW69974.1 - 1.1e-13 50.6 1.5 0.00071 19.2 0.1 4.7 2 2 2 4 4 4 4 TPR repeat TPR_8 PF13181.6 RJW69974.1 - 2.7e-12 45.9 0.6 0.00054 20.0 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW69974.1 - 2.2e-11 42.9 6.0 6.4e-05 22.8 0.0 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RJW69974.1 - 2.4e-11 43.0 6.0 5.4e-07 29.2 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW69974.1 - 2.9e-11 43.2 1.9 0.0025 18.5 0.0 5.2 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 RJW69974.1 - 1.1e-10 41.9 1.7 0.0022 18.4 0.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW69974.1 - 3.4e-10 40.4 1.5 0.00049 20.7 0.4 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW69974.1 - 2.9e-09 37.1 0.5 0.001 19.3 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW69974.1 - 1e-07 31.5 2.6 0.016 15.2 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 RJW69974.1 - 0.00024 20.8 11.1 0.088 12.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RJW69974.1 - 0.0005 20.2 0.0 0.01 16.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW69974.1 - 0.00072 19.7 0.0 0.32 11.2 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 PMT_2 PF13231.6 RJW69974.1 - 0.0047 17.2 5.1 0.0047 17.2 5.1 3.1 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_6 PF13174.6 RJW69974.1 - 0.04 14.6 3.0 7.1 7.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 RJW69974.1 - 0.09 12.0 0.1 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 RJW69974.1 - 0.19 11.4 0.1 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain SHNi-TPR PF10516.9 RJW69976.1 - 9e-09 34.6 0.8 2.2e-08 33.4 0.8 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.6 RJW69976.1 - 1.5e-08 34.8 0.3 3.2e-08 33.7 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 RJW69976.1 - 1.7e-05 24.5 0.1 0.00015 21.6 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW69976.1 - 0.002 18.1 0.1 0.93 9.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RJW69976.1 - 0.0028 17.4 0.1 0.35 10.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat PikAIV_N PF18605.1 RJW69976.1 - 0.0072 15.9 2.0 0.0088 15.6 0.6 1.9 2 0 0 2 2 2 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Spc29 PF17082.5 RJW69976.1 - 0.008 16.0 2.2 0.008 16.0 2.2 1.8 2 1 0 2 2 2 1 Spindle Pole Component 29 TPR_8 PF13181.6 RJW69976.1 - 0.04 14.1 0.1 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Tup_N PF08581.10 RJW69976.1 - 0.063 13.6 0.4 0.063 13.6 0.4 2.9 2 1 1 3 3 3 0 Tup N-terminal Med9 PF07544.13 RJW69976.1 - 0.11 12.6 3.9 3.3 7.9 0.1 3.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 RED_C PF07807.11 RJW69976.1 - 0.19 12.2 5.7 0.31 11.5 2.3 2.5 2 1 1 3 3 3 0 RED-like protein C-terminal region NPV_P10 PF05531.12 RJW69976.1 - 0.64 10.5 10.8 0.085 13.3 2.4 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Glyco_hydro_47 PF01532.20 RJW69977.1 - 1.1e-134 449.8 0.0 1.3e-134 449.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 RJW69977.1 - 0.073 12.1 0.1 1.7 7.6 0.0 2.5 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 NDUF_B4 PF07225.12 RJW69979.1 - 1.9e-14 53.6 0.0 2.2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Yippee-Mis18 PF03226.14 RJW69981.1 - 3.1e-08 33.8 0.2 5.3e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LON_substr_bdg PF02190.16 RJW69981.1 - 0.00069 19.6 0.0 0.03 14.2 0.0 2.4 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain Arginase PF00491.21 RJW69982.1 - 3.6e-59 200.6 0.1 4.1e-59 200.4 0.1 1.0 1 0 0 1 1 1 1 Arginase family Arginase PF00491.21 RJW69983.1 - 1.7e-66 224.6 0.1 2.1e-66 224.3 0.1 1.1 1 0 0 1 1 1 1 Arginase family zf-RING_11 PF17123.5 RJW69984.1 - 0.15 11.8 2.4 0.38 10.5 2.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger Frag1 PF10277.9 RJW69985.1 - 4.1e-38 131.1 13.3 4.7e-38 130.9 13.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 RJW69985.1 - 0.16 11.6 13.4 1.1 8.9 13.3 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Bax1-I PF01027.20 RJW69985.1 - 0.45 10.3 17.6 0.064 13.1 10.0 2.7 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Virul_fac_BrkB PF03631.15 RJW69985.1 - 1 8.9 9.5 0.46 10.1 3.7 2.4 2 1 0 2 2 2 0 Virulence factor BrkB GTP_EFTU PF00009.27 RJW69986.1 - 1.9e-43 148.3 0.0 2.8e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RJW69986.1 - 1.9e-17 63.6 0.0 3.6e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 RJW69986.1 - 2e-06 27.9 0.5 0.017 15.2 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase G-alpha PF00503.20 RJW69986.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit FeoB_N PF02421.18 RJW69986.1 - 0.25 10.8 0.3 15 5.1 0.0 2.8 2 1 1 3 3 3 0 Ferrous iron transport protein B DIX PF00778.17 RJW69988.1 - 6e-18 64.5 0.1 1.1e-15 57.2 0.0 3.0 2 1 0 2 2 2 1 DIX domain RGS PF00615.19 RJW69988.1 - 4.5e-12 46.3 2.9 1.7e-11 44.4 2.9 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.10 RJW69988.1 - 0.011 15.8 3.4 0.012 15.6 0.2 2.6 2 0 0 2 2 2 0 Axin beta-catenin binding domain DSHCT PF08148.12 RJW69989.1 - 7.9e-38 129.7 0.1 2e-37 128.4 0.1 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 RJW69989.1 - 7.6e-17 61.6 0.1 1.8e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RJW69989.1 - 4.5e-09 36.5 0.0 8.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RJW69989.1 - 6.2e-05 23.3 0.0 0.00017 21.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RJW69989.1 - 0.0036 17.6 1.1 0.014 15.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 RJW69989.1 - 0.038 13.5 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 RJW69989.1 - 0.058 13.4 0.2 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain BAG6 PF12057.8 RJW69989.1 - 0.13 11.9 0.3 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 BCL2-associated athanogene 6 Exonuc_VII_L PF02601.15 RJW69989.1 - 0.86 9.1 3.2 0.65 9.5 0.0 2.3 3 0 0 3 3 3 0 Exonuclease VII, large subunit Pacs-1 PF10254.9 RJW69990.1 - 2.4e-37 128.9 0.0 1.1e-16 60.8 0.0 3.3 3 0 0 3 3 3 3 PACS-1 cytosolic sorting protein TPR_2 PF07719.17 RJW69991.1 - 0.00072 19.5 0.4 0.28 11.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat SNARE_assoc PF09335.11 RJW69991.1 - 0.099 13.1 0.2 19 5.7 0.0 2.7 2 0 0 2 2 2 0 SNARE associated Golgi protein CCB1 PF12046.8 RJW69991.1 - 3.3 7.0 7.2 7.2 5.9 0.1 2.3 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B tRNA-synt_1 PF00133.22 RJW69992.1 - 5.5e-39 133.9 0.0 6.6e-18 64.3 0.0 3.3 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RJW69992.1 - 2.8e-16 59.2 0.0 1.4e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 RJW69992.1 - 7.9e-10 38.9 0.1 1.5e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 RJW69992.1 - 1.8e-07 30.8 0.0 3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain MMR_HSR1 PF01926.23 RJW69993.1 - 5.7e-20 71.5 0.0 1.1e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RJW69993.1 - 1.5e-09 37.5 0.3 4e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RJW69993.1 - 1.5e-06 28.3 0.1 0.016 15.2 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 RJW69993.1 - 2.9e-06 26.8 0.1 5e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 RJW69993.1 - 1.2e-05 24.9 0.6 0.00065 19.3 0.6 3.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RJW69993.1 - 0.00025 21.0 0.1 0.077 12.9 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase Arf PF00025.21 RJW69993.1 - 0.00027 20.4 0.5 0.0017 17.8 0.2 2.3 2 1 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 RJW69993.1 - 0.0022 18.2 0.1 0.0059 16.8 0.1 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 RJW69993.1 - 0.0037 17.5 0.0 0.05 13.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain Ras PF00071.22 RJW69993.1 - 0.005 16.5 0.1 0.3 10.7 0.0 2.3 2 0 0 2 2 2 1 Ras family PduV-EutP PF10662.9 RJW69993.1 - 0.026 14.2 0.0 2.8 7.7 0.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 RJW69993.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) LRR_9 PF14580.6 RJW69994.1 - 9e-15 54.6 2.1 4.5e-14 52.3 2.0 2.2 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 RJW69994.1 - 9.1e-12 45.0 10.3 1.5e-06 28.4 1.9 3.8 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW69994.1 - 1e-06 28.4 11.7 4.1e-05 23.2 5.0 3.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 RJW69994.1 - 0.072 13.7 9.8 32 5.6 0.0 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 RJW69994.1 - 0.12 12.5 6.5 9.7 6.5 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeat Tektin PF03148.14 RJW69998.1 - 1.3e-111 373.0 34.8 1.5e-111 372.9 34.8 1.0 1 0 0 1 1 1 1 Tektin family DUF948 PF06103.11 RJW69998.1 - 0.15 12.3 9.1 6.3 7.1 0.2 4.1 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 RJW69998.1 - 0.24 11.5 14.2 0.4 10.7 0.6 4.0 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 RJW69998.1 - 0.56 10.7 21.7 0.13 12.7 2.3 4.4 4 1 0 4 4 4 0 Snapin/Pallidin DUF1664 PF07889.12 RJW69998.1 - 0.81 9.7 19.5 0.69 10.0 0.2 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) CdvA PF18822.1 RJW69998.1 - 0.92 9.3 0.0 0.92 9.3 0.0 4.3 4 1 0 4 4 4 0 CdvA-like coiled-coil domain LLGL PF08366.13 RJW69999.1 - 3e-24 85.4 0.0 6.5e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 LLGL2 PQQ_3 PF13570.6 RJW69999.1 - 0.038 14.5 1.4 0.67 10.5 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain RVT_1 PF00078.27 RJW70002.1 - 0.029 13.9 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PCMT PF01135.19 RJW70003.1 - 2.2e-72 243.2 0.0 2.8e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 RJW70003.1 - 0.00084 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW70003.1 - 0.0011 19.6 0.0 0.0029 18.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW70003.1 - 0.0013 18.5 0.0 0.0039 17.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 RJW70003.1 - 0.0016 18.6 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 RJW70003.1 - 0.0075 16.9 0.0 0.024 15.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 RJW70003.1 - 0.044 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RJW70003.1 - 0.048 13.2 0.1 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase small domain GCD14 PF08704.10 RJW70003.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 RJW70003.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF3325 PF11804.8 RJW70003.1 - 3.2 7.9 6.6 3.6 7.8 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) NDUFB10 PF10249.9 RJW70004.1 - 8.2e-52 175.0 5.4 1.2e-51 174.4 5.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 MAPKK1_Int PF08923.10 RJW70006.1 - 2.1e-22 79.1 0.0 2.5e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting MRP-S28 PF10213.9 RJW70007.1 - 1.2e-11 45.2 0.0 4.2e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Asp PF00026.23 RJW70008.1 - 1.3e-55 189.1 0.0 9.3e-49 166.5 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW70008.1 - 1.3e-05 25.6 0.1 0.0002 21.7 0.0 2.6 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RJW70008.1 - 1.4e-05 25.6 0.0 1.2 9.9 0.0 3.6 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 RJW70008.1 - 0.00015 21.6 0.0 0.16 11.7 0.0 2.6 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 RJW70008.1 - 0.015 15.8 0.0 66 4.2 0.0 4.1 4 1 0 4 4 4 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 RJW70009.1 - 8.2e-20 71.4 0.0 1.2e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 RJW70009.1 - 0.0011 19.5 0.0 1.5 9.5 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 RJW70009.1 - 0.025 15.1 0.0 12 6.5 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 RJW70009.1 - 0.028 14.7 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease TPR_12 PF13424.6 RJW70010.1 - 5e-14 52.3 6.6 3.5e-09 36.8 0.8 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW70010.1 - 4.9e-08 32.5 6.3 0.02 15.0 0.8 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW70010.1 - 1e-07 31.7 8.0 0.00092 18.7 2.9 2.9 1 1 1 3 3 3 2 MalT-like TPR region TPR_1 PF00515.28 RJW70010.1 - 4e-06 26.4 5.7 0.086 12.7 0.5 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RJW70010.1 - 5.9e-06 26.1 4.9 2.3 8.7 0.5 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 RJW70010.1 - 0.00046 20.0 3.8 8.3 6.4 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW70010.1 - 0.0025 18.5 7.5 3.8 8.6 0.0 4.9 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW70010.1 - 0.011 16.2 13.3 0.37 11.3 0.7 5.0 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW70010.1 - 0.045 13.8 1.6 39 4.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Telomere_reg-2 PF10193.9 RJW70010.1 - 0.057 13.9 3.3 0.9 10.0 0.6 2.8 2 1 0 2 2 2 0 Telomere length regulation protein TPR_11 PF13414.6 RJW70010.1 - 0.063 13.0 0.5 19 5.0 0.1 3.7 4 0 0 4 4 4 0 TPR repeat ANAPC3 PF12895.7 RJW70010.1 - 0.25 11.6 9.3 0.26 11.6 4.2 3.3 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Mt_ATP-synt_B PF05405.14 RJW70011.1 - 2.8e-33 114.8 0.1 4.8e-33 114.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) V-ATPase_G_2 PF16999.5 RJW70011.1 - 0.00053 20.4 2.6 0.00053 20.4 2.6 2.0 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit Mitofilin PF09731.9 RJW70011.1 - 0.0011 18.0 1.6 0.0011 18.0 1.6 1.7 2 0 0 2 2 2 1 Mitochondrial inner membrane protein Prefoldin_3 PF13758.6 RJW70011.1 - 0.0017 18.3 1.6 0.0042 17.1 1.6 1.7 1 0 0 1 1 1 1 Prefoldin subunit ANAPC5 PF12862.7 RJW70011.1 - 0.11 12.6 0.6 3.5 7.8 0.6 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 Taxilin PF09728.9 RJW70012.1 - 2.3e-76 256.9 63.0 3.1e-76 256.5 63.0 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Filament PF00038.21 RJW70012.1 - 2.2 7.8 53.4 3.9e+02 0.4 53.4 3.4 1 1 0 1 1 1 0 Intermediate filament protein Laminin_II PF06009.12 RJW70012.1 - 2.7 8.0 31.3 1.8 8.6 5.3 3.7 1 1 2 3 3 3 0 Laminin Domain II CPT_N PF16484.5 RJW70013.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus INCENP_ARK-bind PF03941.15 RJW70016.1 - 0.097 12.6 0.7 0.097 12.6 0.7 2.3 4 0 0 4 4 4 0 Inner centromere protein, ARK binding region I-set PF07679.16 RJW70017.1 - 4.3e-15 55.6 0.0 7.4e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW70017.1 - 2.3e-13 50.5 0.0 6.4e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RJW70017.1 - 1.2e-09 38.4 0.0 4.4e-09 36.5 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RJW70017.1 - 1.3e-08 34.9 0.0 3.9e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RJW70017.1 - 0.00065 19.8 0.1 0.019 15.2 0.1 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain DUF1494 PF07379.11 RJW70017.1 - 0.022 14.6 0.0 0.055 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1494) Ig_5 PF16681.5 RJW70017.1 - 0.071 13.5 0.0 0.22 11.9 0.0 1.8 1 1 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain EGF_2 PF07974.13 RJW70017.1 - 0.64 10.4 9.3 0.44 11.0 4.8 2.7 2 0 0 2 2 2 0 EGF-like domain Amino_oxidase PF01593.24 RJW70020.1 - 2.8e-83 280.7 0.2 7.3e-33 114.5 0.1 4.3 3 1 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RJW70020.1 - 2.9e-11 43.4 0.1 7.2e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RJW70020.1 - 3.1e-06 27.0 0.5 6.3e-06 26.0 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 RJW70020.1 - 7.7e-06 26.4 0.2 2.6e-05 24.7 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RJW70020.1 - 1.1e-05 24.4 0.0 2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 RJW70020.1 - 1.1e-05 24.8 0.2 2.7e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 RJW70020.1 - 4.5e-05 22.8 0.0 8.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RJW70020.1 - 0.00015 21.1 0.6 0.00028 20.2 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 RJW70020.1 - 0.00031 20.0 0.1 0.0005 19.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 RJW70020.1 - 0.00057 19.3 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 RJW70020.1 - 0.001 18.5 0.1 0.0016 17.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 RJW70020.1 - 0.011 14.8 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 RJW70020.1 - 0.052 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein YqjK PF13997.6 RJW70020.1 - 0.13 12.5 0.1 0.42 10.9 0.0 2.0 2 0 0 2 2 1 0 YqjK-like protein NAD_binding_9 PF13454.6 RJW70020.1 - 0.13 12.2 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Tospo_nucleocap PF01533.16 RJW70020.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Tospovirus nucleocapsid protein EAP30 PF04157.16 RJW70021.1 - 2.6e-33 115.3 0.7 4.9e-33 114.4 0.7 1.5 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 RJW70021.1 - 1.3e-12 47.7 0.0 2.4e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 HTH_24 PF13412.6 RJW70021.1 - 0.0044 16.6 0.2 0.0092 15.5 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 RJW70021.1 - 0.15 11.9 0.5 0.5 10.3 0.5 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Focadhesin PF11229.8 RJW70022.1 - 0.14 10.4 0.1 0.14 10.3 0.1 1.0 1 0 0 1 1 1 0 Focadhesin Asp PF00026.23 RJW70024.1 - 4.7e-20 72.2 0.0 6.2e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 RJW70024.1 - 0.0033 18.0 0.0 0.066 13.9 0.0 2.5 2 1 0 2 2 2 1 Aspartyl protease Pkinase PF00069.25 RJW70026.1 - 1.6e-41 142.4 0.1 2.5e-40 138.5 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW70026.1 - 2.4e-18 66.4 0.0 3.5e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW70026.1 - 0.014 14.7 0.0 0.035 13.4 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Lon_2 PF13337.6 RJW70026.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease Sec7 PF01369.20 RJW70029.1 - 3.3e-53 180.1 0.1 4.7e-53 179.6 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 RJW70029.1 - 2.1e-18 66.7 0.0 3.5e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RJW70029.1 - 8.2e-08 32.6 0.1 1.8e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 RJW70029.1 - 0.00051 20.1 0.0 0.0015 18.6 0.0 1.8 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 RJW70029.1 - 0.0015 18.8 0.0 0.022 15.0 0.0 2.3 1 1 1 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 RJW70029.1 - 0.11 12.7 0.0 0.62 10.4 0.0 2.0 1 1 1 2 2 2 0 Pleckstrin homology domain YppG PF14179.6 RJW70031.1 - 0.019 15.6 0.8 0.028 15.1 0.8 1.2 1 0 0 1 1 1 0 YppG-like protein Cystatin PF00031.21 RJW70031.1 - 0.041 14.1 0.1 0.064 13.5 0.1 1.5 1 1 0 1 1 1 0 Cystatin domain SQAPI PF16845.5 RJW70031.1 - 0.051 13.9 0.0 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor SAM_2 PF07647.17 RJW70032.1 - 0.0004 20.4 0.0 0.044 13.9 0.0 3.0 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RJW70032.1 - 0.11 13.0 0.2 4.6 7.8 0.0 3.3 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) Asp PF00026.23 RJW70034.1 - 4.5e-17 62.5 0.0 1.3e-16 60.9 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 RJW70034.1 - 0.00031 21.3 0.0 0.065 13.9 0.0 3.3 2 2 0 2 2 2 1 Aspartyl protease RVP PF00077.20 RJW70034.1 - 0.0082 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 RJW70034.1 - 0.044 14.3 0.0 0.48 11.0 0.0 2.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease adh_short_C2 PF13561.6 RJW70035.1 - 1.9e-48 165.1 0.1 2.4e-48 164.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RJW70035.1 - 9e-36 123.2 0.8 1.3e-35 122.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RJW70035.1 - 3.3e-09 36.9 0.2 4.9e-09 36.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 RJW70035.1 - 4.3e-05 22.8 0.7 5.1e-05 22.6 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RJW70035.1 - 0.0048 16.0 0.2 0.0078 15.2 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 RJW70035.1 - 0.0091 15.5 0.1 0.015 14.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 RJW70035.1 - 0.011 15.7 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 RJW70035.1 - 0.026 13.8 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 RJW70035.1 - 0.026 14.9 0.1 0.05 14.0 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 RJW70035.1 - 0.028 15.0 0.3 0.058 14.0 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 RJW70035.1 - 0.14 12.1 0.9 0.9 9.5 0.7 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RRM_5 PF13893.6 RJW70036.1 - 4.7e-34 116.7 0.0 2e-28 98.5 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RJW70036.1 - 1e-18 66.9 0.0 1.6e-06 27.9 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RJW70036.1 - 2.8e-09 37.1 0.0 5.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 RJW70036.1 - 0.0012 18.7 0.0 2.8 7.9 0.0 3.1 3 1 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 RJW70036.1 - 0.014 15.5 0.0 23 5.2 0.0 3.4 3 0 0 3 3 3 0 Limkain b1 RL PF17797.1 RJW70036.1 - 0.057 13.4 0.0 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 RL domain tRNA-synt_2d PF01409.20 RJW70037.1 - 5.2e-88 294.7 0.0 6.9e-88 294.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 RJW70037.1 - 3.5e-17 61.9 2.1 3.9e-17 61.8 1.0 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 RJW70037.1 - 1.4e-13 50.9 0.0 5.5e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 RJW70037.1 - 6e-06 25.9 0.0 0.002 17.6 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 RJW70037.1 - 9.6e-06 25.5 0.1 1.9e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 2 HTH_11 PF08279.12 RJW70037.1 - 0.00056 19.8 0.1 0.0013 18.6 0.1 1.6 1 0 0 1 1 1 1 HTH domain tRNA-synt_2 PF00152.20 RJW70037.1 - 0.00057 19.1 0.0 0.0035 16.5 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) MarR_2 PF12802.7 RJW70037.1 - 0.0024 17.7 0.1 0.0068 16.3 0.1 1.7 1 0 0 1 1 1 1 MarR family HTH_45 PF14947.6 RJW70037.1 - 0.027 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix MarR PF01047.22 RJW70037.1 - 0.041 13.8 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 MarR family XK-related PF09815.9 RJW70041.1 - 8.5e-08 31.6 11.0 3e-07 29.8 11.0 1.8 1 1 0 1 1 1 1 XK-related protein Homeodomain PF00046.29 RJW70043.1 - 1.2e-21 76.3 3.0 2.4e-21 75.3 3.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW70043.1 - 0.083 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain MRP-S33 PF08293.11 RJW70044.1 - 5.5e-18 65.0 0.5 7.2e-18 64.6 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 I-set PF07679.16 RJW70045.1 - 5.9e-36 122.4 0.0 5e-14 52.1 0.0 4.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW70045.1 - 1.8e-34 118.2 4.4 5.9e-13 49.2 0.0 5.2 4 0 0 4 4 4 3 Immunoglobulin domain fn3 PF00041.21 RJW70045.1 - 3e-32 110.8 39.8 5.1e-08 33.1 0.2 12.0 11 2 0 11 11 10 6 Fibronectin type III domain Ig_2 PF13895.6 RJW70045.1 - 3e-20 72.3 0.0 1.6e-06 28.3 0.0 4.0 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RJW70045.1 - 5.2e-15 55.4 0.0 0.00011 22.3 0.0 4.0 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 RJW70045.1 - 6.4e-07 29.4 0.2 2 8.5 0.0 3.9 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RJW70045.1 - 2.2e-06 27.8 0.8 0.029 14.6 0.0 4.6 4 1 0 4 4 4 2 Immunoglobulin V-set domain Insulin_TMD PF17870.1 RJW70045.1 - 0.0075 16.3 0.8 0.018 15.1 0.8 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Pur_ac_phosph_N PF16656.5 RJW70045.1 - 0.02 15.4 17.2 0.13 12.9 0.7 6.1 6 0 0 6 6 6 0 Purple acid Phosphatase, N-terminal domain Orf78 PF06024.12 RJW70045.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Ig_4 PF16680.5 RJW70045.1 - 0.13 12.6 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR2 PF02439.15 RJW70045.1 - 0.16 11.7 1.5 0.37 10.6 1.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 RJW70045.1 - 0.17 12.7 0.0 0.38 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 RJW70045.1 - 0.69 9.4 3.9 1.9 7.9 3.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Apt1 PF10351.9 RJW70046.1 - 3.2e-67 227.4 0.0 3.1e-39 135.2 0.0 4.3 4 1 1 5 5 5 3 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 RJW70046.1 - 5.7e-15 55.8 0.0 1.3e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 RJW70046.1 - 0.00021 21.2 0.1 0.0016 18.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_WPPW PF10359.9 RJW70046.1 - 0.008 15.1 1.9 0.034 13.0 0.0 2.4 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Abhydrolase_6 PF12697.7 RJW70046.1 - 0.056 14.0 0.1 0.056 14.0 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_M16_M PF16187.5 RJW70047.1 - 3.8e-18 65.8 0.1 7.1e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 RJW70047.1 - 5.8e-18 65.3 0.0 1.8e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RJW70047.1 - 0.00022 21.3 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Fra10Ac1 PF09725.9 RJW70048.1 - 1.4e-48 164.1 2.8 2.7e-48 163.1 2.8 1.5 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Asp PF00026.23 RJW70051.1 - 4.5e-35 121.6 0.0 5.7e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW70051.1 - 0.0067 16.2 0.0 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RJW70051.1 - 0.21 12.3 0.0 2.1 9.1 0.0 2.4 2 1 0 2 2 2 0 Aspartyl protease Y_phosphatase PF00102.27 RJW70053.1 - 1.6e-138 459.9 0.0 2.7e-84 282.4 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RJW70053.1 - 1e-07 32.2 0.2 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.20 RJW70053.1 - 1.5e-07 31.3 0.1 0.0025 17.6 0.0 2.7 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RJW70053.1 - 1.3e-05 25.3 0.0 0.21 11.7 0.0 3.4 3 0 0 3 3 3 2 Inositol hexakisphosphate Asp PF00026.23 RJW70054.1 - 0.00069 19.1 0.0 0.00069 19.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Kinesin PF00225.23 RJW70055.1 - 4.2e-77 259.3 0.1 7.8e-77 258.4 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RJW70055.1 - 1.1e-11 44.8 0.0 2.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding fn3 PF00041.21 RJW70056.1 - 2.9e-14 53.2 14.4 0.013 15.8 0.1 7.6 8 0 0 8 8 8 5 Fibronectin type III domain GldM_C PF12080.8 RJW70056.1 - 0.00023 21.5 8.2 3.2 7.9 0.1 5.0 4 1 2 6 6 6 3 GldM C-terminal domain IgG_binding_B PF01378.17 RJW70056.1 - 0.00049 20.1 1.6 24 5.1 0.0 4.5 4 0 0 4 4 4 1 B domain NUMOD1 PF07453.13 RJW70056.1 - 0.13 12.6 1.5 1.6e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 NUMOD1 domain CMV_1a_C PF12503.8 RJW70056.1 - 0.13 12.3 0.0 15 5.7 0.0 3.8 4 0 0 4 4 4 0 Cucumber mosaic virus 1a protein C terminal RhoGEF67_u1 PF16615.5 RJW70056.1 - 0.24 11.9 10.7 53 4.4 1.0 4.7 4 0 0 4 4 4 0 Unstructured region one on RhoGEF 6 and 7 zf-C2H2 PF00096.26 RJW70057.1 - 0.037 14.5 1.0 0.17 12.4 1.0 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-RanBP PF00641.18 RJW70057.1 - 0.072 12.4 3.0 0.2 11.0 3.0 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF4698 PF15769.5 RJW70059.1 - 5.4e-29 101.6 24.2 9.5e-27 94.2 18.5 3.1 3 1 0 3 3 3 2 Domain of unknown function (DUF4698) Lactamase_B PF00753.27 RJW70061.1 - 2.9e-07 30.7 2.8 2.1e-06 27.9 2.8 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RJW70061.1 - 7.7e-05 22.3 0.1 0.00014 21.5 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CMS1 PF14617.6 RJW70061.1 - 0.24 10.7 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Asp PF00026.23 RJW70062.1 - 4.9e-90 302.2 0.1 1.5e-50 172.4 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW70062.1 - 1.7e-08 34.9 3.6 0.00023 21.5 0.0 4.5 3 2 0 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RJW70062.1 - 0.00012 21.9 0.4 0.001 18.8 0.0 2.7 4 0 0 4 4 4 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RJW70062.1 - 0.00068 20.2 0.0 13 6.5 0.0 4.2 4 0 0 4 4 4 2 Aspartyl protease gag-asp_proteas PF13975.6 RJW70062.1 - 0.037 14.6 0.0 19 5.9 0.0 3.8 4 1 0 4 4 4 0 gag-polyprotein putative aspartyl protease TFIIA_gamma_N PF02268.16 RJW70062.1 - 0.063 13.3 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Complex1_LYR PF05347.15 RJW70063.1 - 1.5e-11 44.1 1.2 2.9e-11 43.2 1.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RJW70063.1 - 0.0058 17.3 1.5 0.0085 16.8 1.2 1.5 1 1 1 2 2 2 1 Complex1_LYR-like CENP-B_N PF04218.13 RJW70063.1 - 0.089 12.4 0.0 0.25 11.0 0.0 1.9 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Ank_2 PF12796.7 RJW70064.1 - 9e-22 77.5 0.8 5.8e-09 36.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW70064.1 - 7e-18 64.8 1.6 4.1e-08 33.6 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW70064.1 - 2e-17 63.0 1.3 1.5e-09 37.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RJW70064.1 - 1.5e-14 53.7 8.6 4.4e-06 26.9 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat PDZ_6 PF17820.1 RJW70064.1 - 1.1e-12 47.6 0.0 2.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Ank_3 PF13606.6 RJW70064.1 - 1.2e-12 46.8 8.5 0.00036 20.7 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat PDZ PF00595.24 RJW70064.1 - 4.1e-12 46.3 0.0 7.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW70064.1 - 3.7e-05 23.9 0.0 9.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 RJW70064.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain Asp PF00026.23 RJW70065.1 - 4.4e-34 118.3 0.0 5.5e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DHHC PF01529.20 RJW70067.1 - 2.2e-23 82.9 6.3 3.3e-23 82.3 6.3 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase RRM_5 PF13893.6 RJW70068.1 - 4.5e-29 100.6 0.0 1.4e-25 89.3 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RJW70068.1 - 2.2e-19 69.1 0.0 6.3e-05 22.7 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RJW70068.1 - 2.5e-08 34.0 0.0 5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 RJW70068.1 - 0.00029 20.6 0.0 2.3 8.1 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 RJW70068.1 - 0.02 14.9 0.0 0.47 10.6 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 RL PF17797.1 RJW70068.1 - 0.16 11.9 0.0 40 4.3 0.0 3.1 4 0 0 4 4 4 0 RL domain WD40 PF00400.32 RJW70069.1 - 9.2e-46 152.9 31.8 2.3e-07 31.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW70069.1 - 4.2e-09 36.6 0.4 0.19 12.0 0.0 4.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW70069.1 - 2.4e-05 23.2 7.4 0.049 12.3 0.1 5.0 3 1 2 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 RJW70069.1 - 0.0018 18.2 0.1 0.032 14.1 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RJW70069.1 - 0.0047 16.8 0.1 11 6.1 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 RJW70069.1 - 0.0059 15.2 0.0 0.14 10.7 0.1 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 RJW70069.1 - 0.099 11.6 0.0 22 3.9 0.0 3.3 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RJW70069.1 - 0.25 10.6 0.0 28 3.9 0.0 2.5 2 1 1 3 3 3 0 WD40-like domain adh_short PF00106.25 RJW70070.1 - 1.8e-31 109.1 1.8 1.4e-23 83.4 0.0 2.9 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RJW70070.1 - 9.2e-22 77.7 0.1 2.5e-16 59.9 0.0 2.8 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW70070.1 - 8.2e-05 22.6 0.2 0.0004 20.4 0.2 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RJW70070.1 - 0.012 15.5 0.1 2 8.3 0.0 2.6 2 1 1 3 3 3 0 NAD(P)H-binding PRKCSH_1 PF13015.6 RJW70071.1 - 1.2e-18 67.3 0.1 2e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 RJW70071.1 - 1.5e-08 35.5 0.3 1.5e-08 35.5 0.3 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Suf PF05843.14 RJW70071.1 - 1 9.3 5.6 1.5 8.7 5.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Cwf_Cwc_15 PF04889.12 RJW70071.1 - 1.1 8.9 10.7 1.6 8.4 10.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.17 RJW70071.1 - 5.2 5.7 6.9 6.7 5.4 6.9 1.1 1 0 0 1 1 1 0 Presenilin Tubulin PF00091.25 RJW70072.1 - 8.7e-61 205.6 0.0 1.2e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW70072.1 - 6.9e-44 149.0 0.0 1e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 RJW70074.1 - 4.8e-52 177.0 0.0 6.4e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW70074.1 - 8.5e-17 61.5 0.1 4.5e-11 43.0 0.0 2.4 1 1 1 2 2 2 2 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW70074.1 - 0.00016 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain FhuF_C PF11575.8 RJW70074.1 - 0.016 15.1 0.5 0.031 14.2 0.5 1.5 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain LSM14 PF12701.7 RJW70075.1 - 6.3e-11 42.2 0.1 1.7e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 RJW70075.1 - 4.1e-05 23.6 0.0 7.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain PHD PF00628.29 RJW70076.1 - 3.6e-06 26.8 9.5 7.2e-06 25.8 9.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 RJW70076.1 - 0.059 13.5 8.7 0.12 12.5 8.7 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 RJW70076.1 - 1.9 8.4 9.8 0.18 11.7 5.1 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tubulin_C PF03953.17 RJW70077.1 - 3.7e-38 130.5 0.0 5.7e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 RJW70077.1 - 5.7e-25 88.7 0.0 8.1e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain GN3L_Grn1 PF08701.11 RJW70079.1 - 2.7e-22 78.7 7.0 9.7e-22 76.9 7.0 2.0 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 RJW70079.1 - 3.4e-16 59.3 0.3 6.6e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RJW70079.1 - 2e-11 43.6 0.0 6.2e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 RJW70079.1 - 4.8e-07 30.0 0.9 0.21 11.6 0.1 3.4 2 2 1 3 3 3 3 Dynamin family RsgA_GTPase PF03193.16 RJW70079.1 - 6.9e-06 26.1 0.2 0.038 13.9 0.0 2.5 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 RJW70079.1 - 0.00018 20.9 0.1 0.00042 19.7 0.1 1.6 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 RJW70079.1 - 0.0018 17.9 0.1 0.036 13.6 0.0 2.6 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Virul_Fac PF10139.9 RJW70079.1 - 0.2 9.8 0.0 0.2 9.8 0.0 1.6 2 0 0 2 2 2 0 Putative bacterial virulence factor DUF716 PF04819.12 RJW70081.1 - 6.9e-18 64.6 5.3 1.3e-17 63.8 5.1 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF716) TCR PF03638.15 RJW70082.1 - 2.8e-23 81.9 46.9 1.4e-11 44.5 22.2 2.4 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Peptidase_C34 PF05413.11 RJW70082.1 - 0.1 12.9 4.9 0.05 13.9 1.7 2.1 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase MSL2-CXC PF16682.5 RJW70082.1 - 0.53 10.5 42.5 0.11 12.6 14.7 3.1 2 1 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 betaPIX_CC PF16523.5 RJW70082.1 - 1.6 8.6 5.6 2.3 8.1 1.5 2.3 2 0 0 2 2 2 0 betaPIX coiled coil Mem_trans PF03547.18 RJW70082.1 - 3.7 5.8 5.1 5.9 5.2 5.1 1.5 1 1 0 1 1 1 0 Membrane transport protein Aconitase PF00330.20 RJW70083.1 - 1.2e-149 499.3 0.0 1.6e-149 498.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RJW70083.1 - 3e-43 147.3 0.0 5.6e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Tubulin PF00091.25 RJW70084.1 - 2e-60 204.4 0.0 2.9e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW70084.1 - 1.8e-49 167.1 0.0 3.4e-49 166.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW70084.1 - 0.033 13.9 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain TRAPP PF04051.16 RJW70088.1 - 1.9e-18 66.6 0.0 2e-18 66.5 0.0 1.2 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component eIF_4EBP PF05456.11 RJW70089.1 - 2.7e-36 124.0 0.6 3.1e-36 123.8 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF782 PF05614.11 RJW70091.1 - 0.02 15.2 0.1 0.07 13.5 0.1 1.9 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) TGT PF01702.18 RJW70092.1 - 3.1e-44 151.5 0.0 4.2e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase BAF250_C PF12031.8 RJW70093.1 - 1.7e-82 276.6 0.0 2.6e-82 276.0 0.0 1.3 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 RJW70093.1 - 3e-12 47.0 0.0 6.2e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DEC-1_N PF04625.13 RJW70096.1 - 3 6.7 14.2 4.6 6.1 14.2 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RVT_1 PF00078.27 RJW70097.1 - 4.1e-06 26.5 0.0 4.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0029 PF01205.19 RJW70098.1 - 1.4e-33 115.4 0.0 4.2e-33 113.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 RJW70098.1 - 2.7e-12 47.0 0.0 4.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 RWD domain tRNA_U5-meth_tr PF05958.11 RJW70099.1 - 2.6e-14 53.0 0.1 8.5e-14 51.3 0.1 1.8 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 RJW70099.1 - 1.3e-08 35.4 0.1 3.8e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW70099.1 - 9.1e-08 32.0 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 RJW70099.1 - 5.7e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 RJW70099.1 - 5e-05 22.9 0.1 8.7e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 RJW70099.1 - 0.00012 21.6 0.0 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 RJW70099.1 - 0.00023 21.7 0.1 0.00078 20.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RJW70099.1 - 0.00053 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 RJW70099.1 - 0.00061 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 RJW70099.1 - 0.0013 19.5 0.0 0.018 15.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 RJW70099.1 - 0.0024 17.7 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RJW70099.1 - 0.0034 17.2 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 RJW70099.1 - 0.0059 16.0 0.2 0.0098 15.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 RJW70099.1 - 0.088 12.7 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 RJW70099.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Tetraspanin PF00335.20 RJW70100.1 - 3.8e-14 53.0 6.9 5.6e-14 52.4 6.9 1.2 1 0 0 1 1 1 1 Tetraspanin family Pox_A14 PF05767.12 RJW70100.1 - 0.0011 19.1 1.6 0.0031 17.6 1.6 1.8 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 efThoc1 PF11957.8 RJW70103.1 - 1.8e-94 317.2 15.2 2.8e-62 211.0 9.4 2.9 2 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor RVT_1 PF00078.27 RJW70103.1 - 3.1e-45 154.4 0.0 6.6e-45 153.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.22 RJW70104.1 - 4.1e-53 179.3 1.3 1.2e-26 93.2 0.1 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 RJW70104.1 - 5.2e-29 100.9 1.2 2.4e-20 72.9 0.1 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW70104.1 - 3.9e-09 36.2 1.8 1.2e-07 31.4 1.8 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW70104.1 - 0.00041 19.8 0.1 0.00076 18.9 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RJW70104.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RJW70104.1 - 0.0061 17.0 0.2 0.15 12.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 RJW70104.1 - 0.05 13.5 0.2 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 RJW70104.1 - 0.11 12.3 0.1 0.31 10.8 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RJW70104.1 - 0.17 12.2 0.1 0.72 10.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain Vps16_N PF04841.13 RJW70105.1 - 3.7e-59 200.5 0.0 7.5e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 RJW70105.1 - 6.8e-53 179.8 0.8 9.4e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region RVT_1 PF00078.27 RJW70105.1 - 5.9e-42 143.7 0.0 9.7e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 RJW70106.1 - 1.4e-67 224.1 5.8 1e-12 48.3 0.0 11.4 8 4 1 9 9 9 9 Cadherin domain Cadherin_2 PF08266.12 RJW70106.1 - 3.9e-10 39.4 0.7 0.00038 20.2 0.2 4.6 4 0 0 4 4 4 2 Cadherin-like RET_CLD1 PF17756.1 RJW70106.1 - 0.00041 20.6 0.0 0.72 10.2 0.0 4.4 4 0 0 4 4 4 1 RET Cadherin like domain 1 Mrx7 PF10906.8 RJW70106.1 - 0.11 12.7 0.1 0.56 10.5 0.1 2.2 1 0 0 1 1 1 0 MIOREX complex component 7 Sas6_CC PF18594.1 RJW70107.1 - 0.1 12.4 2.9 0.25 11.2 2.9 1.7 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain SpoU_methylase PF00588.19 RJW70108.1 - 2e-13 50.7 0.0 3.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 RJW70108.1 - 0.0038 17.5 0.0 0.03 14.6 0.0 2.5 3 0 0 3 3 3 1 RNA 2'-O ribose methyltransferase substrate binding VHP PF02209.19 RJW70109.1 - 6.5e-16 58.1 0.6 6.5e-16 58.1 0.6 1.9 2 0 0 2 2 2 1 Villin headpiece domain LIM PF00412.22 RJW70109.1 - 3.6e-12 46.3 12.6 4.3e-07 30.1 4.7 2.4 2 0 0 2 2 2 2 LIM domain C1_1 PF00130.22 RJW70109.1 - 0.091 12.7 2.9 0.2 11.6 2.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) G_path_suppress PF15991.5 RJW70110.1 - 1.5e-14 54.8 1.2 1.5e-14 54.8 1.2 2.6 2 1 1 3 3 3 1 G-protein pathway suppressor Peptidase_M3 PF01432.20 RJW70111.1 - 1.8e-123 413.2 0.0 2.1e-123 413.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 TMEM190 PF15431.6 RJW70112.1 - 0.066 13.4 0.8 0.42 10.8 0.2 1.9 1 1 1 2 2 2 0 Transmembrane protein 190 Dpy19 PF10034.9 RJW70113.1 - 4e-178 593.6 16.8 6.8e-178 592.9 16.8 1.3 1 1 0 1 1 1 1 Q-cell neuroblast polarisation PapD-like PF14874.6 RJW70114.1 - 9.6e-06 25.7 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like ASC PF00858.24 RJW70115.1 - 7.7e-57 193.2 8.0 9.4e-57 192.9 8.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel AraC_binding_2 PF14525.6 RJW70116.1 - 0.051 13.3 0.1 0.062 13.0 0.1 1.1 1 0 0 1 1 1 0 AraC-binding-like domain DUF4537 PF15057.6 RJW70117.1 - 5e-11 42.7 0.0 9.3e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) GDP_Man_Dehyd PF16363.5 RJW70118.1 - 2.4e-55 188.3 0.0 3.2e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RJW70118.1 - 1.8e-54 184.7 0.0 2.4e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RJW70118.1 - 4.8e-17 62.0 0.0 8e-16 58.0 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RJW70118.1 - 5.2e-14 51.9 0.1 2.6e-12 46.3 0.1 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 RJW70118.1 - 5.7e-09 35.5 0.0 8.4e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 RJW70118.1 - 5.2e-08 32.4 0.0 4.4e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 RJW70118.1 - 8.4e-05 22.1 0.0 0.00022 20.8 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 RJW70118.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 RJW70118.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 RJW70118.1 - 0.0048 16.5 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family Rad1 PF02144.16 RJW70121.1 - 2.2e-48 164.7 0.1 3.5e-48 164.0 0.1 1.3 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Osteopontin PF00865.18 RJW70122.1 - 0.58 9.6 12.7 0.7 9.3 12.7 1.2 1 0 0 1 1 1 0 Osteopontin ADH_zinc_N PF00107.26 RJW70123.1 - 8.4e-16 58.1 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RJW70123.1 - 3.3e-08 33.4 0.0 5.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 RJW70123.1 - 0.00015 22.8 0.0 0.00042 21.4 0.0 1.7 1 1 0 2 2 2 1 Zinc-binding dehydrogenase TPR_11 PF13414.6 RJW70124.1 - 8.9e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.6 RJW70124.1 - 0.004 17.4 0.0 0.0056 17.0 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW70124.1 - 0.028 14.5 0.0 1 9.7 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW70124.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 RJW70127.1 - 6.7e-13 49.1 0.0 1.5e-12 48.0 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RJW70127.1 - 2.8e-12 46.8 0.0 3.5e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW70127.1 - 2.2e-10 41.1 0.0 3.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RJW70127.1 - 9.7e-10 39.1 0.0 2.3e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW70127.1 - 1.2e-06 28.4 0.0 3.1e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 RJW70127.1 - 0.00058 19.9 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RJW70127.1 - 0.0022 17.4 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 RJW70127.1 - 0.0039 16.5 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 RJW70127.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NodS PF05401.11 RJW70127.1 - 0.028 14.1 0.0 0.055 13.1 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) TehB PF03848.14 RJW70127.1 - 0.074 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Peptidase_C1 PF00112.23 RJW70129.1 - 6.6e-57 193.1 0.0 1.2e-56 192.2 0.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 RJW70129.1 - 3.5e-23 82.2 0.5 6.4e-23 81.3 0.5 1.5 1 0 0 1 1 1 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 RJW70129.1 - 0.00018 20.4 0.0 0.0016 17.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase C1-like family Propeptide_C1 PF08127.13 RJW70129.1 - 0.0007 19.4 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C1 propeptide CfAFP PF05264.11 RJW70129.1 - 0.35 10.8 3.6 0.49 10.4 0.4 2.3 2 0 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Keratin_assoc PF09775.9 RJW70131.1 - 4.1e-16 58.8 4.2 5.9e-16 58.3 4.2 1.3 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 RseC_MucC PF04246.12 RJW70131.1 - 0.99 9.4 4.4 0.36 10.8 1.1 1.8 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PsbM PF05151.12 RJW70131.1 - 4.2 7.2 8.5 0.85 9.5 1.4 2.9 3 0 0 3 3 3 0 Photosystem II reaction centre M protein (PsbM) DUF4201 PF13870.6 RJW70132.1 - 0.0018 18.0 0.5 0.0018 18.0 0.5 6.6 6 1 0 6 6 6 2 Domain of unknown function (DUF4201) ATG16 PF08614.11 RJW70132.1 - 0.0035 17.6 14.0 0.0035 17.6 14.0 6.4 4 1 2 6 6 6 1 Autophagy protein 16 (ATG16) Fez1 PF06818.15 RJW70132.1 - 9.9 6.6 66.6 0.4 11.1 11.4 4.8 3 2 1 4 4 4 0 Fez1 RT_RNaseH_2 PF17919.1 RJW70134.1 - 4e-23 81.4 0.0 8.9e-23 80.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW70134.1 - 1.5e-20 73.4 0.0 4.5e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW70134.1 - 2.8e-16 59.7 0.0 5.6e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 RJW70134.1 - 0.034 14.5 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF3081 PF11280.8 RJW70134.1 - 0.13 12.1 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) HMA PF00403.26 RJW70136.1 - 0.00061 20.2 0.3 0.0015 18.9 0.1 1.8 2 0 0 2 2 2 1 Heavy-metal-associated domain Sad1_UNC PF07738.13 RJW70136.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Ank_2 PF12796.7 RJW70137.1 - 1.7e-09 38.1 2.1 0.00052 20.6 1.9 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW70137.1 - 7.8e-08 32.0 10.6 0.29 11.8 0.6 6.0 6 1 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 RJW70137.1 - 1.4e-07 31.9 8.1 0.0044 17.6 0.3 5.4 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW70137.1 - 0.00017 21.8 2.6 0.38 11.1 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RJW70137.1 - 0.091 13.3 12.1 10 6.8 0.6 4.8 4 1 0 4 4 4 0 Ankyrin repeat RelB_transactiv PF16181.5 RJW70139.1 - 0.063 13.5 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 RelB transactivation domain RVT_1 PF00078.27 RJW70140.1 - 4.3e-41 140.9 0.0 1.1e-40 139.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 RJW70140.1 - 2.8e-09 36.6 0.0 4.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exo_endo_phos_2 PF14529.6 RJW70140.1 - 8.2e-07 28.9 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase 2Fe-2S_thioredx PF01257.19 RJW70141.1 - 1e-60 203.8 0.0 1.3e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Pkinase PF00069.25 RJW70143.1 - 3.9e-28 98.5 0.0 1.8e-27 96.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW70143.1 - 2.2e-25 89.5 0.0 8e-21 74.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 RJW70143.1 - 2.3e-20 72.1 27.6 0.00012 21.7 1.1 8.0 7 0 0 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 RJW70143.1 - 2.5e-18 65.9 27.1 1e-05 25.8 0.2 8.9 7 1 1 8 8 8 4 Leucine Rich repeats (2 copies) Ank_3 PF13606.6 RJW70143.1 - 1.2e-07 31.5 0.2 0.25 12.0 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeat COR PF16095.5 RJW70143.1 - 1.5e-07 31.4 0.0 1.6e-05 24.8 0.0 3.1 3 0 0 3 3 3 1 C-terminal of Roc, COR, domain Ank_2 PF12796.7 RJW70143.1 - 4.1e-07 30.5 0.0 0.2 12.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW70143.1 - 8.9e-07 29.1 0.4 0.079 13.3 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW70143.1 - 2.2e-05 24.9 0.6 1.3 9.7 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Roc PF08477.13 RJW70143.1 - 5.7e-05 23.3 0.3 0.08 13.2 0.0 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Ank PF00023.30 RJW70143.1 - 0.00013 22.3 0.9 0.96 10.0 0.0 4.0 3 0 0 3 3 2 2 Ankyrin repeat LRR_6 PF13516.6 RJW70143.1 - 0.0052 16.7 19.6 0.59 10.3 0.1 7.6 7 0 0 7 7 7 2 Leucine Rich repeat AAA_16 PF13191.6 RJW70143.1 - 0.0054 17.1 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 RJW70143.1 - 0.0057 16.3 0.0 0.071 12.7 0.0 2.1 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.27 RJW70143.1 - 0.025 15.1 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter LRR_1 PF00560.33 RJW70143.1 - 0.33 11.7 38.1 0.49 11.1 0.2 10.5 11 1 0 11 11 9 0 Leucine Rich Repeat Kelch_1 PF01344.25 RJW70144.1 - 1.2e-62 207.3 10.8 1.5e-14 53.3 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RJW70144.1 - 4.9e-43 144.1 8.4 9.8e-09 35.2 0.1 7.1 4 2 3 7 7 7 5 Kelch motif Kelch_2 PF07646.15 RJW70144.1 - 2.2e-31 106.7 7.9 7.9e-07 28.8 0.0 7.2 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 RJW70144.1 - 2.3e-24 85.1 3.2 0.0001 22.2 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 RJW70144.1 - 1.4e-23 83.2 0.0 6.1e-22 78.0 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 RJW70144.1 - 3.2e-17 62.4 3.8 0.0012 19.0 0.0 6.6 6 0 0 6 6 6 4 Galactose oxidase, central domain BACK PF07707.15 RJW70144.1 - 2.4e-15 56.5 0.1 4.3e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 RJW70144.1 - 3.1e-08 33.4 5.8 0.18 11.8 0.0 5.1 5 0 0 5 5 5 3 Kelch motif DUF3342 PF11822.8 RJW70144.1 - 0.026 14.7 0.0 1.3 9.3 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3342) Varsurf_PPLC PF03490.13 RJW70144.1 - 0.083 12.8 0.4 1.8 8.6 0.0 3.2 4 0 0 4 4 4 0 Variant-surface-glycoprotein phospholipase C Kelch_6 PF13964.6 RJW70145.1 - 1.2e-11 44.5 6.4 0.063 13.6 0.2 7.1 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 RJW70145.1 - 1.9e-11 43.7 8.1 0.13 12.2 0.2 6.0 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 RJW70145.1 - 3e-09 36.7 1.5 0.6 10.2 0.0 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 RJW70145.1 - 2.5e-07 30.4 3.9 0.4 10.7 0.0 5.4 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 RJW70145.1 - 3.3e-07 30.4 11.8 0.35 11.2 0.7 7.1 6 1 0 6 6 6 2 Galactose oxidase, central domain RVT_1 PF00078.27 RJW70145.1 - 6e-07 29.2 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_1 PF01344.25 RJW70145.1 - 8.2e-05 22.1 2.0 3.8 7.2 0.4 4.9 5 0 0 5 5 5 2 Kelch motif Ank_2 PF12796.7 RJW70147.1 - 1.3e-37 128.3 0.1 5e-13 49.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW70147.1 - 1.7e-34 117.7 2.4 4.3e-11 43.1 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW70147.1 - 1.4e-33 114.5 1.9 1.3e-07 31.8 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW70147.1 - 3.2e-31 103.9 0.1 3.2e-05 24.0 0.0 5.6 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 RJW70147.1 - 1.8e-28 97.7 1.0 3.6e-05 24.0 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat ScdA_N PF04405.14 RJW70147.1 - 0.12 12.0 0.1 13 5.5 0.0 3.3 4 0 0 4 4 4 0 Domain of Unknown function (DUF542) WD40 PF00400.32 RJW70149.1 - 4.4e-71 233.0 21.3 7.6e-10 39.2 0.1 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW70149.1 - 3.6e-25 88.1 0.5 0.00034 20.8 0.0 6.0 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW70149.1 - 3.3e-11 42.5 11.6 0.14 10.7 0.0 6.5 2 2 5 7 7 7 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RJW70149.1 - 1.2e-09 37.4 0.1 0.017 13.9 0.0 4.2 2 1 3 5 5 5 3 Nup133 N terminal like Ge1_WD40 PF16529.5 RJW70149.1 - 0.0012 17.8 7.3 0.14 11.1 0.6 4.0 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 RJW70149.1 - 0.064 11.6 0.0 2.2 6.5 0.0 2.4 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz RhlB PF12300.8 RJW70149.1 - 1 9.5 5.3 0.15 12.2 0.8 1.8 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Thiolase_N PF00108.23 RJW70150.1 - 4.1e-73 245.9 0.0 6.4e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RJW70150.1 - 3.3e-43 146.3 0.1 6e-43 145.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Exo_endo_phos PF03372.23 RJW70152.1 - 1.8e-08 34.2 0.0 3.6e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LicD PF04991.13 RJW70154.1 - 6.6e-10 39.5 3.5 2.8e-09 37.4 3.1 1.9 1 1 1 2 2 2 1 LicD family GCP_C_terminal PF04130.13 RJW70155.1 - 3.1e-43 148.4 6.0 3.1e-43 148.4 6.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 RJW70155.1 - 0.0028 17.4 0.0 0.014 15.0 0.0 2.1 1 1 1 2 2 2 1 Gamma tubulin complex component N-terminal FapA PF03961.13 RJW70155.1 - 0.6 8.6 2.5 0.84 8.2 2.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2863 PF11062.8 RJW70156.1 - 0.09 11.2 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Erf4 PF10256.9 RJW70157.1 - 6e-20 71.5 0.0 8.7e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family UPF0047 PF01894.17 RJW70159.1 - 2.1e-33 114.9 0.0 3.6e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Chromo_2 PF18704.1 RJW70159.1 - 3.2e-22 78.6 0.1 7.6e-22 77.4 0.1 1.7 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 XPG_I PF00867.18 RJW70159.1 - 1.2e-20 73.6 0.0 2.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region RVT_1 PF00078.27 RJW70159.1 - 2e-06 27.5 0.0 4.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DM PF00751.18 RJW70159.1 - 2.4 8.1 5.0 9.7 6.2 1.5 2.7 2 0 0 2 2 2 0 DM DNA binding domain Hjc PF01870.18 RJW70160.1 - 0.03 14.3 0.1 0.059 13.4 0.1 1.4 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) DnaJ PF00226.31 RJW70162.1 - 9.2e-26 89.8 0.4 1.5e-25 89.1 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain YfhO PF09586.10 RJW70162.1 - 9.5 4.3 5.5 0.9 7.7 0.9 1.5 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Topoisom_bac PF01131.20 RJW70163.1 - 6.6e-109 364.6 0.0 8e-109 364.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 RJW70163.1 - 6.3e-18 64.9 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Toprim domain zinc_ribbon_5 PF13719.6 RJW70163.1 - 0.11 12.3 7.0 2.1 8.2 0.3 4.4 4 0 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.13 RJW70163.1 - 6.9 6.8 10.2 0.85 9.7 0.2 3.4 3 1 0 3 3 3 0 Transcription elongation factor Elf1 like UQ_con PF00179.26 RJW70164.1 - 6.7e-49 165.2 0.0 9.3e-49 164.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chromo_2 PF18704.1 RJW70165.1 - 0.032 14.5 0.4 0.06 13.6 0.4 1.4 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 Frizzled PF01534.17 RJW70167.1 - 6.6e-22 78.0 17.2 6.6e-17 61.5 3.1 3.6 3 1 0 4 4 4 2 Frizzled/Smoothened family membrane region Fz PF01392.22 RJW70167.1 - 4.2e-08 33.8 0.0 4e-07 30.7 0.0 2.8 1 1 0 1 1 1 1 Fz domain Mid1 PF12929.7 RJW70167.1 - 0.0036 16.6 0.1 0.0062 15.8 0.1 1.3 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Ras PF00071.22 RJW70168.1 - 6.5e-21 74.6 0.0 1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Ras family DnaJ PF00226.31 RJW70168.1 - 6.6e-16 58.2 0.0 1.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Roc PF08477.13 RJW70168.1 - 7e-07 29.5 0.9 3.2e-06 27.3 0.0 2.3 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW70168.1 - 0.0003 20.3 0.0 0.0006 19.3 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF2277 PF10041.9 RJW70168.1 - 0.0028 18.0 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2277) Presenilin PF01080.17 RJW70168.1 - 7.9 5.1 5.1 10 4.8 5.1 1.1 1 0 0 1 1 1 0 Presenilin ORMDL PF04061.14 RJW70169.1 - 2.6e-34 117.9 0.0 3e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 ORMDL family TIR_2 PF13676.6 RJW70170.1 - 1.3e-12 48.4 0.0 5.4e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 TIR domain SAM_1 PF00536.30 RJW70170.1 - 0.0034 17.8 0.0 0.0093 16.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 RJW70170.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RJW70170.1 - 0.047 13.8 0.0 0.18 11.9 0.0 2.0 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1127 PF06568.11 RJW70170.1 - 0.61 9.9 3.6 0.42 10.4 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) JmjC PF02373.22 RJW70171.1 - 4.7e-43 146.2 0.9 1e-42 145.1 0.3 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.29 RJW70171.1 - 2.9e-21 75.1 20.0 1e-10 41.3 5.0 3.1 2 0 0 2 2 2 2 PHD-finger PLU-1 PF08429.11 RJW70171.1 - 1.4e-16 60.7 0.1 1.5e-14 53.9 0.0 3.8 3 1 0 3 3 3 1 PLU-1-like protein zf-C5HC2 PF02928.16 RJW70171.1 - 3.5e-12 46.5 10.3 3.5e-12 46.5 10.3 2.6 2 0 0 2 2 2 1 C5HC2 zinc finger ARID PF01388.21 RJW70171.1 - 8.1e-11 42.5 0.0 2.5e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Aldo_ket_red PF00248.21 RJW70174.1 - 4.4e-47 160.7 0.0 1.7e-46 158.8 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Antibiotic_NAT PF02522.14 RJW70174.1 - 0.093 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase HSP70 PF00012.20 RJW70175.1 - 3.6e-33 114.6 0.0 4.7e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein 7tm_1 PF00001.21 RJW70176.1 - 4.1e-47 160.7 21.1 2.6e-27 95.8 7.4 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW70176.1 - 9e-10 38.4 17.1 8.6e-07 28.6 8.0 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RJW70176.1 - 0.005 16.6 6.0 0.005 16.6 6.0 2.1 2 0 0 2 2 2 2 Olfactory receptor Fasciclin PF02469.22 RJW70177.1 - 1.5e-22 80.2 0.0 5.4e-14 52.5 0.0 3.3 3 0 0 3 3 3 3 Fasciclin domain CarboxypepD_reg PF13620.6 RJW70179.1 - 1.7e-05 25.0 0.0 4.4e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 RJW70179.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 CarboxypepD_reg-like domain DHHC PF01529.20 RJW70184.1 - 3.4e-21 75.8 15.9 3.4e-21 75.8 15.9 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 RJW70184.1 - 3.2e-14 53.1 1.0 5.5e-08 33.2 0.4 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW70184.1 - 2.7e-13 50.3 0.8 6e-12 46.0 0.4 2.7 2 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 RJW70184.1 - 7.5e-13 48.3 4.2 4.6e-07 30.0 0.4 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RJW70184.1 - 3.7e-12 45.3 0.3 0.00017 21.7 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RJW70184.1 - 1.1e-11 44.7 1.6 1.2e-05 25.4 0.9 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DctQ PF04290.12 RJW70184.1 - 0.0089 16.0 0.6 0.0089 16.0 0.6 2.4 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component 7tm_1 PF00001.21 RJW70185.1 - 5.3e-06 26.0 23.5 7.2e-06 25.5 23.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF5392 PF17370.2 RJW70185.1 - 0.049 13.7 1.6 0.17 11.9 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5392) HSP70 PF00012.20 RJW70186.1 - 1.2e-21 76.6 3.7 2.1e-21 75.8 3.6 1.4 1 1 0 1 1 1 1 Hsp70 protein PIN_5 PF08745.11 RJW70186.1 - 0.074 12.5 0.5 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 PINc domain ribonuclease vATP-synt_E PF01991.18 RJW70186.1 - 0.32 10.4 3.9 0.68 9.3 0.6 2.3 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Ank_2 PF12796.7 RJW70188.1 - 1.6e-32 111.9 2.0 1.8e-16 60.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RJW70188.1 - 1.4e-31 107.5 4.6 9.4e-06 25.9 0.0 6.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 RJW70188.1 - 1.5e-26 92.4 1.1 1.6e-07 31.7 0.2 5.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW70188.1 - 2.3e-25 88.3 5.0 5.3e-07 29.8 0.0 4.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW70188.1 - 1.1e-23 80.7 6.6 1.1e-05 25.4 0.2 6.6 7 0 0 7 7 7 4 Ankyrin repeat Spectrin PF00435.21 RJW70189.1 - 2.2e-36 124.5 185.3 8e-10 39.1 3.7 27.5 25 5 0 26 26 25 11 Spectrin repeat GAS2 PF02187.17 RJW70189.1 - 8.5e-30 102.7 0.4 8.5e-30 102.7 0.4 2.2 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_1 PF00036.32 RJW70189.1 - 5.8e-08 31.7 0.3 0.0024 17.3 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW70189.1 - 2e-07 30.4 0.5 0.0037 17.1 0.0 3.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RJW70189.1 - 6.4e-07 29.7 2.8 2.7e-06 27.7 0.5 3.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW70189.1 - 0.00049 19.9 0.3 3.7 7.5 0.0 3.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW70189.1 - 0.00064 19.1 1.2 0.71 9.5 0.1 3.0 2 0 0 2 2 2 2 EF hand Corona_5a PF06336.11 RJW70189.1 - 0.13 12.3 0.2 0.39 10.7 0.2 1.9 1 0 0 1 1 1 0 Coronavirus 5a protein Bcr-Abl_Oligo PF09036.10 RJW70189.1 - 0.14 12.1 0.8 3 7.9 0.1 3.8 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Par3_HAL_N_term PF12053.8 RJW70189.1 - 0.55 10.5 2.7 3.1 8.1 0.2 3.4 3 0 0 3 3 3 0 N-terminal of Par3 and HAL proteins Complex1_LYR_2 PF13233.6 RJW70189.1 - 5.5 7.8 8.5 2.1 9.1 0.3 4.8 3 1 0 3 3 2 0 Complex1_LYR-like MENTAL PF10457.9 RJW70191.1 - 6.8e-53 179.1 1.5 1.4e-52 178.1 1.5 1.5 1 0 0 1 1 1 1 Cholesterol-capturing domain START PF01852.19 RJW70191.1 - 1.1e-19 70.7 0.0 2.2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 START domain CAP PF00188.26 RJW70192.1 - 1.5e-07 32.3 0.1 2e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family T2SSE PF00437.20 RJW70193.1 - 0.18 10.8 0.0 0.21 10.6 0.0 1.0 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_6 PF12774.7 RJW70194.1 - 1.5e-155 517.2 0.0 2.8e-153 509.7 0.0 3.3 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region MT PF12777.7 RJW70194.1 - 2e-137 457.9 8.8 3.8e-137 456.9 8.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DHC_N2 PF08393.13 RJW70194.1 - 1.1e-107 360.6 15.3 1.1e-107 360.6 15.3 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RJW70194.1 - 1.1e-93 313.3 0.0 8.1e-93 310.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RJW70194.1 - 3.1e-93 312.4 0.0 2.4e-92 309.4 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RJW70194.1 - 2.1e-82 275.5 0.9 2.1e-82 275.5 0.9 2.6 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 RJW70194.1 - 3.4e-75 251.5 0.1 5.6e-68 228.0 0.0 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RJW70194.1 - 4.9e-52 176.1 0.0 1.2e-51 174.8 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RJW70194.1 - 1.5e-38 131.6 0.0 3.5e-37 127.1 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 RJW70194.1 - 1e-30 105.9 2.4 3.2e-30 104.3 0.2 3.0 2 0 0 2 2 2 1 AAA+ lid domain DHC_N1 PF08385.12 RJW70194.1 - 1.7e-28 99.7 0.1 1.7e-28 99.7 0.1 3.4 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 RJW70194.1 - 3.6e-27 95.0 0.0 6.5e-12 45.6 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RJW70194.1 - 1.2e-24 86.9 1.6 1.2e-24 86.9 1.6 2.9 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 RJW70194.1 - 1.6e-07 31.9 0.4 0.33 11.3 0.0 6.2 5 1 1 6 6 6 2 AAA ATPase domain AAA_22 PF13401.6 RJW70194.1 - 1.1e-06 29.0 0.0 1.4 9.1 0.0 5.9 5 0 0 5 5 3 1 AAA domain AAA_30 PF13604.6 RJW70194.1 - 4.9e-05 23.1 0.7 0.8 9.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 RJW70194.1 - 0.00011 22.7 0.1 0.48 11.0 0.0 4.9 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 RJW70194.1 - 0.00018 21.2 0.0 0.044 13.5 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 RJW70194.1 - 0.00062 20.2 0.1 0.64 10.4 0.0 4.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 RJW70194.1 - 0.0017 18.4 0.1 33 4.5 0.0 4.8 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 RJW70194.1 - 0.0034 17.7 0.1 18 5.8 0.0 3.8 3 0 0 3 3 3 0 RNA helicase DUF2075 PF09848.9 RJW70194.1 - 0.004 16.5 0.1 1.1 8.4 0.0 3.1 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) LcrV PF04792.12 RJW70194.1 - 0.0087 15.4 0.4 0.024 14.0 0.4 1.7 1 0 0 1 1 1 1 V antigen (LcrV) protein Mg_chelatase PF01078.21 RJW70194.1 - 0.014 14.8 0.1 4.4 6.6 0.0 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 RJW70194.1 - 0.02 14.1 0.0 0.083 12.0 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase AAA_19 PF13245.6 RJW70194.1 - 0.029 14.7 2.0 19 5.6 0.0 4.2 4 0 0 4 4 3 0 AAA domain Retrotran_gag_2 PF14223.6 RJW70194.1 - 0.03 14.0 0.7 0.24 11.1 0.1 2.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type ATP_bind_1 PF03029.17 RJW70194.1 - 0.04 13.7 1.5 0.33 10.7 0.0 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 RJW70194.1 - 0.043 12.7 2.3 0.4 9.5 0.0 3.1 4 0 0 4 4 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 RJW70194.1 - 0.044 13.0 0.2 11 5.1 0.0 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 RJW70194.1 - 0.053 13.6 0.0 19 5.4 0.0 3.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.6 RJW70194.1 - 0.057 13.2 0.2 43 4.0 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_24 PF13479.6 RJW70194.1 - 0.069 12.9 2.3 2.8 7.6 0.0 4.0 4 0 0 4 4 4 0 AAA domain MSV199 PF10553.9 RJW70194.1 - 0.091 13.0 0.0 0.36 11.1 0.0 2.0 1 0 0 1 1 1 0 MSV199 domain AAA_25 PF13481.6 RJW70194.1 - 0.12 11.9 0.2 0.74 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RJW70194.1 - 0.12 12.6 0.3 1.8e+02 2.3 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 RJW70194.1 - 0.15 12.2 0.7 1e+02 3.0 0.0 4.2 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.27 RJW70194.1 - 0.44 11.1 7.7 15 6.1 0.0 4.7 5 0 0 5 5 2 0 ABC transporter PHM7_cyt PF14703.6 RJW70194.1 - 2.1 8.6 6.4 2.4 8.4 0.4 3.7 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4816 PF16086.5 RJW70195.1 - 0.037 14.0 9.0 55 3.8 9.0 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) Peptidase_M14 PF00246.24 RJW70197.1 - 5.8e-36 124.8 0.3 6e-34 118.2 0.2 2.2 2 0 0 2 2 2 2 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 RJW70197.1 - 5.2e-06 26.6 0.0 9.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Beach PF02138.18 RJW70198.1 - 9.9e-119 395.8 0.0 1.8e-118 394.9 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 RJW70198.1 - 4.8e-15 55.5 0.0 1.9e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 RJW70198.1 - 5.5e-15 55.3 0.9 1.5e-08 34.2 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4800) WD40 PF00400.32 RJW70198.1 - 0.61 11.1 2.4 21 6.2 0.1 4.2 3 0 0 3 3 3 0 WD domain, G-beta repeat RBM39linker PF15519.6 RJW70200.1 - 0.21 12.7 1.7 0.5 11.5 1.7 1.6 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein RepB PF07506.11 RJW70201.1 - 0.061 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein SIR2 PF02146.17 RJW70203.1 - 2.2e-60 203.6 0.0 4.8e-60 202.5 0.0 1.6 2 0 0 2 2 2 1 Sir2 family TPP_enzyme_M PF00205.22 RJW70203.1 - 5.7e-05 22.9 0.0 0.0034 17.1 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 RJW70203.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Myc_N PF01056.18 RJW70203.1 - 0.19 11.6 5.0 5.1 6.9 1.2 2.1 2 0 0 2 2 2 0 Myc amino-terminal region TBP PF00352.21 RJW70204.1 - 3.6e-68 225.5 0.6 4.4e-33 113.1 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 RJW70204.1 - 9.2e-05 22.5 0.3 0.56 10.4 0.0 3.0 4 0 0 4 4 4 2 Domain of unknown function (DUF3378) Baculo_PEP_C PF04513.12 RJW70206.1 - 0.00024 21.2 0.7 0.00029 20.9 0.7 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF842 PF05811.13 RJW70206.1 - 0.065 12.9 0.2 0.51 10.0 0.1 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Ferritin PF00210.24 RJW70207.1 - 7.5e-19 68.1 0.0 8.7e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain Ndr PF03096.14 RJW70208.1 - 0.045 12.5 0.1 0.06 12.1 0.1 1.1 1 0 0 1 1 1 0 Ndr family RVT_1 PF00078.27 RJW70209.1 - 0.0082 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1664 PF07889.12 RJW70211.1 - 0.0099 15.9 0.5 0.012 15.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 RJW70211.1 - 0.011 15.8 1.3 0.018 15.2 1.3 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 RJW70211.1 - 0.036 14.1 1.9 0.04 14.0 1.9 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 RJW70211.1 - 0.098 12.6 0.2 0.13 12.2 0.2 1.4 1 1 0 1 1 1 0 Apolipoprotein O Mad3_BUB1_I PF08311.12 RJW70212.1 - 5.8e-32 110.3 0.0 7.4e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 RJW70212.1 - 0.042 14.0 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein P16-Arc PF04699.14 RJW70214.1 - 2e-45 154.9 0.6 2.3e-45 154.7 0.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DnaB_2 PF07261.11 RJW70214.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Replication initiation and membrane attachment Utp12 PF04003.12 RJW70214.1 - 0.031 14.6 0.0 0.081 13.2 0.0 1.6 1 1 1 2 2 2 0 Dip2/Utp12 Family Utp13 PF08625.11 RJW70214.1 - 0.082 12.8 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain PH PF00169.29 RJW70215.1 - 3.9e-21 75.5 0.2 5.7e-11 42.9 0.1 2.6 2 0 0 2 2 2 2 PH domain RhoGEF PF00621.20 RJW70215.1 - 1.5e-20 74.3 0.0 2.4e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Helicase_C_2 PF13307.6 RJW70215.1 - 0.03 14.5 0.2 0.27 11.4 0.2 2.3 1 1 0 1 1 1 0 Helicase C-terminal domain PH_8 PF15409.6 RJW70215.1 - 0.033 14.5 0.1 0.49 10.7 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 RJW70215.1 - 0.16 11.8 0.0 3.6 7.4 0.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 RJW70215.1 - 0.69 10.4 3.8 5.6 7.4 1.4 3.4 3 1 0 3 3 3 0 Pleckstrin homology domain FBA_2 PF07735.17 RJW70216.1 - 0.038 14.1 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 F-box associated Zn-ribbon_8 PF09723.10 RJW70216.1 - 0.066 13.3 9.4 34 4.7 0.0 4.5 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 RJW70216.1 - 0.2 12.4 14.0 0.39 11.5 0.8 3.9 1 1 3 4 4 4 0 zinc-ribbon family Lar_restr_allev PF14354.6 RJW70216.1 - 0.72 10.3 8.5 7.6 7.0 0.0 3.7 3 1 1 4 4 4 0 Restriction alleviation protein Lar PhnA_Zn_Ribbon PF08274.12 RJW70216.1 - 1.1 9.3 8.0 5.1 7.1 0.1 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-DBF PF07535.12 RJW70216.1 - 1.8 8.7 8.3 16 5.7 0.1 3.6 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2_4 PF13894.6 RJW70216.1 - 2 9.5 24.5 0.46 11.5 0.4 5.7 5 0 0 5 5 5 0 C2H2-type zinc finger DUF4451 PF14616.6 RJW70216.1 - 3.8 7.7 12.4 3.3 7.9 0.7 3.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4451) DZR PF12773.7 RJW70216.1 - 7.2 6.7 15.9 17 5.6 0.6 4.5 2 1 0 2 2 2 0 Double zinc ribbon G-patch PF01585.23 RJW70217.1 - 1e-05 25.3 0.6 2.2e-05 24.3 0.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RJW70217.1 - 0.0066 16.5 0.2 0.018 15.1 0.2 1.7 1 0 0 1 1 1 1 G-patch domain GDPD PF03009.17 RJW70218.1 - 4.4e-20 72.5 0.0 6.6e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 RJW70218.1 - 0.003 17.1 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain ANF_receptor PF01094.28 RJW70219.1 - 4.7e-70 236.4 0.0 5.8e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RJW70219.1 - 2.1e-07 31.0 0.1 4.1e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Ribosomal_S10 PF00338.22 RJW70220.1 - 0.0001 22.5 0.2 0.00047 20.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e RT_RNaseH_2 PF17919.1 RJW70221.1 - 3.9e-17 62.1 0.0 5.6e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW70221.1 - 5.7e-13 49.1 0.0 7.3e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase EF-hand_7 PF13499.6 RJW70222.1 - 8.5e-10 38.9 2.5 5.2e-09 36.4 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW70222.1 - 2.7e-07 30.0 1.5 0.0026 17.5 0.1 3.1 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 RJW70222.1 - 5.4e-06 25.6 0.1 0.12 12.0 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RJW70222.1 - 0.00017 21.3 0.3 0.0044 16.8 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 RJW70222.1 - 0.00033 20.0 0.0 0.0068 15.9 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 RJW70222.1 - 0.041 13.7 0.5 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 RJW70222.1 - 0.088 13.1 7.6 0.43 10.9 2.1 2.9 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SCAI PF12070.8 RJW70223.1 - 9.3e-121 404.3 0.0 1.2e-120 404.0 0.0 1.1 1 0 0 1 1 1 1 Protein SCAI PX PF00787.24 RJW70225.1 - 1e-06 28.7 0.0 3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 PX domain PLDc PF00614.22 RJW70225.1 - 4.5e-06 26.6 0.2 1.2e-05 25.3 0.2 1.8 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc_2 PF13091.6 RJW70225.1 - 0.0016 18.3 0.4 0.023 14.6 0.0 2.9 3 0 0 3 3 3 1 PLD-like domain PH PF00169.29 RJW70225.1 - 0.027 15.0 0.4 0.081 13.4 0.4 1.9 1 1 0 1 1 1 0 PH domain CHU_C PF13585.6 RJW70225.1 - 0.13 12.3 0.5 0.36 10.9 0.1 1.8 2 0 0 2 2 2 0 C-terminal domain of CHU protein family GDPD PF03009.17 RJW70226.1 - 1.3e-26 93.9 0.0 6.3e-24 85.1 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 RJW70226.1 - 0.039 14.4 0.0 0.082 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DENN PF02141.21 RJW70228.1 - 4e-29 101.9 0.4 9.7e-29 100.6 0.4 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 RJW70228.1 - 2.2e-09 37.1 0.9 7.3e-09 35.5 0.9 2.0 1 0 0 1 1 1 1 dDENN domain Avl9 PF09794.9 RJW70228.1 - 0.0073 15.0 0.5 0.019 13.6 0.5 1.6 1 0 0 1 1 1 1 Transport protein Avl9 HCMVantigenic_N PF12154.8 RJW70228.1 - 6 7.1 5.9 0.77 9.9 1.0 2.1 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV Chromo PF00385.24 RJW70229.1 - 2e-13 50.0 0.0 3.6e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ank_4 PF13637.6 RJW70229.1 - 0.028 15.0 0.0 0.2 12.3 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) FeoA PF04023.14 RJW70229.1 - 0.044 14.0 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 FeoA domain Ank_2 PF12796.7 RJW70229.1 - 0.097 13.3 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF4660 PF15559.6 RJW70230.1 - 0.075 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) zf-C2H2 PF00096.26 RJW70232.1 - 0.75 10.4 7.6 0.35 11.4 2.1 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Forkhead PF00250.18 RJW70235.1 - 5.6e-39 132.3 0.0 1.3e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain Act-Frag_cataly PF09192.10 RJW70236.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 Actin-fragmin kinase, catalytic DUF2462 PF09495.10 RJW70238.1 - 2.9 8.7 7.5 3.3 8.5 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2462) PAP2_C PF14360.6 RJW70239.1 - 2.4e-27 95.3 9.1 2.4e-27 95.3 9.1 3.1 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_2 PF07647.17 RJW70239.1 - 8.8e-07 29.0 0.1 2.2e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RJW70239.1 - 5.3e-06 26.8 0.1 9.9e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2_3 PF14378.6 RJW70239.1 - 0.00011 22.0 8.8 0.00011 22.0 8.8 1.5 1 1 0 1 1 1 1 PAP2 superfamily N1221 PF07923.13 RJW70239.1 - 0.02 14.1 0.4 0.36 10.0 0.5 2.1 2 0 0 2 2 2 0 N1221-like protein PAP2 PF01569.21 RJW70239.1 - 0.087 12.6 15.2 0.016 15.0 10.1 2.2 1 1 1 2 2 2 0 PAP2 superfamily CI-B14_5a PF07347.12 RJW70240.1 - 0.086 12.7 0.7 3.5 7.6 0.0 3.0 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) V_ATPase_I PF01496.19 RJW70243.1 - 7e-282 937.2 8.9 7.9e-282 937.0 8.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Metallophos PF00149.28 RJW70244.1 - 1e-34 120.9 0.1 1.4e-34 120.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RJW70244.1 - 0.00014 22.2 0.3 0.00029 21.2 0.3 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 RJW70244.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TFIIF_alpha PF05793.12 RJW70246.1 - 1.7e-64 218.3 54.5 8.6e-58 196.2 12.7 3.8 2 2 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) adh_short PF00106.25 RJW70246.1 - 5.9e-23 81.3 0.9 1.2e-22 80.3 0.4 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW70246.1 - 3.5e-13 49.6 0.2 4.4e-12 46.1 0.2 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RJW70246.1 - 3.3e-07 30.0 0.0 5.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 RJW70246.1 - 2.6e-06 27.4 0.1 5.6e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RJW70246.1 - 0.013 15.3 0.1 0.046 13.6 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 RJW70246.1 - 0.016 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 7tm_3 PF00003.22 RJW70247.1 - 1.7e-60 204.7 16.0 2.5e-60 204.2 16.0 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 RJW70247.1 - 1.4e-10 40.9 12.8 2.8e-10 40.0 12.8 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR PdaC PF13739.6 RJW70247.1 - 0.4 11.7 5.7 0.19 12.7 2.8 2.0 2 0 0 2 2 2 0 Deacetylase PdaC DctQ PF04290.12 RJW70247.1 - 2.1 8.3 7.4 0.49 10.3 0.3 2.7 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Septin PF00735.18 RJW70250.1 - 3.1e-83 279.3 0.2 3.9e-83 279.0 0.2 1.1 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 RJW70250.1 - 4.2e-10 39.8 0.3 1.1e-08 35.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 RJW70250.1 - 6.5e-09 35.9 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RJW70250.1 - 2.5e-05 23.7 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 RJW70250.1 - 8.2e-05 22.2 0.2 0.037 13.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 RJW70250.1 - 0.00047 20.2 0.3 0.89 9.6 0.1 2.7 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 RJW70250.1 - 0.00052 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 RJW70250.1 - 0.0051 17.3 0.0 0.0087 16.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Ras PF00071.22 RJW70250.1 - 0.0054 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 RJW70250.1 - 0.0081 16.4 0.0 0.023 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RJW70250.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 RJW70250.1 - 0.017 15.5 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 RJW70250.1 - 0.02 14.6 0.1 0.034 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RJW70250.1 - 0.021 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 RJW70250.1 - 0.078 12.3 0.3 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TGFb_propeptide PF00688.18 RJW70250.1 - 0.081 12.6 0.1 0.2 11.3 0.1 1.8 1 1 0 1 1 1 0 TGF-beta propeptide Histone_H2A_C PF16211.5 RJW70251.1 - 9.5e-17 60.4 1.3 1.9e-16 59.5 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 RJW70251.1 - 2.2e-14 53.9 0.0 3.5e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RJW70251.1 - 0.00037 20.7 0.0 0.00062 20.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CAP_GLY PF01302.25 RJW70253.1 - 4.1e-19 68.4 0.8 7.2e-19 67.6 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 RJW70253.1 - 1.1e-06 28.8 10.2 0.00019 21.8 1.2 4.5 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RJW70253.1 - 8.2e-06 25.5 1.8 2 8.7 0.4 4.1 3 0 0 3 3 3 3 Leucine Rich repeat LRR_9 PF14580.6 RJW70253.1 - 0.014 14.9 0.4 0.75 9.3 0.0 2.9 3 0 0 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.33 RJW70253.1 - 0.032 14.7 4.2 18 6.4 0.4 4.6 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 RJW70253.1 - 0.039 13.7 9.6 3.1 7.6 1.7 4.9 3 3 1 4 4 4 0 Leucine rich repeat NupH_GANP PF16768.5 RJW70254.1 - 0.04 13.6 3.1 0.053 13.2 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin homology of Germinal-centre associated nuclear protein CAP_N PF01213.19 RJW70255.1 - 1.6e-17 64.0 0.6 1.3e-07 31.5 0.1 3.1 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal TetR_C_7 PF14246.6 RJW70255.1 - 0.075 13.1 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain FERM_C PF09380.10 RJW70256.1 - 1.3e-21 76.8 0.6 2.2e-21 76.0 0.6 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RJW70256.1 - 2.4e-14 53.8 0.0 4.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 RJW70256.1 - 1.6e-11 44.1 0.5 3.8e-11 42.9 0.5 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 RJW70256.1 - 6.5e-10 38.8 0.0 1.8e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 FERM N-terminal domain ATP-gua_Ptrans PF00217.19 RJW70259.1 - 3.2e-29 102.0 0.0 1.9e-28 99.4 0.0 2.0 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 RJW70259.1 - 1.8e-06 28.3 0.0 4.8e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF5600 PF18150.1 RJW70260.1 - 4.9e-41 139.6 0.8 1.9e-40 137.8 0.3 2.2 3 0 0 3 3 2 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 RJW70260.1 - 3.4e-20 71.9 0.1 1.1e-19 70.3 0.1 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 RJW70260.1 - 2.1e-13 50.7 0.0 3e-12 46.9 0.0 2.3 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 RJW70260.1 - 4e-12 45.8 0.1 8.7e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 RJW70260.1 - 2.6e-07 30.7 0.0 6.4e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 RJW70260.1 - 0.0006 19.2 0.1 0.003 17.0 0.0 2.3 2 0 0 2 2 2 1 EF hand GTP_EFTU PF00009.27 RJW70260.1 - 0.0095 15.5 0.1 0.083 12.4 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.6 RJW70260.1 - 0.02 14.8 0.0 0.099 12.6 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 RJW70260.1 - 0.022 15.2 0.3 0.16 12.5 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair RsgA_GTPase PF03193.16 RJW70260.1 - 0.024 14.6 0.0 7.5 6.4 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase EF-hand_5 PF13202.6 RJW70260.1 - 0.026 14.0 0.2 0.098 12.2 0.2 2.0 1 0 0 1 1 1 0 EF hand FeoB_N PF02421.18 RJW70260.1 - 0.071 12.6 0.1 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B EF-hand_8 PF13833.6 RJW70260.1 - 0.082 12.8 0.2 3.2 7.7 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair AAA_24 PF13479.6 RJW70260.1 - 0.091 12.5 0.3 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 RJW70260.1 - 0.1 11.9 0.1 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 AIG1 family PIN_5 PF08745.11 RJW70260.1 - 0.11 11.9 1.5 0.5 9.7 0.0 2.4 3 0 0 3 3 3 0 PINc domain ribonuclease Roc PF08477.13 RJW70260.1 - 0.15 12.3 0.0 4.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FA_desaturase PF00487.24 RJW70264.1 - 1.2e-21 77.7 25.2 1.7e-21 77.2 25.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 RJW70264.1 - 1.2e-17 63.1 0.8 2.5e-17 62.1 0.8 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Metallopep PF12044.8 RJW70264.1 - 0.13 10.8 0.5 0.18 10.3 0.5 1.1 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.9 RJW70264.1 - 7.6 5.4 6.2 0.56 9.1 0.2 1.9 2 0 0 2 2 2 0 Peptidase M66 zf-C2H2 PF00096.26 RJW70266.1 - 2.8e-32 109.3 78.7 0.00011 22.4 0.3 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW70266.1 - 2.1e-22 77.9 78.2 0.00067 20.3 0.3 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW70266.1 - 3e-15 55.8 72.9 0.041 14.3 0.1 12.2 12 2 0 12 12 11 9 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW70266.1 - 5.7e-12 45.6 40.8 0.074 13.4 0.1 9.3 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW70266.1 - 1.9e-09 37.3 58.2 0.13 12.3 0.2 11.3 10 1 0 10 10 10 5 C2H2-type zinc finger zf_UBZ PF18439.1 RJW70266.1 - 4.4e-08 32.6 28.6 0.38 10.4 0.0 8.6 8 0 0 8 8 8 5 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 RJW70266.1 - 4e-07 30.2 38.6 0.29 11.6 0.0 9.9 10 1 0 10 10 10 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RJW70266.1 - 0.0031 17.2 0.0 0.0031 17.2 0.0 8.2 9 0 0 9 9 9 3 zinc-finger C2H2-type Rad50_zn_hook PF04423.14 RJW70266.1 - 0.0059 16.4 19.2 0.6 10.0 0.0 6.5 7 0 0 7 7 7 2 Rad50 zinc hook motif zf-C2H2_3rep PF18868.1 RJW70266.1 - 0.0092 16.7 26.9 3 8.5 1.1 6.9 2 2 4 7 7 7 2 Zinc finger C2H2-type, 3 repeats Med27 PF11571.8 RJW70266.1 - 0.02 15.3 2.6 0.02 15.3 2.6 4.6 4 2 1 5 5 5 0 Mediator complex subunit 27 zf-C2HC_2 PF13913.6 RJW70266.1 - 0.02 14.8 33.2 1.4 8.9 0.5 7.5 8 0 0 8 8 7 0 zinc-finger of a C2HC-type zf-RING_7 PF02591.15 RJW70266.1 - 0.15 12.2 27.1 1.1 9.4 0.1 7.8 9 0 0 9 9 8 0 C4-type zinc ribbon domain zf-C2H2_9 PF16293.5 RJW70266.1 - 0.17 11.8 19.5 6.3 6.7 0.1 6.5 5 3 2 7 7 7 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 RJW70266.1 - 0.18 12.6 0.4 0.15 12.8 0.9 6.1 3 2 3 6 6 6 0 zinc-ribbon family Ribosomal_S14 PF00253.21 RJW70266.1 - 0.21 11.4 0.1 0.21 11.4 0.1 3.8 3 1 1 4 4 4 0 Ribosomal protein S14p/S29e DUF2256 PF10013.9 RJW70266.1 - 0.73 10.0 25.7 53 4.1 0.2 8.8 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) XPA_N PF01286.18 RJW70266.1 - 0.78 9.8 0.0 0.78 9.8 0.0 8.3 9 0 0 9 9 8 0 XPA protein N-terminal zinc-ribbons_6 PF07191.12 RJW70266.1 - 0.98 9.5 40.6 0.84 9.7 4.2 7.4 4 4 2 6 6 6 0 zinc-ribbons zf-C2H2_2 PF12756.7 RJW70266.1 - 1.5 9.2 48.9 11 6.4 5.4 8.7 2 2 4 7 7 7 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RJW70266.1 - 2.4 8.3 44.0 0.52 10.5 2.5 8.3 6 3 4 10 10 10 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 RJW70266.1 - 3.6 7.9 29.0 5.9 7.3 0.3 7.6 8 0 0 8 8 7 0 zinc-ribbon MMtag PF10159.9 RJW70266.1 - 3.8 7.9 4.8 5.4 7.4 0.1 2.9 3 0 0 3 3 3 0 Multiple myeloma tumor-associated FTH PF01827.27 RJW70267.1 - 0.092 12.5 1.8 0.24 11.2 1.8 1.7 1 1 0 1 1 1 0 FTH domain ARTD15_N PF18084.1 RJW70267.1 - 0.26 11.6 2.4 4.2 7.7 0.2 2.6 2 1 1 3 3 3 0 ARTD15 N-terminal domain zf-LITAF-like PF10601.9 RJW70268.1 - 5.3e-20 71.5 10.8 7.4e-20 71.0 10.8 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DUF4428 PF14471.6 RJW70268.1 - 0.00037 20.3 2.3 0.13 12.2 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) zf-Di19 PF05605.12 RJW70268.1 - 0.0058 16.9 2.2 1.9 8.8 0.1 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DUF5318 PF17249.2 RJW70268.1 - 0.036 13.8 0.5 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5318) zf-C2H2_6 PF13912.6 RJW70268.1 - 0.47 10.5 2.2 10 6.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger MCU PF04678.13 RJW70269.1 - 2e-65 220.2 0.5 2.6e-65 219.8 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Ribosomal_L29 PF00831.23 RJW70269.1 - 0.12 12.4 0.5 0.39 10.7 0.5 1.9 1 0 0 1 1 1 0 Ribosomal L29 protein PRKG1_interact PF15898.5 RJW70269.1 - 0.21 12.5 2.5 1.5 9.8 0.6 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Herpes_U44 PF04533.13 RJW70270.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Herpes virus U44 protein Amastin PF07344.11 RJW70271.1 - 5.1e-05 23.2 10.9 5.1e-05 23.2 10.9 2.3 1 1 1 2 2 2 1 Amastin surface glycoprotein DUF2569 PF10754.9 RJW70271.1 - 0.00098 19.6 16.4 0.0014 19.0 16.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2569) CsgF PF10614.9 RJW70271.1 - 0.06 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein GRP PF07172.11 RJW70271.1 - 0.96 10.2 1.6 54 4.6 0.5 2.5 2 0 0 2 2 2 0 Glycine rich protein family DUF5090 PF17009.5 RJW70271.1 - 1.5 8.7 17.6 0.28 11.1 12.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) DUF2070 PF09843.9 RJW70271.1 - 4 5.6 20.3 4.6 5.4 20.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tmemb_55A PF09788.9 RJW70271.1 - 9.7 5.2 14.8 8 5.5 4.0 2.0 1 1 1 2 2 2 0 Transmembrane protein 55A Ank_2 PF12796.7 RJW70272.1 - 1.2e-63 211.7 14.7 2.2e-13 50.6 0.0 10.0 5 4 3 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 RJW70272.1 - 1.4e-53 177.1 40.5 1.7e-08 34.5 0.1 14.3 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 RJW70272.1 - 6.2e-47 157.0 27.5 2.5e-07 30.8 0.1 12.8 9 3 4 13 13 13 11 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW70272.1 - 1.3e-46 156.4 17.2 2e-07 31.4 0.0 11.7 9 2 4 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW70272.1 - 2.4e-46 150.3 24.5 0.00029 21.0 0.1 14.4 14 0 0 14 14 14 13 Ankyrin repeat Amastin PF07344.11 RJW70274.1 - 2 8.2 18.6 0.12 12.2 11.2 2.3 1 1 1 2 2 2 0 Amastin surface glycoprotein ABC2_membrane_5 PF13346.6 RJW70274.1 - 2 7.9 18.7 2.8 7.4 18.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein TssN PF17555.2 RJW70274.1 - 3 7.1 10.9 3.5 6.9 7.4 1.9 1 1 1 2 2 2 0 Type VI secretion system, TssN DUF2070 PF09843.9 RJW70274.1 - 7.6 4.7 13.2 9.2 4.4 13.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) EMP70 PF02990.16 RJW70275.1 - 0.084 11.5 7.4 0.096 11.3 7.4 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 TssN PF17555.2 RJW70275.1 - 0.39 10.1 10.4 0.41 10.0 7.0 1.9 1 1 1 2 2 2 0 Type VI secretion system, TssN DUF973 PF06157.11 RJW70275.1 - 0.42 9.6 9.4 0.55 9.2 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) HlyIII PF03006.20 RJW70275.1 - 0.57 9.8 11.9 1.8 8.2 0.6 2.5 1 1 1 2 2 2 0 Haemolysin-III related DUF2070 PF09843.9 RJW70275.1 - 1.1 7.5 11.3 1.4 7.1 11.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FtsX PF02687.21 RJW70275.1 - 8.8 6.9 22.6 0.68 10.4 7.7 2.3 1 1 1 2 2 2 0 FtsX-like permease family ABC2_membrane_5 PF13346.6 RJW70275.1 - 9.3 5.7 18.1 14 5.1 18.1 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Cyto_heme_lyase PF01265.17 RJW70277.1 - 2.4e-63 214.4 2.7 9.6e-63 212.5 2.7 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase RT_RNaseH_2 PF17919.1 RJW70277.1 - 7.1e-24 83.7 0.3 2.8e-23 81.8 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW70277.1 - 9.6e-14 51.6 0.0 2.6e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RJW70277.1 - 0.01 16.0 0.0 0.34 11.1 0.0 3.0 2 1 1 3 3 3 0 Integrase core domain RVT_1 PF00078.27 RJW70277.1 - 0.08 12.4 0.0 0.37 10.3 0.0 1.9 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RPEL PF02755.15 RJW70279.1 - 1.5e-12 46.7 11.9 0.00011 21.8 5.3 3.9 4 0 0 4 4 4 3 RPEL repeat SAP PF02037.27 RJW70279.1 - 0.0002 21.0 0.2 0.00057 19.6 0.2 1.8 1 0 0 1 1 1 1 SAP domain AhpC-TSA PF00578.21 RJW70280.1 - 2.4e-26 92.1 0.0 2.8e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RJW70280.1 - 2.4e-06 27.3 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Ank_2 PF12796.7 RJW70281.1 - 1.1e-46 157.3 12.2 2.5e-17 63.3 0.4 6.1 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW70281.1 - 3.3e-41 139.1 14.2 2.5e-11 43.9 0.0 7.8 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 RJW70281.1 - 1.3e-35 120.3 22.7 9.4e-06 25.9 0.1 10.3 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 RJW70281.1 - 2.5e-33 110.3 19.7 4e-06 26.8 0.2 10.3 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 RJW70281.1 - 4.9e-31 106.4 16.8 9.2e-09 35.4 0.1 7.3 5 1 2 7 7 7 6 Ankyrin repeats (many copies) DUF2520 PF10728.9 RJW70281.1 - 9.2e-05 22.2 3.6 0.073 12.8 0.7 3.9 2 2 2 4 4 4 1 Domain of unknown function (DUF2520) GATase_7 PF13537.6 RJW70281.1 - 0.013 15.4 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Glutamine amidotransferase domain RabGAP-TBC PF00566.18 RJW70282.1 - 2.2e-13 50.4 0.2 3.4e-13 49.7 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 RJW70282.1 - 5.6e-07 30.0 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain GlnD_UR_UTase PF08335.11 RJW70284.1 - 0.0029 17.7 0.5 3.2 7.9 0.1 2.2 2 0 0 2 2 2 2 GlnD PII-uridylyltransferase EF-hand_12 PF17901.1 RJW70284.1 - 0.011 16.2 0.2 1.7 9.2 0.0 2.3 2 0 0 2 2 2 0 EF-hand fold domain DUF2243 PF10002.9 RJW70284.1 - 0.048 13.8 0.1 15 5.7 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) Pkinase PF00069.25 RJW70286.1 - 6.3e-40 137.2 0.0 1.9e-38 132.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW70286.1 - 7.7e-21 74.5 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW70286.1 - 4.1e-06 25.8 0.1 1.1e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RJW70286.1 - 0.0001 21.7 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.18 RJW70286.1 - 0.00022 21.3 0.0 0.00072 19.7 0.0 1.8 1 0 0 1 1 1 1 POLO box duplicated region APH PF01636.23 RJW70286.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cluap1 PF10234.9 RJW70287.1 - 1.5e-101 339.3 7.8 1.5e-101 339.3 7.8 1.4 2 0 0 2 2 2 1 Clusterin-associated protein-1 Imm49 PF15575.6 RJW70287.1 - 0.019 14.7 1.1 0.052 13.3 0.1 1.8 1 1 1 2 2 2 0 Immunity protein 49 Atg14 PF10186.9 RJW70287.1 - 0.067 12.3 5.0 0.1 11.7 5.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2457 PF10446.9 RJW70287.1 - 0.096 11.8 27.5 0.29 10.2 27.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 RJW70287.1 - 0.38 10.7 23.5 0.011 15.7 17.3 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 RJW70287.1 - 3.3 5.7 27.9 7.6 4.5 27.9 1.5 1 0 0 1 1 1 0 DNA polymerase phi ADIP PF11559.8 RJW70288.1 - 3.4e-13 49.9 10.9 3.4e-13 49.9 10.9 3.1 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding Sec34 PF04136.15 RJW70288.1 - 0.25 11.2 9.1 0.66 9.9 0.2 2.6 2 0 0 2 2 2 0 Sec34-like family DUF724 PF05266.14 RJW70288.1 - 3.5 7.4 8.6 1.3 8.8 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 RJW70288.1 - 5.5 7.1 9.9 7.1 6.7 0.2 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) Pico_P2B PF01552.17 RJW70290.1 - 0.0082 16.3 0.1 0.0093 16.1 0.1 1.1 1 0 0 1 1 1 1 Picornavirus 2B protein HRG PF16954.5 RJW70290.1 - 0.14 12.5 6.2 0.22 12.0 5.5 1.6 1 1 1 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF3220 PF11516.8 RJW70291.1 - 0.087 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) E1_DerP2_DerF2 PF02221.15 RJW70292.1 - 0.041 14.3 0.8 0.42 11.0 0.7 2.1 1 1 1 2 2 2 0 ML domain Aa_trans PF01490.18 RJW70293.1 - 7.7e-56 189.5 29.2 9.8e-56 189.2 29.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.15 RJW70293.1 - 6.3 7.3 0.0 6.3 7.3 0.0 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF202) 7tm_1 PF00001.21 RJW70294.1 - 1.5e-12 47.4 9.3 3.2e-12 46.3 9.3 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW70294.1 - 0.0003 20.3 9.5 0.00048 19.6 9.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RJW70294.1 - 0.0096 15.7 5.6 0.017 14.9 5.1 1.5 1 1 0 1 1 1 1 Olfactory receptor hDGE_amylase PF14701.6 RJW70295.1 - 5e-135 451.0 0.0 6.3e-135 450.7 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain hGDE_central PF14702.6 RJW70295.1 - 1.2e-77 261.0 0.0 1.8e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 RJW70295.1 - 4.8e-16 58.7 0.1 9.4e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme GDE_C PF06202.14 RJW70295.1 - 1.1e-10 41.1 0.1 1.6e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase GreA_GreB_N PF03449.15 RJW70295.1 - 0.069 13.3 0.6 0.15 12.2 0.6 1.5 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal AAA PF00004.29 RJW70296.1 - 1.2e-96 320.2 0.0 3.6e-47 160.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW70296.1 - 5.1e-22 77.4 9.3 1.7e-11 43.7 1.5 3.4 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 RJW70296.1 - 5.1e-16 58.6 0.0 1.4e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 RJW70296.1 - 2.6e-13 50.0 0.0 1.8e-05 24.5 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RJW70296.1 - 4.9e-13 49.8 3.2 0.0002 21.8 0.1 5.0 4 2 0 4 4 3 2 AAA ATPase domain AAA_2 PF07724.14 RJW70296.1 - 5.9e-11 42.8 0.0 3.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RJW70296.1 - 8.5e-11 42.2 0.0 4.7e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 RJW70296.1 - 1.2e-09 37.8 0.0 2.5e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 RJW70296.1 - 2e-09 37.9 0.5 0.025 14.8 0.1 4.4 3 2 1 4 4 3 2 AAA domain AAA_5 PF07728.14 RJW70296.1 - 2.3e-09 37.4 0.3 0.00065 19.7 0.0 3.5 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 RJW70296.1 - 2.3e-08 33.7 0.0 0.002 17.4 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Vps4_C PF09336.10 RJW70296.1 - 5.4e-08 32.7 0.4 7.5e-05 22.7 0.0 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 RJW70296.1 - 1.1e-07 32.5 0.0 0.03 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 RJW70296.1 - 3e-07 30.8 0.0 0.0065 16.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 RJW70296.1 - 5.3e-07 29.7 0.0 0.038 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 RJW70296.1 - 5.4e-07 29.2 0.1 0.024 14.0 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RJW70296.1 - 1.7e-06 27.9 0.0 0.068 12.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Parvo_NS1 PF01057.17 RJW70296.1 - 3.2e-06 26.4 0.1 0.043 12.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 RJW70296.1 - 7.7e-06 26.0 0.1 0.3 11.0 0.0 3.6 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 RJW70296.1 - 7.7e-06 26.2 0.2 0.19 12.0 0.0 3.0 3 1 1 4 4 2 2 AAA domain AAA_7 PF12775.7 RJW70296.1 - 9.9e-06 25.2 0.0 0.085 12.4 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 RJW70296.1 - 1.4e-05 24.5 0.3 0.59 9.4 0.0 3.3 2 1 1 3 3 3 2 KaiC ABC_tran PF00005.27 RJW70296.1 - 1.5e-05 25.6 0.0 0.015 15.8 0.0 3.2 2 1 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 RJW70296.1 - 8e-05 22.3 2.6 2.6 7.6 0.1 3.7 2 2 1 4 4 4 1 AAA domain AAA_24 PF13479.6 RJW70296.1 - 8.2e-05 22.4 0.0 0.14 11.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 RJW70296.1 - 0.00011 22.1 0.0 0.42 10.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein Sigma54_activat PF00158.26 RJW70296.1 - 0.00012 21.9 0.0 0.38 10.4 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 RJW70296.1 - 0.00013 22.0 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 RJW70296.1 - 0.00013 22.4 0.0 1.1 9.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 RJW70296.1 - 0.00016 21.5 0.0 0.0032 17.3 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 RJW70296.1 - 0.00018 20.8 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 RJW70296.1 - 0.00028 20.8 0.1 0.38 10.6 0.0 3.4 3 1 1 4 4 4 1 NACHT domain NB-ARC PF00931.22 RJW70296.1 - 0.00037 19.8 0.0 0.26 10.4 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain ResIII PF04851.15 RJW70296.1 - 0.00051 20.1 0.0 0.055 13.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 RJW70296.1 - 0.00078 18.8 0.0 0.65 9.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Sigma54_activ_2 PF14532.6 RJW70296.1 - 0.00082 19.5 0.0 2.3 8.4 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 RJW70296.1 - 0.0015 18.1 0.2 1.9 7.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 RJW70296.1 - 0.0017 17.7 0.0 0.55 9.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 RJW70296.1 - 0.0024 17.8 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 RJW70296.1 - 0.0033 17.3 0.2 2.4 7.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 RJW70296.1 - 0.0062 16.5 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 RJW70296.1 - 0.0071 16.7 0.7 3.6 7.9 0.1 3.0 2 1 1 3 3 2 1 AAA domain AAA_30 PF13604.6 RJW70296.1 - 0.025 14.3 0.5 3.9 7.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 RJW70296.1 - 0.041 13.8 0.1 6.5 6.6 0.0 3.2 3 0 0 3 3 3 0 NTPase SKI PF01202.22 RJW70296.1 - 0.11 12.6 0.0 9.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 RJW70296.1 - 0.13 11.9 0.0 27 4.4 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase PduV-EutP PF10662.9 RJW70296.1 - 0.2 11.4 0.0 4 7.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IFT57 PF10498.9 RJW70297.1 - 2.6e-123 411.6 4.9 6e-122 407.1 4.9 2.0 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 DUF1664 PF07889.12 RJW70297.1 - 0.025 14.6 0.4 0.07 13.2 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ADIP PF11559.8 RJW70297.1 - 0.032 14.3 4.6 0.094 12.8 0.5 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SpecificRecomb PF10136.9 RJW70297.1 - 0.034 12.5 1.1 0.043 12.1 1.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase Fez1 PF06818.15 RJW70297.1 - 0.038 14.4 4.7 0.16 12.4 4.6 2.0 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 RJW70297.1 - 0.048 12.5 2.1 0.089 11.7 2.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.6 RJW70297.1 - 0.09 13.2 1.6 0.22 11.9 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) GAS PF13851.6 RJW70297.1 - 0.19 11.0 2.6 0.51 9.7 2.6 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4618 PF15397.6 RJW70297.1 - 0.46 9.9 4.6 0.77 9.1 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Phage_Mu_Gam PF07352.12 RJW70297.1 - 0.59 10.0 2.7 1.6 8.6 0.5 2.4 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein CdvA PF18822.1 RJW70297.1 - 0.88 9.4 5.7 2.4 8.0 5.7 1.8 1 1 0 1 1 1 0 CdvA-like coiled-coil domain FapA PF03961.13 RJW70297.1 - 0.95 8.0 2.5 2.1 6.8 2.3 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A FTA4 PF13093.6 RJW70297.1 - 1.9 8.3 6.3 2.2 8.1 5.1 1.7 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 rve PF00665.26 RJW70298.1 - 0.00049 20.3 0.0 0.00087 19.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF2340 PF10209.9 RJW70299.1 - 3.1e-28 98.6 0.0 3.7e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Anoctamin PF04547.12 RJW70300.1 - 1.1e-34 120.1 3.7 1.8e-34 119.4 3.7 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel Ank_4 PF13637.6 RJW70300.1 - 6.7e-13 48.9 0.0 2.1e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW70300.1 - 1.1e-11 45.2 0.0 2.9e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW70300.1 - 1.1e-10 41.5 0.1 6.8e-06 26.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW70300.1 - 2e-10 40.0 0.1 4.9e-07 29.6 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RJW70300.1 - 1.2e-09 38.1 0.1 3.6e-06 27.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat DUF2975 PF11188.8 RJW70300.1 - 1.5 8.7 7.0 0.66 9.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DDE_2 PF02914.15 RJW70303.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase zf-AN1 PF01428.16 RJW70303.1 - 0.19 11.9 6.6 0.43 10.8 6.6 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger FYVE_2 PF02318.16 RJW70303.1 - 5.6 7.2 12.6 14 6.0 0.3 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger TAP42 PF04177.12 RJW70304.1 - 8.4e-44 150.0 0.6 9.7e-44 149.8 0.6 1.0 1 0 0 1 1 1 1 TAP42-like family Fer2 PF00111.27 RJW70305.1 - 1.1e-10 41.3 0.0 1.1e-10 41.3 0.0 1.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Yippee-Mis18 PF03226.14 RJW70305.1 - 0.024 14.9 0.1 0.037 14.2 0.1 1.4 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ISP3_C PF18045.1 RJW70305.1 - 0.036 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 ISP3 C-terminal ISP1_C PF18161.1 RJW70305.1 - 0.054 13.5 0.1 0.69 9.9 0.0 2.0 2 0 0 2 2 2 0 ISP1 C-terminal Ribosomal_S24e PF01282.19 RJW70306.1 - 5.3e-32 109.6 0.0 1.3e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S24e YtxH PF12732.7 RJW70306.1 - 0.35 11.4 2.5 0.43 11.1 1.0 1.8 2 0 0 2 2 2 0 YtxH-like protein SRP54 PF00448.22 RJW70307.1 - 5.7e-76 254.5 0.1 9e-76 253.9 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 RJW70307.1 - 4.1e-24 85.1 3.9 7.4e-24 84.3 0.1 3.0 1 1 1 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 RJW70307.1 - 1.3e-17 63.8 1.3 1.3e-17 63.8 1.3 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 RJW70307.1 - 3.7e-06 26.7 0.4 1.9e-05 24.3 0.4 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 RJW70307.1 - 4.6e-05 23.5 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 RJW70307.1 - 7.4e-05 22.9 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RJW70307.1 - 0.0003 21.2 0.0 0.0024 18.3 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 RJW70307.1 - 0.0014 19.0 0.3 0.39 11.2 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 RJW70307.1 - 0.0027 17.2 1.0 0.95 8.9 0.1 2.7 2 1 1 3 3 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 RJW70307.1 - 0.0036 17.6 1.4 0.059 13.6 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 RJW70307.1 - 0.0038 17.0 0.0 0.0077 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RJW70307.1 - 0.0045 16.3 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF2209 PF09974.9 RJW70307.1 - 0.0046 17.3 0.3 0.011 16.1 0.3 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) AAA_5 PF07728.14 RJW70307.1 - 0.0059 16.6 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 RJW70307.1 - 0.007 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ResIII PF04851.15 RJW70307.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 RJW70307.1 - 0.011 15.8 0.1 0.061 13.4 0.1 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase 6PF2K PF01591.18 RJW70307.1 - 0.012 14.9 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_17 PF13207.6 RJW70307.1 - 0.022 15.2 0.4 0.12 12.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RJW70307.1 - 0.022 15.1 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RJW70307.1 - 0.024 15.2 0.0 0.06 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 RJW70307.1 - 0.027 14.3 0.2 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop LpxB PF02684.15 RJW70307.1 - 0.03 13.2 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase AAA_28 PF13521.6 RJW70307.1 - 0.034 14.4 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 RJW70307.1 - 0.069 12.3 0.2 0.53 9.4 0.0 2.1 2 1 0 2 2 2 0 G-protein alpha subunit AAA_31 PF13614.6 RJW70307.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain VirE PF05272.11 RJW70307.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E AAA_24 PF13479.6 RJW70307.1 - 0.09 12.5 0.1 0.23 11.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 RJW70307.1 - 0.1 12.2 0.1 0.29 10.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 RJW70307.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 RJW70307.1 - 0.13 12.1 0.1 0.36 10.7 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.10 RJW70307.1 - 0.14 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_7 PF12775.7 RJW70307.1 - 0.16 11.5 0.1 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ras PF00071.22 RJW70308.1 - 9.5e-25 87.1 0.2 1.6e-24 86.3 0.2 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW70308.1 - 1.1e-05 25.6 0.0 2.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RJW70308.1 - 0.024 14.1 0.2 0.037 13.6 0.2 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 RJW70308.1 - 0.076 13.1 0.1 0.15 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain SHIPPO-rpt PF07004.12 RJW70309.1 - 2e-10 41.1 27.7 0.14 13.1 0.1 6.5 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat SET PF00856.28 RJW70310.1 - 1.4e-09 38.6 0.0 5.3e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 SET domain Fer4_11 PF13247.6 RJW70310.1 - 1.4 9.1 9.0 0.099 12.8 0.7 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain LRR_4 PF12799.7 RJW70311.1 - 6.7e-10 39.1 23.1 9.1e-07 29.1 4.5 4.7 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW70311.1 - 1.2e-08 34.6 19.6 0.0015 18.2 4.2 4.1 3 0 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 RJW70311.1 - 2e-08 34.0 2.6 9e-08 31.8 2.6 2.2 1 0 0 1 1 1 1 Leucine-rich repeat DUF3783 PF12646.7 RJW70311.1 - 0.078 12.9 0.1 0.35 10.9 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) DUF2935 PF11155.8 RJW70311.1 - 0.14 12.5 18.3 4.3 7.7 5.8 4.7 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) LRR_6 PF13516.6 RJW70311.1 - 0.98 9.6 20.9 9.2 6.6 0.6 5.5 5 0 0 5 5 5 0 Leucine Rich repeat CNH PF00780.22 RJW70312.1 - 5.3e-35 121.4 0.0 8.5e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 CNH domain PBD PF00786.28 RJW70312.1 - 0.082 13.3 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 P21-Rho-binding domain eIF-5_eIF-2B PF01873.17 RJW70315.1 - 3.9e-37 126.7 0.4 8.8e-37 125.6 0.1 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 GEN1_C PF18380.1 RJW70315.1 - 0.56 11.1 4.2 0.29 12.0 1.6 1.9 1 1 1 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain DNA_RNApol_7kD PF03604.13 RJW70315.1 - 1.3 8.8 5.1 3.9 7.2 5.1 1.8 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit JIP_LZII PF16471.5 RJW70318.1 - 4.2e-18 65.3 5.2 4.2e-18 65.3 5.2 3.1 3 1 1 4 4 4 1 JNK-interacting protein leucine zipper II Jnk-SapK_ap_N PF09744.9 RJW70318.1 - 7e-05 23.1 16.7 0.00022 21.5 0.3 2.9 3 0 0 3 3 3 2 JNK_SAPK-associated protein-1 RILP PF11461.8 RJW70318.1 - 0.0088 16.3 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 Rab interacting lysosomal protein DUF1664 PF07889.12 RJW70318.1 - 0.015 15.3 0.8 0.067 13.2 0.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 RJW70318.1 - 0.085 12.7 3.0 7.1 6.4 0.5 3.3 3 1 0 3 3 3 0 Phage minor structural protein GP20 CALCOCO1 PF07888.11 RJW70318.1 - 0.17 10.7 16.7 0.0073 15.2 4.9 3.0 3 0 0 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_TATA_bd PF12325.8 RJW70318.1 - 0.19 11.9 16.9 1.8 8.8 4.1 4.0 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF2353 PF09789.9 RJW70318.1 - 0.26 10.6 10.9 0.075 12.4 2.9 2.9 3 1 0 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) FlxA PF14282.6 RJW70318.1 - 0.27 11.2 1.9 0.97 9.5 0.5 2.5 3 0 0 3 3 3 0 FlxA-like protein CCDC-167 PF15188.6 RJW70318.1 - 0.46 10.9 5.3 0.21 12.0 2.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ADIP PF11559.8 RJW70318.1 - 0.65 10.1 12.6 6 6.9 5.4 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Prefoldin PF02996.17 RJW70318.1 - 1 9.3 8.6 0.83 9.6 0.9 3.5 3 1 1 4 4 4 0 Prefoldin subunit APG6_N PF17675.1 RJW70318.1 - 1.1 9.8 17.7 0.44 11.1 7.1 3.4 3 1 0 3 3 3 0 Apg6 coiled-coil region CLZ PF16526.5 RJW70318.1 - 2.6 8.5 9.2 3.3 8.1 0.3 3.0 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 RJW70318.1 - 4 7.5 17.5 1.9 8.5 1.9 4.1 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DLP_helical PF18709.1 RJW70318.1 - 4.1 6.5 6.9 0.88 8.7 2.0 2.0 2 0 0 2 2 2 0 Dynamin-like helical domain Prefoldin_2 PF01920.20 RJW70318.1 - 5.2 7.1 14.6 82 3.2 0.1 4.1 3 1 0 3 3 3 0 Prefoldin subunit WD40 PF00400.32 RJW70319.1 - 0.0064 17.3 2.2 15 6.6 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat fn3 PF00041.21 RJW70320.1 - 1.7e-17 63.5 14.5 0.00043 20.6 0.1 5.2 5 0 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW70320.1 - 0.046 14.3 4.1 0.47 11.0 0.1 3.5 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain DUF4998 PF16389.5 RJW70320.1 - 0.051 13.2 0.0 7.7 6.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function Interfer-bind PF09294.10 RJW70320.1 - 0.12 12.7 0.1 9.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 RJW70321.1 - 1.3e-18 67.1 6.2 6.8e-05 23.1 0.0 5.1 5 0 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW70321.1 - 0.0037 17.8 1.0 32 5.2 0.0 4.8 4 1 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain DUF4959 PF16323.5 RJW70321.1 - 0.038 14.3 0.0 3.5 8.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4959) DUF4998 PF16389.5 RJW70321.1 - 0.044 13.4 0.2 10 5.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function HECT PF00632.25 RJW70322.1 - 8.5e-92 307.9 0.0 1.8e-91 306.8 0.0 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) 7tm_1 PF00001.21 RJW70324.1 - 0.075 12.3 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4083 PF13314.6 RJW70324.1 - 1.6 8.8 3.7 12 5.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) fn3 PF00041.21 RJW70326.1 - 9.9e-19 67.5 6.4 0.0034 17.7 0.0 5.1 5 0 0 5 5 5 5 Fibronectin type III domain Tissue_fac PF01108.17 RJW70326.1 - 3.3e-05 23.7 0.2 0.016 15.0 0.0 3.4 3 1 0 3 3 3 1 Tissue factor DUF4998 PF16389.5 RJW70326.1 - 0.05 13.2 0.0 6.3 6.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF756 PF05506.12 RJW70326.1 - 0.057 14.3 2.5 2.4 9.1 0.0 3.8 3 2 1 4 4 4 0 Domain of unknown function (DUF756) PDZ PF00595.24 RJW70327.1 - 6.5e-07 29.6 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW70327.1 - 1.4e-05 24.9 0.0 4e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain MGTL PF17059.5 RJW70327.1 - 3.9 7.4 6.7 0.3 10.9 1.1 2.2 2 0 0 2 2 2 0 MgtA leader peptide zf-C2H2 PF00096.26 RJW70328.1 - 2.9e-09 36.9 24.0 7e-05 23.1 1.5 5.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW70328.1 - 4.4e-07 30.2 23.7 0.0043 17.8 1.6 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW70328.1 - 5.5e-07 29.7 0.9 5.5e-07 29.7 0.9 4.3 4 0 0 4 4 4 1 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 RJW70328.1 - 0.0074 15.9 8.8 0.44 10.2 0.3 3.6 2 1 1 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 RJW70328.1 - 0.01 15.8 1.2 0.01 15.8 1.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger ADK_lid PF05191.14 RJW70328.1 - 0.1 12.6 6.7 0.83 9.7 1.1 3.7 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-met PF12874.7 RJW70328.1 - 0.16 12.4 14.7 0.58 10.6 1.0 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type ChitinaseA_N PF08329.10 RJW70328.1 - 0.17 11.5 0.3 3.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Zn_ribbon_SprT PF17283.2 RJW70328.1 - 0.21 11.5 8.1 4.5 7.3 0.7 3.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_3rep PF18868.1 RJW70328.1 - 0.27 11.9 5.8 0.12 13.0 1.6 2.6 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats FpoO PF10621.9 RJW70328.1 - 0.33 11.3 5.5 13 6.2 3.7 2.8 2 1 1 3 3 2 0 F420H2 dehydrogenase subunit FpoO TF_Zn_Ribbon PF08271.12 RJW70328.1 - 0.33 10.5 15.7 0.29 10.7 1.6 3.9 3 1 0 3 3 3 0 TFIIB zinc-binding FYVE PF01363.21 RJW70328.1 - 0.41 10.8 16.0 0.23 11.6 11.8 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf_UBZ PF18439.1 RJW70328.1 - 0.67 9.6 8.0 1.5 8.5 0.5 3.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 RJW70328.1 - 0.9 9.7 10.3 7.3 6.8 0.0 3.5 2 1 2 4 4 4 0 Zinc ribbon domain DZR PF12773.7 RJW70328.1 - 1.8 8.7 10.9 1.6e+02 2.4 10.9 3.1 1 1 0 1 1 1 0 Double zinc ribbon C1_2 PF03107.16 RJW70328.1 - 2.5 8.5 11.3 47 4.4 0.3 4.0 3 1 0 3 3 3 0 C1 domain DUF629 PF04780.12 RJW70328.1 - 8 4.9 7.9 0.82 8.1 0.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF629) RCC1 PF00415.18 RJW70329.1 - 7.8e-25 87.2 0.8 1.1e-11 45.2 0.0 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RJW70329.1 - 6.7e-20 70.4 6.2 3e-09 36.4 0.3 2.8 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat DisA_N PF02457.16 RJW70329.1 - 0.026 14.1 0.3 0.079 12.6 0.0 1.8 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding Tmemb_161AB PF10268.9 RJW70330.1 - 3.9e-51 174.2 9.6 5e-51 173.8 9.6 1.2 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB RVT_1 PF00078.27 RJW70331.1 - 1.6e-11 44.2 0.0 2.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) XPG_N PF00752.17 RJW70331.1 - 0.00053 20.4 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain RP-C_C PF11800.8 RJW70331.1 - 0.21 11.7 2.5 0.36 10.9 2.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region RRM_1 PF00076.22 RJW70332.1 - 1.3e-13 50.5 0.0 7.9e-06 25.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 RJW70333.1 - 2.9e-09 37.4 3.1 0.00039 21.2 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Transposase_28 PF04195.12 RJW70335.1 - 0.00099 19.3 0.3 0.003 17.7 0.3 1.8 1 0 0 1 1 1 1 Putative gypsy type transposon MRP-S31 PF15433.6 RJW70336.1 - 1.7e-42 146.2 0.9 2.5e-42 145.7 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 RVT_1 PF00078.27 RJW70336.1 - 2.8e-21 76.1 0.0 4.3e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GAT PF03127.14 RJW70338.1 - 0.052 13.9 0.2 0.41 11.0 0.3 2.2 3 0 0 3 3 3 0 GAT domain DHHC PF01529.20 RJW70339.1 - 1.6e-31 109.2 8.5 1.6e-31 109.2 8.5 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase SH3_2 PF07653.17 RJW70339.1 - 0.00065 19.3 1.0 0.0028 17.3 0.2 2.4 2 1 0 2 2 2 1 Variant SH3 domain YlaC PF10777.9 RJW70339.1 - 2.4 8.0 4.2 0.42 10.5 0.1 1.8 2 0 0 2 2 2 0 Inner membrane protein YlaC Peptidase_C78 PF07910.13 RJW70340.1 - 1e-30 106.8 0.0 3.5e-17 62.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family C78 Phage_portal_2 PF05136.13 RJW70340.1 - 0.0014 17.9 0.6 0.021 14.0 0.0 2.2 2 0 0 2 2 2 1 Phage portal protein, lambda family LIM PF00412.22 RJW70341.1 - 7e-35 119.1 43.5 2.1e-13 50.3 7.1 4.5 5 0 0 5 5 5 4 LIM domain Vps55 PF04133.14 RJW70343.1 - 3.2e-18 65.8 4.3 3.6e-18 65.6 4.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DuoxA PF10204.9 RJW70343.1 - 0.018 14.1 0.5 0.02 13.9 0.5 1.2 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF1232 PF06803.12 RJW70346.1 - 2.5e-07 30.3 7.8 4.7e-07 29.5 7.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) zf-RING_2 PF13639.6 RJW70346.1 - 5.7e-06 26.6 13.7 9.7e-06 25.8 13.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RJW70346.1 - 9.9e-05 22.1 8.3 0.00016 21.5 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW70346.1 - 0.0004 20.2 11.2 0.00068 19.5 11.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW70346.1 - 0.00059 19.6 11.5 0.0016 18.2 11.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW70346.1 - 0.0068 16.3 11.0 0.022 14.7 11.1 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RJW70346.1 - 0.0089 16.2 11.6 0.019 15.1 11.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RJW70346.1 - 0.013 15.5 7.6 0.013 15.5 7.6 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Baculo_IE-1 PF05290.11 RJW70346.1 - 0.045 13.7 5.0 0.078 12.9 5.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 RJW70346.1 - 0.17 11.8 10.9 0.26 11.2 6.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 S4 PF01479.25 RJW70347.1 - 5.6e-08 32.4 0.5 1.5e-07 31.0 0.5 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 RJW70347.1 - 8.2e-07 29.8 0.5 1.7e-06 28.9 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain ECH_1 PF00378.20 RJW70350.1 - 8.9e-28 97.3 0.0 1.1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RJW70350.1 - 3.3e-13 49.8 0.0 1.8e-12 47.4 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase HCO3_cotransp PF00955.21 RJW70352.1 - 1.8e-71 241.5 25.1 2.9e-39 135.3 7.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.13 RJW70352.1 - 3.3e-34 118.9 0.0 5.9e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 RJW70352.1 - 0.072 13.0 0.0 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Glyco_transf_8 PF01501.20 RJW70355.1 - 0.016 14.8 0.1 0.031 13.8 0.1 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 8 TNFR_c6 PF00020.18 RJW70357.1 - 2.2e-26 92.0 49.5 2.6e-09 37.3 8.8 4.5 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region TNFR_16_TM PF18422.1 RJW70357.1 - 2.4e-16 59.4 1.3 5.6e-16 58.2 1.3 1.6 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain Death PF00531.22 RJW70357.1 - 0.052 13.7 1.0 0.51 10.5 0.2 2.7 3 0 0 3 3 3 0 Death domain Orf78 PF06024.12 RJW70357.1 - 0.074 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) PrmC_N PF17827.1 RJW70357.1 - 0.13 12.9 0.0 0.52 10.9 0.0 2.0 1 0 0 1 1 1 0 PrmC N-terminal domain Ribosomal_S14 PF00253.21 RJW70357.1 - 1.6 8.5 8.8 8.3 6.3 0.0 3.4 3 0 0 3 3 3 0 Ribosomal protein S14p/S29e E3_UFM1_ligase PF09743.9 RJW70358.1 - 0.024 14.3 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 ZapB PF06005.12 RJW70359.1 - 0.008 16.6 0.2 0.38 11.2 0.1 2.5 2 0 0 2 2 2 1 Cell division protein ZapB Herpes_BLRF2 PF05812.12 RJW70359.1 - 0.014 15.5 0.1 0.072 13.2 0.1 2.2 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.21 RJW70359.1 - 0.059 13.5 2.4 3 8.0 1.3 2.7 2 0 0 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 RJW70359.1 - 0.065 13.3 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_U49 PF10463.9 RJW70359.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase U49 bZIP_2 PF07716.15 RJW70359.1 - 0.38 10.9 8.2 14 5.8 5.4 2.6 2 0 0 2 2 2 0 Basic region leucine zipper HALZ PF02183.18 RJW70359.1 - 2.3 8.5 6.0 14 6.0 2.7 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Polyketide_cyc PF03364.20 RJW70360.1 - 6.1e-12 45.9 0.0 7.5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport WW PF00397.26 RJW70365.1 - 1.4e-07 31.4 0.0 3.3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 WW domain Bax1-I PF01027.20 RJW70366.1 - 1.1e-16 61.3 18.2 1.2e-16 61.2 18.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 RJW70366.1 - 0.15 11.6 8.5 0.18 11.4 8.5 1.1 1 0 0 1 1 1 0 Bax inhibitor 1 like Peptidase_U4 PF03419.13 RJW70366.1 - 2.8 7.1 10.2 3.3 6.9 10.2 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA ABC2_membrane PF01061.24 RJW70366.1 - 7.7 5.9 22.4 6 6.2 10.9 2.0 1 1 1 2 2 2 0 ABC-2 type transporter Mito_carr PF00153.27 RJW70367.1 - 4e-28 97.2 0.1 1.7e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Transferrin PF00405.17 RJW70367.1 - 0.093 11.9 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Transferrin Tropomyosin PF00261.20 RJW70368.1 - 4e-91 304.6 78.5 2.7e-88 295.4 52.3 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 RJW70368.1 - 1.3e-37 129.1 65.5 2.1e-34 118.7 37.3 3.0 2 1 1 3 3 3 3 Tropomyosin like ERM PF00769.19 RJW70368.1 - 0.0026 17.6 21.0 0.0026 17.6 21.0 3.0 1 1 2 3 3 3 1 Ezrin/radixin/moesin family Vps53_N PF04100.12 RJW70368.1 - 0.0077 15.2 9.6 0.0077 15.2 9.6 2.6 1 1 2 3 3 3 2 Vps53-like, N-terminal MscS_porin PF12795.7 RJW70368.1 - 0.014 15.0 51.2 0.017 14.7 30.0 2.4 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Flagellin_C PF00700.21 RJW70368.1 - 0.034 14.5 11.6 0.039 14.3 2.5 3.9 3 1 1 4 4 4 0 Bacterial flagellin C-terminal helical region ALO PF04030.14 RJW70368.1 - 0.035 13.9 0.7 0.058 13.2 0.7 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase CALCOCO1 PF07888.11 RJW70368.1 - 0.036 12.9 51.6 0.051 12.5 51.6 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FPP PF05911.11 RJW70368.1 - 0.047 11.9 51.4 0.09 11.0 20.3 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Laminin_II PF06009.12 RJW70368.1 - 0.14 12.1 32.7 0.52 10.3 4.5 3.9 1 1 3 4 4 4 0 Laminin Domain II Fez1 PF06818.15 RJW70368.1 - 0.2 12.1 49.3 3.9 7.9 27.4 2.3 1 1 1 2 2 2 0 Fez1 ORF6C PF10552.9 RJW70368.1 - 0.31 11.1 0.1 0.31 11.1 0.1 4.1 3 1 1 4 4 4 0 ORF6C domain DUF3142 PF11340.8 RJW70368.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.6 2 2 2 4 4 4 0 Protein of unknown function (DUF3142) SH3BP5 PF05276.14 RJW70368.1 - 0.35 10.6 36.3 0.034 14.0 12.3 2.5 1 1 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) GAS PF13851.6 RJW70368.1 - 0.41 10.0 48.0 2.6 7.3 24.8 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 RJW70368.1 - 0.41 10.7 31.3 0.66 10.0 1.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 RJW70368.1 - 0.46 10.1 52.3 0.34 10.5 5.3 3.3 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 RJW70368.1 - 0.7 9.9 16.0 0.62 10.1 4.3 3.6 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uds1 PF15456.6 RJW70368.1 - 1.7 8.8 43.1 0.13 12.5 9.7 3.6 1 1 1 3 3 3 0 Up-regulated During Septation CC2-LZ PF16516.5 RJW70368.1 - 2 8.8 41.9 0.094 13.1 5.0 4.8 1 1 2 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator AAA_13 PF13166.6 RJW70368.1 - 2.1 6.9 43.8 1.7 7.2 23.7 2.2 1 1 0 2 2 2 0 AAA domain Golgin_A5 PF09787.9 RJW70368.1 - 2.1 7.7 54.6 0.26 10.7 18.7 2.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 BORCS7 PF16088.5 RJW70368.1 - 3 8.2 13.5 3.6 7.9 0.2 3.8 2 2 2 4 4 4 0 BLOC-1-related complex sub-unit 7 DUF16 PF01519.16 RJW70368.1 - 3.2 8.3 33.2 5.6 7.5 3.9 4.1 1 1 3 4 4 4 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 RJW70368.1 - 3.5 7.8 30.7 1.1 9.4 1.3 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MAD PF05557.13 RJW70368.1 - 4 5.7 55.2 0.071 11.5 23.1 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein EzrA PF06160.12 RJW70368.1 - 4.3 5.4 44.7 0.29 9.2 5.4 3.6 1 1 3 4 4 4 0 Septation ring formation regulator, EzrA DUF4472 PF14739.6 RJW70368.1 - 4.7 8.0 49.1 0.6 10.9 12.1 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DUF948 PF06103.11 RJW70368.1 - 5 7.5 15.1 36 4.7 2.1 4.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 RJW70368.1 - 5.1 7.6 15.0 15 6.2 0.4 4.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.18 RJW70368.1 - 5.1 7.9 18.7 0.27 11.9 7.9 3.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4407 PF14362.6 RJW70368.1 - 5.4 6.3 48.2 0.27 10.5 22.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 RJW70368.1 - 5.9 6.7 50.4 0.7 9.7 19.2 3.3 1 1 1 2 2 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 RJW70368.1 - 6.2 6.9 49.5 0.28 11.3 8.0 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding XhlA PF10779.9 RJW70368.1 - 7.2 6.9 40.5 0.78 10.0 2.0 5.4 4 1 1 5 5 5 0 Haemolysin XhlA HemX PF04375.14 RJW70368.1 - 8 5.6 44.0 1.3 8.2 6.4 3.0 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3573 PF12097.8 RJW70368.1 - 8.8 5.0 6.2 13 4.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) UPAR_LY6 PF00021.21 RJW70370.1 - 0.23 12.2 12.4 2.7 8.7 9.6 2.6 2 1 0 2 2 2 0 u-PAR/Ly-6 domain TRAM_LAG1_CLN8 PF03798.16 RJW70371.1 - 6.4e-30 104.4 25.9 1.2e-29 103.4 25.9 1.4 1 0 0 1 1 1 1 TLC domain MULE PF10551.9 RJW70372.1 - 1.6e-14 54.1 0.0 3.7e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Ig_3 PF13927.6 RJW70373.1 - 1.1e-32 112.4 24.9 2.2e-12 47.4 0.1 9.9 9 2 0 9 9 9 6 Immunoglobulin domain I-set PF07679.16 RJW70373.1 - 2.7e-28 97.8 0.1 1.3e-05 25.2 0.0 9.8 9 3 0 9 9 9 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW70373.1 - 1.7e-20 73.1 15.1 0.00049 20.4 0.0 9.9 9 1 0 9 9 9 4 Immunoglobulin domain ig PF00047.25 RJW70373.1 - 1.4e-17 63.6 10.7 1.5e-05 25.1 0.0 9.0 9 2 0 9 9 9 3 Immunoglobulin domain V-set PF07686.17 RJW70373.1 - 6.3e-10 39.2 10.7 0.53 10.5 0.0 8.5 7 2 0 7 7 7 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 RJW70373.1 - 3.2e-08 33.5 5.8 0.0072 16.4 0.0 6.2 7 0 0 7 7 7 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 RJW70373.1 - 0.0043 17.4 1.3 9 6.8 0.0 5.7 7 1 0 7 7 7 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 RJW70373.1 - 0.0045 16.8 2.1 0.081 12.7 0.0 3.7 4 1 1 5 5 5 1 Adenovirus E3 region protein CR1 V-set_CD47 PF08204.11 RJW70373.1 - 0.013 15.4 3.5 9.4 6.2 0.0 5.1 5 0 0 5 5 5 0 CD47 immunoglobulin-like domain fn3 PF00041.21 RJW70373.1 - 0.02 15.2 2.6 2.9 8.3 0.0 4.1 3 0 0 3 3 3 0 Fibronectin type III domain Ribosomal_L18 PF17135.4 RJW70375.1 - 6.5e-89 296.3 2.0 8e-89 296.0 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 RJW70375.1 - 0.07 13.8 0.1 0.23 12.2 0.1 1.9 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TatD_DNase PF01026.21 RJW70377.1 - 7.8e-37 127.0 0.0 1.2e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase RVT_1 PF00078.27 RJW70377.1 - 1.6e-29 103.1 0.0 2.6e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_19 PF00182.19 RJW70378.1 - 2e-39 135.9 2.3 2.2e-38 132.5 2.3 1.9 1 1 0 1 1 1 1 Chitinase class I LRR_8 PF13855.6 RJW70380.1 - 4.9e-16 58.2 0.2 5.4e-09 35.7 0.1 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RJW70380.1 - 1.4e-09 38.1 1.6 0.00015 22.1 0.3 2.4 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW70380.1 - 4e-05 23.6 2.7 4 8.4 0.1 4.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 RJW70380.1 - 0.00012 21.9 1.8 1.1 9.5 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.6 RJW70380.1 - 0.0019 17.8 0.1 0.002 17.6 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.6 RJW70380.1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.3 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Tropomyosin PF00261.20 RJW70382.1 - 1e-41 142.8 44.9 1.3e-41 142.5 44.9 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 RJW70382.1 - 4.5e-10 39.8 43.0 1.1e-09 38.6 14.6 2.8 1 1 1 2 2 2 1 Tropomyosin like DUF745 PF05335.13 RJW70382.1 - 0.00098 18.9 26.5 0.029 14.1 6.9 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF745) Laminin_II PF06009.12 RJW70382.1 - 0.0014 18.6 23.5 0.0067 16.4 8.7 3.3 1 1 2 3 3 3 2 Laminin Domain II HOOK PF05622.12 RJW70382.1 - 0.015 13.5 33.4 0.57 8.3 33.1 2.6 1 1 0 1 1 1 0 HOOK protein Fib_alpha PF08702.10 RJW70382.1 - 0.016 15.4 21.1 0.58 10.3 6.0 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Mod_r PF07200.13 RJW70382.1 - 0.016 15.3 25.3 0.16 12.1 1.3 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein EzrA PF06160.12 RJW70382.1 - 0.02 13.1 27.9 0.043 12.0 7.5 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 RJW70382.1 - 0.033 14.2 19.3 0.043 13.8 6.2 3.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) GvpH PF05455.11 RJW70382.1 - 0.037 14.1 1.6 0.047 13.8 0.5 1.7 1 1 0 1 1 1 0 GvpH DUF16 PF01519.16 RJW70382.1 - 0.049 14.1 22.7 1.9 9.0 6.1 3.7 1 1 3 4 4 4 0 Protein of unknown function DUF16 Filament PF00038.21 RJW70382.1 - 0.067 12.8 31.5 0.15 11.6 2.7 2.8 1 1 0 2 2 2 0 Intermediate filament protein ATG16 PF08614.11 RJW70382.1 - 0.09 13.0 39.5 0.16 12.2 21.2 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 RJW70382.1 - 0.31 11.4 28.4 0.11 12.9 15.9 2.8 1 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Laminin_I PF06008.14 RJW70382.1 - 0.47 10.1 28.4 0.51 10.0 8.2 2.5 1 1 1 2 2 2 0 Laminin Domain I CENP-F_leu_zip PF10473.9 RJW70382.1 - 0.75 9.8 40.4 0.64 10.0 20.3 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 RJW70382.1 - 0.79 10.1 24.9 0.34 11.2 6.4 3.9 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC144C PF14915.6 RJW70382.1 - 0.81 8.7 31.4 6.9 5.7 31.4 2.1 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region BST2 PF16716.5 RJW70382.1 - 0.91 10.2 24.9 0.37 11.4 9.2 3.3 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 Flagellin_N PF00669.20 RJW70382.1 - 1 9.5 10.8 0.08 13.0 3.5 2.7 2 2 1 3 3 3 0 Bacterial flagellin N-terminal helical region Syntaxin-6_N PF09177.11 RJW70382.1 - 1.1 9.8 27.6 1.3 9.6 9.3 3.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Golgin_A5 PF09787.9 RJW70382.1 - 1.2 8.6 32.3 0.6 9.5 5.5 2.5 1 1 0 2 2 2 0 Golgin subfamily A member 5 DUF3584 PF12128.8 RJW70382.1 - 1.2 6.6 31.1 1.2 6.5 7.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4763 PF15960.5 RJW70382.1 - 1.3 8.2 17.1 0.1 11.9 3.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) XhlA PF10779.9 RJW70382.1 - 1.8 8.8 25.1 0.42 10.8 1.9 4.9 2 2 4 6 6 6 0 Haemolysin XhlA DUF4200 PF13863.6 RJW70382.1 - 2.2 8.7 38.0 23 5.4 10.5 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF4472 PF14739.6 RJW70382.1 - 2.2 9.1 28.0 0.21 12.3 9.6 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) CALCOCO1 PF07888.11 RJW70382.1 - 2.4 6.9 36.3 0.21 10.4 29.3 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Occludin_ELL PF07303.13 RJW70382.1 - 2.9 8.7 17.1 0.38 11.5 3.7 3.8 2 1 2 4 4 4 0 Occludin homology domain HemX PF04375.14 RJW70382.1 - 3 7.0 21.0 3 7.0 7.8 2.5 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase TMPIT PF07851.13 RJW70382.1 - 3 7.0 21.2 0.45 9.7 3.2 2.6 1 1 3 4 4 4 0 TMPIT-like protein Sec20 PF03908.13 RJW70382.1 - 3.1 7.8 6.6 3.4 7.6 0.2 3.4 1 1 3 4 4 4 0 Sec20 FPP PF05911.11 RJW70382.1 - 3.7 5.6 33.0 0.15 10.3 17.2 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF812 PF05667.11 RJW70382.1 - 3.8 6.3 36.7 0.47 9.3 9.0 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 RJW70382.1 - 5.2 5.6 28.6 3.7 6.1 25.6 2.0 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.12 RJW70382.1 - 6.5 7.3 9.1 1.1e+02 3.4 0.2 3.8 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 RJW70382.1 - 8.5 5.2 37.1 7.5 5.3 8.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein RhoGAP PF00620.27 RJW70384.1 - 3.3e-38 130.9 0.0 6e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PDZ_6 PF17820.1 RJW70384.1 - 6e-07 29.2 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW70384.1 - 5.9e-05 23.3 0.0 0.00018 21.8 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW70384.1 - 0.001 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW70387.1 - 2.2e-59 197.8 3.6 7.8e-16 58.2 0.1 4.9 5 0 0 5 5 5 4 PDZ domain PDZ_6 PF17820.1 RJW70387.1 - 7e-33 112.3 6.7 8e-09 35.2 0.2 4.9 5 0 0 5 5 5 4 PDZ domain PDZ_2 PF13180.6 RJW70387.1 - 5.9e-19 68.2 1.1 0.00022 21.5 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_4 PF17816.1 RJW70387.1 - 0.0028 18.0 0.0 23 5.5 0.0 4.1 4 0 0 4 4 4 1 PDZ domain FLgD_tudor PF13861.6 RJW70387.1 - 0.26 11.5 2.7 0.9 9.8 0.1 2.9 2 2 0 2 2 2 0 FlgD Tudor-like domain zf-A20 PF01754.16 RJW70388.1 - 3.6e-11 42.8 6.6 1.5e-10 40.8 6.6 2.2 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 RJW70388.1 - 1.2e-09 38.1 6.6 1.2e-09 38.1 6.6 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger Peptidase_A17 PF05380.13 RJW70389.1 - 3e-54 183.4 0.0 7e-54 182.2 0.0 1.7 1 0 0 1 1 1 1 Pao retrotransposon peptidase RT_RNaseH PF17917.1 RJW70389.1 - 3.4e-26 91.6 0.1 2.9e-25 88.6 0.1 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW70389.1 - 7.4e-25 86.9 0.0 1.2e-22 79.8 0.0 2.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW70389.1 - 1.6e-23 83.4 0.0 6.3e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RJW70389.1 - 4.4e-08 33.1 2.2 1.1e-07 31.8 2.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1759 PF03564.15 RJW70389.1 - 6.7e-07 29.4 0.0 1.1e-05 25.4 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) rve PF00665.26 RJW70389.1 - 8.9e-07 29.1 0.0 2.5e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 RJW70389.1 - 1.9e-06 28.4 0.9 0.00068 20.2 0.2 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 RJW70389.1 - 3e-06 27.7 0.1 0.032 14.8 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.20 RJW70389.1 - 7.7e-05 22.9 0.4 0.048 14.0 0.0 3.2 3 0 0 3 3 2 1 Retroviral aspartyl protease DNA_pol_viral_C PF00336.18 RJW70389.1 - 0.038 13.4 0.9 0.28 10.6 0.2 2.4 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain DUF1758 PF05585.12 RJW70389.1 - 0.068 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-C2H2 PF00096.26 RJW70391.1 - 1.3e-19 69.4 40.6 3.1e-05 24.2 2.9 5.9 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW70391.1 - 5.7e-13 48.5 42.8 0.0088 16.8 1.1 5.9 6 0 0 6 6 5 5 C2H2-type zinc finger zf-met PF12874.7 RJW70391.1 - 4.2e-11 42.9 18.5 0.025 14.9 0.0 5.4 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 RJW70391.1 - 6e-08 32.8 32.7 0.061 13.8 0.4 6.9 6 1 0 6 6 6 4 Zinc-finger double domain zf-Di19 PF05605.12 RJW70391.1 - 4.9e-06 26.7 22.7 0.0029 17.9 1.5 3.5 2 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 RJW70391.1 - 0.00024 20.9 11.6 1.6 8.6 0.1 5.1 2 2 3 5 5 5 2 C2H2 type zinc-finger (1 copy) LUC7 PF03194.15 RJW70391.1 - 0.0005 19.8 0.0 0.00078 19.2 0.0 1.3 1 0 0 1 1 1 1 LUC7 N_terminus zf-C2H2_2 PF12756.7 RJW70391.1 - 0.002 18.4 21.1 1.6 9.1 1.3 4.2 1 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 RJW70391.1 - 0.0022 18.0 38.0 0.1 12.7 0.6 5.6 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW70391.1 - 0.0069 16.6 0.1 0.0069 16.6 0.1 5.2 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 RJW70391.1 - 0.026 14.1 8.6 1.9 8.2 0.2 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger PHF5 PF03660.14 RJW70391.1 - 0.06 13.5 5.7 1.5 9.0 0.0 3.0 2 1 0 2 2 2 0 PHF5-like protein Zn-ribbon_8 PF09723.10 RJW70391.1 - 0.083 13.0 12.2 7.1 6.8 1.0 4.6 3 1 1 4 4 4 0 Zinc ribbon domain Zn-C2H2_12 PF18112.1 RJW70391.1 - 0.51 10.9 7.2 16 6.0 0.2 4.2 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain DUF2256 PF10013.9 RJW70391.1 - 0.72 10.0 13.3 7.3 6.8 0.0 4.8 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) YdjO PF14169.6 RJW70391.1 - 0.78 9.5 7.8 2.9 7.7 0.5 3.9 4 1 0 4 4 4 0 Cold-inducible protein YdjO zinc-ribbons_6 PF07191.12 RJW70391.1 - 1.2 9.1 16.2 6.9 6.7 0.1 4.4 2 2 1 3 3 3 0 zinc-ribbons FYVE PF01363.21 RJW70391.1 - 3.1 8.0 26.4 8.6 6.6 14.6 4.1 3 1 0 3 3 3 0 FYVE zinc finger zf-C2H2_3rep PF18868.1 RJW70391.1 - 6.3 7.5 17.7 13 6.5 6.0 4.4 2 1 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats Guanylate_kin PF00625.21 RJW70392.1 - 1.2e-27 96.7 0.5 1.7e-26 93.0 0.0 2.5 2 1 0 2 2 2 1 Guanylate kinase IQ PF00612.27 RJW70394.1 - 3.1e-32 107.3 16.1 1.4e-06 27.6 0.1 5.3 5 0 0 5 5 5 5 IQ calmodulin-binding motif TetR_C_6 PF13977.6 RJW70394.1 - 0.0041 17.3 0.3 25 5.1 0.0 4.1 3 1 1 4 4 4 2 BetI-type transcriptional repressor, C-terminal MFS_1 PF07690.16 RJW70395.1 - 2.8e-11 43.0 39.0 7.2e-11 41.6 32.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM221 PF14753.6 RJW70396.1 - 9.2e-77 257.1 8.4 1.2e-76 256.7 8.4 1.1 1 0 0 1 1 1 1 Protein FAM221A/B IQ PF00612.27 RJW70398.1 - 3.1e-32 107.3 16.1 1.4e-06 27.6 0.1 5.3 5 0 0 5 5 5 5 IQ calmodulin-binding motif TetR_C_6 PF13977.6 RJW70398.1 - 0.0039 17.4 0.3 25 5.1 0.0 4.1 3 1 1 4 4 4 2 BetI-type transcriptional repressor, C-terminal Atrophin-1 PF03154.15 RJW70401.1 - 0.021 13.1 1.0 0.022 13.1 1.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family zf-HC5HC2H_2 PF13832.6 RJW70402.1 - 0.034 14.3 0.5 0.062 13.5 0.0 1.6 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-TRAF PF02176.18 RJW70404.1 - 1.2e-17 64.4 33.6 3.3e-11 43.7 7.6 4.0 3 1 1 4 4 3 2 TRAF-type zinc finger Sina PF03145.16 RJW70404.1 - 3.9e-08 33.5 15.3 0.001 19.0 2.1 3.0 1 1 2 3 3 3 2 Seven in absentia protein family zf-C3HC4 PF00097.25 RJW70404.1 - 0.00031 20.5 5.6 0.00031 20.5 5.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW70404.1 - 0.00037 20.3 7.3 0.00037 20.3 7.3 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW70404.1 - 0.00051 19.8 6.0 0.00051 19.8 6.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 RJW70404.1 - 0.0039 17.0 2.3 0.0039 17.0 2.3 2.6 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-TRAF_2 PF15965.5 RJW70404.1 - 0.033 14.6 25.5 1.4 9.5 4.8 3.7 1 1 2 3 3 3 0 TRAF-like zinc-finger DUF4470 PF14737.6 RJW70404.1 - 0.048 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) Presenilin PF01080.17 RJW70404.1 - 0.42 9.3 8.4 0.56 8.9 8.4 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 RJW70404.1 - 2.8 6.5 7.9 4 6.0 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TRAF6_Z2 PF18048.1 RJW70404.1 - 2.8 8.1 7.3 16 5.7 0.0 3.1 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Zip PF02535.22 RJW70404.1 - 4.6 6.4 8.1 6.7 5.8 8.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Mis12 PF05859.12 RJW70405.1 - 6.9e-06 26.2 0.8 1.8e-05 24.8 0.7 1.7 1 1 0 1 1 1 1 Mis12 protein DHR10 PF18595.1 RJW70405.1 - 0.0029 17.7 1.6 0.019 15.0 0.9 2.0 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain FTA4 PF13093.6 RJW70405.1 - 0.1 12.5 1.3 0.2 11.6 0.3 1.6 1 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TMEM173 PF15009.6 RJW70408.1 - 0.065 12.4 1.2 9.1 5.3 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 173 Band_7 PF01145.25 RJW70409.1 - 2.1e-20 73.5 0.0 2.1e-20 73.5 0.0 3.3 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 RJW70409.1 - 4.1e-08 33.4 9.4 4.1e-08 33.4 9.4 4.4 2 2 2 4 4 4 3 Flotillin DUF1223 PF06764.11 RJW70409.1 - 0.49 10.4 7.0 0.39 10.7 4.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1223) Hid1 PF12722.7 RJW70409.1 - 5.3 5.0 6.5 7.3 4.6 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Usp PF00582.26 RJW70411.1 - 1.9e-27 96.5 0.0 2.6e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family ABC_tran PF00005.27 RJW70412.1 - 5.8e-54 182.3 0.0 6.9e-29 101.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RJW70412.1 - 6.1e-53 180.1 51.3 5.1e-37 127.8 15.7 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 RJW70412.1 - 4.6e-22 79.2 0.1 1.2e-08 35.1 0.1 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RJW70412.1 - 1.4e-05 24.6 0.2 0.041 13.3 0.0 2.9 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RJW70412.1 - 3.9e-05 24.2 5.5 0.0056 17.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 RJW70412.1 - 0.00013 21.6 0.7 0.0066 16.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RJW70412.1 - 0.00023 21.1 0.0 0.0041 17.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 RJW70412.1 - 0.00085 19.7 0.0 0.47 10.8 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 RJW70412.1 - 0.0022 18.1 0.1 0.93 9.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 RJW70412.1 - 0.0023 17.7 0.0 0.14 11.8 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain DUF4162 PF13732.6 RJW70412.1 - 0.012 16.4 0.0 0.59 10.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) TMEM43 PF07787.12 RJW70412.1 - 0.029 13.8 2.7 0.059 12.7 2.7 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 Zeta_toxin PF06414.12 RJW70412.1 - 0.051 12.9 0.0 8.6 5.6 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_33 PF13671.6 RJW70412.1 - 0.065 13.4 0.3 13 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 RJW70412.1 - 0.081 13.2 0.0 38 4.6 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 RJW70412.1 - 0.1 12.2 1.2 8 6.0 0.3 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 RJW70412.1 - 0.13 12.5 0.0 16 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RJW70412.1 - 0.24 11.1 0.0 9.9 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-C4 PF00105.18 RJW70415.1 - 7e-43 144.9 31.9 4.5e-23 81.5 11.6 2.4 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) ABC_tran PF00005.27 RJW70416.1 - 1.8e-52 177.5 0.0 4.2e-26 92.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RJW70416.1 - 5.3e-37 127.7 56.0 3.3e-29 102.1 26.2 2.5 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 RJW70416.1 - 1.3e-18 67.8 5.6 6.7e-06 26.1 0.0 4.6 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RJW70416.1 - 0.00073 20.1 3.5 0.013 16.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RJW70416.1 - 0.00079 19.1 1.8 0.14 11.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.22 RJW70416.1 - 0.0023 17.6 0.7 0.25 11.0 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 RJW70416.1 - 0.0063 16.4 0.1 0.23 11.3 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_15 PF13175.6 RJW70416.1 - 0.011 15.4 0.2 0.12 12.1 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 RJW70416.1 - 0.046 13.0 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.19 RJW70416.1 - 0.064 12.7 0.0 4.9 6.5 0.0 3.2 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RJW70416.1 - 0.1 13.0 0.1 8.3 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 RJW70416.1 - 0.12 12.4 0.1 10 6.2 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DLIC PF05783.11 RJW70416.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_13 PF13166.6 RJW70416.1 - 0.16 10.6 0.0 0.16 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RJW70416.1 - 0.16 11.7 0.1 0.98 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain LEAP-2 PF07359.11 RJW70417.1 - 0.087 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) GlcNAc_2-epim PF07221.11 RJW70418.1 - 0.011 15.0 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Radical_SAM_C PF16199.5 RJW70418.1 - 0.032 14.2 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Radical_SAM C-terminal domain UPAR_LY6 PF00021.21 RJW70420.1 - 0.29 11.9 8.2 0.56 11.0 8.2 1.5 1 1 0 1 1 1 0 u-PAR/Ly-6 domain NCD3G PF07562.14 RJW70420.1 - 0.88 9.6 13.9 0.071 13.1 3.2 2.5 2 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR T-box_assoc PF16176.5 RJW70421.1 - 0.9 9.6 7.7 0.5 10.4 1.4 3.1 2 2 1 3 3 3 0 T-box transcription factor-associated KLRAQ PF10205.9 RJW70422.1 - 0.012 15.9 5.6 0.025 14.8 5.6 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Troponin PF00992.20 RJW70422.1 - 0.017 15.4 3.9 0.029 14.7 3.9 1.3 1 0 0 1 1 1 0 Troponin Fungal_TACC PF12709.7 RJW70422.1 - 0.32 11.5 6.0 0.23 12.0 2.6 2.3 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins IFT20 PF14931.6 RJW70422.1 - 1.8 8.7 9.3 12 6.1 0.2 2.2 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 ZapB PF06005.12 RJW70422.1 - 4.7 7.7 11.7 0.1 13.0 2.3 2.4 2 1 1 3 3 3 0 Cell division protein ZapB Cwf_Cwc_15 PF04889.12 RJW70423.1 - 7.9e-22 78.2 0.3 9.7e-22 77.9 0.3 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein IP_trans PF02121.18 RJW70424.1 - 7.9e-97 323.7 0.0 1.2e-96 323.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF2505 PF10698.9 RJW70424.1 - 0.0022 18.1 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2505) DUF2559 PF10832.8 RJW70424.1 - 0.084 13.0 0.6 0.17 12.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) DUF937 PF06078.11 RJW70425.1 - 0.078 13.6 0.1 0.16 12.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Coatomer_E PF04733.14 RJW70426.1 - 2.9e-76 256.7 1.9 3.6e-76 256.4 1.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 RJW70426.1 - 2e-06 28.2 11.1 8.2e-05 23.0 0.5 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW70426.1 - 2.1e-06 27.9 5.9 3.3e-06 27.3 1.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW70426.1 - 2.9e-05 24.2 9.6 0.046 13.9 0.3 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 RJW70426.1 - 0.0002 21.4 0.5 0.34 11.0 0.1 2.9 2 1 0 2 2 2 2 Putative TPR-like repeat TPR_10 PF13374.6 RJW70426.1 - 0.0023 17.7 2.0 0.65 9.9 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW70426.1 - 0.019 15.0 5.1 0.45 10.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW70426.1 - 0.21 11.7 2.0 4.8 7.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW70426.1 - 0.56 11.0 4.2 5.6 7.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW70426.1 - 0.72 9.8 4.5 3.7 7.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RJW70426.1 - 1.5 9.9 6.7 12 7.0 0.0 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat Usp PF00582.26 RJW70429.1 - 2.1e-26 93.1 0.0 3.2e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family ETF PF01012.21 RJW70429.1 - 0.014 15.3 0.1 0.046 13.6 0.0 1.9 2 1 0 2 2 2 0 Electron transfer flavoprotein domain ATP-synt_ab PF00006.25 RJW70430.1 - 3.5e-69 232.7 0.0 5.8e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 RJW70430.1 - 4.5e-14 52.7 0.6 7.8e-14 52.0 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ICAM_N PF03921.14 RJW70431.1 - 0.026 14.2 0.5 0.041 13.6 0.5 1.3 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF1126 PF06565.12 RJW70435.1 - 4.3e-96 315.8 0.6 2.1e-35 120.7 0.0 3.8 3 1 0 3 3 3 3 DUF1126 PH-like domain PH PF00169.29 RJW70437.1 - 0.0076 16.7 0.0 0.028 14.9 0.0 2.1 1 0 0 1 1 1 1 PH domain GDI PF00996.18 RJW70438.1 - 0.18 10.3 0.0 0.18 10.3 0.0 1.0 1 0 0 1 1 1 0 GDP dissociation inhibitor DUF2258 PF10015.9 RJW70441.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) TRC8_N PF13705.6 RJW70442.1 - 1.3e-13 50.8 27.6 3e-12 46.2 0.9 3.8 3 1 0 3 3 3 2 TRC8 N-terminal domain zf-RING_2 PF13639.6 RJW70442.1 - 5.3e-09 36.3 8.1 5.3e-09 36.3 8.1 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RJW70442.1 - 7e-08 32.2 6.5 2.1e-07 30.6 6.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW70442.1 - 1.7e-06 28.2 7.4 5.5e-06 26.6 7.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RJW70442.1 - 6.4e-06 26.1 3.6 1.6e-05 24.8 3.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RJW70442.1 - 9.3e-06 25.4 4.9 3.7e-05 23.5 4.9 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW70442.1 - 1.4e-05 24.9 5.3 8.1e-05 22.5 4.6 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RJW70442.1 - 6.9e-05 22.6 3.6 0.00026 20.8 3.6 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RJW70442.1 - 0.00035 20.3 1.4 0.00035 20.3 1.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 RJW70442.1 - 0.0054 16.9 2.8 0.046 13.9 2.9 2.3 1 1 1 2 2 2 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 RJW70442.1 - 0.0076 15.9 3.7 0.0076 15.9 3.7 2.8 3 0 0 3 3 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RJW70442.1 - 0.0098 15.9 2.1 0.0098 15.9 2.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RJW70442.1 - 0.066 13.1 7.3 2.7 7.9 7.7 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 RJW70442.1 - 1.8 8.7 4.6 4.2 7.6 4.6 1.7 1 0 0 1 1 1 0 RING-variant domain Transglut_core PF01841.19 RJW70446.1 - 0.023 15.1 0.3 0.085 13.3 0.0 2.2 2 1 0 2 2 2 0 Transglutaminase-like superfamily DUF553 PF04473.12 RJW70446.1 - 0.042 13.4 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like domain HA2 PF04408.23 RJW70449.1 - 1.5e-17 63.8 3.2 3.3e-17 62.7 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RJW70449.1 - 8.6e-11 42.0 0.0 2e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RJW70449.1 - 1e-10 41.9 0.0 4.4e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RJW70449.1 - 1.3e-09 38.1 0.0 2.9e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RJW70449.1 - 7e-05 23.1 0.1 0.0004 20.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RJW70449.1 - 0.0002 21.2 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RJW70449.1 - 0.00099 19.5 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 RJW70449.1 - 0.004 16.5 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 RJW70449.1 - 0.012 14.7 0.6 0.041 12.9 0.6 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein EcoEI_R_C PF08463.10 RJW70449.1 - 0.024 14.7 1.0 0.066 13.3 1.0 1.7 1 0 0 1 1 1 0 EcoEI R protein C-terminal AAA_14 PF13173.6 RJW70449.1 - 0.05 13.6 0.0 2.4 8.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 RJW70449.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 RJW70449.1 - 0.17 11.9 2.7 2.1 8.3 0.4 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit T-box_assoc PF16176.5 RJW70450.1 - 0.00034 20.8 18.2 1.8 8.6 0.6 5.1 1 1 6 7 7 7 5 T-box transcription factor-associated RVT_1 PF00078.27 RJW70450.1 - 0.00036 20.1 0.0 0.00087 18.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RrnaAD PF00398.20 RJW70451.1 - 2.6e-60 203.7 0.0 3.2e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RJW70451.1 - 5.4e-10 39.8 0.0 1.3e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RJW70451.1 - 1.3e-06 29.0 0.0 3e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RJW70451.1 - 3.7e-06 26.6 0.0 5.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 RJW70451.1 - 1.3e-05 25.0 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RJW70451.1 - 1.4e-05 25.7 0.0 2.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RJW70451.1 - 2.1e-05 24.4 0.0 4.1e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 RJW70451.1 - 0.0002 21.0 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 RJW70451.1 - 0.00028 20.8 0.0 0.00059 19.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 RJW70451.1 - 0.00036 19.9 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 RJW70451.1 - 0.00039 20.1 0.0 0.00062 19.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Met_10 PF02475.16 RJW70451.1 - 0.00096 19.0 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.16 RJW70451.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase DREV PF05219.12 RJW70451.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_18 PF12847.7 RJW70451.1 - 0.002 18.1 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 RJW70451.1 - 0.0036 17.3 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RJW70451.1 - 0.0045 16.4 0.0 0.0064 15.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 RJW70451.1 - 0.0069 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 RJW70451.1 - 0.022 14.5 0.0 0.045 13.4 0.0 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 RJW70451.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_PK PF05891.12 RJW70451.1 - 0.065 12.7 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_28 PF02636.17 RJW70451.1 - 0.07 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase tRNA_U5-meth_tr PF05958.11 RJW70451.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase KH_1 PF00013.29 RJW70452.1 - 3.7e-28 97.2 0.3 5.8e-13 48.5 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 RJW70452.1 - 2.5e-06 27.2 0.2 0.061 13.2 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 RJW70452.1 - 0.011 15.8 0.9 0.72 10.0 0.1 2.3 2 0 0 2 2 2 0 NusA-like KH domain KH_4 PF13083.6 RJW70452.1 - 0.013 15.3 0.4 3.4 7.6 0.1 2.4 2 0 0 2 2 2 0 KH domain Meis_PKNOX_N PF16493.5 RJW70453.1 - 0.04 14.2 1.2 0.094 13.1 0.3 2.1 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 DUF4201 PF13870.6 RJW70453.1 - 0.083 12.6 21.3 0.014 15.2 11.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Methyltransf_11 PF08241.12 RJW70455.1 - 3.8e-12 46.7 0.0 1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW70455.1 - 5.3e-11 43.1 0.0 1.1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW70455.1 - 5.7e-05 23.0 0.0 8.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 RJW70455.1 - 6.4e-05 23.6 1.6 0.0001 23.0 1.6 1.2 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_12 PF08242.12 RJW70455.1 - 0.00011 22.8 0.0 0.00038 21.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RJW70455.1 - 0.00018 21.4 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 RJW70455.1 - 0.003 17.5 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain APC1_C PF18122.1 RJW70455.1 - 0.094 12.7 0.2 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain ATP-synt_D PF01813.17 RJW70457.1 - 3.3e-57 193.5 1.0 4.2e-57 193.2 1.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Vps54_N PF10475.9 RJW70457.1 - 0.019 14.2 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex ALG11_N PF15924.5 RJW70458.1 - 7.2e-53 179.7 0.2 1e-52 179.2 0.2 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 RJW70458.1 - 3.6e-22 78.7 0.0 5.5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RJW70458.1 - 1.6e-11 44.8 0.0 2.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 MAD PF05557.13 RJW70459.1 - 0.00061 18.3 17.1 0.00095 17.7 17.1 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF4201 PF13870.6 RJW70459.1 - 0.00089 19.0 15.6 0.0012 18.6 11.5 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Rootletin PF15035.6 RJW70459.1 - 0.029 14.4 11.9 0.06 13.4 11.9 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Med9 PF07544.13 RJW70459.1 - 0.08 13.0 8.9 0.16 12.1 7.6 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF724 PF05266.14 RJW70459.1 - 0.1 12.4 4.0 0.25 11.2 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Pox_MCEL PF03291.16 RJW70459.1 - 0.13 11.3 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 mRNA capping enzyme Hrs_helical PF12210.8 RJW70459.1 - 0.31 11.6 5.2 0.87 10.2 5.2 1.8 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate YabA PF06156.13 RJW70459.1 - 0.5 11.0 8.9 0.62 10.7 5.9 2.5 2 0 0 2 2 2 0 Initiation control protein YabA BRE1 PF08647.11 RJW70459.1 - 0.51 10.4 15.2 0.62 10.2 10.5 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 RJW70459.1 - 0.65 9.8 10.6 30 4.5 10.6 3.0 1 1 0 1 1 1 0 Septum formation initiator DUF4763 PF15960.5 RJW70459.1 - 0.89 8.8 17.8 0.34 10.2 15.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Fez1 PF06818.15 RJW70459.1 - 2.2 8.7 14.7 0.21 12.0 8.7 2.1 1 1 1 2 2 2 0 Fez1 PilO PF04350.13 RJW70459.1 - 3.3 7.9 9.4 1.2 9.3 2.4 3.1 2 1 1 3 3 3 0 Pilus assembly protein, PilO Csm1_N PF18504.1 RJW70459.1 - 4.5 7.7 10.0 2.4 8.6 3.9 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 RJW70459.1 - 9.7 5.0 19.1 0.95 8.3 14.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 RJW70459.1 - 9.8 6.2 22.5 5.9 6.9 19.2 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HAUS4 PF14735.6 RJW70462.1 - 7.7e-05 22.5 7.6 0.00012 21.9 7.6 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 TMF_TATA_bd PF12325.8 RJW70462.1 - 0.037 14.2 1.0 0.094 12.9 1.0 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Metal_resist PF13801.6 RJW70462.1 - 0.13 12.4 2.8 4.2 7.6 0.3 2.3 2 0 0 2 2 2 0 Heavy-metal resistance APG6_N PF17675.1 RJW70462.1 - 1.8 9.1 8.3 0.11 13.0 2.4 2.0 3 0 0 3 3 3 0 Apg6 coiled-coil region Kelch_1 PF01344.25 RJW70464.1 - 7.9e-14 51.0 0.7 5.4e-07 29.1 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 RJW70464.1 - 1.2e-11 44.5 1.5 0.00014 22.0 0.0 3.4 2 1 1 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RJW70464.1 - 2.6e-11 43.4 0.2 6.8e-06 26.2 0.0 3.1 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.6 RJW70464.1 - 4e-07 29.9 0.1 0.00041 20.3 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 RJW70464.1 - 2.3e-05 24.2 0.2 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 RJW70464.1 - 0.0093 15.9 2.1 0.73 9.9 0.1 2.9 3 1 1 4 4 4 2 Kelch motif Gcd10p PF04189.13 RJW70465.1 - 8.4e-40 136.7 0.0 1.6e-39 135.8 0.0 1.4 1 1 0 1 1 1 1 Gcd10p family ASCH PF04266.14 RJW70466.1 - 8.2e-12 45.7 0.0 2.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 RJW70466.1 - 9e-12 44.8 10.9 1.9e-11 43.8 10.9 1.6 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF1657 PF07870.11 RJW70466.1 - 0.083 12.8 0.5 0.37 10.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) FYRC PF05965.14 RJW70467.1 - 2.1e-23 82.3 0.0 5.1e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 RJW70467.1 - 1.5e-20 72.8 0.8 3.7e-20 71.5 0.8 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 RJW70467.1 - 4.5e-19 69.5 0.8 3.1e-18 66.7 0.6 2.5 2 1 0 2 2 2 1 SET domain zf-HC5HC2H_2 PF13832.6 RJW70467.1 - 6.5e-09 35.9 9.3 6.5e-09 35.9 9.3 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RJW70467.1 - 3.4e-07 30.4 6.7 3.4e-07 30.4 6.7 2.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain WD40 PF00400.32 RJW70468.1 - 1.7e-14 53.9 14.2 1.3e-05 25.8 0.1 7.0 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW70468.1 - 2.2e-10 40.7 0.3 7.2e-06 26.2 0.0 4.1 5 2 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 RJW70468.1 - 0.0047 16.8 0.2 0.71 9.9 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat RIC1 PF07064.13 RJW70469.1 - 2.3e-70 236.9 0.1 5.8e-70 235.6 0.1 1.6 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 RJW70469.1 - 9e-05 22.7 0.7 0.012 15.9 0.2 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CoA_trans PF01144.23 RJW70470.1 - 3.2e-105 350.3 1.4 7.5e-71 238.0 0.5 2.0 2 0 0 2 2 2 2 Coenzyme A transferase XRCC4 PF06632.12 RJW70471.1 - 2.1e-14 53.1 2.2 2.2e-14 53.1 2.2 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF1444 PF07285.11 RJW70471.1 - 0.0057 16.3 0.5 0.0074 15.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1444) Med28 PF11594.8 RJW70471.1 - 0.0089 16.1 1.0 0.013 15.6 1.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 28 Dymeclin PF09742.9 RJW70471.1 - 0.017 13.6 0.6 0.021 13.2 0.1 1.4 2 0 0 2 2 2 0 Dyggve-Melchior-Clausen syndrome protein RasGAP_C PF03836.15 RJW70471.1 - 0.022 14.9 0.9 0.031 14.4 0.9 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Peptidase_C12 PF01088.21 RJW70471.1 - 0.023 14.4 0.1 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 TSC22 PF01166.18 RJW70471.1 - 0.028 14.7 5.5 0.068 13.5 2.2 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 RJW70471.1 - 0.032 14.3 4.9 0.051 13.6 4.9 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 RJW70471.1 - 0.051 12.9 0.5 0.064 12.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S64 PF08192.11 RJW70471.1 - 0.052 12.0 0.3 0.06 11.8 0.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 IZUMO PF15005.6 RJW70471.1 - 0.072 13.6 1.5 0.11 13.1 1.5 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated TMF_TATA_bd PF12325.8 RJW70471.1 - 0.13 12.5 8.5 0.41 10.9 8.5 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fzo_mitofusin PF04799.13 RJW70471.1 - 0.16 11.5 2.4 6.7 6.2 0.8 2.1 1 1 1 2 2 2 0 fzo-like conserved region YabA PF06156.13 RJW70471.1 - 0.27 11.9 4.3 0.52 11.0 4.3 1.6 1 1 0 1 1 1 0 Initiation control protein YabA GrpE PF01025.19 RJW70471.1 - 0.28 10.8 5.3 2.6 7.7 5.6 2.0 1 1 1 2 2 2 0 GrpE DUF2452 PF10504.9 RJW70471.1 - 0.66 9.4 3.5 1.6 8.2 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2452) Kelch_5 PF13854.6 RJW70477.1 - 2.2e-21 75.4 7.7 1.2e-06 28.4 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 RJW70477.1 - 8e-19 67.5 16.7 4.4e-05 23.7 0.1 7.8 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RJW70477.1 - 9e-19 67.2 8.1 0.0055 16.7 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 RJW70477.1 - 1.2e-15 56.8 4.6 0.0036 16.9 0.1 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RJW70477.1 - 1.4e-15 56.9 12.5 0.00045 20.4 0.0 7.1 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 RJW70477.1 - 5.9e-10 38.7 12.6 0.00038 20.3 0.1 6.6 8 0 0 8 8 8 3 Kelch motif IL11 PF07400.11 RJW70479.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Interleukin 11 ADP_ribosyl_GH PF03747.14 RJW70481.1 - 7.5e-44 150.6 0.0 1e-43 150.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF1107 PF06526.12 RJW70482.1 - 0.045 13.7 0.0 13 5.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1107) BTB_3 PF16017.5 RJW70485.1 - 3.1e-44 149.4 0.0 7.3e-44 148.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 RJW70485.1 - 0.093 13.1 0.0 0.34 11.3 0.0 2.0 1 1 0 1 1 1 0 BTB/POZ domain Chromo PF00385.24 RJW70487.1 - 1.3e-13 50.6 2.0 2.2e-13 49.9 2.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 RJW70487.1 - 2.1e-10 40.1 0.0 6.1e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 CBX family C-terminal motif Acyl_transf_3 PF01757.22 RJW70489.1 - 1.4e-21 77.0 47.7 1.4e-21 77.0 47.7 1.5 2 0 0 2 2 2 1 Acyltransferase family DUF4477 PF14780.6 RJW70490.1 - 7.4e-07 29.0 4.1 1.4e-06 28.1 4.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) PDCD2_C PF04194.13 RJW70491.1 - 6.7e-18 65.4 4.6 1e-17 64.8 0.1 2.3 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-trcl PF13451.6 RJW70491.1 - 0.095 12.6 1.2 11 6.0 0.1 2.8 2 0 0 2 2 2 0 Probable zinc-ribbon domain Syntaxin-6_N PF09177.11 RJW70492.1 - 6.5e-26 90.8 4.7 1.1e-25 90.0 1.3 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 RJW70492.1 - 3.6e-06 26.9 0.8 1.2e-05 25.2 0.1 2.2 2 0 0 2 2 2 1 SNARE domain IFT57 PF10498.9 RJW70492.1 - 0.01 14.8 1.3 1.5 7.8 0.1 2.3 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 NleF_casp_inhib PF16809.5 RJW70492.1 - 0.013 15.4 1.3 0.02 14.8 0.1 1.8 2 0 0 2 2 2 0 NleF caspase inhibitor EzrA PF06160.12 RJW70492.1 - 0.036 12.3 1.6 1.1 7.3 0.1 2.4 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Noelin-1 PF12308.8 RJW70492.1 - 0.036 14.0 2.4 4.9 7.2 0.0 3.0 2 1 1 3 3 3 0 Neurogenesis glycoprotein ATG16 PF08614.11 RJW70492.1 - 0.043 14.1 0.6 0.043 14.1 0.6 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) LXG PF04740.12 RJW70492.1 - 0.059 13.1 3.5 1.6 8.4 0.2 2.4 2 1 0 2 2 2 0 LXG domain of WXG superfamily Syntaxin_2 PF14523.6 RJW70492.1 - 0.17 12.3 5.0 5.7 7.4 0.6 2.4 2 1 0 2 2 2 0 Syntaxin-like protein DUF948 PF06103.11 RJW70492.1 - 0.2 11.9 2.0 34 4.8 0.1 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 RJW70492.1 - 0.72 9.9 4.6 8.7 6.4 0.2 2.4 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 RJW70492.1 - 0.88 10.1 5.7 21 5.7 0.2 3.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Muted PF14942.6 RJW70492.1 - 1 9.7 4.3 4.5 7.6 0.6 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein CorA PF01544.18 RJW70492.1 - 5.2 6.3 10.9 0.099 11.9 0.8 2.4 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DHR10 PF18595.1 RJW70492.1 - 6.6 6.8 8.8 4.3 7.4 1.9 2.8 2 2 0 2 2 2 0 Designed helical repeat protein 10 domain AsnC_trans_reg2 PF17805.1 RJW70497.1 - 0.075 13.2 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 AsnC-like ligand binding domain Cupin_8 PF13621.6 RJW70498.1 - 2.1e-31 109.6 0.1 4.3e-31 108.5 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 RJW70498.1 - 2.6e-09 37.0 0.0 8.4e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 RJW70498.1 - 2.1e-06 28.2 0.2 3.7e-06 27.3 0.2 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase OTU PF02338.19 RJW70498.1 - 3e-05 24.5 0.0 5.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Cupin_2 PF07883.11 RJW70498.1 - 0.017 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Cupin_6 PF12852.7 RJW70498.1 - 0.042 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_1 PF00190.22 RJW70498.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin LRR_8 PF13855.6 RJW70503.1 - 1.2e-62 207.5 73.5 3e-11 42.9 2.9 6.5 1 1 9 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 RJW70503.1 - 6.8e-31 105.8 48.9 4.2e-05 23.8 1.2 9.1 2 2 11 13 13 13 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW70503.1 - 7.1e-12 44.1 42.6 1.2 9.9 0.2 12.9 12 2 2 14 14 14 7 Leucine Rich Repeat LRR_9 PF14580.6 RJW70503.1 - 3.8e-10 39.5 21.3 0.0061 16.1 0.1 5.3 1 1 5 6 6 6 5 Leucine-rich repeat LRR_6 PF13516.6 RJW70503.1 - 0.00012 21.9 51.8 0.25 11.5 0.0 12.9 14 0 0 14 14 14 5 Leucine Rich repeat SH3_9 PF14604.6 RJW70504.1 - 3.6e-16 58.7 0.3 6.5e-16 57.9 0.3 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RJW70504.1 - 8.8e-15 54.1 1.4 1.2e-14 53.6 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 RJW70504.1 - 2.7e-11 43.0 0.0 5.2e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Cofilin_ADF PF00241.20 RJW70504.1 - 7.4e-11 41.9 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.32 RJW70505.1 - 3.6e-15 56.1 7.9 6.6e-05 23.6 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW70505.1 - 0.00023 21.4 0.1 0.038 14.3 0.1 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Myc-LZ PF02344.15 RJW70505.1 - 0.056 13.5 0.2 0.056 13.5 0.2 2.9 3 0 0 3 3 3 0 Myc leucine zipper domain Glyco_hydro_35 PF01301.19 RJW70506.1 - 1e-99 334.1 0.0 1.4e-99 333.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 RJW70506.1 - 4.3e-06 26.3 0.0 8.4e-05 22.1 0.0 2.1 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 RJW70506.1 - 1.1 9.8 3.7 12 6.5 0.0 3.1 3 0 0 3 3 3 0 Beta-galactosidase jelly roll domain zf-RING_5 PF14634.6 RJW70507.1 - 0.00031 20.6 9.1 0.00074 19.4 9.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain PRKG1_interact PF15898.5 RJW70507.1 - 0.0045 17.9 7.1 0.12 13.2 3.0 2.4 1 1 1 2 2 2 2 cGMP-dependent protein kinase interacting domain CCCAP PF15964.5 RJW70507.1 - 0.0071 14.7 4.5 0.01 14.2 4.5 1.1 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family DMPK_coil PF08826.10 RJW70507.1 - 0.0077 16.3 3.2 0.018 15.1 3.2 1.7 1 0 0 1 1 1 1 DMPK coiled coil domain like SPACA7 PF15307.6 RJW70507.1 - 0.082 13.2 0.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 DUF1664 PF07889.12 RJW70507.1 - 0.083 12.9 1.6 0.17 12.0 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 RJW70507.1 - 0.091 13.3 7.2 0.14 12.6 7.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 RJW70507.1 - 0.17 12.2 2.9 0.33 11.2 2.9 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Prok-RING_4 PF14447.6 RJW70507.1 - 0.23 11.3 8.1 0.93 9.4 8.1 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RJW70507.1 - 0.62 10.2 4.3 1.5 8.9 4.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.20 RJW70507.1 - 1 9.2 6.8 2.2 8.1 6.8 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-CCCH PF00642.24 RJW70509.1 - 1.6e-07 31.0 23.4 2.2e-06 27.4 1.5 4.4 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RJW70509.1 - 0.00029 20.8 2.0 0.00029 20.8 2.0 4.0 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 RJW70509.1 - 0.00067 19.4 21.3 0.00067 19.4 0.9 4.1 4 0 0 4 4 4 2 CCCH-type zinc finger Torus PF16131.5 RJW70509.1 - 0.47 11.2 14.4 0.72 10.6 1.5 3.3 1 1 1 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 RJW70509.1 - 1.6 9.0 10.6 0.62 10.3 5.1 2.5 1 1 1 2 2 2 0 Zinc-finger containing family RVT_1 PF00078.27 RJW70511.1 - 6.5e-41 140.3 0.0 1e-40 139.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) cNMP_binding PF00027.29 RJW70514.1 - 9.5e-18 64.1 0.0 1.7e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RJW70514.1 - 1.9e-13 50.2 4.8 2.9e-13 49.6 4.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW70514.1 - 0.14 12.1 7.5 0.061 13.3 4.6 1.9 2 0 0 2 2 2 0 Ion channel LRR_8 PF13855.6 RJW70515.1 - 3e-14 52.5 4.7 3.5e-13 49.1 1.3 3.4 2 1 0 3 3 3 1 Leucine rich repeat Ig_3 PF13927.6 RJW70515.1 - 0.016 15.8 0.2 0.065 13.8 0.2 2.2 1 0 0 1 1 1 0 Immunoglobulin domain LRR_4 PF12799.7 RJW70515.1 - 0.026 15.0 6.2 0.057 13.9 0.8 3.7 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW70515.1 - 0.048 14.2 7.5 0.42 11.3 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich Repeat I-set PF07679.16 RJW70515.1 - 0.17 12.0 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin I-set domain LRR_6 PF13516.6 RJW70515.1 - 0.34 11.1 4.2 7.6 6.9 0.0 4.2 4 1 1 5 5 5 0 Leucine Rich repeat GLE1 PF07817.13 RJW70516.1 - 2.4e-42 144.9 0.0 3.1e-41 141.3 0.0 2.2 1 1 0 1 1 1 1 GLE1-like protein AAA_25 PF13481.6 RJW70516.1 - 0.053 13.1 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain MutL_C PF08676.11 RJW70517.1 - 8e-07 28.9 0.0 9.3e-05 22.2 0.0 2.5 2 1 0 2 2 2 2 MutL C terminal dimerisation domain DUF592 PF04574.13 RJW70517.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Hint PF01079.20 RJW70518.1 - 1e-37 129.8 0.0 1.7e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Hint module HH_signal PF01085.18 RJW70518.1 - 2.1e-12 47.0 0.3 2.4e-07 30.5 0.1 2.4 2 0 0 2 2 2 2 Hedgehog amino-terminal signalling domain Hint_2 PF13403.6 RJW70518.1 - 0.00097 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 Hint domain zf-C2H2 PF00096.26 RJW70519.1 - 5.1e-09 36.1 23.6 0.0085 16.5 3.2 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW70519.1 - 1.1e-08 35.1 17.4 2.1e-06 27.9 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double domain GAGA PF09237.11 RJW70519.1 - 0.00013 21.7 0.3 0.0077 16.0 0.1 2.8 2 0 0 2 2 2 1 GAGA factor zf-met PF12874.7 RJW70519.1 - 0.00028 21.2 15.0 0.16 12.4 0.4 3.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RJW70519.1 - 0.00058 20.1 8.1 0.0023 18.2 3.8 2.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 RJW70519.1 - 0.0042 16.8 4.3 0.0042 16.8 4.3 3.6 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RJW70519.1 - 0.015 16.1 29.1 0.09 13.7 3.0 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger Vps36-NZF-N PF16988.5 RJW70519.1 - 0.1 12.0 1.1 1.6 8.2 0.1 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Endonuclease_7 PF02945.15 RJW70519.1 - 0.12 12.3 2.0 0.35 10.8 2.0 1.8 1 0 0 1 1 1 0 Recombination endonuclease VII zf-C2H2_2 PF12756.7 RJW70519.1 - 0.25 11.7 9.7 24 5.4 0.5 3.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 RJW70519.1 - 0.73 9.8 5.3 4.6 7.2 2.5 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrsD PF12013.8 RJW70519.1 - 3.3 8.2 14.7 2 8.9 0.4 4.1 4 1 1 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-BED PF02892.15 RJW70519.1 - 3.8 7.6 13.8 0.33 11.0 0.1 3.7 2 1 1 3 3 3 0 BED zinc finger Rpr2 PF04032.16 RJW70519.1 - 7.9 6.8 10.7 75 3.7 7.0 3.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain SNF PF00209.18 RJW70521.1 - 1.1e-206 687.6 38.0 1.4e-206 687.3 38.0 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family WWE PF02825.20 RJW70523.1 - 0.075 13.6 0.0 0.32 11.6 0.0 2.0 2 0 0 2 2 2 0 WWE domain Perilipin PF03036.16 RJW70524.1 - 0.0028 16.7 0.6 0.0028 16.7 0.6 2.0 1 1 1 2 2 2 1 Perilipin family HsbA PF12296.8 RJW70524.1 - 0.014 15.8 0.1 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Sec1 PF00995.23 RJW70526.1 - 1.4e-78 265.6 0.0 1.7e-78 265.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Ribosomal_S9 PF00380.19 RJW70528.1 - 7.1e-30 104.0 0.0 8.2e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Sugar_tr PF00083.24 RJW70530.1 - 1.8e-99 333.7 25.7 9.6e-57 192.8 6.0 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 RJW70530.1 - 7.3e-25 87.6 27.0 3.6e-24 85.4 14.3 2.5 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RJW70530.1 - 8.9e-05 21.1 2.5 0.00017 20.1 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RVT_1 PF00078.27 RJW70530.1 - 0.00017 21.2 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PSI_integrin PF17205.3 RJW70530.1 - 4.2 7.2 11.7 0.27 11.0 5.1 2.6 3 0 0 3 3 3 0 Integrin plexin domain DHC_N1 PF08385.12 RJW70532.1 - 1.1e-126 423.8 7.3 1.1e-126 423.8 7.3 5.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RJW70532.1 - 9.1e-119 396.2 11.9 2.1e-116 388.5 0.0 6.0 5 1 0 5 5 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW70532.1 - 1.4e-113 380.0 15.5 1.4e-113 380.0 15.5 5.1 5 1 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 RJW70532.1 - 2.7e-73 245.8 7.4 4.7e-73 245.0 0.0 4.4 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 RJW70532.1 - 1.3e-67 227.9 0.0 5.1e-67 225.9 0.0 2.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RJW70532.1 - 1.2e-45 155.2 0.1 2e-39 135.0 0.0 5.2 5 0 0 5 5 5 2 P-loop containing dynein motor region Dynein_C PF18199.1 RJW70532.1 - 3.2e-44 151.4 0.0 3.2e-44 151.4 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RJW70532.1 - 9.8e-40 136.0 0.0 5.7e-39 133.6 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 RJW70532.1 - 4.3e-35 121.4 11.4 7.7e-35 120.5 11.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RJW70532.1 - 4.5e-32 110.6 0.0 5.9e-31 107.0 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RJW70532.1 - 1.7e-29 102.6 0.0 1.6e-12 47.6 0.0 6.1 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RJW70532.1 - 6.8e-20 71.5 0.0 2.7e-19 69.5 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 RJW70532.1 - 5.4e-14 52.6 7.6 0.039 14.2 0.0 7.2 7 0 0 7 7 6 4 AAA domain AAA PF00004.29 RJW70532.1 - 3.4e-13 50.2 0.0 0.011 16.2 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW70532.1 - 8.9e-11 42.5 1.4 1.8 8.9 0.0 8.2 7 0 0 7 7 6 1 AAA ATPase domain AAA_33 PF13671.6 RJW70532.1 - 2.6e-10 40.6 0.2 0.056 13.6 0.0 6.1 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.6 RJW70532.1 - 1.4e-08 35.3 0.0 0.53 10.8 0.0 5.5 4 0 0 4 4 4 2 AAA domain Mg_chelatase PF01078.21 RJW70532.1 - 3.8e-06 26.4 3.0 0.073 12.4 0.0 3.9 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 RJW70532.1 - 6e-05 22.8 0.3 7.8 6.2 0.0 4.6 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 RJW70532.1 - 6.3e-05 22.2 0.0 0.078 12.0 0.0 3.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 RJW70532.1 - 9.4e-05 22.6 0.0 0.00057 20.1 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_29 PF13555.6 RJW70532.1 - 0.00027 20.6 0.0 3.2 7.5 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_24 PF13479.6 RJW70532.1 - 0.00097 18.9 1.8 30 4.2 0.0 5.2 5 0 0 5 5 5 0 AAA domain FtsK_SpoIIIE PF01580.18 RJW70532.1 - 0.0025 17.2 0.0 8.8 5.6 0.0 3.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 RJW70532.1 - 0.0029 18.0 0.0 4.1 7.8 0.0 4.1 4 0 0 4 4 4 1 RNA helicase Rad17 PF03215.15 RJW70532.1 - 0.0039 17.1 0.0 30 4.5 0.0 4.4 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_25 PF13481.6 RJW70532.1 - 0.007 16.0 0.1 0.6 9.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 RJW70532.1 - 0.015 15.8 8.1 5 7.6 0.0 5.6 5 0 0 5 5 3 0 ABC transporter NACHT PF05729.12 RJW70532.1 - 0.027 14.4 0.3 36 4.2 0.0 4.6 4 0 0 4 4 4 0 NACHT domain AAA_19 PF13245.6 RJW70532.1 - 0.061 13.7 8.9 0.18 12.1 0.0 5.5 6 0 0 6 6 4 0 AAA domain IstB_IS21 PF01695.17 RJW70532.1 - 2.7 7.7 11.0 2.1 8.0 0.0 5.0 6 0 0 6 6 5 0 IstB-like ATP binding protein EMP24_GP25L PF01105.24 RJW70532.1 - 5.3 6.9 9.7 2.8 7.8 1.6 3.4 3 0 0 3 3 2 0 emp24/gp25L/p24 family/GOLD GIY-YIG PF01541.24 RJW70535.1 - 9.7e-05 22.6 0.5 0.00064 20.0 0.4 2.2 2 0 0 2 2 2 1 GIY-YIG catalytic domain Integrin_alpha2 PF08441.12 RJW70536.1 - 0.031 13.2 0.0 0.14 11.0 0.0 1.9 2 0 0 2 2 2 0 Integrin alpha Integrin_alpha PF00357.20 RJW70536.1 - 0.13 12.3 1.0 0.31 11.1 1.0 1.7 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Adeno_E3_CR2 PF02439.15 RJW70536.1 - 0.14 11.9 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Collectrin PF16959.5 RJW70536.1 - 0.25 11.1 0.5 0.51 10.1 0.5 1.5 1 0 0 1 1 1 0 Renal amino acid transporter ABC_membrane PF00664.23 RJW70539.1 - 5.5e-55 186.9 12.1 6.3e-55 186.8 12.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF2878 PF11086.8 RJW70539.1 - 0.034 14.3 3.7 0.065 13.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2878) ATPase_gene1 PF09527.10 RJW70539.1 - 0.036 14.2 1.9 0.036 14.2 1.9 3.6 4 0 0 4 4 4 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Vps55 PF04133.14 RJW70539.1 - 0.18 11.8 6.9 0.16 11.9 0.3 2.7 2 1 0 2 2 2 0 Vacuolar protein sorting 55 DUF1398 PF07166.11 RJW70544.1 - 0.056 13.5 0.2 0.32 11.1 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1398) Glyco_transf_8 PF01501.20 RJW70545.1 - 5.4e-16 58.9 0.0 2.7e-14 53.4 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 RJW70545.1 - 0.0022 17.4 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 RJW70545.1 - 0.025 14.5 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Ion_trans PF00520.31 RJW70546.1 - 1.9e-14 53.5 5.6 2.6e-14 53.1 5.6 1.1 1 0 0 1 1 1 1 Ion transport protein DUF2770 PF10968.8 RJW70546.1 - 1.5 8.9 5.1 4.1 7.4 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) Foamy_virus_ENV PF03408.14 RJW70548.1 - 0.036 11.9 0.2 0.039 11.8 0.2 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein Myosin_head PF00063.21 RJW70549.1 - 1.7e-95 320.7 0.0 7.7e-87 292.1 0.0 2.9 2 1 0 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.6 RJW70549.1 - 0.0025 18.2 0.1 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RJW70549.1 - 0.0051 17.1 0.2 0.29 11.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 RJW70549.1 - 0.014 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 RJW70549.1 - 0.018 15.1 0.0 0.083 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RJW70549.1 - 0.076 13.6 0.0 1.7 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RJW70549.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain HRDC PF00570.23 RJW70550.1 - 0.033 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 HRDC domain ABC_tran PF00005.27 RJW70551.1 - 1.8e-71 239.0 0.1 3.4e-37 128.0 0.3 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RJW70551.1 - 1.5e-44 152.7 13.9 2.2e-44 152.2 13.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RJW70551.1 - 8e-14 51.6 3.1 1.6e-05 24.4 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RJW70551.1 - 3.3e-11 43.9 2.0 1.1e-05 25.9 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RJW70551.1 - 6.9e-11 42.3 0.0 0.0002 21.3 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 RJW70551.1 - 7.4e-10 38.2 0.1 0.0014 17.5 0.1 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 RJW70551.1 - 3.1e-09 37.1 0.0 0.12 12.1 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RJW70551.1 - 8.4e-09 35.8 2.4 0.0031 17.8 0.3 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RJW70551.1 - 1.2e-08 34.6 0.1 0.0032 17.2 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 RJW70551.1 - 5.6e-08 32.9 0.0 0.0099 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 RJW70551.1 - 3.6e-07 29.7 0.0 0.0096 15.1 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 RJW70551.1 - 8.6e-06 25.4 0.0 0.074 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 RJW70551.1 - 9.9e-06 25.6 0.4 0.035 14.0 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_23 PF13476.6 RJW70551.1 - 2.2e-05 25.1 0.2 0.11 13.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 RJW70551.1 - 2.8e-05 23.9 2.1 0.37 10.5 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RJW70551.1 - 4.1e-05 24.1 0.0 0.032 14.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RJW70551.1 - 4.9e-05 22.7 0.0 0.03 13.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 RJW70551.1 - 6.5e-05 23.0 0.0 0.45 10.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_5 PF07728.14 RJW70551.1 - 0.00013 21.9 0.1 0.35 10.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 RJW70551.1 - 0.00015 21.0 0.3 0.39 9.9 0.0 2.7 2 1 0 2 2 2 2 NB-ARC domain AAA PF00004.29 RJW70551.1 - 0.00022 21.7 0.4 21 5.6 0.0 4.5 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 RJW70551.1 - 0.00023 20.8 0.0 1.8 8.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 RJW70551.1 - 0.00034 20.9 0.1 0.66 10.2 0.3 3.6 3 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 RJW70551.1 - 0.00059 19.1 0.0 0.3 10.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) APS_kinase PF01583.20 RJW70551.1 - 0.00063 19.7 0.2 0.12 12.2 0.0 3.3 3 0 0 3 3 3 1 Adenylylsulphate kinase AAA_24 PF13479.6 RJW70551.1 - 0.00089 19.0 0.0 0.62 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RJW70551.1 - 0.0012 19.2 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.6 RJW70551.1 - 0.0012 19.0 5.4 0.62 10.3 1.1 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PRK PF00485.18 RJW70551.1 - 0.002 17.9 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 RJW70551.1 - 0.0021 17.9 0.0 0.22 11.3 0.0 2.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 RJW70551.1 - 0.0021 18.2 0.5 1.9 8.6 0.5 3.3 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 RJW70551.1 - 0.0025 17.5 0.5 0.22 11.1 0.0 2.6 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 RJW70551.1 - 0.0028 17.8 0.0 0.68 10.0 0.0 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain Roc PF08477.13 RJW70551.1 - 0.0034 17.6 0.1 5.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 RJW70551.1 - 0.0035 17.1 0.0 15 5.2 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 RJW70551.1 - 0.0047 16.6 0.0 7.2 6.3 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain TsaE PF02367.17 RJW70551.1 - 0.0064 16.5 0.0 4.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 RJW70551.1 - 0.0078 15.5 0.0 2.1 7.6 0.0 2.4 2 0 0 2 2 2 1 Septin FeoB_N PF02421.18 RJW70551.1 - 0.011 15.3 0.0 5.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.6 RJW70551.1 - 0.015 15.4 0.0 11 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 RJW70551.1 - 0.017 15.0 0.0 4.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain KAP_NTPase PF07693.14 RJW70551.1 - 0.021 14.1 0.0 3.7 6.7 0.0 2.7 2 1 0 2 2 2 0 KAP family P-loop domain DLIC PF05783.11 RJW70551.1 - 0.022 13.6 0.0 0.38 9.5 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_17 PF13207.6 RJW70551.1 - 0.022 15.2 0.3 3.7 8.0 0.0 3.2 3 1 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 RJW70551.1 - 0.022 14.5 0.5 2.6 7.8 0.1 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 RJW70551.1 - 0.023 14.7 0.0 2.2 8.3 0.0 2.7 2 0 0 2 2 2 0 Dynamin family MeaB PF03308.16 RJW70551.1 - 0.023 13.7 0.0 0.93 8.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB 6PF2K PF01591.18 RJW70551.1 - 0.026 13.8 0.0 0.099 11.9 0.0 1.9 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Ploopntkinase3 PF18751.1 RJW70551.1 - 0.03 14.2 0.0 4 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RuvX PF03652.15 RJW70551.1 - 0.032 14.6 0.1 0.21 12.0 0.0 2.3 2 0 0 2 2 2 0 Holliday junction resolvase NTPase_1 PF03266.15 RJW70551.1 - 0.033 14.1 0.0 12 5.8 0.0 2.8 2 0 0 2 2 2 0 NTPase MobB PF03205.14 RJW70551.1 - 0.072 13.0 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 RJW70551.1 - 0.095 12.0 0.1 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2291 PF10054.9 RJW70551.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 1 0 Predicted periplasmic lipoprotein (DUF2291) YidC_periplas PF14849.6 RJW70551.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 YidC periplasmic domain Ion_trans PF00520.31 RJW70552.1 - 1.7e-13 50.4 7.5 2e-13 50.1 7.5 1.1 1 0 0 1 1 1 1 Ion transport protein MMR_HSR1 PF01926.23 RJW70554.1 - 5e-15 55.6 0.0 1.1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_M PF16360.5 RJW70554.1 - 2e-06 28.3 7.5 4.9e-06 27.0 7.5 1.7 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 RJW70554.1 - 0.00054 20.6 0.0 0.0032 18.1 0.0 2.2 1 1 0 1 1 1 1 GTP-binding GTPase N-terminal ABC_tran PF00005.27 RJW70554.1 - 0.067 13.7 0.0 0.19 12.2 0.0 1.8 1 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 RJW70554.1 - 0.19 12.1 2.9 0.22 11.9 0.2 2.3 1 1 1 2 2 2 0 AAA ATPase domain cobW PF02492.19 RJW70554.1 - 0.2 11.2 0.1 12 5.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IBN_N PF03810.19 RJW70556.1 - 1.4e-14 53.7 1.3 1.9e-10 40.5 0.0 4.0 3 0 0 3 3 3 2 Importin-beta N-terminal domain RTP1_C1 PF10363.9 RJW70556.1 - 0.0044 17.2 0.7 0.087 13.0 0.1 3.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 RJW70556.1 - 0.0057 16.8 0.9 2.5 8.6 0.1 5.0 5 0 0 5 5 5 1 HEAT repeat Cse1 PF08506.10 RJW70556.1 - 0.011 14.6 0.0 0.055 12.3 0.0 2.3 1 0 0 1 1 1 0 Cse1 CLASP_N PF12348.8 RJW70556.1 - 0.025 14.2 0.2 1.2 8.6 0.4 2.7 2 0 0 2 2 2 0 CLASP N terminal Cnd1 PF12717.7 RJW70556.1 - 0.031 14.3 2.5 0.43 10.6 0.2 3.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 RJW70556.1 - 0.065 13.6 0.1 3.4 8.0 0.0 3.7 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain NUC130_3NT PF08158.12 RJW70556.1 - 0.18 12.1 1.8 7.5 7.0 0.9 3.0 2 0 0 2 2 2 0 NUC130/3NT domain BUD22 PF09073.10 RJW70556.1 - 0.29 10.4 8.5 0.7 9.2 8.5 1.6 1 0 0 1 1 1 0 BUD22 HEAT_EZ PF13513.6 RJW70556.1 - 0.65 10.6 8.8 0.48 11.0 0.3 4.3 2 1 1 3 3 3 0 HEAT-like repeat Nop14 PF04147.12 RJW70556.1 - 1.8 6.7 12.4 1.5 6.9 10.3 1.8 2 0 0 2 2 2 0 Nop14-like family FYDLN_acid PF09538.10 RJW70556.1 - 1.8 9.3 14.6 4.3 8.1 14.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Cwf_Cwc_15 PF04889.12 RJW70556.1 - 2.3 7.9 14.0 4.5 6.9 14.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Xpo1 PF08389.12 RJW70556.1 - 3 7.9 7.7 25 4.9 0.0 5.0 5 1 1 6 6 6 0 Exportin 1-like protein TRAP_alpha PF03896.16 RJW70556.1 - 4.7 6.3 6.5 9 5.4 6.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 RJW70556.1 - 8.5 5.7 12.3 13 5.1 12.3 1.2 1 0 0 1 1 1 0 SDA1 BAR PF03114.18 RJW70558.1 - 1.1e-43 149.7 4.8 1.4e-43 149.3 4.8 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 RJW70558.1 - 6.8e-10 38.6 4.6 9.6e-10 38.1 4.6 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 RJW70558.1 - 0.00085 19.1 4.7 0.0029 17.3 4.6 1.7 1 1 0 1 1 1 1 BAR domain of APPL family FAD_oxidored PF12831.7 RJW70558.1 - 0.02 14.3 0.1 0.026 13.9 0.1 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase MHC_II_beta PF00969.19 RJW70558.1 - 0.035 14.2 0.1 0.078 13.1 0.0 1.6 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain zf-RING_UBOX PF13445.6 RJW70561.1 - 1e-07 31.8 8.9 1e-07 31.8 8.9 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RJW70561.1 - 2e-07 30.7 5.5 2e-07 30.7 5.5 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW70561.1 - 4e-06 26.6 12.2 4e-06 26.6 12.2 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RJW70561.1 - 4.9e-05 23.1 6.1 4.9e-05 23.1 6.1 3.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RJW70561.1 - 0.0026 17.7 13.3 0.0026 17.7 13.3 4.0 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RJW70561.1 - 0.0038 17.4 12.8 0.0038 17.4 12.8 3.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING OrfB_Zn_ribbon PF07282.11 RJW70561.1 - 0.0047 16.8 4.0 0.39 10.7 0.1 3.0 2 0 0 2 2 2 2 Putative transposase DNA-binding domain U-box PF04564.15 RJW70561.1 - 0.018 15.2 0.0 0.076 13.2 0.0 2.0 2 0 0 2 2 2 0 U-box domain zf-C3HC4_3 PF13920.6 RJW70561.1 - 0.027 14.3 15.3 0.027 14.3 15.3 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW70561.1 - 0.032 14.6 18.2 0.032 14.6 18.2 3.6 3 1 0 3 3 2 0 Ring finger domain S36_mt PF10937.8 RJW70561.1 - 0.24 13.0 1.6 0.54 11.9 1.6 1.5 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial zf-RING_6 PF14835.6 RJW70561.1 - 4.1 7.3 16.8 0.71 9.8 5.4 2.8 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf_UBZ PF18439.1 RJW70561.1 - 4.1 7.1 9.9 1.9 8.2 0.2 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Cation_efflux PF01545.21 RJW70563.1 - 1.3e-28 100.2 0.5 1.6e-28 99.8 0.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 RJW70563.1 - 9.4e-10 38.5 0.7 3e-09 36.9 0.7 1.8 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter TMEM192 PF14802.6 RJW70563.1 - 0.0058 15.8 0.0 0.0099 15.0 0.0 1.3 1 0 0 1 1 1 1 TMEM192 family DUF1405 PF07187.11 RJW70563.1 - 0.073 13.1 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1405) DUF5408 PF17402.2 RJW70563.1 - 0.09 12.7 0.8 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5408) DpnI_C PF17726.1 RJW70564.1 - 0.37 11.0 4.6 7.1 6.8 0.2 3.6 3 0 0 3 3 3 0 Dam-replacing HTH domain Sec63 PF02889.16 RJW70566.1 - 5.9e-158 523.7 0.1 2e-85 286.0 0.0 2.6 2 0 0 2 2 2 2 Sec63 Brl domain RVT_1 PF00078.27 RJW70566.1 - 1e-45 156.0 0.0 2.7e-45 154.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD PF00270.29 RJW70566.1 - 6.4e-43 146.5 0.0 2.2e-22 79.7 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 RJW70566.1 - 9.8e-35 119.1 0.1 3.6e-34 117.3 0.1 2.1 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 RJW70566.1 - 2.2e-19 70.1 0.0 4.7e-10 39.7 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Exo_endo_phos_2 PF14529.6 RJW70566.1 - 1.6e-11 44.1 0.1 1.8e-10 40.7 0.0 3.1 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Helicase_C PF00271.31 RJW70566.1 - 2.9e-07 30.8 0.0 3.6e-06 27.3 0.0 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RJW70566.1 - 0.0004 20.7 0.2 0.28 11.4 0.0 3.9 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 RJW70566.1 - 0.003 16.7 0.0 0.14 11.2 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 RJW70566.1 - 0.14 11.6 0.0 17 4.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Dickkopf_N PF04706.12 RJW70567.1 - 0.25 11.9 16.1 0.33 11.5 3.1 2.6 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Conotoxin_I2 PF17557.2 RJW70567.1 - 4.5 7.5 23.0 2 8.6 6.2 2.4 2 0 0 2 2 2 0 I2-superfamily conotoxins Inositol_P PF00459.25 RJW70571.1 - 3.8e-36 125.0 0.0 5.6e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Tetraspanin PF00335.20 RJW70572.1 - 4.7e-14 52.7 0.0 7.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Tetraspanin family Ribosomal_S27e PF01667.17 RJW70573.1 - 0.071 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 DDE_3 PF13358.6 RJW70573.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Med14 PF08638.11 RJW70573.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit MED14 YchF-GTPase_C PF06071.13 RJW70576.1 - 3.7e-40 136.0 1.1 8e-40 134.9 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 RJW70576.1 - 6.6e-23 81.0 0.0 1.7e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RJW70576.1 - 9.9e-07 28.4 0.0 2.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 RJW70576.1 - 0.0038 17.2 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MeaB PF03308.16 RJW70576.1 - 0.087 11.8 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 RJW70576.1 - 0.19 11.7 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Dynamin family WD40 PF00400.32 RJW70577.1 - 5.1e-07 30.3 13.7 0.062 14.2 0.1 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Dynein_IC2 PF11540.8 RJW70577.1 - 0.00011 22.1 0.7 0.00022 21.1 0.7 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 PF12894.7 RJW70577.1 - 0.13 12.6 0.1 0.52 10.7 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RRF PF01765.19 RJW70578.1 - 0.0002 21.4 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 2 Ribosome recycling factor YlqD PF11068.8 RJW70578.1 - 0.038 14.4 0.8 0.085 13.2 0.0 1.9 2 0 0 2 2 2 0 YlqD protein WD40 PF00400.32 RJW70579.1 - 2e-14 53.7 0.5 0.0037 18.1 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW70579.1 - 2.6e-05 24.4 0.0 1.3 9.3 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW70579.1 - 0.11 11.4 0.0 4.9 6.0 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RVT_1 PF00078.27 RJW70580.1 - 1.9e-45 155.1 0.0 2.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANTH PF07651.16 RJW70581.1 - 3.1e-33 115.0 0.1 4.1e-33 114.5 0.1 1.2 1 0 0 1 1 1 1 ANTH domain Actin PF00022.19 RJW70582.1 - 9.6e-136 452.6 0.0 3.3e-135 450.8 0.0 1.7 1 1 0 1 1 1 1 Actin LSDAT_euk PF18139.1 RJW70583.1 - 4.6e-25 88.5 0.0 6.5e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM CAF1C_H4-bd PF12265.8 RJW70583.1 - 0.0016 18.7 0.1 4.6 7.6 0.0 2.9 2 0 0 2 2 2 2 Histone-binding protein RBBP4 or subunit C of CAF1 complex LSDAT_prok PF18171.1 RJW70583.1 - 0.0062 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote HLH PF00010.26 RJW70587.1 - 1.2e-11 44.3 4.6 2.9e-11 43.2 4.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Basic PF01586.16 RJW70587.1 - 2.7e-11 44.5 0.2 2.3e-10 41.5 0.2 2.7 1 0 0 1 1 1 1 Myogenic Basic domain DUF719 PF05334.13 RJW70587.1 - 2.3 8.4 5.0 0.7 10.1 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DSPc PF00782.20 RJW70588.1 - 2.6e-12 46.7 0.0 4.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RNase_P_Rpp14 PF01900.19 RJW70589.1 - 2.6e-19 69.4 0.0 5.4e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Rpp14/Pop5 family zf-C3HC4_3 PF13920.6 RJW70589.1 - 7.5e-12 44.9 5.8 2.1e-11 43.5 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW70589.1 - 2.6e-11 43.2 9.0 6.9e-11 41.8 9.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW70589.1 - 1.4e-10 41.3 9.9 1.4e-10 41.3 9.9 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 RJW70589.1 - 3.7e-09 36.3 7.5 9.3e-09 35.0 7.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RJW70589.1 - 1e-08 34.9 7.1 2.4e-08 33.7 7.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RJW70589.1 - 8.9e-08 32.0 4.8 9.4e-08 32.0 2.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RJW70589.1 - 4.4e-06 26.5 6.4 4.4e-06 26.5 6.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 RJW70589.1 - 6.1e-06 26.4 6.9 1.7e-05 25.0 6.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RJW70589.1 - 0.0032 17.6 9.0 0.0085 16.2 9.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RJW70589.1 - 0.0093 16.0 2.0 0.0093 16.0 2.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 RJW70589.1 - 0.029 13.7 0.3 0.057 12.8 0.2 1.3 1 1 0 1 1 1 0 Rtf2 RING-finger zf-P11 PF03854.14 RJW70589.1 - 0.04 13.6 6.8 0.11 12.2 6.8 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-UDP PF14569.6 RJW70589.1 - 0.047 13.8 1.9 0.12 12.5 1.9 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 RJW70589.1 - 0.089 12.6 6.4 0.3 10.9 6.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RecR PF02132.15 RJW70589.1 - 0.15 11.6 0.8 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 RecR protein Baculo_IE-1 PF05290.11 RJW70589.1 - 0.3 11.0 4.3 0.58 10.1 4.3 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) IBR PF01485.21 RJW70589.1 - 0.84 9.9 7.5 1.1 9.5 5.3 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Coprogen_oxidas PF01218.18 RJW70594.1 - 5.8e-32 110.6 0.0 6.5e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase ETF_alpha PF00766.19 RJW70595.1 - 2.5e-38 130.0 1.4 5.2e-38 129.0 0.3 2.0 2 1 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 RJW70595.1 - 1.9e-36 125.6 0.1 3.4e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain zf-C4 PF00105.18 RJW70596.1 - 1.5e-30 105.5 13.6 2.8e-30 104.6 13.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW70596.1 - 1.6e-10 40.9 0.1 2.6e-05 23.9 0.1 2.3 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor XRCC1_N PF01834.16 RJW70597.1 - 1.6e-44 151.5 0.1 2.8e-44 150.7 0.1 1.4 1 0 0 1 1 1 1 XRCC1 N terminal domain BRCT_2 PF16589.5 RJW70597.1 - 2.1e-18 66.5 0.0 3.8e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 RJW70597.1 - 1.5e-17 63.7 0.0 3.3e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 RJW70597.1 - 6.7e-10 38.8 0.0 1.1e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 RJW70597.1 - 1e-06 28.9 0.0 7.5e-05 22.9 0.0 2.9 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 RJW70597.1 - 0.097 12.6 0.0 0.71 9.8 0.0 2.2 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Nop14 PF04147.12 RJW70597.1 - 2.2 6.4 16.5 3.2 5.8 16.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RJW70597.1 - 9.4 4.4 16.6 14 3.8 16.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DAGAT PF03982.13 RJW70598.1 - 0.027 13.4 0.0 0.071 12.0 0.0 1.8 1 1 0 1 1 1 0 Diacylglycerol acyltransferase Acyltransferase PF01553.21 RJW70598.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase fn3 PF00041.21 RJW70599.1 - 3.5e-10 40.1 0.1 3.5e-06 27.3 0.0 4.1 4 0 0 4 4 4 2 Fibronectin type III domain Interfer-bind PF09294.10 RJW70599.1 - 0.0038 17.5 0.0 3 8.2 0.0 2.8 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 RJW70599.1 - 0.026 15.1 0.4 0.22 12.1 0.4 2.7 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain WD40 PF00400.32 RJW70600.1 - 1.5e-06 28.8 4.1 4.6 8.3 0.0 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW70600.1 - 0.0014 18.9 0.0 0.36 11.2 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1279 PF06916.13 RJW70601.1 - 1.3e-11 44.9 0.1 1.9e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) RRM_1 PF00076.22 RJW70604.1 - 1.5e-05 24.8 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NatB_MDM20 PF09797.9 RJW70607.1 - 3.7e-26 92.0 0.0 7e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DASH_Duo1 PF08651.10 RJW70607.1 - 0.021 14.6 0.6 0.11 12.3 0.5 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 E2_bind PF08825.10 RJW70607.1 - 0.096 12.8 0.1 0.46 10.7 0.0 2.2 2 0 0 2 2 2 0 E2 binding domain Actin PF00022.19 RJW70608.1 - 1e-147 492.0 0.0 3.3e-147 490.3 0.0 1.6 1 1 0 1 1 1 1 Actin zf-C2H2 PF00096.26 RJW70609.1 - 0.0013 19.0 9.2 0.014 15.8 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW70609.1 - 0.036 14.5 14.2 0.29 11.6 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain FOXP-CC PF16159.5 RJW70609.1 - 0.092 13.4 0.5 12 6.6 0.1 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 RJW70609.1 - 0.11 13.3 0.3 0.11 13.3 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Actin PF00022.19 RJW70610.1 - 8.2e-152 505.5 0.0 2.7e-151 503.8 0.0 1.6 1 1 0 1 1 1 1 Actin ATP-synt_C PF00137.21 RJW70612.1 - 3.7e-36 123.3 39.8 3.8e-21 75.2 15.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 RJW70612.1 - 0.78 9.5 4.4 4.5 7.0 0.3 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain GerA PF03323.13 RJW70612.1 - 1.6 7.1 5.8 7.1 5.0 0.1 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein T-box PF00907.22 RJW70613.1 - 9.1e-56 189.0 0.1 6.2e-55 186.3 0.0 2.1 2 0 0 2 2 2 1 T-box Glyco_hydro_36C PF16874.5 RJW70613.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 C-terminal domain Galactosyl_T PF01762.21 RJW70616.1 - 5.7e-08 32.8 0.0 9.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase DUF2457 PF10446.9 RJW70616.1 - 7.6 5.6 7.1 10 5.2 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SPATA6 PF14909.6 RJW70618.1 - 2.1e-21 76.5 0.0 4.4e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 PPP4R2 PF09184.11 RJW70620.1 - 0.00038 20.2 15.7 0.00046 19.9 15.7 1.2 1 0 0 1 1 1 1 PPP4R2 Nop14 PF04147.12 RJW70620.1 - 0.0035 15.7 20.0 0.0037 15.6 20.0 1.1 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.13 RJW70620.1 - 0.03 14.3 19.9 0.036 14.1 19.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.13 RJW70620.1 - 0.056 13.3 16.3 0.082 12.8 16.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Paf1 PF03985.13 RJW70620.1 - 0.064 12.2 10.7 0.081 11.9 10.7 1.2 1 0 0 1 1 1 0 Paf1 RPN2_C PF18004.1 RJW70620.1 - 0.2 11.6 4.2 0.27 11.1 4.2 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Serinc PF03348.15 RJW70620.1 - 0.31 9.9 0.3 0.38 9.6 0.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CobT PF06213.12 RJW70620.1 - 0.43 9.9 21.9 0.6 9.5 20.6 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 RJW70620.1 - 0.78 8.7 3.3 0.87 8.5 3.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Drc1-Sld2 PF11719.8 RJW70620.1 - 0.92 9.0 10.0 1.2 8.6 10.0 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein DNA_pol_phi PF04931.13 RJW70620.1 - 2.4 6.2 40.3 3.4 5.6 40.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi FYDLN_acid PF09538.10 RJW70620.1 - 3.7 8.3 25.1 8.8 7.1 25.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RNA_pol_Rpc4 PF05132.14 RJW70620.1 - 4.5 7.7 6.4 12 6.3 6.4 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2428 PF10350.9 RJW70620.1 - 6.8 5.9 6.6 11 5.2 6.6 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) DUF2076 PF09849.9 RJW70620.1 - 9.2 6.2 12.0 12 5.8 12.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) 5_nucleotid_C PF02872.18 RJW70625.1 - 3.2e-35 121.7 0.0 5.9e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RJW70625.1 - 1.7e-08 35.2 0.1 3.2e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L18p PF00861.22 RJW70625.1 - 0.0062 16.9 0.8 0.013 15.9 0.8 1.4 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Endonuclease_NS PF01223.23 RJW70626.1 - 3.3e-55 187.4 0.0 4.1e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Coprogen_oxidas PF01218.18 RJW70627.1 - 1.2e-76 257.3 0.1 1.4e-76 257.1 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PCNA_N PF00705.18 RJW70628.1 - 2e-54 182.7 1.6 1.7e-53 179.7 1.9 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 RJW70628.1 - 2.3e-43 147.4 0.1 6.6e-43 145.9 0.1 1.8 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 RJW70628.1 - 5.9e-07 28.8 0.8 0.00019 20.6 0.8 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 RJW70628.1 - 4.6e-05 23.0 0.1 8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 RJW70628.1 - 0.0017 17.5 0.0 0.0077 15.4 0.0 1.9 2 0 0 2 2 2 1 Hus1-like protein DUF2656 PF10847.8 RJW70628.1 - 0.012 15.7 0.0 0.38 10.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) Exo_endo_phos PF03372.23 RJW70628.1 - 0.024 14.1 0.1 0.054 13.0 0.1 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 RJW70633.1 - 2.7e-63 213.8 0.0 3.5e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW70633.1 - 2.9e-31 108.7 0.0 4.2e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW70633.1 - 1.4e-06 27.5 0.0 2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RVT_1 PF00078.27 RJW70633.1 - 3.1e-05 23.6 0.0 5.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.23 RJW70633.1 - 0.00036 20.5 0.2 0.0023 17.9 0.1 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RJW70633.1 - 0.0062 15.9 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RJW70633.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 RJW70633.1 - 0.2 11.2 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Mur_ligase_M PF08245.12 RJW70634.1 - 3.7e-08 33.6 0.0 7.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain DUF4223 PF13978.6 RJW70634.1 - 0.037 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Mur_ligase_C PF02875.21 RJW70634.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF3591 PF12157.8 RJW70636.1 - 7.7e-144 479.6 0.0 2.7e-143 477.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 RJW70636.1 - 3.3e-39 132.8 2.4 3.6e-19 68.6 0.1 2.5 2 0 0 2 2 2 2 Bromodomain zf-CCHC_6 PF15288.6 RJW70636.1 - 5.6e-08 32.5 1.1 1.5e-07 31.1 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle TBP-binding PF09247.11 RJW70636.1 - 2.2e-05 24.6 0.6 6.3e-05 23.1 0.6 1.7 1 0 0 1 1 1 1 TATA box-binding protein binding Galactosyl_T PF01762.21 RJW70639.1 - 3.2e-26 92.3 0.0 1e-22 80.9 0.0 2.1 2 0 0 2 2 2 2 Galactosyltransferase fn3 PF00041.21 RJW70640.1 - 6.1e-16 58.5 0.3 1.2e-05 25.5 0.0 3.5 3 1 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW70640.1 - 1.4e-05 25.6 0.2 0.37 11.4 0.0 3.5 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RJW70640.1 - 4.4e-05 23.8 0.4 0.92 9.9 0.0 3.1 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III LIFR_D2 PF17971.1 RJW70640.1 - 0.012 15.7 1.0 2 8.6 0.1 2.5 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain DUF2369 PF10179.9 RJW70640.1 - 0.039 14.3 0.1 0.2 12.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) Acyl-CoA_dh_1 PF00441.24 RJW70641.1 - 2.6e-51 173.8 2.7 5.3e-51 172.8 2.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RJW70641.1 - 1.9e-26 92.9 0.1 4.7e-26 91.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RJW70641.1 - 1e-25 89.8 0.2 1.6e-25 89.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RJW70641.1 - 1.4e-23 83.6 1.5 2.2e-23 83.0 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Coronavirus_5 PF05528.11 RJW70641.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Coronavirus gene 5 protein VPS9 PF02204.18 RJW70642.1 - 7.3e-16 58.3 0.0 1.7e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Secretin_N PF03958.17 RJW70642.1 - 0.069 13.6 0.5 0.55 10.7 0.3 2.7 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain SIX1_SD PF16878.5 RJW70643.1 - 4.3e-24 85.2 2.1 3.9e-23 82.1 0.6 2.1 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 RJW70643.1 - 4.1e-05 23.3 1.0 0.0001 22.1 0.1 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RJW70643.1 - 0.0019 18.0 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Cullin PF00888.22 RJW70645.1 - 1.3e-167 559.2 9.0 1.8e-166 555.4 9.0 2.0 1 1 0 1 1 1 1 Cullin family zf-MYND PF01753.18 RJW70646.1 - 0.019 15.0 6.3 0.019 15.0 6.3 2.1 2 0 0 2 2 2 0 MYND finger DUF2321 PF10083.9 RJW70646.1 - 0.022 14.4 0.2 0.065 12.9 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF3090 PF11290.8 RJW70646.1 - 0.046 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) zf-C4_ClpX PF06689.13 RJW70646.1 - 3.6 7.5 7.3 8.1 6.4 0.2 3.4 4 0 0 4 4 4 0 ClpX C4-type zinc finger zf-HIT PF04438.16 RJW70646.1 - 5.6 6.9 11.9 3.6 7.5 5.0 2.5 2 0 0 2 2 2 0 HIT zinc finger RRM_1 PF00076.22 RJW70647.1 - 1.7e-34 117.4 0.2 2.4e-16 59.3 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW70647.1 - 3.6e-12 46.2 0.2 5.5e-07 29.6 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif RL PF17797.1 RJW70647.1 - 0.0011 18.9 0.0 2.3 8.2 0.0 2.6 2 0 0 2 2 2 2 RL domain Laminin_G_1 PF00054.23 RJW70647.1 - 0.058 13.6 0.0 7.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Laminin G domain Cas_Cas2CT1978 PF09707.10 RJW70647.1 - 0.065 13.3 0.0 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.11 RJW70647.1 - 0.073 12.8 0.2 4.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain LA-virus_coat PF09220.10 RJW70647.1 - 0.1 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 L-A virus, major coat protein Cation_ATPase_C PF00689.21 RJW70649.1 - 3.4e-43 147.5 8.0 3.4e-43 147.5 8.0 1.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 RJW70649.1 - 5.6e-18 64.8 0.0 1.3e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RJW70649.1 - 1.9e-12 47.9 0.0 7.9e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.8 RJW70649.1 - 1.7e-11 44.4 0.3 6e-11 42.7 0.3 2.0 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 RJW70649.1 - 1.5e-07 31.5 0.6 1.6e-05 24.8 0.1 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Ribosomal_60s PF00428.19 RJW70649.1 - 5.2 7.7 8.8 11 6.7 8.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Actin PF00022.19 RJW70651.1 - 5.5e-120 400.7 0.0 6.1e-120 400.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RJW70651.1 - 0.003 16.4 0.0 0.96 8.2 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein HOOK PF05622.12 RJW70652.1 - 1.1e-10 40.4 0.0 1.1e-10 40.4 0.0 6.4 3 1 2 5 5 5 2 HOOK protein ZapB PF06005.12 RJW70652.1 - 0.0025 18.2 1.2 0.0025 18.2 1.2 16.3 8 4 3 11 11 11 1 Cell division protein ZapB DUF1664 PF07889.12 RJW70652.1 - 0.011 15.8 1.7 0.011 15.8 1.7 11.1 8 5 6 14 14 14 0 Protein of unknown function (DUF1664) E1-E2_ATPase PF00122.20 RJW70653.1 - 2.6e-38 131.4 12.2 2.7e-26 92.2 0.3 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 RJW70653.1 - 5e-15 54.9 0.0 1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2976 PF11190.8 RJW70653.1 - 0.0067 16.2 8.3 0.21 11.4 1.7 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2976) DUF4231 PF14015.6 RJW70653.1 - 0.011 16.2 2.4 0.15 12.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) ATG22 PF11700.8 RJW70653.1 - 0.012 14.3 0.4 0.055 12.1 0.0 2.0 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like TctB PF07331.11 RJW70653.1 - 0.033 14.5 1.9 5.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF898 PF05987.13 RJW70653.1 - 0.064 12.3 2.8 0.92 8.5 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF3619 PF12279.8 RJW70653.1 - 0.076 13.4 2.6 8.2 6.8 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) Cytomega_TRL10 PF06084.11 RJW70653.1 - 0.14 12.2 0.1 3.7 7.6 0.0 2.6 3 0 0 3 3 3 0 Cytomegalovirus TRL10 protein Pox_EPC_I2-L1 PF12575.8 RJW70653.1 - 0.64 10.3 4.0 17 5.7 0.0 3.0 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 Yip1 PF04893.17 RJW70653.1 - 0.65 9.7 5.1 0.39 10.4 1.1 2.1 2 0 0 2 2 2 0 Yip1 domain DUF202 PF02656.15 RJW70653.1 - 0.9 10.0 5.1 4.3 7.8 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Pox_A14 PF05767.12 RJW70653.1 - 2.3 8.4 6.3 10 6.3 0.4 3.0 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 DUF1461 PF07314.11 RJW70653.1 - 2.4 8.0 5.8 2.1 8.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF2681 PF10883.8 RJW70653.1 - 7.7 7.0 6.9 46 4.5 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) UQ_con PF00179.26 RJW70656.1 - 3.8e-43 146.5 0.0 4.3e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RJW70656.1 - 0.0011 18.9 0.0 0.0018 18.1 0.0 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 RJW70656.1 - 0.0025 17.5 0.0 0.0031 17.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RJW70656.1 - 0.026 14.8 0.0 0.033 14.5 0.0 1.2 1 0 0 1 1 1 0 RWD domain ATP12 PF07542.11 RJW70657.1 - 1.9e-32 112.0 0.1 3.3e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein ATLF PF07737.11 RJW70658.1 - 0.23 10.7 0.1 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain Peptidase_S8 PF00082.22 RJW70659.1 - 2.4e-29 102.6 0.1 3.4e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 RJW70659.1 - 1.1e-14 54.2 0.1 2.5e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Ribosomal_S19e PF01090.19 RJW70660.1 - 0.093 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S19e PDZ PF00595.24 RJW70662.1 - 1.7e-14 53.9 0.0 2.5e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW70662.1 - 2.6e-05 24.0 0.0 5.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW70662.1 - 0.00024 21.4 0.0 0.00036 20.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Peptidase_C13 PF01650.18 RJW70663.1 - 1.4e-106 355.7 1.9 2.5e-106 354.9 1.9 1.3 1 0 0 1 1 1 1 Peptidase C13 family Pkinase PF00069.25 RJW70664.1 - 1.5e-64 217.9 0.0 1.8e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW70664.1 - 2.8e-33 115.3 0.0 4.3e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW70664.1 - 0.0021 18.0 0.1 0.0058 16.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RJW70664.1 - 0.0062 15.5 0.4 0.0092 15.0 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 RJW70664.1 - 0.007 15.2 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Pkinase_fungal PF17667.1 RJW70664.1 - 0.17 10.6 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase EPL1 PF10513.9 RJW70665.1 - 4.4e-11 43.4 0.8 7.7e-11 42.6 0.2 1.7 2 0 0 2 2 2 1 Enhancer of polycomb-like Carb_anhydrase PF00194.21 RJW70666.1 - 3.1e-70 236.6 0.1 4.4e-70 236.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF5488 PF17590.2 RJW70666.1 - 0.13 12.0 1.3 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5488) PseudoU_synth_2 PF00849.22 RJW70667.1 - 5.8e-28 98.0 0.0 1.5e-27 96.6 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase Pkinase_Tyr PF07714.17 RJW70671.1 - 1.3e-42 145.9 0.0 1.1e-32 113.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW70671.1 - 2.6e-40 138.5 0.0 6.1e-39 134.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RJW70671.1 - 0.0027 17.1 0.1 0.0047 16.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RJW70671.1 - 0.0036 16.9 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Carb_anhydrase PF00194.21 RJW70673.1 - 2.7e-72 243.4 0.3 3.2e-72 243.1 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase UCR_6-4kD PF08997.10 RJW70673.1 - 0.018 15.0 0.2 0.035 14.0 0.2 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein AHSA1 PF08327.11 RJW70674.1 - 1.1e-15 57.9 0.0 2.2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Aha1_N PF09229.11 RJW70674.1 - 2.4e-11 44.0 0.1 7.9e-10 39.1 0.0 2.4 2 1 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal RVT_1 PF00078.27 RJW70674.1 - 3.5e-08 33.3 0.0 6.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flexi_CP_N PF08358.10 RJW70675.1 - 0.15 12.1 0.6 11 6.0 0.4 2.9 2 0 0 2 2 2 0 Carlavirus coat BAR PF03114.18 RJW70675.1 - 0.3 10.7 6.2 7.8 6.1 4.2 2.5 2 0 0 2 2 2 0 BAR domain RAB3GAP2_N PF14655.6 RJW70678.1 - 1.5e-36 126.5 0.0 2.2e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_C PF14656.6 RJW70678.1 - 1.1e-33 116.3 0.3 1e-19 70.3 0.1 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit C-terminus CAP_C PF08603.11 RJW70679.1 - 1.2e-51 174.5 5.5 1.5e-51 174.1 5.5 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 RJW70679.1 - 5.1e-15 55.8 0.7 6.6e-15 55.4 0.0 1.5 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 RJW70679.1 - 1.1e-05 25.2 9.9 7.1e-05 22.5 4.5 1.7 1 1 1 2 2 2 2 Tubulin binding cofactor C Phosphoprotein PF00922.17 RJW70679.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DUF1966 PF09260.11 RJW70679.1 - 0.43 10.9 3.6 2.2 8.6 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1966) DEAD PF00270.29 RJW70680.1 - 2.8e-41 141.2 0.1 4.8e-41 140.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW70680.1 - 1.1e-32 112.6 0.1 3.5e-31 107.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 RJW70680.1 - 3.7e-06 27.3 0.1 2.5e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RJW70680.1 - 4.7e-06 26.7 0.0 1.5e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 RJW70680.1 - 1.3e-05 25.0 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 RJW70680.1 - 0.00077 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 RJW70680.1 - 0.0022 17.6 0.3 0.0029 17.2 0.3 1.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UTP25 PF06862.12 RJW70680.1 - 0.0031 16.4 0.1 1.3 7.7 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 RJW70680.1 - 0.019 15.2 0.4 0.11 12.7 0.4 2.1 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 RJW70680.1 - 0.037 13.4 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) AAA_11 PF13086.6 RJW70680.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain SWI2_SNF2 PF18766.1 RJW70680.1 - 0.74 9.4 4.5 2.5 7.7 0.1 2.9 3 0 0 3 3 3 0 SWI2/SNF2 ATPase FAM91_C PF14648.6 RJW70682.1 - 2.5e-142 474.7 0.0 3.2e-142 474.4 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 RJW70682.1 - 4.6e-109 364.5 0.2 7.2e-109 363.8 0.2 1.2 1 0 0 1 1 1 1 FAM91 N-terminus Methyltransf_28 PF02636.17 RJW70684.1 - 2e-42 145.6 0.0 2.5e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCNP PF15473.6 RJW70685.1 - 1.6e-07 32.2 0.0 2.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family Chitin_synth_1N PF08407.11 RJW70685.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Chitin synthase N-terminal Carb_anhydrase PF00194.21 RJW70686.1 - 3.2e-68 230.0 0.0 3.6e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF2228 PF10228.9 RJW70687.1 - 3.8e-66 223.4 0.0 3.3e-65 220.3 0.0 2.1 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2228) Cadherin_2 PF08266.12 RJW70689.1 - 0.0082 16.0 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Cadherin-like zf-met PF12874.7 RJW70690.1 - 3.3e-07 30.5 1.8 1e-06 28.9 1.8 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW70690.1 - 0.00023 21.4 2.1 0.0006 20.0 2.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 RJW70690.1 - 0.0014 18.4 0.3 0.0014 18.4 0.3 2.0 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2_6 PF13912.6 RJW70690.1 - 0.0022 18.0 1.1 0.0045 17.0 1.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger RVT_1 PF00078.27 RJW70690.1 - 0.021 14.4 0.1 0.064 12.8 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) HoxA13_N PF12284.8 RJW70690.1 - 0.058 14.0 0.1 0.29 11.8 0.1 2.3 1 0 0 1 1 1 0 Hox protein A13 N terminal Zn_ribbon_SprT PF17283.2 RJW70690.1 - 0.061 13.2 0.1 0.23 11.4 0.1 2.0 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DUF29 PF01724.16 RJW70690.1 - 0.067 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF29 DUF648 PF04890.13 RJW70690.1 - 0.069 12.9 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) zf-C2H2_4 PF13894.6 RJW70690.1 - 0.1 13.5 0.3 0.67 10.9 0.3 2.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RJW70690.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PCI PF01399.27 RJW70691.1 - 1.5e-05 25.4 0.1 3.5e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 PCI domain zf-H2C2_2 PF13465.6 RJW70692.1 - 1.5e-05 25.1 1.0 0.31 11.6 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain PreAtp-grasp PF18604.1 RJW70692.1 - 0.13 11.9 0.0 6.2 6.5 0.0 2.3 2 1 0 2 2 2 0 Pre ATP-grasp domain HTH_55 PF18622.1 RJW70692.1 - 0.14 12.5 0.0 17 5.8 0.0 2.2 2 0 0 2 2 2 0 RctB helix turn helix domain ZU5 PF00791.20 RJW70693.1 - 0.017 15.4 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 ZU5 domain DUF2451 PF10474.9 RJW70694.1 - 6.9e-88 294.4 0.1 2.1e-87 292.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 RJW70694.1 - 5.8e-48 163.6 1.0 1.3e-47 162.5 1.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex BDHCT_assoc PF16204.5 RJW70697.1 - 0.37 10.4 5.7 0.53 9.9 5.7 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Ferrochelatase PF00762.19 RJW70699.1 - 1.9e-96 322.9 0.0 2.7e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 Ferrochelatase HEAT_2 PF13646.6 RJW70700.1 - 5e-08 33.2 14.9 0.023 15.1 0.0 8.0 7 1 0 8 8 8 2 HEAT repeats HEAT PF02985.22 RJW70700.1 - 4.8e-05 23.3 31.0 1.3 9.5 0.9 9.9 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 RJW70700.1 - 0.00085 19.9 0.7 0.023 15.3 0.2 3.0 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 RJW70700.1 - 0.016 13.8 5.9 1.3 7.5 0.0 3.6 4 0 0 4 4 4 0 Adaptin N terminal region Cnd1 PF12717.7 RJW70700.1 - 0.027 14.5 3.7 3 7.9 0.1 3.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 RJW70700.1 - 3.3 7.6 7.0 35 4.3 0.0 4.7 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HPD PF05044.12 RJW70702.1 - 5.1e-67 224.6 1.3 7.5e-67 224.0 1.3 1.3 1 0 0 1 1 1 1 Homeo-prospero domain CG-1 PF03859.16 RJW70703.1 - 1.4e-33 115.1 0.2 2.9e-33 114.1 0.2 1.5 1 0 0 1 1 1 1 CG-1 domain Peptidase_C13 PF01650.18 RJW70704.1 - 9.5e-107 356.3 0.5 1.4e-106 355.7 0.1 1.4 2 0 0 2 2 2 1 Peptidase C13 family Peptidase_C14 PF00656.22 RJW70704.1 - 0.00034 20.6 0.0 0.00046 20.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain PID PF00640.23 RJW70706.1 - 1.5e-24 86.6 0.4 2.7e-24 85.8 0.4 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) NumbF PF06311.12 RJW70706.1 - 1.4e-19 70.4 0.6 4.9e-19 68.7 0.6 2.0 1 0 0 1 1 1 1 NUMB domain PID_2 PF14719.6 RJW70706.1 - 2.4e-06 27.5 0.1 3.7e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 RJW70706.1 - 0.0094 16.1 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine-binding domain Carb_anhydrase PF00194.21 RJW70707.1 - 8.7e-76 254.8 0.1 1.1e-75 254.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase 7tm_1 PF00001.21 RJW70708.1 - 1.3e-07 31.2 9.5 6.4e-06 25.7 0.6 2.8 3 0 0 3 3 3 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW70708.1 - 0.0031 16.9 2.8 0.094 12.0 0.3 2.7 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw EPL1 PF10513.9 RJW70709.1 - 1.4e-10 41.8 1.6 1.5e-10 41.6 0.2 1.8 2 0 0 2 2 2 1 Enhancer of polycomb-like GAS PF13851.6 RJW70710.1 - 0.00093 18.6 11.7 0.00093 18.6 11.7 4.8 3 1 2 5 5 5 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 RJW70710.1 - 0.006 16.8 15.8 0.006 16.8 15.8 5.2 2 2 2 5 5 5 3 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 RJW70710.1 - 0.048 13.0 33.5 0.094 12.1 1.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF1406 PF07190.11 RJW70710.1 - 0.16 11.9 1.5 0.32 10.9 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1406) Spc7 PF08317.11 RJW70710.1 - 0.46 9.3 52.7 0.092 11.6 20.6 3.9 3 1 1 4 4 4 0 Spc7 kinetochore protein APG6_N PF17675.1 RJW70710.1 - 0.57 10.7 56.4 0.45 11.0 2.4 5.7 3 1 2 5 5 5 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 RJW70710.1 - 0.71 9.9 56.9 0.056 13.5 23.1 5.3 3 2 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rop-like PF05082.13 RJW70710.1 - 2.9 7.8 9.2 4.6 7.1 0.1 4.4 3 1 1 4 4 4 0 Rop-like KASH_CCD PF14662.6 RJW70710.1 - 6.1 6.6 55.4 0.34 10.7 20.3 4.4 4 2 0 4 4 4 0 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 RJW70710.1 - 7.1 5.7 62.2 12 5.0 48.9 4.1 2 1 0 3 3 3 0 HAP1 N-terminal conserved region DUF948 PF06103.11 RJW70710.1 - 8.1 6.8 10.4 44 4.4 0.9 4.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.21 RJW70711.1 - 1.4e-09 37.9 16.2 2.9e-09 36.9 16.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor APG6_N PF17675.1 RJW70711.1 - 0.0007 20.1 2.7 0.0012 19.4 2.7 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region bZIP_2 PF07716.15 RJW70711.1 - 0.0014 18.7 15.2 0.0028 17.7 15.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RJW70711.1 - 0.0057 17.1 8.4 0.013 16.0 8.4 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor HOOK PF05622.12 RJW70711.1 - 0.015 13.5 4.8 0.021 13.0 4.8 1.1 1 0 0 1 1 1 0 HOOK protein FSH1 PF03959.13 RJW70713.1 - 0.1 12.2 0.2 0.27 10.9 0.2 1.7 1 0 0 1 1 1 0 Serine hydrolase (FSH1) SlyX PF04102.12 RJW70713.1 - 0.71 10.5 5.4 10 6.9 0.5 4.9 3 0 0 3 3 3 0 SlyX EGF PF00008.27 RJW70717.1 - 4.6e-58 193.1 277.6 1.1e-08 35.2 7.6 21.7 21 3 0 21 21 21 17 EGF-like domain hEGF PF12661.7 RJW70717.1 - 5.7e-30 102.9 250.9 6.4e-06 26.6 8.5 23.1 22 2 0 22 22 22 14 Human growth factor-like EGF Notch PF00066.17 RJW70717.1 - 1.6e-15 57.2 29.3 1.3e-11 44.7 10.9 11.4 14 2 0 14 14 14 2 LNR domain EGF_CA PF07645.15 RJW70717.1 - 1.3e-14 54.1 68.2 2.3e-07 30.9 7.0 18.3 15 4 4 19 19 19 8 Calcium-binding EGF domain NODP PF07684.12 RJW70717.1 - 3.5e-11 43.1 0.1 2.3e-10 40.5 0.1 2.6 1 0 0 1 1 1 1 NOTCH protein EGF_2 PF07974.13 RJW70717.1 - 8.8e-06 26.0 316.4 0.0033 17.7 8.0 21.3 22 0 0 22 22 22 13 EGF-like domain EGF_3 PF12947.7 RJW70717.1 - 0.012 15.8 3.7 0.012 15.8 3.7 19.9 19 2 1 20 20 20 0 EGF domain Transketolase_N PF00456.21 RJW70718.1 - 3.1e-42 144.7 0.0 5.9e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 RJW70718.1 - 1.9e-34 118.9 0.0 3.1e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RJW70718.1 - 2.5e-32 111.3 0.1 2.8e-31 108.0 0.1 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 RJW70718.1 - 3.1e-09 36.2 0.0 4.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RJW70718.1 - 6.4e-06 25.6 0.0 0.0003 20.1 0.0 2.2 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 RJW70718.1 - 6.5e-05 22.8 0.1 0.00066 19.5 0.1 2.5 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 RJW70718.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain zf-C3HC4 PF00097.25 RJW70719.1 - 0.00013 21.7 11.2 0.00042 20.1 11.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW70719.1 - 0.00016 21.4 11.1 0.00016 21.4 11.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW70719.1 - 0.0006 19.6 11.0 0.0006 19.6 11.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW70719.1 - 0.0011 19.2 12.9 0.0011 19.2 12.9 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 RJW70719.1 - 0.0033 17.3 10.7 0.007 16.2 10.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-met PF12874.7 RJW70719.1 - 0.015 15.6 0.2 0.015 15.6 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-rbx1 PF12678.7 RJW70719.1 - 0.022 15.1 8.8 0.06 13.6 8.8 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RJW70719.1 - 0.05 13.6 7.1 0.22 11.6 7.1 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 RJW70719.1 - 0.29 11.1 13.0 1 9.4 13.0 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RJW70719.1 - 5.8 7.2 14.8 1.9 8.7 9.9 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF1348 PF07080.11 RJW70720.1 - 0.087 12.8 0.4 0.2 11.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) DUF3896 PF13035.6 RJW70720.1 - 1.9 8.7 8.4 5.3 7.3 5.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) CH PF00307.31 RJW70721.1 - 9.5e-44 148.0 0.5 7.9e-22 77.5 0.1 3.8 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW70721.1 - 0.0021 17.9 0.0 1.6 8.6 0.1 2.8 2 0 0 2 2 2 2 CAMSAP CH domain DUF1678 PF07913.11 RJW70721.1 - 0.72 9.6 7.1 12 5.6 0.7 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1678) VAPB_antitox PF02697.14 RJW70721.1 - 3.3 8.6 12.6 14 6.6 0.0 6.0 4 0 0 4 4 4 0 Putative antitoxin DUF3509 PF12021.8 RJW70722.1 - 0.0039 16.9 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) Ribosomal_S21 PF01165.20 RJW70723.1 - 2.8e-11 42.9 0.4 4.5e-11 42.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 Ion_trans PF00520.31 RJW70727.1 - 1.7e-29 102.8 16.9 2.4e-29 102.3 16.9 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 RJW70727.1 - 4e-12 46.3 0.0 9e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain Ion_trans_2 PF07885.16 RJW70727.1 - 6.4e-11 42.1 0.3 6.4e-11 42.1 0.3 2.3 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 RJW70727.1 - 5.7e-08 32.7 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS PF00989.25 RJW70727.1 - 0.0073 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF4484 PF14831.6 RJW70727.1 - 0.079 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Ank_4 PF13637.6 RJW70728.1 - 6.7e-05 23.4 0.1 0.13 12.9 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW70728.1 - 0.00019 21.9 0.1 0.0069 17.0 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) SOCS_box PF07525.16 RJW70728.1 - 0.0098 16.2 2.7 0.0098 16.2 2.7 1.9 2 0 0 2 2 2 1 SOCS box Ank_3 PF13606.6 RJW70728.1 - 0.013 16.0 1.0 1.4 9.7 0.0 4.4 5 0 0 5 5 5 0 Ankyrin repeat Comm PF15957.5 RJW70729.1 - 0.059 13.7 0.2 0.28 11.5 0.2 2.1 1 0 0 1 1 1 0 Commissureless PurA PF04845.13 RJW70730.1 - 1.9e-94 315.1 0.2 2.4e-94 314.8 0.2 1.1 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 RJW70730.1 - 7.9e-07 29.3 0.7 0.26 11.4 0.1 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3276) EFG_C PF00679.24 RJW70730.1 - 0.0096 15.9 0.1 1.1 9.3 0.0 3.0 3 0 0 3 3 3 1 Elongation factor G C-terminus HARE-HTH PF05066.13 RJW70730.1 - 0.029 14.7 0.1 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain Sterol-sensing PF12349.8 RJW70734.1 - 0.02 14.8 0.1 0.06 13.2 0.1 1.8 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation Sarcoglycan_1 PF04790.13 RJW70734.1 - 0.028 13.8 0.9 0.061 12.7 0.9 1.5 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Metallophos_2 PF12850.7 RJW70736.1 - 3.5e-21 76.1 0.0 4.2e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 RJW70736.1 - 5e-05 23.9 0.7 0.08 13.4 0.0 2.5 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase ECH_2 PF16113.5 RJW70739.1 - 1.9e-109 366.2 0.0 2.7e-109 365.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 RJW70739.1 - 7e-18 64.8 0.0 2e-17 63.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF4404 PF14357.6 RJW70739.1 - 0.093 13.4 0.2 0.21 12.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Cadherin PF00028.17 RJW70740.1 - 1.3e-77 256.3 5.3 5.9e-14 52.3 0.0 8.8 8 0 0 8 8 8 8 Cadherin domain Cadherin_2 PF08266.12 RJW70740.1 - 1.2e-11 44.3 0.0 3e-07 30.2 0.0 5.0 4 0 0 4 4 4 1 Cadherin-like Cadherin_3 PF16184.5 RJW70740.1 - 0.015 15.2 5.9 7.2 6.6 0.0 4.8 5 0 0 5 5 5 0 Cadherin-like Comm PF15957.5 RJW70740.1 - 0.077 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Commissureless Cadherin_4 PF17803.1 RJW70740.1 - 0.41 11.3 0.0 0.41 11.3 0.0 4.8 5 0 0 5 5 5 0 Bacterial cadherin-like domain 7tm_1 PF00001.21 RJW70741.1 - 1.1e-43 149.5 6.9 1.4e-43 149.2 4.0 1.9 1 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW70741.1 - 1.6e-13 50.7 2.1 2.8e-13 49.9 2.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RJW70741.1 - 7.4e-06 25.8 17.4 8.8e-06 25.5 15.4 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 RJW70741.1 - 0.00093 18.6 3.8 0.0014 18.0 3.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 RJW70741.1 - 0.0019 18.0 0.3 0.0019 18.0 0.3 1.6 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 RJW70741.1 - 0.0029 17.2 3.2 0.0029 17.2 3.2 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc Acetyltransf_1 PF00583.25 RJW70742.1 - 3.1e-15 56.4 0.0 3.9e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RJW70742.1 - 2.6e-11 43.6 0.1 3.2e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RJW70742.1 - 4.7e-09 36.5 0.0 6.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RJW70742.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 RJW70742.1 - 0.0047 17.6 0.0 0.0064 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RJW70742.1 - 0.0074 16.4 0.0 0.012 15.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 RJW70742.1 - 0.019 14.4 0.1 0.019 14.4 0.1 1.5 2 0 0 2 2 2 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 RJW70742.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Glycoprot_B_PH2 PF17417.2 RJW70742.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.7 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain RAI16-like PF10257.9 RJW70745.1 - 2e-53 181.6 6.1 3.8e-53 180.7 6.1 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF5113 PF17140.4 RJW70745.1 - 0.11 12.3 0.1 0.81 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) RWD PF05773.22 RJW70748.1 - 3.8e-10 40.1 0.0 6.3e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_11 PF17123.5 RJW70748.1 - 0.0055 16.4 6.9 0.0055 16.4 6.9 1.7 2 0 0 2 2 2 1 RING-like zinc finger RINGv PF12906.7 RJW70748.1 - 0.026 14.6 4.0 0.069 13.3 4.0 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING_2 PF13639.6 RJW70748.1 - 0.031 14.6 12.5 0.17 12.2 12.6 2.0 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 RJW70748.1 - 2.8 8.0 12.8 14 5.8 12.8 2.0 1 1 0 1 1 1 0 zinc-RING finger domain DUF3509 PF12021.8 RJW70749.1 - 0.0011 18.7 0.1 0.0029 17.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) RVT_1 PF00078.27 RJW70750.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) dsrm PF00035.26 RJW70751.1 - 2.6e-11 44.1 0.0 5.2e-09 36.7 0.0 3.0 2 0 0 2 2 2 2 Double-stranded RNA binding motif Kunitz_BPTI PF00014.23 RJW70752.1 - 1.3e-13 50.9 6.5 1.7e-13 50.6 6.5 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain SNF2_N PF00176.23 RJW70753.1 - 3.6e-42 144.3 0.0 5.3e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW70753.1 - 1.5e-14 54.3 0.0 2.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW70753.1 - 2.3e-07 31.0 0.0 3.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RJW70753.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2439 PF10382.9 RJW70753.1 - 0.025 14.9 0.1 0.058 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) SWI2_SNF2 PF18766.1 RJW70753.1 - 0.041 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Actin PF00022.19 RJW70754.1 - 4.1e-17 61.9 0.0 9.5e-09 34.3 0.0 2.5 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 RJW70754.1 - 5.4e-10 39.0 0.1 6.9e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Putative actin-like family Hormone_3 PF00159.18 RJW70754.1 - 0.075 13.1 0.2 2 8.5 0.0 2.6 2 0 0 2 2 2 0 Pancreatic hormone peptide RVT_1 PF00078.27 RJW70755.1 - 0.037 13.5 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Nrap_D4 PF17405.2 RJW70756.1 - 1.1e-27 96.8 0.0 1.7e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 RJW70756.1 - 4.6e-22 78.5 0.0 2.3e-18 66.5 0.0 2.3 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 RJW70756.1 - 4.1e-05 23.8 0.0 8.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap_D2 PF17403.2 RJW70756.1 - 0.001 18.8 0.0 0.0029 17.4 0.0 1.9 1 1 0 1 1 1 1 Nrap protein PAP/OAS-like domain DSL PF01414.19 RJW70757.1 - 3.9e-11 43.1 1.5 3.9e-11 43.1 1.5 4.0 4 0 0 4 4 4 1 Delta serrate ligand EGF PF00008.27 RJW70757.1 - 4.5e-06 26.8 13.0 0.00031 21.0 4.6 5.7 6 0 0 6 6 6 3 EGF-like domain hEGF PF12661.7 RJW70757.1 - 3.4e-05 24.3 35.2 0.0065 17.1 0.3 5.5 5 0 0 5 5 5 3 Human growth factor-like EGF EGF_CA PF07645.15 RJW70757.1 - 0.0036 17.5 7.4 0.0036 17.5 7.4 5.3 3 2 2 5 5 5 2 Calcium-binding EGF domain DUF4381 PF14316.6 RJW70757.1 - 0.33 11.2 0.5 0.56 10.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EGF_3 PF12947.7 RJW70757.1 - 0.68 10.2 24.6 0.28 11.4 3.2 3.8 3 0 0 3 3 3 0 EGF domain Plasmod_Pvs28 PF06247.11 RJW70757.1 - 2.6 8.4 22.2 0.28 11.5 4.0 4.0 3 1 1 4 4 4 0 Pvs28 EGF domain EGF_2 PF07974.13 RJW70757.1 - 3.4 8.1 43.4 0.14 12.6 1.2 5.6 5 0 0 5 5 5 0 EGF-like domain cEGF PF12662.7 RJW70757.1 - 4.6 7.3 16.3 0.15 12.1 1.6 4.0 4 0 0 4 4 4 0 Complement Clr-like EGF-like PKcGMP_CC PF16808.5 RJW70758.1 - 0.28 11.1 5.5 7.5 6.5 0.1 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Glyco_transf_15 PF01793.16 RJW70758.1 - 0.73 9.0 5.8 1.3 8.2 5.8 1.4 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase WbqC PF08889.11 RJW70758.1 - 0.95 9.3 6.1 0.92 9.4 4.8 1.5 1 1 0 1 1 1 0 WbqC-like protein family Urocanase PF01175.18 RJW70758.1 - 4.8 6.8 8.3 6.9 6.3 1.4 2.3 1 1 1 2 2 2 0 Urocanase Rossmann-like domain Homeobox_KN PF05920.11 RJW70759.1 - 1.5e-15 56.8 0.2 4.5e-15 55.3 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RJW70759.1 - 3.3e-07 30.1 1.4 6.7e-07 29.1 1.4 1.6 1 0 0 1 1 1 1 Homeodomain UDG PF03167.19 RJW70760.1 - 7.7e-21 74.7 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily MRP-S35 PF10246.9 RJW70760.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 Ribosomal_L28e PF01778.17 RJW70761.1 - 1.2e-31 109.8 0.5 1.2e-31 109.8 0.5 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 RJW70761.1 - 4.4e-18 65.7 28.6 1.3e-17 64.2 28.6 1.8 1 1 0 1 1 1 1 Mak16 protein C-terminal region Na_trans_assoc PF06512.13 RJW70761.1 - 5.3 7.3 13.7 9 6.5 13.7 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated 7tm_1 PF00001.21 RJW70762.1 - 1.1e-15 57.6 0.0 1.2e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Peptidase_M41 PF01434.18 RJW70763.1 - 8.8e-57 192.0 0.0 1.5e-56 191.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 RJW70763.1 - 4.4e-41 140.4 0.0 1.2e-40 138.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW70763.1 - 7.3e-10 38.5 0.1 8.3e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 RJW70763.1 - 4.3e-06 26.8 0.0 1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RJW70763.1 - 5.2e-05 23.0 0.0 0.00018 21.3 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RJW70763.1 - 0.00055 20.4 2.0 0.0074 16.7 0.2 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 RJW70763.1 - 0.0013 19.0 0.2 0.056 13.7 0.2 2.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 RJW70763.1 - 0.004 16.4 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 RJW70763.1 - 0.0072 16.4 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RJW70763.1 - 0.012 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 RJW70763.1 - 0.029 13.8 0.1 0.071 12.5 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RJW70763.1 - 0.041 14.0 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 RJW70763.1 - 0.054 13.6 0.0 0.2 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 RJW70763.1 - 0.062 13.2 0.5 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 RJW70763.1 - 0.066 13.8 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RJW70763.1 - 0.13 11.7 0.0 0.43 10.1 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 RJW70763.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DWNN PF08783.11 RJW70764.1 - 1.4e-21 76.6 0.3 3.4e-21 75.3 0.3 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_3 PF13917.6 RJW70764.1 - 0.00019 21.3 0.1 0.00046 20.1 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RJW70764.1 - 0.00037 20.3 7.5 0.00037 20.3 7.5 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_3 PF13920.6 RJW70764.1 - 0.0018 18.1 7.3 0.0018 18.1 7.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW70764.1 - 0.0064 16.3 10.2 0.0064 16.3 10.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RJW70764.1 - 0.011 15.9 10.7 0.023 14.8 10.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCHC PF00098.23 RJW70764.1 - 0.017 15.2 3.2 0.017 15.2 3.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4 PF00097.25 RJW70764.1 - 0.024 14.5 9.6 0.053 13.4 9.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW70764.1 - 0.026 14.9 9.5 0.065 13.6 9.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 RJW70764.1 - 0.049 13.7 7.4 0.11 12.5 7.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 RJW70764.1 - 0.9 9.5 5.4 1.9 8.4 5.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-LITAF-like PF10601.9 RJW70764.1 - 6.8 7.0 10.1 50 4.2 10.1 2.4 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain ALMT PF11744.8 RJW70764.1 - 7.7 5.2 9.3 18 4.0 9.3 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter ODC_AZ PF02100.17 RJW70768.1 - 6.1e-05 23.0 0.0 9.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Aph-1 PF06105.12 RJW70769.1 - 1.5e-62 211.0 11.6 1.9e-62 210.7 11.6 1.0 1 0 0 1 1 1 1 Aph-1 protein Glyco_transf_7N PF13733.6 RJW70770.1 - 3e-65 217.9 0.0 5.1e-34 116.8 0.0 2.5 2 0 0 2 2 2 2 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RJW70770.1 - 2.7e-45 151.9 0.9 2.4e-21 75.2 0.1 2.5 2 0 0 2 2 2 2 N-terminal domain of galactosyltransferase DUF2484 PF10658.9 RJW70770.1 - 0.16 12.3 4.4 3.9 7.9 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) Glyco_transf_7C PF02709.14 RJW70772.1 - 7.2e-22 76.8 0.1 1.3e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 RJW70772.1 - 1e-05 25.2 0.6 1.9e-05 24.4 0.6 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Nop14 PF04147.12 RJW70772.1 - 0.005 15.1 10.0 0.0053 15.1 10.0 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RJW70772.1 - 0.022 14.2 14.1 0.027 13.9 14.1 1.1 1 0 0 1 1 1 0 SDA1 Astro_capsid_p PF12226.8 RJW70772.1 - 0.025 13.7 8.4 0.03 13.5 8.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 RJW70772.1 - 0.62 8.3 10.7 0.68 8.2 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 RJW70772.1 - 1 8.1 5.8 1.1 7.9 5.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pkinase_C PF00433.24 RJW70773.1 - 0.036 14.8 0.0 0.048 14.4 0.0 1.4 1 1 0 1 1 1 0 Protein kinase C terminal domain 7tm_1 PF00001.21 RJW70774.1 - 6e-19 68.4 12.6 1.1e-18 67.5 12.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Peptidase_C12 PF01088.21 RJW70775.1 - 4.3e-20 72.4 0.0 6.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AsnA PF03590.15 RJW70776.1 - 2.2e-98 328.5 0.9 2.8e-98 328.2 0.9 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.20 RJW70776.1 - 0.016 14.3 0.9 0.033 13.3 0.9 1.6 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Virulence_fact PF13769.6 RJW70776.1 - 0.34 11.2 3.9 0.23 11.7 1.0 2.3 3 1 0 3 3 3 0 Virulence factor MWFE PF15879.5 RJW70776.1 - 2.5 8.3 3.7 2.1 8.6 2.0 1.8 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF4404 PF14357.6 RJW70777.1 - 0.051 14.2 0.3 19 6.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) PUF PF00806.19 RJW70777.1 - 0.19 11.5 0.0 3.2 7.6 0.0 2.7 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat Guanylate_cyc PF00211.20 RJW70779.1 - 6.4e-40 136.7 1.6 3.2e-25 88.8 0.2 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF4381 PF14316.6 RJW70779.1 - 0.033 14.4 1.2 0.13 12.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Metallophos PF00149.28 RJW70782.1 - 1.4e-37 130.1 0.1 2e-37 129.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 RJW70785.1 - 5.7e-61 206.2 0.0 1.3e-60 205.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW70785.1 - 1.6e-49 168.5 0.0 3.5e-49 167.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PKK PF12474.8 RJW70785.1 - 1.5e-06 28.4 41.4 4.8e-06 26.8 11.4 5.5 5 1 0 5 5 5 2 Polo kinase kinase APH PF01636.23 RJW70785.1 - 0.065 13.1 1.8 0.13 12.1 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Nbl1_Borealin_N PF10444.9 RJW70785.1 - 1.6 8.4 11.8 0.026 14.2 2.2 3.0 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF725 PF05267.12 RJW70785.1 - 2.7 8.0 7.6 0.87 9.6 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF725) Drf_FH3 PF06367.16 RJW70786.1 - 4.3e-22 78.7 0.4 1e-21 77.4 0.4 1.6 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 RJW70786.1 - 4.1e-10 39.5 1.3 1e-09 38.3 1.3 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain FH2 PF02181.23 RJW70786.1 - 0.00014 21.2 5.2 0.083 12.0 0.0 3.1 3 0 0 3 3 3 2 Formin Homology 2 Domain HIP1_clath_bdg PF16515.5 RJW70786.1 - 0.017 15.8 4.6 0.074 13.7 4.3 2.2 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 RJW70786.1 - 0.79 8.7 4.9 1.4 7.9 4.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 RJW70786.1 - 2.5 8.1 8.2 1.3 9.1 2.0 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC1 PF03109.16 RJW70788.1 - 8.2e-30 103.4 0.0 1.4e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family MEA1 PF06910.11 RJW70788.1 - 8.4e-23 81.4 0.0 1.8e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) Guanylate_cyc PF00211.20 RJW70789.1 - 2e-93 311.1 0.3 1.3e-48 165.1 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF5554 PF17709.1 RJW70789.1 - 0.053 13.6 0.1 0.31 11.2 0.1 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5554) DUF5580 PF17743.1 RJW70790.1 - 0.078 11.5 0.7 0.11 11.1 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Elf1 PF05129.13 RJW70791.1 - 2.7e-29 101.0 1.3 3e-29 100.9 1.3 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-RING_11 PF17123.5 RJW70791.1 - 0.02 14.6 1.3 0.2 11.4 0.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger Lar_restr_allev PF14354.6 RJW70791.1 - 0.025 15.0 0.5 0.032 14.6 0.5 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-RING_2 PF13639.6 RJW70791.1 - 0.063 13.6 2.7 0.99 9.8 0.1 2.3 2 0 0 2 2 2 0 Ring finger domain zf-Di19 PF05605.12 RJW70791.1 - 0.38 11.1 4.0 3.2 8.1 4.0 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding CAF1A PF12253.8 RJW70793.1 - 1.7e-24 85.8 10.5 1.7e-24 85.8 10.5 3.4 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A Chorismate_synt PF01264.21 RJW70793.1 - 0.33 9.6 0.7 0.55 8.9 0.7 1.3 1 0 0 1 1 1 0 Chorismate synthase CAF-1_p150 PF11600.8 RJW70793.1 - 0.86 9.3 64.0 0.017 14.8 53.8 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.17 RJW70793.1 - 1.1 9.4 5.0 1.3 9.2 3.0 2.1 2 0 0 2 2 2 0 DDHD domain Borrelia_P83 PF05262.11 RJW70793.1 - 1.3 7.5 26.4 1.6 7.1 25.5 1.5 2 0 0 2 2 2 0 Borrelia P83/100 protein TSC22 PF01166.18 RJW70794.1 - 9.5e-05 22.6 0.8 0.00014 22.1 0.8 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family K-box PF01486.17 RJW70794.1 - 0.0039 17.3 0.5 0.0053 16.9 0.5 1.3 1 0 0 1 1 1 1 K-box region bZIP_1 PF00170.21 RJW70794.1 - 0.0057 16.7 2.2 0.012 15.7 2.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor MAD PF05557.13 RJW70794.1 - 0.0059 15.0 0.7 0.0059 15.0 0.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Herpes_BLRF2 PF05812.12 RJW70794.1 - 0.0061 16.7 1.1 0.0096 16.0 1.1 1.3 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein TPR_MLP1_2 PF07926.12 RJW70794.1 - 0.0063 16.6 1.0 0.0082 16.2 1.0 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein YabA PF06156.13 RJW70794.1 - 0.014 16.1 2.1 0.02 15.5 1.9 1.5 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 RJW70794.1 - 0.015 15.7 3.3 0.028 14.8 3.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 RJW70794.1 - 0.022 14.5 3.4 0.036 13.8 3.1 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF2381 PF09544.10 RJW70794.1 - 0.025 14.1 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) TolA_bind_tri PF16331.5 RJW70794.1 - 0.036 14.2 2.0 0.061 13.4 2.0 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation Spc7 PF08317.11 RJW70794.1 - 0.068 12.0 1.8 0.071 12.0 1.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RNA_pol_Rpb2_2 PF04561.14 RJW70794.1 - 0.13 11.9 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 APC_N_CC PF16689.5 RJW70794.1 - 0.24 11.5 3.8 0.39 10.8 2.5 1.9 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain bZIP_2 PF07716.15 RJW70794.1 - 0.25 11.5 4.0 0.49 10.5 4.0 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Asn_synthase PF00733.21 RJW70795.1 - 2.8e-12 47.0 0.6 1.8e-09 37.7 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase HLH PF00010.26 RJW70796.1 - 1.4e-11 44.2 0.0 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tctex-1 PF03645.13 RJW70797.1 - 5e-12 46.0 0.3 1.5e-11 44.4 0.2 1.9 2 0 0 2 2 2 1 Tctex-1 family RVT_1 PF00078.27 RJW70798.1 - 1.4e-06 28.0 0.2 1.4e-05 24.7 0.2 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Saccharop_dh_N PF04455.12 RJW70798.1 - 0.14 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region DUF4262 PF14081.6 RJW70798.1 - 0.15 12.2 0.0 1.3 9.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) Pkinase PF00069.25 RJW70801.1 - 3.4e-46 157.8 0.0 4.2e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW70801.1 - 5.1e-21 75.1 0.0 7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW70801.1 - 0.00012 21.1 0.0 0.00022 20.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Galactosyl_T PF01762.21 RJW70802.1 - 1.5e-45 155.5 0.0 2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Tim29 PF10171.9 RJW70803.1 - 2.3e-32 111.8 0.1 1.4e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 Translocase of the Inner Mitochondrial membrane 29 Vhr1 PF04001.13 RJW70803.1 - 0.083 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Transcription factor Vhr1 DUF4729 PF15866.5 RJW70805.1 - 0.031 13.6 4.0 1 8.6 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4729) FOXP-CC PF16159.5 RJW70805.1 - 0.037 14.7 1.9 0.33 11.6 0.1 2.7 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 RJW70805.1 - 0.044 13.9 0.2 1.1 9.4 0.0 2.5 2 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2 PF00096.26 RJW70805.1 - 0.046 14.2 10.7 0.23 12.0 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 RJW70805.1 - 0.15 12.8 2.0 0.27 11.9 2.0 1.4 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats 53-BP1_Tudor PF09038.10 RJW70806.1 - 9.1e-05 22.4 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor TFIIIC_sub6 PF10419.9 RJW70808.1 - 1.1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Forkhead PF00250.18 RJW70809.1 - 8.3e-34 115.7 0.0 1.5e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Exo_endo_phos PF03372.23 RJW70811.1 - 1.9e-12 47.2 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA_4 PF14555.6 RJW70811.1 - 9.2e-08 31.8 0.0 2.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 RJW70811.1 - 0.095 12.4 0.3 0.095 12.4 0.3 1.8 2 0 0 2 2 2 0 TAP C-terminal domain Galactosyl_T PF01762.21 RJW70814.1 - 1.7e-36 125.9 0.0 4.8e-36 124.4 0.0 1.7 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 RJW70814.1 - 0.00035 20.1 0.0 0.00054 19.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Pecanex_C PF05041.15 RJW70814.1 - 0.044 13.3 0.1 0.074 12.6 0.1 1.3 1 0 0 1 1 1 0 Pecanex protein (C-terminus) ArfGap PF01412.18 RJW70816.1 - 4.5e-31 107.3 1.5 5.9e-31 107.0 0.1 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf GxDLY PF14607.6 RJW70816.1 - 0.09 12.6 1.0 2.2 8.0 0.2 2.4 2 0 0 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type LCE6A PF15858.5 RJW70818.1 - 2.3 9.0 5.4 4.6 8.1 2.1 2.3 1 1 1 2 2 2 0 Late cornified envelope protein 6A family Ribosomal_S2 PF00318.20 RJW70819.1 - 2.5e-37 128.2 0.0 9.7e-18 64.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 cwf18 PF08315.12 RJW70821.1 - 1.6e-33 116.2 3.3 2.7e-33 115.5 3.3 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Solute_trans_a PF03619.16 RJW70822.1 - 1.6e-68 231.1 13.7 2e-68 230.8 13.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha HEAT PF02985.22 RJW70823.1 - 2.1e-14 52.4 10.5 0.0014 18.8 0.2 7.0 8 0 0 8 8 8 3 HEAT repeat CLASP_N PF12348.8 RJW70823.1 - 1e-08 35.1 0.2 0.0006 19.4 0.0 2.8 3 0 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 RJW70823.1 - 3e-05 24.4 0.1 0.0053 17.2 0.1 4.1 2 1 2 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 RJW70823.1 - 0.00045 20.5 0.1 0.15 12.5 0.1 4.0 4 2 1 5 5 5 2 HEAT repeats MMS19_N PF14500.6 RJW70823.1 - 0.0035 17.0 0.2 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 Dos2-interacting transcription regulator of RNA-Pol-II IFRD PF05004.13 RJW70823.1 - 0.0058 15.8 0.1 12 4.8 0.0 3.3 3 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 RJW70823.1 - 0.0064 16.1 0.1 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 Tti2 family Cnd1 PF12717.7 RJW70823.1 - 0.01 15.9 2.3 6.3 6.8 0.0 3.9 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 RJW70823.1 - 0.012 16.0 0.2 13 6.2 0.0 4.3 2 1 2 4 4 4 0 TAF6 C-terminal HEAT repeat domain Cohesin_HEAT PF12765.7 RJW70823.1 - 0.035 14.4 0.2 39 4.7 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 RJW70823.1 - 0.12 10.9 1.5 15 4.0 0.1 3.0 2 1 1 3 3 3 0 Adaptin N terminal region DNA_pol3_delta2 PF13177.6 RJW70824.1 - 7.4e-14 51.9 1.1 7.9e-13 48.5 1.1 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 RJW70824.1 - 4.2e-06 27.1 0.0 1.1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 RJW70824.1 - 1.6e-05 25.3 0.1 3.9e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 RJW70824.1 - 0.0003 21.1 0.0 0.001 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 RJW70824.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DEAD PF00270.29 RJW70824.1 - 0.0045 16.8 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 RJW70824.1 - 0.032 13.0 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 RJW70824.1 - 0.059 13.6 0.2 0.34 11.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.17 RJW70827.1 - 3.6e-31 108.4 0.0 2.3e-30 105.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW70827.1 - 6.9e-25 87.9 0.0 1.2e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RVT_1 PF00078.27 RJW70827.1 - 0.00099 18.7 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_fungal PF17667.1 RJW70827.1 - 0.0028 16.5 0.0 0.0044 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RJW70827.1 - 0.056 13.4 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TMEM154 PF15102.6 RJW70827.1 - 0.22 11.4 0.0 0.56 10.1 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family RAWUL PF16207.5 RJW70832.1 - 5e-11 43.1 0.1 1e-10 42.1 0.1 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Coilin_N PF15862.5 RJW70832.1 - 0.024 14.4 0.3 0.21 11.4 0.0 2.4 3 0 0 3 3 3 0 Coilin N-terminus Atg8 PF02991.16 RJW70832.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like DUF1195 PF06708.11 RJW70834.1 - 0.026 14.3 0.1 0.037 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Cadherin PF00028.17 RJW70835.1 - 1.4e-63 211.3 2.7 2.8e-11 43.7 0.0 10.0 7 4 1 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 RJW70835.1 - 2.8e-07 30.3 0.0 0.00063 19.5 0.0 4.6 5 0 0 5 5 5 1 Cadherin-like RET_CLD1 PF17756.1 RJW70835.1 - 0.011 16.1 0.0 0.16 12.2 0.0 2.7 2 0 0 2 2 2 0 RET Cadherin like domain 1 Cadherin_3 PF16184.5 RJW70835.1 - 1.3 9.1 5.4 31 4.6 0.0 5.3 7 1 0 7 7 7 0 Cadherin-like Cpn60_TCP1 PF00118.24 RJW70837.1 - 5.2e-19 68.2 0.0 8.3e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 RJW70837.1 - 1.7e-16 60.1 14.0 5.2e-16 58.5 14.0 1.9 1 0 0 1 1 1 1 FYVE zinc finger DEP PF00610.21 RJW70837.1 - 1.9e-05 24.6 0.0 4.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) fn3 PF00041.21 RJW70839.1 - 5.6e-40 135.6 47.9 0.0021 18.4 0.3 26.4 28 0 0 28 28 28 11 Fibronectin type III domain HECW_N PF16562.5 RJW70839.1 - 6.5e-06 26.0 0.0 27 4.6 0.0 7.8 8 0 0 8 8 8 2 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 CMV_1a_C PF12503.8 RJW70839.1 - 0.013 15.4 0.0 68 3.6 0.0 6.5 8 0 0 8 8 8 0 Cucumber mosaic virus 1a protein C terminal DUF1386 PF07138.11 RJW70839.1 - 0.16 11.2 0.4 14 4.8 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1386) GCM PF03615.15 RJW70842.1 - 5.1e-66 220.9 2.0 1e-65 219.9 2.0 1.5 1 0 0 1 1 1 1 GCM motif protein Proteasome PF00227.26 RJW70843.1 - 1.3e-62 210.6 0.0 1.9e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RJW70843.1 - 4.4e-11 42.2 0.0 7.8e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ubiquitin_4 PF18036.1 RJW70845.1 - 8.3e-11 41.8 0.9 0.0017 18.4 0.0 3.5 4 0 0 4 4 4 3 Ubiquitin-like domain DNase_II PF03265.15 RJW70846.1 - 8.2e-16 58.2 0.0 9e-14 51.5 0.0 2.2 1 1 1 2 2 2 2 Deoxyribonuclease II PCI PF01399.27 RJW70849.1 - 5.9e-11 42.8 0.0 1.3e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain DAO PF01266.24 RJW70850.1 - 1.5e-21 77.4 0.0 2e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Neur_chan_LBD PF02931.23 RJW70852.1 - 8.2e-56 188.8 0.6 1.7e-55 187.8 0.6 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW70852.1 - 1.4e-21 77.7 1.3 6.7e-19 68.9 0.2 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region ASC PF00858.24 RJW70853.1 - 3.7e-49 167.9 0.0 4.5e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Cystatin PF00031.21 RJW70854.1 - 6.2e-07 29.6 0.0 7.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain Tautomerase PF01361.21 RJW70854.1 - 0.04 13.9 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme Tautomerase_2 PF14552.6 RJW70854.1 - 0.049 13.7 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Tautomerase enzyme Dynamin_M PF01031.20 RJW70856.1 - 4.2e-95 318.2 1.3 4.2e-95 318.2 1.3 1.6 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 RJW70856.1 - 1.1e-23 83.1 1.8 2.5e-23 82.0 1.8 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 RJW70856.1 - 2.8e-09 37.4 0.4 5.1e-09 36.6 0.4 1.4 1 0 0 1 1 1 1 PH domain DASH_Duo1 PF08651.10 RJW70856.1 - 0.064 13.0 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 Fer4 PF00037.27 RJW70857.1 - 3e-14 52.1 17.5 1.5e-08 34.1 4.5 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 RJW70857.1 - 8.6e-13 48.7 10.5 1.5e-12 47.8 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 RJW70857.1 - 5.1e-11 43.3 6.2 3.5e-05 24.6 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 RJW70857.1 - 4.1e-10 39.6 3.5 0.00016 21.7 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 RJW70857.1 - 1.1e-08 35.0 21.1 4.5e-06 26.7 12.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 RJW70857.1 - 1.3e-08 34.9 10.3 2.2e-08 34.1 10.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 RJW70857.1 - 1.6e-07 31.7 18.4 0.00021 21.7 11.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 RJW70857.1 - 2.6e-07 30.4 17.8 0.00034 20.5 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 RJW70857.1 - 8.5e-07 28.7 12.1 0.0024 17.9 2.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 RJW70857.1 - 3.7e-06 27.0 11.1 0.00031 21.0 2.0 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 RJW70857.1 - 0.00039 20.9 11.6 0.032 14.8 12.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 RJW70857.1 - 0.0033 17.6 5.1 0.49 10.7 0.3 2.5 2 1 1 3 3 3 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 RJW70857.1 - 0.0088 16.6 14.5 0.52 10.9 2.5 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 RJW70857.1 - 0.035 14.3 8.7 0.93 9.7 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 RJW70857.1 - 0.11 13.5 16.3 0.3 12.1 4.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 RJW70857.1 - 0.25 11.5 5.8 1.1 9.4 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 RJW70857.1 - 0.79 10.6 12.0 2.5 9.0 1.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain CLPTM1 PF05602.12 RJW70858.1 - 3.9e-74 250.2 0.0 4.9e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 RJW70858.1 - 0.72 9.7 4.2 4.3 7.2 0.0 2.9 3 0 0 3 3 3 0 PQ loop repeat TPR_14 PF13428.6 RJW70859.1 - 2.8e-14 52.6 28.1 0.82 10.7 0.1 11.8 7 3 5 12 12 12 5 Tetratricopeptide repeat Suf PF05843.14 RJW70859.1 - 4e-11 43.4 3.0 9.1e-06 25.9 0.3 4.7 4 1 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_2 PF07719.17 RJW70859.1 - 3.5e-08 33.0 25.0 0.13 12.5 0.0 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RJW70859.1 - 3.1e-06 27.2 9.1 0.13 12.2 0.4 6.7 6 1 1 7 7 7 1 Mad3/BUB1 homology region 1 NRDE-2 PF08424.10 RJW70859.1 - 3.3e-06 26.5 13.1 0.018 14.1 0.1 7.0 3 2 1 5 5 5 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 RJW70859.1 - 3e-05 24.5 14.5 0.22 12.1 0.0 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 RJW70859.1 - 5.7e-05 23.3 17.6 3.6 7.9 0.3 6.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW70859.1 - 0.00019 21.4 15.9 1.3 9.5 0.1 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat SNAP PF14938.6 RJW70859.1 - 0.023 14.1 6.9 0.62 9.4 0.1 3.9 2 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 RJW70859.1 - 0.063 13.7 11.4 30 5.3 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW70859.1 - 0.077 13.7 16.2 15 6.5 0.1 7.1 8 1 0 8 8 7 0 Tetratricopeptide repeat HhH-GPD PF00730.25 RJW70859.1 - 0.15 12.5 0.1 0.57 10.7 0.1 2.0 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein TPR_1 PF00515.28 RJW70859.1 - 0.17 11.7 13.6 0.48 10.3 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 RJW70859.1 - 0.19 12.0 3.0 66 4.1 0.0 4.9 6 0 0 6 6 4 0 PPR repeat Cystatin PF00031.21 RJW70860.1 - 2.1e-06 27.9 0.1 3.4e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Cystatin domain Abhydrolase_8 PF06259.12 RJW70861.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Histone_H2A_C PF16211.5 RJW70863.1 - 8.2e-21 73.5 1.4 1.3e-20 72.8 1.4 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 RJW70863.1 - 2.6e-15 56.9 0.0 3.2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RJW70863.1 - 2.5e-06 27.7 0.0 3.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3947 PF13135.6 RJW70866.1 - 0.044 14.0 0.5 0.15 12.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) ELP6 PF09807.9 RJW70867.1 - 4e-06 26.4 0.0 7.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Elongation complex protein 6 SRR1 PF07985.12 RJW70869.1 - 0.14 12.3 0.4 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 SRR1 F5_F8_type_C PF00754.25 RJW70871.1 - 6.3e-28 97.4 0.3 1.1e-27 96.7 0.3 1.4 1 0 0 1 1 1 1 F5/8 type C domain Rsm1 PF08600.10 RJW70871.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Rsm1-like TRAPP PF04051.16 RJW70872.1 - 7.4e-32 110.1 0.0 8.7e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Lantibiotic_a PF14867.6 RJW70872.1 - 0.074 12.8 1.2 0.12 12.2 1.2 1.2 1 0 0 1 1 1 0 Lantibiotic alpha EF-hand_7 PF13499.6 RJW70873.1 - 5.7e-09 36.3 0.9 1.2e-08 35.3 0.9 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW70873.1 - 7.3e-08 31.4 0.2 0.016 14.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 RJW70873.1 - 7e-07 28.5 0.8 0.02 14.4 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW70873.1 - 9.9e-07 28.5 1.0 0.026 14.4 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW70873.1 - 1.5e-05 24.5 0.3 0.034 14.1 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RJW70873.1 - 0.00013 22.2 0.5 0.00021 21.6 0.5 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Ribos_L4_asso_C PF14374.6 RJW70873.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 2 0 0 2 2 2 0 60S ribosomal protein L4 C-terminal domain RRN3 PF05327.11 RJW70875.1 - 3.2e-33 115.1 1.1 1e-32 113.4 1.1 1.6 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 PIGA PF08288.12 RJW70876.1 - 2.3e-39 133.8 0.2 5.1e-39 132.8 0.2 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 RJW70876.1 - 6.2e-33 114.2 0.4 1.7e-32 112.7 0.4 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 RJW70876.1 - 1.2e-16 60.8 0.0 2.2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RJW70876.1 - 4e-16 59.7 0.0 9.2e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 RJW70876.1 - 8.9e-16 58.7 0.0 3.8e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 RJW70876.1 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 RJW70876.1 - 0.0023 17.7 0.1 0.0053 16.5 0.0 1.7 1 1 1 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 RJW70876.1 - 0.21 12.0 0.0 0.21 12.0 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferases group 1 HU-HIG PF18291.1 RJW70876.1 - 0.22 11.6 0.0 4.1 7.5 0.0 2.3 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Tex_YqgF PF16921.5 RJW70881.1 - 1.5e-37 128.9 0.0 2.6e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Tex protein YqgF-like domain Tex_N PF09371.10 RJW70881.1 - 1.4e-32 112.8 0.0 2.5e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_3 PF12836.7 RJW70881.1 - 1.2e-22 79.9 0.0 2.9e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 RJW70881.1 - 1.5e-11 45.0 0.0 5.5e-11 43.2 0.0 2.0 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 RJW70881.1 - 9e-07 29.1 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain HHH_7 PF14635.6 RJW70881.1 - 1.8e-05 25.0 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 RJW70881.1 - 0.00027 20.7 0.0 0.00059 19.6 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH PF00633.23 RJW70881.1 - 0.00049 19.8 0.0 0.024 14.5 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 RJW70881.1 - 0.24 12.0 1.0 3.3 8.4 0.3 3.3 3 1 1 4 4 4 0 Helix-hairpin-helix domain Pkinase_Tyr PF07714.17 RJW70883.1 - 1.4e-76 257.2 0.0 1.6e-74 250.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW70883.1 - 4.7e-36 124.5 0.0 4e-35 121.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Recep_L_domain PF01030.24 RJW70883.1 - 5.7e-32 110.2 0.0 4.4e-15 55.8 0.0 3.1 2 1 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.6 RJW70883.1 - 4e-22 78.4 108.1 6.3e-07 29.3 3.7 8.6 6 2 3 9 9 9 7 Growth factor receptor domain IV Furin-like PF00757.20 RJW70883.1 - 1.2e-18 67.4 111.0 3.8e-11 43.1 39.1 7.4 3 3 3 6 6 6 5 Furin-like cysteine rich region Kdo PF06293.14 RJW70883.1 - 0.35 10.2 1.2 0.5 9.7 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.23 RJW70884.1 - 9.2e-41 140.3 0.0 1.2e-40 139.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW70884.1 - 4.7e-11 43.2 0.2 2.9e-09 37.4 0.1 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RJW70884.1 - 0.0047 17.5 0.0 0.91 10.2 0.0 2.8 3 0 0 3 3 3 1 Aspartyl protease DUF155 PF02582.14 RJW70884.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 gag-asp_proteas PF13975.6 RJW70884.1 - 0.14 12.7 0.0 23 5.7 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease MGAT2 PF05060.14 RJW70885.1 - 2.9e-31 108.8 0.1 3.5e-31 108.6 0.1 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) AAA_5 PF07728.14 RJW70886.1 - 1.1e-113 375.3 0.0 1.1e-22 80.5 0.0 7.6 7 0 0 7 7 7 7 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 RJW70886.1 - 8e-44 148.2 5.8 9.2e-15 54.8 0.1 6.2 6 0 0 6 6 5 4 Midasin AAA lid domain AAA_3 PF07726.11 RJW70886.1 - 7.7e-23 80.8 0.0 2.6e-08 33.8 0.0 6.8 8 0 0 8 8 6 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 RJW70886.1 - 1.5e-22 79.7 0.0 9.7e-22 77.1 0.0 2.5 1 0 0 1 1 1 1 Midasin AAA lid domain AAA PF00004.29 RJW70886.1 - 1.1e-21 77.6 0.2 0.00014 22.3 0.0 6.7 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RJW70886.1 - 1.5e-21 76.8 0.1 0.00025 20.6 0.0 6.1 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_16 PF13191.6 RJW70886.1 - 9.6e-21 74.9 15.9 0.0029 18.0 0.1 8.8 7 1 0 7 7 6 5 AAA ATPase domain AAA_22 PF13401.6 RJW70886.1 - 2.5e-15 56.9 5.6 0.026 14.8 0.0 7.6 7 0 0 7 7 6 4 AAA domain Dynein_heavy PF03028.15 RJW70886.1 - 6.5e-14 52.0 0.0 0.01 15.9 0.0 6.9 7 0 0 7 7 5 3 Dynein heavy chain region D6 P-loop domain TsaE PF02367.17 RJW70886.1 - 5.9e-12 45.7 1.5 0.72 9.9 0.0 6.7 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 RJW70886.1 - 2.2e-11 43.8 0.0 0.042 13.6 0.0 6.3 7 0 0 7 7 7 3 AAA domain Sigma54_activ_2 PF14532.6 RJW70886.1 - 5.2e-10 39.6 0.1 0.0024 18.0 0.0 5.4 5 0 0 5 5 5 1 Sigma-54 interaction domain ABC_tran PF00005.27 RJW70886.1 - 1.4e-09 38.6 0.8 1.1 9.8 0.0 6.4 6 0 0 6 6 6 1 ABC transporter Sigma54_activat PF00158.26 RJW70886.1 - 1.4e-09 37.8 0.1 0.2 11.4 0.0 6.0 7 0 0 7 7 5 2 Sigma-54 interaction domain AAA_6 PF12774.7 RJW70886.1 - 1.8e-09 37.0 0.4 0.13 11.2 0.0 6.9 8 0 0 8 8 7 1 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 RJW70886.1 - 1.9e-08 34.9 4.9 1.6 9.3 0.0 6.9 7 0 0 7 7 6 1 AAA domain RsgA_GTPase PF03193.16 RJW70886.1 - 8.5e-08 32.3 0.2 4.8 7.1 0.0 5.5 6 0 0 6 6 5 0 RsgA GTPase AAA_25 PF13481.6 RJW70886.1 - 9.6e-08 31.8 1.8 1.9 8.0 0.0 5.8 6 0 0 6 6 5 2 AAA domain AAA_8 PF12780.7 RJW70886.1 - 1.2e-07 31.4 0.1 3.1 7.0 0.0 5.5 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 AAA_14 PF13173.6 RJW70886.1 - 1.2e-07 31.9 0.0 2.2 8.4 0.0 6.2 6 0 0 6 6 6 2 AAA domain RNA_helicase PF00910.22 RJW70886.1 - 4e-07 30.4 0.6 15 6.0 0.0 6.1 6 0 0 6 6 6 0 RNA helicase RuvB_N PF05496.12 RJW70886.1 - 4.4e-07 29.8 0.2 1.3 8.8 0.0 5.8 6 0 0 6 6 6 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 RJW70886.1 - 2.7e-06 26.8 0.1 1.2 8.4 0.0 5.3 6 0 0 6 6 6 1 Zeta toxin DUF815 PF05673.13 RJW70886.1 - 4e-06 26.2 0.7 0.12 11.5 0.0 4.7 6 0 0 6 6 6 2 Protein of unknown function (DUF815) T2SSE PF00437.20 RJW70886.1 - 5.4e-06 25.7 0.1 6.1 5.8 0.0 5.5 6 0 0 6 6 6 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 RJW70886.1 - 1.2e-05 24.8 6.6 24 4.2 0.1 8.0 9 1 0 9 9 8 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RJW70886.1 - 1.4e-05 25.1 1.1 5.8 6.8 0.0 6.4 7 0 0 7 7 6 0 NACHT domain Rad17 PF03215.15 RJW70886.1 - 2.6e-05 24.2 7.0 7.5 6.4 0.0 5.4 5 0 0 5 5 5 0 Rad17 P-loop domain AAA_19 PF13245.6 RJW70886.1 - 6e-05 23.4 3.9 3.5 7.9 0.0 5.6 5 0 0 5 5 4 1 AAA domain Roc PF08477.13 RJW70886.1 - 7.6e-05 22.9 0.2 18 5.6 0.0 4.7 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 RJW70886.1 - 7.7e-05 22.9 1.7 2.5 8.3 0.0 6.1 6 0 0 6 6 6 1 AAA domain PduV-EutP PF10662.9 RJW70886.1 - 0.00022 21.0 5.8 0.27 11.0 0.0 5.4 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 RJW70886.1 - 0.00022 20.7 0.0 1.9 7.9 0.0 4.6 4 0 0 4 4 4 1 Bacterial TniB protein ATPase_2 PF01637.18 RJW70886.1 - 0.00045 20.2 0.1 2.2 8.1 0.0 5.1 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 RJW70886.1 - 0.00095 19.2 0.1 10 6.2 0.0 5.0 5 0 0 5 5 5 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 RJW70886.1 - 0.0018 18.1 1.5 6.6 6.4 0.0 4.7 6 0 0 6 6 5 0 IstB-like ATP binding protein TIP49 PF06068.13 RJW70886.1 - 0.0048 16.1 1.0 0.033 13.4 0.0 2.8 4 0 0 4 4 4 1 TIP49 P-loop domain AAA_24 PF13479.6 RJW70886.1 - 0.009 15.7 0.4 7.8 6.2 0.0 4.4 6 0 0 6 6 5 0 AAA domain SRP54 PF00448.22 RJW70886.1 - 0.027 14.1 1.5 1.9 8.1 0.0 4.0 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 RJW70886.1 - 0.058 13.6 15.3 3.4 7.9 0.0 6.1 6 0 0 6 6 5 0 AAA domain DEAD PF00270.29 RJW70886.1 - 0.18 11.6 0.0 37 4.0 0.0 3.8 4 0 0 4 4 3 0 DEAD/DEAH box helicase AAA_11 PF13086.6 RJW70886.1 - 0.21 11.4 7.3 27 4.4 0.0 5.4 6 0 0 6 6 4 0 AAA domain ATP_bind_1 PF03029.17 RJW70886.1 - 0.3 10.9 2.3 18 5.0 0.0 3.8 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein dNK PF01712.19 RJW70886.1 - 0.41 10.5 1.2 72 3.1 0.0 3.7 4 0 0 4 4 4 0 Deoxynucleoside kinase NTPase_1 PF03266.15 RJW70886.1 - 4.9 7.0 7.1 94 2.9 0.0 4.8 6 0 0 6 6 6 0 NTPase RVT_1 PF00078.27 RJW70887.1 - 0.0001 21.9 0.0 0.0003 20.4 0.0 1.6 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) OCIA PF07051.11 RJW70888.1 - 0.1 12.6 0.1 0.52 10.4 0.0 2.2 3 0 0 3 3 3 0 Ovarian carcinoma immunoreactive antigen (OCIA) AAA_25 PF13481.6 RJW70889.1 - 9.8e-19 67.7 0.0 1.7e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 RJW70889.1 - 1.3e-12 47.7 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 RJW70889.1 - 2.5e-06 27.8 0.0 5.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 RJW70889.1 - 0.00013 21.4 0.0 0.00037 19.9 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_16 PF13191.6 RJW70889.1 - 0.00071 20.0 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 RJW70889.1 - 0.0025 17.6 0.1 0.031 14.0 0.0 2.5 2 1 1 3 3 3 1 IstB-like ATP binding protein NACHT PF05729.12 RJW70889.1 - 0.0083 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain T2SSE PF00437.20 RJW70889.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 RJW70889.1 - 0.027 14.2 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArsA_ATPase PF02374.15 RJW70889.1 - 0.037 13.2 0.1 0.099 11.8 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase RsgA_GTPase PF03193.16 RJW70889.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase CbiA PF01656.23 RJW70889.1 - 0.071 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 RJW70889.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 RJW70889.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain HD PF01966.22 RJW70890.1 - 7.5e-09 35.9 0.0 1.9e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 RJW70890.1 - 0.047 13.4 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Histone PF00125.24 RJW70891.1 - 6.2e-23 81.6 1.4 7.8e-23 81.3 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RJW70891.1 - 3.2e-06 27.3 0.0 8.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RJW70891.1 - 0.00098 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RJW70891.1 - 0.0026 17.8 0.5 0.003 17.6 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein CNDH2_C PF16858.5 RJW70891.1 - 0.0031 17.5 0.4 0.0033 17.4 0.4 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 RJW70892.1 - 2.6 6.2 7.2 2.8 6.1 7.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RJW70892.1 - 4.7 5.3 12.3 4.6 5.3 12.3 1.0 1 0 0 1 1 1 0 Nop14-like family BSD PF03909.17 RJW70894.1 - 1.4e-12 47.4 0.3 3.1e-12 46.3 0.3 1.5 1 0 0 1 1 1 1 BSD domain IPK PF03770.16 RJW70895.1 - 2.4e-37 128.7 0.0 2.9e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase MyTH4 PF00784.17 RJW70896.1 - 0.1 13.1 0.1 0.48 10.9 0.0 2.0 2 0 0 2 2 2 0 MyTH4 domain K_channel_TID PF07941.11 RJW70897.1 - 0.044 14.3 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain TPR_2 PF07719.17 RJW70898.1 - 2.2e-16 58.6 6.2 0.15 12.3 0.0 8.0 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 RJW70898.1 - 2.5e-16 58.4 1.1 0.0033 17.5 0.0 7.5 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 RJW70898.1 - 6.7e-15 54.2 5.0 0.016 15.0 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 RJW70898.1 - 2.6e-11 43.3 3.6 2 9.5 0.0 7.5 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 RJW70898.1 - 2.8e-07 30.5 1.6 1.7 9.2 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW70898.1 - 9.7e-07 29.0 12.7 0.094 13.0 0.1 6.2 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW70898.1 - 1.6e-06 28.7 0.3 0.21 12.3 0.0 5.2 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW70898.1 - 1e-05 26.0 0.0 13 6.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 RJW70898.1 - 3.6e-05 23.8 1.3 0.42 10.8 0.0 4.4 2 2 3 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW70898.1 - 4.7e-05 23.5 0.3 0.19 12.0 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RJW70898.1 - 9.7e-05 22.0 0.8 0.0061 16.2 0.0 4.0 5 0 0 5 5 5 1 TPR repeat Coatomer_E PF04733.14 RJW70898.1 - 0.00022 20.8 0.1 0.086 12.2 0.0 2.3 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_7 PF13176.6 RJW70898.1 - 0.0017 18.2 6.2 1.3 9.2 0.0 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 RJW70898.1 - 0.076 12.9 1.9 5.4 7.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 RJW70898.1 - 8.7 6.8 15.0 20 5.6 0.2 4.4 5 0 0 5 5 5 0 Bacterial transcriptional activator domain DUF746 PF05344.11 RJW70899.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Histone_H2A_C PF16211.5 RJW70901.1 - 3.1e-20 71.6 1.9 5e-20 71.0 1.9 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 RJW70901.1 - 3.2e-15 56.7 0.0 4.7e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RJW70901.1 - 2.5e-05 24.5 0.0 3.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Phosphodiest PF01663.22 RJW70903.1 - 3.3e-60 204.6 0.6 3.9e-60 204.3 0.6 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SH3_1 PF00018.28 RJW70904.1 - 5.4e-17 61.1 1.8 2.2e-11 43.2 0.0 4.6 5 0 0 5 5 5 3 SH3 domain SH3_2 PF07653.17 RJW70904.1 - 3e-13 49.2 0.0 3.5e-05 23.4 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.6 RJW70904.1 - 1.6e-09 37.5 0.3 3.6e-07 29.9 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain GluR_Homer-bdg PF10606.9 RJW70904.1 - 0.49 10.6 5.1 40 4.5 3.9 3.2 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor Nop PF01798.18 RJW70906.1 - 8.2e-80 267.6 0.2 8.2e-80 267.6 0.2 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 RJW70906.1 - 4.6e-18 65.4 0.7 1e-17 64.2 0.7 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Dynamin_N PF00350.23 RJW70908.1 - 2.5e-56 190.3 0.0 3e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RJW70908.1 - 4.8e-05 23.4 0.1 0.00011 22.3 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 RJW70908.1 - 0.043 14.0 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 RJW70908.1 - 0.047 13.9 0.2 3.2 8.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain Myb_Cef PF11831.8 RJW70912.1 - 5.3e-69 232.4 4.2 5.3e-69 232.4 4.2 3.1 3 1 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.6 RJW70912.1 - 1.6e-19 69.9 5.8 2.9e-11 43.4 2.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RJW70912.1 - 3.3e-18 65.6 5.4 2.5e-08 34.0 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Fz PF01392.22 RJW70913.1 - 3.8e-29 101.5 4.2 6e-29 100.9 4.2 1.3 1 0 0 1 1 1 1 Fz domain Mid1 PF12929.7 RJW70913.1 - 0.2 10.8 5.6 0.25 10.5 2.7 2.0 1 1 1 2 2 2 0 Stretch-activated Ca2+-permeable channel component 7tm_1 PF00001.21 RJW70915.1 - 4.8e-15 55.6 2.4 7.4e-15 55.0 2.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW70915.1 - 1.2e-09 37.9 7.1 2.9e-09 36.7 7.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RJW70915.1 - 0.00042 20.0 12.6 0.0026 17.4 12.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RJW70915.1 - 0.0067 15.8 7.4 0.042 13.2 0.2 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx F5_F8_type_C PF00754.25 RJW70916.1 - 1.1e-21 77.3 0.0 5.2e-18 65.4 0.0 2.7 2 0 0 2 2 2 2 F5/8 type C domain Plus-3 PF03126.18 RJW70918.1 - 5.1e-30 104.2 0.0 1.5e-29 102.7 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain RVT_1 PF00078.27 RJW70919.1 - 0.00041 19.9 0.0 0.00069 19.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-primase PF09329.11 RJW70922.1 - 1.5e-11 43.9 0.8 2.9e-11 43.0 0.8 1.5 1 0 0 1 1 1 1 Primase zinc finger EF-hand_1 PF00036.32 RJW70924.1 - 6.7e-17 59.7 0.4 0.011 15.2 0.0 5.6 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 RJW70924.1 - 6.8e-15 53.7 0.9 0.022 14.7 0.0 5.6 6 0 0 6 6 6 4 EF-hand domain EF-hand_7 PF13499.6 RJW70924.1 - 2.2e-12 47.3 8.2 0.00053 20.4 0.4 4.1 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 RJW70924.1 - 2.6e-08 33.6 1.2 0.15 11.9 0.0 5.6 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW70924.1 - 5.6e-08 31.9 8.6 0.092 12.3 0.0 5.4 6 0 0 6 6 6 3 EF hand SPARC_Ca_bdg PF10591.9 RJW70924.1 - 0.008 16.5 9.1 2.3 8.6 0.6 4.0 2 2 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW70924.1 - 0.009 16.0 1.5 0.15 12.1 0.0 3.0 3 1 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand BSP_II PF05432.11 RJW70924.1 - 0.07 12.8 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Dockerin_1 PF00404.18 RJW70924.1 - 0.098 12.9 0.0 31 4.8 0.0 3.2 3 0 0 3 3 3 0 Dockerin type I domain Antimicrobial_3 PF08025.11 RJW70924.1 - 1.2 9.1 3.4 2.9 7.9 0.0 3.1 3 1 0 3 3 3 0 Spider antimicrobial peptide VWA_2 PF13519.6 RJW70925.1 - 0.00047 20.8 0.2 0.00095 19.8 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RJW70925.1 - 0.00067 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 RJW70925.1 - 0.0053 16.2 1.9 0.023 14.1 2.0 1.9 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.6 RJW70925.1 - 0.039 13.9 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain T-box PF00907.22 RJW70926.1 - 1.4e-45 155.9 0.1 2.3e-45 155.1 0.1 1.4 1 0 0 1 1 1 1 T-box PRIMA1 PF16101.5 RJW70926.1 - 0.059 13.4 7.5 0.13 12.3 7.5 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 RJW70926.1 - 0.41 10.7 2.8 0.95 9.5 2.8 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator RVT_1 PF00078.27 RJW70927.1 - 3.7e-47 160.7 0.6 2.5e-46 158.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp PF00026.23 RJW70930.1 - 2.3e-05 24.0 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease MGAT2 PF05060.14 RJW70932.1 - 2.8e-34 118.7 0.0 3.7e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) CP_ATPgrasp_2 PF14403.6 RJW70934.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Lactamase_B_6 PF16661.5 RJW70935.1 - 2.1e-09 37.1 0.0 3.8e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 RJW70935.1 - 0.0006 19.1 0.0 0.0047 16.2 0.0 1.9 2 0 0 2 2 2 1 Putative beta-lactamase-like family Acyltransf_C PF16076.5 RJW70935.1 - 0.011 15.8 0.1 0.018 15.1 0.1 1.3 1 0 0 1 1 1 0 Acyltransferase C-terminus ExoD PF06055.12 RJW70936.1 - 0.044 13.2 0.2 0.088 12.2 0.2 1.4 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD tRNA-synt_1e PF01406.19 RJW70937.1 - 1.1e-72 244.9 0.0 1.7e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 RJW70937.1 - 0.00038 19.3 0.1 0.00058 18.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) RNase_P_pop3 PF08228.11 RJW70937.1 - 0.0034 17.4 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 RNase P subunit Pop3 tRNA-synt_1 PF00133.22 RJW70937.1 - 0.01 14.1 0.0 0.015 13.6 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Bromodomain PF00439.25 RJW70938.1 - 2.5e-20 72.3 0.0 4.9e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 RJW70938.1 - 7.6e-06 26.2 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RJW70938.1 - 0.0074 16.2 0.2 0.015 15.2 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RJW70938.1 - 0.016 15.6 0.2 0.03 14.8 0.2 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UPF0054 PF02130.17 RJW70938.1 - 0.056 13.3 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 tRNA-synt_1e PF01406.19 RJW70939.1 - 2.1e-42 145.5 0.1 3e-42 145.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain RRM_1 PF00076.22 RJW70941.1 - 4.3e-13 48.9 0.0 7.4e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RJW70941.1 - 0.049 13.6 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 RJW70941.1 - 0.071 13.0 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif RabGAP-TBC PF00566.18 RJW70942.1 - 1.2e-52 178.6 0.0 2.2e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Orthopox_35kD PF02250.15 RJW70942.1 - 0.034 13.8 0.1 0.065 12.9 0.1 1.4 1 0 0 1 1 1 0 35kD major secreted virus protein EF-hand_1 PF00036.32 RJW70943.1 - 3.5e-36 120.1 11.9 3.5e-09 35.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW70943.1 - 9.3e-32 109.3 2.9 1.1e-14 54.6 1.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RJW70943.1 - 5.8e-28 96.5 10.2 1.7e-12 47.0 0.1 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 RJW70943.1 - 5.9e-25 85.0 7.9 5.9e-09 35.1 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RJW70943.1 - 9.1e-23 78.7 9.5 3.1e-06 26.4 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RJW70943.1 - 1.4e-12 47.8 0.2 1.6e-08 34.7 0.0 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_4 PF12763.7 RJW70943.1 - 9.3e-07 28.8 0.4 0.05 13.5 0.1 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RJW70943.1 - 1e-05 25.8 0.0 0.1 12.9 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 RJW70943.1 - 0.00056 19.9 0.0 0.19 11.8 0.0 2.8 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 RJW70943.1 - 0.00074 19.6 0.2 0.0053 16.8 0.0 2.5 3 0 0 3 3 3 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 RJW70943.1 - 0.0013 19.6 0.0 0.14 13.1 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain DUF4497 PF14924.6 RJW70943.1 - 0.014 15.8 0.0 9.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Dockerin_1 PF00404.18 RJW70943.1 - 0.026 14.7 4.7 0.55 10.5 0.5 2.8 1 1 2 3 3 3 0 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 RJW70943.1 - 0.039 14.3 0.2 6.8 7.0 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF1103 PF06513.11 RJW70943.1 - 0.057 13.0 2.2 0.081 12.5 2.2 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Caleosin PF05042.13 RJW70943.1 - 0.063 13.2 0.1 2.1 8.2 0.0 2.7 1 1 2 3 3 3 0 Caleosin related protein DUF3349 PF11829.8 RJW70943.1 - 0.11 13.3 0.3 14 6.6 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Ras PF00071.22 RJW70946.1 - 9.1e-61 204.2 0.9 1.1e-60 203.9 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW70946.1 - 1.2e-33 115.8 1.1 1.8e-33 115.3 1.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW70946.1 - 3.9e-14 52.5 0.3 4.9e-14 52.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 RJW70946.1 - 1.5e-05 24.6 0.0 0.053 13.0 0.0 2.6 3 0 0 3 3 3 2 Ferrous iron transport protein B SRPRB PF09439.10 RJW70946.1 - 4.4e-05 23.0 0.1 0.00013 21.5 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RJW70946.1 - 0.00011 22.2 0.1 0.00023 21.2 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RJW70946.1 - 0.00018 21.0 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RJW70946.1 - 0.001 18.7 0.1 0.0033 17.0 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RJW70946.1 - 0.0037 17.2 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 RJW70946.1 - 0.021 14.0 0.2 6.1 5.9 0.0 2.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 RJW70946.1 - 0.071 12.8 0.2 0.18 11.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RJW70946.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain GST_C_3 PF14497.6 RJW70947.1 - 4.5e-15 55.6 0.1 6.8e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RJW70947.1 - 5.8e-11 42.6 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RJW70947.1 - 1.9e-10 40.8 0.1 3.3e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Innexin PF00876.18 RJW70949.1 - 1.9e-55 188.6 0.2 2.2e-55 188.4 0.2 1.0 1 0 0 1 1 1 1 Innexin Ion_trans PF00520.31 RJW70950.1 - 2.1e-17 63.2 8.4 2.1e-17 63.2 8.4 1.6 2 0 0 2 2 2 1 Ion transport protein CAP_N PF01213.19 RJW70951.1 - 0.048 13.2 0.7 0.049 13.1 0.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TAP_C PF03943.13 RJW70953.1 - 1.3e-12 47.1 0.1 2.3e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 RJW70953.1 - 0.089 12.6 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 UBA-like domain Ank_2 PF12796.7 RJW70955.1 - 2e-19 70.0 0.2 1.1e-06 29.1 0.1 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Notch PF00066.17 RJW70955.1 - 5.1e-16 58.8 25.5 1.1e-09 38.6 10.7 5.7 5 0 0 5 5 5 2 LNR domain EGF PF00008.27 RJW70955.1 - 9.7e-15 54.6 81.0 3.8e-07 30.3 8.4 9.3 8 2 0 8 8 8 5 EGF-like domain Ank_4 PF13637.6 RJW70955.1 - 2e-07 31.4 0.8 0.021 15.4 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RJW70955.1 - 4.9e-06 26.7 0.1 0.0096 16.3 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 RJW70955.1 - 1e-05 25.5 4.1 0.067 13.8 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 RJW70955.1 - 2.2e-05 24.6 4.2 0.14 12.5 0.1 5.2 3 1 3 6 6 6 2 Ankyrin repeats (many copies) hEGF PF12661.7 RJW70955.1 - 0.00018 22.0 18.0 0.00046 20.7 6.2 10.2 10 1 0 10 10 10 4 Human growth factor-like EGF EGF_2 PF07974.13 RJW70955.1 - 0.0048 17.2 10.9 0.0048 17.2 10.9 8.7 9 0 0 9 9 9 3 EGF-like domain DSL PF01414.19 RJW70955.1 - 0.0081 16.4 8.2 0.0081 16.4 8.2 6.0 3 2 1 5 5 5 1 Delta serrate ligand zf-C2H2 PF00096.26 RJW70956.1 - 4.2e-06 26.9 32.0 0.017 15.5 0.8 8.4 8 0 0 8 8 8 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW70956.1 - 0.00057 20.5 41.0 0.1 13.5 1.1 8.6 9 0 0 9 9 9 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW70956.1 - 0.0051 17.1 6.7 3.9 7.9 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Fer2 PF00111.27 RJW70956.1 - 0.031 14.2 8.8 0.3 11.1 0.7 4.0 4 0 0 4 4 4 0 2Fe-2S iron-sulfur cluster binding domain Rad50_zn_hook PF04423.14 RJW70956.1 - 0.24 11.3 1.7 1.9 8.4 0.0 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.7 RJW70956.1 - 0.57 10.5 23.5 1.1 9.6 0.2 5.6 2 2 5 7 7 7 0 C2H2 type zinc-finger (2 copies) HIPIP PF01355.17 RJW70956.1 - 1.3 9.4 5.6 0.64 10.4 0.4 2.9 2 0 0 2 2 2 0 High potential iron-sulfur protein DUF1330 PF07045.11 RJW70957.1 - 6e-08 32.9 0.0 0.0024 18.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) Formyl_trans_N PF00551.19 RJW70958.1 - 3e-19 69.5 0.0 4.4e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 RJW70958.1 - 0.0094 16.2 0.0 0.03 14.6 0.0 1.8 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Innexin PF00876.18 RJW70959.1 - 7.1e-15 55.2 0.0 7.5e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Innexin SecG PF03840.14 RJW70959.1 - 0.022 14.8 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 Preprotein translocase SecG subunit cNMP_binding PF00027.29 RJW70960.1 - 5.1e-18 64.9 0.0 9.5e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain GIT_CC PF16559.5 RJW70960.1 - 0.058 13.3 1.1 0.12 12.3 1.1 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor BRAP2 PF07576.12 RJW70960.1 - 0.16 12.2 0.1 0.31 11.3 0.1 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 Cullin_binding PF03556.15 RJW70962.1 - 1.7e-33 115.6 0.5 1.7e-33 115.6 0.5 1.6 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 RJW70962.1 - 1.2e-11 44.3 0.0 3.1e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 RJW70962.1 - 0.0019 17.8 0.4 0.0043 16.7 0.4 1.5 1 0 0 1 1 1 1 TAP C-terminal domain FA_hydroxylase PF04116.13 RJW70965.1 - 1.5 9.2 6.6 0.51 10.7 3.4 1.8 2 1 0 2 2 2 0 Fatty acid hydroxylase superfamily zf-C2H2 PF00096.26 RJW70966.1 - 1.3e-11 44.2 21.1 3.2e-05 24.2 2.0 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW70966.1 - 1.6e-09 37.7 12.9 2.1e-06 27.9 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW70966.1 - 8.8e-08 32.4 22.8 0.0021 18.7 1.4 4.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW70966.1 - 3.3e-06 27.0 12.5 0.00024 21.0 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW70966.1 - 0.029 14.7 6.2 8.7 6.8 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW70966.1 - 0.078 13.4 6.4 5 7.6 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type C1_4 PF07975.12 RJW70966.1 - 0.38 11.0 6.0 3.6 7.9 0.1 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain zf-MYST PF17772.1 RJW70966.1 - 0.45 10.2 5.7 0.5 10.0 0.7 3.0 1 1 1 2 2 2 0 MYST family zinc finger domain Zf_RING PF16744.5 RJW70966.1 - 3.7 7.7 8.5 22 5.2 0.2 3.7 1 1 2 3 3 3 0 KIAA1045 RING finger PQ-loop PF04193.14 RJW70968.1 - 1.3e-18 66.5 1.5 2.7e-18 65.5 1.5 1.6 1 0 0 1 1 1 1 PQ loop repeat LSM PF01423.22 RJW70968.1 - 3.7e-08 32.9 0.3 8.1e-08 31.9 0.3 1.6 1 0 0 1 1 1 1 LSM domain MtN3_slv PF03083.16 RJW70968.1 - 0.0022 18.0 0.1 0.0045 17.0 0.1 1.5 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange HisKA_7TM PF16927.5 RJW70968.1 - 0.024 14.7 0.3 0.032 14.3 0.3 1.2 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase SM-ATX PF14438.6 RJW70968.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain XPA_C PF05181.12 RJW70969.1 - 2.3e-22 78.7 0.8 2.5e-21 75.4 0.1 2.4 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 RJW70969.1 - 1.2e-12 47.6 8.9 1.2e-12 47.6 8.9 2.2 2 0 0 2 2 2 1 XPA protein N-terminal HisK_sensor PF18698.1 RJW70969.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase sensor domain Ion_trans_N PF08412.10 RJW70969.1 - 0.18 11.4 0.1 0.41 10.3 0.1 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal zf-TFIIB PF13453.6 RJW70969.1 - 0.8 9.1 6.0 3.8 6.9 2.3 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger FYVE PF01363.21 RJW70969.1 - 2.2 8.5 6.3 8 6.7 3.8 2.6 2 1 0 2 2 2 0 FYVE zinc finger Fer4_2 PF12797.7 RJW70969.1 - 8.8 6.7 7.2 7.8 6.8 0.3 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain DUF1248 PF06852.12 RJW70970.1 - 0.064 12.7 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) SH3_1 PF00018.28 RJW70971.1 - 1.8e-09 37.1 0.0 3.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RJW70971.1 - 5.4e-09 35.8 0.1 1.8e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 RJW70971.1 - 2.6e-07 30.2 0.0 5.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mis12 PF05859.12 RJW70971.1 - 0.12 12.4 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Mis12 protein PP-binding PF00550.25 RJW70972.1 - 6.1e-08 32.9 0.1 2.1e-07 31.2 0.1 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site UDPGP PF01704.18 RJW70973.1 - 6.4e-172 571.8 0.0 7.3e-172 571.6 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase AMP-binding PF00501.28 RJW70975.1 - 1.9e-28 99.3 0.0 1.1e-25 90.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 RJW70975.1 - 1.7e-05 25.1 0.9 2.7e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Cnl2_NKP2 PF09447.10 RJW70975.1 - 0.058 13.6 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Ras PF00071.22 RJW70976.1 - 4.4e-23 81.7 0.0 5.7e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW70976.1 - 1.3e-10 41.5 0.0 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RJW70976.1 - 6.1e-06 25.9 0.0 0.0014 18.2 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RJW70976.1 - 0.00097 19.2 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RJW70976.1 - 0.0018 18.2 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 RJW70976.1 - 0.002 17.6 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Terminase_GpA PF05876.12 RJW70976.1 - 0.14 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) PduV-EutP PF10662.9 RJW70976.1 - 0.2 11.4 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ECSIT PF06239.11 RJW70977.1 - 1.1e-61 207.8 0.1 2.3e-61 206.8 0.1 1.4 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway PITH PF06201.13 RJW70977.1 - 8.6e-24 84.5 0.0 1.9e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 PITH domain ECSIT_C PF14784.6 RJW70977.1 - 2e-06 28.2 1.0 0.63 10.4 0.0 4.6 4 0 0 4 4 4 2 C-terminal domain of the ECSIT protein XPG_N PF00752.17 RJW70977.1 - 8.6e-05 22.9 0.0 0.00019 21.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain GEMIN8 PF15348.6 RJW70977.1 - 0.00082 19.7 2.1 0.00082 19.7 2.1 2.2 2 0 0 2 2 2 1 Gemini of Cajal bodies-associated protein 8 XPG_I_2 PF12813.7 RJW70977.1 - 0.0043 16.6 0.5 0.012 15.1 0.3 1.8 2 0 0 2 2 2 1 XPG domain containing Ski_Sno PF02437.17 RJW70979.1 - 9.4e-37 125.1 0.1 9.4e-37 125.1 0.1 1.8 2 0 0 2 2 2 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 RJW70979.1 - 4.6e-29 100.5 3.6 4.6e-29 100.5 3.6 2.0 2 0 0 2 2 2 1 c-SKI Smad4 binding domain ERCC3_RAD25_C PF16203.5 RJW70980.1 - 7e-120 398.8 0.2 1.2e-119 398.0 0.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 RJW70980.1 - 1.7e-33 115.5 0.0 3.7e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW70980.1 - 9.8e-16 58.2 0.0 1.7e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RJW70980.1 - 5.1e-10 39.7 0.0 1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 RJW70980.1 - 0.0011 17.8 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain RNR_N PF08343.10 RJW70980.1 - 0.039 14.0 0.4 0.16 12.0 0.2 2.0 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal Rad21_Rec8_N PF04825.13 RJW70981.1 - 5.1e-40 136.1 0.0 1.1e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 RJW70981.1 - 2.3e-15 55.6 0.1 1.1e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 RJW70981.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Segregation and condensation protein ScpA PDCD2_C PF04194.13 RJW70982.1 - 1.1e-32 113.5 4.2 1.2e-31 110.2 0.5 2.6 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain zf-Di19 PF05605.12 RJW70982.1 - 0.12 12.6 3.6 14 6.1 0.0 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RRN7 PF11781.8 RJW70982.1 - 4.1 7.2 8.6 16 5.3 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 SNF2_N PF00176.23 RJW70983.1 - 4.8e-53 180.1 0.0 1.9e-37 128.8 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW70983.1 - 1.2e-14 54.6 0.0 2.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW70983.1 - 0.017 15.2 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Elicitin PF00964.17 RJW70983.1 - 0.44 10.7 6.6 0.045 13.9 0.5 2.3 2 0 0 2 2 2 0 Elicitin DDE_Tnp_IS1595 PF12762.7 RJW70985.1 - 9e-11 42.0 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain SNAD3 PF18749.1 RJW70985.1 - 0.0022 17.2 0.1 0.0032 16.7 0.1 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 3 DDE_Tnp_IS1 PF03400.13 RJW70985.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 IS1 transposase Pet100 PF09803.9 RJW70986.1 - 9.5e-05 22.8 0.0 0.00013 22.4 0.0 1.2 1 0 0 1 1 1 1 Pet100 DDE_Tnp_IS1595 PF12762.7 RJW70987.1 - 5.9e-11 42.6 0.3 2.5e-10 40.6 0.1 2.0 2 1 0 2 2 2 1 ISXO2-like transposase domain CBM46 PF18448.1 RJW70987.1 - 0.023 15.0 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain DDE_Tnp_IS1 PF03400.13 RJW70987.1 - 0.073 13.4 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 IS1 transposase RVT_1 PF00078.27 RJW70988.1 - 7.7e-45 153.1 0.0 1.3e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_5 PF13893.6 RJW70988.1 - 8.3e-44 148.2 0.0 7.7e-35 119.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RJW70988.1 - 6.8e-25 86.7 0.0 9.2e-07 28.6 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RJW70988.1 - 3.3e-14 52.9 0.2 1.6e-13 50.7 0.1 2.2 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 RJW70988.1 - 4.5e-08 32.8 0.0 0.18 11.7 0.0 3.6 3 0 0 3 3 3 3 Occluded RNA-recognition motif RL PF17797.1 RJW70988.1 - 1.9e-05 24.5 0.0 0.65 10.0 0.0 3.7 3 0 0 3 3 3 2 RL domain Exo_endo_phos PF03372.23 RJW70988.1 - 0.00013 21.6 0.8 0.00042 19.9 0.3 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Limkain-b1 PF11608.8 RJW70988.1 - 0.0022 18.0 0.0 3 8.0 0.0 3.1 3 0 0 3 3 3 2 Limkain b1 Ras PF00071.22 RJW70992.1 - 2.3e-63 212.6 0.2 3.6e-63 212.0 0.2 1.3 1 0 0 1 1 1 1 Ras family RVT_1 PF00078.27 RJW70992.1 - 1.6e-46 158.6 0.0 2.6e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Roc PF08477.13 RJW70992.1 - 4.2e-33 114.1 0.2 6.8e-33 113.4 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW70992.1 - 9.1e-15 54.5 0.1 1.5e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RJW70992.1 - 0.00023 21.1 0.2 0.69 9.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 RJW70992.1 - 0.00041 19.8 0.2 0.0007 19.0 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RJW70992.1 - 0.00072 19.1 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 RJW70992.1 - 0.0032 16.9 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RJW70992.1 - 0.0059 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.14 RJW70992.1 - 0.011 15.7 0.0 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RJW70992.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain UPF0565 PF10561.9 RJW70993.1 - 1.2e-41 142.8 0.0 6.4e-22 78.1 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 RVT_1 PF00078.27 RJW70994.1 - 1.3e-44 152.4 0.0 2.5e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LEDGF PF11467.8 RJW70994.1 - 5.3e-18 64.8 2.4 9.6e-18 63.9 2.4 1.5 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) Ribosomal_S19e PF01090.19 RJW70995.1 - 0.054 13.2 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S19e RRM_5 PF13893.6 RJW70996.1 - 7.5e-49 164.5 0.0 1.1e-38 131.6 0.0 3.5 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.26 RJW70996.1 - 3.7e-33 114.6 0.0 5.3e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit RRM_1 PF00076.22 RJW70996.1 - 5.1e-17 61.5 0.0 6e-07 29.2 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RJW70996.1 - 1.4e-12 47.6 0.0 3.7e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 RJW70996.1 - 3.2e-05 23.7 0.0 0.098 12.5 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 RJW70996.1 - 0.0052 16.8 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 RJW70996.1 - 0.063 13.4 0.2 0.48 10.5 0.0 2.4 3 0 0 3 3 3 0 Limkain b1 PDEase_I PF00233.19 RJW70998.1 - 9.7e-50 169.5 1.5 1.7e-49 168.7 1.5 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF1652 PF07865.11 RJW70999.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) E1_DerP2_DerF2 PF02221.15 RJW71000.1 - 0.0013 19.2 0.0 0.0021 18.5 0.0 1.4 1 1 0 1 1 1 1 ML domain 7tm_1 PF00001.21 RJW71001.1 - 1.4e-14 54.0 18.3 9.7e-14 51.3 18.3 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW71001.1 - 2.7e-07 30.2 13.5 4e-05 23.1 0.4 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Mntp PF02659.15 RJW71001.1 - 0.016 14.9 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Putative manganese efflux pump 7TM_GPCR_Srx PF10328.9 RJW71001.1 - 1.3 8.6 15.4 0.023 14.3 7.0 2.3 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx zf-C2H2_4 PF13894.6 RJW71005.1 - 3.8e-13 49.1 41.4 0.0081 16.9 3.5 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW71005.1 - 1.2e-12 47.5 41.2 0.00087 19.6 3.7 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW71005.1 - 0.00012 22.3 35.3 0.028 14.8 1.9 6.5 6 1 0 6 6 6 2 Zinc-finger double domain zf-BED PF02892.15 RJW71005.1 - 0.0079 16.2 4.4 0.0079 16.2 4.4 4.1 3 1 1 4 4 4 1 BED zinc finger zf-C2H2_3rep PF18868.1 RJW71005.1 - 0.066 13.9 13.9 10 6.8 0.3 4.6 1 1 4 5 5 5 0 Zinc finger C2H2-type, 3 repeats ARS2 PF04959.13 RJW71005.1 - 0.086 13.2 2.4 1.4 9.2 1.6 2.5 2 0 0 2 2 2 0 Arsenite-resistance protein 2 PyrI_C PF02748.15 RJW71005.1 - 0.13 12.2 6.8 2.7 7.9 0.3 3.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_C2H2_ZHX PF18387.1 RJW71005.1 - 2 8.1 9.4 2.4 7.9 0.2 3.2 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 RJW71005.1 - 2.4 8.0 21.8 0.54 10.1 0.2 4.4 5 0 0 5 5 5 0 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 RJW71005.1 - 2.5 8.5 14.1 3.2 8.1 0.1 4.0 5 0 0 5 5 5 0 zinc-ribbon FYVE PF01363.21 RJW71005.1 - 4.9 7.4 28.7 1.2 9.3 12.2 2.9 1 1 1 2 2 2 0 FYVE zinc finger SEA PF01390.20 RJW71006.1 - 0.15 12.2 0.0 1.1 9.4 0.0 2.3 3 0 0 3 3 3 0 SEA domain zf-C2H2 PF00096.26 RJW71007.1 - 1.4e-11 44.2 51.5 0.0012 19.1 1.1 8.3 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW71007.1 - 1.2e-08 35.1 50.0 0.035 15.0 0.8 8.2 8 0 0 8 8 8 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW71007.1 - 3.7e-06 27.1 41.8 0.062 13.8 0.9 8.0 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_11 PF16622.5 RJW71007.1 - 7.8e-05 22.4 24.4 0.021 14.6 0.0 5.5 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RJW71007.1 - 0.014 15.4 38.9 0.45 10.6 0.5 7.2 7 0 0 7 7 7 0 C2H2-type zinc finger Trm112p PF03966.16 RJW71007.1 - 0.082 13.5 0.0 2.5 8.7 0.0 3.2 2 2 0 2 2 2 0 Trm112p-like protein zf-met PF12874.7 RJW71007.1 - 1.1 9.8 19.8 6 7.4 0.3 6.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type CxC3 PF18804.1 RJW71007.1 - 4.2 7.3 9.7 1.9 8.3 0.1 3.8 3 1 0 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases DUF4588 PF15251.6 RJW71009.1 - 0.11 12.2 3.1 0.26 11.0 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) Sdh_cyt PF01127.22 RJW71010.1 - 5.8e-21 74.8 1.7 7.5e-21 74.4 1.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NDK PF00334.19 RJW71011.1 - 2.7e-101 335.0 0.0 2.9e-34 118.0 0.0 3.2 3 0 0 3 3 3 3 Nucleoside diphosphate kinase Thioredoxin PF00085.20 RJW71011.1 - 2.6e-06 27.3 0.0 6.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Sigma70_r1_1 PF03979.14 RJW71011.1 - 0.36 10.9 0.0 0.36 10.9 0.0 3.9 3 1 1 4 4 4 0 Sigma-70 factor, region 1.1 Pkinase_Tyr PF07714.17 RJW71013.1 - 2.8e-30 105.5 0.0 8.8e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW71013.1 - 2.8e-18 66.2 0.0 2.7e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain zf-C2H2 PF00096.26 RJW71014.1 - 1.5e-09 37.7 20.8 1.6e-05 25.1 1.5 4.0 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW71014.1 - 2e-07 31.1 9.8 2e-05 24.8 0.4 4.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW71014.1 - 0.00015 22.3 15.8 0.024 15.4 1.6 4.0 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW71014.1 - 0.0011 18.9 1.5 0.0011 18.9 1.5 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger Nudix_N_2 PF14803.6 RJW71014.1 - 0.0031 17.4 1.5 0.18 11.8 0.1 2.4 2 0 0 2 2 2 1 Nudix N-terminal zf-C2H2_11 PF16622.5 RJW71014.1 - 0.0039 16.9 9.9 0.064 13.0 1.2 2.8 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RJW71014.1 - 0.0045 17.2 2.6 1.1 9.6 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 RJW71014.1 - 0.016 14.8 2.4 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 RJW71014.1 - 0.017 15.8 4.9 0.088 13.5 0.3 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats PhnA_Zn_Ribbon PF08274.12 RJW71014.1 - 0.028 14.4 1.0 5 7.2 0.2 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon XPA_N PF01286.18 RJW71014.1 - 0.039 14.0 0.1 0.039 14.0 0.1 2.7 3 0 0 3 3 3 0 XPA protein N-terminal TF_Zn_Ribbon PF08271.12 RJW71014.1 - 0.16 11.5 4.4 3.8 7.1 1.4 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-H2C2_5 PF13909.6 RJW71014.1 - 1.4 8.8 0.0 1.4 8.8 0.0 4.4 5 0 0 5 5 5 0 C2H2-type zinc-finger domain GATA PF00320.27 RJW71014.1 - 1.7 8.3 6.2 4.6 6.9 0.1 2.6 3 0 0 3 3 3 0 GATA zinc finger zf_C2H2_ZHX PF18387.1 RJW71014.1 - 7.7 6.3 12.3 0.7 9.6 2.2 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 RJW71015.1 - 0.00035 20.9 1.6 0.00035 20.9 1.6 4.6 4 0 0 4 4 4 1 Zinc-finger double domain RVT_1 PF00078.27 RJW71015.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_4 PF13894.6 RJW71015.1 - 0.07 14.0 1.0 0.07 14.0 1.0 6.6 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW71015.1 - 0.082 13.4 0.6 0.082 13.4 0.6 6.6 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW71015.1 - 0.12 12.6 12.1 0.38 11.1 0.7 3.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_11 PF11682.8 RJW71015.1 - 0.17 11.9 2.8 0.13 12.3 0.8 1.7 2 0 0 2 2 2 0 Probable zinc-ribbon zf-C2H2_3rep PF18868.1 RJW71015.1 - 2.4 8.9 9.2 5.7 7.6 6.7 2.7 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats TRP_2 PF08344.11 RJW71017.1 - 2.2e-27 95.1 1.6 4.3e-27 94.1 1.6 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 RJW71017.1 - 1.2e-10 41.0 9.4 1.2e-10 41.0 9.4 1.8 2 1 0 2 2 2 1 Ion transport protein Ank_2 PF12796.7 RJW71017.1 - 4.4e-09 36.8 0.7 1.5e-05 25.5 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW71017.1 - 8.8e-09 34.9 3.6 0.028 15.0 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RJW71017.1 - 3.4e-06 27.5 0.2 0.14 12.8 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW71017.1 - 3.3e-05 24.1 0.3 0.67 10.3 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RJW71017.1 - 9.7e-05 22.6 1.0 2.5 8.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Transpos_assoc PF13963.6 RJW71017.1 - 0.053 13.8 0.7 1.8 8.9 0.2 2.8 2 0 0 2 2 2 0 Transposase-associated domain GDA1_CD39 PF01150.17 RJW71018.1 - 5e-70 236.3 0.0 7.9e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Lectin_leg-like PF03388.13 RJW71019.1 - 0.12 11.7 0.1 0.45 9.8 0.0 1.8 1 1 1 2 2 2 0 Legume-like lectin family Ion_trans PF00520.31 RJW71020.1 - 1.9e-05 24.0 0.0 3.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ion transport protein DUF1664 PF07889.12 RJW71020.1 - 0.0052 16.8 3.4 0.012 15.6 3.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) AATF-Che1 PF13339.6 RJW71020.1 - 0.16 12.6 3.6 0.086 13.5 1.1 1.7 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor fn3 PF00041.21 RJW71022.1 - 2.6e-29 101.4 14.6 2.5e-07 30.9 0.7 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW71022.1 - 4.4e-05 24.0 6.9 0.74 10.4 0.2 5.0 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Il13Ra_Ig PF18001.1 RJW71022.1 - 0.011 15.8 1.3 1.6 8.9 0.1 3.0 2 0 0 2 2 2 0 Interleukin-13 receptor subunit alpha Ig-like domain fn3_2 PF16893.5 RJW71022.1 - 0.026 14.7 0.1 0.23 11.6 0.0 2.7 2 0 0 2 2 2 0 Fibronectin type III domain SusE PF14292.6 RJW71022.1 - 0.028 14.6 10.1 2.9 8.2 1.5 4.2 3 1 0 3 3 3 0 SusE outer membrane protein PhoD_N PF16655.5 RJW71022.1 - 0.13 12.8 0.5 2.9 8.5 0.1 3.0 3 0 0 3 3 3 0 PhoD-like phosphatase, N-terminal domain DUF2369 PF10179.9 RJW71022.1 - 0.15 12.4 2.0 3 8.3 0.1 3.6 4 1 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) DUF1282 PF06930.12 RJW71023.1 - 0.19 11.5 4.6 0.32 10.8 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Asp PF00026.23 RJW71024.1 - 1.1e-15 57.8 0.0 1.3e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease ATP-synt_DE_N PF02823.16 RJW71028.1 - 2.6e-10 40.0 0.0 3.9e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Rad17 PF03215.15 RJW71030.1 - 1.2e-15 57.9 0.0 2.8e-15 56.7 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 RJW71030.1 - 2.4e-05 24.8 0.0 4.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 RJW71030.1 - 0.0025 18.3 0.0 0.028 14.9 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 RJW71030.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RJW71030.1 - 0.0095 16.0 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RJW71030.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 RJW71030.1 - 0.024 15.1 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 RJW71030.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 RJW71030.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain Asp PF00026.23 RJW71031.1 - 6.7e-19 68.4 0.0 8.6e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW71031.1 - 5.5e-12 46.3 0.2 1.1e-08 35.5 0.1 2.1 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal DUF676 PF05057.14 RJW71032.1 - 1.4e-32 113.0 0.0 1.7e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 RJW71032.1 - 0.0016 18.2 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 RJW71032.1 - 0.0058 16.5 0.0 0.0064 16.4 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 RJW71032.1 - 0.027 13.6 0.1 0.038 13.2 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 RJW71032.1 - 0.059 14.0 0.0 0.072 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PRP1_N PF06424.12 RJW71033.1 - 2.9e-20 73.2 3.2 3.7e-20 72.8 3.2 1.1 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal DUF3987 PF13148.6 RJW71033.1 - 0.31 10.0 1.6 0.36 9.8 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) zf_CCCH_4 PF18345.1 RJW71036.1 - 1.1e-17 63.5 28.4 3.4e-08 33.3 3.4 3.5 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 RJW71036.1 - 1.3e-15 56.8 26.2 5.2e-06 26.2 3.9 3.4 2 1 1 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RJW71036.1 - 4.8e-10 39.0 23.8 0.00041 20.1 4.8 3.5 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 RJW71036.1 - 4.6e-06 27.3 19.6 0.0034 18.1 1.5 3.7 2 1 2 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 RJW71036.1 - 3.1e-05 24.1 17.4 0.0015 18.7 5.0 3.2 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 RJW71036.1 - 0.0012 19.2 25.9 0.0041 17.6 4.0 4.4 3 1 0 3 3 3 2 RNA-binding, Nab2-type zinc finger UCH PF00443.29 RJW71039.1 - 3.8e-41 141.3 0.0 5e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW71039.1 - 3.6e-08 33.4 0.0 0.0022 17.7 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.29 RJW71040.1 - 4.5e-38 130.7 0.0 7e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW71040.1 - 2.3e-10 40.1 0.1 5e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 RJW71040.1 - 6.7e-07 29.2 0.0 2.4e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 RJW71040.1 - 1.3e-05 25.1 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RJW71040.1 - 0.00018 21.5 0.2 0.00072 19.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RJW71040.1 - 0.00066 20.0 2.0 0.044 14.0 0.1 2.7 1 1 2 3 3 3 1 AAA domain TIP49 PF06068.13 RJW71040.1 - 0.0022 17.3 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 RJW71040.1 - 0.0032 17.9 1.7 0.11 12.9 0.1 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 RJW71040.1 - 0.006 16.7 0.0 0.016 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 RJW71040.1 - 0.027 13.8 0.1 0.097 12.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 RJW71040.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RJW71040.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 RJW71040.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 RJW71040.1 - 0.11 12.2 0.1 1.1 9.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RT_RNaseH_2 PF17919.1 RJW71042.1 - 1.1e-21 76.8 0.0 2.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW71042.1 - 3.4e-19 69.1 0.0 1.2e-18 67.3 0.0 1.9 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase LSM PF01423.22 RJW71042.1 - 3.4e-09 36.2 0.0 5.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain PKcGMP_CC PF16808.5 RJW71043.1 - 0.003 17.4 6.0 0.003 17.4 6.0 3.6 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Apolipoprotein PF01442.18 RJW71043.1 - 0.0059 16.5 38.4 0.0059 16.5 38.4 2.9 2 2 0 2 2 2 1 Apolipoprotein A1/A4/E domain Filament PF00038.21 RJW71043.1 - 0.015 14.9 63.7 0.092 12.3 16.9 3.7 1 1 2 3 3 3 0 Intermediate filament protein Fez1 PF06818.15 RJW71043.1 - 5.3 7.4 65.3 23 5.4 29.8 3.3 1 1 2 3 3 3 0 Fez1 T7SS_ESX_EspC PF10824.8 RJW71043.1 - 7 7.2 11.7 0.5 10.9 1.0 3.5 2 1 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm CwfJ_C_1 PF04677.15 RJW71044.1 - 1.7e-32 111.9 0.0 3.4e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 RJW71044.1 - 2.4e-10 41.2 0.0 6.5e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-C3HC4_2 PF13923.6 RJW71045.1 - 2.3e-14 52.9 9.0 4.6e-14 52.0 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW71045.1 - 9.7e-10 38.2 9.1 1.8e-09 37.3 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW71045.1 - 9.1e-09 35.5 7.8 1.9e-08 34.5 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RJW71045.1 - 4.4e-07 29.6 7.2 6.9e-07 29.0 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 RJW71045.1 - 3.3e-06 27.7 0.3 6.7e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_UBOX PF13445.6 RJW71045.1 - 2.1e-05 24.4 7.5 5.2e-05 23.2 7.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RJW71045.1 - 4.3e-05 23.4 8.0 7.6e-05 22.6 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 RJW71045.1 - 0.00015 21.5 4.3 0.0003 20.5 4.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 RJW71045.1 - 0.0002 21.4 7.3 0.00046 20.3 7.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 RJW71045.1 - 0.00046 20.0 3.6 0.00092 19.0 3.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 RJW71045.1 - 0.0014 18.4 6.6 0.0033 17.2 6.6 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 RJW71045.1 - 0.0037 17.5 7.7 0.021 15.1 7.8 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RJW71045.1 - 0.029 14.2 7.8 0.95 9.4 8.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C4_Topoisom PF01396.19 RJW71045.1 - 0.083 12.7 0.3 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger Pas_Saposin PF09016.10 RJW71045.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Pas factor saposin fold zf-ANAPC11 PF12861.7 RJW71045.1 - 0.16 12.0 1.6 0.33 11.0 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 RJW71045.1 - 0.18 11.9 2.4 0.45 10.7 2.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_5 PF17121.5 RJW71045.1 - 0.19 11.7 7.4 0.71 9.8 7.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF410 PF04190.13 RJW71046.1 - 1.3e-60 205.4 0.1 1.6e-60 205.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) HSP70 PF00012.20 RJW71047.1 - 1.3e-145 485.9 0.5 1.5e-145 485.8 0.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RJW71047.1 - 4.7e-19 68.4 0.4 2.9e-18 65.8 0.2 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 RJW71047.1 - 0.01 15.1 0.2 0.02 14.2 0.2 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 RJW71047.1 - 0.018 14.3 0.8 0.083 12.1 0.1 2.0 1 1 1 2 2 2 0 StbA protein LRR_6 PF13516.6 RJW71048.1 - 0.016 15.2 0.9 8.8 6.7 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 RJW71048.1 - 0.084 12.6 0.1 0.084 12.6 0.1 3.1 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 RJW71048.1 - 1.8 9.1 6.4 31 5.2 0.3 3.2 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW71048.1 - 2 9.3 7.9 38 5.4 0.5 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat TPT PF03151.16 RJW71049.1 - 1.9e-15 57.0 19.6 2.7e-15 56.5 19.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RJW71049.1 - 5.5e-07 29.8 31.0 0.00028 21.1 15.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 RJW71049.1 - 0.31 10.2 21.5 0.058 12.6 2.5 2.4 1 1 0 2 2 2 0 Purine nucleobase transmembrane transport Ndr PF03096.14 RJW71051.1 - 2.1e-48 164.4 0.0 1.2e-38 132.4 0.0 2.3 1 1 1 2 2 2 2 Ndr family Abhydrolase_1 PF00561.20 RJW71051.1 - 0.00028 20.6 0.0 0.017 14.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold SUFU_C PF12470.8 RJW71052.1 - 7.7e-41 140.4 0.0 1.1e-37 130.1 0.0 2.3 2 0 0 2 2 2 2 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.13 RJW71052.1 - 1.4e-40 139.1 0.0 6.2e-23 81.7 0.0 2.3 2 0 0 2 2 2 2 Suppressor of fused protein (SUFU) ATP_bind_1 PF03029.17 RJW71053.1 - 9.8e-78 261.3 0.0 1.5e-77 260.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein FtsJ PF01728.19 RJW71053.1 - 3.6e-40 138.0 0.0 5.9e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase YdjM PF04307.14 RJW71053.1 - 3.4e-07 29.7 4.3 7e-07 28.7 4.3 1.5 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase NB-ARC PF00931.22 RJW71053.1 - 0.048 12.8 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 RJW71053.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 RJW71053.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RJW71053.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_16 PF13191.6 RJW71053.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 RJW71053.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Asp PF00026.23 RJW71054.1 - 1.2e-30 107.0 0.0 1.5e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 RJW71054.1 - 0.0033 18.0 0.0 2 9.1 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 RJW71054.1 - 0.011 16.3 0.0 0.8 10.3 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 RJW71054.1 - 0.12 12.1 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Enolase_C PF00113.22 RJW71055.1 - 5.1e-11 42.3 0.0 5.6e-10 38.9 0.0 2.2 2 1 0 2 2 2 1 Enolase, C-terminal TIM barrel domain DUF4158 PF13700.6 RJW71056.1 - 0.017 15.0 0.3 0.039 13.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) SYF2 PF08231.12 RJW71057.1 - 1.3e-43 149.1 12.9 1.3e-43 149.1 12.9 1.5 2 0 0 2 2 2 1 SYF2 splicing factor Asp PF00026.23 RJW71058.1 - 2.7e-29 102.6 0.0 3.4e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease RVP PF00077.20 RJW71058.1 - 0.14 12.5 0.0 0.79 10.1 0.0 2.2 2 1 0 2 2 2 0 Retroviral aspartyl protease Sod_Cu PF00080.20 RJW71059.1 - 1.8e-36 125.4 1.8 2.3e-36 125.1 1.8 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF5579 PF17742.1 RJW71060.1 - 0.031 13.8 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5579) Binary_toxB PF03495.14 RJW71060.1 - 0.2 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain Gpi1 PF05024.15 RJW71062.1 - 1.6e-20 74.0 8.2 1.2e-19 71.2 8.2 2.2 1 1 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) FDF PF09532.10 RJW71063.1 - 0.0063 17.4 3.7 0.02 15.7 3.8 1.9 1 1 0 1 1 1 1 FDF domain YjeF_N PF03853.15 RJW71063.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus TrmB PF01978.19 RJW71064.1 - 0.13 12.2 0.0 3.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DDE_Tnp_IS1595 PF12762.7 RJW71065.1 - 7.1e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 1 0 1 1 1 1 ISXO2-like transposase domain RRM_7 PF16367.5 RJW71066.1 - 1.5e-28 98.7 0.0 1.3e-27 95.7 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif CEBP_ZZ PF16366.5 RJW71066.1 - 1.3e-22 79.8 3.6 3.5e-22 78.4 3.6 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 RJW71066.1 - 2.6e-06 27.2 0.0 0.011 15.6 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 RJW71066.1 - 0.011 15.7 0.0 0.048 13.7 0.0 2.0 2 0 0 2 2 2 0 RNA binding domain zinc_ribbon_10 PF10058.9 RJW71066.1 - 3 7.7 5.8 7.5 6.4 5.8 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Serpin PF00079.20 RJW71067.1 - 2.1e-93 313.6 0.1 2.4e-93 313.4 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) MTABC_N PF16185.5 RJW71068.1 - 7.4e-58 195.9 11.2 9.5e-58 195.5 11.2 1.1 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region DUF4293 PF14126.6 RJW71068.1 - 0.015 15.6 3.8 0.015 15.6 3.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2070 PF09843.9 RJW71068.1 - 5.1 5.3 13.2 7.1 4.8 13.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DM PF00751.18 RJW71069.1 - 8.1e-29 99.3 31.6 2.3e-14 53.0 14.1 2.6 2 0 0 2 2 2 2 DM DNA binding domain zf-C3HC PF07967.13 RJW71069.1 - 0.66 10.0 6.4 0.1 12.6 0.4 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like HSP20 PF00011.21 RJW71071.1 - 1.8e-13 50.5 0.0 1.5e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ABC_tran PF00005.27 RJW71076.1 - 1.2e-47 161.8 0.0 3.6e-34 118.2 0.0 2.3 1 1 1 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RJW71076.1 - 3.2e-28 99.2 7.0 4.5e-28 98.7 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RJW71076.1 - 9.6e-09 35.0 0.9 1.7e-06 27.6 0.9 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RJW71076.1 - 6.3e-05 22.9 0.0 0.0005 20.0 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 RJW71076.1 - 0.0018 18.7 0.3 0.0052 17.2 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RJW71076.1 - 0.0051 16.5 0.1 0.017 14.8 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 RJW71076.1 - 0.014 15.4 0.2 0.57 10.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RepB-RCR_reg PF10723.9 RJW71076.1 - 0.028 14.3 0.0 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Replication regulatory protein RepB AAA_22 PF13401.6 RJW71076.1 - 0.043 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RJW71076.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 RJW71076.1 - 0.046 13.9 0.2 16 5.8 0.2 3.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 RJW71076.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.13 RJW71076.1 - 0.083 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.17 RJW71076.1 - 0.087 12.9 0.3 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain DUF4129 PF13559.6 RJW71076.1 - 0.13 12.6 2.1 15 5.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) YebG PF07130.12 RJW71076.1 - 0.14 12.0 0.0 34 4.4 0.0 2.7 2 0 0 2 2 2 0 YebG protein DPPIV_rep PF18811.1 RJW71076.1 - 3.6 7.6 5.5 29 4.8 0.5 2.5 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region CBP PF12192.8 RJW71077.1 - 0.19 11.9 3.4 0.3 11.3 3.4 1.2 1 0 0 1 1 1 0 Fungal calcium binding protein DGF-1_C PF11040.8 RJW71077.1 - 6.6 6.8 5.7 9.8 6.3 5.7 1.4 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus E1_DerP2_DerF2 PF02221.15 RJW71082.1 - 1.1e-06 29.1 0.1 2.2e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 ML domain Zip PF02535.22 RJW71083.1 - 7.4e-61 206.2 10.9 1.1e-60 205.7 10.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Ribosomal_L34 PF00468.17 RJW71083.1 - 0.047 13.7 0.4 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L34 DUF1772 PF08592.11 RJW71083.1 - 0.072 13.4 0.7 0.23 11.8 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) SWI-SNF_Ssr4 PF08549.10 RJW71084.1 - 0.43 9.1 1.9 9.9 4.7 0.1 2.0 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1750) NIF PF03031.18 RJW71086.1 - 1.3e-23 83.5 0.0 3.6e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BBIP10 PF14777.6 RJW71087.1 - 0.0044 16.6 0.1 0.23 11.0 0.0 2.4 2 0 0 2 2 2 2 Cilia BBSome complex subunit 10 Smg4_UPF3 PF03467.15 RJW71087.1 - 0.015 15.3 0.2 3.5 7.6 0.0 2.8 3 0 0 3 3 3 0 Smg-4/UPF3 family HOOK PF05622.12 RJW71089.1 - 8.6e-110 368.0 32.0 4.1e-89 299.6 22.4 2.1 2 0 0 2 2 2 2 HOOK protein CENP-F_leu_zip PF10473.9 RJW71089.1 - 0.00011 22.3 43.5 0.007 16.4 4.6 5.4 5 1 1 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phlebovirus_NSM PF07246.11 RJW71089.1 - 0.0004 19.8 2.1 0.0004 19.8 2.1 2.8 2 1 1 3 3 3 1 Phlebovirus nonstructural protein NS-M CH_2 PF06294.11 RJW71089.1 - 0.05 13.7 0.1 0.45 10.7 0.0 2.5 2 0 0 2 2 2 0 CH-like domain in sperm protein Shugoshin_N PF07558.11 RJW71089.1 - 1.5 8.7 5.3 6.1 6.8 0.7 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 RJW71089.1 - 1.5 9.0 62.1 0.14 12.4 2.7 5.6 2 1 2 5 5 5 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 RJW71089.1 - 4 7.6 28.9 0.28 11.3 1.5 5.9 5 1 1 6 6 6 0 bZIP transcription factor PHD PF00628.29 RJW71090.1 - 1.1e-12 47.6 19.3 5.1e-07 29.5 5.3 3.0 2 1 1 3 3 3 2 PHD-finger Requiem_N PF14051.6 RJW71090.1 - 1.5e-06 28.3 0.1 4.6e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. Cnd3 PF12719.7 RJW71091.1 - 5.6e-34 117.7 0.0 2.4e-33 115.6 0.0 2.0 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain PAN_1 PF00024.26 RJW71092.1 - 0.019 14.9 13.3 0.28 11.2 3.3 3.0 1 1 2 3 3 3 0 PAN domain GPI2 PF06432.11 RJW71094.1 - 3.6e-09 36.5 0.5 3.9e-09 36.4 0.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3810 PF12725.7 RJW71094.1 - 0.16 11.2 0.3 0.24 10.7 0.3 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Rotamase PF00639.21 RJW71095.1 - 2.4e-25 89.3 0.0 3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 RJW71095.1 - 1.2e-20 74.2 0.0 1.6e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 RJW71095.1 - 3.6e-09 36.6 2.3 2.5e-07 30.7 0.4 2.7 3 0 0 3 3 3 2 WW domain Rotamase_2 PF13145.6 RJW71095.1 - 0.00017 22.4 0.0 0.00023 22.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain FERM_C PF09380.10 RJW71098.1 - 5.2e-21 74.8 1.0 1.1e-20 73.8 1.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 RJW71098.1 - 2.2e-09 37.2 5.4 1.1e-08 35.0 5.4 2.3 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 RJW71098.1 - 0.0015 18.9 0.0 0.0046 17.3 0.0 1.8 1 0 0 1 1 1 1 FERM central domain Zein PF01559.16 RJW71098.1 - 2 7.9 15.9 0.11 12.1 2.2 2.9 3 0 0 3 3 3 0 Zein seed storage protein Pox_Ag35 PF03286.14 RJW71099.1 - 0.021 14.6 1.4 0.027 14.3 1.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RVT_1 PF00078.27 RJW71102.1 - 4.9e-46 157.0 0.5 1.5e-45 155.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SET PF00856.28 RJW71102.1 - 1.9e-16 60.9 1.6 4.5e-16 59.7 0.2 2.5 2 0 0 2 2 2 1 SET domain La PF05383.17 RJW71102.1 - 2.2e-15 56.5 0.2 5.8e-15 55.1 0.2 1.7 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 RJW71102.1 - 2.9e-12 46.5 0.2 9.1e-11 41.7 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif Exo_endo_phos_2 PF14529.6 RJW71102.1 - 2.4e-11 43.5 0.0 1.1e-10 41.4 0.0 2.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase preSET_CXC PF18264.1 RJW71102.1 - 3.8e-10 40.1 14.7 3.8e-10 40.1 14.7 2.7 2 0 0 2 2 2 1 CXC domain RRM_1 PF00076.22 RJW71102.1 - 0.00089 19.0 0.1 0.006 16.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L27_N PF09060.10 RJW71102.1 - 0.049 13.7 0.0 0.18 11.9 0.0 2.0 1 0 0 1 1 1 0 L27_N AKNA PF12443.8 RJW71102.1 - 0.21 12.2 0.3 11 6.7 0.0 2.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor SEC-C PF02810.15 RJW71103.1 - 0.17 11.9 1.0 0.17 11.9 1.0 2.2 2 0 0 2 2 2 0 SEC-C motif TPR_12 PF13424.6 RJW71105.1 - 0.00019 21.7 0.1 0.021 15.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW71105.1 - 0.0014 18.5 0.3 1.3 9.3 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.6 RJW71105.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Inp1 PF12634.7 RJW71106.1 - 0.086 12.8 0.1 0.086 12.8 0.1 2.8 3 0 0 3 3 3 0 Inheritance of peroxisomes protein 1 DUF1759 PF03564.15 RJW71107.1 - 5.7e-09 36.1 0.0 7.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Transferrin PF00405.17 RJW71107.1 - 0.026 13.7 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Transferrin FAP206 PF12018.8 RJW71109.1 - 1e-65 222.0 0.0 1.6e-65 221.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function Rap_GAP PF02145.15 RJW71111.1 - 7.1e-50 169.1 0.0 1.3e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP A_deaminase PF00962.22 RJW71112.1 - 4.4e-05 23.0 0.0 4.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase SCVP PF17619.2 RJW71113.1 - 0.018 15.9 0.0 0.025 15.4 0.0 1.2 1 0 0 1 1 1 0 Secreted clade V proteins FAM76 PF16046.5 RJW71113.1 - 0.094 12.1 1.9 0.13 11.6 1.9 1.2 1 0 0 1 1 1 0 FAM76 protein DFF40 PF09230.10 RJW71113.1 - 0.11 12.1 0.2 0.16 11.5 0.2 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Guanylate_kin PF00625.21 RJW71115.1 - 1.7e-23 83.2 0.0 3.3e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 RJW71115.1 - 5.6e-08 32.3 0.0 1.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 RJW71115.1 - 1.2e-05 25.6 0.1 2.7e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 RJW71115.1 - 2.9e-05 23.6 0.1 0.00011 21.8 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 RJW71115.1 - 0.0025 17.7 0.1 0.0064 16.3 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 RJW71115.1 - 0.054 13.4 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 PDZ domain Cwf_Cwc_15 PF04889.12 RJW71116.1 - 0.0019 18.0 13.6 0.0026 17.6 13.6 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 RJW71116.1 - 0.004 17.5 18.5 0.0059 17.0 18.5 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain CDC45 PF02724.14 RJW71116.1 - 0.026 12.8 5.6 0.029 12.7 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Afi1 PF07792.12 RJW71116.1 - 0.027 15.0 2.0 0.034 14.6 2.0 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NOA36 PF06524.12 RJW71116.1 - 0.033 13.5 18.9 0.043 13.1 18.9 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RJW71116.1 - 0.035 12.2 17.5 0.042 12.0 17.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 RJW71116.1 - 0.056 12.6 22.3 0.071 12.2 22.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 RJW71116.1 - 0.092 12.4 3.3 0.13 11.9 3.3 1.3 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 RJW71116.1 - 0.092 12.6 6.7 0.11 12.4 6.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 RJW71116.1 - 0.12 11.7 4.6 0.14 11.5 4.6 1.1 1 0 0 1 1 1 0 BUD22 DUF2796 PF10986.8 RJW71116.1 - 0.16 11.9 1.8 0.21 11.5 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Nop14 PF04147.12 RJW71116.1 - 0.18 10.0 7.6 0.2 9.9 7.6 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RJW71116.1 - 0.18 11.2 7.7 0.2 11.0 7.7 1.1 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.11 RJW71116.1 - 0.23 11.5 6.9 0.29 11.2 6.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 RJW71116.1 - 0.4 9.2 8.7 0.44 9.0 8.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 RJW71116.1 - 0.81 7.7 4.1 0.9 7.5 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SGT1 PF07093.11 RJW71116.1 - 0.93 7.9 6.3 1 7.7 6.3 1.1 1 0 0 1 1 1 0 SGT1 protein Utp14 PF04615.13 RJW71116.1 - 1 7.8 8.9 1.2 7.6 8.9 1.0 1 0 0 1 1 1 0 Utp14 protein DUF5577 PF17740.1 RJW71116.1 - 1.9 8.1 3.5 2.4 7.8 3.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5577) Rhabdo_ncap PF00945.18 RJW71116.1 - 6.7 5.5 6.2 8 5.2 6.2 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF2722 PF10846.8 RJW71116.1 - 6.9 5.5 5.8 7.9 5.3 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIF_alpha PF05793.12 RJW71116.1 - 9.1 4.7 10.5 12 4.4 10.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3295 PF11702.8 RJW71116.1 - 9.1 5.5 12.7 11 5.2 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DGC PF08859.11 RJW71117.1 - 0.078 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 DGC domain eIF3g PF12353.8 RJW71118.1 - 1e-32 113.1 3.1 1.6e-32 112.5 3.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 RJW71118.1 - 6.9e-18 64.2 0.0 1.4e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calpain_inhib PF00748.19 RJW71118.1 - 0.019 15.5 0.7 0.038 14.5 0.7 1.4 1 0 0 1 1 1 0 Calpain inhibitor Tctex-1 PF03645.13 RJW71119.1 - 8.9e-34 115.8 1.7 1e-33 115.6 1.7 1.0 1 0 0 1 1 1 1 Tctex-1 family Kinesin PF00225.23 RJW71121.1 - 1.1e-74 251.4 0.1 1.1e-74 251.4 0.1 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.6 RJW71121.1 - 5.6e-10 39.7 0.3 5.6e-10 39.7 0.3 3.6 3 2 1 4 4 4 1 Kinesin-associated microtubule-binding TcpS PF17456.2 RJW71121.1 - 0.27 11.3 4.4 1.3 9.1 2.4 2.7 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S FAA_hydro_N_2 PF18288.1 RJW71121.1 - 0.54 10.7 2.8 1.7 9.1 0.5 3.1 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 AMPK1_CBM PF16561.5 RJW71122.1 - 5e-34 116.4 0.5 7.9e-34 115.7 0.5 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 RJW71122.1 - 1.1e-24 86.4 1.7 2.3e-24 85.5 1.7 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 RJW71122.1 - 0.0031 18.1 0.1 0.0055 17.3 0.1 1.3 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_48 PF02922.18 RJW71122.1 - 0.015 15.6 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Peptidase_S28 PF05577.12 RJW71123.1 - 1.4e-09 37.3 0.0 1.5e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Cohesin_HEAT PF12765.7 RJW71123.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion RVT_1 PF00078.27 RJW71124.1 - 1.5e-30 106.3 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arf PF00025.21 RJW71126.1 - 3.1e-51 173.3 0.5 3.7e-42 143.7 0.2 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 RJW71126.1 - 1.1e-11 44.6 0.7 4.4e-06 26.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 RJW71126.1 - 9.6e-11 41.9 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 RJW71126.1 - 2e-07 30.6 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 RJW71126.1 - 5.6e-07 29.3 0.0 1.5e-06 28.0 0.0 1.6 1 1 1 2 2 2 1 Ras family MMR_HSR1 PF01926.23 RJW71126.1 - 8.3e-06 25.9 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RJW71126.1 - 1.9e-05 24.2 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 RJW71126.1 - 0.0036 16.7 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein UbiA PF01040.18 RJW71127.1 - 3.1e-36 125.0 8.9 4.5e-36 124.4 8.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3487 PF11990.8 RJW71127.1 - 1.5 8.8 4.3 0.76 9.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) IFT81_CH PF18383.1 RJW71128.1 - 3.2e-26 92.0 2.3 4.9e-26 91.4 0.1 2.5 2 0 0 2 2 2 1 Intraflagellar transport 81 calponin homology domain FAD_SOX PF18371.1 RJW71128.1 - 0.039 14.3 1.1 0.31 11.4 0.1 3.0 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase KxDL PF10241.9 RJW71128.1 - 0.043 14.1 0.6 0.043 14.1 0.6 6.3 6 2 1 7 7 7 0 Uncharacterized conserved protein DUF948 PF06103.11 RJW71128.1 - 0.1 12.8 0.2 0.1 12.8 0.2 5.8 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 RJW71128.1 - 0.18 11.9 13.6 0.82 9.7 1.5 4.2 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 RJW71128.1 - 0.46 8.4 22.1 0.6 8.0 8.6 3.3 3 1 0 3 3 3 0 Prominin NPV_P10 PF05531.12 RJW71128.1 - 0.74 10.3 20.0 12 6.5 1.5 5.7 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 RJW71128.1 - 1.5 8.9 32.9 0.16 12.0 7.1 5.2 5 2 0 5 5 5 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 RJW71128.1 - 2.2 8.1 22.3 1 9.2 0.5 5.0 4 2 1 5 5 5 0 Sec34-like family Tma16 PF11176.8 RJW71128.1 - 2.9 7.8 23.5 0.082 12.8 2.3 3.3 3 0 0 3 3 3 0 Translation machinery-associated protein 16 GAS PF13851.6 RJW71128.1 - 9 5.6 52.5 0.014 14.7 14.1 4.7 4 1 0 5 5 5 0 Growth-arrest specific micro-tubule binding Med31 PF05669.12 RJW71129.1 - 2.5e-36 123.6 4.8 2.5e-36 123.6 4.8 1.4 2 0 0 2 2 2 1 SOH1 Img2 PF05046.14 RJW71130.1 - 7.3e-24 83.9 0.0 1.1e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) DUF4739 PF15893.5 RJW71130.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) HEPN_Toprim_N PF18871.1 RJW71130.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 HLH PF00010.26 RJW71134.1 - 4.4e-08 33.0 4.0 4.4e-08 33.0 4.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain LZ_Tnp_IS481 PF13011.6 RJW71134.1 - 0.033 14.7 0.3 0.17 12.5 0.1 2.2 1 1 1 2 2 2 0 leucine-zipper of insertion element IS481 CRS1_YhbY PF01985.21 RJW71134.1 - 0.034 14.3 0.9 0.088 13.0 0.2 1.9 1 1 1 2 2 2 0 CRS1 / YhbY (CRM) domain HEAT_2 PF13646.6 RJW71136.1 - 2.4e-11 43.9 1.5 7.9e-05 23.0 0.0 3.8 1 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 RJW71136.1 - 8.2e-09 35.0 6.7 2.5 8.6 0.0 6.2 5 0 0 5 5 5 4 HEAT repeat UVR PF02151.19 RJW71136.1 - 7.5e-06 25.5 1.6 8.2e-06 25.4 0.1 1.9 2 0 0 2 2 2 1 UvrB/uvrC motif CLASP_N PF12348.8 RJW71136.1 - 0.0016 18.1 0.5 0.23 11.0 0.3 3.9 2 1 0 2 2 2 1 CLASP N terminal NUC130_3NT PF08158.12 RJW71136.1 - 0.0036 17.6 0.4 3 8.2 0.1 3.6 3 0 0 3 3 3 1 NUC130/3NT domain Cnd1 PF12717.7 RJW71136.1 - 0.004 17.2 0.8 2.6 8.1 0.1 3.6 1 1 3 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vitellogenin_N PF01347.22 RJW71136.1 - 0.068 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein amino terminal region DM PF00751.18 RJW71137.1 - 4.7e-21 74.4 11.0 7.9e-21 73.7 11.0 1.4 1 0 0 1 1 1 1 DM DNA binding domain Pkinase_Tyr PF07714.17 RJW71138.1 - 2.9e-78 262.7 0.0 4e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW71138.1 - 5.2e-42 144.0 0.0 7.3e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PBD PF00786.28 RJW71138.1 - 0.0022 18.3 0.2 0.005 17.2 0.2 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 RJW71138.1 - 0.0057 16.0 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH3_9 PF14604.6 RJW71138.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SAM_2 PF07647.17 RJW71138.1 - 0.091 12.9 0.0 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Kdo PF06293.14 RJW71138.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.27 RJW71139.1 - 3e-07 30.2 0.0 5.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GPI2 PF06432.11 RJW71139.1 - 4e-05 23.2 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase zf-C2H2 PF00096.26 RJW71140.1 - 7.6e-22 76.5 58.3 0.00028 21.2 3.3 8.6 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW71140.1 - 3.1e-19 68.0 57.7 0.0022 18.7 2.3 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2HC_2 PF13913.6 RJW71140.1 - 2.7e-10 39.9 29.5 0.011 15.6 0.0 6.9 6 0 0 6 6 6 4 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 RJW71140.1 - 2.6e-09 37.1 62.4 0.0059 17.0 1.0 9.9 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW71140.1 - 2.1e-07 30.8 44.0 0.043 13.8 0.6 8.4 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW71140.1 - 2.1e-05 24.2 33.8 0.043 13.6 0.4 6.6 7 0 0 7 7 7 4 zinc-finger C2H2-type zf-met PF12874.7 RJW71140.1 - 0.14 12.6 43.9 2.1 8.9 2.0 8.5 8 1 0 8 8 8 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 RJW71140.1 - 0.25 11.5 31.0 1.6 8.9 4.2 6.9 4 2 4 8 8 8 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 RJW71140.1 - 0.36 11.5 32.8 0.73 10.5 12.1 4.9 2 2 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 RJW71140.1 - 0.52 10.7 0.1 0.52 10.7 0.1 7.8 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 RJW71140.1 - 1.1 9.4 37.2 13 6.0 0.1 7.3 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_recom PF13408.6 RJW71140.1 - 2.1 8.9 32.2 1.9 9.1 5.3 5.5 2 2 3 6 6 6 0 Recombinase zinc beta ribbon domain FYVE PF01363.21 RJW71140.1 - 6.2 7.0 46.8 22 5.3 0.7 6.9 2 2 3 6 6 6 0 FYVE zinc finger zf_UBZ PF18439.1 RJW71140.1 - 6.6 6.4 28.3 2.3 7.9 0.5 7.3 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger YacG PF03884.14 RJW71140.1 - 7.8 6.3 15.2 0.044 13.5 4.8 2.8 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG RICTOR_phospho PF14665.6 RJW71143.1 - 0.54 10.6 9.1 0.62 10.4 0.5 3.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site PAS_3 PF08447.12 RJW71144.1 - 3.2e-09 36.9 0.0 8.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 RJW71144.1 - 0.0077 16.4 0.1 0.18 12.0 0.0 2.5 2 0 0 2 2 2 1 PAS domain RT_RNaseH_2 PF17919.1 RJW71145.1 - 6.3e-10 39.0 0.0 1.3e-08 34.8 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW71145.1 - 1.2e-07 32.0 0.0 9.7e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Ufd2P_core PF10408.9 RJW71146.1 - 4.3e-173 577.3 0.8 4.4e-173 577.3 0.1 1.4 2 0 0 2 2 2 1 Ubiquitin elongating factor core MRP-63 PF14978.6 RJW71148.1 - 2.9e-09 37.4 0.2 4.2e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 RyR PF02026.16 RJW71148.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 RyR domain Pkinase_Tyr PF07714.17 RJW71149.1 - 1.7e-53 181.5 0.0 2.8e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW71149.1 - 1.9e-49 168.4 0.0 2.9e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 RJW71149.1 - 3.5e-06 26.1 0.0 7.1e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF3037 PF11236.8 RJW71150.1 - 0.15 12.5 0.3 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) YbjM PF11045.8 RJW71151.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae A_deaminase PF00962.22 RJW71156.1 - 1.1e-60 205.7 0.0 1.4e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase ATPgrasp_N PF18130.1 RJW71156.1 - 0.018 15.6 0.1 0.067 13.7 0.1 2.1 1 0 0 1 1 1 0 ATP-grasp N-terminal domain Amidohydro_1 PF01979.20 RJW71156.1 - 0.026 13.9 0.1 0.15 11.3 0.1 2.0 2 0 0 2 2 2 0 Amidohydrolase family Linocin_M18 PF04454.12 RJW71156.1 - 0.058 12.7 0.1 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Encapsulating protein for peroxidase ABC2_membrane_3 PF12698.7 RJW71157.1 - 9.8 5.2 14.2 15 4.6 14.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MFS_1 PF07690.16 RJW71159.1 - 2.4e-17 62.9 36.7 1.1e-16 60.7 19.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Spore_III_AF PF09581.10 RJW71159.1 - 0.034 14.2 0.0 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DUF3742 PF12553.8 RJW71159.1 - 0.051 13.7 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) DUF4229 PF14012.6 RJW71159.1 - 0.44 10.7 0.0 0.44 10.7 0.0 4.1 5 1 0 5 5 5 0 Protein of unknown function (DUF4229) DSPc PF00782.20 RJW71160.1 - 7.2e-33 113.2 0.0 1.1e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 RJW71160.1 - 0.00026 21.5 0.0 0.00075 20.0 0.0 1.8 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 RJW71160.1 - 0.00026 20.6 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 RJW71160.1 - 0.002 18.4 0.1 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 Rit1 DUSP-like domain Baculo_IE-1 PF05290.11 RJW71160.1 - 0.027 14.4 0.2 7.3 6.5 0.0 3.0 4 0 0 4 4 4 0 Baculovirus immediate-early protein (IE-0) PTPlike_phytase PF14566.6 RJW71160.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate LRR_8 PF13855.6 RJW71161.1 - 2.5e-12 46.4 10.1 2.6e-07 30.3 0.4 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RJW71161.1 - 5.1e-10 39.4 7.8 4.8e-05 23.6 0.4 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW71161.1 - 0.0059 17.0 11.3 11 7.0 0.3 5.2 4 0 0 4 4 4 2 Leucine Rich Repeat DUF782 PF05614.11 RJW71162.1 - 0.12 12.8 0.6 0.45 10.9 0.0 2.0 1 1 0 2 2 2 0 Circovirus protein of unknown function (DUF782) WAPL PF07814.13 RJW71164.1 - 1.2e-58 198.7 0.1 6.6e-58 196.2 0.1 2.1 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Cwf_Cwc_15 PF04889.12 RJW71164.1 - 0.0024 17.6 17.2 0.0024 17.6 17.2 3.9 4 0 0 4 4 4 2 Cwf15/Cwc15 cell cycle control protein NPR3 PF03666.13 RJW71164.1 - 0.37 9.5 15.0 0.007 15.2 6.2 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RVT_1 PF00078.27 RJW71166.1 - 2.1e-17 63.4 0.0 4.1e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_2 PF00152.20 RJW71167.1 - 1.4e-75 254.3 0.2 1.8e-75 253.9 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RJW71167.1 - 6.3e-06 26.1 0.1 1.2e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RJW71167.1 - 1.6e-05 24.5 0.5 0.17 11.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Cystatin PF00031.21 RJW71169.1 - 1.8e-18 66.6 19.8 0.003 17.8 0.0 8.8 9 0 0 9 9 9 5 Cystatin domain PDCD7 PF16021.5 RJW71170.1 - 1.7e-13 50.4 16.2 5.1e-12 45.5 1.9 3.5 2 2 0 2 2 2 2 Programmed cell death protein 7 WD40 PF00400.32 RJW71170.1 - 2.6 9.1 10.2 4.8 8.2 1.2 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat HLH PF00010.26 RJW71173.1 - 2.9e-12 46.3 0.7 2.9e-12 46.3 0.7 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RVT_1 PF00078.27 RJW71174.1 - 1.3e-21 77.1 0.1 2.2e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) COG2 PF06148.11 RJW71175.1 - 7.5e-32 110.2 2.9 7.5e-32 110.2 2.9 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 UPA_2 PF17809.1 RJW71175.1 - 0.016 15.1 0.1 0.037 13.9 0.1 1.6 1 0 0 1 1 1 0 UPA domain Vps51 PF08700.11 RJW71175.1 - 0.031 14.3 0.5 0.14 12.2 0.3 2.4 1 1 0 1 1 1 0 Vps51/Vps67 Vps54_N PF10475.9 RJW71175.1 - 1.8 7.8 9.0 0.041 13.2 0.4 2.4 3 0 0 3 3 3 0 Vacuolar-sorting protein 54, of GARP complex NPV_P10 PF05531.12 RJW71175.1 - 3.8 8.0 5.2 46 4.6 0.1 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RRM_1 PF00076.22 RJW71176.1 - 5.9e-06 26.0 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fip1 PF05182.13 RJW71177.1 - 3.1e-21 74.6 0.6 5.1e-21 73.9 0.6 1.4 1 0 0 1 1 1 1 Fip1 motif RVT_1 PF00078.27 RJW71178.1 - 1.1e-12 48.0 0.0 1.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HCNGP PF07818.13 RJW71179.1 - 5e-28 97.6 0.4 1.1e-27 96.5 0.4 1.7 1 0 0 1 1 1 1 HCNGP-like protein WDCP PF15390.6 RJW71179.1 - 0.13 10.7 1.5 0.18 10.2 1.5 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family EF-hand_1 PF00036.32 RJW71180.1 - 9.7e-38 124.9 14.0 1.4e-09 36.8 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW71180.1 - 1.8e-30 105.2 10.3 6.8e-15 55.3 2.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW71180.1 - 1.3e-28 96.4 9.3 9.2e-09 34.5 0.3 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RJW71180.1 - 1.9e-26 91.6 10.7 3.4e-14 52.4 0.9 3.4 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW71180.1 - 1.8e-24 84.1 11.4 3.7e-06 26.2 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RJW71180.1 - 6.7e-11 42.3 1.0 6.3e-07 29.6 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RJW71180.1 - 4e-09 36.8 3.2 0.00072 19.9 0.5 2.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW71180.1 - 8.8e-07 28.8 7.2 0.0026 17.7 0.9 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 RJW71180.1 - 4.9e-06 26.6 1.0 0.067 13.1 0.0 2.5 2 1 1 3 3 3 2 Tellurite resistance protein TerB EF-hand_10 PF14788.6 RJW71180.1 - 9.4e-06 25.4 1.3 0.079 12.8 0.1 2.5 2 0 0 2 2 2 2 EF hand Caleosin PF05042.13 RJW71180.1 - 0.0022 17.9 6.3 0.17 11.8 0.4 3.4 2 2 1 4 4 4 2 Caleosin related protein DUF3349 PF11829.8 RJW71180.1 - 0.0045 17.7 0.6 5.7 7.8 0.0 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF3349) Fe_hyd_lg_C PF02906.14 RJW71180.1 - 0.0074 16.0 4.2 1.6 8.4 0.4 2.7 1 1 2 3 3 3 2 Iron only hydrogenase large subunit, C-terminal domain ClpS PF02617.17 RJW71180.1 - 0.011 15.4 0.0 0.064 13.0 0.0 2.0 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS DUF2666 PF10869.8 RJW71180.1 - 0.012 15.8 1.8 5.5 7.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2666) EF-hand_14 PF17959.1 RJW71180.1 - 0.03 14.7 1.3 0.18 12.2 0.5 2.2 2 0 0 2 2 2 0 EF-hand domain OST-HTH PF12872.7 RJW71180.1 - 0.048 13.5 0.0 15 5.5 0.0 2.8 2 1 1 3 3 3 0 OST-HTH/LOTUS domain RNA_pol_Rpb4 PF03874.16 RJW71180.1 - 0.063 13.6 1.8 0.9 9.9 1.8 2.2 1 1 0 1 1 1 0 RNA polymerase Rpb4 SurA_N_3 PF13624.6 RJW71180.1 - 0.065 13.0 0.1 0.1 12.4 0.1 1.4 1 1 0 1 1 1 0 SurA N-terminal domain FRB_dom PF08771.11 RJW71180.1 - 0.069 13.6 0.2 0.42 11.0 0.0 2.2 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain EF-hand_11 PF08976.11 RJW71180.1 - 0.11 13.4 0.6 3 8.8 0.1 2.2 1 1 0 2 2 2 0 EF-hand domain SpaA PF17802.1 RJW71180.1 - 0.19 12.1 0.4 0.79 10.1 0.4 2.1 1 1 0 1 1 1 0 Prealbumin-like fold domain MIG-14_Wnt-bd PF06664.12 RJW71181.1 - 3.4e-77 259.5 13.5 5.5e-77 258.9 13.5 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Bromodomain PF00439.25 RJW71183.1 - 1.9e-06 27.8 0.0 4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.6 RJW71183.1 - 0.0021 18.3 2.0 0.0021 18.3 2.0 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RJW71183.1 - 0.0081 16.3 1.8 0.023 14.8 1.8 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 RJW71183.1 - 0.021 14.7 7.8 0.036 14.0 6.1 2.3 1 1 1 2 2 2 0 PHD-finger Hamartin PF04388.12 RJW71183.1 - 0.57 8.8 14.8 0.91 8.1 14.8 1.4 1 0 0 1 1 1 0 Hamartin protein C1_1 PF00130.22 RJW71183.1 - 3.7 7.5 14.8 0.056 13.3 6.8 2.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LRR_4 PF12799.7 RJW71184.1 - 0.029 14.8 0.7 0.75 10.3 0.2 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Integrase_H2C2 PF17921.1 RJW71186.1 - 5.4e-14 52.0 1.0 5.4e-14 52.0 1.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 RJW71186.1 - 7.3e-10 39.1 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RJW71186.1 - 0.0018 18.4 2.2 0.0086 16.3 0.4 2.3 2 0 0 2 2 2 1 H2C2 zinc finger NIPSNAP PF07978.13 RJW71187.1 - 2e-30 105.0 0.0 2.8e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 NIPSNAP Homeodomain PF00046.29 RJW71190.1 - 1.3e-23 82.5 6.1 1.3e-23 82.5 6.1 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RJW71190.1 - 0.0002 21.2 0.1 0.00058 19.7 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain LRR_4 PF12799.7 RJW71191.1 - 0.0064 16.9 6.7 9.1 6.9 0.7 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW71191.1 - 0.0068 16.8 5.8 0.33 11.7 0.4 4.0 3 1 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 RJW71191.1 - 0.036 14.1 8.0 2.2 8.6 0.4 3.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 RJW71191.1 - 6.7 6.6 9.5 10 6.0 0.2 3.7 3 1 0 3 3 3 0 Leucine rich repeat KxDL PF10241.9 RJW71192.1 - 3.7e-20 72.0 0.3 6.9e-20 71.1 0.3 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein Cation_efflux PF01545.21 RJW71192.1 - 1e-12 48.2 11.3 3.2e-12 46.6 11.3 1.8 1 1 0 1 1 1 1 Cation efflux family Spc29 PF17082.5 RJW71192.1 - 0.051 13.4 0.3 0.082 12.7 0.3 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 Sec20 PF03908.13 RJW71193.1 - 1.2e-07 31.5 1.7 2.2e-07 30.7 0.4 2.0 2 0 0 2 2 2 1 Sec20 DUF3450 PF11932.8 RJW71193.1 - 0.094 12.0 4.7 0.61 9.3 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) CC2-LZ PF16516.5 RJW71193.1 - 0.17 12.3 1.8 0.3 11.5 0.1 2.2 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator wnt PF00110.19 RJW71194.1 - 1.6e-63 215.2 10.6 2.4e-39 135.8 14.0 2.1 2 0 0 2 2 2 2 wnt family PDEase_I PF00233.19 RJW71196.1 - 2.3e-68 230.5 0.4 3.8e-68 229.7 0.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ThrE PF06738.12 RJW71196.1 - 0.2 11.0 0.0 0.46 9.8 0.0 1.6 2 0 0 2 2 2 0 Putative threonine/serine exporter Galactosyl_T PF01762.21 RJW71197.1 - 8.1e-06 25.8 0.0 0.0046 16.8 0.1 2.2 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 RJW71197.1 - 0.0012 18.4 0.4 0.012 15.0 0.4 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RJW71198.1 - 4.4e-09 36.4 0.0 4.9e-06 26.5 0.0 2.6 3 0 0 3 3 3 2 Galactosyltransferase Fringe PF02434.16 RJW71198.1 - 0.0046 16.4 0.4 0.22 11.0 0.4 2.3 1 1 0 1 1 1 1 Fringe-like DUF4854 PF16146.5 RJW71198.1 - 0.11 12.8 0.2 0.31 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Galactosyl_T PF01762.21 RJW71199.1 - 3.8e-06 26.9 0.0 0.00074 19.4 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 RJW71199.1 - 0.00026 20.5 0.4 0.0051 16.3 0.4 2.1 1 1 0 1 1 1 1 Fringe-like DUF2826 PF11442.8 RJW71199.1 - 0.048 13.5 0.2 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2826) zf-C2H2_aberr PF17017.5 RJW71200.1 - 0.026 14.7 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger tRNA-synt_1 PF00133.22 RJW71201.1 - 5.2e-99 332.1 0.0 1.1e-91 308.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RJW71201.1 - 6.1e-11 42.5 0.1 1.3e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RJW71201.1 - 7.3e-07 28.3 0.0 0.015 14.1 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 RJW71201.1 - 0.031 13.8 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 RJW71201.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF4454 PF14628.6 RJW71201.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) NHL PF01436.21 RJW71204.1 - 1.6e-09 37.3 3.0 1.6e-07 31.0 0.1 4.6 5 0 0 5 5 5 1 NHL repeat GDA1_CD39 PF01150.17 RJW71205.1 - 1.3e-66 225.0 0.0 2.4e-66 224.2 0.0 1.3 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family BTP PF05232.12 RJW71205.1 - 0.28 11.3 2.1 0.59 10.2 2.1 1.5 1 0 0 1 1 1 0 Chlorhexidine efflux transporter zinc_ribbon_16 PF17034.5 RJW71206.1 - 4.9e-11 42.9 13.1 8.9e-06 25.9 0.3 3.0 2 1 1 3 3 3 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 RJW71206.1 - 0.0041 16.7 7.3 0.0041 16.7 7.3 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type dCMP_cyt_deam_1 PF00383.23 RJW71207.1 - 2.5e-17 62.6 1.6 5.3e-17 61.5 1.4 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RJW71207.1 - 1.8e-14 53.6 0.0 3.9e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase NAD1 PF18778.1 RJW71207.1 - 0.04 14.0 0.2 0.081 13.0 0.2 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 SNAD4 PF18750.1 RJW71207.1 - 0.043 13.9 0.2 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 RJW71207.1 - 0.058 13.5 1.2 0.6 10.2 0.8 2.5 2 1 0 2 2 2 0 Bd3614-like deaminase APOBEC2 PF18772.1 RJW71207.1 - 0.063 13.3 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 APOBEC2 Tubulin PF00091.25 RJW71208.1 - 2.2e-67 227.1 0.0 3e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW71208.1 - 5.9e-52 175.1 0.0 9.4e-52 174.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW71208.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pkinase PF00069.25 RJW71209.1 - 1.1e-76 257.8 0.0 1.5e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW71209.1 - 2.9e-45 154.6 0.0 4.2e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 RJW71209.1 - 3e-11 42.9 0.0 6.8e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 RJW71209.1 - 2.9e-07 30.1 0.0 4.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA PF00627.31 RJW71209.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Kdo PF06293.14 RJW71209.1 - 0.0021 17.4 0.1 0.004 16.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RJW71209.1 - 0.014 15.0 0.4 0.025 14.2 0.4 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 RJW71209.1 - 0.022 13.7 0.1 0.041 12.8 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain UBA_3 PF09288.10 RJW71209.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain FTA2 PF13095.6 RJW71209.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 RJW71209.1 - 0.17 11.4 0.7 0.43 10.1 0.1 1.7 1 1 0 2 2 2 0 PhoP regulatory network protein YrbL Ion_trans PF00520.31 RJW71210.1 - 1.3e-31 109.7 15.5 5.1e-31 107.8 15.4 1.8 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RJW71210.1 - 2.7e-29 101.3 0.0 1.2e-28 99.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 RJW71210.1 - 6.3e-08 32.5 0.8 6.3e-08 32.5 0.8 2.2 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 RJW71210.1 - 6.7 5.3 10.6 1.2 7.7 5.5 2.0 2 0 0 2 2 2 0 Polycystin cation channel Ion_trans PF00520.31 RJW71212.1 - 0.2 10.9 0.2 0.25 10.5 0.2 1.1 1 0 0 1 1 1 0 Ion transport protein Cadherin PF00028.17 RJW71213.1 - 1.5e-87 288.1 0.4 5.9e-19 68.3 0.0 11.1 7 5 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RJW71213.1 - 1.3e-12 47.4 0.3 9e-06 25.4 0.1 5.5 5 1 0 5 5 5 2 Cadherin-like Cadherin_3 PF16184.5 RJW71213.1 - 4.4e-09 36.3 4.4 0.0077 16.2 0.0 5.8 6 0 0 6 6 6 3 Cadherin-like RET_CLD1 PF17756.1 RJW71213.1 - 0.00036 20.8 0.0 0.18 12.1 0.0 3.9 4 0 0 4 4 4 1 RET Cadherin like domain 1 Cadherin_4 PF17803.1 RJW71213.1 - 0.063 13.9 0.1 0.063 13.9 0.1 4.5 5 0 0 5 5 5 0 Bacterial cadherin-like domain SRF-TF PF00319.18 RJW71214.1 - 3.2e-20 71.3 0.2 5.6e-20 70.6 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MAGUK_N_PEST PF10608.9 RJW71214.1 - 0.01 16.3 0.0 1.7 9.1 0.0 2.8 1 1 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK TPR_12 PF13424.6 RJW71215.1 - 3.4e-07 30.5 11.8 0.00045 20.5 0.6 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 RJW71215.1 - 0.0011 18.8 3.9 0.47 10.6 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RJW71215.1 - 0.0029 17.4 3.3 0.43 10.5 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 RJW71215.1 - 0.0039 17.2 5.5 0.035 14.2 0.7 3.3 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 RJW71215.1 - 0.0042 16.8 4.4 2.9 7.8 0.5 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW71215.1 - 0.02 15.0 16.0 0.33 11.3 1.2 6.0 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 RJW71215.1 - 0.13 12.5 16.8 7.1 7.0 1.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Izumo-Ig PF16706.5 RJW71216.1 - 8.7e-08 32.1 4.1 4.4 7.4 0.0 7.8 7 0 0 7 7 7 3 Izumo-like Immunoglobulin domain V-set PF07686.17 RJW71216.1 - 3e-07 30.6 12.2 3.2 8.0 0.1 8.4 8 0 0 8 8 8 4 Immunoglobulin V-set domain I-set PF07679.16 RJW71216.1 - 6.5e-05 22.9 6.0 11 6.2 0.0 6.5 6 0 0 6 6 6 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW71216.1 - 0.001 19.7 14.7 49 4.6 0.0 8.9 9 0 0 9 9 9 0 Immunoglobulin domain ig PF00047.25 RJW71216.1 - 0.0081 16.3 10.4 1.6 9.0 0.0 7.4 7 0 0 7 7 7 1 Immunoglobulin domain Ig_3 PF13927.6 RJW71217.1 - 0.0003 21.3 3.1 5.9 7.6 0.1 5.3 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 RJW71217.1 - 0.041 14.1 4.9 5.6 7.2 0.0 4.7 6 0 0 6 6 6 0 Immunoglobulin V-set domain QVR PF17064.5 RJW71218.1 - 0.0051 17.0 3.5 0.15 12.3 0.1 2.3 1 1 1 2 2 2 2 Sleepless protein Ly-6_related PF06579.12 RJW71218.1 - 0.05 13.9 2.8 0.12 12.6 2.7 1.7 1 1 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein Cupin_7 PF12973.7 RJW71218.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain RVT_1 PF00078.27 RJW71220.1 - 3.7e-47 160.7 0.5 2.5e-46 158.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW71220.1 - 9.1e-09 35.2 0.0 9.1e-08 32.0 0.0 2.6 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase 7tm_1 PF00001.21 RJW71223.1 - 8.3e-22 77.8 16.8 1.6e-21 76.9 16.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RJW71223.1 - 7.2e-05 22.7 14.5 7.2e-05 22.7 14.5 2.1 2 0 0 2 2 2 1 Olfactory receptor YqgB PF11036.8 RJW71223.1 - 0.23 11.2 1.3 7.3 6.4 0.0 3.1 3 0 0 3 3 3 0 Virulence promoting factor Synaptobrevin PF00957.21 RJW71223.1 - 0.38 10.6 0.0 0.38 10.6 0.0 3.2 4 0 0 4 4 4 0 Synaptobrevin Sensor PF13796.6 RJW71223.1 - 0.46 10.5 9.9 4.8 7.2 0.0 3.1 3 1 0 3 3 3 0 Putative sensor Orf78 PF06024.12 RJW71223.1 - 3.6 7.9 13.3 8.6 6.7 0.1 3.5 3 1 1 4 4 4 0 Orf78 (ac78) Nup88 PF10168.9 RJW71225.1 - 2.4e-39 134.8 11.4 1.9e-19 69.0 0.0 4.2 2 1 1 3 3 3 3 Nuclear pore component TPR_19 PF14559.6 RJW71229.1 - 2.3e-36 124.1 47.5 3.5e-06 27.4 0.6 13.9 9 2 4 14 14 14 11 Tetratricopeptide repeat TPR_14 PF13428.6 RJW71229.1 - 4.3e-20 70.7 36.5 0.00022 21.8 0.1 15.8 13 2 3 16 16 13 5 Tetratricopeptide repeat TPR_2 PF07719.17 RJW71229.1 - 6.6e-20 69.6 40.3 0.024 14.7 0.0 16.1 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_1 PF00515.28 RJW71229.1 - 3.8e-16 58.1 17.8 0.069 13.0 0.0 12.1 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.6 RJW71229.1 - 4.5e-15 56.0 28.5 0.0019 18.8 0.0 9.8 10 1 2 12 12 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 RJW71229.1 - 5.5e-14 51.1 34.1 0.0019 18.3 0.4 13.8 16 0 0 16 16 12 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW71229.1 - 1.3e-13 50.9 44.8 0.00012 22.2 0.5 11.7 8 3 3 11 11 11 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RJW71229.1 - 1.1e-11 43.9 22.3 0.27 11.3 0.0 13.0 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_12 PF13424.6 RJW71229.1 - 2.8e-11 43.5 56.9 0.011 16.0 0.1 12.1 9 5 3 13 13 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 RJW71229.1 - 2.4e-09 36.9 16.0 0.6 10.6 0.0 10.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 RJW71229.1 - 1.4e-08 34.8 36.2 0.099 13.3 0.0 14.0 16 0 0 16 16 12 2 Tetratricopeptide repeat TPR_4 PF07721.14 RJW71229.1 - 8.6e-08 32.1 6.2 23 6.0 0.0 8.9 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 RJW71229.1 - 3e-06 27.3 13.1 0.092 12.9 0.1 7.8 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 RJW71229.1 - 2.1e-05 23.9 23.1 0.13 11.4 0.6 6.6 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_21 PF09976.9 RJW71229.1 - 0.00013 21.7 25.9 0.13 11.9 0.1 7.2 6 1 0 7 7 7 2 Tetratricopeptide repeat-like domain RPN7 PF10602.9 RJW71229.1 - 0.00023 20.9 7.8 0.11 12.2 0.1 5.7 5 1 0 5 5 5 1 26S proteasome subunit RPN7 TPR_10 PF13374.6 RJW71229.1 - 0.0016 18.3 20.0 5.6 7.0 0.0 9.5 10 0 0 10 10 10 1 Tetratricopeptide repeat DUF4919 PF16266.5 RJW71229.1 - 0.003 17.6 2.9 0.4 10.6 0.0 4.3 3 1 1 4 4 4 1 Domain of unknown function (DUF4919) T6SS_VasJ PF16989.5 RJW71229.1 - 0.018 14.6 7.3 0.32 10.4 0.4 3.8 3 0 0 3 3 3 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ TPR_11 PF13414.6 RJW71229.1 - 0.077 12.7 21.2 0.57 9.9 0.0 9.7 11 1 1 12 12 12 0 TPR repeat HemY_N PF07219.13 RJW71229.1 - 0.39 10.9 4.3 2.6 8.3 0.0 4.2 4 1 0 4 4 3 0 HemY protein N-terminus BTAD PF03704.17 RJW71229.1 - 1.3 9.5 25.7 0.34 11.4 0.7 6.7 5 1 1 7 7 6 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 RJW71229.1 - 2.7 8.4 20.3 9.9 6.6 0.1 7.3 6 3 3 9 9 8 0 Tetratricopeptide repeat DUF3801 PF12687.7 RJW71230.1 - 0.036 14.1 3.0 0.062 13.4 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) GAS2 PF02187.17 RJW71232.1 - 2.2e-28 98.1 0.2 2.2e-28 98.1 0.2 1.9 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 RJW71232.1 - 1.7e-11 44.3 0.0 5.4e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 Calponin homology (CH) domain Guanylate_kin PF00625.21 RJW71233.1 - 1.3e-57 194.4 0.0 1.5e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase ABC_tran PF00005.27 RJW71233.1 - 7.8e-07 29.7 0.0 1.3e-06 29.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 RJW71233.1 - 1.4e-05 25.4 0.1 2.7e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RJW71233.1 - 2.5e-05 24.5 0.0 0.0017 18.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 RJW71233.1 - 5.8e-05 23.1 0.0 8.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 RJW71233.1 - 6.7e-05 23.4 0.0 0.00013 22.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RJW71233.1 - 0.00013 22.4 0.2 0.00052 20.4 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 RJW71233.1 - 0.00019 21.7 0.5 0.00071 19.9 0.1 2.2 2 1 0 2 2 1 1 RNA helicase RsgA_GTPase PF03193.16 RJW71233.1 - 0.00054 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 RJW71233.1 - 0.00088 18.8 0.0 0.0021 17.6 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 RJW71233.1 - 0.0013 18.7 0.1 0.0023 17.9 0.1 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 RJW71233.1 - 0.0018 18.9 1.9 0.011 16.2 1.9 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 RJW71233.1 - 0.0022 18.4 0.1 0.0049 17.3 0.0 1.9 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 RJW71233.1 - 0.0038 17.3 0.0 0.0075 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 RJW71233.1 - 0.0065 16.5 0.0 0.0089 16.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 RJW71233.1 - 0.02 14.7 0.2 0.099 12.4 0.1 1.9 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.15 RJW71233.1 - 0.023 13.5 0.1 0.047 12.5 0.1 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_5 PF07728.14 RJW71233.1 - 0.023 14.7 0.0 0.2 11.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 RJW71233.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 RJW71233.1 - 0.025 14.3 0.2 0.23 11.1 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain Cytidylate_kin PF02224.18 RJW71233.1 - 0.027 14.2 0.1 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 RJW71233.1 - 0.028 14.6 0.1 0.074 13.3 0.1 1.8 1 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RJW71233.1 - 0.049 14.0 0.1 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 RJW71233.1 - 0.052 12.8 0.0 0.11 11.7 0.0 1.7 1 1 0 1 1 1 0 Septin NB-ARC PF00931.22 RJW71233.1 - 0.055 12.6 0.0 0.13 11.4 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 RJW71233.1 - 0.059 12.7 0.4 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 RJW71233.1 - 0.061 13.2 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 RJW71233.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) dNK PF01712.19 RJW71233.1 - 0.077 12.8 0.4 0.96 9.3 0.4 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase PRK PF00485.18 RJW71233.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family fn3 PF00041.21 RJW71235.1 - 0 1106.6 49.8 5.8e-18 65.0 0.3 23.2 23 0 0 23 23 23 22 Fibronectin type III domain I-set PF07679.16 RJW71235.1 - 2.1e-174 566.1 0.0 1.2e-19 70.2 0.0 16.0 14 0 0 14 14 14 14 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW71235.1 - 9.7e-111 362.6 0.1 1e-15 58.1 0.0 14.3 14 0 0 14 14 13 12 Immunoglobulin domain Pkinase PF00069.25 RJW71235.1 - 5.8e-69 232.4 0.0 1e-68 231.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.6 RJW71235.1 - 1.9e-59 198.0 0.0 2.4e-13 50.2 0.1 14.6 14 0 0 14 14 14 7 Immunoglobulin domain ig PF00047.25 RJW71235.1 - 2.1e-45 152.8 2.1 2.3e-10 40.5 0.2 9.7 9 1 0 9 9 8 6 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RJW71235.1 - 1e-35 122.1 28.6 0.0018 18.8 0.0 21.0 23 0 0 23 23 21 8 Purple acid Phosphatase, N-terminal domain Pkinase_Tyr PF07714.17 RJW71235.1 - 5.5e-35 120.9 0.0 1.1e-34 119.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase V-set PF07686.17 RJW71235.1 - 8.7e-25 87.0 4.7 0.047 13.9 0.8 15.2 13 5 1 14 14 13 4 Immunoglobulin V-set domain Y_Y_Y PF07495.13 RJW71235.1 - 8.3e-12 44.9 0.1 13 5.8 0.0 10.5 12 0 0 12 12 8 0 Y_Y_Y domain C2-set_2 PF08205.12 RJW71235.1 - 3.5e-11 43.0 12.9 0.0052 16.8 0.0 7.9 8 0 0 8 8 7 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RJW71235.1 - 1.3e-09 37.9 0.5 9 6.4 0.0 8.9 10 0 0 10 10 8 0 Izumo-like Immunoglobulin domain CBM_4_9 PF02018.17 RJW71235.1 - 1e-07 32.3 2.3 0.71 10.1 0.0 9.5 9 0 0 9 9 9 1 Carbohydrate binding domain Ig_5 PF16681.5 RJW71235.1 - 4.1e-06 27.1 3.0 0.013 15.9 0.3 5.1 5 0 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RJW71235.1 - 5.1e-05 23.4 0.9 0.11 12.7 0.3 4.1 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 RJW71235.1 - 0.00032 20.9 1.3 26 5.1 0.0 7.6 9 1 0 9 9 7 0 Natural killer cell receptor 2B4 Kdo PF06293.14 RJW71235.1 - 0.00058 19.3 0.3 0.0012 18.2 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2369 PF10179.9 RJW71235.1 - 0.0026 18.1 0.0 42 4.6 0.0 7.4 11 0 0 11 11 7 0 Uncharacterised conserved protein (DUF2369) RcsC PF09456.10 RJW71235.1 - 0.0057 16.6 0.2 17 5.5 0.0 3.4 3 0 0 3 3 3 0 RcsC Alpha-Beta-Loop (ABL) Ig_C17orf99 PF17736.1 RJW71235.1 - 0.015 15.4 0.1 21 5.3 0.0 3.8 3 0 0 3 3 3 0 C17orf99 Ig domain Cadherin PF00028.17 RJW71235.1 - 0.018 15.5 1.0 94 3.6 0.0 6.8 7 0 0 7 7 5 0 Cadherin domain Adhesin_P1 PF03257.13 RJW71235.1 - 0.022 15.3 0.9 1.4 9.5 0.1 3.2 2 0 0 2 2 2 0 Mycoplasma adhesin P1 DUF3016 PF11454.8 RJW71235.1 - 0.032 14.0 0.0 5.3 6.8 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3016) DUF3146 PF11344.8 RJW71235.1 - 0.32 10.7 1.9 17 5.2 0.0 5.0 6 0 0 6 6 5 0 Protein of unknown function (DUF3146) CarboxypepD_reg PF13620.6 RJW71235.1 - 0.43 10.9 6.4 3.4 8.0 0.2 5.4 4 0 0 4 4 3 0 Carboxypeptidase regulatory-like domain WD40 PF00400.32 RJW71238.1 - 1.5e-07 32.0 4.6 0.018 15.9 0.3 5.0 5 1 0 5 5 5 2 WD domain, G-beta repeat zf-UBP PF02148.19 RJW71242.1 - 2.9e-14 53.1 0.3 3.9e-14 52.7 0.3 1.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_M1 PF01433.20 RJW71244.1 - 3.6e-42 144.4 0.0 6.5e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RJW71244.1 - 3.6e-27 94.7 0.2 7.3e-27 93.7 0.2 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 RJW71244.1 - 1.3e-25 90.6 0.0 1.8e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 RJW71244.1 - 0.051 13.2 0.2 0.12 12.0 0.2 1.6 1 1 0 1 1 1 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 RJW71244.1 - 0.11 12.9 1.4 1.9 8.9 1.4 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Hum_adeno_E3A PF05393.11 RJW71247.1 - 0.021 14.8 2.0 0.051 13.5 0.8 2.0 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein EphA2_TM PF14575.6 RJW71247.1 - 0.026 15.4 0.0 2 9.4 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Fibrinogen_C PF00147.18 RJW71247.1 - 0.21 11.4 0.2 0.41 10.4 0.2 1.4 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain LRR_6 PF13516.6 RJW71248.1 - 1.2e-22 78.0 19.4 0.00036 20.4 0.1 9.3 9 0 0 9 9 9 6 Leucine Rich repeat LRR_1 PF00560.33 RJW71248.1 - 9.7e-07 28.5 9.9 5.1 8.0 0.0 8.2 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_4 PF12799.7 RJW71248.1 - 0.00029 21.1 22.5 0.63 10.5 0.2 6.4 1 1 6 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW71248.1 - 0.0028 17.4 19.5 4.3 7.2 0.5 7.3 3 2 4 7 7 7 4 Leucine rich repeat EF-hand_7 PF13499.6 RJW71248.1 - 0.13 12.7 0.0 0.46 11.0 0.1 2.0 1 1 1 2 2 2 0 EF-hand domain pair Fe-S_assembly PF04384.13 RJW71249.1 - 0.00014 22.4 0.2 0.69 10.6 0.0 2.4 2 0 0 2 2 2 2 Iron-sulphur cluster assembly Strep_pep PF14404.6 RJW71249.1 - 0.09 13.0 0.0 26 5.2 0.0 2.5 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species DUF5353 PF17304.2 RJW71249.1 - 0.096 12.5 0.0 21 4.9 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5353) MdcG PF10620.9 RJW71249.1 - 0.12 12.1 0.0 19 5.0 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG UNC119_bdg PF15435.6 RJW71249.1 - 0.21 11.1 0.3 20 4.6 0.0 2.1 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue 6PF2K PF01591.18 RJW71251.1 - 1.5e-55 187.9 0.2 2.2e-55 187.4 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 RJW71251.1 - 1.2e-38 132.8 0.0 2.1e-38 132.0 0.0 1.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) CAP PF00188.26 RJW71252.1 - 9.2e-22 78.2 0.0 6e-21 75.6 0.0 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family DUF716 PF04819.12 RJW71257.1 - 0.00011 21.8 5.7 0.0003 20.5 5.7 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF716) Homeodomain PF00046.29 RJW71258.1 - 7.1e-19 67.4 9.6 7.9e-19 67.3 7.2 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RJW71258.1 - 0.041 13.8 0.2 0.098 12.6 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain CENP-B_dimeris PF09026.10 RJW71259.1 - 0.014 15.7 20.5 0.02 15.3 20.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 RJW71259.1 - 0.067 13.2 5.8 0.071 13.1 5.8 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 RJW71259.1 - 0.2 10.8 19.4 0.22 10.7 19.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 RJW71259.1 - 0.21 10.1 5.5 0.19 10.2 5.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 RJW71259.1 - 0.28 10.8 2.8 0.33 10.6 2.8 1.2 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 RJW71259.1 - 0.33 9.0 15.2 0.31 9.1 15.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cnd2 PF05786.14 RJW71259.1 - 0.53 8.9 9.0 0.5 9.0 9.0 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 NOA36 PF06524.12 RJW71259.1 - 2 7.7 22.8 2.4 7.4 22.8 1.0 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 RJW71259.1 - 2.8 7.8 10.9 3 7.7 10.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region GCIP PF13324.6 RJW71259.1 - 2.8 7.5 7.7 3.1 7.3 7.7 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 RJW71259.1 - 3 5.9 10.7 3.1 5.9 10.7 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RJW71259.1 - 3.2 7.1 10.5 3.4 7.0 10.5 1.0 1 0 0 1 1 1 0 SDA1 Utp14 PF04615.13 RJW71259.1 - 3.7 6.0 7.4 3.7 6.0 7.4 1.0 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 RJW71259.1 - 3.9 6.7 9.4 4.1 6.6 9.4 1.0 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 RJW71259.1 - 5.7 5.4 9.7 5.8 5.4 9.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 RJW71259.1 - 7.6 6.2 22.8 10 5.8 22.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EBV-NA3 PF05009.12 RJW71259.1 - 7.8 5.9 5.2 9 5.7 5.2 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Transket_pyr PF02779.24 RJW71260.1 - 1.2e-44 152.1 0.0 1.9e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RJW71260.1 - 2.9e-41 140.2 0.0 5.2e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 RJW71260.1 - 0.00041 20.6 0.0 0.00083 19.6 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II GPR15L PF15854.5 RJW71262.1 - 0.18 12.0 0.4 24 5.3 0.1 2.8 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 HMG_box PF00505.19 RJW71263.1 - 4.3e-13 49.5 0.0 8.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Homeodomain PF00046.29 RJW71265.1 - 3.4e-21 74.8 11.1 6.2e-21 74.0 11.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW71265.1 - 0.054 13.4 1.4 0.14 12.1 1.4 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 RJW71265.1 - 0.092 13.1 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Metallophos PF00149.28 RJW71267.1 - 5.1e-40 138.2 0.1 6.7e-40 137.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RJW71267.1 - 0.00039 20.8 0.5 0.00089 19.7 0.5 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 RJW71267.1 - 0.073 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain CAP PF00188.26 RJW71268.1 - 6.5e-19 69.0 0.1 1.7e-17 64.4 0.1 2.1 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Filament PF00038.21 RJW71270.1 - 0.00031 20.4 4.4 0.014 15.0 1.2 2.2 2 0 0 2 2 2 2 Intermediate filament protein Nup88 PF10168.9 RJW71270.1 - 0.0023 15.8 0.9 0.0023 15.8 0.9 1.5 2 0 0 2 2 2 1 Nuclear pore component Takusan PF04822.13 RJW71270.1 - 0.0086 15.9 3.6 0.83 9.6 0.0 2.8 2 1 0 2 2 2 2 Takusan DUF4164 PF13747.6 RJW71270.1 - 0.05 13.9 11.1 0.69 10.2 3.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) GDPD PF03009.17 RJW71270.1 - 0.056 13.2 0.3 0.23 11.2 0.2 2.0 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Baculo_PEP_C PF04513.12 RJW71270.1 - 0.064 13.3 1.6 0.98 9.5 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Suppressor_APC PF11414.8 RJW71270.1 - 0.17 12.0 3.3 0.17 12.0 1.5 2.0 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein APG6_N PF17675.1 RJW71270.1 - 0.8 10.2 9.9 0.3 11.6 3.1 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Rep_fac-A_3 PF08661.11 RJW71271.1 - 1.2e-19 70.6 0.0 1.3e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Fucose_iso_N1 PF07881.12 RJW71271.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain MFS_1 PF07690.16 RJW71272.1 - 3e-13 49.4 44.3 4.7e-12 45.5 21.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily NUDIX PF00293.28 RJW71273.1 - 1.4e-08 34.8 0.1 2.7e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain Fz PF01392.22 RJW71274.1 - 1.8e-28 99.4 4.4 2.7e-28 98.8 4.4 1.2 1 0 0 1 1 1 1 Fz domain I-set PF07679.16 RJW71275.1 - 6.5e-139 452.4 1.7 5.6e-13 48.8 0.0 15.8 15 0 0 15 15 15 13 Immunoglobulin I-set domain fn3 PF00041.21 RJW71275.1 - 7.4e-135 439.7 21.1 1.4e-15 57.4 0.0 9.8 9 0 0 9 9 9 9 Fibronectin type III domain Ig_3 PF13927.6 RJW71275.1 - 9.4e-94 308.1 0.0 3.3e-10 40.4 0.0 14.4 13 0 0 13 13 13 13 Immunoglobulin domain ig PF00047.25 RJW71275.1 - 5.8e-48 161.0 4.9 4.2e-06 26.8 0.0 12.9 13 1 0 13 13 13 7 Immunoglobulin domain Ig_2 PF13895.6 RJW71275.1 - 3.5e-46 155.4 2.9 3.6e-07 30.4 0.0 13.4 14 0 0 14 14 13 8 Immunoglobulin domain V-set PF07686.17 RJW71275.1 - 6.4e-38 129.3 10.9 0.0022 18.2 0.0 15.7 12 4 1 13 13 13 8 Immunoglobulin V-set domain Tissue_fac PF01108.17 RJW71275.1 - 2.4e-18 65.9 0.0 0.037 13.9 0.0 9.1 9 0 0 9 9 9 4 Tissue factor Pur_ac_phosph_N PF16656.5 RJW71275.1 - 3.3e-11 43.6 11.6 0.18 12.4 0.0 8.4 8 1 0 8 8 8 2 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 RJW71275.1 - 2.4e-10 40.4 0.0 0.025 14.6 0.0 6.6 6 0 0 6 6 6 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RJW71275.1 - 1.5e-09 37.2 2.2 0.36 10.4 0.0 6.6 7 0 0 7 7 7 2 Immunoglobulin domain Receptor_2B4 PF11465.8 RJW71275.1 - 1.6e-08 34.7 4.4 5.7 7.2 0.0 9.8 10 2 1 11 11 11 1 Natural killer cell receptor 2B4 bMG6 PF17962.1 RJW71275.1 - 2.3e-07 30.9 5.7 24 5.1 0.0 10.1 10 0 0 10 10 10 0 Bacterial macroglobulin domain 6 Ig_4 PF16680.5 RJW71275.1 - 3.4e-07 30.4 12.8 0.87 9.9 0.6 7.9 7 1 0 7 7 7 2 T-cell surface glycoprotein CD3 delta chain BiPBP_C PF06832.12 RJW71275.1 - 3.7e-07 30.1 0.2 4 7.6 0.0 7.6 7 0 0 7 7 7 1 Penicillin-Binding Protein C-terminus Family Izumo-Ig PF16706.5 RJW71275.1 - 4e-07 30.0 8.2 0.091 12.8 0.1 8.1 9 0 0 9 9 9 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 RJW71275.1 - 4.4e-05 23.8 6.4 0.065 13.6 0.0 6.1 7 0 0 7 7 6 1 Immunoglobulin C1-set domain Y_Y_Y PF07495.13 RJW71275.1 - 0.00027 20.8 5.8 2.8 8.0 0.0 6.7 7 0 0 7 7 7 1 Y_Y_Y domain fn3_2 PF16893.5 RJW71275.1 - 0.0012 19.0 0.0 25 5.1 0.0 5.2 5 0 0 5 5 4 0 Fibronectin type III domain MIB_HERC2 PF06701.13 RJW71275.1 - 0.32 11.3 7.1 44 4.4 0.2 5.5 4 0 0 4 4 4 0 Mib_herc2 Hist_deacetyl PF00850.19 RJW71277.1 - 1.4e-155 517.4 0.4 5.1e-76 256.1 0.0 3.1 2 1 0 2 2 2 2 Histone deacetylase domain zf-UBP PF02148.19 RJW71277.1 - 2.9e-19 69.1 10.8 8.1e-19 67.7 10.8 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 RJW71277.1 - 0.001 18.8 1.4 0.0032 17.2 1.4 1.8 1 0 0 1 1 1 1 Variant UBP zinc finger DUF4452 PF14618.6 RJW71277.1 - 5.2 6.9 8.9 0.65 9.8 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4452) SPX PF03105.19 RJW71279.1 - 9.7 6.0 19.1 12 5.7 19.1 1.0 1 0 0 1 1 1 0 SPX domain Hist_deacetyl PF00850.19 RJW71280.1 - 1.5e-71 241.4 0.2 4.1e-70 236.7 0.2 2.7 2 1 0 2 2 2 1 Histone deacetylase domain DUF2946 PF11162.8 RJW71280.1 - 0.0059 17.3 0.2 0.021 15.5 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Pkinase PF00069.25 RJW71281.1 - 8.5e-61 205.6 0.0 7.3e-34 117.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW71281.1 - 5.7e-37 127.4 0.0 7.1e-23 81.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 RJW71281.1 - 1.9e-07 30.6 0.0 4.6e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RJW71281.1 - 4.5e-05 22.4 0.0 0.00018 20.4 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW71281.1 - 0.00011 21.7 0.0 0.043 13.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like zf-LITAF-like PF10601.9 RJW71282.1 - 3e-22 78.6 12.2 4.6e-22 78.1 12.2 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain NTP_transf_7 PF07984.12 RJW71283.1 - 9.3e-113 376.7 0.0 2.3e-82 276.8 0.1 2.1 2 0 0 2 2 2 2 Nucleotidyltransferase Cadherin_C PF01049.17 RJW71284.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Cadherin cytoplasmic region CAP PF00188.26 RJW71285.1 - 1.6e-18 67.8 0.0 1.1e-17 65.0 0.0 2.1 1 1 0 1 1 1 1 Cysteine-rich secretory protein family zf-C2H2_4 PF13894.6 RJW71286.1 - 1.1e-15 57.0 57.5 0.019 15.8 0.4 10.7 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW71286.1 - 8.5e-14 51.1 63.7 0.00057 20.2 1.3 10.3 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW71286.1 - 2.6e-10 40.2 51.5 9.6e-06 25.8 1.6 9.6 10 0 0 10 10 10 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW71286.1 - 2.6e-08 33.9 33.3 0.043 14.1 0.0 7.6 8 0 0 8 8 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RJW71286.1 - 6.4e-07 29.6 35.4 0.24 11.8 0.6 7.4 1 1 6 7 7 7 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 RJW71286.1 - 7.3e-05 23.0 27.0 0.024 15.0 0.5 6.8 7 0 0 7 7 6 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RJW71286.1 - 0.00016 21.6 3.9 0.0059 16.6 0.1 8.0 9 0 0 9 9 8 3 C2H2-type zinc finger zf-Di19 PF05605.12 RJW71286.1 - 0.0018 18.6 4.0 0.0018 18.6 4.0 5.8 4 3 2 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 RJW71286.1 - 0.0031 18.2 28.1 0.16 12.7 5.7 4.6 1 1 4 5 5 5 3 Zinc finger C2H2-type, 3 repeats Elf1 PF05129.13 RJW71286.1 - 0.023 14.8 0.6 0.023 14.8 0.6 5.5 3 2 2 5 5 5 0 Transcription elongation factor Elf1 like FOXP-CC PF16159.5 RJW71286.1 - 0.04 14.5 0.3 0.04 14.5 0.3 5.2 4 2 2 6 6 5 0 FOXP coiled-coil domain zinc_ribbon_15 PF17032.5 RJW71286.1 - 0.48 11.2 26.9 0.48 11.2 0.2 5.3 2 1 3 6 6 6 0 zinc-ribbon family zf-C2H2_9 PF16293.5 RJW71286.1 - 1.5 8.7 10.5 3.3 7.6 0.0 5.1 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 RJW71286.1 - 2 8.3 7.7 5.4 6.9 0.3 4.5 4 0 0 4 4 4 0 zinc-finger C2H2-type DUF629 PF04780.12 RJW71286.1 - 2 6.8 21.2 2.6 6.5 0.3 4.9 3 2 2 5 5 5 0 Protein of unknown function (DUF629) C1_1 PF00130.22 RJW71286.1 - 5.4 7.0 22.1 7.9 6.5 0.3 5.5 5 1 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) EGF PF00008.27 RJW71289.1 - 8.9e-20 70.7 134.7 5.8e-07 29.7 2.7 11.8 11 1 0 11 11 11 6 EGF-like domain DSL PF01414.19 RJW71289.1 - 1.2e-17 63.9 4.8 1.2e-17 63.9 4.8 7.7 5 2 3 8 8 8 1 Delta serrate ligand EGF_2 PF07974.13 RJW71289.1 - 2.3e-11 43.8 139.7 0.0023 18.3 10.3 10.9 10 0 0 10 10 10 7 EGF-like domain hEGF PF12661.7 RJW71289.1 - 8.6e-10 38.9 103.2 0.00047 20.7 6.7 11.0 10 0 0 10 10 10 6 Human growth factor-like EGF EGF_CA PF07645.15 RJW71289.1 - 0.0002 21.5 3.8 0.0002 21.5 3.8 9.7 5 2 4 9 9 9 3 Calcium-binding EGF domain P53 PF00870.18 RJW71291.1 - 3.3e-27 95.5 0.0 5.1e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 P53 DNA-binding domain Anoctamin PF04547.12 RJW71292.1 - 1.4e-146 488.9 14.4 1.8e-146 488.6 14.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 RJW71292.1 - 1.8e-67 227.4 0.0 2.6e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Claudin_2 PF13903.6 RJW71292.1 - 0.012 15.4 1.8 0.013 15.3 0.1 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Carb_bind PF10645.9 RJW71292.1 - 0.067 13.4 1.5 0.17 12.2 1.5 1.6 1 0 0 1 1 1 0 Carbohydrate binding DUF2207 PF09972.9 RJW71292.1 - 0.72 8.6 10.4 0.37 9.5 0.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Forkhead PF00250.18 RJW71294.1 - 2.1e-36 124.1 0.2 4.4e-36 123.0 0.2 1.6 1 0 0 1 1 1 1 Forkhead domain Paxillin PF03535.13 RJW71296.1 - 0.074 12.9 0.0 0.096 12.6 0.0 1.1 1 0 0 1 1 1 0 Paxillin family IPP-2 PF04979.14 RJW71297.1 - 1.8e-05 25.5 1.9 1.8e-05 25.5 1.9 1.8 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) CSN8_PSD8_EIF3K PF10075.9 RJW71298.1 - 4.5e-16 59.1 0.0 1.4e-14 54.3 0.0 2.0 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 RJW71298.1 - 0.048 14.2 0.2 0.099 13.2 0.2 1.6 1 0 0 1 1 1 0 PCI domain CRM1_C PF08767.11 RJW71300.1 - 7.3e-115 383.5 5.5 7.3e-115 383.5 5.5 2.2 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 RJW71300.1 - 3.3e-37 127.8 3.0 3.3e-37 127.8 3.0 4.9 4 1 1 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 RJW71300.1 - 6.9e-34 115.3 1.9 1.3e-33 114.5 0.7 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 RJW71300.1 - 1.2e-30 105.3 0.5 2.1e-29 101.4 0.3 2.9 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 RJW71300.1 - 1.3e-17 63.0 3.9 4.3e-17 61.3 3.9 2.0 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 RJW71300.1 - 4.8e-11 42.4 0.1 1.7e-10 40.6 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain BID PF06393.11 RJW71300.1 - 0.033 13.7 0.1 0.25 10.9 0.1 2.6 3 0 0 3 3 3 0 BH3 interacting domain (BID) RhoGEF PF00621.20 RJW71300.1 - 0.1 12.9 5.7 0.55 10.4 0.3 3.6 3 0 0 3 3 3 0 RhoGEF domain PV-1 PF06637.11 RJW71301.1 - 0.015 14.1 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Peptidase_M32 PF02074.15 RJW71301.1 - 0.082 11.7 4.4 0.084 11.6 0.2 2.6 3 0 0 3 3 3 0 Carboxypeptidase Taq (M32) metallopeptidase WH1 PF00568.23 RJW71303.1 - 1.6e-11 44.2 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 RJW71303.1 - 0.011 15.2 0.3 0.011 15.2 0.3 1.5 2 0 0 2 2 2 0 VASP tetramerisation domain DUF3551 PF12071.8 RJW71303.1 - 0.058 13.5 0.5 0.13 12.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) RVT_1 PF00078.27 RJW71306.1 - 3.4e-46 157.5 0.5 1.2e-45 155.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW71306.1 - 1.6e-11 44.1 0.0 9.2e-11 41.6 0.0 2.4 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Methyltransf_23 PF13489.6 RJW71308.1 - 4.1e-11 43.0 0.0 1e-10 41.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RJW71308.1 - 2.3e-09 37.8 0.0 7.1e-07 29.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW71308.1 - 8.1e-07 29.7 0.0 0.002 18.8 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 RJW71308.1 - 7.3e-06 26.7 0.0 0.0041 17.8 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 RJW71308.1 - 0.0001 22.1 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 RJW71308.1 - 0.0016 17.8 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 RJW71308.1 - 0.037 13.9 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_32 PF13679.6 RJW71308.1 - 0.11 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.27 RJW71314.1 - 3.6e-43 145.4 0.7 8.2e-21 73.7 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein EF-hand_7 PF13499.6 RJW71314.1 - 3.4e-13 49.9 1.2 2.2e-06 28.0 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW71314.1 - 1.5e-11 43.2 1.2 6.6e-05 22.5 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RJW71314.1 - 1.3e-09 36.9 1.4 0.0005 19.4 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 RJW71314.1 - 1.6e-09 36.8 5.5 0.00028 20.2 0.1 3.4 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 RJW71314.1 - 1.5e-06 28.0 0.2 0.033 14.0 0.1 2.8 2 1 1 3 3 3 2 EF-hand domain pair DUF2666 PF10869.8 RJW71314.1 - 2.4e-05 24.6 0.2 0.26 11.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2666) EF-hand_9 PF14658.6 RJW71314.1 - 0.0008 19.7 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 RJW71314.1 - 0.0087 16.2 1.2 0.053 13.7 0.1 2.2 2 0 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 RJW71314.1 - 0.026 14.8 0.2 6.3 7.2 0.0 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1456 PF07308.13 RJW71314.1 - 0.089 13.1 0.1 0.73 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) KNOX2 PF03791.13 RJW71316.1 - 0.07 12.6 0.4 0.24 10.9 0.4 1.9 1 0 0 1 1 1 0 KNOX2 domain IL4_i_Ig PF18258.1 RJW71318.1 - 5.6e-24 84.2 0.4 8.7e-24 83.6 0.4 1.3 1 0 0 1 1 1 1 Interleukin-4 inducing immunoglobulin-binding domain Crystall PF00030.19 RJW71318.1 - 0.0003 20.9 0.6 0.0039 17.4 0.6 2.2 1 1 0 1 1 1 1 Beta/Gamma crystallin DUF4503 PF14951.6 RJW71319.1 - 0.058 11.9 0.0 0.073 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Peptidase_C54 PF03416.19 RJW71320.1 - 8.4e-83 278.0 0.0 1e-82 277.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 RJW71320.1 - 0.061 12.8 0.1 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Peptidase family C78 Phage_int_SAM_1 PF02899.17 RJW71321.1 - 0.071 13.4 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain UCH PF00443.29 RJW71323.1 - 2.6e-43 148.4 0.0 3.8e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW71323.1 - 8e-16 58.5 0.2 1.4e-15 57.7 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RJW71323.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family TPR_19 PF14559.6 RJW71324.1 - 3.7e-13 49.8 13.6 0.0017 18.8 0.1 7.3 6 2 2 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW71324.1 - 2.2e-10 40.6 26.3 9.6e-06 25.7 1.3 5.5 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RJW71324.1 - 4.4e-06 27.1 5.4 1.9 9.5 0.0 7.6 8 2 1 9 9 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW71324.1 - 1.2e-05 25.0 4.3 0.09 12.8 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RJW71324.1 - 1.7e-05 24.9 0.1 0.087 13.0 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Coatomer_E PF04733.14 RJW71324.1 - 4.9e-05 22.9 0.3 4.9e-05 22.9 0.3 2.6 3 1 0 3 3 3 1 Coatomer epsilon subunit TPR_6 PF13174.6 RJW71324.1 - 0.0002 21.8 14.2 2 9.2 0.1 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW71324.1 - 0.0011 18.9 27.7 0.071 13.3 0.2 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW71324.1 - 0.0029 18.2 4.4 0.72 10.6 0.2 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW71324.1 - 0.0033 17.7 16.1 1.6 9.0 0.7 6.2 4 3 3 7 7 7 3 Tetratricopeptide repeat SRP_TPR_like PF17004.5 RJW71324.1 - 0.0055 16.7 16.0 0.0089 16.0 0.1 4.2 4 1 0 4 4 4 1 Putative TPR-like repeat PPR_2 PF13041.6 RJW71324.1 - 0.0089 16.2 0.7 1.7 8.9 0.0 3.7 4 1 1 5 5 4 1 PPR repeat family PPR PF01535.20 RJW71324.1 - 0.028 14.6 5.1 25 5.4 0.1 5.3 5 0 0 5 5 5 0 PPR repeat TPR_8 PF13181.6 RJW71324.1 - 0.73 10.2 17.8 2.4 8.6 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW71324.1 - 0.86 9.5 23.2 0.3 11.0 0.2 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat RasGEF PF00617.19 RJW71325.1 - 1.6e-51 175.0 4.2 3.4e-51 173.9 4.2 1.5 1 0 0 1 1 1 1 RasGEF domain Fer2_3 PF13085.6 RJW71327.1 - 8.9e-25 86.8 0.1 1.6e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Usp PF00582.26 RJW71327.1 - 1.7e-22 80.5 0.0 2.9e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family Fer2 PF00111.27 RJW71327.1 - 0.022 14.7 1.2 0.042 13.8 1.2 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain F5_F8_type_C PF00754.25 RJW71328.1 - 1.4e-10 41.4 0.0 2.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain GspL_C PF12693.7 RJW71328.1 - 0.31 10.9 1.5 13 5.6 0.1 2.3 2 0 0 2 2 2 0 GspL periplasmic domain LIM PF00412.22 RJW71329.1 - 5.2e-27 93.8 14.4 3.9e-16 59.0 1.4 2.7 3 0 0 3 3 3 2 LIM domain Homeodomain PF00046.29 RJW71329.1 - 3.6e-21 74.8 2.1 6e-21 74.0 2.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW71329.1 - 0.0014 18.5 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain C1_1 PF00130.22 RJW71329.1 - 8.9 6.3 11.4 3.3 7.7 2.7 2.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 RJW71330.1 - 0.0012 19.3 0.2 0.013 16.0 0.0 2.5 3 0 0 3 3 3 1 PH domain Trp_leader1 PF08055.11 RJW71333.1 - 0.26 11.0 3.1 0.48 10.2 3.1 1.4 1 0 0 1 1 1 0 Tryptophan leader peptide C1_1 PF00130.22 RJW71335.1 - 1.2e-06 28.3 2.7 2.8e-06 27.1 2.3 1.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGAP PF00620.27 RJW71335.1 - 1.7e-05 24.7 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain C1_2 PF03107.16 RJW71335.1 - 0.017 15.4 1.3 0.027 14.8 1.3 1.4 1 0 0 1 1 1 0 C1 domain PHD_4 PF16866.5 RJW71335.1 - 0.08 13.0 1.3 0.15 12.1 1.3 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 RJW71335.1 - 0.14 11.8 4.2 0.23 11.1 4.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 RJW71335.1 - 0.18 11.7 2.0 0.32 10.9 2.0 1.4 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 RJW71335.1 - 0.45 10.7 2.7 0.74 10.0 2.7 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger DZR PF12773.7 RJW71335.1 - 0.73 9.9 4.4 0.7 10.0 2.9 1.8 2 0 0 2 2 2 0 Double zinc ribbon PAN_1 PF00024.26 RJW71337.1 - 8.3e-06 25.7 1.3 1.8e-05 24.6 1.3 1.5 1 0 0 1 1 1 1 PAN domain C2 PF00168.30 RJW71339.1 - 1.6e-53 179.3 0.0 6.5e-23 81.0 0.0 3.4 3 0 0 3 3 3 3 C2 domain SMP_LBD PF17047.5 RJW71339.1 - 2.1e-39 134.8 0.1 3.4e-39 134.2 0.1 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 RJW71339.1 - 0.055 13.2 0.0 4.3 7.0 0.0 3.1 4 0 0 4 4 4 0 N-terminal C2 in EEIG1 and EHBP1 proteins S10_plectin PF03501.15 RJW71340.1 - 2.8e-15 56.2 0.1 1.3e-12 47.6 0.0 2.1 1 1 1 2 2 2 2 Plectin/S10 domain ArfGap PF01412.18 RJW71341.1 - 4.2e-38 130.0 0.2 8.6e-38 129.0 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RVT_1 PF00078.27 RJW71341.1 - 9e-30 103.8 0.0 1.7e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.22 RJW71341.1 - 6.3e-15 55.1 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Ras family PH PF00169.29 RJW71341.1 - 3e-06 27.7 0.1 0.13 12.8 0.0 2.8 2 0 0 2 2 2 2 PH domain Ank_2 PF12796.7 RJW71341.1 - 0.00048 20.7 0.0 0.00096 19.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PH_6 PF15406.6 RJW71341.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Roc PF08477.13 RJW71341.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ank_5 PF13857.6 RJW71341.1 - 0.11 12.9 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PH_13 PF16652.5 RJW71341.1 - 0.21 11.4 0.1 0.45 10.3 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3552 PF12072.8 RJW71342.1 - 0.0038 16.7 1.3 0.006 16.0 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF4541 PF15074.6 RJW71342.1 - 0.008 16.8 0.5 0.016 15.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4541) FAM183 PF14886.6 RJW71342.1 - 0.009 16.7 1.2 0.021 15.5 1.1 1.9 1 1 0 1 1 1 1 FAM183A and FAM183B related SIR2 PF02146.17 RJW71342.1 - 0.036 14.0 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Sir2 family EF-hand_9 PF14658.6 RJW71343.1 - 3e-07 30.7 0.0 0.00058 20.1 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RJW71343.1 - 0.00052 20.4 0.0 0.004 17.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW71343.1 - 0.0055 16.5 0.2 0.3 11.0 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain pair RRM_1 PF00076.22 RJW71346.1 - 1.2e-35 121.1 0.1 4.1e-12 45.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW71346.1 - 0.00052 20.1 0.1 1.6 8.9 0.1 3.2 2 1 0 2 2 2 2 RNA recognition motif DND1_DSRM PF14709.7 RJW71346.1 - 0.033 14.4 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 CH PF00307.31 RJW71347.1 - 4.3e-68 226.4 3.3 1.4e-20 73.5 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW71347.1 - 1.2e-05 25.1 0.2 0.23 11.3 0.0 2.9 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 RJW71347.1 - 0.00053 20.0 0.1 0.59 10.3 0.0 3.4 3 0 0 3 3 3 2 CH-like domain in sperm protein TPR_19 PF14559.6 RJW71348.1 - 1.4e-17 63.9 17.8 2.6e-05 24.6 0.3 7.5 6 3 2 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 RJW71348.1 - 1.5e-17 63.7 8.7 0.015 15.6 0.0 8.0 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 RJW71348.1 - 2e-17 61.8 24.8 0.00011 22.1 0.6 9.5 10 1 1 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 RJW71348.1 - 1.1e-14 53.5 24.1 0.0009 19.0 0.2 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW71348.1 - 1.1e-13 51.2 17.3 3.7e-06 27.1 2.7 4.5 3 2 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RJW71348.1 - 2.7e-10 40.2 12.7 0.028 15.0 0.1 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RJW71348.1 - 3e-09 36.4 23.9 0.0018 18.3 0.0 7.9 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 RJW71348.1 - 1.4e-08 34.9 10.9 12 7.1 0.0 8.4 6 3 3 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW71348.1 - 5.4e-08 32.3 23.0 0.0029 17.5 0.5 9.5 10 1 1 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 RJW71348.1 - 9e-06 26.2 10.3 0.0023 18.5 0.2 5.6 6 1 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RJW71348.1 - 0.00013 21.9 12.8 0.062 13.4 0.3 4.7 5 0 0 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 RJW71348.1 - 0.00015 21.5 11.5 0.036 13.9 0.2 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW71348.1 - 0.00095 19.3 6.1 1.9 8.7 0.0 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 RJW71348.1 - 0.0018 18.3 0.1 0.0018 18.3 0.1 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF4810 PF16068.5 RJW71348.1 - 0.0054 17.3 6.4 0.86 10.2 0.0 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4810) HrpB1_HrpK PF09613.10 RJW71348.1 - 0.028 14.1 0.1 2.2 7.9 0.0 3.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF285 PF03382.14 RJW71348.1 - 0.051 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 COG2 PF06148.11 RJW71348.1 - 0.1 12.7 1.2 5.8 7.0 0.1 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_17 PF13431.6 RJW71348.1 - 0.11 13.0 6.8 5.9 7.5 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.18 RJW71348.1 - 1.5 8.9 9.5 1.7 8.8 0.2 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain WD40 PF00400.32 RJW71351.1 - 4.2e-36 122.3 19.1 1.6e-05 25.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW71351.1 - 6.7e-11 42.3 0.0 0.058 13.7 0.1 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RJW71351.1 - 0.00096 18.6 0.0 0.029 13.7 0.0 2.6 1 1 1 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 RJW71351.1 - 0.016 13.8 0.0 0.23 9.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain TFIIB PF00382.19 RJW71352.1 - 3.2e-40 136.0 4.0 8.1e-24 83.5 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 RJW71352.1 - 3.3e-10 39.3 0.1 6.2e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RVT_1 PF00078.27 RJW71352.1 - 4.2e-05 23.2 0.0 8.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cyclin_N PF00134.23 RJW71352.1 - 5.4e-05 22.9 0.2 0.00057 19.6 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain RB_B PF01857.20 RJW71352.1 - 0.00048 20.2 0.1 0.00096 19.2 0.1 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 RJW71352.1 - 0.061 13.4 0.5 8.4 6.5 0.2 2.4 1 1 1 2 2 2 0 Cyclin, C-terminal domain CNOT11 PF10155.9 RJW71353.1 - 5.5e-41 139.6 5.7 5.6e-41 139.6 3.4 2.1 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 11 Fringe PF02434.16 RJW71354.1 - 1.6e-11 44.1 0.1 6.5e-11 42.2 0.1 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RJW71354.1 - 2e-07 31.0 0.0 5.6e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 Galactosyltransferase Pox_A14 PF05767.12 RJW71354.1 - 0.34 11.1 1.6 0.64 10.2 0.2 1.9 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 YhhN PF07947.14 RJW71355.1 - 3.2e-36 124.7 14.4 4.1e-36 124.3 14.4 1.1 1 0 0 1 1 1 1 YhhN family DUF3098 PF11297.8 RJW71355.1 - 0.057 13.0 1.3 0.28 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) MutS_V PF00488.21 RJW71356.1 - 4.4e-39 134.4 0.4 9.7e-27 94.2 0.0 3.4 3 0 0 3 3 3 3 MutS domain V MutS_III PF05192.18 RJW71356.1 - 5e-21 75.8 0.0 2.3e-20 73.6 0.0 2.1 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 RJW71356.1 - 1.1e-08 35.2 0.1 1.6e-05 25.2 0.0 2.7 2 0 0 2 2 2 2 MutS family domain IV MutS_II PF05188.17 RJW71356.1 - 2.7e-07 30.9 0.0 2.3e-06 27.9 0.0 2.4 2 1 0 2 2 2 1 MutS domain II DNA_mis_repair PF01119.19 RJW71358.1 - 0.15 11.8 0.1 0.26 10.9 0.0 1.5 1 1 1 2 2 2 0 DNA mismatch repair protein, C-terminal domain AAA_31 PF13614.6 RJW71358.1 - 0.17 11.8 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain BORA_N PF15280.6 RJW71359.1 - 7.1e-57 192.7 1.9 1.5e-56 191.6 1.3 1.8 2 0 0 2 2 2 1 Protein aurora borealis N-terminus LRRNT PF01462.18 RJW71359.1 - 0.056 13.1 0.3 0.18 11.5 0.3 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Morc6_S5 PF17942.1 RJW71360.1 - 9.7e-25 87.2 1.1 2.2e-16 60.2 0.1 2.3 2 0 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 RJW71360.1 - 4.2e-15 55.5 6.6 1.1e-14 54.1 6.6 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger DUF2870 PF11069.8 RJW71360.1 - 0.14 12.6 2.0 0.65 10.4 2.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DUF4746 PF15928.5 RJW71360.1 - 4.1 6.7 13.9 6.2 6.1 5.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Chibby PF14645.6 RJW71361.1 - 3.2e-07 30.8 2.3 1e-06 29.1 0.0 2.6 2 0 0 2 2 2 1 Chibby family zf-SAP30 PF13866.6 RJW71361.1 - 0.27 11.4 1.6 0.6 10.3 1.6 1.6 1 0 0 1 1 1 0 SAP30 zinc-finger TFIIA PF03153.13 RJW71361.1 - 5 7.0 32.4 1.6 8.7 29.5 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MIF4G PF02854.19 RJW71362.1 - 1.6e-49 168.4 8.1 2e-26 92.9 0.2 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 RJW71362.1 - 8.8e-18 65.3 2.0 8.8e-18 65.3 2.0 3.1 2 1 1 3 3 3 1 Up-frameshift suppressor 2 Synaptobrevin PF00957.21 RJW71362.1 - 0.05 13.4 0.3 0.15 11.9 0.3 1.7 1 0 0 1 1 1 0 Synaptobrevin Exo_endo_phos_2 PF14529.6 RJW71362.1 - 0.066 13.1 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase MLTR_LBD PF17765.1 RJW71362.1 - 0.21 11.7 3.6 11 6.2 0.0 3.5 4 0 0 4 4 4 0 MmyB-like transcription regulator ligand binding domain Presenilin PF01080.17 RJW71362.1 - 1.6 7.4 5.2 12 4.5 3.5 2.6 2 0 0 2 2 2 0 Presenilin BLM10_mid PF16507.5 RJW71363.1 - 9.2e-14 51.0 0.3 7.7e-09 34.7 0.1 3.2 3 0 0 3 3 3 3 Proteasome-substrate-size regulator, mid region Bromodomain PF00439.25 RJW71364.1 - 5.2e-11 42.5 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 RJW71364.1 - 0.0021 17.9 12.8 0.0021 17.9 12.8 2.4 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 RJW71364.1 - 0.0043 17.4 0.2 0.022 15.2 0.2 2.2 1 1 0 1 1 1 1 PWWP domain Ank_4 PF13637.6 RJW71367.1 - 1e-06 29.1 0.0 2.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SOCS_box PF07525.16 RJW71367.1 - 3.2e-05 24.2 0.7 6.8e-05 23.1 0.7 1.6 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 RJW71367.1 - 0.00021 21.8 0.0 0.00041 20.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW71367.1 - 0.087 13.2 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RhoGAP PF00620.27 RJW71368.1 - 5.9e-14 52.2 1.3 5.6e-06 26.3 0.1 3.4 2 2 0 2 2 2 2 RhoGAP domain CtsR_C PF17727.1 RJW71368.1 - 0.066 13.3 0.3 20 5.4 0.0 2.5 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain Ly-6_related PF06579.12 RJW71368.1 - 0.094 13.0 0.4 19 5.5 0.1 2.5 2 0 0 2 2 2 0 Caenorhabditis elegans ly-6-related protein CUB PF00431.20 RJW71369.1 - 0.00026 21.3 0.0 0.00047 20.5 0.0 1.6 1 0 0 1 1 1 1 CUB domain CUB_2 PF02408.20 RJW71369.1 - 0.013 15.2 0.2 0.029 14.1 0.0 1.5 2 0 0 2 2 2 0 CUB-like domain Oxidored_q6 PF01058.22 RJW71371.1 - 9.8e-23 80.4 0.0 1.7e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit RhoGAP PF00620.27 RJW71375.1 - 1.2e-06 28.4 0.2 5.3e-06 26.3 0.2 2.0 1 1 0 1 1 1 1 RhoGAP domain NAGidase PF07555.13 RJW71376.1 - 6.6e-61 206.2 0.0 9.3e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase RhoGEF PF00621.20 RJW71379.1 - 2.3e-24 86.6 0.0 7.8e-24 84.9 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain IQ_SEC7_PH PF16453.5 RJW71379.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 PH domain Thioredoxin PF00085.20 RJW71380.1 - 1.1e-05 25.3 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin EF-hand_7 PF13499.6 RJW71382.1 - 8.9e-14 51.7 2.8 9.3e-06 26.0 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW71382.1 - 2.9e-11 42.4 4.1 4.6e-07 29.3 0.7 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 RJW71382.1 - 1.6e-10 39.7 8.5 1e-06 27.9 1.2 3.8 4 0 0 4 4 4 3 EF hand UPF0154 PF03672.13 RJW71382.1 - 2.1e-06 27.6 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.6 RJW71382.1 - 5.8e-05 22.4 2.4 0.00043 19.7 1.3 2.7 2 0 0 2 2 2 1 EF hand FAM76 PF16046.5 RJW71382.1 - 0.00038 19.9 1.0 0.00055 19.4 1.0 1.1 1 0 0 1 1 1 1 FAM76 protein EF-hand_8 PF13833.6 RJW71382.1 - 0.00083 19.1 2.6 0.13 12.1 0.3 3.6 2 2 1 3 3 3 2 EF-hand domain pair Coilin_N PF15862.5 RJW71382.1 - 0.026 14.3 4.5 0.047 13.5 4.5 1.3 1 0 0 1 1 1 0 Coilin N-terminus EF-hand_9 PF14658.6 RJW71382.1 - 0.055 13.8 0.0 1.7 9.0 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain Sec62 PF03839.16 RJW71382.1 - 0.3 10.6 3.9 0.44 10.0 3.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S49_N PF08496.10 RJW71382.1 - 0.84 9.7 5.3 2.9 8.0 5.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MAP17 PF15807.5 RJW71382.1 - 7.9 6.7 6.5 14 6.0 6.5 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Metallophos PF00149.28 RJW71383.1 - 4.2e-36 125.4 0.3 6e-36 124.9 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 RJW71383.1 - 3.3e-29 101.0 0.1 7.7e-29 99.8 0.1 1.7 2 0 0 2 2 2 1 PPP5 TPR repeat region DUF3791 PF12668.7 RJW71383.1 - 0.005 16.8 0.5 17 5.5 0.1 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3791) TPR_9 PF13371.6 RJW71383.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat bPH_4 PF06713.11 RJW71383.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain zf-RING_4 PF14570.6 RJW71384.1 - 8 6.3 7.6 0.67 9.8 1.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Arfaptin PF06456.13 RJW71385.1 - 9.5e-44 149.7 5.5 1.2e-43 149.4 5.5 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.18 RJW71385.1 - 2.1e-06 27.6 4.8 3.3e-06 26.9 4.8 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 RJW71385.1 - 0.0022 17.2 1.6 0.0038 16.4 1.6 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking RVT_connect PF06815.13 RJW71385.1 - 0.078 13.3 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase connection domain LINES_N PF14694.6 RJW71387.1 - 1.8e-06 27.7 0.3 3.2e-06 26.9 0.3 1.5 1 0 0 1 1 1 1 Lines N-terminus RNA_pol_Rpb8 PF03870.15 RJW71388.1 - 2.5e-43 147.6 0.4 3.2e-43 147.3 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 SCO1-SenC PF02630.14 RJW71390.1 - 0.021 14.8 0.5 0.043 13.7 0.5 1.5 1 0 0 1 1 1 0 SCO1/SenC Kinesin PF00225.23 RJW71391.1 - 1.6e-95 319.9 1.4 1.6e-95 319.9 1.4 1.6 1 1 1 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW71391.1 - 1.3e-44 151.8 0.3 4.2e-44 150.1 0.1 2.0 2 0 0 2 2 2 1 Microtubule binding YabA PF06156.13 RJW71391.1 - 2.1 9.0 10.3 2.5 8.8 2.0 3.6 4 0 0 4 4 4 0 Initiation control protein YabA Kelch_1 PF01344.25 RJW71393.1 - 1.6e-66 219.6 12.5 4.3e-15 55.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RJW71393.1 - 6.7e-36 121.4 4.6 1.1e-07 31.9 0.0 6.1 3 2 3 6 6 6 5 Kelch motif BTB PF00651.31 RJW71393.1 - 1.6e-28 99.1 0.1 2.5e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 RJW71393.1 - 9.7e-28 95.1 0.2 1.9e-06 27.6 0.0 5.7 5 0 0 5 5 5 5 Kelch motif BACK PF07707.15 RJW71393.1 - 1.5e-23 82.9 0.4 3.6e-23 81.6 0.1 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 RJW71393.1 - 7.1e-21 74.0 3.0 5.2e-05 23.2 0.0 5.6 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 RJW71393.1 - 2.1e-20 72.5 5.2 2.4e-06 27.7 0.0 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW71393.1 - 4.5e-13 48.9 4.1 0.013 15.5 0.0 5.8 5 0 0 5 5 5 5 Kelch motif DUF1668 PF07893.13 RJW71393.1 - 0.041 13.2 0.1 4 6.7 0.0 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1668) Exo_endo_phos_2 PF14529.6 RJW71394.1 - 0.0063 16.3 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-H2C2_2 PF13465.6 RJW71395.1 - 7.9e-28 95.6 49.1 3.2e-06 27.3 1.2 8.9 9 0 0 9 9 8 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW71395.1 - 1.7e-24 84.4 60.1 0.0034 18.1 0.3 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW71395.1 - 2.9e-24 84.1 58.3 0.0014 18.9 0.2 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-Di19 PF05605.12 RJW71395.1 - 5.3e-11 42.6 43.6 0.00011 22.4 3.2 6.1 3 1 4 7 7 6 5 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RJW71395.1 - 3.3e-10 40.0 45.1 0.0091 16.4 1.9 8.7 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RJW71395.1 - 3.7e-05 23.6 49.9 0.022 14.8 0.2 8.7 9 0 0 9 9 8 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW71395.1 - 0.0004 20.6 56.1 0.006 16.8 0.4 8.3 9 0 0 9 9 7 4 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 RJW71395.1 - 0.0022 18.4 7.4 0.025 15.0 0.1 4.8 4 0 0 4 4 3 1 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_9 PF14369.6 RJW71395.1 - 0.007 16.6 8.6 2.6 8.4 0.1 5.3 5 0 0 5 5 4 1 zinc-ribbon zf-C2H2_3rep PF18868.1 RJW71395.1 - 0.0081 16.8 49.2 0.2 12.3 2.0 7.5 4 2 2 6 6 6 4 Zinc finger C2H2-type, 3 repeats CCDC53 PF10152.9 RJW71395.1 - 0.014 15.8 17.2 0.038 14.4 4.5 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Zn-ribbon_8 PF09723.10 RJW71395.1 - 0.077 13.1 27.8 3.5 7.8 0.1 6.0 5 2 0 5 5 5 0 Zinc ribbon domain Baculo_IE-1 PF05290.11 RJW71395.1 - 0.14 12.1 17.5 3.2 7.7 0.1 4.2 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) DUF1677 PF07911.13 RJW71395.1 - 0.88 10.0 0.0 0.88 10.0 0.0 3.5 3 1 1 4 4 3 0 Protein of unknown function (DUF1677) Ctr PF04145.15 RJW71395.1 - 0.93 10.1 8.2 6.5 7.4 0.7 2.8 2 0 0 2 2 2 0 Ctr copper transporter family zf-C2H2_8 PF15909.5 RJW71395.1 - 1.7 9.0 25.4 0.58 10.5 1.1 3.7 2 1 2 4 4 4 0 C2H2-type zinc ribbon Suf PF05843.14 RJW71395.1 - 2.1 8.3 33.2 1.3 8.9 4.1 2.5 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 RJW71395.1 - 2.3 6.9 15.6 0.35 9.6 3.9 2.2 2 0 0 2 2 2 0 Presenilin EPL1 PF10513.9 RJW71395.1 - 2.4 8.5 15.6 0.41 11.0 2.9 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like RPA43_OB PF17875.1 RJW71395.1 - 2.9 8.5 7.7 1.5 9.4 1.2 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF5327 PF17261.2 RJW71395.1 - 4.4 8.1 25.5 1.2 9.9 8.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5327) PAT1 PF09770.9 RJW71395.1 - 4.5 5.4 36.2 1.1 7.4 19.3 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Spt46 PF17734.1 RJW71395.1 - 6.4 6.5 23.5 0.19 11.5 0.6 5.0 2 1 3 5 5 5 0 Spermatogenesis-associated protein 46 Rod_C PF10493.9 RJW71396.1 - 1.1e-11 43.9 1.2 2.9e-07 29.3 0.0 3.2 2 1 1 3 3 3 3 Rough deal protein C-terminal region PEMT PF04191.13 RJW71396.1 - 0.075 13.4 0.0 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 Phospholipid methyltransferase FSA_C PF10479.9 RJW71398.1 - 5.4e-56 190.1 0.0 4e-30 104.6 0.0 5.0 5 0 0 5 5 5 4 Fragile site-associated protein C-terminus DDE_Tnp_IS1595 PF12762.7 RJW71398.1 - 0.032 14.2 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 ISXO2-like transposase domain zf-CCHC_5 PF14787.6 RJW71399.1 - 0.0086 15.8 2.6 0.0086 15.8 2.6 2.0 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 RJW71399.1 - 0.03 14.4 8.3 0.099 12.8 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 RJW71399.1 - 0.033 14.0 1.3 0.033 14.0 1.3 2.3 2 0 0 2 2 2 0 Zinc knuckle Tnp_zf-ribbon_2 PF13842.6 RJW71399.1 - 0.26 12.1 7.8 0.61 10.9 7.8 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon 60KD_IMP PF02096.20 RJW71400.1 - 2.4e-28 99.1 5.9 3.4e-28 98.6 5.9 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein RVT_1 PF00078.27 RJW71402.1 - 0.0025 17.4 0.0 0.005 16.4 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP70 PF00012.20 RJW71403.1 - 1.7e-231 769.6 9.0 2e-231 769.4 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RJW71403.1 - 1.6e-16 60.1 0.1 2.7e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 RJW71403.1 - 0.042 13.1 0.1 0.12 11.6 0.1 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HU-CCDC81_bac_2 PF18175.1 RJW71403.1 - 0.068 13.1 0.7 1.5 8.7 0.1 2.6 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 SWI-SNF_Ssr4 PF08549.10 RJW71403.1 - 4.9 5.7 7.3 4.2 5.9 4.6 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) B56 PF01603.20 RJW71405.1 - 1.1e-183 610.9 10.6 1.4e-183 610.6 10.6 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Mog1 PF04603.12 RJW71405.1 - 0.067 13.6 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Ran-interacting Mog1 protein Sec7_N PF12783.7 RJW71405.1 - 2.4 8.0 5.9 2.7 7.9 0.2 3.3 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TIP49 PF06068.13 RJW71408.1 - 3.9e-162 539.4 1.3 5.2e-162 539.0 1.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 RJW71408.1 - 2.5e-26 91.6 0.9 2.5e-26 91.6 0.9 1.9 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 RJW71408.1 - 7.7e-11 42.5 0.6 7e-07 29.7 0.1 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RJW71408.1 - 2e-06 27.6 0.6 0.0025 17.6 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RJW71408.1 - 3.2e-06 27.2 0.1 0.0011 19.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RJW71408.1 - 1.1e-05 25.7 0.2 0.08 13.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain DnaB_C PF03796.15 RJW71408.1 - 1.9e-05 24.2 0.1 4e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_19 PF13245.6 RJW71408.1 - 2.7e-05 24.5 3.9 0.0015 18.8 3.9 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RJW71408.1 - 5.2e-05 23.7 0.2 0.00044 20.7 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 RJW71408.1 - 0.00013 21.4 0.9 0.006 16.0 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 RJW71408.1 - 0.00048 19.9 0.1 0.79 9.4 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 RJW71408.1 - 0.0011 18.5 0.2 0.0028 17.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RJW71408.1 - 0.0024 18.1 0.1 0.0087 16.3 0.1 2.0 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 RJW71408.1 - 0.006 16.1 1.8 0.26 10.7 0.4 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 RJW71408.1 - 0.0069 16.1 1.4 0.27 10.9 0.5 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RJW71408.1 - 0.0075 16.1 0.2 0.017 14.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 RJW71408.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 RJW71408.1 - 0.018 15.5 0.2 0.034 14.6 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RJW71408.1 - 0.03 13.9 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 RJW71408.1 - 0.03 14.9 0.2 0.17 12.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 RJW71408.1 - 0.032 14.0 0.4 0.067 12.9 0.4 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.15 RJW71408.1 - 0.038 14.0 0.1 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 RJW71408.1 - 0.043 13.8 1.0 0.11 12.5 0.1 2.1 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RJW71408.1 - 0.044 13.9 0.3 0.11 12.7 0.3 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 RJW71408.1 - 0.062 12.5 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.14 RJW71408.1 - 0.072 13.2 0.6 4.2 7.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain (Cdc48 subfamily) Cadherin PF00028.17 RJW71409.1 - 7e-66 218.7 2.7 1.2e-14 54.5 0.1 7.7 7 3 0 7 7 7 6 Cadherin domain Cadherin_3 PF16184.5 RJW71409.1 - 2.6e-08 33.9 6.5 0.22 11.5 0.1 6.3 6 0 0 6 6 6 3 Cadherin-like Cadherin_2 PF08266.12 RJW71409.1 - 0.00057 19.7 0.1 6.5 6.7 0.0 4.5 4 1 0 4 4 4 1 Cadherin-like RET_CLD1 PF17756.1 RJW71409.1 - 0.009 16.3 0.0 3.3 8.0 0.0 3.5 3 0 0 3 3 3 1 RET Cadherin like domain 1 Cadherin_4 PF17803.1 RJW71409.1 - 0.01 16.5 12.6 0.73 10.5 0.3 6.0 6 0 0 6 6 6 1 Bacterial cadherin-like domain DUF4381 PF14316.6 RJW71409.1 - 0.068 13.4 0.9 0.16 12.2 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-C2H2 PF00096.26 RJW71411.1 - 0.0071 16.7 6.9 0.0085 16.5 3.6 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type F-box-like PF12937.7 RJW71412.1 - 2.7e-17 62.4 1.0 6.3e-17 61.2 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RJW71412.1 - 6.3e-11 41.9 0.6 6.3e-11 41.9 0.6 3.1 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 RJW71412.1 - 0.0093 16.4 9.7 2 9.0 0.1 5.9 7 0 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW71412.1 - 0.04 13.4 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat F-box_4 PF15966.5 RJW71412.1 - 0.061 13.2 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 F-box PDZ PF00595.24 RJW71413.1 - 9.8e-05 22.6 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain NinF PF05810.12 RJW71413.1 - 0.003 17.4 0.0 0.28 11.1 0.0 2.8 2 0 0 2 2 2 1 NinF protein PDZ_6 PF17820.1 RJW71413.1 - 0.0039 17.0 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain STAT_int PF02865.17 RJW71416.1 - 0.071 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 STAT protein, protein interaction domain Integrase_H2C2 PF17921.1 RJW71417.1 - 4.4e-08 33.1 0.1 6.3e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Kinesin PF00225.23 RJW71418.1 - 1.4e-25 89.9 0.0 1e-23 83.8 0.0 3.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW71418.1 - 9.1e-07 28.9 0.0 2.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding RVT_1 PF00078.27 RJW71420.1 - 2.4e-45 154.7 0.0 3.5e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cyclin_N PF00134.23 RJW71423.1 - 7.4e-08 32.2 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 RJW71423.1 - 1.6e-06 28.6 0.0 2.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin RRM_1 PF00076.22 RJW71426.1 - 4.3e-30 103.3 0.0 3.6e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RJW71426.1 - 3.3e-05 23.9 0.1 0.004 17.2 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 RJW71426.1 - 0.00011 22.0 0.0 0.023 14.5 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 RJW71426.1 - 0.0026 17.3 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_C_2 PF13410.6 RJW71427.1 - 2.2e-05 24.4 0.0 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RhoGEF PF00621.20 RJW71428.1 - 6.5e-27 94.9 2.7 6.7e-26 91.6 1.4 2.3 2 0 0 2 2 2 1 RhoGEF domain JmjC PF02373.22 RJW71429.1 - 5.5e-41 139.6 1.3 5.5e-41 139.6 1.3 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 RJW71429.1 - 3.7e-07 30.4 18.3 1.1e-06 28.9 1.5 3.4 3 0 0 3 3 3 2 C5HC2 zinc finger dUTPase PF00692.19 RJW71430.1 - 4.2e-45 152.6 0.0 6.3e-45 152.0 0.0 1.3 1 0 0 1 1 1 1 dUTPase DUF19 PF01579.18 RJW71433.1 - 0.044 13.6 5.2 0.031 14.1 1.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF19) Crisp PF08562.10 RJW71433.1 - 6.9 7.3 9.2 25 5.6 0.2 3.4 2 1 1 3 3 3 0 Crisp ARID PF01388.21 RJW71434.1 - 4.2e-17 62.6 0.0 7.2e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 RJW71434.1 - 1.3e-15 57.1 0.3 3.2e-15 55.8 0.3 1.7 1 0 0 1 1 1 1 jmjN domain Myb_DNA-binding PF00249.31 RJW71434.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Evr1_Alr PF04777.13 RJW71435.1 - 1.8e-18 66.9 0.0 4.2e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Erv1 / Alr family FAD_SOX PF18371.1 RJW71435.1 - 0.00044 20.6 0.0 0.00085 19.7 0.0 1.4 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF35_N PF12172.8 RJW71435.1 - 0.00058 19.7 0.4 0.0012 18.7 0.4 1.5 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Pox_A14 PF05767.12 RJW71435.1 - 0.028 14.6 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DPCD PF14913.6 RJW71437.1 - 1.6e-11 43.9 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 DPCD protein family Myb_DNA-bind_6 PF13921.6 RJW71439.1 - 2.1e-05 24.7 0.0 0.00026 21.2 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RJW71439.1 - 0.00022 21.3 0.0 0.00097 19.3 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RJW71439.1 - 0.2 11.7 0.0 0.52 10.4 0.0 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Glyoxalase PF00903.25 RJW71440.1 - 5.2e-09 36.4 0.0 1e-06 28.9 0.0 2.7 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RVT_1 PF00078.27 RJW71440.1 - 1.8e-08 34.2 0.0 9.4e-08 31.8 0.0 2.2 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyoxalase_4 PF13669.6 RJW71440.1 - 7e-08 32.7 0.0 3.9e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GIY-YIG PF01541.24 RJW71440.1 - 0.0031 17.7 0.1 0.0064 16.7 0.1 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Peptidase_C2 PF00648.21 RJW71442.1 - 7.9e-88 294.3 0.0 6.2e-87 291.4 0.0 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RJW71442.1 - 6.7e-23 81.5 0.0 2e-22 80.0 0.0 1.8 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_13 PF17958.1 RJW71443.1 - 9.9e-33 111.8 0.0 2.3e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 RJW71443.1 - 1.8e-18 66.7 0.3 3.3e-17 62.7 0.5 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RJW71443.1 - 2.6e-05 23.5 0.0 0.002 17.5 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 RJW71443.1 - 0.0046 16.8 0.3 0.036 14.0 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 RJW71443.1 - 0.01 15.3 0.2 0.086 12.4 0.0 2.6 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.9 RJW71443.1 - 0.11 12.8 0.3 24 5.3 0.1 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Mfa1 PF17445.2 RJW71443.1 - 4.4 7.4 6.7 0.41 10.7 0.5 2.5 2 0 0 2 2 2 0 Mating factor A1 MMS19_N PF14500.6 RJW71445.1 - 2e-52 178.4 0.8 7.4e-51 173.2 0.0 2.6 2 1 1 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II GILT PF03227.16 RJW71445.1 - 0.0078 16.5 0.5 0.12 12.6 0.6 2.3 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) HEAT_2 PF13646.6 RJW71446.1 - 0.042 14.2 0.1 0.66 10.4 0.1 2.6 2 0 0 2 2 2 0 HEAT repeats DUF3598 PF12204.8 RJW71447.1 - 0.049 13.1 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) DEAD PF00270.29 RJW71448.1 - 3.4e-25 88.8 0.0 5.7e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW71448.1 - 6.2e-23 81.3 0.0 1.1e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW71448.1 - 3.3e-05 24.0 0.0 6.8e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 RJW71448.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 RJW71448.1 - 0.028 13.6 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 RJW71448.1 - 0.043 14.1 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Flp_C PF05202.12 RJW71448.1 - 0.061 12.9 0.0 0.48 9.9 0.0 2.0 2 0 0 2 2 2 0 Recombinase Flp protein Cadherin PF00028.17 RJW71449.1 - 1.6e-171 557.3 0.0 3.1e-16 59.6 0.0 24.6 23 2 0 23 23 23 23 Cadherin domain Cadherin_2 PF08266.12 RJW71449.1 - 3.6e-11 42.8 0.0 0.42 10.5 0.0 9.9 13 0 0 13 13 13 3 Cadherin-like Cadherin_4 PF17803.1 RJW71449.1 - 0.0074 16.9 17.1 2.6 8.7 0.0 8.8 8 1 0 8 8 8 2 Bacterial cadherin-like domain Actin PF00022.19 RJW71450.1 - 3.9e-109 365.0 0.0 1.6e-108 363.0 0.0 1.8 1 1 0 1 1 1 1 Actin RVT_1 PF00078.27 RJW71450.1 - 2.8e-41 141.5 0.0 8.2e-41 139.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1702 PF08012.11 RJW71450.1 - 0.065 12.1 0.3 2 7.2 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1702) Rab15_effector PF15208.6 RJW71451.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Rab15 effector RVT_1 PF00078.27 RJW71452.1 - 4.7e-39 134.2 0.0 1.1e-38 133.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD_2 PF06733.15 RJW71452.1 - 2.5e-35 121.7 2.2 4.8e-35 120.8 2.2 1.5 1 0 0 1 1 1 1 DEAD_2 Exo_endo_phos PF03372.23 RJW71452.1 - 0.00045 19.8 0.1 0.0037 16.8 0.1 2.2 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family AAA_22 PF13401.6 RJW71452.1 - 0.0053 17.0 0.0 0.28 11.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 RJW71452.1 - 0.0063 16.5 0.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 RJW71452.1 - 0.021 14.6 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2656 PF10847.8 RJW71452.1 - 0.033 14.3 0.0 0.84 9.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2656) AAA_16 PF13191.6 RJW71452.1 - 0.041 14.3 0.7 16 5.8 0.0 4.2 4 0 0 4 4 4 0 AAA ATPase domain Borrelia_lipo_1 PF05714.11 RJW71452.1 - 0.043 13.6 0.3 0.078 12.7 0.3 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein DUF4927 PF16279.5 RJW71452.1 - 0.43 11.6 1.9 1.3 10.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4927) ORC2 PF04084.14 RJW71453.1 - 1.1e-92 310.5 0.0 1.4e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Ank_2 PF12796.7 RJW71454.1 - 7.5e-05 23.2 0.0 0.00029 21.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW71454.1 - 0.00037 20.7 0.0 0.003 17.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RJW71454.1 - 0.0011 19.5 0.0 0.018 15.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW71454.1 - 0.0059 16.9 0.0 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RJW71454.1 - 0.013 15.9 0.0 0.92 10.1 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat TylF PF05711.11 RJW71454.1 - 0.051 12.8 0.0 2 7.6 0.0 2.4 2 1 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) RNase_PH PF01138.21 RJW71455.1 - 5.4e-21 75.5 0.0 9.4e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RJW71455.1 - 1.6e-09 37.7 0.1 7.6e-09 35.5 0.1 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RVT_1 PF00078.27 RJW71455.1 - 0.058 12.9 0.1 0.2 11.1 0.1 1.8 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tyrosinase PF00264.20 RJW71457.1 - 3.5e-29 102.7 0.6 5.7e-29 102.0 0.6 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.24 RJW71457.1 - 0.12 12.5 13.3 3.6 7.8 10.7 3.4 2 1 0 2 2 2 0 Laminin EGF domain RRM_1 PF00076.22 RJW71458.1 - 6.5e-22 77.1 0.0 4.5e-16 58.4 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW71458.1 - 1.8e-05 24.7 0.0 0.0011 19.1 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif Helicase_C_2 PF13307.6 RJW71460.1 - 1.1e-28 100.6 0.0 1.2e-28 100.5 0.0 1.0 1 0 0 1 1 1 1 Helicase C-terminal domain Ribosomal_L31e PF01198.19 RJW71461.1 - 7.6e-26 90.2 0.1 1e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Spectrin PF00435.21 RJW71462.1 - 8.4e-41 138.7 23.0 2.7e-14 53.5 0.3 4.5 5 0 0 5 5 5 4 Spectrin repeat EFhand_Ca_insen PF08726.10 RJW71462.1 - 7.6e-20 70.8 0.0 3.2e-19 68.8 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 RJW71462.1 - 3.5e-09 35.6 0.0 0.00027 20.2 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RJW71462.1 - 8.9e-08 31.5 0.0 0.00039 20.1 0.0 4.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 RJW71462.1 - 8e-06 26.2 1.4 0.00022 21.6 0.0 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 RJW71462.1 - 0.00015 21.5 0.0 1.4 8.8 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain pair Sec8_exocyst PF04048.14 RJW71462.1 - 0.0073 16.2 4.3 0.79 9.6 1.7 3.0 1 1 0 2 2 2 2 Sec8 exocyst complex component specific domain EF-hand_5 PF13202.6 RJW71462.1 - 0.066 12.7 0.0 0.4 10.3 0.0 2.5 2 0 0 2 2 2 0 EF hand Erythro-docking PF09277.11 RJW71462.1 - 0.088 12.7 0.0 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Erythronolide synthase, docking BLOC1_2 PF10046.9 RJW71462.1 - 0.22 11.8 8.4 4.5 7.6 0.0 4.2 4 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hormone_recep PF00104.30 RJW71465.1 - 6.3e-16 58.6 0.1 1.8e-15 57.1 0.1 1.8 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor RNA_pol_3_Rpc31 PF11705.8 RJW71465.1 - 0.034 14.4 7.0 0.076 13.3 7.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 YL1 PF05764.13 RJW71465.1 - 0.52 10.4 6.5 1.1 9.4 6.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 RJW71465.1 - 1.1 7.4 6.0 1.6 6.9 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 RJW71465.1 - 2.8 7.0 10.6 5 6.2 10.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein WW PF00397.26 RJW71466.1 - 1.2e-06 28.5 0.3 2.2e-06 27.6 0.3 1.4 1 0 0 1 1 1 1 WW domain FAM181 PF15238.6 RJW71466.1 - 0.00097 19.1 0.3 0.0013 18.7 0.3 1.1 1 0 0 1 1 1 1 FAM181 DUF3367 PF11847.8 RJW71466.1 - 0.068 11.0 0.1 0.098 10.5 0.1 1.2 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Tyrosinase PF00264.20 RJW71467.1 - 6.9e-25 88.6 0.1 1.3e-24 87.7 0.1 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.24 RJW71467.1 - 5.3 7.3 16.9 94 3.3 0.1 3.6 2 1 0 2 2 2 0 Laminin EGF domain ATP-synt_F PF01990.17 RJW71468.1 - 3.3e-31 107.4 0.1 3.8e-31 107.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit CX9C PF16860.5 RJW71469.1 - 0.0014 18.6 9.8 0.027 14.5 0.4 2.5 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 RJW71469.1 - 0.022 14.9 0.9 0.022 14.9 0.9 2.6 2 0 0 2 2 2 0 CHCH domain LisH PF08513.11 RJW71470.1 - 0.00038 20.3 0.0 0.00074 19.4 0.0 1.5 1 0 0 1 1 1 1 LisH RXT2_N PF08595.11 RJW71470.1 - 9 6.3 16.2 0.11 12.5 5.5 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal 7TM_GPCR_Srw PF10324.9 RJW71471.1 - 4.8e-10 39.2 11.3 6.5e-10 38.8 11.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RJW71471.1 - 2.4e-07 30.4 8.2 2.4e-07 30.4 8.2 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW71471.1 - 0.0022 17.7 13.8 0.003 17.2 13.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Peptidase_A22B PF04258.13 RJW71474.1 - 1.2e-37 130.1 15.2 1.8e-37 129.4 15.2 1.3 1 0 0 1 1 1 1 Signal peptide peptidase VHL PF01847.16 RJW71475.1 - 0.06 13.3 0.0 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 VHL beta domain 7tm_1 PF00001.21 RJW71480.1 - 1.2e-69 234.6 0.0 1.6e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW71480.1 - 7.8e-12 45.1 3.5 7.8e-12 45.1 3.5 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RJW71480.1 - 1.4e-07 31.4 4.5 1.4e-07 31.4 4.5 1.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RJW71480.1 - 4.9e-07 29.8 3.2 4.9e-07 29.8 3.2 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 RJW71480.1 - 9.2e-06 25.2 1.7 1.5e-05 24.5 1.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srbc PF10316.9 RJW71480.1 - 0.057 12.9 4.8 0.1 12.1 4.8 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc DUF2897 PF11446.8 RJW71480.1 - 8.2 6.4 6.0 22 5.0 6.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) WD40 PF00400.32 RJW71482.1 - 0.16 12.9 27.4 10 7.2 0.9 9.0 7 1 0 7 7 7 0 WD domain, G-beta repeat PQQ_3 PF13570.6 RJW71482.1 - 5.6 7.6 7.1 48 4.6 0.2 4.6 5 0 0 5 5 5 0 PQQ-like domain Acetyltransf_16 PF05301.11 RJW71483.1 - 2e-25 89.6 0.3 2.2e-25 89.5 0.3 1.0 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_1 PF00583.25 RJW71483.1 - 0.00054 20.2 0.0 0.00061 20.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RJW71483.1 - 0.002 18.5 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RJW71483.1 - 0.037 14.0 0.0 0.04 13.8 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RVT_1 PF00078.27 RJW71484.1 - 2.8e-41 141.5 0.0 7.7e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW71484.1 - 5.7e-07 29.4 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PAXIP1_C PF15364.6 RJW71485.1 - 0.0009 19.6 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein Ndr PF03096.14 RJW71486.1 - 3e-07 29.4 0.0 2e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Ndr family ubiquitin PF00240.23 RJW71487.1 - 4.6e-06 26.3 0.1 0.024 14.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 RJW71487.1 - 0.0081 16.0 0.0 0.073 12.9 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like DUF2973 PF11189.8 RJW71487.1 - 0.03 14.4 0.1 1 9.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) TraX PF05857.11 RJW71487.1 - 0.035 14.2 4.1 0.057 13.5 4.1 1.2 1 0 0 1 1 1 0 TraX protein SapA PF02199.15 RJW71488.1 - 5.1e-37 125.8 56.7 1.3e-12 47.8 7.1 7.2 7 0 0 7 7 7 5 Saposin A-type domain SapB_2 PF03489.17 RJW71488.1 - 4.4e-29 100.3 14.9 2.8e-09 36.9 0.4 6.9 6 0 0 6 6 6 5 Saposin-like type B, region 2 SapB_1 PF05184.15 RJW71488.1 - 1.7e-26 91.8 30.2 1.4e-09 37.8 4.4 6.0 6 0 0 6 6 6 3 Saposin-like type B, region 1 Rootletin PF15035.6 RJW71489.1 - 0.0091 16.0 0.3 0.024 14.7 0.3 1.6 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Mpv17_PMP22 PF04117.12 RJW71490.1 - 2.7e-19 69.1 0.5 7.2e-19 67.8 0.5 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1586 PF07625.11 RJW71490.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) Cadherin PF00028.17 RJW71491.1 - 8.7e-56 186.4 3.4 1.8e-15 57.2 0.0 7.6 6 3 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 RJW71491.1 - 5.3e-12 45.4 0.3 2.5e-07 30.5 0.0 4.9 4 0 0 4 4 4 2 Cadherin-like IRS PF02174.17 RJW71492.1 - 1.1e-10 41.3 0.0 2.3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) RrnaAD PF00398.20 RJW71493.1 - 3.7e-38 131.1 0.0 1.1e-37 129.6 0.0 1.7 2 1 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RJW71493.1 - 0.18 12.5 0.0 0.37 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 RJW71494.1 - 3.5e-33 114.8 0.0 6.7e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 RJW71494.1 - 9.6e-31 106.3 0.0 7.4e-30 103.5 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 RJW71494.1 - 1.2e-30 105.6 0.0 2.4e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain RVT_1 PF00078.27 RJW71495.1 - 9.3e-45 152.8 0.0 1.6e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW71495.1 - 6.4e-07 29.2 0.0 1.8e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW71495.1 - 8.1e-07 28.8 1.1 2e-06 27.5 0.4 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PAS_9 PF13426.7 RJW71495.1 - 6.9e-05 23.0 0.0 0.012 15.8 0.0 3.0 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 RJW71495.1 - 9.6e-05 22.4 0.0 0.057 13.4 0.0 3.5 3 0 0 3 3 3 1 PAS fold PAS_2 PF08446.11 RJW71495.1 - 0.002 18.7 0.0 1.6 9.4 0.0 2.6 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 RJW71495.1 - 0.0028 17.6 1.9 0.009 16.0 1.9 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 RJW71495.1 - 0.019 15.2 0.0 1.2 9.4 0.0 3.0 2 0 0 2 2 2 0 PAS fold TM2 PF05154.16 RJW71496.1 - 6.8e-13 48.7 12.9 1.4e-12 47.7 12.9 1.5 1 0 0 1 1 1 1 TM2 domain Ndr PF03096.14 RJW71498.1 - 9.3e-41 139.4 0.0 1.5e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 RJW71498.1 - 0.0024 17.6 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Exo_endo_phos_2 PF14529.6 RJW71498.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW71498.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Abhydrolase_3 PF07859.13 RJW71498.1 - 0.02 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAXIP1_C PF15364.6 RJW71499.1 - 2.5e-11 44.0 0.0 4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein Integrase_H2C2 PF17921.1 RJW71500.1 - 5.3e-10 39.3 0.1 9.6e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Cadherin PF00028.17 RJW71500.1 - 0.0054 17.1 0.0 4.4 7.8 0.0 2.6 2 0 0 2 2 2 2 Cadherin domain DUF3149 PF11346.8 RJW71500.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) zf-H2C2 PF09337.10 RJW71500.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 H2C2 zinc finger HLH PF00010.26 RJW71502.1 - 1.3e-06 28.3 0.8 2.9e-06 27.2 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain INPP5B_PH PF16776.5 RJW71503.1 - 0.00019 21.1 0.1 0.00076 19.2 0.0 1.9 2 0 0 2 2 2 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain PAS_12 PF18095.1 RJW71503.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain F-box-like PF12937.7 RJW71504.1 - 2e-13 50.0 1.7 2.3e-13 49.8 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RJW71504.1 - 8.6e-08 31.9 0.1 2.6e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain CdhD PF03599.16 RJW71504.1 - 0.071 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit UNC-93 PF05978.16 RJW71505.1 - 3e-32 111.5 5.1 3e-32 111.5 5.1 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 RJW71505.1 - 5.6e-12 45.2 27.0 5.6e-12 45.2 27.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.27 RJW71505.1 - 0.0061 16.1 0.1 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ARPC4 PF05856.12 RJW71507.1 - 3e-76 254.7 1.2 3.9e-76 254.3 1.2 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 RJW71507.1 - 0.016 15.3 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Sm_like domain Sulfotransfer_4 PF17784.1 RJW71508.1 - 7.7e-90 300.4 0.1 7e-60 202.5 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW71508.1 - 2.6e-05 24.7 0.1 0.00042 20.8 0.0 2.7 2 1 0 2 2 2 1 Sulfotransferase family BatA PF07584.11 RJW71508.1 - 1.5 9.3 8.8 6 7.3 1.2 2.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Polyketide_cyc PF03364.20 RJW71510.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Rer1 PF03248.13 RJW71511.1 - 6.4e-65 218.1 5.2 9e-65 217.6 5.2 1.2 1 0 0 1 1 1 1 Rer1 family RVT_1 PF00078.27 RJW71511.1 - 0.049 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1980 PF09323.10 RJW71511.1 - 0.63 9.9 3.4 1 9.2 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) LIM PF00412.22 RJW71513.1 - 5.1e-07 29.8 10.1 9.4e-07 29.0 10.1 1.4 1 0 0 1 1 1 1 LIM domain DUF2318 PF10080.9 RJW71513.1 - 1.3 9.2 4.8 5.1 7.3 1.6 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) zf-C3HC4_2 PF13923.6 RJW71513.1 - 7.6 6.5 8.6 0.47 10.3 2.2 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HLH PF00010.26 RJW71514.1 - 0.0042 17.0 0.5 0.0079 16.1 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-C2H2 PF00096.26 RJW71516.1 - 8.2e-15 54.3 52.9 1.6e-05 25.1 2.4 7.8 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW71516.1 - 1.7e-13 50.4 10.8 0.00048 20.3 0.1 5.9 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RJW71516.1 - 7.1e-10 38.9 54.7 0.036 14.9 1.8 7.9 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 RJW71516.1 - 2.4e-05 24.6 16.6 0.035 14.5 0.5 5.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RJW71516.1 - 7.1e-05 23.1 21.0 0.022 15.1 2.1 6.1 3 1 1 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 RJW71516.1 - 0.0002 21.6 28.7 0.0016 18.8 0.7 8.0 8 0 0 8 8 8 1 Zinc-finger double domain zf-Di19 PF05605.12 RJW71516.1 - 0.0078 16.5 26.0 0.45 10.9 0.2 5.6 4 1 1 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 RJW71516.1 - 0.063 13.6 8.4 18 5.7 0.1 5.2 4 0 0 4 4 4 0 zinc-ribbon DUF2256 PF10013.9 RJW71516.1 - 0.25 11.5 0.1 0.25 11.5 0.1 4.9 6 0 0 6 6 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 RJW71516.1 - 0.55 10.0 26.4 1.8 8.4 0.7 5.6 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-FPG_IleRS PF06827.14 RJW71516.1 - 0.84 9.6 8.0 1.9 8.5 0.4 3.9 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-RING_7 PF02591.15 RJW71516.1 - 1.3 9.3 8.3 10 6.4 0.0 4.0 4 0 0 4 4 4 0 C4-type zinc ribbon domain ADD_ATRX PF17981.1 RJW71516.1 - 1.9 8.4 10.6 1.8 8.5 0.5 4.3 4 0 0 4 4 4 0 Cysteine Rich ADD domain FOXP-CC PF16159.5 RJW71516.1 - 4.4 8.0 7.9 7.3 7.3 0.0 4.1 3 1 1 4 4 4 0 FOXP coiled-coil domain LIM PF00412.22 RJW71516.1 - 5.8 7.2 10.4 0.23 11.7 1.0 3.2 3 0 0 3 3 3 0 LIM domain Sulfotransfer_3 PF13469.6 RJW71517.1 - 1.1e-26 94.6 0.0 2.2e-26 93.6 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RJW71517.1 - 9.5e-06 25.3 0.1 2e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase domain TPR_2 PF07719.17 RJW71518.1 - 1.1e-10 40.7 2.7 0.029 14.5 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 RJW71518.1 - 4.2e-10 39.6 3.2 0.045 14.6 0.0 5.5 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 RJW71518.1 - 5.7e-09 36.4 2.2 0.0012 19.3 0.2 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW71518.1 - 1.6e-05 25.5 0.2 0.39 11.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW71518.1 - 8.3e-05 22.5 0.6 0.56 10.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 RJW71518.1 - 0.00029 19.9 1.1 0.097 11.6 0.3 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 RJW71518.1 - 0.0027 17.0 2.9 0.0046 16.2 2.9 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 RJW71518.1 - 0.0029 17.2 0.6 6.2 6.6 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 RJW71518.1 - 0.012 15.4 1.3 1.1 9.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 RJW71518.1 - 0.033 13.2 0.1 0.048 12.7 0.1 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TOM20_plant PF06552.12 RJW71518.1 - 0.038 13.7 0.0 12 5.5 0.0 2.4 1 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_7 PF13176.6 RJW71518.1 - 0.099 12.7 0.3 24 5.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 RJW71518.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal TraC_F_IV PF11130.8 RJW71520.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Rpr2 PF04032.16 RJW71520.1 - 0.15 12.3 8.8 0.17 12.2 7.7 1.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2039 PF10217.9 RJW71520.1 - 0.98 9.8 6.3 0.47 10.8 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Ribonuclease_3 PF00636.26 RJW71521.1 - 2.3e-20 73.2 0.1 8.8e-20 71.3 0.0 2.1 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 RJW71521.1 - 4.4e-06 26.9 1.2 9.4e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 Ribonuclease-III-like Hep_core_N PF08290.11 RJW71521.1 - 0.0074 16.2 0.5 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 Hepatitis core protein, putative zinc finger LRR_4 PF12799.7 RJW71522.1 - 8e-15 54.7 15.1 0.00063 20.1 1.6 5.2 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW71522.1 - 6.9e-12 44.9 14.0 0.00028 20.6 1.6 4.4 2 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 RJW71522.1 - 0.00046 20.4 13.0 19 6.3 0.0 7.3 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 RJW71522.1 - 0.16 11.4 8.3 0.15 11.6 1.4 2.7 2 1 1 3 3 3 0 Leucine-rich repeat N_Asn_amidohyd PF14736.6 RJW71523.1 - 1.7e-36 125.8 0.0 2.2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase RFX_DNA_binding PF02257.15 RJW71524.1 - 4e-33 113.9 0.1 1.1e-32 112.4 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 RJW71524.1 - 0.11 12.9 0.1 0.57 10.7 0.1 2.1 2 0 0 2 2 2 0 Poxvirus D5 protein-like RVT_1 PF00078.27 RJW71525.1 - 3.1e-06 26.8 0.0 4.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_22 PF03901.17 RJW71526.1 - 1.1e-97 327.9 28.2 1.3e-97 327.7 28.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family 2-Hacid_dh_C PF02826.19 RJW71527.1 - 1.4e-12 47.3 0.0 9.9e-07 28.3 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UPF0160 PF03690.13 RJW71528.1 - 3e-96 322.8 0.0 4e-96 322.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Actin PF00022.19 RJW71529.1 - 6.3e-133 443.3 0.0 2.3e-132 441.5 0.0 1.7 1 1 0 1 1 1 1 Actin Helicase_C PF00271.31 RJW71530.1 - 7.8e-16 58.4 0.0 1.7e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 RJW71530.1 - 2.2e-11 43.9 0.0 7e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 RJW71530.1 - 1.2e-08 35.2 0.1 4.3e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 RJW71530.1 - 1.8e-05 24.6 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RJW71530.1 - 0.00017 21.8 0.0 0.00048 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RJW71530.1 - 0.025 14.3 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 RJW71530.1 - 0.027 13.5 0.0 0.071 12.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 RJW71530.1 - 0.15 11.4 0.0 4.9 6.4 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_23 PF13476.6 RJW71530.1 - 0.15 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 RJW71530.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 RJW71530.1 - 0.2 10.9 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HD_4 PF13328.6 RJW71530.1 - 0.21 11.3 0.4 0.67 9.7 0.0 1.9 2 0 0 2 2 2 0 HD domain Actin PF00022.19 RJW71531.1 - 7.6e-150 499.0 0.0 2.5e-149 497.3 0.0 1.7 1 1 0 1 1 1 1 Actin Ribonuclease_3 PF00636.26 RJW71532.1 - 1.9e-43 147.4 0.0 1.6e-20 73.7 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 RJW71532.1 - 8.7e-26 90.6 0.0 9.3e-16 58.1 0.1 3.4 2 1 0 2 2 2 2 Ribonuclease-III-like PAZ PF02170.22 RJW71532.1 - 0.027 14.3 0.0 0.08 12.8 0.0 1.7 2 0 0 2 2 2 0 PAZ domain Myb_DNA-binding PF00249.31 RJW71534.1 - 2.2e-09 37.4 0.1 5.6e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RJW71534.1 - 0.0026 18.0 0.0 0.0069 16.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TRAM_LAG1_CLN8 PF03798.16 RJW71535.1 - 1.6e-11 44.3 8.5 1.6e-11 44.3 8.5 1.7 2 0 0 2 2 2 1 TLC domain DUF389 PF04087.14 RJW71535.1 - 0.12 12.4 0.7 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF389) Adeno_E4_34 PF04528.13 RJW71535.1 - 0.16 11.8 0.2 0.16 11.8 0.2 2.2 3 1 0 3 3 3 0 Adenovirus early E4 34 kDa protein conserved region Vps16_C PF04840.12 RJW71536.1 - 0.0037 16.4 0.1 1.1 8.3 0.0 2.6 3 0 0 3 3 3 2 Vps16, C-terminal region HLH PF00010.26 RJW71537.1 - 0.0007 19.5 1.9 0.0016 18.3 1.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_32 PF13565.6 RJW71537.1 - 0.026 15.1 1.8 0.047 14.3 1.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain DUF3617 PF12276.8 RJW71537.1 - 0.032 14.6 0.1 0.059 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) CSTF_C PF14304.6 RJW71537.1 - 2 8.1 7.6 0.095 12.3 1.3 2.1 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal DUF4541 PF15074.6 RJW71538.1 - 1.1e-34 118.9 0.3 1.5e-34 118.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Ribosomal_L35p PF01632.19 RJW71539.1 - 1.2e-06 28.9 0.1 1.9e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 Lysyl_oxidase PF01186.17 RJW71542.1 - 1.3e-83 279.7 0.3 1.5e-83 279.5 0.3 1.1 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.18 RJW71542.1 - 0.012 16.1 0.1 0.064 13.8 0.0 2.3 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain CARDB PF07705.11 RJW71542.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 CARDB p25-alpha PF05517.12 RJW71544.1 - 2.4e-44 151.3 5.2 2.7e-44 151.1 5.2 1.0 1 0 0 1 1 1 1 p25-alpha NYD-SP28 PF14772.6 RJW71545.1 - 4.9e-28 97.2 10.4 4.9e-28 97.2 10.4 6.3 5 1 1 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 RJW71545.1 - 4.5e-22 77.9 3.1 4.5e-22 77.9 3.1 4.3 3 2 1 4 4 4 1 Sperm tail C-terminal domain Phage_antitermQ PF06530.12 RJW71545.1 - 0.082 12.8 0.0 0.45 10.4 0.0 2.3 1 0 0 1 1 1 0 Phage antitermination protein Q Baculo_PEP_C PF04513.12 RJW71545.1 - 0.17 11.9 17.5 1.1 9.3 3.0 4.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TetR_C_24 PF17932.1 RJW71545.1 - 4.6 7.5 6.3 5 7.4 0.6 3.4 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SMK-1 PF04802.15 RJW71546.1 - 1.7e-57 194.3 5.1 1.7e-57 194.3 5.1 1.7 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 RSV_NS2 PF03113.14 RJW71546.1 - 0.12 12.4 0.7 0.27 11.3 0.7 1.5 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 SPRY PF00622.28 RJW71548.1 - 1.5e-13 50.9 0.0 3.2e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.24 RJW71548.1 - 2e-08 34.3 5.2 2e-08 34.3 5.2 4.4 4 1 0 4 4 4 1 B-box zinc finger fn3 PF00041.21 RJW71548.1 - 1.6e-05 25.2 0.0 4.4e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain zf-RING_UBOX PF13445.6 RJW71548.1 - 0.00015 21.7 4.8 0.00015 21.7 4.8 3.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RJW71548.1 - 0.00048 20.2 7.7 0.00048 20.2 7.7 4.1 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 RJW71548.1 - 0.0027 17.6 4.3 0.0027 17.6 4.3 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW71548.1 - 0.0043 16.9 4.4 0.0043 16.9 4.4 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW71548.1 - 0.0079 16.1 2.7 0.0079 16.1 2.7 4.4 4 0 0 4 4 4 1 zinc-RING finger domain DUF3053 PF11254.8 RJW71548.1 - 0.028 14.0 0.4 0.048 13.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Noelin-1 PF12308.8 RJW71548.1 - 0.68 10.0 3.0 1.1 9.2 2.2 1.8 1 1 0 1 1 1 0 Neurogenesis glycoprotein Trm112p PF03966.16 RJW71548.1 - 0.69 10.5 2.9 22 5.7 0.0 3.7 3 0 0 3 3 3 0 Trm112p-like protein Cortex-I_coil PF09304.10 RJW71548.1 - 1.7 8.9 7.6 0.7 10.1 5.1 1.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil Pkinase PF00069.25 RJW71549.1 - 8.7e-68 228.5 0.0 2.1e-67 227.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 RJW71549.1 - 1.4e-32 111.6 0.0 2.7e-15 56.2 0.0 2.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RJW71549.1 - 2.1e-31 109.2 0.0 3.6e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW71549.1 - 0.0046 16.3 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RJW71549.1 - 0.0073 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Glyco_transf_8 PF01501.20 RJW71550.1 - 2e-16 60.3 1.1 4.4e-16 59.2 1.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Lipoxygenase PF00305.19 RJW71551.1 - 4.9e-34 117.8 0.2 6.6e-33 114.1 0.3 2.1 2 0 0 2 2 2 1 Lipoxygenase PLAT PF01477.23 RJW71551.1 - 1.2e-10 42.0 0.1 2.2e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain DUF1414 PF07208.11 RJW71551.1 - 0.071 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) ChiC PF06483.11 RJW71551.1 - 0.08 12.9 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Chitinase C HLH PF00010.26 RJW71552.1 - 3e-06 27.1 1.3 9.8e-06 25.4 1.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4794 PF16042.5 RJW71552.1 - 4.8 8.2 7.8 2.8 9.0 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4794) RVT_1 PF00078.27 RJW71555.1 - 0.00074 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_Zc3h12a PF11977.8 RJW71556.1 - 0.0011 18.7 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 2 Zc3h12a-like Ribonuclease NYN domain UPF0697 PF15117.6 RJW71556.1 - 0.0058 16.7 0.0 4.9 7.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0697 DUF1794 PF08768.11 RJW71556.1 - 0.015 15.2 0.2 5.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1794) End_N_terminal PF12218.8 RJW71556.1 - 0.03 14.0 0.9 8.8 6.1 0.2 2.7 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase DUF5408 PF17402.2 RJW71556.1 - 0.38 10.7 1.8 23 4.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5408) DUF4632 PF15451.6 RJW71556.1 - 0.42 10.7 6.2 9 6.4 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) CENP-B_dimeris PF09026.10 RJW71556.1 - 6.6 7.2 12.0 13 6.3 2.2 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SepSecS PF05889.13 RJW71557.1 - 1.3e-100 336.8 0.0 8.1e-44 149.9 0.0 3.1 3 0 0 3 3 3 3 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Peptidase_S8 PF00082.22 RJW71558.1 - 2.9e-59 200.8 0.1 5.6e-59 199.8 0.1 1.5 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 RJW71558.1 - 1.5e-22 80.0 0.0 3e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Tripeptidyl peptidase II PPP4R2 PF09184.11 RJW71559.1 - 1.3e-34 120.1 1.8 1.3e-34 120.1 1.8 2.7 2 1 0 2 2 2 1 PPP4R2 RRM_1 PF00076.22 RJW71560.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW71560.1 - 0.016 15.3 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif RVT_1 PF00078.27 RJW71561.1 - 1.4e-45 155.5 0.0 2.2e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UQ_con PF00179.26 RJW71561.1 - 0.00019 21.1 0.1 0.00045 19.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF5436 PF17504.2 RJW71562.1 - 0.063 13.6 0.8 0.1 12.9 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5436) TGT PF01702.18 RJW71563.1 - 9.9e-131 436.0 0.0 1.2e-130 435.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase HLH PF00010.26 RJW71564.1 - 4.5e-06 26.5 1.7 1.1e-05 25.3 1.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NYD-SP28_assoc PF14775.6 RJW71564.1 - 0.23 11.6 1.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain EF-hand_7 PF13499.6 RJW71566.1 - 2.4e-19 69.5 5.9 2.3e-07 31.2 0.1 4.3 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 RJW71566.1 - 3.8e-15 55.5 1.5 3.6e-06 26.7 0.1 5.4 5 1 1 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 RJW71566.1 - 2.1e-14 51.9 2.6 9.7e-07 27.9 0.2 5.2 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 RJW71566.1 - 1.3e-12 46.5 5.7 0.00028 20.6 0.2 6.2 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 RJW71566.1 - 5.8e-09 35.0 5.0 9.9e-06 24.8 0.1 4.3 5 0 0 5 5 5 2 EF hand GlnD_UR_UTase PF08335.11 RJW71566.1 - 0.00063 19.9 0.1 0.029 14.4 0.0 2.4 2 0 0 2 2 2 1 GlnD PII-uridylyltransferase SPARC_Ca_bdg PF10591.9 RJW71566.1 - 0.00091 19.5 1.1 1.4 9.3 0.1 3.5 2 1 1 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region CtaG_Cox11 PF04442.14 RJW71568.1 - 1.3e-62 210.4 1.1 1.5e-62 210.1 1.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 RVT_1 PF00078.27 RJW71569.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spc7 PF08317.11 RJW71569.1 - 0.32 9.8 5.7 0.52 9.1 5.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.12 RJW71569.1 - 5 7.6 7.2 12 6.4 7.2 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Bromodomain PF00439.25 RJW71570.1 - 2.8e-27 94.6 0.0 6.2e-13 48.6 0.1 2.5 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.32 RJW71570.1 - 2.9e-05 24.7 2.1 2.2 9.3 0.0 4.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Auxin_resp PF06507.13 RJW71570.1 - 0.025 14.8 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 Auxin response factor Myelin_PLP PF01275.19 RJW71572.1 - 2.6e-09 37.3 9.3 7.7e-07 29.2 5.1 2.2 2 0 0 2 2 2 2 Myelin proteolipid protein (PLP or lipophilin) DUF3206 PF11472.8 RJW71572.1 - 0.058 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) zf-RING_2 PF13639.6 RJW71573.1 - 7.4e-14 51.8 7.8 7.4e-14 51.8 7.8 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 RJW71573.1 - 7.5e-11 41.6 3.3 1.4e-10 40.7 3.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RJW71573.1 - 3.6e-09 36.3 7.4 7.3e-09 35.4 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW71573.1 - 5e-09 35.9 6.8 1.1e-08 34.8 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW71573.1 - 6.7e-08 32.4 6.8 1.4e-07 31.3 6.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RJW71573.1 - 2.9e-07 30.4 3.8 6.4e-07 29.3 3.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 RJW71573.1 - 5e-07 29.9 8.3 1.9e-06 28.0 8.3 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RJW71573.1 - 1e-05 25.3 4.1 2e-05 24.3 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RJW71573.1 - 0.00023 20.9 4.1 0.00051 19.9 4.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RJW71573.1 - 0.00056 19.5 2.7 0.0015 18.1 2.7 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RJW71573.1 - 0.0077 16.3 1.2 0.019 15.0 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Atracotoxin PF05353.11 RJW71573.1 - 0.034 14.2 0.6 0.078 13.0 0.6 1.5 1 0 0 1 1 1 0 Delta Atracotoxin zf-C3HC4_4 PF15227.6 RJW71573.1 - 0.064 13.4 5.0 0.37 11.0 5.1 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 RJW71573.1 - 0.2 11.5 5.3 0.37 10.6 5.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 RJW71573.1 - 1.1 9.4 9.4 0.72 10.1 5.8 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 RJW71573.1 - 3.4 7.6 5.8 7.5 6.5 5.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 RJW71573.1 - 4 7.8 12.1 0.72 10.2 6.3 2.5 2 1 0 2 2 2 0 RING-like domain RINGv PF12906.7 RJW71573.1 - 5.9 7.1 12.4 0.36 11.0 6.6 2.0 2 0 0 2 2 2 0 RING-variant domain Actin PF00022.19 RJW71575.1 - 7.6e-150 499.0 0.0 2.5e-149 497.3 0.0 1.7 1 1 0 1 1 1 1 Actin 7tm_1 PF00001.21 RJW71577.1 - 1.4e-67 227.8 0.5 2e-67 227.3 0.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW71577.1 - 1.1e-10 41.4 10.1 2.4e-08 33.7 7.4 2.6 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RJW71577.1 - 1.6e-06 27.9 7.4 4.9e-06 26.4 7.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RJW71577.1 - 0.0044 16.8 1.9 0.029 14.1 1.5 2.1 2 0 0 2 2 2 1 Olfactory receptor INT_SG_DDX_CT_C PF15300.6 RJW71578.1 - 6.2e-17 61.1 0.0 1.4e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VWA_2 PF13519.6 RJW71578.1 - 3.4e-12 47.0 0.0 7.5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RJW71578.1 - 0.0037 17.5 0.0 0.0068 16.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 RJW71578.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain UPF0160 PF03690.13 RJW71579.1 - 3.9e-125 417.7 0.0 4.4e-125 417.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) FAM92 PF06730.11 RJW71580.1 - 1e-46 159.1 8.1 1.6e-46 158.5 8.1 1.2 1 0 0 1 1 1 1 FAM92 protein DUF2767 PF10965.8 RJW71580.1 - 0.0018 18.2 0.0 0.006 16.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2767) DNA_repr_REX1B PF14966.6 RJW71580.1 - 0.025 15.2 2.3 0.87 10.3 0.1 3.1 3 1 1 4 4 4 0 DNA repair REX1-B BUD22 PF09073.10 RJW71580.1 - 0.16 11.3 19.5 0.24 10.7 19.5 1.3 1 0 0 1 1 1 0 BUD22 Sld5 PF05916.11 RJW71580.1 - 0.2 12.2 6.0 0.24 11.8 3.1 2.6 1 1 1 2 2 2 0 GINS complex protein YL1 PF05764.13 RJW71580.1 - 4 7.5 27.9 4.9 7.2 15.7 2.3 2 0 0 2 2 2 0 YL1 nuclear protein DUF2053 PF09767.9 RJW71581.1 - 1.1e-36 126.4 3.6 1.6e-36 125.9 3.6 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) Snf7 PF03357.21 RJW71582.1 - 7.9e-19 67.9 6.3 1.3e-18 67.2 6.3 1.3 1 0 0 1 1 1 1 Snf7 RVT_1 PF00078.27 RJW71582.1 - 3.7e-05 23.4 0.0 0.00016 21.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ESCRT-II PF05871.12 RJW71582.1 - 0.00063 20.0 0.2 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 ESCRT-II complex subunit Spectrin PF00435.21 RJW71582.1 - 0.053 14.0 6.3 0.094 13.2 5.5 1.9 1 1 0 1 1 1 0 Spectrin repeat HSP20 PF00011.21 RJW71583.1 - 8e-24 83.7 0.0 2.1e-14 53.5 0.1 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RJW71583.1 - 5.2e-05 22.7 0.0 0.00026 20.5 0.0 2.1 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Vac_Fusion PF02346.16 RJW71583.1 - 0.077 12.6 0.1 0.27 10.9 0.1 1.9 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 BB_PF PF18063.1 RJW71583.1 - 0.71 9.4 3.2 1.5 8.4 3.2 1.5 1 0 0 1 1 1 0 Beta barrel Pore-forming domain 7tm_1 PF00001.21 RJW71585.1 - 7.8e-05 22.1 0.0 0.00013 21.4 0.0 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) UPF0020 PF01170.18 RJW71587.1 - 4.3e-06 26.5 0.1 0.0055 16.4 0.1 2.8 3 0 0 3 3 3 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 RJW71587.1 - 0.017 14.8 0.0 1.3 8.6 0.0 2.8 2 1 0 2 2 2 0 DNA methylase Mito_carr PF00153.27 RJW71589.1 - 2.8e-55 184.2 0.1 1.5e-17 63.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 RJW71590.1 - 3.8e-47 158.0 0.0 2.5e-20 72.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW71590.1 - 6.5e-09 35.8 0.2 0.0032 17.6 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 RJW71590.1 - 0.0067 16.3 0.0 3.3 7.7 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF1513 PF07433.11 RJW71590.1 - 0.062 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) PGPGW PF09656.10 RJW71590.1 - 0.11 12.0 0.3 0.24 10.9 0.3 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) NEMO PF11577.8 RJW71592.1 - 0.00078 19.4 0.0 0.0026 17.8 0.0 1.7 2 0 0 2 2 2 1 NF-kappa-B essential modulator NEMO PAXNEB PF05625.11 RJW71593.1 - 0.0064 15.7 0.1 0.077 12.1 0.0 2.6 3 0 0 3 3 3 1 PAXNEB protein Ion_trans PF00520.31 RJW71597.1 - 6.6e-39 133.6 15.7 9.6e-39 133.1 15.7 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RJW71597.1 - 9.5e-25 86.8 0.0 2.4e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RJW71597.1 - 3.8e-12 46.0 8.3 3.8e-12 46.0 8.3 2.8 3 0 0 3 3 3 1 Ion channel Shal-type PF11601.8 RJW71597.1 - 4e-10 39.1 4.3 8.7e-10 38.0 4.3 1.5 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal BTB_3 PF16017.5 RJW71597.1 - 1.1e-06 28.7 0.1 4.3e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain PKD_channel PF08016.12 RJW71597.1 - 0.8 8.3 11.7 1.7 7.2 11.7 1.7 1 1 0 1 1 1 0 Polycystin cation channel Glypican PF01153.19 RJW71598.1 - 6.6e-31 107.8 6.3 8.7e-21 74.4 0.1 2.0 2 0 0 2 2 2 2 Glypican DUF1474 PF07342.11 RJW71598.1 - 0.039 14.5 0.4 0.075 13.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) DUF667 PF05018.13 RJW71601.1 - 8.3e-42 143.0 0.3 9e-42 142.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Copine PF07002.16 RJW71602.1 - 2.7e-65 219.9 0.0 4.5e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 RJW71602.1 - 5.6e-25 87.6 0.0 4.6e-12 46.1 0.1 2.5 3 0 0 3 3 3 2 C2 domain vWA-TerF-like PF10138.9 RJW71602.1 - 1.4e-05 25.4 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Marek_A PF02124.15 RJW71603.1 - 0.034 14.0 0.0 0.069 13.0 0.0 1.4 1 1 0 1 1 1 0 Marek's disease glycoprotein A Spb1_C PF07780.12 RJW71605.1 - 1.9e-36 125.7 22.2 1.9e-36 125.7 22.2 3.3 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 RJW71605.1 - 1.6e-16 60.6 15.5 1.6e-16 60.6 15.5 4.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) KilA-N PF04383.13 RJW71605.1 - 3.1 7.7 4.6 0.87 9.4 0.8 2.0 2 0 0 2 2 2 0 KilA-N domain Peptidase_M41 PF01434.18 RJW71605.1 - 6 6.7 11.0 0.24 11.2 4.5 2.0 2 0 0 2 2 2 0 Peptidase family M41 RNA_pol_Rpb6 PF01192.22 RJW71606.1 - 5.4e-17 61.5 0.2 9.1e-17 60.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Fcf1 PF04900.12 RJW71608.1 - 2.1e-17 63.3 0.0 4.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Fcf1 SNF2_N PF00176.23 RJW71609.1 - 5.9e-67 225.9 0.9 5.9e-67 225.9 0.9 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW71609.1 - 2.2e-19 69.8 0.0 6.2e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 RJW71609.1 - 3.5e-09 36.8 6.7 5.1e-09 36.3 4.2 2.6 1 1 1 2 2 2 1 HSA FGF PF00167.18 RJW71610.1 - 0.055 13.6 0.1 0.97 9.6 0.0 2.3 2 0 0 2 2 2 0 Fibroblast growth factor Amidase PF01425.21 RJW71611.1 - 1.9e-94 317.2 0.0 4.3e-94 316.0 0.0 1.5 1 1 0 1 1 1 1 Amidase CENP-L PF13092.6 RJW71611.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 adh_short PF00106.25 RJW71612.1 - 5.7e-25 87.9 0.0 1.2e-17 64.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RJW71612.1 - 1.3e-15 57.6 0.0 7.8e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW71612.1 - 0.004 17.1 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 KR domain 7tm_1 PF00001.21 RJW71614.1 - 1.6e-16 60.4 1.4 2.1e-16 60.0 1.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW71614.1 - 0.00076 19.2 5.7 0.004 16.8 5.7 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx RVT_1 PF00078.27 RJW71616.1 - 1.6e-26 93.3 0.0 2.6e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 RJW71616.1 - 6.9e-22 77.3 14.0 0.0016 19.3 0.0 8.4 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW71616.1 - 1.9e-12 47.3 0.2 0.011 16.0 0.0 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW71616.1 - 8e-05 22.6 0.3 0.19 11.6 0.0 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 RJW71616.1 - 0.0075 16.0 0.2 19 4.9 0.0 3.3 2 1 0 3 3 3 1 TUP1-like enhancer of split Ge1_WD40 PF16529.5 RJW71616.1 - 0.0078 15.2 0.2 7 5.5 0.1 3.2 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RJW71616.1 - 0.041 13.2 0.0 0.54 9.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Nbas_N PF15492.6 RJW71616.1 - 0.081 12.2 0.0 2.8 7.2 0.0 2.9 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal CSD PF00313.22 RJW71617.1 - 4.1e-26 90.6 0.5 8.3e-26 89.6 0.5 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 RJW71617.1 - 0.093 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain DUF930 PF06059.12 RJW71621.1 - 0.15 12.7 0.2 0.3 11.7 0.1 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF930) DUF3219 PF11514.8 RJW71622.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) V-set PF07686.17 RJW71624.1 - 0.77 10.0 4.4 33 4.7 0.0 4.0 4 0 0 4 4 4 0 Immunoglobulin V-set domain zf-C3HC4_2 PF13923.6 RJW71625.1 - 1.2e-07 31.5 11.2 3.1e-07 30.1 11.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW71625.1 - 4.3e-07 29.7 7.3 1e-06 28.5 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW71625.1 - 1e-06 28.6 9.1 7.7e-06 25.8 9.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 RJW71625.1 - 2.7e-06 27.6 10.6 2.7e-06 27.6 10.6 2.3 2 0 0 2 2 2 1 Ring finger domain LON_substr_bdg PF02190.16 RJW71625.1 - 5.9e-06 26.3 0.0 9.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4 PF00097.25 RJW71625.1 - 9.4e-06 25.4 9.6 2.5e-05 24.0 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW71625.1 - 3.5e-05 23.7 8.8 9.5e-05 22.3 8.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 RJW71625.1 - 4.2e-05 23.6 6.2 9e-05 22.5 6.2 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 RJW71625.1 - 0.00011 22.3 12.7 0.00033 20.7 12.7 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RJW71625.1 - 0.00013 22.2 5.7 0.00064 19.9 4.7 2.7 3 0 0 3 3 3 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RJW71625.1 - 0.00053 19.8 9.4 0.0017 18.2 9.4 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RJW71625.1 - 0.0048 16.7 5.2 0.014 15.2 5.2 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain U-box PF04564.15 RJW71625.1 - 0.0075 16.4 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 U-box domain DUF1272 PF06906.11 RJW71625.1 - 0.025 14.7 4.0 0.064 13.4 4.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prim_Zn_Ribbon PF08273.12 RJW71625.1 - 5.9 7.3 8.6 13 6.2 0.6 3.1 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase RRM_5 PF13893.6 RJW71628.1 - 1.9e-36 124.4 0.4 1e-28 99.4 0.1 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RJW71628.1 - 5.8e-28 96.5 0.2 5.3e-07 29.4 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prefoldin_2 PF01920.20 RJW71628.1 - 1.5e-10 40.9 0.1 1.5e-10 40.9 0.1 2.0 2 0 0 2 2 2 1 Prefoldin subunit RRM_occluded PF16842.5 RJW71628.1 - 0.00036 20.3 0.4 15 5.5 0.0 4.5 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 RJW71628.1 - 0.0076 16.4 0.0 9.3 6.4 0.0 3.4 2 0 0 2 2 2 2 RNA recognition motif Stork_head PF10264.9 RJW71630.1 - 8e-26 90.0 0.1 1.5e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain Peptidase_S11 PF00768.20 RJW71634.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Cullin PF00888.22 RJW71635.1 - 8.6e-137 457.4 12.1 1.2e-136 456.9 12.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RJW71635.1 - 2.2e-20 72.4 1.4 7.4e-20 70.8 1.4 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain IFT81_CH PF18383.1 RJW71635.1 - 0.13 12.5 4.8 0.16 12.2 2.3 2.3 2 0 0 2 2 2 0 Intraflagellar transport 81 calponin homology domain Pkinase PF00069.25 RJW71636.1 - 2.3e-63 214.1 0.0 4.2e-63 213.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW71636.1 - 4.1e-37 127.9 0.0 6.8e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW71636.1 - 2.9e-11 43.2 0.0 5.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RJW71636.1 - 2.5e-05 23.7 0.0 7.5e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RJW71636.1 - 0.0024 17.5 0.1 0.0049 16.5 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RJW71636.1 - 0.0053 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family PCO_ADO PF07847.12 RJW71637.1 - 1.6e-45 155.0 0.0 2.5e-41 141.3 0.0 2.1 2 0 0 2 2 2 2 PCO_ADO zf-RING_2 PF13639.6 RJW71638.1 - 1.1e-09 38.4 9.6 1.9e-09 37.7 9.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RJW71638.1 - 1.8e-07 30.9 5.4 3.1e-07 30.1 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW71638.1 - 5e-07 29.4 6.3 8.7e-07 28.7 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RJW71638.1 - 2.2e-06 27.8 9.2 6.2e-06 26.4 9.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain CUE PF02845.16 RJW71638.1 - 9.3e-06 25.2 0.0 2.6e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 CUE domain zf-C3HC4_3 PF13920.6 RJW71638.1 - 5.8e-05 22.9 3.1 9.1e-05 22.2 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RJW71638.1 - 0.0004 20.4 2.0 0.00086 19.3 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 RJW71638.1 - 0.00064 19.6 4.0 0.001 19.0 4.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RJW71638.1 - 0.0011 18.9 3.2 0.0022 18.0 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 RJW71638.1 - 0.0061 16.3 2.4 0.013 15.2 2.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 RJW71638.1 - 0.012 15.5 4.1 0.021 14.7 4.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RJW71638.1 - 0.21 11.4 5.5 0.054 13.3 1.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 RJW71638.1 - 0.35 10.5 5.2 0.7 9.6 5.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RJW71638.1 - 0.48 10.6 3.6 1.2 9.4 3.6 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain TMEM238 PF15125.6 RJW71638.1 - 1.5 9.0 6.3 1.7 8.9 3.8 2.4 2 0 0 2 2 2 0 TMEM238 protein family zf-RING-like PF08746.11 RJW71638.1 - 5.6 7.4 5.6 10 6.5 5.6 1.4 1 0 0 1 1 1 0 RING-like domain Mob1_phocein PF03637.17 RJW71639.1 - 6.1e-26 91.4 0.7 4.3e-25 88.7 0.7 2.0 1 1 0 1 1 1 1 Mob1/phocein family RT_RNaseH PF17917.1 RJW71640.1 - 1.8e-35 121.4 0.0 3.7e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW71640.1 - 1.1e-30 105.6 0.0 2.1e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW71640.1 - 3.3e-25 88.9 0.0 8.2e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RJW71640.1 - 7.4e-24 84.2 0.0 1.8e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW71640.1 - 3.8e-18 65.3 0.9 8.3e-18 64.3 0.9 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain fn3 PF00041.21 RJW71640.1 - 1.6e-13 50.8 5.0 0.026 14.9 0.2 5.8 5 0 0 5 5 5 4 Fibronectin type III domain zf-CCHC PF00098.23 RJW71640.1 - 0.00011 22.1 3.1 0.00032 20.7 3.1 1.9 1 0 0 1 1 1 1 Zinc knuckle Pur_ac_phosph_N PF16656.5 RJW71640.1 - 0.00012 22.6 8.6 0.053 14.1 1.7 4.0 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain zf-H2C2 PF09337.10 RJW71640.1 - 0.00049 20.3 0.3 0.0014 18.8 0.3 1.9 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 RJW71640.1 - 0.00065 19.4 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 RJW71640.1 - 0.025 14.6 0.6 0.076 13.0 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle PhoD_N PF16655.5 RJW71640.1 - 0.3 11.7 1.2 25 5.5 0.0 3.1 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain BST2 PF16716.5 RJW71640.1 - 4.2 8.0 5.4 3.1 8.5 1.4 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Erv26 PF04148.13 RJW71641.1 - 2.2e-33 115.8 16.4 1e-32 113.7 16.4 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF4491 PF14898.6 RJW71641.1 - 1.7 9.2 7.1 0.31 11.5 3.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Peptidase_M50 PF02163.22 RJW71645.1 - 2.1e-21 76.4 0.0 1.2e-20 73.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M50 Peptidase_U4 PF03419.13 RJW71645.1 - 7 5.8 13.7 1.8 7.8 3.7 2.3 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Methyltr_RsmB-F PF01189.17 RJW71646.1 - 1.6e-25 90.0 0.0 2.9e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ribosomal_L9_N PF01281.19 RJW71646.1 - 2.6e-10 39.7 0.0 5.1e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain FtsJ PF01728.19 RJW71646.1 - 0.00044 20.4 0.0 0.00081 19.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 RJW71646.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_L28e PF01778.17 RJW71647.1 - 0.15 12.8 0.6 0.21 12.3 0.6 1.3 1 1 0 1 1 1 0 Ribosomal L28e protein family fn3 PF00041.21 RJW71648.1 - 2.9e-05 24.3 2.0 0.16 12.3 0.0 3.7 3 1 0 3 3 3 2 Fibronectin type III domain EDS1_EP PF18117.1 RJW71648.1 - 0.12 12.8 0.1 2.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain PB1 PF00564.24 RJW71649.1 - 1.6e-09 37.6 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.24 RJW71649.1 - 3.1e-07 30.6 0.0 5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW71649.1 - 2e-06 27.5 0.1 4.1e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain TPH PF13868.6 RJW71650.1 - 0.0053 15.3 10.3 0.0053 15.3 10.3 6.2 6 1 1 7 7 7 3 Trichohyalin-plectin-homology domain YvrJ PF12841.7 RJW71650.1 - 0.21 11.1 0.4 0.49 10.0 0.4 1.7 1 0 0 1 1 1 0 YvrJ protein family Matrilin_ccoil PF10393.9 RJW71650.1 - 1.9 8.4 5.2 17 5.3 0.2 3.3 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Tox-REase-9 PF15650.6 RJW71651.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 RT_RNaseH_2 PF17919.1 RJW71652.1 - 5.2e-08 32.8 0.0 8.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW71652.1 - 3.4e-06 27.3 0.0 5.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase fn3 PF00041.21 RJW71653.1 - 0.00011 22.4 0.3 0.00056 20.2 0.1 2.3 3 0 0 3 3 3 1 Fibronectin type III domain POT1PC PF16686.5 RJW71655.1 - 3.7e-19 69.1 0.0 6.5e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 RJW71655.1 - 1.1e-06 28.6 0.0 6.5e-05 22.8 0.0 2.8 3 1 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 zinc_ribbon_10 PF10058.9 RJW71655.1 - 0.012 15.3 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein HEAT_2 PF13646.6 RJW71658.1 - 1.9e-09 37.8 7.0 0.013 15.9 0.0 6.9 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 RJW71658.1 - 4.6e-09 35.8 16.2 0.46 10.9 0.0 10.1 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 RJW71658.1 - 3.1e-08 33.9 15.7 0.53 10.8 0.1 8.3 8 2 1 9 9 9 4 HEAT-like repeat Cnd1 PF12717.7 RJW71658.1 - 0.00039 20.5 10.2 0.48 10.4 0.0 5.3 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.10 RJW71658.1 - 0.0099 15.7 1.8 17 5.2 0.0 4.9 4 2 1 5 5 5 1 TATA-binding protein interacting (TIP20) ParcG PF10274.9 RJW71658.1 - 0.015 15.4 0.5 3.3 7.8 0.1 3.3 3 0 0 3 3 3 0 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 RJW71658.1 - 0.11 13.1 0.1 6.3 7.5 0.1 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region CHORD PF04968.12 RJW71659.1 - 5.3e-52 174.4 24.3 2.6e-26 92.1 10.7 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 RJW71659.1 - 1.4e-10 42.0 0.0 3.6e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 CS domain BTK PF00779.19 RJW71659.1 - 0.022 14.6 13.6 0.38 10.6 0.5 3.3 2 1 0 2 2 2 0 BTK motif EspF PF04806.12 RJW71659.1 - 0.073 13.5 8.0 0.15 12.5 8.0 1.4 1 0 0 1 1 1 0 EspF protein repeat Rho_GDI PF02115.17 RJW71660.1 - 2.9e-49 167.5 0.0 4.4e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor TRIQK PF15168.6 RJW71661.1 - 0.085 12.8 0.5 0.17 11.8 0.5 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family E1_DerP2_DerF2 PF02221.15 RJW71663.1 - 3.2e-24 85.9 4.0 6.1e-15 55.8 0.2 2.1 2 0 0 2 2 2 2 ML domain DUF222 PF02720.17 RJW71663.1 - 0.0037 16.8 0.1 0.0056 16.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF222) TFIIA PF03153.13 RJW71664.1 - 1.1e-57 197.0 2.5 1.5e-41 143.8 0.2 2.9 2 1 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit MPP6 PF10175.9 RJW71664.1 - 2.1 8.9 3.5 1.2 9.7 0.3 2.0 2 0 0 2 2 2 0 M-phase phosphoprotein 6 UPF0506 PF11703.8 RJW71667.1 - 8.8e-27 93.3 39.4 2.1e-13 50.4 13.2 2.0 2 0 0 2 2 2 2 UPF0506 Conotoxin_I2 PF17557.2 RJW71667.1 - 0.061 13.4 8.8 0.061 13.4 8.8 4.3 3 1 1 4 4 4 0 I2-superfamily conotoxins Toxin_21 PF08091.11 RJW71667.1 - 1.8 8.5 40.1 0.19 11.7 8.2 5.0 3 2 0 3 3 3 0 Spider insecticidal peptide Syja_N PF02383.18 RJW71668.1 - 6e-65 219.7 0.0 8.2e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 RJW71668.1 - 1.5e-15 57.4 0.5 3.1e-15 56.3 0.5 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family dbPDZ_assoc PF16610.5 RJW71668.1 - 0.056 13.7 1.1 0.14 12.4 1.1 1.6 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 DUF1866 PF08952.11 RJW71668.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Pantoate_ligase PF02569.15 RJW71668.1 - 0.19 10.9 0.2 0.35 10.1 0.2 1.3 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Tubulin PF00091.25 RJW71672.1 - 2.2e-68 230.4 0.0 3.5e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW71672.1 - 2.9e-43 147.0 0.1 4.6e-43 146.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RJW71672.1 - 1.4e-05 25.4 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RJW71672.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RJW71672.1 - 0.023 13.9 0.1 0.047 12.9 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Gp_dh_C PF02800.20 RJW71674.1 - 8e-69 230.2 0.0 1.2e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 RJW71674.1 - 3e-36 123.8 0.0 6.7e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RJW71674.1 - 0.056 13.6 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 RJW71674.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain BAR_3 PF16746.5 RJW71676.1 - 4.5e-09 36.4 8.5 6.4e-09 35.9 8.5 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 RJW71676.1 - 1.2e-07 32.2 0.1 3.9e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 PH domain BLOC1S3 PF15753.5 RJW71676.1 - 0.0015 18.7 0.2 0.0028 17.8 0.2 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 YkyA PF10368.9 RJW71676.1 - 0.017 14.8 3.4 0.027 14.1 3.4 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF327 PF03885.13 RJW71676.1 - 0.051 13.5 3.3 0.078 12.9 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF327) Sec8_exocyst PF04048.14 RJW71676.1 - 0.056 13.3 0.8 0.12 12.3 0.8 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Phage_GPO PF05929.11 RJW71676.1 - 3.3 7.3 6.6 5.6 6.5 6.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RabGAP-TBC PF00566.18 RJW71677.1 - 1.4e-12 47.7 0.6 2.4e-12 47.0 0.6 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40_like PF17005.5 RJW71677.1 - 0.00057 19.3 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 WD40-like domain Mei5 PF10376.9 RJW71677.1 - 0.024 14.5 3.4 0.037 13.9 3.4 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein WD40 PF00400.32 RJW71677.1 - 0.042 14.7 6.6 6.5 7.8 0.0 5.1 5 0 0 5 5 5 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW71677.1 - 0.068 13.5 0.1 0.56 10.5 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Glutaredoxin PF00462.24 RJW71678.1 - 7.2e-08 32.5 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 RJW71678.1 - 0.00035 20.9 0.1 0.00048 20.5 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_7 PF13899.6 RJW71678.1 - 0.062 13.5 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like RVT_1 PF00078.27 RJW71681.1 - 0.00016 21.3 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ELL PF10390.9 RJW71682.1 - 2.4e-14 53.5 0.0 2.7e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL Guanylate_kin PF00625.21 RJW71683.1 - 1.6e-30 106.1 0.0 3e-30 105.3 0.0 1.4 1 1 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 RJW71683.1 - 9.4e-07 28.4 0.0 2.4e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 RJW71683.1 - 2.8e-06 26.8 0.0 6.8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PDZ PF00595.24 RJW71683.1 - 3.8e-06 27.2 0.1 7.2e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 RJW71683.1 - 6.8e-06 25.8 2.2 1.1e-05 25.2 0.0 2.6 3 0 0 3 3 3 1 Variant SH3 domain PDZ_6 PF17820.1 RJW71683.1 - 0.00044 20.0 0.1 0.00092 19.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW71683.1 - 0.0033 17.7 0.0 0.0062 16.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 RJW71683.1 - 0.033 14.2 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Zn_ribbon_17 PF17120.5 RJW71684.1 - 4.7e-08 32.5 13.6 4.8e-08 32.5 11.4 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PhnA_Zn_Ribbon PF08274.12 RJW71684.1 - 9.5e-06 25.5 0.0 7.8e-05 22.5 0.0 2.6 3 1 0 3 3 3 1 PhnA Zinc-Ribbon RWD PF05773.22 RJW71684.1 - 5.5e-05 23.4 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 RWD domain zinc_ribbon_16 PF17034.5 RJW71684.1 - 0.016 15.5 19.5 0.029 14.6 12.8 2.9 1 1 1 2 2 2 0 Zinc-ribbon like family RPS31 PF17067.5 RJW71684.1 - 1.5 9.0 5.6 2.4 8.4 0.9 3.0 2 0 0 2 2 2 0 Ribosomal protein S31e zf-RRN7 PF11781.8 RJW71684.1 - 3.8 7.3 7.0 0.52 10.0 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RING_2 PF13639.6 RJW71685.1 - 1e-06 28.9 15.3 1e-06 28.9 15.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 RJW71685.1 - 4.1e-06 26.6 12.1 4.1e-06 26.6 12.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW71685.1 - 8.4e-06 25.7 8.7 8.4e-06 25.7 8.7 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RJW71685.1 - 2.1e-05 24.3 14.5 2.1e-05 24.3 14.5 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW71685.1 - 0.00021 21.1 13.6 0.00021 21.1 13.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RJW71685.1 - 0.0017 18.4 13.3 0.0017 18.4 13.3 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RJW71685.1 - 0.0025 18.1 9.6 0.0025 18.1 9.6 2.9 3 0 0 3 3 3 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RJW71685.1 - 0.0036 17.1 15.3 0.14 12.1 15.8 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 RJW71685.1 - 0.016 14.8 13.6 0.022 14.4 7.7 2.9 2 1 1 3 3 3 0 P-11 zinc finger zf-RING_5 PF14634.6 RJW71685.1 - 0.12 12.3 19.2 0.065 13.2 15.0 2.5 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_4 PF14570.6 RJW71685.1 - 1.1 9.1 15.2 1.5 8.7 9.0 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain PHD_4 PF16866.5 RJW71686.1 - 0.24 11.5 7.9 0.39 10.8 7.9 1.3 1 0 0 1 1 1 0 PHD-finger zf-C2H2 PF00096.26 RJW71687.1 - 1.9e-11 43.7 18.2 0.00062 20.1 2.0 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW71687.1 - 1.5e-08 34.8 16.1 0.014 16.2 2.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW71687.1 - 0.00041 20.6 1.6 0.00041 20.6 1.6 4.3 4 0 0 4 4 4 2 Zinc-finger double domain BolA PF01722.18 RJW71687.1 - 0.016 15.5 0.5 0.051 13.9 0.5 1.9 1 0 0 1 1 1 0 BolA-like protein zf-C2H2_6 PF13912.6 RJW71687.1 - 0.029 14.4 12.2 0.092 12.8 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Androgen_recep PF02166.16 RJW71687.1 - 0.13 11.1 9.6 0.26 10.1 9.6 1.4 1 0 0 1 1 1 0 Androgen receptor zf-C2H2_jaz PF12171.8 RJW71687.1 - 0.14 12.4 11.5 11 6.4 0.8 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SNAP PF14938.6 RJW71687.1 - 0.16 11.4 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP zf-C2H2_11 PF16622.5 RJW71687.1 - 0.38 10.6 0.1 0.38 10.6 0.1 3.1 2 1 1 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 RJW71687.1 - 0.48 10.9 15.5 1.4 9.4 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 RJW71687.1 - 0.89 10.2 12.1 2.3 8.9 0.1 3.8 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 RJW71687.1 - 6.4 6.8 7.0 28 4.7 0.0 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger EF-hand_7 PF13499.6 RJW71688.1 - 0.023 15.1 0.3 0.62 10.6 0.7 2.4 1 1 1 2 2 2 0 EF-hand domain pair RT_RNaseH PF17917.1 RJW71689.1 - 1.9e-18 66.7 0.0 3.7e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW71689.1 - 5.5e-15 55.2 0.1 1.4e-14 53.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RJW71689.1 - 1.1e-06 28.8 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain GIT1_C PF12205.8 RJW71690.1 - 7.1e-30 103.5 0.1 7.1e-30 103.5 0.1 1.8 2 0 0 2 2 1 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_SHD PF08518.11 RJW71690.1 - 7.5e-21 73.4 1.3 1e-11 44.2 0.5 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ArfGap PF01412.18 RJW71690.1 - 4.1e-18 65.6 0.4 1.7e-17 63.6 0.4 2.0 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_5 PF13857.6 RJW71690.1 - 5.8e-08 32.9 0.1 1.8e-07 31.3 0.0 2.0 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW71690.1 - 2.7e-06 27.8 0.0 6e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW71690.1 - 5.2e-05 23.7 0.0 0.00025 21.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF4763 PF15960.5 RJW71690.1 - 0.013 14.8 1.6 0.029 13.7 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Ank_3 PF13606.6 RJW71690.1 - 0.054 14.1 0.0 0.32 11.7 0.0 2.4 2 0 0 2 2 1 0 Ankyrin repeat Ank PF00023.30 RJW71690.1 - 0.06 13.8 0.1 0.6 10.7 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Shugoshin_N PF07558.11 RJW71690.1 - 0.11 12.4 1.0 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region RVT_1 PF00078.27 RJW71690.1 - 0.21 11.1 0.0 0.46 10.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ATG16 PF08614.11 RJW71690.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.6 3 0 0 3 3 2 0 Autophagy protein 16 (ATG16) SKA1 PF07160.12 RJW71690.1 - 0.29 11.0 4.4 0.86 9.4 4.4 1.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Spc7 PF08317.11 RJW71690.1 - 0.33 9.8 1.5 0.73 8.7 1.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 RJW71690.1 - 0.55 9.8 2.1 0.58 9.7 0.6 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 RJW71690.1 - 0.98 9.9 5.5 0.17 12.4 0.6 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Forkhead PF00250.18 RJW71692.1 - 1.2e-29 102.4 0.0 2.8e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain zf-MYND PF01753.18 RJW71694.1 - 0.00063 19.8 9.3 0.0015 18.6 9.3 1.7 1 0 0 1 1 1 1 MYND finger NinF PF05810.12 RJW71694.1 - 0.096 12.6 2.3 0.29 11.1 2.3 1.7 1 0 0 1 1 1 0 NinF protein zf-HIT PF04438.16 RJW71694.1 - 4.8 7.1 13.1 1.4 8.8 9.6 1.9 2 0 0 2 2 2 0 HIT zinc finger rve PF00665.26 RJW71695.1 - 5e-14 52.5 0.1 3.1e-12 46.7 0.1 2.5 1 1 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW71695.1 - 7.2e-12 45.2 0.4 1.5e-11 44.2 0.3 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RJW71695.1 - 1.2e-05 25.4 0.9 4.7e-05 23.5 0.3 2.2 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 RJW71695.1 - 0.00068 19.4 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RecU PF03838.14 RJW71695.1 - 0.079 13.0 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Recombination protein U Pkinase_Tyr PF07714.17 RJW71696.1 - 2.9e-23 82.5 0.1 3.4e-21 75.7 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 RJW71696.1 - 9e-23 81.0 0.0 4.6e-21 75.4 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain TGF_beta_GS PF08515.12 RJW71696.1 - 4.1e-13 48.6 0.7 4.1e-13 48.6 0.7 1.9 2 0 0 2 2 2 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 RJW71696.1 - 0.00069 20.7 5.7 0.002 19.2 5.7 1.8 1 0 0 1 1 1 1 Activin types I and II receptor domain APH PF01636.23 RJW71696.1 - 0.00079 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RJW71696.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 RJW71696.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Helicase_C PF00271.31 RJW71699.1 - 4.3e-12 46.4 0.0 9.1e-11 42.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 RJW71699.1 - 0.00013 22.5 0.0 0.00045 20.8 0.0 2.0 1 1 0 1 1 1 1 Helix-hairpin-helix domain DEAD PF00270.29 RJW71699.1 - 0.00027 20.8 0.0 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Cdd1 PF11731.8 RJW71699.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus DUF4332 PF14229.6 RJW71699.1 - 0.14 12.4 0.1 0.38 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) ResIII PF04851.15 RJW71699.1 - 0.23 11.4 0.0 0.44 10.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MOZART1 PF12554.8 RJW71701.1 - 2.6e-19 68.7 0.4 3.4e-19 68.4 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated YebG PF07130.12 RJW71701.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 YebG protein HEAT_2 PF13646.6 RJW71702.1 - 2.5e-09 37.4 8.4 1.1e-05 25.7 0.5 3.9 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 RJW71702.1 - 1.9e-07 31.3 1.0 0.12 12.5 0.0 4.3 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RJW71702.1 - 3.7e-07 29.8 14.5 0.29 11.5 0.2 6.6 6 0 0 6 6 6 4 HEAT repeat Adaptin_N PF01602.20 RJW71702.1 - 0.015 13.9 0.7 2.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Adaptin N terminal region RasGEF_N_2 PF14663.6 RJW71702.1 - 0.081 13.3 1.1 11 6.4 0.1 2.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.6 RJW71702.1 - 0.14 12.7 8.9 1.5 9.4 0.2 4.7 5 0 0 5 5 5 0 HEAT-like repeat Acyl-CoA_dh_1 PF00441.24 RJW71705.1 - 6.5e-28 97.8 0.4 8.9e-28 97.4 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RJW71705.1 - 1.5e-26 93.3 0.0 2.4e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RJW71705.1 - 1.9e-22 79.3 0.0 3.2e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RJW71705.1 - 4.7e-08 33.4 0.3 8.3e-08 32.6 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Tipalpha PF16753.5 RJW71706.1 - 0.0028 17.5 0.1 0.042 13.7 0.0 2.2 2 0 0 2 2 2 1 TNF-alpha-Inducing protein of Helicobacter Arf PF00025.21 RJW71707.1 - 2.1e-63 212.9 0.0 2.4e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RJW71707.1 - 4.5e-10 39.8 0.0 9.6e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RJW71707.1 - 1.3e-09 37.7 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 RJW71707.1 - 2.2e-09 37.1 0.0 3.1e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 RJW71707.1 - 2.3e-08 34.1 0.0 3.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 RJW71707.1 - 4.7e-08 32.6 0.1 1.1e-05 24.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit cobW PF02492.19 RJW71707.1 - 0.00019 21.0 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 RJW71707.1 - 0.0014 18.2 0.1 0.05 13.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RJW71707.1 - 0.0024 17.3 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 RJW71707.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PPK2 PF03976.14 RJW71707.1 - 0.22 11.0 0.0 0.51 9.8 0.0 1.5 1 1 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Perm-CXXC PF15629.6 RJW71708.1 - 0.0013 18.9 0.2 2.8 8.3 0.0 2.5 2 0 0 2 2 2 2 Permuted single zf-CXXC unit Toxin-deaminase PF14424.6 RJW71708.1 - 0.0048 17.0 0.1 2.4 8.2 0.0 2.2 2 0 0 2 2 2 2 The BURPS668_1122 family of deaminases Strep_pep PF14404.6 RJW71708.1 - 0.0098 16.1 0.0 6 7.2 0.0 2.6 3 0 0 3 3 3 2 Ribosomally synthesized peptide in Streptomyces species RuBisCO_small PF00101.20 RJW71708.1 - 0.011 15.7 0.1 5 7.2 0.0 2.3 1 1 1 2 2 2 0 Ribulose bisphosphate carboxylase, small chain RebB PF11747.8 RJW71708.1 - 0.15 12.2 0.2 25 5.1 0.0 2.3 2 0 0 2 2 2 0 Killing trait MCM PF00493.23 RJW71710.1 - 1.5e-97 325.1 0.0 2.3e-97 324.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RJW71710.1 - 5.8e-37 126.3 0.5 1.1e-36 125.4 0.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RJW71710.1 - 1.1e-26 93.0 0.2 2.5e-26 91.9 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RJW71710.1 - 5.7e-16 59.0 0.0 2.1e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 RJW71710.1 - 3.2e-08 33.7 0.0 9.7e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RJW71710.1 - 8.6e-07 28.5 2.3 2.4e-05 23.8 0.0 2.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RJW71710.1 - 0.0006 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RJW71710.1 - 0.0082 15.9 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RVT_1 PF00078.27 RJW71711.1 - 5e-35 121.0 0.0 1.1e-34 119.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SRP_TPR_like PF17004.5 RJW71711.1 - 1.3e-27 96.1 2.8 1.3e-27 96.1 2.8 2.1 3 0 0 3 3 3 1 Putative TPR-like repeat SRP72 PF08492.12 RJW71711.1 - 2.8e-19 69.3 6.3 9.6e-19 67.6 6.3 2.0 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_19 PF14559.6 RJW71711.1 - 0.00014 22.3 16.5 0.0059 17.1 0.4 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW71711.1 - 0.00019 21.6 13.7 0.00088 19.5 1.1 5.5 6 1 2 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RJW71711.1 - 0.00061 19.7 5.3 1.3 9.3 0.1 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Hjc PF01870.18 RJW71711.1 - 0.015 15.3 0.5 0.037 14.0 0.1 1.9 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) TPR_16 PF13432.6 RJW71711.1 - 1.5 9.6 15.1 5.7 7.7 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat GCP_C_terminal PF04130.13 RJW71712.1 - 2.4e-20 73.2 1.1 4.9e-20 72.2 1.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 RJW71712.1 - 2.8e-10 40.3 1.3 3.6e-09 36.7 0.3 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal RVT_1 PF00078.27 RJW71713.1 - 7e-08 32.2 0.0 3.9e-05 23.3 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) HAP1_N PF04849.13 RJW71713.1 - 0.0012 18.1 13.7 0.0012 18.1 13.7 5.5 2 1 1 5 5 5 2 HAP1 N-terminal conserved region Baculo_PEP_C PF04513.12 RJW71713.1 - 0.025 14.6 35.1 0.2 11.7 5.2 6.3 4 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 RJW71713.1 - 0.13 12.9 44.0 0.18 12.5 0.2 7.2 5 2 3 8 8 8 0 Initiation control protein YabA LPP PF04728.13 RJW71713.1 - 0.46 10.9 29.0 5.3 7.5 0.4 8.1 8 0 0 8 8 7 0 Lipoprotein leucine-zipper FPP PF05911.11 RJW71713.1 - 1.9 6.6 59.0 0.32 9.1 8.5 3.3 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil Pox_A_type_inc PF04508.12 RJW71713.1 - 3 7.9 5.0 95 3.1 0.0 4.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat HALZ PF02183.18 RJW71713.1 - 4 7.7 14.8 61 4.0 1.7 6.0 6 0 0 6 6 6 0 Homeobox associated leucine zipper ADIP PF11559.8 RJW71713.1 - 5.5 7.1 63.3 0.15 12.1 12.1 6.1 3 1 1 6 6 6 0 Afadin- and alpha -actinin-Binding EzrA PF06160.12 RJW71713.1 - 7.8 4.5 43.7 0.05 11.8 3.8 4.6 3 1 1 4 4 4 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 RJW71713.1 - 9.8 5.0 74.8 1.4 7.7 11.7 5.4 3 1 4 7 7 7 0 Spc7 kinetochore protein Complex1_30kDa PF00329.19 RJW71714.1 - 3.8e-40 137.3 0.0 5.3e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit SPRY PF00622.28 RJW71715.1 - 6.6e-14 52.1 0.0 1e-13 51.4 0.0 1.3 1 1 0 1 1 1 1 SPRY domain Pkinase PF00069.25 RJW71716.1 - 2.5e-69 233.6 0.0 3.6e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW71716.1 - 5.5e-31 107.8 0.0 9.4e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DCX PF03607.17 RJW71716.1 - 2e-05 24.6 0.1 7.7e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Doublecortin Kinase-like PF14531.6 RJW71716.1 - 0.00014 21.3 0.0 0.00047 19.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RJW71716.1 - 0.0055 15.5 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RJW71716.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 RJW71716.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 RJW71716.1 - 0.15 11.6 0.1 0.39 10.3 0.1 1.7 1 0 0 1 1 1 0 RIO1 family Kinesin PF00225.23 RJW71718.1 - 5.8e-105 350.9 0.3 9.7e-105 350.2 0.3 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RJW71718.1 - 1.7e-19 70.2 0.1 9.9e-18 64.5 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 RJW71718.1 - 1.7e-06 28.3 4.4 1.7e-06 28.3 4.4 3.2 3 1 1 4 4 4 2 Kinesin-associated KIF1B PF12423.8 RJW71718.1 - 0.00061 20.2 0.6 0.0026 18.2 0.6 2.2 1 0 0 1 1 1 1 Kinesin protein 1B AAA_32 PF13654.6 RJW71718.1 - 0.00072 18.5 7.4 0.0017 17.2 7.4 1.6 1 0 0 1 1 1 1 AAA domain FHA PF00498.26 RJW71718.1 - 0.021 15.1 0.1 0.74 10.2 0.0 3.0 3 0 0 3 3 3 0 FHA domain THF_DHG_CYH PF00763.23 RJW71718.1 - 0.092 13.0 1.3 0.29 11.4 1.3 1.9 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 7tm_1 PF00001.21 RJW71721.1 - 9.1e-19 67.8 18.5 1.2e-18 67.4 18.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) WD40 PF00400.32 RJW71722.1 - 1.2e-08 35.5 0.5 0.015 16.2 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat I-set PF07679.16 RJW71726.1 - 1.2e-55 185.5 0.1 3.1e-12 46.4 0.0 5.5 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 RJW71726.1 - 5.5e-55 183.9 8.9 9.5e-14 51.8 0.0 6.0 5 0 0 5 5 5 4 Immunoglobulin domain Ig_2 PF13895.6 RJW71726.1 - 2.2e-39 133.7 5.0 4.2e-10 39.8 0.0 5.6 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 RJW71726.1 - 1.5e-27 95.6 0.9 1.3e-08 34.9 0.0 6.0 5 1 1 6 6 6 4 Immunoglobulin domain fn3 PF00041.21 RJW71726.1 - 5.5e-25 87.5 8.3 2.2e-08 34.3 0.1 6.3 6 0 0 6 6 6 3 Fibronectin type III domain V-set PF07686.17 RJW71726.1 - 5.2e-15 55.5 5.9 0.064 13.4 0.0 8.0 4 4 0 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 RJW71726.1 - 8.1e-10 38.6 0.3 0.0064 16.5 0.0 4.2 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RJW71726.1 - 4.7e-05 23.4 0.0 0.037 14.1 0.0 3.2 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RJW71726.1 - 0.00012 21.6 0.0 0.9 9.1 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 RJW71726.1 - 0.00017 21.9 0.0 0.42 11.0 0.0 4.1 4 1 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 RJW71726.1 - 0.0043 17.4 0.2 14 6.1 0.0 4.3 4 1 0 4 4 4 1 Immunoglobulin C1-set domain Pur_ac_phosph_N PF16656.5 RJW71726.1 - 0.019 15.5 0.1 40 4.9 0.0 3.8 2 1 1 3 3 3 0 Purple acid Phosphatase, N-terminal domain Mt_ATP-synt_D PF05873.12 RJW71727.1 - 8.3e-26 90.7 0.5 1.1e-25 90.3 0.5 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Snf7 PF03357.21 RJW71727.1 - 0.016 14.8 0.9 0.016 14.8 0.9 1.6 2 0 0 2 2 2 0 Snf7 Utp13 PF08625.11 RJW71727.1 - 0.028 14.3 0.0 0.33 10.9 0.0 2.1 1 1 1 2 2 2 0 Utp13 specific WD40 associated domain KELK PF15796.5 RJW71727.1 - 0.097 13.1 0.8 0.23 12.0 0.8 1.6 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase V-SNARE_C PF12352.8 RJW71727.1 - 0.1 12.9 0.1 0.58 10.5 0.1 2.1 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Tubulin PF00091.25 RJW71728.1 - 1.7e-15 57.7 0.0 3.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 RJW71728.1 - 0.16 11.1 0.2 0.27 10.4 0.2 1.3 1 0 0 1 1 1 0 Tubulin like Syja_N PF02383.18 RJW71730.1 - 5.9e-69 232.8 0.0 1.6e-68 231.4 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain PI3Ka PF00613.20 RJW71731.1 - 1.9e-14 53.5 0.2 1.9e-13 50.2 0.2 2.1 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 RJW71731.1 - 2.5e-09 37.2 0.0 5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 RJW71731.1 - 0.0001 22.4 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain CSTF2_hinge PF14327.6 RJW71731.1 - 0.11 13.0 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Tubulin PF00091.25 RJW71732.1 - 9.6e-59 198.9 0.0 1.6e-58 198.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW71732.1 - 1.3e-43 148.2 0.1 2e-43 147.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW71732.1 - 0.022 14.5 0.1 0.065 12.9 0.0 1.8 2 0 0 2 2 2 0 Tubulin domain Tubulin_2 PF13809.6 RJW71732.1 - 0.029 13.6 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin like WD40 PF00400.32 RJW71734.1 - 9.9e-38 127.5 11.7 2.1e-07 31.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW71734.1 - 3.5e-17 62.5 0.5 0.00015 22.0 0.0 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW71734.1 - 9.9e-08 31.3 0.4 0.28 10.1 0.0 4.1 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 RJW71734.1 - 0.0048 16.8 0.8 3.5 7.7 0.0 3.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 RJW71734.1 - 0.0073 14.9 0.3 0.6 8.6 0.2 2.7 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 RJW71734.1 - 0.041 12.6 0.1 3.6 6.2 0.0 2.9 2 1 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.6 RJW71734.1 - 0.046 13.1 0.2 3.5 6.9 0.0 3.1 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 RJW71734.1 - 0.052 13.2 0.3 1 9.1 0.1 3.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Nup160 PF11715.8 RJW71734.1 - 0.76 8.3 3.4 3 6.4 0.2 2.7 2 1 2 4 4 4 0 Nucleoporin Nup120/160 zf-HC5HC2H PF13771.6 RJW71735.1 - 3.1e-09 37.0 0.8 1e-08 35.3 0.8 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RJW71735.1 - 3e-07 30.6 0.3 3e-07 30.6 0.3 2.0 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 RJW71735.1 - 0.7 9.8 11.0 0.13 12.2 2.9 3.1 3 0 0 3 3 3 0 PHD-finger Oxidored_molyb PF00174.19 RJW71736.1 - 5e-47 159.7 0.0 9.6e-47 158.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 RJW71736.1 - 6.3e-33 113.7 0.0 1.4e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 RJW71736.1 - 0.04 13.9 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 BNR/Asp-box repeat Ndc1_Nup PF09531.10 RJW71738.1 - 1.1e-13 50.8 0.0 7.3e-13 48.1 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Bac_chlorC PF02043.17 RJW71738.1 - 0.086 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein Homeodomain PF00046.29 RJW71739.1 - 1.3e-21 76.2 5.4 3.1e-21 75.0 5.4 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW71739.1 - 0.11 12.4 0.3 0.4 10.6 0.3 2.0 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 RJW71739.1 - 1.2 8.7 5.5 1.6 8.2 1.0 3.0 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez RPEL PF02755.15 RJW71740.1 - 6e-16 57.6 1.2 5.3e-09 35.5 0.2 2.7 2 0 0 2 2 2 2 RPEL repeat PilX PF13681.6 RJW71741.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term SNF2_N PF00176.23 RJW71742.1 - 5.9e-75 252.2 0.0 8.5e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 RJW71742.1 - 0.0001 22.0 8.0 0.0001 22.0 8.0 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 RJW71742.1 - 0.0019 18.1 5.7 0.0078 16.1 5.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 RJW71742.1 - 0.0021 17.9 6.4 0.0021 17.9 6.4 2.9 2 0 0 2 2 2 1 PHD-finger Helicase_C PF00271.31 RJW71742.1 - 0.0029 17.9 0.0 0.0079 16.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_4 PF14570.6 RJW71742.1 - 0.016 15.0 9.6 0.017 14.9 5.2 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF4420 PF14390.6 RJW71742.1 - 0.14 11.3 0.7 0.29 10.3 0.7 1.4 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) Prok-RING_1 PF14446.6 RJW71742.1 - 1.1 9.2 15.2 1.4 8.9 0.7 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.6 RJW71742.1 - 5.7 6.9 14.5 3.2 7.7 10.7 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW71742.1 - 8.6 6.8 21.8 0.052 13.9 10.6 3.1 2 1 0 2 2 2 0 Ring finger domain Ank_4 PF13637.6 RJW71743.1 - 9.8e-13 48.3 0.0 1.8e-05 25.2 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RJW71743.1 - 3e-12 46.5 0.2 1.1e-05 25.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW71743.1 - 2.3e-10 40.9 0.0 9.4e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW71743.1 - 6.7e-09 35.3 0.0 0.0087 16.5 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat RVT_1 PF00078.27 RJW71743.1 - 2e-07 30.7 0.0 4.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank PF00023.30 RJW71743.1 - 2.3e-06 27.8 0.0 0.0022 18.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Spp-24 PF07448.11 RJW71743.1 - 0.0011 19.1 0.2 0.0045 17.1 0.2 2.0 1 0 0 1 1 1 1 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Sad1_UNC PF07738.13 RJW71743.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Frizzled PF01534.17 RJW71745.1 - 2.5e-57 194.4 10.4 2.1e-26 92.8 4.9 3.1 3 0 0 3 3 3 3 Frizzled/Smoothened family membrane region Fz PF01392.22 RJW71745.1 - 4.5e-21 75.6 1.4 4.5e-21 75.6 1.4 2.4 2 0 0 2 2 2 1 Fz domain DHC_N1 PF08385.12 RJW71747.1 - 5.4e-112 375.3 4.0 4.6e-102 342.5 2.1 2.1 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 ArsC PF03960.15 RJW71747.1 - 0.11 12.5 0.1 0.35 10.9 0.1 1.8 1 0 0 1 1 1 0 ArsC family Syndecan PF01034.20 RJW71748.1 - 0.00016 21.5 0.1 0.00025 20.9 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain Adeno_E3_CR2 PF02439.15 RJW71748.1 - 0.00041 20.0 6.3 0.00059 19.5 6.3 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 RJW71748.1 - 0.0006 19.9 0.0 0.0007 19.6 0.0 1.2 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 RJW71748.1 - 0.00083 20.2 0.1 0.00099 19.9 0.1 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CYYR1 PF10873.8 RJW71748.1 - 0.0019 18.7 0.5 0.0023 18.4 0.5 1.1 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 DUF4006 PF13179.6 RJW71748.1 - 0.0033 17.3 0.1 0.0043 16.9 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF4006) Orthoreo_P10 PF07204.11 RJW71748.1 - 0.0036 17.2 1.3 0.0051 16.7 1.1 1.4 1 1 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 VSP PF03302.13 RJW71748.1 - 0.0055 15.6 0.4 0.0064 15.4 0.4 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Shisa PF13908.6 RJW71748.1 - 0.0073 16.6 0.0 0.0082 16.4 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator 7TM_GPCR_Srw PF10324.9 RJW71748.1 - 0.0074 15.6 0.0 0.0084 15.4 0.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw PARM PF17061.5 RJW71748.1 - 0.0088 16.2 3.0 0.0088 16.2 3.0 1.7 1 1 1 2 2 2 1 PARM Amnionless PF14828.6 RJW71748.1 - 0.0096 14.8 0.0 0.01 14.7 0.0 1.0 1 0 0 1 1 1 1 Amnionless Comm PF15957.5 RJW71748.1 - 0.014 15.8 0.0 0.017 15.5 0.0 1.1 1 0 0 1 1 1 0 Commissureless TMEM154 PF15102.6 RJW71748.1 - 0.016 15.1 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family TRP PF06011.12 RJW71748.1 - 0.017 13.9 0.1 0.02 13.6 0.1 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel LRR19-TM PF15176.6 RJW71748.1 - 0.02 14.9 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain TMIE PF16038.5 RJW71748.1 - 0.024 14.5 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 TMIE protein Tweety PF04906.13 RJW71748.1 - 0.027 13.1 0.2 0.03 13.0 0.2 1.1 1 0 0 1 1 1 0 Tweety FAM163 PF15069.6 RJW71748.1 - 0.032 14.7 0.1 0.043 14.3 0.1 1.2 1 0 0 1 1 1 0 FAM163 family UPF0560 PF10577.9 RJW71748.1 - 0.036 12.6 0.1 0.04 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MLANA PF14991.6 RJW71748.1 - 0.041 14.2 0.0 0.048 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A DUF4446 PF14584.6 RJW71748.1 - 0.049 13.6 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TMEM132D_C PF15706.5 RJW71748.1 - 0.062 13.1 0.1 0.085 12.6 0.1 1.2 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ASFV_J13L PF05568.11 RJW71748.1 - 0.067 13.0 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Glycophorin_A PF01102.18 RJW71748.1 - 0.083 13.1 3.8 0.09 13.0 3.4 1.4 1 1 0 1 1 1 0 Glycophorin A WBP-1 PF11669.8 RJW71748.1 - 0.085 13.5 0.0 0.096 13.3 0.0 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 SIT PF15330.6 RJW71748.1 - 0.096 13.1 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Cortexin PF11057.8 RJW71748.1 - 0.14 12.1 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Cortexin of kidney LAT PF15234.6 RJW71748.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells DUF4349 PF14257.6 RJW71748.1 - 0.21 11.0 0.7 0.31 10.5 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF4690 PF15756.5 RJW71748.1 - 0.62 10.7 4.6 0.43 11.2 2.8 1.6 1 1 0 2 2 2 0 Small Novel Rich in Cartilage DUF2970 PF11174.8 RJW71748.1 - 0.8 9.6 9.1 1.2 9.0 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Mid2 PF04478.12 RJW71748.1 - 0.9 9.4 9.6 0.99 9.2 8.4 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 RJW71748.1 - 6.7 6.2 11.1 12 5.4 11.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_1 PF00018.28 RJW71752.1 - 5.2e-06 26.0 0.0 2.6e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 SH3 domain PTB PF08416.13 RJW71752.1 - 0.0009 19.4 0.6 0.0016 18.6 0.6 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_10 PF17902.1 RJW71752.1 - 0.033 14.2 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.6 RJW71752.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain SH3_3 PF08239.11 RJW71752.1 - 0.15 12.3 0.1 0.44 10.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain HpcH_HpaI PF03328.14 RJW71753.1 - 4.5e-32 111.0 0.0 3.6e-31 108.0 0.0 2.3 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 RJW71753.1 - 0.00018 20.8 0.0 0.0097 15.1 0.0 2.4 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF2197 PF09963.9 RJW71753.1 - 0.14 12.5 1.1 0.39 11.0 1.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) SWIB PF02201.18 RJW71754.1 - 1.6e-21 75.9 0.0 5.4e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain fn3 PF00041.21 RJW71757.1 - 1.4e-06 28.6 0.0 2.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain WD40 PF00400.32 RJW71758.1 - 4.1e-23 81.2 21.7 0.00011 22.9 0.1 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW71758.1 - 2.2e-09 37.5 9.1 0.0014 18.9 0.5 4.4 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW71758.1 - 0.00026 20.1 0.0 0.014 14.4 0.0 2.9 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DSPn PF14671.6 RJW71759.1 - 1.8e-52 177.6 2.8 5.6e-52 175.9 1.7 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 RJW71759.1 - 1.2e-12 47.8 0.0 2.8e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RJW71759.1 - 4.5e-05 23.1 0.6 0.0001 22.0 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RJW71759.1 - 6.1e-05 23.2 0.2 0.0033 17.5 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate FGGY_N PF00370.21 RJW71760.1 - 2.3e-67 227.2 0.1 3.2e-67 226.6 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 RJW71760.1 - 1.8e-41 142.1 1.5 8.2e-41 139.9 1.4 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1177 PF06675.11 RJW71760.1 - 0.072 11.9 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) FAM76 PF16046.5 RJW71761.1 - 1.7e-78 264.1 26.2 3.1e-78 263.2 26.2 1.4 1 0 0 1 1 1 1 FAM76 protein DUF4600 PF15372.6 RJW71761.1 - 0.0058 17.1 2.8 0.0058 17.1 2.8 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4600) MPS2 PF17060.5 RJW71761.1 - 1.1 8.5 8.6 1.7 7.8 8.6 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 MalF_P2 PF14785.6 RJW71761.1 - 1.5 8.9 5.3 0.58 10.2 2.2 1.8 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain DZR PF12773.7 RJW71761.1 - 2.2 8.4 23.7 79 3.4 7.8 3.0 1 1 2 3 3 3 0 Double zinc ribbon DivIC PF04977.15 RJW71761.1 - 3 7.7 10.9 7.5 6.4 1.6 2.4 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 RJW71761.1 - 3.4 8.2 15.5 4.5 7.8 3.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Smr PF01713.21 RJW71762.1 - 2.6e-07 30.9 0.0 1.2e-06 28.8 0.0 2.2 2 0 0 2 2 2 1 Smr domain AAA_33 PF13671.6 RJW71762.1 - 7.7e-05 22.9 0.0 0.00024 21.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RJW71762.1 - 0.0039 17.7 0.0 0.0098 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RJW71762.1 - 0.0046 16.9 0.0 0.022 14.7 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 RJW71762.1 - 0.0066 16.9 1.5 0.022 15.1 0.0 2.8 4 0 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.27 RJW71762.1 - 0.024 15.1 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KTI12 PF08433.10 RJW71762.1 - 0.04 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 RJW71762.1 - 0.093 13.0 0.0 0.35 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 RJW71762.1 - 0.13 11.4 0.0 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Arrestin_N PF00339.29 RJW71763.1 - 4.5e-33 114.4 0.1 3.4e-14 53.1 0.0 3.4 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RJW71763.1 - 3.6e-23 82.5 0.2 1.3e-22 80.7 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Cas_APE2256 PF09651.10 RJW71764.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) Paramyxo_P PF01806.17 RJW71764.1 - 0.053 13.0 0.9 0.087 12.3 0.9 1.3 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region EF_assoc_2 PF08356.12 RJW71766.1 - 4.1e-34 116.4 0.0 1.9e-33 114.3 0.0 2.1 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 RJW71766.1 - 8.5e-18 64.5 0.0 1.1e-12 47.9 0.0 2.9 2 1 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 RJW71766.1 - 2.2e-14 52.8 0.0 8e-14 51.0 0.0 2.1 2 0 0 2 2 2 1 EF hand associated EF-hand_7 PF13499.6 RJW71766.1 - 1e-12 48.3 0.0 6e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW71766.1 - 6e-10 38.0 0.1 0.00046 19.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW71766.1 - 4.3e-09 35.6 0.1 0.0024 17.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain Roc PF08477.13 RJW71766.1 - 1.3e-07 31.9 0.0 6.6e-05 23.1 0.0 2.6 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_5 PF13202.6 RJW71766.1 - 1.7e-07 30.4 0.0 0.0079 15.6 0.0 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 RJW71766.1 - 0.00012 22.4 0.0 0.87 9.9 0.0 2.9 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 RJW71766.1 - 0.0014 18.4 0.1 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 RJW71766.1 - 0.004 17.0 0.2 0.043 13.7 0.1 2.2 2 0 0 2 2 2 1 EF hand AAA_14 PF13173.6 RJW71766.1 - 0.011 15.8 0.5 3.8 7.6 0.5 2.4 2 0 0 2 2 2 0 AAA domain IMS PF00817.20 RJW71767.1 - 1.4e-24 86.8 0.0 2.4e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 RJW71767.1 - 1.2e-11 44.0 0.2 2.2e-11 43.1 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 RJW71767.1 - 2.4e-07 31.4 0.0 8.8e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF3337 PF11816.8 RJW71769.1 - 3.6e-28 98.6 0.0 3.2e-15 56.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.32 RJW71769.1 - 2.8e-24 84.9 7.8 1.1e-05 26.1 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW71769.1 - 1.1e-07 32.0 1.3 0.26 11.6 0.0 4.7 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW71769.1 - 0.013 14.2 5.9 2 6.9 0.0 3.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RJW71769.1 - 0.015 14.3 0.1 6.7 5.6 0.0 2.8 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RAWUL PF16207.5 RJW71769.1 - 0.098 13.3 0.0 0.25 12.0 0.0 1.7 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Spc7 PF08317.11 RJW71770.1 - 0.0034 16.3 18.9 0.0034 16.3 18.9 3.6 2 2 1 3 3 3 1 Spc7 kinetochore protein OrfB_IS605 PF01385.19 RJW71770.1 - 0.012 15.8 0.0 0.012 15.8 0.0 4.9 3 1 1 5 5 5 0 Probable transposase Rep_fac-A_3 PF08661.11 RJW71770.1 - 0.17 12.2 3.4 0.15 12.4 0.7 2.2 2 0 0 2 2 2 0 Replication factor A protein 3 CENP-F_leu_zip PF10473.9 RJW71770.1 - 0.24 11.4 50.0 0.74 9.8 13.8 4.5 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps51 PF08700.11 RJW71770.1 - 0.29 11.2 0.1 0.29 11.2 0.1 4.2 3 2 1 4 4 4 0 Vps51/Vps67 DUF2740 PF10872.8 RJW71770.1 - 5.7 6.9 7.9 2.5 8.0 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2740) KH_6 PF15985.5 RJW71771.1 - 2e-09 37.7 0.2 6.2e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 KH domain ECR1_N PF14382.6 RJW71771.1 - 0.0015 18.3 0.4 0.0061 16.3 0.4 2.1 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Ribosomal_L5e PF17144.4 RJW71772.1 - 2.6e-86 287.7 0.8 2.6e-86 287.7 0.8 1.5 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 RJW71772.1 - 5.2e-33 113.9 1.3 1.2e-32 112.7 1.3 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Cyt-b5 PF00173.28 RJW71773.1 - 2.3e-17 62.9 0.7 1.1e-16 60.8 0.3 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_kinase PF01513.21 RJW71774.1 - 1.1e-36 126.6 0.0 1.3e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Forkhead PF00250.18 RJW71775.1 - 1.7e-20 73.1 0.1 4.8e-20 71.6 0.1 1.8 1 0 0 1 1 1 1 Forkhead domain PAP_central PF04928.17 RJW71776.1 - 0.049 12.6 0.6 0.09 11.7 0.6 1.4 1 0 0 1 1 1 0 Poly(A) polymerase central domain zf-C2H2 PF00096.26 RJW71777.1 - 9.2e-08 32.1 12.4 0.00072 19.9 1.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW71777.1 - 1.3e-07 31.8 12.0 0.002 18.8 1.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 RJW71777.1 - 0.00037 20.8 9.6 0.056 13.9 0.8 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW71777.1 - 0.003 17.8 9.3 0.083 13.2 0.5 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RJW71777.1 - 0.0039 16.9 11.1 0.019 14.7 3.3 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 RJW71777.1 - 0.016 15.6 9.0 2 9.0 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double domain DUF629 PF04780.12 RJW71777.1 - 0.024 13.2 1.2 1.7 7.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 RJW71777.1 - 0.067 13.5 4.9 3 8.2 0.3 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.13 RJW71777.1 - 0.18 12.2 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 zf-BED PF02892.15 RJW71777.1 - 0.21 11.7 8.3 1.2 9.3 2.3 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 RJW71777.1 - 0.39 11.4 4.1 2.6 8.7 0.5 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 RJW71777.1 - 2.3 8.3 8.7 3.1 7.9 1.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger CDC37_M PF08565.11 RJW71778.1 - 0.012 15.5 0.1 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Cdc37 Hsp90 binding domain PhoLip_ATPase_C PF16212.5 RJW71779.1 - 1.4e-48 165.8 22.4 1.4e-48 165.8 22.4 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RJW71779.1 - 1.5e-17 63.0 1.1 3.7e-17 61.8 1.1 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RJW71779.1 - 4.4e-15 56.5 0.7 6.3e-07 29.9 1.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RJW71779.1 - 1.1e-13 51.1 0.8 5.8e-13 48.8 0.0 2.7 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 RJW71779.1 - 2e-09 37.4 0.0 1.8e-08 34.3 0.0 2.5 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RJW71779.1 - 0.0082 15.9 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_MLP1_2 PF07926.12 RJW71781.1 - 1.8e-11 44.2 17.4 1.8e-11 44.2 17.4 12.5 6 3 6 12 12 12 9 TPR/MLP1/MLP2-like protein MbeD_MobD PF04899.12 RJW71781.1 - 0.017 15.3 0.6 0.017 15.3 0.6 8.8 8 4 2 10 10 10 0 MbeD/MobD like VPS53_C PF16854.5 RJW71781.1 - 0.14 12.0 1.0 0.6 9.9 1.0 2.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus MBOAT PF03062.19 RJW71783.1 - 1.6e-21 77.0 8.7 1.6e-21 77.0 8.7 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family TMIE PF16038.5 RJW71783.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 TMIE protein DUF1925 PF09094.11 RJW71783.1 - 0.047 14.0 1.1 0.28 11.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) gag-asp_proteas PF13975.6 RJW71784.1 - 1.4e-05 25.6 0.0 2.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RJW71784.1 - 5.7e-05 23.7 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_4 PF14392.6 RJW71784.1 - 0.69 9.7 4.0 1.6 8.5 4.0 1.6 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.22 RJW71786.1 - 2.8e-23 81.5 0.1 4.5e-15 55.2 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW71786.1 - 0.0033 17.0 0.1 0.32 10.6 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RJW71786.1 - 0.016 15.3 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif zf-RanBP PF00641.18 RJW71787.1 - 1.2e-07 30.9 6.0 1.7e-07 30.4 6.0 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Rubredoxin_2 PF18073.1 RJW71787.1 - 3.2 7.5 8.0 5 6.9 8.0 1.3 1 0 0 1 1 1 0 Rubredoxin metal binding domain Cript PF10235.9 RJW71793.1 - 2.2e-32 111.5 4.4 2.2e-32 111.5 4.4 1.5 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 RJW71793.1 - 0.00052 20.3 8.7 0.00087 19.6 5.4 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Gin PF10764.9 RJW71793.1 - 0.023 14.6 6.9 1.1 9.2 0.1 3.1 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin DZR PF12773.7 RJW71793.1 - 0.096 12.7 12.9 13 5.9 12.9 2.7 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 RJW71793.1 - 0.3 11.9 14.1 7.9 7.3 7.9 2.7 2 1 0 2 2 2 0 zinc-ribbon family C1_2 PF03107.16 RJW71793.1 - 0.5 10.7 13.6 0.25 11.7 7.9 2.7 2 1 1 3 3 3 0 C1 domain zinc-ribbons_6 PF07191.12 RJW71793.1 - 1.6 8.8 12.1 5.4 7.1 7.9 2.4 2 1 0 2 2 2 0 zinc-ribbons CEBP_ZZ PF16366.5 RJW71793.1 - 2.3 8.5 12.4 3.4 8.0 9.4 2.5 2 1 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zinc_ribbon_2 PF13240.6 RJW71793.1 - 3.3 7.5 12.9 3.9 7.3 0.1 3.6 3 1 0 3 3 3 0 zinc-ribbon domain ADK_lid PF05191.14 RJW71793.1 - 4 7.5 7.2 23 5.1 2.0 3.2 2 1 0 2 2 2 0 Adenylate kinase, active site lid Hydrolase_6 PF13344.6 RJW71794.1 - 1.1e-25 89.7 0.0 2.7e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RJW71794.1 - 1.3e-19 70.0 0.0 2.2e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 RJW71794.1 - 6e-09 36.2 0.3 3.2e-05 24.1 0.0 3.7 3 1 1 4 4 4 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RJW71794.1 - 1.5e-05 25.4 0.0 0.00016 22.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 RJW71794.1 - 0.00029 20.5 0.1 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase 7tm_1 PF00001.21 RJW71795.1 - 8.3e-09 35.1 18.8 1.1e-08 34.7 18.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MCM_lid PF17855.1 RJW71797.1 - 0.095 13.1 0.3 0.2 12.1 0.3 1.5 1 0 0 1 1 1 0 MCM AAA-lid domain DC_STAMP PF07782.13 RJW71798.1 - 9e-36 123.5 1.4 3.6e-35 121.5 0.1 2.7 3 0 0 3 3 3 1 DC-STAMP-like protein Tetraspanin PF00335.20 RJW71798.1 - 1.1e-10 41.6 0.9 1.1e-10 41.6 0.9 2.4 3 0 0 3 3 3 1 Tetraspanin family RasGAP_C PF03836.15 RJW71798.1 - 0.012 15.8 1.8 0.059 13.5 1.8 2.2 1 0 0 1 1 1 0 RasGAP C-terminus zf-C3HC4_3 PF13920.6 RJW71798.1 - 0.051 13.4 4.9 0.15 11.9 4.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PRESAN PF09687.10 RJW71798.1 - 0.12 12.9 2.4 0.34 11.5 2.4 1.7 1 0 0 1 1 1 0 Plasmodium RESA N-terminal XRN_M PF17846.1 RJW71799.1 - 3.1e-74 250.5 0.1 2e-73 247.9 0.1 2.0 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 RJW71799.1 - 9.1e-61 205.4 0.0 1.5e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 RJW71799.1 - 1.4e-09 38.0 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain zf-C2H2 PF00096.26 RJW71800.1 - 7.3e-14 51.4 31.8 0.00065 20.0 4.3 4.6 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW71800.1 - 4.9e-10 39.4 27.7 0.0059 17.4 0.4 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 RJW71800.1 - 1e-05 25.8 21.8 0.029 14.7 0.5 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RJW71800.1 - 0.00028 20.6 30.9 0.35 10.7 0.8 4.3 4 0 0 4 4 4 4 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RJW71800.1 - 0.00047 20.1 21.4 0.017 15.1 0.2 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 RJW71800.1 - 0.00087 20.0 7.1 0.033 14.9 1.2 2.5 2 2 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 RJW71800.1 - 0.0011 19.3 0.2 0.0011 19.3 0.2 4.9 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 RJW71800.1 - 0.0016 18.7 7.0 0.013 15.7 1.5 2.7 2 1 0 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 RJW71800.1 - 0.0091 16.3 15.8 8.4 6.8 0.3 4.4 3 1 1 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 RJW71800.1 - 0.068 13.0 6.3 1.5 8.7 0.2 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 RJW71800.1 - 0.3 11.2 17.1 0.73 10.0 4.1 3.4 2 2 0 2 2 2 0 FYVE zinc finger zf_C2H2_ZHX PF18387.1 RJW71800.1 - 3.4 7.4 15.4 7 6.4 0.8 4.1 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF629 PF04780.12 RJW71800.1 - 4.3 5.7 12.8 7.7 4.9 0.2 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF629) Sua5_yciO_yrdC PF01300.18 RJW71803.1 - 6.9e-40 136.5 0.0 1e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination Pkinase PF00069.25 RJW71804.1 - 6.2e-51 173.3 0.0 7.2e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW71804.1 - 1.8e-21 76.6 0.0 2.2e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW71804.1 - 0.0054 15.7 0.0 0.0074 15.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RJW71804.1 - 0.015 14.6 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RJW71804.1 - 0.017 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW71804.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 RJW71804.1 - 0.031 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family zf-SNAP50_C PF12251.8 RJW71805.1 - 3.7e-59 199.8 1.2 5.1e-59 199.3 1.2 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF1712 PF08217.11 RJW71806.1 - 7.8e-26 90.7 0.7 2e-24 86.0 0.3 2.7 3 1 0 3 3 3 2 Fungal domain of unknown function (DUF1712) Surfac_D-trimer PF09006.11 RJW71806.1 - 0.15 12.0 0.2 7.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DnaJ PF00226.31 RJW71807.1 - 8e-19 67.5 0.1 1.5e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain RCC1 PF00415.18 RJW71808.1 - 2.2e-34 117.8 20.6 1.5e-06 28.7 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RJW71808.1 - 7.4e-16 57.5 33.0 0.00013 21.7 0.4 7.7 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat LRR_8 PF13855.6 RJW71809.1 - 5.9e-10 38.8 12.8 4.7e-05 23.1 5.3 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RJW71809.1 - 0.00022 21.5 24.7 0.0072 16.7 0.5 5.0 4 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW71809.1 - 0.048 14.2 23.6 1.1 10.0 0.1 6.6 5 2 1 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 RJW71809.1 - 0.16 12.1 19.6 2.2 8.6 0.1 6.0 6 0 0 6 6 6 0 Leucine Rich repeat Syndecan PF01034.20 RJW71810.1 - 0.16 11.9 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain WW PF00397.26 RJW71811.1 - 3.2e-05 23.9 0.5 0.00015 21.7 0.2 2.4 2 0 0 2 2 2 1 WW domain Kelch_1 PF01344.25 RJW71812.1 - 1.5e-66 219.7 12.7 6.6e-12 44.8 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RJW71812.1 - 1.2e-41 139.6 4.7 5e-06 26.6 0.0 6.9 4 3 3 7 7 7 6 Kelch motif BTB PF00651.31 RJW71812.1 - 4.8e-32 110.5 0.1 1.3e-31 109.1 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 RJW71812.1 - 1e-29 102.7 1.5 2.1e-29 101.7 1.5 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 RJW71812.1 - 4.1e-23 80.4 7.2 0.0013 18.6 0.0 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 RJW71812.1 - 5.3e-23 80.8 4.0 0.00079 19.4 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 RJW71812.1 - 2.9e-19 68.9 8.8 0.023 15.0 0.1 7.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW71812.1 - 7.9e-10 38.5 11.8 0.93 9.5 0.0 6.6 6 0 0 6 6 6 5 Kelch motif DUF3342 PF11822.8 RJW71812.1 - 0.001 19.2 0.1 0.13 12.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) JAB PF01398.21 RJW71813.1 - 2.8e-18 66.0 0.3 4.3e-18 65.4 0.3 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RJW71813.1 - 5.6e-15 55.7 0.5 1.2e-14 54.7 0.5 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function SARAF PF06682.12 RJW71815.1 - 3e-55 188.2 0.2 8e-55 186.8 0.2 1.7 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF2076 PF09849.9 RJW71815.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Adaptin_N PF01602.20 RJW71816.1 - 5.5e-99 332.1 3.6 7e-99 331.8 3.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 RJW71816.1 - 2.5e-54 183.5 0.1 5.5e-54 182.4 0.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 RJW71816.1 - 4.8e-26 91.1 0.0 1.6e-25 89.5 0.0 2.0 1 1 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 RJW71816.1 - 8.5e-13 48.5 3.5 0.00068 20.0 0.0 5.4 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.7 RJW71816.1 - 1.3e-08 35.1 6.9 0.00088 19.3 0.7 4.4 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RJW71816.1 - 2.1e-05 24.4 2.8 0.45 10.9 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 RJW71816.1 - 0.0046 17.4 5.3 1.5 9.4 0.5 3.8 2 2 1 3 3 3 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 RJW71816.1 - 0.12 13.0 2.3 6.8 7.4 0.1 3.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Nfu_N PF08712.11 RJW71817.1 - 1.2e-32 111.8 0.0 2.1e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 RJW71817.1 - 6.2e-27 93.5 0.1 9.6e-27 92.9 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Mito_carr PF00153.27 RJW71818.1 - 3e-31 107.2 0.7 3.4e-11 42.9 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Metallopep PF12044.8 RJW71819.1 - 5.2e-53 180.2 0.0 7.8e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M10 PF00413.24 RJW71819.1 - 0.016 15.1 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 RJW71819.1 - 0.026 13.5 0.5 0.046 12.7 0.5 1.3 1 0 0 1 1 1 0 Peptidase M66 Tat PF00539.18 RJW71819.1 - 0.091 12.9 2.5 0.22 11.7 2.5 1.6 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) Reprolysin_3 PF13582.6 RJW71819.1 - 0.11 13.0 0.2 0.19 12.3 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like zf-H2C2_5 PF13909.6 RJW71820.1 - 2.6e-10 39.8 49.3 6.9e-07 28.9 0.6 8.3 8 0 0 8 8 8 4 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RJW71820.1 - 0.00014 22.2 0.2 0.00014 22.2 0.2 9.7 12 0 0 12 12 12 1 Zinc-finger double domain Sina PF03145.16 RJW71820.1 - 0.066 13.2 0.2 0.066 13.2 0.2 4.3 3 1 1 4 4 4 0 Seven in absentia protein family zf-C2H2 PF00096.26 RJW71820.1 - 0.12 12.9 68.4 0.046 14.2 5.6 8.8 8 0 0 8 8 8 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW71820.1 - 0.16 12.8 71.4 0.2 12.6 1.5 8.7 8 0 0 8 8 8 0 C2H2-type zinc finger AKAP95 PF04988.12 RJW71820.1 - 1.6 8.9 28.0 0.12 12.6 1.2 5.8 4 1 1 5 5 5 0 A-kinase anchoring protein 95 (AKAP95) Glyco_transf_8 PF01501.20 RJW71821.1 - 0.00011 21.9 0.3 0.00028 20.5 0.3 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 RJW71821.1 - 0.013 14.9 0.3 0.024 14.1 0.3 1.4 1 0 0 1 1 1 0 Glucosyltransferase 24 PLAC8 PF04749.17 RJW71822.1 - 8.2e-12 46.0 12.4 1.1e-11 45.5 12.4 1.2 1 0 0 1 1 1 1 PLAC8 family DUF5463 PF17551.2 RJW71822.1 - 0.016 15.1 1.3 0.016 15.1 1.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5463) ORC3_N PF07034.11 RJW71823.1 - 1.6e-22 80.0 0.0 2.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 RJW71823.1 - 8e-14 51.9 0.0 1.5e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal RMI1_N PF08585.12 RJW71824.1 - 0.11 12.3 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 RecQ mediated genome instability protein Pkinase PF00069.25 RJW71825.1 - 6.2e-53 179.9 0.0 8.7e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW71825.1 - 1.7e-17 63.6 0.0 2.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RJW71825.1 - 0.0023 17.3 0.0 0.0059 16.0 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RJW71825.1 - 0.0025 17.2 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RJW71825.1 - 0.012 14.4 0.3 0.054 12.3 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 RJW71825.1 - 0.052 13.5 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 RJW71825.1 - 0.068 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 RJW71825.1 - 0.11 11.4 0.0 0.26 10.2 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain 7tm_1 PF00001.21 RJW71826.1 - 4.4e-11 42.6 18.7 7.5e-11 41.8 18.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SH3_9 PF14604.6 RJW71827.1 - 2.1e-10 40.3 0.2 4.5e-10 39.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RJW71827.1 - 1.1e-07 31.4 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RJW71827.1 - 2.7e-06 26.9 0.0 5.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Tubulin PF00091.25 RJW71828.1 - 1.4e-69 234.3 0.0 2.3e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW71828.1 - 1e-43 148.5 0.1 1.6e-43 147.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RJW71828.1 - 1.1e-05 25.7 0.0 2.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RJW71828.1 - 0.0066 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RJW71828.1 - 0.015 14.5 0.1 0.033 13.4 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Pro_isomerase PF00160.21 RJW71829.1 - 4.3e-37 127.8 0.2 1.5e-36 126.0 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3606 PF12244.8 RJW71830.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) 2OG-FeII_Oxy_3 PF13640.6 RJW71831.1 - 5.2e-17 62.5 0.0 1e-16 61.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RJW71831.1 - 3.6e-11 43.6 0.0 8.9e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CID_GANP PF16766.5 RJW71831.1 - 0.03 14.5 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Binding region of GANP to ENY2 MBOAT PF03062.19 RJW71832.1 - 6.5e-08 32.3 30.4 2.2e-07 30.6 11.6 3.2 2 2 1 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family DPM3 PF08285.11 RJW71832.1 - 0.018 15.2 0.8 0.018 15.2 0.8 3.0 4 0 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) gag-asp_proteas PF13975.6 RJW71835.1 - 1.5e-05 25.5 0.0 2.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RJW71835.1 - 5.8e-05 23.6 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_4 PF14392.6 RJW71835.1 - 0.7 9.7 4.0 1.6 8.5 4.0 1.6 1 0 0 1 1 1 0 Zinc knuckle ABATE PF07336.11 RJW71840.1 - 0.034 14.8 0.1 0.042 14.5 0.1 1.2 1 0 0 1 1 1 0 Putative stress-induced transcription regulator Arf PF00025.21 RJW71841.1 - 7.8e-41 139.4 0.0 1.2e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RJW71841.1 - 2.2e-11 44.0 0.0 3.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RJW71841.1 - 1.6e-10 40.7 0.1 8.3e-07 28.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 RJW71841.1 - 3.3e-10 39.8 0.0 4.8e-10 39.3 0.0 1.3 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RJW71841.1 - 1.4e-07 31.1 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RJW71841.1 - 1.2e-05 24.8 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RJW71841.1 - 2.8e-05 24.2 0.0 6.6e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 RJW71841.1 - 0.026 14.2 0.0 1.5 8.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain Phage_B PF02304.15 RJW71842.1 - 0.069 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Scaffold protein B TPR_1 PF00515.28 RJW71843.1 - 9e-17 60.1 21.5 2.8e-05 23.7 1.9 8.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 RJW71843.1 - 1.7e-15 55.8 18.8 6.8e-05 22.7 0.4 8.1 9 1 1 10 10 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 RJW71843.1 - 1.6e-12 47.5 15.0 0.00063 20.0 0.3 6.4 5 1 3 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 RJW71843.1 - 5.2e-12 45.0 12.1 0.005 16.9 0.4 6.9 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 RJW71843.1 - 1.6e-08 34.1 7.5 0.32 10.7 0.1 7.3 5 1 3 8 8 8 2 TPR repeat TPR_14 PF13428.6 RJW71843.1 - 6e-08 32.9 4.3 0.16 12.9 0.5 6.4 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW71843.1 - 7.5e-07 29.7 5.5 0.27 11.9 0.0 4.4 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 RJW71843.1 - 7.5e-06 26.0 10.5 0.26 11.8 0.0 6.7 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 RJW71843.1 - 7.7e-06 25.6 8.9 0.00025 20.8 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW71843.1 - 5.7e-05 23.2 0.8 0.0048 17.0 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW71843.1 - 0.0039 17.1 10.3 37 4.7 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF5112 PF17139.4 RJW71843.1 - 0.0071 15.9 10.7 0.19 11.2 0.9 3.4 3 2 0 3 3 3 2 Domain of unknown function (DUF5112) TPR_15 PF13429.6 RJW71843.1 - 0.012 14.8 0.7 0.44 9.7 0.1 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW71843.1 - 0.021 15.4 6.2 8.5 7.3 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW71843.1 - 0.022 15.0 13.1 0.47 10.7 4.9 4.7 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RJW71843.1 - 0.043 14.3 12.9 1.4 9.4 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 RJW71843.1 - 0.061 13.6 0.0 1.5 9.2 0.0 3.2 3 0 0 3 3 3 0 PPR repeat MIT PF04212.18 RJW71843.1 - 0.15 12.1 1.5 6.8 6.8 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Fumerase_C PF05683.12 RJW71845.1 - 1.4e-89 298.8 0.0 2.4e-89 298.1 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 RJW71845.1 - 2.7e-85 286.1 0.0 3.7e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Colipase_C PF02740.14 RJW71845.1 - 0.16 12.2 0.1 0.4 10.9 0.1 1.6 1 0 0 1 1 1 0 Colipase, C-terminal domain CTK3 PF12243.8 RJW71846.1 - 0.16 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 PB1 PF00564.24 RJW71847.1 - 6.7e-13 48.4 0.6 7.6e-13 48.2 0.6 1.1 1 0 0 1 1 1 1 PB1 domain Peptidase_M1_N PF17900.1 RJW71847.1 - 0.051 13.7 0.0 0.053 13.7 0.0 1.0 1 0 0 1 1 1 0 Peptidase M1 N-terminal domain zf-C2H2 PF00096.26 RJW71848.1 - 0.0025 18.2 6.4 0.0025 18.2 6.4 5.7 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RJW71848.1 - 0.0045 16.7 6.1 0.0045 16.7 6.1 2.9 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RJW71848.1 - 0.13 12.8 14.4 0.55 10.8 0.4 4.4 4 0 0 4 4 4 0 Zinc-finger double domain DUF684 PF05075.14 RJW71848.1 - 0.87 8.5 2.1 1.4 7.8 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF684) zf-BED PF02892.15 RJW71848.1 - 1.6 8.8 10.7 0.2 11.7 1.7 3.0 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 RJW71848.1 - 2.1 8.8 7.2 4.2 7.8 1.3 3.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RVT_1 PF00078.27 RJW71849.1 - 2.8e-41 141.5 0.0 7.8e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW71849.1 - 4e-07 29.9 0.0 9.5e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SNAP PF14938.6 RJW71853.1 - 2.3e-16 60.1 7.0 1.8e-15 57.2 4.7 2.0 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 RJW71853.1 - 0.00035 20.4 11.3 0.27 11.3 0.2 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TOM20_plant PF06552.12 RJW71853.1 - 0.0021 17.8 1.0 0.0099 15.6 0.2 2.1 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 Sel1 PF08238.12 RJW71853.1 - 0.0061 17.2 2.4 0.38 11.5 0.0 3.2 3 0 0 3 3 2 1 Sel1 repeat TPR_MalT PF17874.1 RJW71853.1 - 0.02 14.3 5.3 0.071 12.5 5.2 1.8 1 1 0 1 1 1 0 MalT-like TPR region TPR_16 PF13432.6 RJW71853.1 - 0.049 14.3 13.7 2.3 9.0 0.0 5.3 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RJW71853.1 - 0.065 13.5 17.3 0.48 10.7 0.7 4.4 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 RJW71853.1 - 0.093 13.0 10.5 2.8 8.4 1.8 4.6 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW71853.1 - 0.48 11.2 4.4 19 6.2 0.7 4.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RJW71853.1 - 0.6 10.1 5.6 1.5 8.8 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RJW71853.1 - 3.7 8.6 14.7 24 6.1 0.3 5.8 2 1 3 6 6 6 0 Tetratricopeptide repeat MT PF12777.7 RJW71854.1 - 8.6e-168 557.7 12.3 8.6e-168 557.7 12.3 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 RJW71854.1 - 8.1e-154 511.4 0.0 1.2e-150 501.0 0.0 3.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW71854.1 - 3.9e-121 404.9 18.0 3.9e-121 404.9 18.0 5.4 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RJW71854.1 - 4e-98 327.9 0.0 1.3e-97 326.2 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RJW71854.1 - 6.5e-97 324.5 3.0 1e-96 323.8 0.1 2.8 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RJW71854.1 - 7.8e-86 286.7 0.6 7.8e-86 286.7 0.6 2.5 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 RJW71854.1 - 1.7e-75 252.5 0.0 6.3e-69 231.1 0.0 4.1 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RJW71854.1 - 2.9e-55 186.5 0.0 8.6e-55 185.0 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RJW71854.1 - 8.5e-40 135.6 0.0 3.1e-37 127.3 0.0 3.7 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 RJW71854.1 - 1.3e-38 131.3 3.0 3.4e-38 129.9 0.4 3.1 2 0 0 2 2 2 1 AAA+ lid domain DHC_N1 PF08385.12 RJW71854.1 - 7.6e-34 117.3 0.9 7.6e-34 117.3 0.9 4.5 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 Dynein_AAA_lid PF17852.1 RJW71854.1 - 3e-27 95.2 0.1 1.3e-26 93.2 0.1 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RJW71854.1 - 5.1e-24 84.8 0.0 1.1e-10 41.6 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RJW71854.1 - 5e-07 30.1 1.5 1.6 9.0 0.0 5.4 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 RJW71854.1 - 1.4e-06 28.8 2.3 0.14 12.6 0.0 5.5 4 1 1 5 5 4 2 AAA ATPase domain AAA PF00004.29 RJW71854.1 - 4.5e-06 27.1 0.2 0.83 10.1 0.0 6.1 6 0 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RJW71854.1 - 8.6e-05 22.3 0.0 0.25 11.1 0.0 3.5 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_30 PF13604.6 RJW71854.1 - 0.00031 20.5 1.1 4.9 6.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 RJW71854.1 - 0.00037 20.5 0.0 0.11 12.5 0.0 3.9 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 RJW71854.1 - 0.0031 17.5 0.3 0.54 10.3 0.0 3.3 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 RJW71854.1 - 0.0044 16.3 0.1 0.17 11.0 0.0 3.2 3 0 0 3 3 3 1 PIF1-like helicase DUF2075 PF09848.9 RJW71854.1 - 0.0045 16.3 1.0 1.1 8.4 0.0 3.0 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 RJW71854.1 - 0.0055 15.8 0.0 0.34 9.9 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_24 PF13479.6 RJW71854.1 - 0.0057 16.4 0.1 3.8 7.2 0.0 4.0 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 RJW71854.1 - 0.014 15.5 0.0 8.1 6.6 0.0 3.5 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 RJW71854.1 - 0.02 14.3 0.2 13 5.2 0.0 3.7 3 0 0 3 3 3 0 PhoH-like protein Mg_chelatase PF01078.21 RJW71854.1 - 0.029 13.7 0.6 2 7.8 0.0 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI BORCS6 PF10157.9 RJW71854.1 - 0.029 14.6 0.1 0.029 14.6 0.1 2.6 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 RNA_helicase PF00910.22 RJW71854.1 - 0.037 14.4 0.0 86 3.6 0.0 4.0 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 RJW71854.1 - 0.06 13.9 6.0 2.2 8.8 0.0 5.2 7 0 0 7 7 3 0 AAA domain TatD_DNase PF01026.21 RJW71854.1 - 0.088 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 TatD related DNase AAA_19 PF13245.6 RJW71854.1 - 0.12 12.8 7.3 14 6.0 0.0 5.0 5 0 0 5 5 4 0 AAA domain zf-C4H2 PF10146.9 RJW71854.1 - 1.7 8.9 18.9 0.79 10.0 4.0 4.6 4 0 0 4 4 3 0 Zinc finger-containing protein ATG16 PF08614.11 RJW71854.1 - 2.1 8.5 22.9 9.4 6.4 8.8 3.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 RJW71854.1 - 7.7 7.1 13.7 9.8 6.7 0.2 5.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein RNA_pol PF00940.19 RJW71855.1 - 4.1e-153 510.1 0.0 6.4e-153 509.5 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 RJW71855.1 - 4.2e-24 85.6 0.0 8e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal KIP1 PF07765.12 RJW71855.1 - 0.17 12.0 0.4 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 KIP1-like protein Vac14_Fig4_bd PF11916.8 RJW71856.1 - 4.5e-62 208.9 4.0 9e-62 207.9 4.0 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 RJW71856.1 - 7.4e-35 119.4 0.0 2e-31 108.4 0.0 3.6 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 RJW71856.1 - 6.2e-12 44.7 3.9 0.0037 17.4 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 RJW71856.1 - 7.1e-08 32.8 0.6 0.54 10.8 0.0 5.1 4 1 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 RJW71856.1 - 1.2e-06 28.8 0.2 0.17 12.3 0.0 4.1 2 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 RJW71856.1 - 7.3e-06 26.1 0.1 0.62 10.1 0.0 4.1 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RJW71856.1 - 0.00027 19.6 0.0 0.015 13.9 0.0 2.5 2 1 1 3 3 3 1 Adaptin N terminal region Tti2 PF10521.9 RJW71856.1 - 0.00031 20.4 0.5 0.23 11.0 0.0 3.5 3 0 0 3 3 3 1 Tti2 family RTP1_C1 PF10363.9 RJW71856.1 - 0.00031 20.9 0.1 0.038 14.2 0.0 3.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 RJW71856.1 - 0.00045 19.8 0.1 0.63 9.6 0.0 3.9 3 0 0 3 3 3 1 CLASP N terminal Arm PF00514.23 RJW71856.1 - 0.005 16.8 0.0 3.4 7.9 0.3 3.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 RJW71856.1 - 0.01 16.2 0.5 0.46 10.9 0.1 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cohesin_HEAT PF12765.7 RJW71856.1 - 0.019 15.2 0.1 0.21 11.9 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion PTPLA PF04387.14 RJW71857.1 - 7.4e-42 142.9 11.3 8.9e-42 142.6 11.3 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA La PF05383.17 RJW71858.1 - 1.7e-10 40.8 0.0 1.2e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 La domain Piwi PF02171.17 RJW71859.1 - 2.2e-81 273.4 0.0 4.3e-81 272.5 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RJW71859.1 - 1.6e-10 40.9 0.2 3.1e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 RJW71859.1 - 4e-08 33.5 0.0 8.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoN PF16486.5 RJW71859.1 - 2.9e-06 28.0 0.0 9.2e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ING PF12998.7 RJW71861.1 - 1.2e-18 67.5 7.0 1.2e-18 67.5 7.0 1.8 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Swi5 PF07061.11 RJW71861.1 - 1.5e-12 47.4 0.1 1.5e-12 47.4 0.1 3.1 2 1 0 2 2 2 1 Swi5 PHD PF00628.29 RJW71861.1 - 2.1e-06 27.5 9.2 3.6e-06 26.8 9.2 1.4 1 0 0 1 1 1 1 PHD-finger PaaA_PaaC PF05138.12 RJW71861.1 - 0.037 13.2 1.0 0.06 12.5 1.0 1.3 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein zf-C4H2 PF10146.9 RJW71861.1 - 0.079 13.3 10.8 0.059 13.7 9.4 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein Sec2p PF06428.11 RJW71861.1 - 0.18 11.8 14.0 5.3 7.1 0.1 3.2 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p zf-C4pol PF14260.6 RJW71861.1 - 0.23 12.0 9.7 0.25 11.9 1.4 3.3 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta ubiquitin PF00240.23 RJW71861.1 - 1.5 8.6 4.5 5.3 6.9 0.2 2.8 3 0 0 3 3 3 0 Ubiquitin family Spc7 PF08317.11 RJW71861.1 - 1.8 7.4 18.3 0.18 10.6 12.0 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Phage_GPO PF05929.11 RJW71861.1 - 2.2 7.8 8.8 1.3 8.6 6.5 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-RING-like PF08746.11 RJW71861.1 - 2.9 8.3 7.1 5.9 7.3 7.1 1.6 1 0 0 1 1 1 0 RING-like domain DUF1664 PF07889.12 RJW71861.1 - 3.1 7.8 7.5 2.7 8.1 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 RJW71861.1 - 4.2 8.2 13.0 8.8 7.1 0.1 3.1 2 1 1 3 3 3 0 Occludin homology domain RVT_1 PF00078.27 RJW71862.1 - 4.4e-05 23.1 0.0 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lipoprotein_7 PF01540.16 RJW71862.1 - 0.0075 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein BLOC1_2 PF10046.9 RJW71862.1 - 0.094 13.0 3.0 0.18 12.1 3.0 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 RJW71862.1 - 0.25 11.6 3.6 0.31 11.3 2.5 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 RJW71862.1 - 0.35 11.1 7.1 0.69 10.1 7.1 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 STAT_alpha PF01017.20 RJW71862.1 - 0.72 9.7 5.8 3.3 7.6 3.5 2.3 1 1 1 2 2 2 0 STAT protein, all-alpha domain Spc24 PF08286.11 RJW71862.1 - 0.82 9.9 2.5 7 7.0 0.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 RJW71862.1 - 0.88 8.4 5.1 1.4 7.7 5.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 RJW71862.1 - 1.7 8.9 12.0 23 5.2 12.0 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 RJW71862.1 - 1.9 7.6 13.2 4.9 6.3 13.2 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF5595 PF18077.1 RJW71862.1 - 4.7 7.4 5.7 0.37 10.9 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Csm1_N PF18504.1 RJW71862.1 - 7 7.1 9.6 3.8 7.9 1.6 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain RRM_1 PF00076.22 RJW71866.1 - 6.8e-14 51.4 0.0 1.3e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW71866.1 - 2.3e-06 27.2 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3791 PF12668.7 RJW71866.1 - 0.042 13.9 0.2 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) DC_STAMP PF07782.13 RJW71867.1 - 1e-30 107.0 1.4 2.7e-30 105.6 1.4 1.8 1 0 0 1 1 1 1 DC-STAMP-like protein Tetraspanin PF00335.20 RJW71867.1 - 2.1e-11 44.0 0.8 2.1e-11 44.0 0.8 2.2 2 0 0 2 2 2 1 Tetraspanin family Osmo_MPGsynth PF09488.10 RJW71867.1 - 0.16 10.6 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Ribonuc_P_40 PF08584.11 RJW71870.1 - 2.3e-06 27.1 0.0 3.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit PNP_phzG_C PF10590.9 RJW71870.1 - 0.3 11.2 1.5 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region WD40 PF00400.32 RJW71871.1 - 0.00044 21.0 0.5 2.7 9.0 0.0 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat HAND PF09110.11 RJW71871.1 - 4.4 8.1 8.4 0.085 13.6 0.8 2.1 2 0 0 2 2 2 0 HAND Stevor PF17410.2 RJW71872.1 - 0.0032 17.1 0.5 0.0032 17.1 0.5 1.8 1 1 1 2 2 2 1 Subtelomeric Variable Open Reading frame PalH PF08733.10 RJW71872.1 - 0.0074 15.3 5.5 0.011 14.8 5.5 1.3 1 0 0 1 1 1 1 PalH/RIM21 TspO_MBR PF03073.15 RJW71872.1 - 0.017 15.2 5.1 0.034 14.2 5.0 1.6 1 1 0 1 1 1 0 TspO/MBR family HlyIII PF03006.20 RJW71872.1 - 0.057 13.1 7.7 0.017 14.8 4.8 1.5 2 0 0 2 2 2 0 Haemolysin-III related DUF4293 PF14126.6 RJW71872.1 - 0.066 13.5 10.3 0.094 13.0 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) ABC2_membrane_5 PF13346.6 RJW71872.1 - 0.13 11.8 14.6 0.18 11.3 14.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Virul_fac_BrkB PF03631.15 RJW71872.1 - 0.2 11.3 10.7 0.28 10.8 10.7 1.1 1 0 0 1 1 1 0 Virulence factor BrkB Bax1-I PF01027.20 RJW71872.1 - 0.38 10.6 15.5 1.2 8.9 15.5 1.8 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF1345 PF07077.11 RJW71872.1 - 0.59 9.8 7.2 0.13 12.0 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF4173 PF13777.6 RJW71872.1 - 0.72 9.3 12.6 0.02 14.3 5.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DUF202 PF02656.15 RJW71872.1 - 1.5 9.3 7.7 0.74 10.3 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF4064 PF13273.6 RJW71872.1 - 1.5 9.1 12.5 0.081 13.2 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Pox_P35 PF03213.14 RJW71872.1 - 1.6 7.9 5.4 2.6 7.2 5.4 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein GWT1 PF06423.12 RJW71872.1 - 2.1 8.4 8.9 10 6.2 8.9 2.0 1 1 0 1 1 1 0 GWT1 DHHC PF01529.20 RJW71872.1 - 3.4 7.8 13.3 2.2 8.4 2.0 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF4149 PF13664.6 RJW71872.1 - 3.5 8.0 10.0 4 7.8 3.6 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) DUF2070 PF09843.9 RJW71872.1 - 4 5.6 13.5 4.8 5.4 13.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4131 PF13567.6 RJW71872.1 - 6.5 6.4 9.3 0.7 9.5 2.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Ost5 PF05251.12 RJW71872.1 - 7.6 6.9 17.0 0.94 9.8 6.3 3.1 1 1 2 3 3 3 0 Oligosaccharyltransferase subunit 5 tRNA-synt_1c PF00749.21 RJW71873.1 - 2.1e-106 355.4 0.0 2.1e-106 355.4 0.0 2.2 2 0 0 2 2 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 RJW71873.1 - 1.4e-31 109.7 0.0 6.4e-31 107.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain ProRS-C_1 PF09180.11 RJW71873.1 - 5.4e-17 61.8 0.1 1.4e-16 60.4 0.1 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 RJW71873.1 - 2e-16 60.5 0.0 5.4e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RJW71873.1 - 5.7e-12 45.6 0.0 1.6e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain GST_C_2 PF13410.6 RJW71873.1 - 0.0036 17.3 0.2 0.013 15.5 0.1 2.0 2 0 0 2 2 1 1 Glutathione S-transferase, C-terminal domain Med3 PF11593.8 RJW71873.1 - 0.02 14.1 18.2 0.03 13.5 18.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GST_C_3 PF14497.6 RJW71873.1 - 0.02 15.1 0.0 0.082 13.1 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 RJW71873.1 - 0.094 12.1 0.0 0.094 12.1 0.0 1.8 2 0 0 2 2 1 0 tRNA synthetases class I (C) catalytic domain Presenilin PF01080.17 RJW71873.1 - 0.24 10.1 11.6 0.37 9.5 11.6 1.2 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 RJW71873.1 - 0.3 11.2 3.5 0.72 10.0 3.5 1.6 1 0 0 1 1 1 0 DDHD domain Suf PF05843.14 RJW71873.1 - 3.8 7.4 10.7 6.4 6.7 10.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDC45 PF02724.14 RJW71873.1 - 4.2 5.6 10.7 6.4 4.9 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 RJW71873.1 - 6.4 6.5 18.0 12 5.6 18.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5521 PF17659.1 RJW71873.1 - 8.5 4.1 11.0 12 3.5 11.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) SUIM_assoc PF16619.5 RJW71873.1 - 9 6.4 15.4 30 4.8 15.4 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Arfaptin PF06456.13 RJW71876.1 - 5.9e-68 228.9 3.3 8.7e-68 228.3 3.3 1.2 1 0 0 1 1 1 1 Arfaptin-like domain PDZ_6 PF17820.1 RJW71876.1 - 4.1e-07 29.7 0.0 9.7e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW71876.1 - 2e-06 28.1 0.0 4.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW71876.1 - 3.9e-06 27.1 0.0 1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain BAR PF03114.18 RJW71876.1 - 7.2e-06 25.8 1.2 3.5e-05 23.6 1.2 1.9 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 RJW71876.1 - 4.8e-05 23.2 1.5 0.11 12.2 0.1 2.2 2 0 0 2 2 2 2 BAR domain of APPL family PCI PF01399.27 RJW71877.1 - 0.0034 17.9 0.1 0.013 16.0 0.1 2.0 1 1 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 RJW71877.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain DUF3699 PF12480.8 RJW71877.1 - 0.073 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) RINGv PF12906.7 RJW71878.1 - 2e-14 53.4 9.6 4.2e-14 52.4 9.6 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 RJW71878.1 - 6.1 7.3 12.0 13 6.2 12.0 1.6 1 0 0 1 1 1 0 Ring finger domain Tubulin PF00091.25 RJW71880.1 - 2.9e-70 236.5 0.0 4.6e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW71880.1 - 7.3e-45 152.2 0.2 1.2e-44 151.6 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RJW71880.1 - 3.1e-05 24.3 0.0 8.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RJW71880.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RJW71880.1 - 0.025 13.8 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Cullin PF00888.22 RJW71882.1 - 8.6e-210 698.5 13.3 9.2e-209 695.1 13.3 2.0 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RJW71882.1 - 2e-26 91.8 0.4 7e-26 90.1 0.4 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain HrcA PF01628.21 RJW71882.1 - 0.043 13.7 0.6 0.14 12.1 0.2 2.0 2 0 0 2 2 2 0 HrcA protein C terminal domain DUF4101 PF13355.6 RJW71882.1 - 0.13 12.7 0.4 0.54 10.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) EAP30 PF04157.16 RJW71882.1 - 0.46 9.7 2.3 1 8.6 0.0 2.6 3 0 0 3 3 3 0 EAP30/Vps36 family Glycos_transf_2 PF00535.26 RJW71883.1 - 3.4e-32 111.6 0.0 5.5e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RJW71883.1 - 3.1e-16 59.8 0.2 4.4e-16 59.3 0.2 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 RJW71883.1 - 6.7e-08 32.7 0.0 3.3e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RJW71883.1 - 3.3e-06 26.7 0.4 2.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RJW71883.1 - 0.0059 16.1 0.0 0.03 13.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Zn_Tnp_IS91 PF14319.6 RJW71885.1 - 0.016 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain YAF2_RYBP PF17219.3 RJW71886.1 - 2.4e-08 33.4 0.0 4.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.18 RJW71886.1 - 6.2e-07 28.6 2.5 6.2e-07 28.6 2.5 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others C1_2 PF03107.16 RJW71886.1 - 1.7 9.0 6.5 5.1 7.5 6.5 1.8 1 0 0 1 1 1 0 C1 domain Malic_M PF03949.15 RJW71888.1 - 0.088 12.1 0.9 0.17 11.2 0.9 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain HMG_box PF00505.19 RJW71890.1 - 2.4e-19 69.5 3.4 4.7e-19 68.6 3.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW71890.1 - 4.3e-09 36.8 2.3 8.8e-09 35.8 2.3 1.5 1 0 0 1 1 1 1 HMG-box domain Maf1 PF09174.10 RJW71890.1 - 8.3e-09 35.8 0.0 3.7e-08 33.7 0.0 2.1 1 0 0 1 1 1 1 Maf1 regulator IGFBP PF00219.18 RJW71891.1 - 2.5e-08 34.4 19.1 2.5e-08 34.4 19.1 4.9 5 2 1 6 6 6 1 Insulin-like growth factor binding protein Nuc_deoxyri_tr3 PF11071.8 RJW71893.1 - 0.077 13.1 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ Wtap PF17098.5 RJW71894.1 - 1e-30 106.8 0.6 1e-30 106.8 0.6 2.1 1 1 1 2 2 2 1 WTAP/Mum2p family T3SSipB PF16535.5 RJW71894.1 - 0.0011 19.4 3.3 0.0021 18.6 2.3 1.7 1 1 1 2 2 2 1 Type III cell invasion protein SipB INTS2 PF14750.6 RJW71894.1 - 0.0012 16.5 0.9 0.0017 16.1 0.9 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 OEP PF02321.18 RJW71894.1 - 0.025 14.4 3.3 0.03 14.1 2.6 1.5 1 1 0 1 1 1 0 Outer membrane efflux protein AATF-Che1 PF13339.6 RJW71894.1 - 0.038 14.7 2.4 0.061 14.0 2.4 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor FliD_C PF07195.12 RJW71894.1 - 0.051 13.0 0.2 0.099 12.0 0.1 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Phage_GPO PF05929.11 RJW71894.1 - 0.053 13.1 1.7 0.07 12.7 1.2 1.3 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CHASE3 PF05227.13 RJW71894.1 - 0.06 13.3 3.5 0.091 12.7 0.1 2.2 1 1 0 2 2 2 0 CHASE3 domain Mod_r PF07200.13 RJW71894.1 - 0.087 12.9 5.7 0.089 12.9 4.9 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.12 RJW71894.1 - 0.13 12.7 1.8 16 6.1 0.0 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 RJW71894.1 - 0.18 11.2 2.7 0.21 10.9 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 RJW71894.1 - 0.22 10.3 8.1 0.095 11.6 5.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.16 RJW71894.1 - 1.2 9.7 5.4 4.6 7.8 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 RJW71894.1 - 3.5 5.4 4.9 4.1 5.2 4.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HIP1_clath_bdg PF16515.5 RJW71894.1 - 5.1 7.8 10.8 3.1 8.4 6.9 2.5 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cep57_CLD_2 PF14197.6 RJW71894.1 - 8.4 6.6 10.9 17 5.5 6.5 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 MULE PF10551.9 RJW71895.1 - 5.1e-09 36.4 0.0 7.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain DUF1977 PF09320.11 RJW71896.1 - 2.1e-25 89.0 0.5 4.6e-25 87.9 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 RJW71896.1 - 1.5e-23 82.7 0.1 4.7e-23 81.1 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain HEAT_EZ PF13513.6 RJW71897.1 - 8.1e-30 102.9 1.4 8.3e-10 39.0 0.0 10.7 7 2 6 13 13 12 5 HEAT-like repeat HEAT PF02985.22 RJW71897.1 - 1.3e-25 87.2 14.7 0.015 15.5 0.0 11.4 11 0 0 11 11 10 6 HEAT repeat HEAT_2 PF13646.6 RJW71897.1 - 2.6e-15 56.6 0.0 0.0059 17.0 0.0 6.7 5 3 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 RJW71897.1 - 1.1e-14 54.7 0.0 0.014 15.4 0.0 4.4 3 1 1 4 4 4 4 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 RJW71897.1 - 6.9e-13 48.1 5.4 0.032 14.3 0.0 8.2 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 RJW71897.1 - 1.3e-10 41.8 0.0 0.0025 18.4 0.1 5.7 5 3 4 9 9 7 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 RJW71897.1 - 2.5e-10 40.1 0.0 1.9e-09 37.3 0.0 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 RJW71897.1 - 3.3e-10 39.2 0.6 0.0089 14.6 0.0 4.5 3 2 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.8 RJW71897.1 - 5.6e-07 29.3 0.8 3.1 7.3 0.0 5.3 3 3 2 5 5 5 4 CLASP N terminal MMS19_C PF12460.8 RJW71897.1 - 4e-06 26.2 0.1 0.087 11.9 0.0 4.8 4 1 0 5 5 5 1 RNAPII transcription regulator C-terminal IFRD PF05004.13 RJW71897.1 - 0.021 13.9 0.0 1.1 8.3 0.0 3.2 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 RJW71897.1 - 0.025 14.6 1.3 0.63 10.0 0.1 3.3 5 0 0 5 5 5 0 Myosin-binding striated muscle assembly central Proteasom_PSMB PF10508.9 RJW71897.1 - 0.039 12.5 0.0 0.11 10.9 0.0 1.8 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 RJW71897.1 - 0.04 14.1 0.3 31 4.8 0.0 3.6 5 0 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 RJW71897.1 - 0.085 12.8 0.4 40 4.2 0.0 4.4 5 0 0 5 5 5 0 UME (NUC010) domain MOFRL PF05161.13 RJW71898.1 - 2.8 8.2 5.3 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 MOFRL family Wtap PF17098.5 RJW71899.1 - 1.8e-11 44.2 0.0 6e-11 42.5 0.0 1.8 1 1 1 2 2 2 1 WTAP/Mum2p family Rab5-bind PF09311.11 RJW71899.1 - 0.014 14.8 0.7 0.021 14.2 0.7 1.1 1 0 0 1 1 1 0 Rabaptin-like protein CENP-F_leu_zip PF10473.9 RJW71899.1 - 0.015 15.4 2.1 0.023 14.7 2.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ornatin PF02088.15 RJW71899.1 - 0.13 12.0 0.6 0.55 10.1 0.1 2.2 3 0 0 3 3 3 0 Ornatin DUF4283 PF14111.6 RJW71900.1 - 0.037 13.5 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) zf-C2H2 PF00096.26 RJW71901.1 - 0.001 19.4 1.2 0.004 17.5 1.2 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW71901.1 - 0.0073 17.1 1.7 0.025 15.4 1.7 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW71901.1 - 0.025 14.3 0.3 0.057 13.2 0.3 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 RJW71901.1 - 0.034 14.6 2.9 2.3 8.8 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Asp PF00026.23 RJW71902.1 - 2.3e-31 109.4 0.0 2.9e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW71902.1 - 1.1e-06 28.6 0.1 3.8e-06 26.8 0.2 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 RJW71902.1 - 0.009 16.3 0.1 0.026 14.7 0.0 1.7 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Telomere_Sde2_2 PF13297.6 RJW71902.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal COesterase PF00135.28 RJW71903.1 - 3.4e-21 75.7 0.0 4e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Ras PF00071.22 RJW71905.1 - 8.1e-23 80.8 0.0 1.2e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 RJW71905.1 - 0.026 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B RUN PF02759.19 RJW71906.1 - 1.7e-10 41.0 0.1 2.6e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 RUN domain PID PF00640.23 RJW71906.1 - 2.4e-06 27.6 0.0 9.9e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PDZ_2 PF13180.6 RJW71906.1 - 0.00034 20.9 0.3 0.00066 19.9 0.3 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW71906.1 - 0.00068 19.9 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain AA_permease_2 PF13520.6 RJW71907.1 - 2.4e-31 109.0 30.0 2.9e-31 108.7 30.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RJW71907.1 - 1.4e-15 56.9 26.5 1.7e-15 56.6 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease Oxidored_q2 PF00420.24 RJW71907.1 - 0.057 13.1 0.4 0.057 13.1 0.4 2.9 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L RNA_pol_I_A49 PF06870.12 RJW71908.1 - 3.2e-49 167.8 0.1 4.9e-49 167.2 0.1 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor FRQ PF09421.10 RJW71908.1 - 0.1 10.6 0.0 0.18 9.8 0.0 1.3 1 0 0 1 1 1 0 Frequency clock protein SHQ1 PF04925.15 RJW71909.1 - 6.7e-49 165.8 0.3 1e-48 165.2 0.3 1.2 1 0 0 1 1 1 1 SHQ1 protein Rep_fac-A_C PF08646.10 RJW71910.1 - 1.2e-53 180.8 3.9 1.8e-51 173.7 0.3 2.2 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 RJW71910.1 - 3.9e-34 116.5 0.5 3.4e-32 110.2 0.1 2.4 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 RJW71910.1 - 1e-11 44.6 1.4 1.4e-09 37.8 0.1 3.6 3 1 1 4 4 4 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 RJW71910.1 - 0.00027 20.9 0.3 0.00071 19.6 0.3 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 RJW71910.1 - 0.015 15.0 1.6 0.042 13.5 0.4 2.0 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 POT1 PF02765.17 RJW71910.1 - 0.045 13.6 1.8 8.2 6.3 0.1 3.1 1 1 1 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 IBR PF01485.21 RJW71910.1 - 0.3 11.3 5.0 0.64 10.3 5.0 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 RJW71910.1 - 0.48 10.0 2.4 1.1 8.8 2.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding RVT_1 PF00078.27 RJW71911.1 - 1.2e-07 31.5 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 RJW71912.1 - 1.1e-59 198.9 5.2 2.3e-15 56.8 0.0 8.5 6 3 1 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 RJW71912.1 - 4.2e-05 23.3 2.5 0.41 10.5 0.1 5.1 5 0 0 5 5 5 2 Cadherin-like RET_CLD1 PF17756.1 RJW71912.1 - 0.11 12.7 0.1 9.1 6.6 0.0 3.1 3 0 0 3 3 3 0 RET Cadherin like domain 1 BPS PF08947.10 RJW71912.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 BPS (Between PH and SH2) Syndecan PF01034.20 RJW71912.1 - 5.4 7.0 5.9 0.52 10.3 1.0 1.8 2 0 0 2 2 2 0 Syndecan domain Y_phosphatase PF00102.27 RJW71914.1 - 1.7e-70 237.3 0.0 3.4e-70 236.3 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.10 RJW71914.1 - 1.6e-14 54.0 0.1 6.1e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 FERM C-terminal PH-like domain PDZ PF00595.24 RJW71914.1 - 9.1e-14 51.6 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Y_phosphatase3 PF13350.6 RJW71914.1 - 0.00012 22.2 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PDZ_6 PF17820.1 RJW71914.1 - 0.00012 21.8 0.0 0.00034 20.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain DSPc PF00782.20 RJW71914.1 - 0.0016 18.2 0.0 0.0047 16.7 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RJW71914.1 - 0.0085 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Zip PF02535.22 RJW71915.1 - 6.5e-54 183.4 2.7 1.1e-53 182.6 2.7 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1129 PF06570.11 RJW71915.1 - 1.3 8.5 4.8 11 5.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) zf-RING_2 PF13639.6 RJW71917.1 - 6.8e-06 26.3 6.5 1.5e-05 25.2 6.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RJW71917.1 - 3.7e-05 23.5 6.3 7.3e-05 22.5 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW71917.1 - 0.00043 20.1 6.7 0.00091 19.1 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RJW71917.1 - 0.001 18.9 7.6 0.002 17.9 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RJW71917.1 - 0.001 19.2 8.7 0.0019 18.3 8.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RJW71917.1 - 0.019 15.0 7.0 0.031 14.3 5.6 2.1 1 1 0 1 1 1 0 RING-type zinc-finger DUF1644 PF07800.12 RJW71917.1 - 0.036 14.1 6.3 0.056 13.5 3.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_6 PF14835.6 RJW71917.1 - 0.06 13.2 4.3 0.15 12.0 4.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1929 PF09118.11 RJW71917.1 - 0.33 11.3 2.4 0.54 10.6 1.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1929) zf-rbx1 PF12678.7 RJW71917.1 - 0.53 10.6 4.0 1.7 9.0 4.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain AA_permease_2 PF13520.6 RJW71918.1 - 5.7e-34 117.7 45.6 2.3e-20 72.8 17.8 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 RJW71918.1 - 2.6e-14 52.7 41.0 7.5e-10 38.0 16.1 2.1 2 0 0 2 2 2 2 Amino acid permease Toxin_32 PF08120.11 RJW71918.1 - 3.2 7.6 4.2 12 5.9 0.6 3.0 3 0 0 3 3 3 0 Tamulustoxin family HEAT PF02985.22 RJW71919.1 - 0.0063 16.7 3.8 3 8.4 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 RJW71919.1 - 0.67 10.1 8.2 20 5.4 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat AA_permease_2 PF13520.6 RJW71920.1 - 5e-52 177.2 54.7 6.2e-52 176.8 54.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RJW71920.1 - 3.4e-22 78.7 50.3 4.4e-22 78.3 50.3 1.1 1 0 0 1 1 1 1 Amino acid permease VHL PF01847.16 RJW71921.1 - 0.00026 20.9 0.0 0.83 9.6 0.0 2.4 2 0 0 2 2 2 2 VHL beta domain Phage_holin_3_6 PF07332.11 RJW71922.1 - 0.0027 17.8 0.9 0.0044 17.1 0.9 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4064 PF13273.6 RJW71922.1 - 0.035 14.4 3.3 0.061 13.6 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF202 PF02656.15 RJW71922.1 - 5.6 7.5 8.8 4.3 7.9 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Homeodomain PF00046.29 RJW71923.1 - 4.6e-19 68.0 4.2 9.5e-19 67.0 4.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW71923.1 - 0.016 15.1 0.7 0.049 13.6 0.2 2.0 2 0 0 2 2 2 0 Homeobox KN domain Homez PF11569.8 RJW71923.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Tti2 PF10521.9 RJW71925.1 - 0.0024 17.5 0.2 0.0083 15.7 0.1 2.0 2 1 0 2 2 2 1 Tti2 family NDUFA12 PF05071.16 RJW71926.1 - 7.5e-30 103.6 7.5 8.9e-30 103.4 7.5 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Antimicrobial21 PF14861.6 RJW71929.1 - 3.9 7.3 12.5 4.4 7.1 0.8 3.5 3 1 0 3 3 3 0 Plant antimicrobial peptide Mito_carr PF00153.27 RJW71930.1 - 3.7e-70 231.9 1.7 1.6e-23 82.4 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 RJW71930.1 - 6.5e-14 52.1 5.5 5.6e-05 23.5 1.9 4.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RJW71930.1 - 1.4e-13 49.3 1.9 0.011 15.3 0.2 5.7 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 RJW71930.1 - 1.8e-10 39.9 2.3 0.042 13.8 0.0 5.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 RJW71930.1 - 2.5e-09 36.8 1.8 0.0027 17.5 0.0 4.6 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW71930.1 - 1.2e-06 27.7 1.9 0.064 12.8 0.0 4.6 4 0 0 4 4 4 1 EF hand Clr2_transil PF16761.5 RJW71930.1 - 0.08 13.8 0.0 2.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Transcription-silencing protein, cryptic loci regulator Clr2 Homeodomain PF00046.29 RJW71931.1 - 4.3e-21 74.5 7.1 8.3e-21 73.6 5.5 2.2 2 0 0 2 2 2 1 Homeodomain Ig_3 PF13927.6 RJW71932.1 - 7.7e-58 193.0 2.1 3.5e-12 46.7 0.0 6.9 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 RJW71932.1 - 4.6e-50 167.6 0.0 1.5e-15 57.0 0.0 6.1 5 1 1 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW71932.1 - 1.3e-28 99.1 1.3 5.9e-05 23.3 0.0 5.9 4 1 1 5 5 5 5 Immunoglobulin domain ig PF00047.25 RJW71932.1 - 9.4e-27 93.0 0.5 2.1e-07 31.0 0.0 5.8 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 RJW71932.1 - 6.4e-26 90.7 1.1 8.3e-06 25.9 0.1 7.1 6 2 1 7 7 7 4 Immunoglobulin V-set domain fn3 PF00041.21 RJW71932.1 - 4.7e-13 49.3 1.9 0.022 15.1 0.0 7.0 7 0 0 7 7 7 3 Fibronectin type III domain Ig_6 PF18452.1 RJW71932.1 - 3.3e-11 42.6 0.0 0.17 11.5 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain C2-set_2 PF08205.12 RJW71932.1 - 3.6e-07 30.2 0.0 0.84 9.7 0.0 4.4 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RJW71932.1 - 6.6e-06 26.1 0.0 4.7 7.3 0.0 5.0 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 RJW71932.1 - 0.00059 20.2 0.0 4.7 7.7 0.0 4.7 5 0 0 5 5 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 RJW71932.1 - 0.0016 18.4 0.1 3.4 7.8 0.0 3.8 4 0 0 4 4 4 1 C17orf99 Ig domain Epiglycanin_C PF14654.6 RJW71932.1 - 0.03 14.4 0.0 0.086 12.9 0.0 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region fn3_2 PF16893.5 RJW71932.1 - 0.034 14.3 0.1 16 5.7 0.2 3.1 3 0 0 3 3 2 0 Fibronectin type III domain PRIMA1 PF16101.5 RJW71932.1 - 2.2 8.3 8.1 5.6 7.0 0.1 2.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF2325 PF10087.9 RJW71933.1 - 0.06 13.5 0.1 0.088 12.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) TIL PF01826.17 RJW71933.1 - 0.69 10.2 12.5 6.9 7.0 12.5 2.1 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Dynein_light PF01221.18 RJW71936.1 - 3e-34 117.2 0.1 3.3e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 wnt PF00110.19 RJW71937.1 - 8.7e-100 334.3 14.1 5.5e-59 200.3 9.2 2.1 2 0 0 2 2 2 2 wnt family GatB_N PF02934.15 RJW71938.1 - 0.046 13.1 0.1 0.048 13.0 0.1 1.2 1 0 0 1 1 1 0 GatB/GatE catalytic domain SCVP PF17619.2 RJW71938.1 - 0.091 13.6 0.0 0.12 13.2 0.0 1.2 1 0 0 1 1 1 0 Secreted clade V proteins FAM76 PF16046.5 RJW71938.1 - 0.12 11.7 1.5 0.16 11.3 1.5 1.1 1 0 0 1 1 1 0 FAM76 protein DUF3509 PF12021.8 RJW71940.1 - 0.021 14.5 0.2 0.084 12.6 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3509) SBDS PF01172.18 RJW71941.1 - 1.9e-29 101.6 0.3 4.9e-29 100.2 0.3 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 RJW71941.1 - 3.9e-29 101.0 0.5 6.5e-29 100.3 0.5 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain MRP-S28 PF10213.9 RJW71941.1 - 0.028 14.9 0.1 0.12 12.8 0.0 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit protein Calreticulin PF00262.18 RJW71942.1 - 1.6e-149 497.8 13.5 2e-149 497.5 13.5 1.0 1 0 0 1 1 1 1 Calreticulin family NT5C PF06941.12 RJW71942.1 - 0.031 14.2 0.0 0.088 12.7 0.0 1.7 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Ig_mannosidase PF17753.1 RJW71944.1 - 1.8e-06 27.6 0.2 4.4e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 RJW71944.1 - 0.0017 17.6 0.1 0.0033 16.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Sarcoglycan_1 PF04790.13 RJW71945.1 - 0.035 13.4 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Ribosomal_L28e PF01778.17 RJW71946.1 - 0.47 11.2 3.8 0.43 11.3 0.4 2.7 2 0 0 2 2 2 0 Ribosomal L28e protein family ABC_membrane PF00664.23 RJW71947.1 - 1.2e-110 369.5 28.6 5e-60 203.5 6.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RJW71947.1 - 1.8e-67 226.1 0.1 6.5e-36 123.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RJW71947.1 - 7.2e-15 55.0 1.7 0.0004 19.9 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RJW71947.1 - 1e-10 42.0 0.4 0.0007 19.9 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RJW71947.1 - 1.2e-10 42.0 1.8 0.00022 21.7 0.3 3.1 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 RJW71947.1 - 3.9e-09 35.8 0.4 0.001 17.9 0.0 2.6 3 0 0 3 3 2 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 RJW71947.1 - 5.7e-09 36.2 1.6 0.00063 19.6 0.0 2.5 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 RJW71947.1 - 1.3e-08 35.1 0.3 0.033 14.0 0.1 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RJW71947.1 - 4.3e-08 33.2 0.0 0.008 16.1 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 RJW71947.1 - 9.9e-08 31.6 0.0 0.0039 16.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RJW71947.1 - 1.5e-07 30.9 0.0 0.0072 15.6 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_7 PF12775.7 RJW71947.1 - 6.2e-07 29.1 0.0 0.012 15.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 RJW71947.1 - 1.2e-06 28.4 0.2 0.11 12.2 0.6 3.4 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.20 RJW71947.1 - 1.5e-06 27.6 0.0 0.016 14.4 0.0 2.5 2 0 0 2 2 2 2 G-protein alpha subunit AAA_23 PF13476.6 RJW71947.1 - 2.7e-06 28.0 1.8 0.016 15.7 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 RJW71947.1 - 5.4e-06 26.9 0.2 0.32 11.4 0.1 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RJW71947.1 - 9.8e-06 25.6 0.0 0.14 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 RJW71947.1 - 5.7e-05 23.3 7.6 0.06 13.6 0.3 4.3 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 RJW71947.1 - 0.00012 22.6 0.0 0.47 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 RJW71947.1 - 0.00019 21.4 0.0 0.98 9.3 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain MMR_HSR1 PF01926.23 RJW71947.1 - 0.0003 20.8 0.0 0.56 10.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.6 RJW71947.1 - 0.0011 19.0 0.0 2.2 8.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain NB-ARC PF00931.22 RJW71947.1 - 0.0011 18.2 0.0 2.1 7.4 0.0 2.8 3 0 0 3 3 2 2 NB-ARC domain DUF815 PF05673.13 RJW71947.1 - 0.0012 18.1 0.0 0.51 9.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 RJW71947.1 - 0.0024 17.8 0.1 1.9 8.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 RJW71947.1 - 0.0026 17.9 0.1 0.73 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 RJW71947.1 - 0.003 17.2 0.2 2.4 7.7 0.2 3.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RJW71947.1 - 0.0038 17.0 0.4 9.6 5.9 0.0 4.2 5 0 0 5 5 4 0 IstB-like ATP binding protein RNA_helicase PF00910.22 RJW71947.1 - 0.0058 17.0 0.1 5.8 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RJW71947.1 - 0.0077 16.0 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RJW71947.1 - 0.0089 16.3 0.0 7.1 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RJW71947.1 - 0.01 16.1 0.0 5 7.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RJW71947.1 - 0.014 14.8 0.1 10 5.5 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein Guanylate_kin PF00625.21 RJW71947.1 - 0.017 14.8 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase PRK PF00485.18 RJW71947.1 - 0.019 14.7 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 RJW71947.1 - 0.032 13.8 0.1 9.6 5.8 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 RJW71947.1 - 0.045 13.8 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 RJW71947.1 - 0.051 14.0 0.2 29 5.1 0.0 3.3 3 0 0 3 3 2 0 AAA domain SART-1 PF03343.13 RJW71947.1 - 0.052 12.1 3.7 0.83 8.1 3.2 2.0 1 1 1 2 2 2 0 SART-1 family Viral_helicase1 PF01443.18 RJW71947.1 - 0.057 13.1 0.0 15 5.2 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 RJW71947.1 - 0.063 13.4 0.0 6.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain APS_kinase PF01583.20 RJW71947.1 - 0.073 13.0 0.0 3.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Ploopntkinase3 PF18751.1 RJW71947.1 - 0.079 12.9 0.0 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Sigma54_activat PF00158.26 RJW71947.1 - 0.085 12.5 0.0 22 4.7 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP-synt_ab PF00006.25 RJW71947.1 - 0.11 12.1 0.0 9.3 5.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 RJW71947.1 - 0.11 12.3 0.1 8.3 6.3 0.0 2.9 3 0 0 3 3 2 0 NTPase PduV-EutP PF10662.9 RJW71947.1 - 0.15 11.8 0.6 9.7 5.9 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 RJW71947.1 - 0.16 12.0 0.0 19 5.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family adh_short PF00106.25 RJW71948.1 - 2.2e-18 66.4 0.0 2.7e-17 62.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase RVT_1 PF00078.27 RJW71948.1 - 2.3e-15 56.7 0.0 4.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short_C2 PF13561.6 RJW71948.1 - 9.4e-08 31.9 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RJW71948.1 - 0.00016 21.2 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 RJW71948.1 - 0.0013 18.6 0.1 0.0025 17.8 0.1 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RJW71948.1 - 0.15 11.3 0.1 0.41 9.9 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 7tm_1 PF00001.21 RJW71950.1 - 5.6e-22 78.3 22.0 1.7e-20 73.4 22.0 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PMT_2 PF13231.6 RJW71950.1 - 0.0091 16.2 0.0 0.0091 16.2 0.0 3.4 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase UPF0184 PF03670.13 RJW71951.1 - 2.1e-07 31.2 0.1 2.4e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) DUF892 PF05974.12 RJW71951.1 - 0.017 15.2 0.0 0.018 15.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Sec34 PF04136.15 RJW71951.1 - 0.049 13.5 0.1 0.056 13.3 0.1 1.0 1 0 0 1 1 1 0 Sec34-like family SIR2 PF02146.17 RJW71952.1 - 3.1e-51 173.8 0.0 4.7e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family rve PF00665.26 RJW71952.1 - 4.7e-10 39.7 0.0 8.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RJW71952.1 - 0.029 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RhoGAP PF00620.27 RJW71953.1 - 1.3e-20 73.7 0.0 2.8e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Peptidase_M24_C PF16188.5 RJW71954.1 - 0.11 12.5 0.3 0.79 9.8 0.4 2.0 1 1 1 2 2 2 0 C-terminal region of peptidase_M24 Ras PF00071.22 RJW71956.1 - 1.8e-61 206.5 0.3 2.3e-61 206.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW71956.1 - 6.3e-35 120.0 0.2 9.7e-35 119.4 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW71956.1 - 2.2e-15 56.5 0.2 3e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW71956.1 - 9.8e-06 25.1 0.2 1.2e-05 24.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RJW71956.1 - 7.2e-05 22.4 0.2 0.00021 20.9 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RJW71956.1 - 0.0002 21.3 0.1 0.37 10.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 RJW71956.1 - 0.0017 18.2 0.1 0.005 16.7 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 RJW71956.1 - 0.0029 17.7 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RJW71956.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 RJW71956.1 - 0.023 14.3 0.0 0.2 11.2 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 RJW71956.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 RJW71956.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 RJW71956.1 - 0.17 10.7 0.1 2 7.2 0.0 2.0 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) MoaE PF02391.17 RJW71959.1 - 7.3e-26 90.7 0.0 1.5e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 MoaE protein zf-RING_10 PF16685.5 RJW71959.1 - 0.088 13.0 1.0 0.28 11.4 1.0 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 Lectin_C PF00059.21 RJW71960.1 - 5.1e-105 345.7 14.9 4.2e-15 56.4 0.1 11.7 11 1 0 11 11 11 10 Lectin C-type domain UL45 PF05473.12 RJW71960.1 - 1.9e-09 37.5 10.7 0.042 13.5 0.1 6.8 7 0 0 7 7 7 4 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 RJW71960.1 - 0.25 11.8 2.2 9.6 6.7 0.0 4.4 5 0 0 5 5 5 0 Extracellular link domain ubiquitin PF00240.23 RJW71961.1 - 1.6e-17 63.0 0.0 3.3e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 RJW71961.1 - 2.2e-08 34.1 7.3 4.9e-08 33.0 7.3 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 RJW71961.1 - 3.5e-06 26.8 0.3 7.1e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RJW71961.1 - 0.0075 16.7 0.2 0.036 14.5 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain MRPL52 PF18699.1 RJW71961.1 - 0.069 13.3 0.8 0.15 12.3 0.8 1.5 1 0 0 1 1 1 0 Mitoribosomal protein mL52 SKA1 PF07160.12 RJW71961.1 - 0.08 12.8 3.9 0.15 11.9 3.9 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Aldolase_II PF00596.21 RJW71962.1 - 2.5e-38 131.9 0.5 4.2e-38 131.2 0.5 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Mso1_Sec1_bdg PF14475.6 RJW71963.1 - 0.034 13.7 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Enkurin PF13864.6 RJW71965.1 - 0.24 11.9 2.0 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 Calmodulin-binding mit_SMPDase PF14724.6 RJW71966.1 - 1.1e-34 119.6 3.1 1e-22 80.0 3.8 3.5 2 1 0 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase HTH_9 PF08221.11 RJW71966.1 - 0.14 12.3 0.1 23 5.2 0.0 2.5 1 1 1 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF1599 PF07659.11 RJW71967.1 - 0.2 12.1 0.4 17 5.9 0.0 2.5 2 0 0 2 2 2 0 Nucleotide modification associated domain 1 Peptidase_C1 PF00112.23 RJW71970.1 - 3.1e-66 223.6 0.0 4.4e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW71970.1 - 5.1e-12 46.0 3.3 7.9e-12 45.4 3.3 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW71970.1 - 0.00042 19.2 0.2 0.074 11.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family RRM_1 PF00076.22 RJW71971.1 - 6.3e-43 144.4 0.0 1.4e-24 85.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 RJW71971.1 - 1.7e-21 77.1 0.8 6.3e-21 75.3 0.0 2.2 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.6 RJW71971.1 - 0.00014 21.8 0.0 0.091 12.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 RJW71971.1 - 0.00028 20.7 0.0 0.62 10.0 0.0 2.8 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 RJW71971.1 - 0.0077 15.8 0.0 1.1 8.9 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 RJW71971.1 - 0.08 12.8 0.0 5.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) RRM_7 PF16367.5 RJW71971.1 - 0.19 11.9 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Presenilin PF01080.17 RJW71971.1 - 1.1 7.9 5.2 1.5 7.5 5.2 1.1 1 0 0 1 1 1 0 Presenilin Myosin_head PF00063.21 RJW71972.1 - 9.6e-294 975.9 0.0 1.3e-293 975.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 RJW71972.1 - 8.8e-08 31.9 0.1 1.8e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 RJW71972.1 - 3.4e-07 28.5 28.4 4.4e-07 28.2 28.4 1.1 1 0 0 1 1 1 1 Myosin tail DUF812 PF05667.11 RJW71972.1 - 0.00025 20.1 8.4 0.00054 19.0 8.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) APG6_N PF17675.1 RJW71972.1 - 0.0023 18.5 13.9 0.0023 18.5 13.9 1.8 2 0 0 2 2 1 1 Apg6 coiled-coil region AAA_22 PF13401.6 RJW71972.1 - 0.0024 18.2 1.4 0.0095 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RJW71972.1 - 0.0047 17.3 1.3 0.037 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Rootletin PF15035.6 RJW71972.1 - 0.0052 16.8 13.4 0.011 15.8 13.4 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion IQ PF00612.27 RJW71972.1 - 0.0053 16.4 5.9 0.01 15.5 0.9 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif FapA PF03961.13 RJW71972.1 - 0.016 13.8 5.3 0.028 13.0 5.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3450 PF11932.8 RJW71972.1 - 0.041 13.2 12.6 0.086 12.1 12.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 RJW71972.1 - 0.082 11.8 16.4 0.17 10.7 16.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GPO PF05929.11 RJW71972.1 - 1.3 8.5 8.4 0.12 11.9 3.0 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1664 PF07889.12 RJW71972.1 - 2 8.5 8.6 0.1 12.6 2.3 2.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 RJW71972.1 - 2.4 8.9 11.0 9.4 6.9 11.0 2.1 1 0 0 1 1 1 0 Initiation control protein YabA ADIP PF11559.8 RJW71972.1 - 3.7 7.6 18.2 11 6.1 18.2 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding AATF-Che1 PF13339.6 RJW71972.1 - 3.9 8.1 10.4 0.74 10.5 5.4 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF4407 PF14362.6 RJW71972.1 - 4.8 6.4 10.5 0.12 11.6 3.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 RJW71972.1 - 5.5 4.8 9.3 0.59 8.0 4.8 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 RJW71972.1 - 9.5 5.2 17.0 17 4.4 17.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NUC194 PF08163.12 RJW71973.1 - 2e-34 119.2 0.0 1.1e-18 67.4 0.0 2.7 3 0 0 3 3 3 2 NUC194 domain PI3_PI4_kinase PF00454.27 RJW71973.1 - 0.0004 20.3 0.0 0.0013 18.6 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase gag_pre-integrs PF13976.6 RJW71973.1 - 0.076 12.9 0.0 0.84 9.5 0.0 2.7 3 0 0 3 3 3 0 GAG-pre-integrase domain R3H PF01424.22 RJW71974.1 - 0.11 12.5 0.0 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 R3H domain Astacin PF01400.24 RJW71975.1 - 2.6e-70 236.0 0.0 3.5e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 RJW71975.1 - 0.0049 16.7 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 Matrixin DUF3659 PF12396.8 RJW71975.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) DUF4768 PF15989.5 RJW71976.1 - 0.045 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4768) PKD PF00801.20 RJW71977.1 - 1.5e-24 85.6 14.6 3.2e-11 42.9 0.1 7.0 6 0 0 6 6 6 5 PKD domain REJ PF02010.15 RJW71977.1 - 4.3e-16 58.8 3.3 4.8e-16 58.6 1.0 2.2 2 1 1 3 3 3 1 REJ domain WSC PF01822.19 RJW71977.1 - 0.00041 20.5 5.3 0.00041 20.5 5.3 2.4 2 0 0 2 2 2 1 WSC domain PKD_3 PF16820.5 RJW71977.1 - 0.019 14.7 0.8 0.31 10.8 0.1 3.4 3 0 0 3 3 3 0 PKD-like domain YlqD PF11068.8 RJW71977.1 - 0.2 12.0 0.3 0.43 11.0 0.3 1.6 1 0 0 1 1 1 0 YlqD protein EIF_2_alpha PF07541.12 RJW71977.1 - 0.22 11.6 0.2 0.74 9.9 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit DUF5578 PF17741.1 RJW71978.1 - 4e-123 410.1 1.6 5.7e-123 409.6 1.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5578) CAP PF00188.26 RJW71980.1 - 1.5e-14 54.9 0.1 4.6e-14 53.3 0.1 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family WD40 PF00400.32 RJW71982.1 - 4.3e-08 33.7 0.8 0.014 16.2 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW71982.1 - 4.3e-05 23.7 0.0 0.003 17.8 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 RJW71982.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 CPSF A subunit region Topoisom_I_N PF02919.15 RJW71984.1 - 2.6e-99 331.0 1.7 2.6e-99 331.0 1.7 2.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 RJW71984.1 - 9.4e-98 326.1 4.5 9.4e-98 326.1 4.5 2.1 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 RJW71984.1 - 1.2e-33 114.8 1.3 5.3e-33 112.8 1.3 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain Syntaxin_2 PF14523.6 RJW71984.1 - 0.0029 17.9 7.4 0.0029 17.9 7.4 2.8 2 0 0 2 2 2 1 Syntaxin-like protein DUF3437 PF11919.8 RJW71984.1 - 0.35 10.8 1.7 0.61 10.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) HTH_Tnp_Mu_2 PF09039.11 RJW71984.1 - 0.46 10.6 4.3 0.21 11.7 0.7 2.4 3 0 0 3 3 3 0 Mu DNA binding, I gamma subdomain Exonuc_VII_L PF02601.15 RJW71984.1 - 5.7 6.4 12.2 2.6 7.5 8.3 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4407 PF14362.6 RJW71984.1 - 6 6.1 9.5 12 5.1 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1993 PF09351.10 RJW71984.1 - 8 6.6 8.4 23 5.1 2.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) SGT1 PF07093.11 RJW71985.1 - 2.8e-75 253.9 1.6 2.9e-44 151.5 0.1 2.7 3 0 0 3 3 3 2 SGT1 protein Metallophos PF00149.28 RJW71987.1 - 1.1e-37 130.5 0.0 1.7e-37 129.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 RJW71987.1 - 0.024 14.0 0.1 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) CTU2 PF10288.9 RJW71988.1 - 9.5e-11 41.9 0.4 9.5e-11 41.9 0.4 1.9 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 RJW71988.1 - 1.9e-09 37.5 0.0 4.4e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 PP-loop family zf-C2H2_3 PF13878.6 RJW71988.1 - 0.51 10.2 0.1 0.51 10.2 0.1 3.2 3 1 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO SOCS_box PF07525.16 RJW71989.1 - 9.6e-08 32.3 2.3 1.9e-07 31.3 2.3 1.6 1 0 0 1 1 1 1 SOCS box Ank_4 PF13637.6 RJW71989.1 - 0.0043 17.6 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RT_RNaseH PF17917.1 RJW71991.1 - 0.074 13.3 0.0 3.9 7.8 0.0 2.4 1 1 1 2 2 2 0 RNase H-like domain found in reverse transcriptase Arf PF00025.21 RJW71992.1 - 9.7e-52 174.9 0.0 1.2e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RJW71992.1 - 3.3e-12 46.7 0.0 4.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RJW71992.1 - 4.8e-12 45.7 0.0 6.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 RJW71992.1 - 1.8e-10 40.6 0.0 2.1e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 RJW71992.1 - 2.5e-08 33.5 0.1 2.4e-05 23.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 RJW71992.1 - 2.9e-07 30.6 0.0 1.5e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RJW71992.1 - 0.00023 20.8 0.1 0.0085 15.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RJW71992.1 - 0.00067 19.1 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MeaB PF03308.16 RJW71992.1 - 0.0014 17.7 0.1 0.0028 16.7 0.1 1.6 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 RJW71992.1 - 0.014 14.9 0.2 0.12 12.0 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF4537 PF15057.6 RJW71994.1 - 2.8e-06 27.4 0.0 5.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) VWA_CoxE PF05762.14 RJW71994.1 - 0.025 13.9 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein VWA PF00092.28 RJW71994.1 - 0.031 14.5 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 RJW71994.1 - 0.031 14.9 0.0 0.061 14.0 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain RabGAP-TBC PF00566.18 RJW71996.1 - 9.7e-21 74.4 0.1 1.4e-20 73.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain VCBS PF13517.6 RJW71996.1 - 4.2e-14 52.9 10.4 0.00042 20.9 0.7 5.3 2 1 4 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 RJW71996.1 - 8.3e-07 29.0 18.6 0.51 10.5 0.0 6.0 6 0 0 6 6 6 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 RJW71996.1 - 0.039 13.3 1.0 3.2 7.1 0.1 3.4 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region Med18 PF09637.10 RJW72000.1 - 5e-07 29.8 0.0 2.7e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Med18 protein BHD_3 PF10405.9 RJW72001.1 - 1.2e-23 83.3 0.0 2.5e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 RJW72001.1 - 2e-19 69.1 0.4 6.8e-18 64.2 0.1 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 RJW72001.1 - 1e-11 45.6 0.9 1e-11 45.6 0.9 3.8 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 RJW72001.1 - 0.0064 16.9 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily DnaJ PF00226.31 RJW72002.1 - 1.1e-27 95.9 3.6 1.7e-27 95.3 3.6 1.3 1 0 0 1 1 1 1 DnaJ domain SF1-HH PF16275.5 RJW72004.1 - 4.7e-39 133.2 3.7 4.7e-39 133.2 3.7 2.1 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 RJW72004.1 - 8.9e-08 31.9 0.6 2.5e-07 30.4 0.6 1.8 1 1 0 1 1 1 1 KH domain Coiled PF05710.12 RJW72004.1 - 0.0083 16.9 0.4 0.02 15.7 0.4 1.6 1 0 0 1 1 1 1 Coiled coil zf-CCHC PF00098.23 RJW72004.1 - 0.013 15.5 0.8 0.021 14.9 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle KH_5 PF13184.6 RJW72004.1 - 0.19 11.8 0.4 0.63 10.2 0.0 1.9 2 0 0 2 2 2 0 NusA-like KH domain CCDC-167 PF15188.6 RJW72004.1 - 2.6 8.4 4.8 4.1 7.8 0.2 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 CUB PF00431.20 RJW72005.1 - 4.5e-07 30.2 0.0 0.057 13.8 0.0 3.9 5 0 0 5 5 5 2 CUB domain GATA PF00320.27 RJW72006.1 - 5.5e-14 51.5 5.0 5.5e-14 51.5 5.0 2.6 2 1 0 2 2 2 1 GATA zinc finger Vps36-NZF-N PF16988.5 RJW72006.1 - 0.024 14.0 0.9 0.15 11.5 0.3 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TF_Zn_Ribbon PF08271.12 RJW72006.1 - 0.11 12.0 6.0 0.13 11.8 0.9 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_3 PF13878.6 RJW72006.1 - 0.54 10.1 4.4 6.6 6.6 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO polyprenyl_synt PF00348.17 RJW72008.1 - 2.7e-07 29.9 0.0 5.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase PAM2 PF07145.15 RJW72008.1 - 0.39 10.5 1.9 2.3 8.1 0.3 2.9 3 0 0 3 3 3 0 Ataxin-2 C-terminal region PPI_Ypi1 PF07491.11 RJW72013.1 - 4.9e-07 29.5 0.8 4.9e-07 29.5 0.8 2.6 3 1 0 3 3 3 1 Protein phosphatase inhibitor IMUP PF15761.5 RJW72013.1 - 0.061 14.0 2.6 0.061 14.0 2.6 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein AAA PF00004.29 RJW72014.1 - 4.4e-36 124.2 0.1 1.7e-35 122.4 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RJW72014.1 - 5.2e-08 32.6 0.1 1.4e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 RJW72014.1 - 8.1e-07 29.0 0.0 2.8e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 RJW72014.1 - 2.2e-05 24.6 0.0 0.00044 20.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RJW72014.1 - 0.00021 21.3 0.0 0.00098 19.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FliG_N PF14842.6 RJW72014.1 - 0.006 17.1 0.2 0.042 14.4 0.1 2.3 2 0 0 2 2 2 1 FliG N-terminal domain TniB PF05621.11 RJW72014.1 - 0.01 15.2 0.1 1.4 8.3 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein AAA_16 PF13191.6 RJW72014.1 - 0.016 15.6 3.2 0.047 14.1 0.5 2.8 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 RJW72014.1 - 0.03 14.6 1.1 0.86 9.9 0.1 3.3 2 1 1 3 3 3 0 AAA domain Mg_chelatase PF01078.21 RJW72014.1 - 0.04 13.3 0.0 0.097 12.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 RJW72014.1 - 0.073 12.2 0.0 0.26 10.4 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 RJW72014.1 - 0.091 13.1 0.0 0.3 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Linocin_M18 PF04454.12 RJW72014.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Encapsulating protein for peroxidase NACHT PF05729.12 RJW72014.1 - 0.13 12.1 0.2 1.5 8.7 0.2 2.5 1 1 0 1 1 1 0 NACHT domain PAP2 PF01569.21 RJW72015.1 - 1.5e-25 89.5 2.8 1.5e-25 89.5 2.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 RJW72015.1 - 8.1e-05 22.4 2.3 0.00016 21.4 2.3 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 RJW72015.1 - 0.01 16.3 1.0 0.01 16.3 1.0 2.1 2 1 0 2 2 2 0 PAP2 superfamily C-terminal GTP1_OBG PF01018.22 RJW72017.1 - 1.7e-46 157.7 1.3 2.4e-46 157.2 1.3 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 RJW72017.1 - 4.4e-20 71.9 0.0 7.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RJW72017.1 - 1.5e-08 34.3 0.0 5.2e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RJW72017.1 - 0.0091 16.1 0.0 3.8 7.5 0.0 2.3 2 0 0 2 2 2 2 Dynamin family PI3_PI4_kinase PF00454.27 RJW72018.1 - 8.5e-49 166.6 0.0 2.3e-48 165.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 RJW72018.1 - 1.5e-24 86.9 0.5 2.5e-24 86.1 0.5 1.4 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 RJW72018.1 - 1.2e-16 60.2 0.0 5e-16 58.2 0.0 2.2 1 0 0 1 1 1 1 FATC domain UME PF08064.13 RJW72018.1 - 1.1e-11 44.6 0.1 3.8e-11 42.8 0.1 2.1 1 0 0 1 1 1 1 UME (NUC010) domain DUF4042 PF13251.6 RJW72018.1 - 0.016 14.9 0.2 0.14 11.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) DUF3385 PF11865.8 RJW72018.1 - 0.075 12.9 0.1 0.51 10.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Cpn60_TCP1 PF00118.24 RJW72019.1 - 1.9e-57 195.0 5.4 2.2e-57 194.8 5.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ToxB_N PF18224.1 RJW72020.1 - 0.017 15.0 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 ToxB N-terminal domain 7tm_1 PF00001.21 RJW72022.1 - 1.2e-07 31.4 18.1 1.2e-07 31.4 18.1 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TIR_2 PF13676.6 RJW72023.1 - 2.1e-06 28.3 0.0 7.5e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 TIR domain Flagellin_IN PF07196.13 RJW72023.1 - 0.1 12.8 0.1 0.93 9.7 0.0 2.7 2 0 0 2 2 2 0 Flagellin hook IN motif Integrase_H2C2 PF17921.1 RJW72027.1 - 0.061 13.4 0.0 0.75 9.9 0.0 2.1 2 0 0 2 2 2 0 Integrase zinc binding domain RVT_1 PF00078.27 RJW72028.1 - 2e-18 66.7 0.0 2.8e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TIR_2 PF13676.6 RJW72029.1 - 2.9e-10 40.8 0.0 1.4e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 TIR domain Homeobox_KN PF05920.11 RJW72035.1 - 2.5e-16 59.3 0.5 1.6e-15 56.7 0.2 2.6 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 RJW72035.1 - 6.3e-07 29.1 3.5 8.3e-07 28.8 1.8 2.1 2 0 0 2 2 2 1 Homeodomain MOLO1 PF17175.4 RJW72036.1 - 7.6e-22 77.7 0.0 1.2e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 RJW72036.1 - 0.0049 17.0 0.0 0.59 10.3 0.0 2.4 2 0 0 2 2 2 2 TPM domain Peptidase_C1 PF00112.23 RJW72038.1 - 3e-131 436.1 0.1 2.1e-66 224.1 0.0 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW72038.1 - 8.3e-20 71.0 12.6 1e-10 41.9 0.3 2.9 3 0 0 3 3 3 2 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW72038.1 - 9.7e-10 37.8 4.8 0.021 13.6 0.0 5.2 4 2 1 5 5 5 4 Peptidase C1-like family 7TM_GPCR_Str PF10326.9 RJW72038.1 - 0.015 14.6 0.2 0.03 13.7 0.2 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str DUF3684 PF12449.8 RJW72038.1 - 0.37 8.5 1.9 0.85 7.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3684) TPR_12 PF13424.6 RJW72039.1 - 9.8e-16 57.8 9.9 4.8e-07 30.0 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 RJW72039.1 - 8.6e-11 41.4 2.3 0.0002 21.1 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW72039.1 - 0.00076 19.5 0.4 0.44 10.9 0.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW72039.1 - 0.0076 16.2 6.9 0.4 10.8 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RJW72039.1 - 0.015 15.1 7.4 0.5 10.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RCC1 PF00415.18 RJW72040.1 - 1.4e-31 108.8 7.1 2.9e-10 40.6 0.0 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RJW72040.1 - 1.1e-23 82.4 24.1 3.9e-10 39.3 0.6 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat GCS PF03074.16 RJW72041.1 - 4.6e-155 516.5 0.0 6e-155 516.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase CAP PF00188.26 RJW72043.1 - 4.3e-12 47.0 0.0 3.2e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 Cysteine-rich secretory protein family PI3_PI4_kinase PF00454.27 RJW72044.1 - 5.1e-23 82.2 0.0 7.1e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 RJW72044.1 - 2.9e-05 23.8 0.0 7.3e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 FATC domain HMG_box PF00505.19 RJW72045.1 - 1.1e-21 77.0 1.4 2.2e-21 76.0 1.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW72045.1 - 3.8e-08 33.8 0.8 8.7e-08 32.7 0.8 1.6 1 0 0 1 1 1 1 HMG-box domain RVT_1 PF00078.27 RJW72047.1 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RCS1 PF07326.11 RJW72050.1 - 0.0061 16.5 0.2 0.0071 16.3 0.2 1.3 1 0 0 1 1 1 1 Regulator of chromosome segregation 1 Terminase_4 PF05119.12 RJW72050.1 - 0.073 13.5 0.0 0.13 12.7 0.0 1.4 1 1 0 1 1 1 0 Phage terminase, small subunit Peptidase_C1 PF00112.23 RJW72051.1 - 1.9e-55 188.3 0.0 2.9e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Neur_chan_LBD PF02931.23 RJW72054.1 - 5e-43 147.1 1.7 7e-42 143.3 1.7 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW72054.1 - 0.19 11.8 4.9 0.3 11.1 4.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tubulin PF00091.25 RJW72055.1 - 9.6e-69 231.5 0.0 1.6e-68 230.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW72055.1 - 3.4e-42 143.6 0.1 5.6e-42 142.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RJW72055.1 - 5.6e-05 23.4 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 RJW72055.1 - 0.012 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 RJW72055.1 - 0.043 13.5 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain AMP-binding PF00501.28 RJW72056.1 - 2.5e-92 309.7 0.1 3.1e-92 309.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RJW72056.1 - 0.0085 17.0 0.0 0.02 15.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_transf_25 PF01755.17 RJW72057.1 - 7.7e-26 91.2 0.0 1.7e-24 86.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 RJW72057.1 - 2.7e-06 27.8 0.6 9.3e-06 26.1 0.6 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 RJW72057.1 - 0.00029 20.7 0.0 3.4 7.5 0.0 3.4 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 RJW72057.1 - 0.09 12.2 0.0 5.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 21 Anp1 PF03452.14 RJW72057.1 - 0.11 11.9 0.3 0.62 9.4 0.3 1.9 1 1 0 1 1 1 0 Anp1 IQCJ-SCHIP1 PF15157.6 RJW72060.1 - 0.1 12.4 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif HIT PF01230.23 RJW72061.1 - 5.7e-27 94.3 0.0 1e-26 93.5 0.0 1.4 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 RJW72061.1 - 1.8e-20 73.5 1.2 1.2e-19 70.8 1.2 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Ank_4 PF13637.6 RJW72062.1 - 2.9e-22 78.7 9.9 8.1e-11 42.2 0.7 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW72062.1 - 2.6e-16 60.0 1.0 3.9e-16 59.4 1.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW72062.1 - 5e-15 55.4 6.0 4.2e-09 36.5 0.7 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RJW72062.1 - 4e-13 49.2 0.8 1.8e-05 25.0 0.3 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RJW72062.1 - 2.4e-10 39.7 4.1 3.9e-05 23.7 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Hexapep PF00132.24 RJW72063.1 - 4.7e-05 22.9 9.3 0.12 12.1 0.1 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Gemin6 PF06372.12 RJW72064.1 - 8.7e-19 67.7 0.0 1.4e-18 67.0 0.0 1.3 1 1 0 1 1 1 1 Gemin6 protein AD PF09793.9 RJW72064.1 - 0.024 14.8 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain AcetylCoA_hydro PF02550.15 RJW72064.1 - 0.073 13.1 0.0 0.71 9.8 0.0 1.9 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase N-terminal domain PQQ PF01011.21 RJW72064.1 - 0.21 11.6 0.6 4 7.5 0.0 2.8 3 1 1 4 4 4 0 PQQ enzyme repeat Cadherin PF00028.17 RJW72065.1 - 5.4e-69 228.7 7.2 7.4e-12 45.6 0.0 8.2 7 2 0 7 7 7 7 Cadherin domain Cadherin_3 PF16184.5 RJW72065.1 - 1.4e-09 37.9 5.1 0.032 14.2 0.0 5.7 6 0 0 6 6 6 3 Cadherin-like Cadherin_2 PF08266.12 RJW72065.1 - 0.034 14.0 5.6 80 3.2 3.5 5.6 5 1 0 5 5 5 0 Cadherin-like PQQ PF01011.21 RJW72065.1 - 0.035 14.0 0.0 1.1 9.3 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat Cadherin_4 PF17803.1 RJW72065.1 - 2 9.1 16.6 1.8 9.2 0.2 5.2 5 0 0 5 5 5 0 Bacterial cadherin-like domain Peptidase_C1 PF00112.23 RJW72066.1 - 1.9e-131 436.8 0.1 5.8e-67 226.0 0.1 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW72066.1 - 4.9e-11 42.9 1.0 1.2e-10 41.7 1.0 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW72066.1 - 1.5e-09 37.1 4.9 0.00098 18.0 0.1 4.1 4 0 0 4 4 4 4 Peptidase C1-like family Pro_isomerase PF00160.21 RJW72069.1 - 1e-51 175.3 0.0 1.8e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 RJW72069.1 - 1.2e-09 38.6 1.0 0.031 15.2 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW72069.1 - 0.0069 16.7 0.1 2.3 8.6 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2345 PF10106.9 RJW72069.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Aa_trans PF01490.18 RJW72070.1 - 9.8e-46 156.3 19.5 1.2e-45 156.0 19.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RJW72070.1 - 0.00015 20.9 18.4 0.00015 20.9 18.4 1.6 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family RPN13_C PF16550.5 RJW72071.1 - 3.3e-25 88.4 1.3 4.5e-25 88.0 0.5 1.7 2 0 0 2 2 2 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 RJW72071.1 - 1.2e-21 77.1 0.3 1.9e-21 76.4 0.3 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Peptidase_M13 PF01431.21 RJW72072.1 - 0.11 12.1 0.1 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M13 Peptidase_C1 PF00112.23 RJW72073.1 - 3.2e-73 246.4 2.1 4.2e-73 246.0 2.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW72073.1 - 1.4e-11 44.7 0.0 2.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RJW72073.1 - 4e-06 25.9 0.3 0.00065 18.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Apc13p PF05839.11 RJW72074.1 - 0.21 11.8 0.2 0.41 10.9 0.2 1.5 1 1 0 1 1 1 0 Apc13p protein Vps53_N PF04100.12 RJW72075.1 - 1.2e-86 291.0 7.5 3.7e-50 171.0 0.1 2.3 2 0 0 2 2 2 2 Vps53-like, N-terminal AAA_13 PF13166.6 RJW72075.1 - 0.012 14.3 2.9 0.02 13.6 2.9 1.3 1 0 0 1 1 1 0 AAA domain Tropomyosin PF00261.20 RJW72075.1 - 0.02 14.3 1.8 0.038 13.3 1.8 1.4 1 0 0 1 1 1 0 Tropomyosin Pept_tRNA_hydro PF01195.19 RJW72075.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase Vps54_N PF10475.9 RJW72075.1 - 0.14 11.5 3.9 0.16 11.2 2.0 2.0 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF932 PF06067.11 RJW72075.1 - 0.27 11.0 1.5 0.62 9.8 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF932) COG5 PF10392.9 RJW72075.1 - 1.5 9.0 7.7 0.61 10.3 2.2 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 XhlA PF10779.9 RJW72075.1 - 1.8 8.8 4.2 3.7 7.8 0.8 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Fib_alpha PF08702.10 RJW72075.1 - 5.1 7.3 6.4 6.5 6.9 4.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PLAT PF01477.23 RJW72076.1 - 1.3e-18 67.6 0.1 4.1e-10 40.2 0.0 5.6 6 0 0 6 6 6 2 PLAT/LH2 domain FPL PF09758.9 RJW72077.1 - 2.7e-58 196.2 9.1 5.1e-58 195.3 9.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein Pyr_redox_2 PF07992.14 RJW72078.1 - 1e-29 103.7 0.0 4.6e-29 101.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 RJW72078.1 - 3e-12 47.0 0.1 3.4e-06 27.4 0.1 3.0 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term DAO PF01266.24 RJW72078.1 - 0.014 15.0 4.4 1.6 8.3 1.5 3.8 3 1 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RJW72078.1 - 0.026 14.8 0.5 0.026 14.8 0.5 2.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RJW72078.1 - 0.039 14.5 0.2 4.7 7.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RJW72078.1 - 0.088 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 RJW72078.1 - 0.1 11.9 0.5 1.3 8.2 0.8 2.6 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RJW72078.1 - 0.18 11.8 2.7 19 5.2 0.7 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding Thi4 PF01946.17 RJW72078.1 - 0.18 11.0 0.2 0.33 10.2 0.2 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 RJW72078.1 - 0.24 10.1 2.5 0.39 9.4 1.0 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 RJW72078.1 - 0.94 8.5 6.0 0.1 11.6 1.6 1.6 2 0 0 2 2 2 0 FAD binding domain eIF-6 PF01912.18 RJW72080.1 - 6.4e-80 267.2 3.1 1.2e-79 266.4 1.2 1.8 1 1 1 2 2 2 1 eIF-6 family Invas_SpaK PF03519.14 RJW72081.1 - 0.11 12.6 0.0 0.54 10.4 0.1 2.1 2 1 0 2 2 2 0 Invasion protein B family AA_permease PF00324.21 RJW72082.1 - 2.3e-62 211.2 30.1 1.8e-41 142.3 4.9 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 RJW72082.1 - 1.1e-45 156.5 1.4 8.4e-15 54.7 0.0 3.1 2 1 1 3 3 3 3 Solute carrier family 12 DUF4600 PF15372.6 RJW72083.1 - 1e-37 129.4 8.7 7.7e-37 126.6 2.8 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4600) SEO_N PF14576.6 RJW72083.1 - 0.0077 15.4 3.0 0.9 8.6 0.2 2.7 1 1 2 3 3 3 2 Sieve element occlusion N-terminus Fib_alpha PF08702.10 RJW72083.1 - 0.02 15.1 3.7 0.033 14.4 3.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Helo_like_N PF17111.5 RJW72083.1 - 0.027 13.8 3.0 2 7.8 0.1 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF3781 PF12636.7 RJW72083.1 - 0.032 14.1 0.2 0.084 12.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) ST7 PF04184.12 RJW72083.1 - 0.035 12.6 1.4 0.041 12.3 1.4 1.1 1 0 0 1 1 1 0 ST7 protein TCTP PF00838.17 RJW72083.1 - 0.063 13.6 0.5 0.13 12.6 0.2 1.6 1 1 0 1 1 1 0 Translationally controlled tumour protein CorA PF01544.18 RJW72083.1 - 0.068 12.5 1.4 0.088 12.1 1.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SesA PF17107.5 RJW72083.1 - 0.075 13.2 0.7 0.3 11.3 0.8 1.9 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MIS13 PF08202.11 RJW72083.1 - 0.15 11.4 4.3 0.24 10.7 4.1 1.4 1 1 0 1 1 1 0 Mis12-Mtw1 protein family E2F_CC-MB PF16421.5 RJW72083.1 - 0.23 11.9 2.7 1.1 9.6 0.4 2.2 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF16 PF01519.16 RJW72083.1 - 0.36 11.4 4.3 1.4 9.4 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Csm1_N PF18504.1 RJW72083.1 - 0.64 10.4 5.2 0.71 10.3 1.9 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain BLOC1_2 PF10046.9 RJW72083.1 - 1.2 9.4 5.7 2.7 8.4 0.9 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.20 RJW72083.1 - 1.9 8.5 10.4 0.57 10.2 3.6 2.4 2 0 0 2 2 2 0 Prefoldin subunit RhoGAP PF00620.27 RJW72084.1 - 1.4e-18 67.2 0.0 2.9e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain TPR_14 PF13428.6 RJW72085.1 - 2e-32 109.1 40.0 2e-05 25.0 0.4 14.6 6 5 9 16 16 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 RJW72085.1 - 1.5e-22 79.9 16.0 6.8e-08 32.9 0.3 9.1 7 4 4 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 RJW72085.1 - 1.1e-12 47.4 0.3 0.91 10.1 0.0 9.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW72085.1 - 2.7e-07 31.1 21.1 0.0034 18.0 2.6 7.5 7 2 3 10 10 9 4 Tetratricopeptide repeat Suf PF05843.14 RJW72085.1 - 5.5e-07 29.9 0.1 0.49 10.3 0.1 4.6 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_8 PF13181.6 RJW72085.1 - 1.4e-06 28.0 0.0 1.6 9.1 0.1 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat FAT PF02259.23 RJW72085.1 - 1.6e-05 24.3 5.1 1.6e-05 24.3 5.1 4.7 1 1 2 4 4 4 1 FAT domain TPR_12 PF13424.6 RJW72085.1 - 4.7e-05 23.6 15.0 0.0023 18.2 1.8 6.2 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW72085.1 - 5.2e-05 23.0 16.9 1.6 9.1 0.2 10.6 13 0 0 13 13 12 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW72085.1 - 0.00028 21.0 3.1 0.52 10.6 0.4 5.8 4 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RJW72085.1 - 0.001 18.7 0.0 0.4 10.4 0.0 4.8 4 1 1 5 5 5 1 TPR repeat TPR_4 PF07721.14 RJW72085.1 - 0.0098 16.4 4.4 4.6 8.2 0.2 5.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 RJW72085.1 - 0.016 14.9 6.3 0.3 10.8 2.1 4.1 3 2 0 3 3 3 0 Tetratricopeptide repeat-like domain Ribosomal_L31e PF01198.19 RJW72085.1 - 0.041 14.1 0.4 1.5 9.1 0.0 2.5 1 1 1 2 2 2 0 Ribosomal protein L31e SNAP PF14938.6 RJW72085.1 - 0.044 13.2 7.9 0.033 13.6 0.5 3.3 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 RJW72085.1 - 0.061 14.0 14.2 32 5.5 0.0 8.8 10 2 0 10 10 9 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 RJW72085.1 - 0.072 13.0 10.6 3 7.7 0.1 4.4 4 2 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 RJW72085.1 - 0.097 12.8 11.2 8.4 6.6 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW72085.1 - 0.1 12.5 1.3 11 6.0 0.0 5.0 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 RJW72085.1 - 5.5 7.0 8.2 1.6 8.7 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TarH PF02203.15 RJW72085.1 - 7.3 6.5 8.0 23 4.9 4.1 2.8 1 1 1 2 2 2 0 Tar ligand binding domain homologue Homeodomain PF00046.29 RJW72086.1 - 1.6e-08 34.2 0.6 3.1e-08 33.3 0.6 1.5 1 0 0 1 1 1 1 Homeodomain CBS PF00571.28 RJW72088.1 - 9.7e-36 122.0 4.0 4e-11 43.2 0.2 4.3 4 0 0 4 4 4 4 CBS domain TmoB PF06234.12 RJW72088.1 - 0.058 13.5 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) HORMA PF02301.18 RJW72090.1 - 2.6e-20 72.9 0.2 4.4e-20 72.2 0.2 1.3 1 0 0 1 1 1 1 HORMA domain zf-C2H2 PF00096.26 RJW72091.1 - 2e-07 31.1 19.4 0.011 16.1 0.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW72091.1 - 2.6e-07 30.9 20.7 0.0059 17.3 0.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.15 RJW72091.1 - 5.6e-06 26.3 17.2 0.051 13.6 1.1 3.4 2 1 1 3 3 3 3 BED zinc finger zf-H2C2_2 PF13465.6 RJW72091.1 - 3.9e-05 23.9 13.8 0.001 19.4 1.4 4.7 4 1 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 RJW72091.1 - 0.0053 17.1 8.0 0.05 14.0 0.8 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 RJW72091.1 - 0.0075 16.0 0.2 0.0075 16.0 0.2 3.3 3 1 0 3 3 2 1 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RJW72091.1 - 0.0081 15.9 15.8 0.11 12.3 0.2 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 RJW72091.1 - 0.02 15.2 16.6 0.13 12.6 0.5 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.15 RJW72091.1 - 0.044 13.7 8.2 0.76 9.7 0.0 3.4 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FCD PF07729.12 RJW72091.1 - 0.14 12.6 0.9 2.1 8.8 0.1 2.5 2 1 1 3 3 3 0 FCD domain CpXC PF14353.6 RJW72091.1 - 1.5 8.9 7.3 3.2 7.8 0.2 2.8 1 1 1 2 2 2 0 CpXC protein RecR PF02132.15 RJW72091.1 - 1.5 8.4 10.5 1.1 8.9 0.7 3.0 2 2 1 3 3 3 0 RecR protein RVT_1 PF00078.27 RJW72093.1 - 2.2e-05 24.1 0.0 3.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SeleniumBinding PF11524.8 RJW72093.1 - 0.012 16.1 0.3 7.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Selenium binding protein PlyB_C PF18684.1 RJW72093.1 - 0.034 13.9 0.3 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Pleurotolysin B C-terminal domain Imm35 PF15567.6 RJW72093.1 - 0.048 13.8 0.1 17 5.7 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 35 FerI PF08151.12 RJW72093.1 - 0.14 12.3 0.5 20 5.3 0.0 2.4 2 0 0 2 2 2 0 FerI (NUC094) domain SepZ PF06066.11 RJW72093.1 - 1.7 8.9 7.6 8.9 6.6 0.4 2.4 2 0 0 2 2 2 0 SepZ DBD_Tnp_Hermes PF10683.9 RJW72093.1 - 6.2 6.6 16.0 18 5.1 1.1 4.2 2 2 2 4 4 4 0 Hermes transposase DNA-binding domain BCIP PF13862.6 RJW72094.1 - 1.6e-20 73.7 0.0 1.9e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein P2 PF07194.11 RJW72094.1 - 0.13 12.4 0.2 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 P2 response regulator binding domain Homeodomain PF00046.29 RJW72096.1 - 4.5e-21 74.4 6.8 9.5e-21 73.4 6.8 1.6 1 0 0 1 1 1 1 Homeodomain VEFS-Box PF09733.9 RJW72097.1 - 4e-30 104.4 0.0 6.8e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein NPV_P10 PF05531.12 RJW72098.1 - 0.037 14.5 0.3 0.037 14.5 0.3 5.7 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein SEEK1 PF15357.6 RJW72098.1 - 0.13 12.4 0.5 0.4 10.8 0.2 2.0 2 0 0 2 2 2 0 Psoriasis susceptibility 1 candidate 1 DUF2935 PF11155.8 RJW72098.1 - 0.25 11.7 11.9 0.48 10.8 0.2 4.4 2 2 2 4 4 4 0 Domain of unknown function (DUF2935) ERM PF00769.19 RJW72098.1 - 0.54 10.0 0.0 0.54 10.0 0.0 5.1 2 1 2 4 4 4 0 Ezrin/radixin/moesin family Fez1 PF06818.15 RJW72098.1 - 5 7.5 76.8 1.7 9.0 18.6 4.0 1 1 2 3 3 3 0 Fez1 RVT_1 PF00078.27 RJW72099.1 - 4.6e-47 160.4 0.8 2.5e-46 158.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PCI PF01399.27 RJW72099.1 - 1.7e-13 51.0 0.0 5.9e-13 49.2 0.0 2.0 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 RJW72099.1 - 2.6e-08 33.4 0.2 6.6e-08 32.1 0.2 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix MULE PF10551.9 RJW72100.1 - 3.4e-07 30.6 0.1 7e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain Ribonuc_red_sm PF00268.21 RJW72101.1 - 1.2e-117 392.4 0.4 1.5e-117 392.1 0.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 RJW72101.1 - 0.17 12.8 0.0 0.32 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) EPO_TPO PF00758.18 RJW72102.1 - 0.044 13.8 0.2 0.074 13.1 0.1 1.4 1 1 0 1 1 1 0 Erythropoietin/thrombopoietin Cpn60_TCP1 PF00118.24 RJW72103.1 - 4.2e-125 418.2 6.3 5.1e-125 417.9 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Otopetrin PF03189.13 RJW72104.1 - 7.7e-32 110.7 31.0 1.3e-21 76.9 20.4 3.4 1 1 1 2 2 2 2 Otopetrin DUF5134 PF17197.4 RJW72104.1 - 1.9 8.3 7.2 0.48 10.3 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) BBS2_C PF14782.6 RJW72106.1 - 0.00075 18.4 0.1 0.017 13.9 0.0 2.1 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 RJW72106.1 - 0.0088 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 RJW72106.1 - 0.17 11.2 0.0 0.52 9.6 0.0 1.8 1 1 0 1 1 1 0 PTHB1 N-terminus Kinesin PF00225.23 RJW72107.1 - 3.3e-111 371.4 0.1 3.3e-111 371.4 0.1 2.7 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW72107.1 - 6.7e-26 91.0 1.0 1.8e-25 89.6 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 RJW72107.1 - 0.00021 20.3 85.7 0.0065 15.4 24.5 5.1 1 1 3 5 5 5 5 Spc7 kinetochore protein TMEM191C PF15194.6 RJW72107.1 - 0.051 13.8 0.1 0.21 11.8 0.1 2.0 1 0 0 1 1 1 0 TMEM191C family DUF4211 PF13926.6 RJW72107.1 - 3.5 7.7 12.5 6.8 6.7 0.1 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4211) MULE PF10551.9 RJW72109.1 - 8.1e-23 80.7 1.5 4.5e-10 39.8 0.1 2.4 2 0 0 2 2 2 2 MULE transposase domain DUF1203 PF06718.11 RJW72109.1 - 0.011 16.1 0.1 2.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1203) ETC_C1_NDUFA5 PF04716.14 RJW72109.1 - 0.075 12.9 0.0 17 5.3 0.0 2.3 2 0 0 2 2 2 0 ETC complex I subunit conserved region DUF3923 PF13061.6 RJW72109.1 - 0.17 12.0 0.3 29 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) ZYG-11_interact PF05884.12 RJW72109.1 - 0.18 11.2 0.0 19 4.5 0.0 2.1 2 0 0 2 2 2 0 Interactor of ZYG-11 SAM_1 PF00536.30 RJW72110.1 - 6.1e-16 58.6 3.8 5.5e-07 29.9 0.0 4.3 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RJW72110.1 - 2.8e-12 46.6 3.0 5.3e-06 26.5 0.0 3.3 4 0 0 4 4 4 2 SAM domain (Sterile alpha motif) HAUS-augmin3 PF14932.6 RJW72110.1 - 0.0088 15.7 3.8 0.014 15.0 3.8 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Tropomyosin_1 PF12718.7 RJW72110.1 - 0.085 13.0 6.7 0.14 12.3 6.7 1.2 1 0 0 1 1 1 0 Tropomyosin like Cortex-I_coil PF09304.10 RJW72110.1 - 0.12 12.6 6.8 0.34 11.1 6.8 1.8 1 0 0 1 1 1 0 Cortexillin I, coiled coil XhlA PF10779.9 RJW72110.1 - 2.8 8.2 5.2 1.3 9.3 1.4 2.1 1 1 1 2 2 2 0 Haemolysin XhlA Exo_endo_phos PF03372.23 RJW72112.1 - 0.00012 21.7 2.6 0.00026 20.6 2.5 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 RJW72112.1 - 0.0023 18.0 1.1 0.0078 16.3 1.1 2.0 1 0 0 1 1 1 1 GRF zinc finger zf-C2H2_4 PF13894.6 RJW72113.1 - 0.0024 18.5 9.9 0.054 14.4 1.6 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW72113.1 - 0.0027 18.1 11.0 0.12 12.9 1.2 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW72113.1 - 0.075 13.3 0.1 0.59 10.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_6 PF14599.6 RJW72113.1 - 0.16 12.0 0.5 2.9 8.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon DUF35_N PF12172.8 RJW72113.1 - 1.7 8.6 4.5 2.1 8.3 1.0 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf_C2H2_ZHX PF18387.1 RJW72113.1 - 2.9 7.6 5.0 1.5 8.6 0.3 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Myotub-related PF06602.14 RJW72116.1 - 1.1e-90 304.2 0.0 1.4e-90 303.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 RJW72116.1 - 0.00031 20.6 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RJW72116.1 - 0.0014 18.3 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RJW72116.1 - 0.006 16.6 0.0 0.015 15.3 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family 3-PAP PF12578.8 RJW72116.1 - 0.026 14.3 0.1 0.055 13.2 0.1 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein ArfGap PF01412.18 RJW72119.1 - 2e-38 131.1 0.0 4.1e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 RJW72119.1 - 3.8e-06 27.4 0.4 0.0032 17.9 0.1 2.5 2 0 0 2 2 2 2 PH domain Ank PF00023.30 RJW72119.1 - 4.6e-06 26.8 0.3 1.4e-05 25.3 0.3 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 RJW72119.1 - 0.00014 22.1 0.1 0.00035 20.8 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW72119.1 - 0.00027 21.4 0.2 0.00078 20.0 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PH_6 PF15406.6 RJW72119.1 - 0.0027 18.0 0.2 0.0072 16.6 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_2 PF12796.7 RJW72119.1 - 0.0029 18.2 0.1 0.0073 16.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW72119.1 - 0.039 14.5 0.0 0.14 12.8 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Ras PF00071.22 RJW72119.1 - 0.046 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Ras family PH_11 PF15413.6 RJW72119.1 - 0.11 12.9 0.8 20 5.6 0.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain HhH-GPD PF00730.25 RJW72121.1 - 2.8e-20 72.8 0.0 3.1e-19 69.4 0.0 2.2 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 RJW72121.1 - 3.4e-06 27.0 0.0 8.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 RJW72121.1 - 0.0022 17.8 0.0 0.017 15.0 0.0 2.4 3 0 0 3 3 3 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 RJW72121.1 - 0.03 14.7 2.0 0.081 13.3 2.0 1.8 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III TAF1_subA PF14929.6 RJW72123.1 - 2.9e-13 50.0 4.5 1.5e-10 41.1 0.0 2.8 3 0 0 3 3 3 2 TAF RNA Polymerase I subunit A Carn_acyltransf PF00755.20 RJW72124.1 - 1.1e-181 605.4 0.0 1.3e-181 605.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Asp PF00026.23 RJW72125.1 - 4.2e-14 52.7 0.0 4.6e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease LIM PF00412.22 RJW72126.1 - 4.2e-14 52.5 10.8 2e-09 37.6 5.4 2.3 2 0 0 2 2 2 2 LIM domain E6 PF00518.17 RJW72126.1 - 0.014 15.8 0.2 0.023 15.1 0.2 1.3 1 0 0 1 1 1 0 Early Protein (E6) C1_1 PF00130.22 RJW72126.1 - 0.14 12.1 4.6 0.1 12.5 2.5 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 RJW72126.1 - 3.3 7.9 7.5 42 4.4 0.1 3.0 1 1 2 3 3 3 0 Zinc ribbon domain VWA_2 PF13519.6 RJW72127.1 - 8e-16 58.6 0.1 6.9e-15 55.6 0.0 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 RJW72127.1 - 1.8e-11 43.1 15.5 0.0003 20.5 2.3 3.6 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 RJW72127.1 - 2e-06 27.8 0.5 3.6e-06 26.9 0.5 1.4 1 0 0 1 1 1 1 Ssl1-like RAP80_UIM PF18282.1 RJW72127.1 - 0.0023 17.7 2.3 0.0023 17.7 2.3 2.4 2 0 0 2 2 2 1 RAP80 N-terminal ubiquitin interaction motif ACPS PF01648.20 RJW72128.1 - 5.9e-19 68.3 0.0 9.5e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily AAA_assoc_C PF09821.9 RJW72129.1 - 0.13 12.8 0.5 0.22 12.1 0.5 1.5 1 1 0 1 1 1 0 C-terminal AAA-associated domain Myb_DNA-bind_4 PF13837.6 RJW72129.1 - 0.69 10.3 3.8 3.8 8.0 0.0 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Peptidase_M13_N PF05649.13 RJW72131.1 - 3e-49 168.7 7.8 5.4e-49 167.9 7.8 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RJW72131.1 - 1.5e-18 67.1 0.5 4.8e-18 65.5 0.1 2.1 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 RJW72132.1 - 3.6e-46 158.6 1.5 6.4e-46 157.8 1.5 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RJW72132.1 - 8.8e-21 74.5 0.0 2.1e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M13 DUF1854 PF08909.11 RJW72132.1 - 0.16 11.8 0.3 0.38 10.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) DUF3951 PF13131.6 RJW72132.1 - 0.18 12.0 2.8 0.54 10.5 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) p450 PF00067.22 RJW72133.1 - 7.2e-05 21.7 0.0 0.00023 20.0 0.0 1.7 1 1 0 2 2 2 1 Cytochrome P450 His_Phos_2 PF00328.22 RJW72134.1 - 3.9e-19 69.3 0.1 8.8e-16 58.2 0.1 2.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) WD40 PF00400.32 RJW72136.1 - 1.9e-34 117.1 23.9 8.9e-06 26.4 0.3 8.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 RJW72136.1 - 2e-19 69.2 2.3 3.6e-19 68.4 2.3 1.4 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 RJW72136.1 - 2.9e-06 27.5 0.1 0.086 13.1 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW72136.1 - 1.6e-05 23.8 4.2 0.37 9.4 0.1 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 RJW72136.1 - 3e-05 23.5 0.0 0.098 12.0 0.0 2.4 1 1 0 2 2 2 2 WD40-like domain F-box-like PF12937.7 RJW72136.1 - 0.00019 21.2 2.3 0.00024 20.9 0.9 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RJW72136.1 - 0.0017 18.2 0.6 0.013 15.3 0.2 2.4 2 0 0 2 2 2 1 F-box domain FAD_binding_2 PF00890.24 RJW72138.1 - 6.6e-127 424.0 2.7 9.1e-127 423.6 2.7 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 RJW72138.1 - 8.1e-39 132.5 0.0 1.2e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 RJW72138.1 - 2.8e-06 26.8 0.1 0.0061 15.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 RJW72138.1 - 2.3e-05 23.7 1.8 0.009 15.1 2.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 RJW72138.1 - 3.5e-05 23.2 0.4 0.0004 19.7 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RJW72138.1 - 0.021 14.1 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 RJW72138.1 - 0.032 12.9 0.1 0.23 10.1 0.1 2.4 4 0 0 4 4 4 0 HI0933-like protein DAO PF01266.24 RJW72138.1 - 0.052 13.1 0.6 0.088 12.4 0.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase LisH PF08513.11 RJW72139.1 - 0.058 13.4 0.9 0.26 11.3 0.0 2.5 2 0 0 2 2 2 0 LisH YabA PF06156.13 RJW72139.1 - 0.2 12.3 0.3 0.39 11.4 0.3 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Rab15_effector PF15208.6 RJW72140.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Rab15 effector RVT_1 PF00078.27 RJW72141.1 - 8.2e-11 41.8 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_carr PF00153.27 RJW72143.1 - 9.2e-59 195.4 4.4 1.4e-18 66.6 0.3 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 RJW72144.1 - 0.00033 20.5 0.9 0.0013 18.6 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RJW72144.1 - 0.00067 19.5 2.7 0.0013 18.5 1.1 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 RJW72144.1 - 0.015 15.2 0.2 0.044 13.7 0.2 1.8 1 0 0 1 1 1 0 F-box PRANC PF09372.10 RJW72144.1 - 0.19 12.1 0.0 0.55 10.6 0.0 1.8 1 0 0 1 1 1 0 PRANC domain FSA_C PF10479.9 RJW72145.1 - 0.21 9.7 0.0 0.21 9.7 0.0 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ribosomal_L35Ae PF01247.18 RJW72146.1 - 7.8e-45 151.0 1.2 9.8e-45 150.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 RJW72146.1 - 0.0081 16.4 0.1 5.1 7.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Adap_comp_sub PF00928.21 RJW72147.1 - 1.4e-60 204.9 0.0 1.5e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 RJW72147.1 - 0.016 14.7 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain F-box-like PF12937.7 RJW72148.1 - 1.9e-11 43.7 0.4 8.5e-11 41.6 0.4 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RJW72148.1 - 8.8e-10 38.2 0.1 4.3e-09 36.0 0.1 2.3 1 0 0 1 1 1 1 F-box domain RVT_1 PF00078.27 RJW72148.1 - 0.0002 20.9 0.1 0.00056 19.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box_4 PF15966.5 RJW72148.1 - 0.00038 20.3 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 F-box LRR_6 PF13516.6 RJW72148.1 - 0.044 13.8 21.7 2.7 8.3 0.1 8.2 10 0 0 10 10 10 0 Leucine Rich repeat LRR_1 PF00560.33 RJW72148.1 - 0.35 11.6 19.7 8.1 7.4 0.2 7.5 7 0 0 7 7 7 0 Leucine Rich Repeat Hep_core_N PF08290.11 RJW72148.1 - 6.2 6.9 8.1 12 6.0 0.1 4.0 3 0 0 3 3 3 0 Hepatitis core protein, putative zinc finger LRR_4 PF12799.7 RJW72148.1 - 8.4 7.0 17.2 3 8.4 0.2 6.6 6 3 4 10 10 10 0 Leucine Rich repeats (2 copies) Clat_adaptor_s PF01217.20 RJW72149.1 - 7.7e-10 38.9 0.4 1.2e-09 38.2 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.21 RJW72149.1 - 4.7e-07 29.4 0.0 8.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pkinase PF00069.25 RJW72150.1 - 3.3e-48 164.4 0.0 7.4e-48 163.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72150.1 - 3.8e-23 82.1 0.0 7.9e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 RJW72150.1 - 1e-11 44.5 5.9 3.5e-11 42.8 5.9 1.9 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 RJW72150.1 - 4.2e-10 39.4 0.0 9.5e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like C1_2 PF03107.16 RJW72150.1 - 0.042 14.2 4.3 0.13 12.6 4.3 1.9 1 0 0 1 1 1 0 C1 domain APH PF01636.23 RJW72150.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF4665 PF15679.5 RJW72150.1 - 0.45 11.2 4.4 2.1 9.0 4.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) ATG16 PF08614.11 RJW72150.1 - 5.8 7.1 57.9 1.1 9.4 11.3 4.4 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) TBCA PF02970.16 RJW72152.1 - 3.2e-20 72.2 4.9 3.6e-20 72.1 4.9 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A zf-RING_UBOX PF13445.6 RJW72153.1 - 3.1e-08 33.5 2.9 3.1e-08 33.5 2.9 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RJW72153.1 - 2.8e-07 30.6 5.3 2.7e-06 27.4 5.3 2.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 RJW72153.1 - 5.5e-07 29.3 2.6 5.5e-07 29.3 2.6 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RJW72153.1 - 7.7e-06 25.8 3.5 7.7e-06 25.8 3.5 2.8 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RJW72153.1 - 2.6e-05 24.0 3.5 2.6e-05 24.0 3.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW72153.1 - 0.00031 21.0 5.7 0.00031 21.0 5.7 2.6 2 0 0 2 2 2 1 Ring finger domain CK_II_beta PF01214.18 RJW72153.1 - 0.013 15.3 0.8 0.024 14.5 0.8 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Prok-RING_4 PF14447.6 RJW72153.1 - 0.097 12.5 12.6 0.19 11.6 7.8 3.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RJW72153.1 - 0.96 9.8 6.3 0.6 10.4 2.9 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 RJW72153.1 - 2.2 8.1 10.3 0.063 13.1 3.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain MtrB PF05440.12 RJW72154.1 - 0.039 14.4 0.2 4.2 7.8 0.0 2.6 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Laminin_II PF06009.12 RJW72154.1 - 0.048 13.7 5.3 0.062 13.3 2.2 2.2 1 1 1 2 2 2 0 Laminin Domain II Nnf1 PF03980.14 RJW72154.1 - 0.05 14.0 2.3 0.27 11.7 0.5 2.1 2 0 0 2 2 2 0 Nnf1 Ax_dynein_light PF10211.9 RJW72154.1 - 0.054 13.4 3.8 2.8 7.9 0.0 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain TPALS PF18178.1 RJW72154.1 - 0.085 12.3 0.2 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 TIR- and PNP-associating SLOG family DUF1204 PF06721.11 RJW72154.1 - 0.09 12.2 1.6 0.12 11.8 1.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1204) CENP-H PF05837.12 RJW72154.1 - 0.41 11.1 7.6 0.41 11.1 3.8 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF1043 PF06295.12 RJW72154.1 - 1 9.4 4.9 2.4 8.2 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) ADIP PF11559.8 RJW72154.1 - 3.3 7.8 10.0 2.7 8.1 0.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GTP_cyclohydroI PF01227.22 RJW72158.1 - 0.048 13.1 0.1 0.053 12.9 0.1 1.0 1 0 0 1 1 1 0 GTP cyclohydrolase I RNA_pol_Rpa2_4 PF06883.12 RJW72158.1 - 0.16 12.0 0.0 0.82 9.7 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain WH1 PF00568.23 RJW72159.1 - 1.5e-17 63.5 0.0 2.1e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 RJW72159.1 - 1.1e-06 28.8 0.0 3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Thymosin PF01290.20 RJW72159.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Thymosin beta-4 family NAD_binding_1 PF00175.21 RJW72160.1 - 3.5e-31 108.1 0.0 1.3e-30 106.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RJW72160.1 - 3.1e-27 94.8 0.0 5.1e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 RJW72160.1 - 2.8e-05 24.3 0.0 0.0053 16.9 0.0 2.9 3 0 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 RJW72160.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF4485 PF14846.6 RJW72162.1 - 0.096 12.7 0.0 0.19 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) CEP44 PF15007.6 RJW72163.1 - 4.2e-24 85.1 0.1 7.1e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 RVT_1 PF00078.27 RJW72164.1 - 5.2e-45 153.7 0.0 9.6e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fic PF02661.18 RJW72164.1 - 3.8e-25 88.6 0.0 1.1e-24 87.1 0.0 1.9 1 0 0 1 1 1 1 Fic/DOC family Exo_endo_phos PF03372.23 RJW72164.1 - 0.00024 20.7 0.6 0.0005 19.7 0.6 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_2 PF07719.17 RJW72164.1 - 0.011 15.8 0.7 0.089 13.0 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 RJW72164.1 - 0.2 11.4 0.1 0.45 10.2 0.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.6 RJW72164.1 - 1.9 9.5 8.8 0.18 12.7 1.7 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HipN PF18253.1 RJW72166.1 - 2.3e-19 68.8 1.8 3.6e-19 68.2 0.2 2.3 3 0 0 3 3 3 1 Hsp70-interacting protein N N-terminal domain TPR_1 PF00515.28 RJW72166.1 - 2e-15 55.9 0.4 4.5e-05 23.1 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RJW72166.1 - 1.8e-14 52.6 0.9 0.00093 19.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat STI1 PF17830.1 RJW72166.1 - 1.6e-11 43.9 0.8 3.9e-11 42.7 0.8 1.7 1 0 0 1 1 1 1 STI1 domain TPR_11 PF13414.6 RJW72166.1 - 1.6e-10 40.5 0.0 0.0003 20.4 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 RJW72166.1 - 5.3e-08 32.9 0.0 8.5e-06 25.8 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RJW72166.1 - 3e-07 30.1 0.3 0.017 15.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW72166.1 - 1.2e-06 28.5 0.2 0.08 13.4 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW72166.1 - 2.5e-05 24.7 0.1 0.00069 20.1 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RJW72166.1 - 2.9e-05 24.6 0.1 0.0012 19.5 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW72166.1 - 5.6e-05 23.6 1.0 0.0024 18.5 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW72166.1 - 0.021 15.1 0.2 5.3 7.4 0.0 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW72166.1 - 0.034 14.2 0.0 14 6.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RJW72166.1 - 0.08 13.6 0.1 4.3 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ZnuA PF01297.17 RJW72166.1 - 0.65 9.4 3.0 0.95 8.8 2.5 1.5 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Tfb2 PF03849.14 RJW72167.1 - 3.5e-117 391.4 0.0 4e-117 391.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 RJW72167.1 - 1.6e-27 95.7 1.1 4.6e-27 94.2 0.7 2.0 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 RJW72167.1 - 0.0095 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RIIa PF02197.17 RJW72167.1 - 0.097 12.4 0.1 6.7 6.5 0.1 2.6 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Ank_5 PF13857.6 RJW72169.1 - 4.4e-22 77.9 8.9 4.4e-11 42.8 0.7 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW72169.1 - 1.5e-21 76.8 2.1 2e-12 47.5 0.5 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW72169.1 - 1.3e-19 70.3 14.9 3.5e-10 40.2 0.5 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RJW72169.1 - 6.9e-18 64.2 11.8 3.3e-06 27.3 0.6 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 RJW72169.1 - 3e-14 51.7 4.0 0.00013 22.1 0.3 5.0 5 0 0 5 5 5 4 Ankyrin repeat Pkinase PF00069.25 RJW72171.1 - 2.7e-66 223.6 0.0 4.7e-66 222.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72171.1 - 3e-29 102.1 0.0 5.8e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW72171.1 - 5e-05 22.8 0.0 8.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RJW72171.1 - 0.00069 18.7 0.8 0.0016 17.5 0.8 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RJW72171.1 - 0.024 14.0 0.3 0.05 12.9 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BK_channel_a PF03493.18 RJW72172.1 - 2.9e-29 101.1 0.0 6.7e-16 58.3 0.0 2.6 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 RJW72172.1 - 4.2e-19 68.8 13.9 4.2e-19 68.8 13.9 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 RJW72172.1 - 2.4e-14 53.0 6.0 2.4e-14 53.0 6.0 2.4 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 RJW72172.1 - 0.033 14.5 0.2 0.07 13.4 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain zf-met PF12874.7 RJW72173.1 - 2e-06 28.0 3.7 0.036 14.5 1.5 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 RJW72173.1 - 1.8e-05 25.0 0.3 1.8e-05 25.0 0.3 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW72173.1 - 0.0001 22.8 14.1 0.00035 21.1 1.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW72173.1 - 0.0013 19.0 12.3 0.03 14.8 1.2 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW72173.1 - 0.0052 17.0 1.0 0.028 14.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RJW72173.1 - 0.14 12.5 3.6 1.3 9.4 0.3 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 RJW72173.1 - 0.22 11.6 7.8 0.12 12.4 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 RJW72173.1 - 0.64 10.4 4.2 1.5 9.1 4.2 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 RJW72173.1 - 1.1 9.3 8.7 0.19 11.8 1.6 2.6 1 1 1 2 2 2 0 BED zinc finger Proteasome PF00227.26 RJW72176.1 - 6e-30 104.2 0.0 7.3e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit GFD1 PF17331.2 RJW72176.1 - 0.2 11.9 0.8 0.45 10.8 0.2 1.8 2 0 0 2 2 2 0 GFD1 mRNA transport factor DASH_Dad4 PF08650.10 RJW72178.1 - 0.012 15.5 1.6 0.019 15.0 0.2 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad4 GIY-YIG PF01541.24 RJW72178.1 - 0.62 10.4 4.8 2.4 8.5 0.2 2.7 2 1 0 2 2 2 0 GIY-YIG catalytic domain RRM_1 PF00076.22 RJW72180.1 - 2.4e-17 62.5 0.1 2.3e-10 40.2 0.1 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vps4_C PF09336.10 RJW72180.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain DUF4817 PF16087.5 RJW72182.1 - 1e-13 50.9 0.0 1.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_IclR PF09339.10 RJW72182.1 - 0.001 18.8 1.0 0.0023 17.7 0.3 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 RJW72182.1 - 0.11 11.9 0.1 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 RJW72182.1 - 0.12 12.2 0.1 6.2 6.8 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain Phage_antitermQ PF06530.12 RJW72182.1 - 0.22 11.4 0.7 22 5.0 0.0 3.3 3 1 1 4 4 4 0 Phage antitermination protein Q Tom37 PF10568.9 RJW72183.1 - 2.3e-16 60.2 0.0 4.7e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 RJW72183.1 - 4.9e-15 55.1 1.2 1.2e-13 50.6 1.2 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RJW72183.1 - 6.9e-07 29.9 0.0 1.2e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 RJW72183.1 - 0.00051 20.0 0.7 0.0012 18.8 0.7 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-His_Me_endon PF05551.11 RJW72184.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease CDC37_M PF08565.11 RJW72185.1 - 2.9e-23 82.0 1.3 6.8e-23 80.8 0.1 2.2 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 RJW72185.1 - 4e-15 56.9 15.9 9e-15 55.7 14.4 2.3 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 RJW72185.1 - 4.9e-15 55.5 4.1 6.6e-15 55.1 0.0 2.8 2 1 0 2 2 2 1 Cdc37 C terminal domain FliD_C PF07195.12 RJW72185.1 - 0.03 13.8 2.1 4.5 6.6 0.4 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus UBM PF14377.6 RJW72185.1 - 0.07 12.6 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin binding region Cadherin PF00028.17 RJW72187.1 - 1.4e-41 140.9 13.5 3.2e-10 40.3 0.1 9.0 7 2 1 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 RJW72187.1 - 8.1e-11 41.6 0.0 2.5e-07 30.4 0.0 3.7 3 0 0 3 3 3 2 Cadherin-like Cadherin_3 PF16184.5 RJW72187.1 - 4.4e-06 26.7 11.7 0.39 10.7 0.1 5.7 5 1 0 5 5 5 4 Cadherin-like Ctr PF04145.15 RJW72188.1 - 1.5e-29 103.5 0.0 2e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF4229 PF14012.6 RJW72188.1 - 0.17 12.0 6.4 0.067 13.3 3.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) YlaC PF10777.9 RJW72188.1 - 0.56 10.0 3.9 0.81 9.5 3.9 1.2 1 0 0 1 1 1 0 Inner membrane protein YlaC muHD PF10291.9 RJW72189.1 - 1.1e-13 51.3 0.0 2.6e-12 46.7 0.0 2.8 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 RJW72189.1 - 5e-11 42.7 3.4 5.9e-11 42.5 0.1 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5426 PF17473.2 RJW72189.1 - 0.0093 16.2 0.7 0.019 15.2 0.7 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5426) AKAP7_RIRII_bdg PF10470.9 RJW72189.1 - 0.082 13.0 0.4 0.22 11.6 0.4 1.6 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein RIG-I_C PF18119.1 RJW72189.1 - 8.2 6.4 11.9 0.27 11.3 1.5 2.6 1 1 1 2 2 2 0 RIG-I receptor C-terminal domain DUF2408 PF10303.9 RJW72191.1 - 0.0075 16.8 2.4 0.008 16.7 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2408) PXA PF02194.15 RJW72191.1 - 1.9 8.5 5.6 1.6 8.7 1.4 2.1 2 0 0 2 2 2 0 PXA domain 7tm_1 PF00001.21 RJW72192.1 - 5.1e-14 52.2 9.5 8e-14 51.6 9.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2834 PF11196.8 RJW72192.1 - 0.73 10.2 8.1 0.54 10.6 4.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) UCH PF00443.29 RJW72194.1 - 2.6e-19 69.7 0.0 1.7e-18 67.1 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW72194.1 - 7.3e-13 48.8 0.1 1.6e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RJW72194.1 - 1.7e-06 27.7 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 RJW72194.1 - 0.0004 20.9 0.0 2.6 8.7 0.0 3.5 3 0 0 3 3 3 2 DUSP domain PBC PF03792.13 RJW72195.1 - 2.9e-81 271.8 0.0 4e-81 271.3 0.0 1.2 1 0 0 1 1 1 1 PBC domain Homeodomain PF00046.29 RJW72195.1 - 5.1e-20 71.1 0.5 1.2e-19 69.9 0.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW72195.1 - 4.3e-16 58.5 0.1 1.7e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain Nucleoporin_FG2 PF15967.5 RJW72195.1 - 0.00073 18.2 0.0 0.0014 17.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin FG repeated region YdaS_antitoxin PF15943.5 RJW72195.1 - 0.0014 18.5 0.1 0.003 17.4 0.1 1.5 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 RJW72195.1 - 0.0068 16.4 0.0 0.022 14.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix CENP-B_N PF04218.13 RJW72195.1 - 0.091 12.4 0.0 0.35 10.5 0.0 2.0 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain LIM PF00412.22 RJW72196.1 - 1.2e-26 92.7 16.4 8.3e-13 48.4 10.4 2.2 2 0 0 2 2 2 2 LIM domain DZR PF12773.7 RJW72196.1 - 0.97 9.5 15.3 1.6e+03 -0.8 14.9 3.5 1 1 0 1 1 1 0 Double zinc ribbon TPR_12 PF13424.6 RJW72199.1 - 8.6e-10 38.8 0.3 5.3e-08 33.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RJW72199.1 - 1.9e-06 27.6 3.1 0.037 13.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW72199.1 - 3.2e-06 26.9 0.3 0.13 12.5 0.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW72199.1 - 2.4e-05 24.1 2.3 0.19 11.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RJW72199.1 - 0.00073 19.3 0.3 1 9.3 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW72199.1 - 0.0047 16.9 1.2 5.5 7.3 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 RJW72199.1 - 0.14 11.6 0.5 0.46 10.0 0.1 2.1 2 0 0 2 2 2 0 SHNi-TPR Cadherin PF00028.17 RJW72200.1 - 7.5e-21 74.4 0.0 4.5e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 Cadherin domain Cadherin_2 PF08266.12 RJW72200.1 - 0.019 14.8 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Cadherin-like RVT_1 PF00078.27 RJW72202.1 - 1.3e-44 152.4 0.0 2e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Clathrin PF00637.20 RJW72202.1 - 1.3e-12 47.8 0.3 3.4e-09 36.7 0.0 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS Exo_endo_phos_2 PF14529.6 RJW72202.1 - 6.3e-07 29.3 0.0 2.2e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW72202.1 - 1e-06 28.4 1.0 2.6e-06 27.1 0.4 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Vps39_1 PF10366.9 RJW72202.1 - 0.0094 16.2 0.0 2.5 8.4 0.0 2.6 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 1 Fez1 PF06818.15 RJW72203.1 - 0.0022 18.5 13.1 0.0022 18.5 13.1 2.8 2 1 1 3 3 3 2 Fez1 DivIC PF04977.15 RJW72203.1 - 0.012 15.4 0.7 0.012 15.4 0.7 3.5 3 1 0 3 3 3 0 Septum formation initiator CorA PF01544.18 RJW72203.1 - 0.72 9.1 9.8 1.2 8.4 9.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Seryl_tRNA_N PF02403.22 RJW72203.1 - 1.8 8.8 18.2 1.6 9.0 8.9 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.8 RJW72203.1 - 2.2 8.4 25.8 1.3 9.1 14.8 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 RJW72203.1 - 2.4 8.0 18.7 0.5 10.2 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GAS PF13851.6 RJW72203.1 - 3.4 6.9 33.8 0.027 13.8 4.5 3.6 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.6 RJW72203.1 - 4.7 7.7 18.8 1.2 9.6 3.2 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Golgin_A5 PF09787.9 RJW72203.1 - 6.4 6.1 28.3 0.8 9.1 24.2 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 Bacillus_HBL PF05791.11 RJW72203.1 - 7.6 6.3 13.7 11 5.9 1.3 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF384 PF04064.13 RJW72204.1 - 2.7e-19 68.8 0.1 2.7e-19 68.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF383 PF04063.14 RJW72204.1 - 3.2e-15 56.3 0.3 2.4e-14 53.4 0.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF383) NP1-WLL PF11733.8 RJW72204.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Non-capsid protein NP1 Atx10homo_assoc PF09759.9 RJW72204.1 - 0.21 11.6 0.9 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain E1_DerP2_DerF2 PF02221.15 RJW72205.1 - 2.4e-23 83.0 0.2 3e-23 82.7 0.2 1.1 1 0 0 1 1 1 1 ML domain LRR_8 PF13855.6 RJW72206.1 - 7.6e-05 22.4 0.1 0.00049 19.8 0.0 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 RJW72206.1 - 0.026 14.9 3.6 0.57 10.7 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) AAA_6 PF12774.7 RJW72206.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region MFS_1 PF07690.16 RJW72207.1 - 2.7e-24 85.8 62.4 1.5e-21 76.7 35.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FSAP_sig_propep PF03032.15 RJW72207.1 - 0.076 13.0 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide DNA_photolyase PF00875.18 RJW72208.1 - 9.7e-15 54.9 0.0 4.6e-14 52.8 0.0 2.1 2 1 0 2 2 2 1 DNA photolyase Acetyltransf_1 PF00583.25 RJW72209.1 - 1.7e-13 50.8 0.0 2.4e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RJW72209.1 - 5.5e-09 36.0 0.0 9.1e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RJW72209.1 - 5.1e-08 33.2 0.2 8.9e-08 32.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RJW72209.1 - 8.1e-06 26.1 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 RJW72209.1 - 0.00024 20.8 0.0 0.00043 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RJW72209.1 - 0.0048 16.8 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 RJW72209.1 - 0.034 14.8 0.0 0.044 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX PF00293.28 RJW72211.1 - 0.0041 17.2 0.0 0.09 12.8 0.1 2.5 2 1 0 2 2 2 1 NUDIX domain GIY-YIG PF01541.24 RJW72212.1 - 0.052 13.8 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain vMSA PF00695.19 RJW72213.1 - 0.072 12.2 0.8 0.069 12.2 0.8 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PHD PF00628.29 RJW72214.1 - 0.0049 16.7 0.6 0.0049 16.7 0.6 2.0 2 0 0 2 2 2 1 PHD-finger Myc_N PF01056.18 RJW72214.1 - 0.035 14.0 3.4 0.051 13.5 3.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Apt1 PF10351.9 RJW72214.1 - 0.13 11.0 6.5 0.17 10.7 6.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Apidaecin PF00807.17 RJW72214.1 - 0.59 10.3 7.8 6.5 6.9 0.7 2.6 2 0 0 2 2 2 0 Apidaecin PBP1_TM PF14812.6 RJW72214.1 - 1.7 9.1 11.5 0.27 11.6 7.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EMC1_C PF07774.13 RJW72215.1 - 3.4e-61 206.6 0.6 3.2e-60 203.4 0.6 2.3 1 1 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 RJW72215.1 - 0.0031 17.1 0.0 0.41 10.2 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain zf-C2H2 PF00096.26 RJW72218.1 - 8.8e-15 54.2 30.1 0.0008 19.7 1.0 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW72218.1 - 2.8e-11 43.3 29.8 0.0056 17.4 0.3 5.6 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW72218.1 - 6.5e-10 39.0 28.3 0.014 15.8 2.2 5.9 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 RJW72218.1 - 1.4e-09 37.7 26.3 2.6e-06 27.3 5.3 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW72218.1 - 1.8e-08 34.5 22.1 0.01 16.1 0.2 4.7 3 1 1 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW72218.1 - 1.1e-05 25.6 19.2 0.0086 16.4 0.1 5.2 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RJW72218.1 - 0.00088 19.5 3.6 0.00088 19.5 3.6 4.1 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 RJW72218.1 - 0.15 11.9 4.4 0.23 11.3 0.5 3.2 2 1 0 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.7 RJW72218.1 - 0.26 11.6 14.2 1.1 9.6 0.0 4.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2225 PF09986.9 RJW72218.1 - 0.27 10.9 4.4 11 5.7 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn-C2H2_12 PF18112.1 RJW72218.1 - 0.63 10.6 4.8 5 7.7 0.1 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain PyrI_C PF02748.15 RJW72218.1 - 2.2 8.3 10.0 8.8 6.3 0.0 4.0 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 RJW72218.1 - 8.2 7.3 7.3 9.7 7.0 1.4 3.3 2 1 1 3 3 3 0 zinc-ribbon family ELM2 PF01448.24 RJW72219.1 - 7e-10 39.5 1.0 1.3e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 RJW72219.1 - 1.1e-06 28.7 0.1 2.4e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_6 PF13912.6 RJW72219.1 - 0.0083 16.1 2.8 0.022 14.8 2.8 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger Myb_DNA-bind_6 PF13921.6 RJW72219.1 - 0.016 15.4 0.1 0.036 14.3 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 RJW72219.1 - 0.021 15.6 4.7 0.053 14.4 4.7 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Myb_DNA-bind_7 PF15963.5 RJW72219.1 - 0.024 14.5 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 Myb DNA-binding like zf-C2H2 PF00096.26 RJW72219.1 - 0.032 14.7 5.0 0.088 13.3 5.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RJW72219.1 - 0.092 13.1 1.3 0.22 11.9 1.3 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Kunitz_BPTI PF00014.23 RJW72222.1 - 0.035 14.4 0.0 0.073 13.3 0.0 1.5 1 1 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain TspO_MBR PF03073.15 RJW72223.1 - 8.5e-41 139.2 13.2 1e-40 138.9 13.2 1.0 1 0 0 1 1 1 1 TspO/MBR family Haem_degrading PF03928.14 RJW72224.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Haem-degrading Rogdi_lz PF10259.9 RJW72224.1 - 0.23 10.9 2.3 0.53 9.7 0.1 2.3 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein DUF4064 PF13273.6 RJW72224.1 - 0.89 9.9 7.0 4.2 7.7 3.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) ADH_zinc_N_2 PF13602.6 RJW72225.1 - 6.1e-13 50.0 0.0 2.5e-12 48.0 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RJW72225.1 - 7e-12 45.2 0.5 7e-12 45.2 0.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RJW72225.1 - 1.6e-09 37.8 0.0 3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3898 PF13037.6 RJW72225.1 - 0.13 12.4 0.1 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3898) BROMI PF14961.6 RJW72226.1 - 4.5e-122 408.7 4.9 1.1e-42 145.8 0.0 4.1 4 0 0 4 4 4 4 Broad-minded protein RabGAP-TBC PF00566.18 RJW72226.1 - 0.0079 15.9 0.6 0.017 14.8 0.6 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2664 PF10867.8 RJW72226.1 - 0.1 13.0 0.2 0.33 11.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) TspO_MBR PF03073.15 RJW72227.1 - 3.7e-36 124.1 14.4 3.7e-36 124.1 14.4 1.5 1 1 0 1 1 1 1 TspO/MBR family Glyco_hydro_20 PF00728.22 RJW72231.1 - 5e-72 243.2 0.2 4.6e-71 240.1 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 RJW72231.1 - 1.3e-08 35.6 0.0 2.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 RJW72231.1 - 0.011 16.5 0.0 0.019 15.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 GHL6 PF14871.6 RJW72231.1 - 0.016 15.4 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 DUF898 PF05987.13 RJW72231.1 - 0.11 11.6 1.6 0.19 10.7 1.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) YL1 PF05764.13 RJW72232.1 - 1.2e-39 136.9 23.4 1.6e-39 136.5 23.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 RJW72232.1 - 3.3e-13 49.1 0.2 7.5e-13 48.0 0.2 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Tmemb_55A PF09788.9 RJW72233.1 - 1.4e-52 178.2 17.7 1.9e-35 122.2 9.5 2.1 2 0 0 2 2 2 2 Transmembrane protein 55A IBR PF01485.21 RJW72233.1 - 0.0074 16.5 14.5 0.067 13.4 0.2 4.2 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain HypA PF01155.19 RJW72233.1 - 0.036 14.1 0.9 0.036 14.1 0.9 3.1 4 1 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 RJW72233.1 - 0.3 11.2 10.7 0.63 10.1 4.4 3.3 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_9 PF14369.6 RJW72233.1 - 3.9 7.8 12.4 12 6.3 3.3 3.8 3 0 0 3 3 3 0 zinc-ribbon zinc_ribbon_4 PF13717.6 RJW72233.1 - 5.4 7.0 22.8 4.4 7.3 4.4 5.1 5 1 1 6 6 6 0 zinc-ribbon domain PLAC8 PF04749.17 RJW72234.1 - 6.9e-11 43.0 9.7 9.9e-11 42.5 9.7 1.2 1 0 0 1 1 1 1 PLAC8 family LEP503 PF15221.6 RJW72234.1 - 2.4 8.5 6.5 1.9 8.9 0.3 2.2 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 Thiolase_N PF00108.23 RJW72235.1 - 3.7e-51 174.0 0.3 5.2e-51 173.5 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RJW72235.1 - 7.5e-38 128.9 2.6 9.9e-38 128.6 0.9 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RJW72235.1 - 0.00073 19.2 0.8 0.002 17.7 0.8 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF4447 PF14590.6 RJW72235.1 - 0.077 12.8 0.1 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4447) CAP PF00188.26 RJW72236.1 - 2.6e-20 73.6 0.2 3.2e-20 73.3 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Histone PF00125.24 RJW72237.1 - 8.3e-09 35.9 1.4 1.1e-08 35.5 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 EF-hand_6 PF13405.6 RJW72238.1 - 1e-07 31.3 0.2 0.0026 17.6 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RJW72238.1 - 2.3e-07 30.0 0.2 0.0029 17.0 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 RJW72238.1 - 5.3e-07 28.7 1.0 0.00058 19.2 0.1 2.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RJW72238.1 - 1.5e-06 28.6 0.1 2.1e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RJW72238.1 - 0.00036 20.3 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_like PF09279.11 RJW72238.1 - 0.013 16.0 0.0 0.033 14.7 0.0 1.7 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like EspA PF03433.13 RJW72238.1 - 0.08 12.8 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 EspA-like secreted protein DUF5109 PF17134.4 RJW72238.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) Histone PF00125.24 RJW72239.1 - 3.5e-28 98.6 0.7 5.2e-28 98.0 0.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 RJW72239.1 - 0.043 14.4 3.7 0.061 13.9 2.4 1.9 2 0 0 2 2 2 0 PCNA-associated factor histone like domain adh_short PF00106.25 RJW72240.1 - 2.8e-41 141.1 0.0 3.4e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW72240.1 - 6.5e-27 94.6 0.0 8.4e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW72240.1 - 0.006 16.5 0.1 0.023 14.6 0.1 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 RJW72240.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 RJW72240.1 - 0.059 13.5 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ASF1_hist_chap PF04729.13 RJW72241.1 - 1e-64 217.2 0.1 8.3e-63 210.9 0.1 2.1 1 1 0 1 1 1 1 ASF1 like histone chaperone Lig_chan PF00060.26 RJW72242.1 - 3.3e-29 101.6 0.4 5.4e-29 101.0 0.4 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RJW72242.1 - 3e-23 82.2 0.0 3.6e-21 75.5 0.0 2.3 2 0 0 2 2 2 2 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RJW72242.1 - 1.3e-21 77.1 0.0 7.1e-21 74.7 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peptidase_S29 PF02907.15 RJW72243.1 - 0.0043 16.8 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease VHL PF01847.16 RJW72243.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 VHL beta domain EF-hand_1 PF00036.32 RJW72245.1 - 3e-23 79.6 9.3 1.6e-07 30.4 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW72245.1 - 5.4e-22 78.0 9.8 1.6e-12 47.7 1.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW72245.1 - 6.5e-19 66.2 9.9 2.9e-05 23.7 0.1 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RJW72245.1 - 1.5e-18 65.4 7.6 5.1e-06 25.7 0.3 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RJW72245.1 - 7.2e-15 54.6 7.6 6.7e-06 25.9 0.2 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_10 PF14788.6 RJW72245.1 - 9.4e-06 25.4 5.1 0.039 13.8 0.1 3.5 3 1 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 RJW72245.1 - 4.7e-05 23.3 3.1 0.44 10.5 0.2 3.0 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RJW72245.1 - 0.00013 22.3 6.0 0.0066 16.7 0.5 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 RJW72245.1 - 0.0055 16.6 1.4 4.4 7.2 0.0 3.2 2 1 2 4 4 4 2 Caleosin related protein DUF1456 PF07308.13 RJW72245.1 - 0.017 15.5 3.6 0.28 11.5 0.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1456) EF-hand_11 PF08976.11 RJW72245.1 - 0.025 15.4 1.1 6.2 7.7 0.2 2.9 1 1 1 3 3 3 0 EF-hand domain p25-alpha PF05517.12 RJW72245.1 - 0.032 14.4 7.7 0.088 13.0 0.6 2.5 1 1 1 2 2 2 0 p25-alpha HTH_37 PF13744.6 RJW72245.1 - 0.045 13.7 0.1 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain FBA_2 PF07735.17 RJW72245.1 - 0.098 12.8 1.1 0.22 11.6 0.4 1.9 2 0 0 2 2 2 0 F-box associated Sars6 PF12133.8 RJW72245.1 - 0.12 12.3 0.1 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus S_100 PF01023.19 RJW72245.1 - 4.9 6.9 8.7 6 6.7 0.8 3.9 4 1 1 5 5 5 0 S-100/ICaBP type calcium binding domain DER1 PF04511.15 RJW72246.1 - 3.1e-31 108.8 11.7 3.7e-31 108.6 11.7 1.1 1 0 0 1 1 1 1 Der1-like family EF-hand_1 PF00036.32 RJW72247.1 - 1.1e-16 59.1 0.1 9.5e-05 21.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW72247.1 - 1.5e-15 57.4 1.0 2.8e-07 30.9 0.0 3.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW72247.1 - 1.1e-14 53.0 1.0 0.00067 19.4 0.1 4.4 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RJW72247.1 - 1.6e-10 40.0 0.1 0.00032 20.1 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 RJW72247.1 - 2.9e-09 36.6 0.0 0.0046 16.8 0.0 3.2 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW72247.1 - 1.8e-06 28.3 0.0 0.0014 18.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SHOCT PF09851.9 RJW72247.1 - 0.0011 18.6 4.0 0.19 11.5 0.6 2.7 2 1 0 2 2 2 2 Short C-terminal domain EF-hand_10 PF14788.6 RJW72247.1 - 0.0035 17.2 0.9 0.21 11.4 0.0 3.2 2 1 1 3 3 3 1 EF hand EF-hand_13 PF17958.1 RJW72247.1 - 0.02 14.7 0.1 0.64 9.9 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 RJW72247.1 - 0.022 14.7 0.3 0.46 10.4 0.1 2.5 3 0 0 3 3 3 0 Caleosin related protein RST PF12174.8 RJW72247.1 - 0.032 14.2 0.4 0.88 9.5 0.1 2.5 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain LIM PF00412.22 RJW72250.1 - 4.9e-12 45.9 1.3 8.9e-12 45.1 1.3 1.5 1 0 0 1 1 1 1 LIM domain Sod_Cu PF00080.20 RJW72251.1 - 2e-10 41.0 0.0 3.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) GSHPx PF00255.19 RJW72252.1 - 8.4e-28 96.1 0.2 2.6e-25 88.1 0.0 2.1 1 1 1 2 2 2 2 Glutathione peroxidase Na_sulph_symp PF00939.19 RJW72254.1 - 1.6e-86 291.3 16.0 1.9e-86 291.0 16.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 RJW72254.1 - 1.5e-30 106.4 30.0 2.1e-19 69.9 0.8 2.9 2 2 1 3 3 3 3 Citrate transporter RVT_1 PF00078.27 RJW72255.1 - 2.8e-41 141.5 0.0 7.7e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW72255.1 - 5.7e-07 29.4 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase EF-hand_7 PF13499.6 RJW72256.1 - 2.5e-14 53.5 3.7 1.1e-09 38.6 1.2 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW72256.1 - 2.5e-13 48.5 0.4 1.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 RJW72256.1 - 1.3e-12 46.6 0.1 2.6e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW72256.1 - 6.6e-12 45.1 2.1 4e-08 33.0 0.7 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW72256.1 - 5.6e-11 41.5 0.3 0.00018 21.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RJW72256.1 - 0.00082 19.7 0.2 0.0011 19.2 0.2 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW72256.1 - 0.00097 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 RJW72256.1 - 0.0074 16.1 0.5 0.014 15.3 0.5 1.5 1 0 0 1 1 1 1 EF hand Lipocalin_8 PF16585.5 RJW72256.1 - 0.016 15.6 0.0 0.03 14.8 0.0 1.4 1 1 0 1 1 1 0 Lipocalin-like domain Toprim_2 PF13155.6 RJW72256.1 - 0.046 14.1 0.3 0.66 10.4 0.3 2.3 1 1 2 3 3 3 0 Toprim-like polyprenyl_synt PF00348.17 RJW72257.1 - 4.3e-57 193.1 0.0 6.1e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Rad10 PF03834.14 RJW72257.1 - 6.6e-47 158.2 0.3 1.2e-46 157.4 0.3 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 RJW72257.1 - 2.2e-06 28.2 0.0 4.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 RJW72257.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF5537 PF17690.1 RJW72258.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5537) RVT_1 PF00078.27 RJW72260.1 - 7.3e-45 153.2 0.0 1.1e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RJW72260.1 - 4.2e-07 29.7 1.0 1.4e-06 28.0 0.4 2.2 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RJW72260.1 - 5e-07 29.6 0.0 1.3e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TMEM65 PF10507.9 RJW72261.1 - 1e-28 99.4 3.1 5.2e-28 97.2 2.6 2.2 1 1 0 1 1 1 1 Transmembrane protein 65 EF-hand_1 PF00036.32 RJW72262.1 - 1.5e-07 30.4 2.2 0.012 15.1 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW72262.1 - 7.8e-07 28.5 0.9 0.012 15.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RJW72262.1 - 1.9e-06 28.2 0.5 3e-06 27.6 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RJW72262.1 - 0.00011 21.5 1.9 0.15 11.6 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW72262.1 - 0.00013 21.8 0.7 0.043 13.7 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_like PF09279.11 RJW72262.1 - 0.011 16.2 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like DUF2624 PF11116.8 RJW72262.1 - 0.044 14.7 0.0 0.1 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) ComX PF05952.12 RJW72262.1 - 0.14 12.2 0.1 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Bacillus competence pheromone ComX EF-hand_1 PF00036.32 RJW72264.1 - 1.6e-12 46.0 3.1 1.5e-06 27.3 0.3 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RJW72264.1 - 1.7e-10 40.0 0.9 1e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RJW72264.1 - 4.7e-10 39.8 1.3 5.1e-10 39.6 1.3 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RJW72264.1 - 7.7e-09 34.7 4.5 1.2e-08 34.0 0.3 2.3 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 RJW72264.1 - 1.9e-06 27.6 5.8 0.00013 21.7 1.5 2.0 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW72264.1 - 0.058 13.7 0.7 0.13 12.5 0.7 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.32 RJW72265.1 - 1.7e-21 74.1 4.6 1.4e-05 24.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW72265.1 - 6.7e-21 74.5 4.1 3.1e-10 40.3 1.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW72265.1 - 7.6e-17 59.7 3.2 1.6e-05 24.4 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RJW72265.1 - 8.2e-15 53.5 2.7 6.8e-05 22.2 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RJW72265.1 - 1.5e-13 50.4 4.2 0.00042 20.1 0.1 4.1 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW72265.1 - 2e-07 31.3 0.9 0.0032 17.8 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 RJW72265.1 - 0.0034 16.0 0.1 0.0034 16.0 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_4 PF12763.7 RJW72265.1 - 0.0083 16.1 2.8 4 7.4 0.0 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 RJW72265.1 - 0.022 14.6 0.4 0.12 12.3 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 RJW72265.1 - 0.099 13.0 0.4 12 6.3 0.1 3.2 2 1 2 4 4 4 0 EF-hand domain EF-hand_11 PF08976.11 RJW72265.1 - 0.13 13.1 0.5 1.3 9.9 0.0 2.5 2 1 1 3 3 3 0 EF-hand domain Caleosin PF05042.13 RJW72265.1 - 0.18 11.8 1.2 31 4.4 0.2 3.1 1 1 2 3 3 3 0 Caleosin related protein p25-alpha PF05517.12 RJW72265.1 - 0.22 11.7 3.2 0.5 10.5 1.4 2.1 1 1 1 2 2 2 0 p25-alpha ANF_receptor PF01094.28 RJW72267.1 - 4e-05 22.9 0.0 0.0072 15.5 0.0 2.8 1 1 0 2 2 2 2 Receptor family ligand binding region CPSase_sm_chain PF00988.22 RJW72267.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain DUF4604 PF15377.6 RJW72268.1 - 0.29 11.5 24.7 0.53 10.7 24.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) BUD22 PF09073.10 RJW72268.1 - 4.9 6.4 34.5 8.4 5.6 34.5 1.3 1 0 0 1 1 1 0 BUD22 Macro PF01661.21 RJW72269.1 - 1.5e-15 57.3 0.0 2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Macro domain MoeA_C PF03454.15 RJW72269.1 - 0.034 14.3 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) DUF4764 PF15961.5 RJW72269.1 - 0.24 10.1 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) EF-hand_7 PF13499.6 RJW72272.1 - 1.9e-32 111.5 3.6 1.9e-16 60.2 0.1 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW72272.1 - 4.2e-31 104.1 7.1 5.4e-08 31.8 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 RJW72272.1 - 1.7e-27 93.6 6.9 1e-07 31.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RJW72272.1 - 1.9e-26 89.7 6.8 1.8e-06 27.4 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RJW72272.1 - 5.6e-19 67.7 3.1 3.1e-09 36.6 0.2 3.7 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 RJW72272.1 - 2.2e-10 40.7 0.0 0.0001 22.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RJW72272.1 - 3.3e-08 33.8 0.9 3.8e-05 24.0 0.0 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 RJW72272.1 - 3.9e-07 30.2 6.3 0.083 12.8 0.1 4.0 1 1 3 4 4 4 2 Caleosin related protein EF-hand_10 PF14788.6 RJW72272.1 - 2.5e-05 24.1 6.4 0.16 11.8 0.1 3.7 3 1 1 4 4 4 2 EF hand DUF5580 PF17743.1 RJW72272.1 - 6.9e-05 21.6 0.2 6.9e-05 21.6 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Ish1 PF10281.9 RJW72272.1 - 0.0011 19.2 0.8 5.3 7.4 0.0 3.4 2 1 1 3 3 3 1 Putative stress-responsive nuclear envelope protein DUF1456 PF07308.13 RJW72272.1 - 0.0019 18.5 3.2 0.018 15.4 0.2 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF1456) EF-hand_11 PF08976.11 RJW72272.1 - 0.0085 17.0 0.3 1.5 9.7 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 RJW72272.1 - 0.012 15.6 1.1 2.3 8.2 0.1 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPF0240 PF06784.11 RJW72272.1 - 0.013 15.6 0.3 0.31 11.1 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0240) FRB_dom PF08771.11 RJW72272.1 - 0.015 15.7 1.5 0.082 13.3 0.1 2.2 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain PaaX PF07848.12 RJW72272.1 - 0.016 15.4 0.0 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 PaaX-like protein Dockerin_1 PF00404.18 RJW72272.1 - 0.019 15.1 0.0 4.2 7.6 0.0 3.1 4 0 0 4 4 4 0 Dockerin type I domain TFIIE_beta PF02186.15 RJW72272.1 - 0.04 14.2 2.6 1 9.7 0.3 2.7 2 1 0 3 3 3 0 TFIIE beta subunit core domain Excalibur PF05901.11 RJW72272.1 - 0.046 14.3 0.4 24 5.6 0.0 3.5 4 0 0 4 4 4 0 Excalibur calcium-binding domain HHH_4 PF14490.6 RJW72272.1 - 0.076 13.0 0.1 0.75 9.8 0.1 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix containing domain PMBR PF09373.10 RJW72272.1 - 0.087 13.0 0.2 21 5.5 0.0 3.6 4 0 0 4 4 4 0 Pseudomurein-binding repeat BCNT PF07572.12 RJW72272.1 - 0.12 12.5 4.1 5.9 7.1 0.1 2.7 2 2 0 2 2 2 0 Bucentaur or craniofacial development Slx4 PF09494.10 RJW72272.1 - 0.15 12.1 0.1 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 Slx4 endonuclease DUF3487 PF11990.8 RJW72272.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) RabGAP-TBC PF00566.18 RJW72273.1 - 3.1e-48 164.3 0.0 4.6e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.19 RJW72273.1 - 2.1e-30 105.4 0.1 5.6e-30 104.0 0.1 1.7 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.28 RJW72273.1 - 4.8e-12 45.3 0.1 9.1e-12 44.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RJW72273.1 - 2.9e-11 42.9 0.0 7.6e-11 41.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 RJW72273.1 - 4.4e-11 42.4 0.0 9e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ComZ PF10815.8 RJW72273.1 - 0.0017 18.3 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 ComZ RRM_1 PF00076.22 RJW72274.1 - 1.4e-17 63.3 0.1 2.6e-17 62.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.27 RJW72274.1 - 7.1e-09 35.5 0.0 2.3e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 RJW72274.1 - 0.0004 20.6 0.2 0.0018 18.5 0.1 2.0 2 0 0 2 2 2 1 GIY-YIG catalytic domain RRM_5 PF13893.6 RJW72274.1 - 0.085 12.4 0.0 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HD_4 PF13328.6 RJW72274.1 - 3 7.6 9.0 0.61 9.8 0.7 3.6 5 0 0 5 5 5 0 HD domain G-alpha PF00503.20 RJW72276.1 - 2.5e-96 323.0 0.2 3.1e-96 322.6 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RJW72276.1 - 6.4e-13 48.5 0.2 2.5e-12 46.6 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW72276.1 - 0.004 16.6 0.1 0.0078 15.6 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 RJW72276.1 - 0.072 13.3 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase EptA_B_N PF08019.12 RJW72279.1 - 0.0059 16.5 1.8 0.067 13.1 0.6 2.1 2 0 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB DUF2231 PF09990.9 RJW72279.1 - 0.045 14.2 0.4 0.82 10.1 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF4212 PF13937.6 RJW72279.1 - 0.051 14.0 0.9 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Claudin_2 PF13903.6 RJW72279.1 - 0.095 12.4 10.9 0.13 12.0 0.9 2.8 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 RJW72279.1 - 0.14 11.8 10.6 0.13 11.9 2.0 2.8 2 1 1 3 3 3 0 SUR7/PalI family DUF2768 PF10966.8 RJW72279.1 - 0.24 11.8 5.7 4 8.0 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2768) MARVEL PF01284.23 RJW72279.1 - 0.41 10.7 12.2 46 4.0 14.2 2.5 1 1 1 2 2 2 0 Membrane-associating domain EF-hand_1 PF00036.32 RJW72280.1 - 5.6e-13 47.4 2.3 1.8e-06 27.1 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RJW72280.1 - 1.1e-11 45.0 2.7 1.3e-11 44.8 2.7 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW72280.1 - 5.3e-11 41.5 2.0 7.9e-05 22.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RJW72280.1 - 1.2e-08 34.0 3.1 0.00023 20.5 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RJW72280.1 - 1.2e-05 25.1 2.7 0.00012 21.8 1.5 2.0 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW72280.1 - 0.00056 20.2 1.2 0.00089 19.6 1.2 1.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW72280.1 - 0.00072 19.5 0.6 0.00084 19.3 0.6 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.11 RJW72280.1 - 0.067 13.7 0.4 0.081 13.4 0.4 1.2 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Ribosomal_S18 PF01084.20 RJW72282.1 - 0.013 15.7 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S18 DUF1907 PF08925.11 RJW72283.1 - 2.2e-78 263.6 0.0 3e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) Pkinase PF00069.25 RJW72287.1 - 4.3e-36 124.6 0.0 1.5e-35 122.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72287.1 - 3e-13 49.6 0.0 4.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 RJW72287.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 RJW72287.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MIP PF00230.20 RJW72288.1 - 2e-45 155.3 7.5 2.4e-45 155.0 7.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2583 PF10762.9 RJW72288.1 - 0.12 12.9 1.2 1.1 9.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) UL16 PF17622.2 RJW72289.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Viral unique long protein 16 Ras PF00071.22 RJW72290.1 - 2.2e-54 183.4 0.0 2.5e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW72290.1 - 2.1e-23 82.8 0.0 2.8e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW72290.1 - 7.1e-09 35.4 0.0 8.3e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family 14-3-3 PF00244.20 RJW72293.1 - 8.2e-85 283.8 8.2 1e-84 283.5 8.2 1.1 1 0 0 1 1 1 1 14-3-3 protein Nro1 PF12753.7 RJW72293.1 - 0.034 13.1 4.5 0.65 8.9 1.2 2.4 1 1 1 2 2 2 0 Nuclear pore complex subunit Nro1 DUF4168 PF13767.6 RJW72293.1 - 0.035 15.3 0.9 1.5 10.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) EF-hand_7 PF13499.6 RJW72297.1 - 8.8e-11 42.1 2.8 6.7e-10 39.3 1.6 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW72297.1 - 1.8e-08 33.3 2.9 0.0018 17.7 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RJW72297.1 - 2.9e-08 33.0 4.9 0.0017 18.1 0.1 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RJW72297.1 - 5.2e-08 32.0 2.8 0.017 14.6 0.7 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RJW72297.1 - 4e-05 23.4 6.5 0.0027 17.5 1.0 3.1 3 1 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW72297.1 - 0.024 15.0 0.1 0.61 10.4 0.1 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Neur_chan_LBD PF02931.23 RJW72300.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF4448 PF14610.6 RJW72301.1 - 0.006 16.4 0.1 0.0078 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 RJW72301.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Cadherin_C_2 PF16492.5 RJW72301.1 - 0.013 16.2 0.0 0.028 15.1 0.0 1.6 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Hum_adeno_E3A PF05393.11 RJW72301.1 - 0.062 13.3 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Col_cuticle_N PF01484.17 RJW72301.1 - 1.9 8.6 7.2 2.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain TMIE PF16038.5 RJW72301.1 - 7.1 6.5 8.4 0.77 9.6 3.1 1.8 2 0 0 2 2 2 0 TMIE protein Ras PF00071.22 RJW72302.1 - 1.2e-39 135.5 0.0 1.3e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW72302.1 - 1.1e-20 74.1 0.0 1.4e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW72302.1 - 3.3e-11 42.9 0.0 3.8e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family zf-CW PF07496.15 RJW72303.1 - 0.018 15.1 0.5 0.38 10.8 0.2 2.4 2 0 0 2 2 2 0 CW-type Zinc Finger Neur_chan_memb PF02932.16 RJW72304.1 - 3.9e-42 145.0 4.5 1.7e-40 139.6 4.5 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region ubiquitin PF00240.23 RJW72308.1 - 2.1e-11 43.4 0.0 3.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 RJW72308.1 - 6.8e-07 29.1 31.1 0.0056 16.6 4.3 5.9 4 2 1 5 5 5 3 STI1 domain UBA PF00627.31 RJW72308.1 - 1e-06 28.5 0.6 5.6e-06 26.1 0.6 2.5 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 RJW72308.1 - 0.0018 18.4 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 RJW72308.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 RJW72308.1 - 0.14 12.7 0.0 0.42 11.2 0.0 1.8 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain BtpA PF03437.15 RJW72308.1 - 0.17 11.3 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 BtpA family BSD PF03909.17 RJW72308.1 - 0.46 10.5 5.3 4 7.5 0.2 3.6 2 1 1 3 3 3 0 BSD domain RPN13_C PF16550.5 RJW72308.1 - 0.59 10.3 10.1 0.25 11.5 2.4 3.3 3 1 0 3 3 3 0 UCH-binding domain CRF PF00473.17 RJW72308.1 - 1.6 8.8 8.0 1.5 8.9 0.4 3.2 3 1 0 3 3 3 0 Corticotropin-releasing factor family Y_phosphatase PF00102.27 RJW72313.1 - 2.3e-62 210.7 0.1 4.1e-31 108.4 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 RJW72313.1 - 1.5e-19 70.3 0.0 2.4e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RJW72313.1 - 7e-09 36.0 0.1 1.4e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DSPc PF00782.20 RJW72313.1 - 0.0071 16.2 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RJW72313.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1308 PF07000.11 RJW72315.1 - 5.5e-27 94.7 0.0 3e-23 82.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1308) DUF5614 PF18474.1 RJW72315.1 - 0.014 14.8 0.0 0.11 11.8 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5614) Mesd PF10185.9 RJW72315.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor Tecti-min-caps PF09300.10 RJW72315.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Tectiviridae, minor capsid Ribophorin_II PF05817.14 RJW72316.1 - 8.3e-07 27.9 0.1 9e-07 27.8 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4724 PF15852.5 RJW72317.1 - 2.9 8.4 5.8 0.77 10.3 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4724) ANAPC4_WD40 PF12894.7 RJW72318.1 - 5.6e-05 23.4 0.1 6.2 7.2 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RJW72318.1 - 0.021 14.2 0.0 3.7 6.8 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain T2SS-T3SS_pil_N PF13629.6 RJW72318.1 - 0.073 12.8 0.4 1.7 8.4 0.2 2.8 2 0 0 2 2 2 0 Pilus formation protein N terminal region MIP PF00230.20 RJW72319.1 - 6.3e-35 120.9 12.0 7.5e-35 120.7 12.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Histone PF00125.24 RJW72320.1 - 2e-21 76.7 2.4 2.6e-21 76.3 2.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FCH PF00611.23 RJW72324.1 - 1.2e-06 28.7 0.5 4.8e-06 26.8 0.5 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain HR1 PF02185.16 RJW72324.1 - 0.041 14.0 0.4 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Hr1 repeat SHE3 PF17078.5 RJW72324.1 - 0.067 12.9 0.2 1.6 8.4 0.0 2.9 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 REC1 PF18501.1 RJW72324.1 - 0.091 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Alpha helical recognition lobe domain QVR PF17064.5 RJW72326.1 - 9.1e-06 25.8 9.4 1.2e-05 25.4 9.4 1.2 1 0 0 1 1 1 1 Sleepless protein C1_1 PF00130.22 RJW72326.1 - 0.042 13.7 0.4 0.042 13.7 0.4 2.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UPAR_LY6 PF00021.21 RJW72326.1 - 0.9 10.3 12.4 1.6 9.5 12.4 1.4 1 1 0 1 1 1 0 u-PAR/Ly-6 domain GLTP PF08718.11 RJW72328.1 - 2e-32 112.5 0.0 5.9e-32 111.0 0.0 1.8 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PH PF00169.29 RJW72328.1 - 2.3e-12 47.4 0.1 4.4e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RJW72328.1 - 2e-05 24.9 0.3 9e-05 22.8 0.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RJW72328.1 - 4.3e-05 23.7 0.0 7.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain 7TM_GPCR_Srw PF10324.9 RJW72329.1 - 4e-05 23.1 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RJW72329.1 - 5.1e-05 22.7 0.1 6.2e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srb PF02175.16 RJW72329.1 - 0.063 13.0 0.3 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb F-box-like PF12937.7 RJW72330.1 - 3e-09 36.6 4.0 4.8e-09 36.0 4.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RJW72330.1 - 6e-07 29.2 0.9 1.1e-06 28.4 0.9 1.4 1 0 0 1 1 1 1 F-box domain 7tm_1 PF00001.21 RJW72333.1 - 0.00076 18.9 3.4 0.0014 18.0 2.7 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW72333.1 - 0.01 15.2 3.6 0.016 14.5 3.6 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw DNA_Packaging_2 PF11123.8 RJW72333.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 DNA packaging protein Peptidase_M14 PF00246.24 RJW72334.1 - 2.1e-13 50.7 0.3 1.1e-12 48.4 0.0 2.3 2 1 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.14 RJW72334.1 - 0.0011 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Ig_3 PF13927.6 RJW72335.1 - 5.1e-07 30.2 0.1 0.00011 22.8 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RJW72335.1 - 0.00046 20.2 0.0 0.01 15.9 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain CcmD PF04995.14 RJW72335.1 - 0.0021 18.1 0.1 0.0041 17.2 0.1 1.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) MG2 PF01835.19 RJW72335.1 - 0.058 13.8 0.0 0.56 10.7 0.0 2.3 2 0 0 2 2 2 0 MG2 domain Granulin PF00396.18 RJW72336.1 - 1.8e-73 242.6 226.8 2.7e-16 59.6 21.0 12.6 12 1 1 13 13 13 8 Granulin Lipocalin_8 PF16585.5 RJW72337.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipocalin-like domain Pkinase_Tyr PF07714.17 RJW72338.1 - 3.1e-62 210.2 0.0 4.5e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW72338.1 - 2.2e-59 201.0 0.0 3.3e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RJW72338.1 - 0.0064 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like GPHR_N PF12537.8 RJW72340.1 - 0.015 15.4 0.1 0.045 13.8 0.0 1.7 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Ada_Zn_binding PF02805.16 RJW72341.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Metal binding domain of Ada ChaB PF06150.12 RJW72341.1 - 0.2 12.3 2.0 4.7 7.9 0.1 2.9 2 1 0 3 3 3 0 ChaB RVT_1 PF00078.27 RJW72342.1 - 7e-24 84.6 0.0 9.9e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FERM_C PF09380.10 RJW72344.1 - 1.5e-14 54.2 0.4 3.1e-14 53.1 0.4 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RJW72344.1 - 1.4e-12 48.1 0.0 4.8e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 FERM central domain CreA PF05981.12 RJW72345.1 - 0.17 11.9 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 CreA protein RBP_receptor PF14752.6 RJW72349.1 - 8.1e-47 160.1 30.8 6.3e-46 157.2 30.8 2.0 1 1 0 1 1 1 1 Retinol binding protein receptor DUF2511 PF10709.9 RJW72350.1 - 0.05 13.9 0.0 0.057 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2511) RVT_1 PF00078.27 RJW72351.1 - 2.4e-19 69.7 0.0 4.3e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Neur_chan_LBD PF02931.23 RJW72352.1 - 7.4e-37 126.9 3.1 1.1e-36 126.3 2.8 1.4 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Pepdidase_M14_N PF18027.1 RJW72357.1 - 6.1e-14 52.3 0.2 1.7e-13 50.8 0.2 1.8 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain DNA_ligase_A_C PF04679.15 RJW72357.1 - 0.043 14.4 0.3 0.45 11.1 0.3 2.6 1 1 0 1 1 1 0 ATP dependent DNA ligase C terminal region LURAP PF14854.6 RJW72358.1 - 0.17 11.8 0.0 0.91 9.5 0.0 2.0 2 0 0 2 2 2 0 Leucine rich adaptor protein Ig_3 PF13927.6 RJW72359.1 - 5e-23 81.5 0.4 1.9e-06 28.3 0.0 6.3 5 1 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 RJW72359.1 - 2.2e-18 66.1 0.0 1.6e-09 37.7 0.0 5.7 6 0 0 6 6 6 3 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW72359.1 - 1.2e-12 47.9 0.1 0.005 17.2 0.0 5.9 6 0 0 6 6 6 3 Immunoglobulin domain ig PF00047.25 RJW72359.1 - 1.1e-08 35.1 0.1 2.6 8.3 0.0 6.2 6 1 0 6 6 6 3 Immunoglobulin domain C2-set_2 PF08205.12 RJW72359.1 - 3.3e-06 27.1 9.3 0.0011 19.0 0.0 5.2 5 1 0 5 5 5 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RJW72359.1 - 0.00012 22.2 1.2 2.3 8.5 0.0 5.7 6 1 0 6 6 6 1 Immunoglobulin V-set domain zf-CW PF07496.15 RJW72360.1 - 0.03 14.4 2.8 0.047 13.7 0.9 2.0 2 0 0 2 2 2 0 CW-type Zinc Finger Ribophorin_II PF05817.14 RJW72362.1 - 3.4e-114 382.7 0.0 4.6e-114 382.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Ofd1_CTDD PF10637.9 RJW72362.1 - 0.21 10.9 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term A2L_zn_ribbon PF08792.10 RJW72363.1 - 0.099 12.4 1.0 0.099 12.4 1.0 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain Pilus_CpaD PF09476.10 RJW72363.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) 7tm_1 PF00001.21 RJW72364.1 - 2.4e-05 23.8 9.0 2.4e-05 23.8 9.0 1.8 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW72364.1 - 0.00069 19.0 11.5 0.0015 17.9 11.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 RJW72364.1 - 0.0018 17.7 1.6 0.0018 17.7 1.6 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF5042 PF16445.5 RJW72364.1 - 0.087 11.2 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) 7tm_1 PF00001.21 RJW72366.1 - 0.00013 21.4 1.4 0.00015 21.2 1.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW72366.1 - 0.0041 16.5 0.3 0.0058 16.0 0.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx BetaGal_dom4_5 PF13364.6 RJW72366.1 - 0.066 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain DUF445 PF04286.12 RJW72367.1 - 1.8e-08 34.6 61.1 2.5e-06 27.6 61.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF445) GerPC PF10737.9 RJW72367.1 - 3.2e-06 27.3 64.2 0.018 15.1 19.4 3.3 1 1 2 3 3 3 3 Spore germination protein GerPC SecD_SecF PF02355.16 RJW72367.1 - 2.1e-05 24.0 54.3 1.8e+04 -39.9 54.3 8.7 1 1 0 1 1 1 0 Protein export membrane protein EcsC PF12787.7 RJW72367.1 - 0.001 18.8 35.2 1.8e+04 -19.3 35.2 5.8 1 1 0 1 1 1 0 EcsC protein family RHD3 PF05879.12 RJW72367.1 - 0.013 13.7 41.6 0.26 9.4 19.3 2.1 1 1 1 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) Hyd_WA PF06462.12 RJW72367.1 - 0.11 12.5 0.1 16 5.6 0.0 3.1 3 0 0 3 3 3 0 Propeller DUF4923 PF16270.5 RJW72368.1 - 0.0042 16.9 0.1 2.2 8.1 0.0 2.1 2 0 0 2 2 2 2 Lipocalin-like domain (DUF4923) LpxC PF03331.13 RJW72368.1 - 0.0075 15.8 0.0 3.8 6.9 0.0 2.1 2 0 0 2 2 2 2 UDP-3-O-acyl N-acetylglycosamine deacetylase DUF2205 PF10224.9 RJW72368.1 - 0.012 15.6 0.0 7.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Short coiled-coil protein Alpha-amyl_C PF09071.10 RJW72368.1 - 0.025 14.4 0.1 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Alpha-amylase, C terminal DUF1577 PF07614.11 RJW72369.1 - 0.064 12.3 0.1 0.12 11.4 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1577) MIP PF00230.20 RJW72370.1 - 6.6e-32 111.0 15.7 7.9e-32 110.8 15.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein APP_N PF02177.16 RJW72371.1 - 0.0016 18.7 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding DUF1451 PF07295.11 RJW72371.1 - 0.085 12.9 1.7 0.2 11.7 1.5 1.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain PAW PF04721.17 RJW72372.1 - 2.7e-35 122.0 0.0 3.6e-34 118.3 0.0 2.1 1 1 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Transglut_core PF01841.19 RJW72372.1 - 0.00013 22.4 0.6 0.002 18.6 0.6 2.9 3 1 0 3 3 3 1 Transglutaminase-like superfamily Rad4 PF03835.15 RJW72372.1 - 0.05 13.3 0.1 7.9 6.1 0.1 2.3 2 0 0 2 2 2 0 Rad4 transglutaminase-like domain PHZA_PHZB PF03284.13 RJW72372.1 - 0.11 12.1 0.6 0.24 11.0 0.6 1.4 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B MIP PF00230.20 RJW72373.1 - 1.3e-46 159.1 6.1 1.6e-46 158.9 6.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1269 PF06897.12 RJW72373.1 - 0.041 14.2 0.3 0.88 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) HTH_AraC PF00165.23 RJW72374.1 - 0.045 13.9 0.3 0.095 12.8 0.3 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Str_synth PF03088.16 RJW72374.1 - 0.08 13.1 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Strictosidine synthase Peptidase_S49 PF01343.18 RJW72377.1 - 0.028 14.4 0.2 0.041 13.8 0.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 F-box-like PF12937.7 RJW72378.1 - 4.1e-05 23.4 2.5 9.3e-05 22.2 2.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RJW72378.1 - 0.00069 19.4 0.6 0.0016 18.3 0.6 1.6 1 0 0 1 1 1 1 F-box domain DUF4508 PF14969.6 RJW72378.1 - 0.002 18.4 0.1 0.004 17.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) DHHC PF01529.20 RJW72379.1 - 1e-25 90.4 11.3 1e-25 90.4 11.3 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Glyco_transf_7C PF02709.14 RJW72381.1 - 4.1e-22 77.6 0.2 8.9e-22 76.5 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 RJW72381.1 - 5.8e-20 71.3 0.1 1.3e-18 67.0 0.1 2.4 1 1 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Nore1-SARAH PF16517.5 RJW72381.1 - 1.1e-11 44.4 0.2 2e-11 43.6 0.2 1.4 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RA PF00788.23 RJW72381.1 - 9.3e-11 42.2 0.1 2.9e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Glyco_tranf_2_2 PF10111.9 RJW72381.1 - 0.00069 19.2 0.3 0.0018 17.8 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 LIN37 PF15306.6 RJW72382.1 - 4.3e-34 118.0 0.0 8.1e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 LIN37 zf-CCCH PF00642.24 RJW72383.1 - 4.8e-15 55.0 4.3 2.2e-08 33.8 0.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RJW72383.1 - 7e-06 25.9 5.3 0.0013 18.7 0.5 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 RJW72383.1 - 0.18 12.5 5.6 5.6 7.7 0.6 2.2 1 1 1 2 2 2 0 Torus domain Bcl-2 PF00452.19 RJW72385.1 - 1.7e-14 54.3 0.1 2.4e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family c-SKI_SMAD_bind PF08782.10 RJW72385.1 - 0.00041 20.5 0.0 0.0011 19.2 0.0 1.7 1 1 0 1 1 1 1 c-SKI Smad4 binding domain Atg14 PF10186.9 RJW72387.1 - 0.002 17.2 0.6 0.0027 16.8 0.6 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin_2 PF14523.6 RJW72387.1 - 0.0045 17.3 4.6 0.0083 16.5 0.4 2.6 1 1 1 2 2 2 1 Syntaxin-like protein pP_pnuc_1 PF18165.1 RJW72387.1 - 0.011 15.6 0.3 0.036 13.9 0.0 1.9 2 1 1 3 3 3 0 Predicted pPIWI-associating nuclease Syntaxin PF00804.25 RJW72387.1 - 0.015 15.0 1.4 0.015 15.0 1.4 2.3 2 1 0 2 2 2 0 Syntaxin GAS PF13851.6 RJW72387.1 - 0.027 13.8 1.0 0.35 10.2 0.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Dynactin_p22 PF07426.11 RJW72387.1 - 0.099 12.5 2.7 0.59 10.0 0.0 2.4 3 0 0 3 3 3 0 Dynactin subunit p22 ArAE_2_N PF10337.9 RJW72387.1 - 0.1 11.6 0.3 0.13 11.3 0.3 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 RJW72387.1 - 0.11 11.0 1.6 0.12 10.8 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Occludin_ELL PF07303.13 RJW72387.1 - 0.16 12.7 1.8 0.6 10.9 0.1 2.4 2 1 1 3 3 3 0 Occludin homology domain LXG PF04740.12 RJW72387.1 - 0.53 10.0 5.2 1.6 8.4 2.4 2.2 1 1 0 2 2 2 0 LXG domain of WXG superfamily DivIC PF04977.15 RJW72387.1 - 0.75 9.6 4.6 9.2 6.1 1.3 3.0 3 0 0 3 3 3 0 Septum formation initiator HMG_box PF00505.19 RJW72388.1 - 2e-19 69.7 1.3 4.5e-19 68.6 1.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RJW72388.1 - 4.2e-08 33.7 0.8 1.4e-07 32.0 0.8 1.8 1 0 0 1 1 1 1 HMG-box domain RVT_1 PF00078.27 RJW72388.1 - 0.00075 19.1 0.0 0.087 12.3 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) CTNNB1_binding PF08347.11 RJW72388.1 - 0.78 9.9 4.5 0.19 11.9 0.4 2.0 2 0 0 2 2 2 0 N-terminal CTNNB1 binding Na_H_Exchanger PF00999.21 RJW72389.1 - 2.7e-58 197.6 49.5 3.4e-58 197.2 49.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 RJW72390.1 - 2.7e-57 194.3 39.9 3.5e-57 193.9 39.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SLS PF14611.6 RJW72390.1 - 0.024 14.5 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator BrkDBD PF09607.10 RJW72390.1 - 0.15 11.8 0.3 0.34 10.7 0.3 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain Filamin PF00630.19 RJW72392.1 - 2e-06 28.5 0.0 2.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat TPR_MLP1_2 PF07926.12 RJW72392.1 - 0.0023 18.0 2.2 0.0025 17.8 0.3 1.9 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.6 RJW72392.1 - 0.004 17.5 0.9 0.039 14.3 0.4 2.6 2 1 1 3 3 3 1 Syntaxin-like protein Syntaxin-6_N PF09177.11 RJW72392.1 - 0.0053 17.3 2.2 0.26 11.8 0.7 2.6 1 1 1 2 2 2 1 Syntaxin 6, N-terminal CdvA PF18822.1 RJW72392.1 - 0.14 12.0 1.4 0.7 9.7 0.2 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF3584 PF12128.8 RJW72392.1 - 0.21 9.0 2.5 0.29 8.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 RJW72392.1 - 0.23 11.7 1.8 3 8.0 1.2 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family P4Ha_N PF08336.11 RJW72392.1 - 0.27 11.2 2.8 0.15 12.1 0.6 1.8 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TMPIT PF07851.13 RJW72392.1 - 0.28 10.4 0.8 0.45 9.7 0.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein Jnk-SapK_ap_N PF09744.9 RJW72392.1 - 0.32 11.2 3.5 1.3 9.3 3.3 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CorA PF01544.18 RJW72392.1 - 0.42 9.9 4.2 0.76 9.0 4.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prefoldin PF02996.17 RJW72392.1 - 0.69 9.8 3.7 0.9 9.5 0.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit Na_H_Exchanger PF00999.21 RJW72393.1 - 1.8e-55 188.3 48.0 2.4e-55 187.9 48.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Sec23_trunk PF04811.15 RJW72395.1 - 8.1e-65 218.8 0.0 1.1e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 RJW72395.1 - 1.3e-18 66.6 0.0 2.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RJW72395.1 - 1.3e-16 61.1 0.0 2.5e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 RJW72395.1 - 6.8e-15 54.8 0.7 1.5e-14 53.8 0.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 RJW72395.1 - 2.7e-11 43.2 0.0 3.1e-10 39.8 0.0 2.4 2 0 0 2 2 2 1 Gelsolin repeat Na_H_Exchanger PF00999.21 RJW72396.1 - 1e-54 185.8 49.0 1.3e-54 185.5 49.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Amidase PF01425.21 RJW72397.1 - 2.4e-90 303.7 0.0 5.6e-87 292.6 0.0 2.0 1 1 0 1 1 1 1 Amidase Adaptin_N PF01602.20 RJW72399.1 - 2.4e-95 320.1 3.8 5.9e-95 318.8 3.8 1.5 1 1 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 RJW72399.1 - 1.2e-54 184.1 0.0 2.2e-54 183.2 0.0 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 RJW72399.1 - 2.1e-15 56.8 1.2 9.3e-15 54.7 0.2 2.5 3 0 0 3 3 3 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 RJW72399.1 - 1.4e-10 41.4 10.7 3.2e-07 30.5 0.1 4.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RJW72399.1 - 2e-08 34.5 0.7 0.02 15.3 0.0 4.7 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.22 RJW72399.1 - 2.5e-08 33.5 0.0 0.013 15.7 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 RJW72399.1 - 0.0012 19.3 0.4 3.9 8.1 0.0 3.4 3 0 0 3 3 3 2 HEAT-like repeat PaaB PF06243.11 RJW72399.1 - 0.16 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Phenylacetic acid degradation B Period_C PF12114.8 RJW72399.1 - 0.6 9.7 3.1 1.2 8.6 3.1 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SH2 PF00017.24 RJW72400.1 - 2.5e-11 43.5 0.0 5.1e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.19 RJW72400.1 - 3.4e-06 27.4 0.0 6.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RVT_1 PF00078.27 RJW72401.1 - 9.3e-17 61.3 0.0 6.7e-11 42.1 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 RJW72401.1 - 8.3 4.6 22.1 4.6 5.4 19.6 1.7 2 0 0 2 2 2 0 CDC45-like protein PP2C PF00481.21 RJW72402.1 - 4.8e-23 82.1 0.0 2.2e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 RJW72402.1 - 0.00035 20.3 0.0 0.0013 18.4 0.0 1.9 2 1 0 2 2 2 1 Protein phosphatase 2C Amidase PF01425.21 RJW72403.1 - 1.1e-61 209.2 0.0 1.6e-61 208.7 0.0 1.2 1 0 0 1 1 1 1 Amidase GST_N_3 PF13417.6 RJW72405.1 - 9e-17 61.3 0.0 2.1e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RJW72405.1 - 6.9e-14 51.9 0.0 1.8e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RJW72405.1 - 4.9e-10 39.6 0.0 9.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RJW72405.1 - 1.9e-07 31.2 0.0 6.4e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RJW72405.1 - 8.7e-07 29.1 0.0 1.9e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RJW72405.1 - 4e-06 26.8 0.0 1.5e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 RJW72405.1 - 0.0012 19.0 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 RJW72405.1 - 0.0089 16.8 0.0 0.023 15.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RJW72405.1 - 0.03 14.1 0.2 0.09 12.6 0.2 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TRAUB PF08164.12 RJW72407.1 - 1.4e-10 41.6 0.0 1.6e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal DUF1487 PF07368.11 RJW72408.1 - 0.027 13.9 0.1 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Eapp_C PF10238.9 RJW72411.1 - 1.1e-23 84.0 0.0 2.5e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 E2F-associated phosphoprotein Fucose_iso_N2 PF07882.12 RJW72411.1 - 0.056 13.0 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain HTH_AraC PF00165.23 RJW72412.1 - 0.16 12.1 0.3 0.16 12.1 0.3 2.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family TMEM51 PF15345.6 RJW72413.1 - 0.0018 18.2 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 SPC12 PF06645.13 RJW72413.1 - 0.0019 18.3 2.0 0.076 13.1 0.1 2.6 2 0 0 2 2 2 1 Microsomal signal peptidase 12 kDa subunit (SPC12) SKG6 PF08693.10 RJW72413.1 - 2.6 7.5 8.5 6.2 6.3 8.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 RJW72413.1 - 3.4 7.5 7.6 0.19 11.5 0.2 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 ApeC PF16977.5 RJW72416.1 - 4.8e-66 222.6 8.4 3e-25 89.4 0.0 8.4 3 2 5 8 8 8 6 C-terminal domain of apextrin EGF_3 PF12947.7 RJW72416.1 - 0.0032 17.6 4.8 0.0032 17.6 4.8 4.0 3 0 0 3 3 3 2 EGF domain cEGF PF12662.7 RJW72416.1 - 0.16 11.9 32.1 0.33 10.9 2.8 6.6 6 0 0 6 6 6 0 Complement Clr-like EGF-like Amidase PF01425.21 RJW72417.1 - 7.3e-103 344.9 0.0 8.4e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Amidase BH4 PF02180.17 RJW72417.1 - 0.23 11.3 0.3 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Bcl-2 homology region 4 Ribosomal_L29 PF00831.23 RJW72417.1 - 5.2 7.1 6.8 3.4 7.7 2.5 2.7 1 1 0 2 2 2 0 Ribosomal L29 protein GWT1 PF06423.12 RJW72419.1 - 4.6e-14 52.8 10.5 4.6e-14 52.8 10.5 3.4 3 2 0 3 3 3 1 GWT1 Acid_PPase PF12689.7 RJW72422.1 - 2.3e-43 147.9 0.1 3.8e-43 147.3 0.1 1.3 1 1 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 RJW72422.1 - 0.00059 20.0 0.1 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Na_H_Exchanger PF00999.21 RJW72424.1 - 1.2e-58 198.7 44.0 1.6e-58 198.4 44.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HTH_AraC PF00165.23 RJW72427.1 - 0.079 13.1 0.5 0.31 11.2 0.7 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Na_H_Exchanger PF00999.21 RJW72430.1 - 1.7e-57 194.9 47.5 2.3e-57 194.6 47.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SPT16 PF08644.11 RJW72431.1 - 1.7e-54 184.1 0.1 1.7e-54 184.1 0.1 2.5 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 RJW72431.1 - 1.1e-36 126.0 0.0 2.5e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 RJW72431.1 - 1.3e-19 70.7 0.0 2.8e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 RJW72431.1 - 2.1e-13 50.5 0.3 1.1e-12 48.2 0.0 2.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF3782 PF12644.7 RJW72431.1 - 0.11 12.7 0.1 1.5 9.0 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) DDE_1 PF03184.19 RJW72432.1 - 6.3e-35 120.4 0.0 1.7e-34 119.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RJW72432.1 - 4.3e-16 58.7 0.0 1.1e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 RJW72432.1 - 4.1e-08 32.7 0.5 8.3e-08 31.7 0.5 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 RJW72432.1 - 0.00013 21.7 0.7 0.00035 20.3 0.5 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RJW72432.1 - 0.0095 15.7 0.5 0.029 14.2 0.5 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 RJW72432.1 - 0.0096 16.0 0.1 0.023 14.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 RJW72432.1 - 0.05 13.7 0.1 0.17 12.0 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Exo84_C PF16528.5 RJW72434.1 - 6.1e-12 45.8 4.8 1.7e-10 41.1 0.7 3.8 3 1 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 RJW72434.1 - 1.3e-06 28.4 0.9 5.4e-06 26.4 0.5 2.3 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 RJW72434.1 - 0.00027 21.0 0.5 0.0017 18.4 0.5 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_C97 PF05903.14 RJW72436.1 - 2.8e-11 43.5 0.0 5.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain AA_permease_2 PF13520.6 RJW72438.1 - 5.9e-47 160.5 34.8 5.9e-47 160.5 34.8 2.5 2 1 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 RJW72438.1 - 4.4e-30 104.7 31.5 4.4e-30 104.7 31.5 2.6 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RJW72438.1 - 1.3e-21 76.4 10.8 1.3e-21 76.4 10.8 3.6 3 0 0 3 3 3 1 C-terminus of AA_permease Patatin PF01734.22 RJW72439.1 - 4.1e-12 46.7 0.0 1e-11 45.4 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Acyl-thio_N PF12590.8 RJW72440.1 - 4 8.0 6.4 0.86 10.2 0.7 2.7 3 0 0 3 3 3 0 Acyl-ATP thioesterase CO_deh_flav_C PF03450.17 RJW72441.1 - 0.11 12.7 0.2 20 5.4 0.0 2.2 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Reprolysin_5 PF13688.6 RJW72443.1 - 0.098 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 QVR PF17064.5 RJW72444.1 - 0.06 13.6 3.8 0.24 11.7 3.8 1.9 1 1 0 1 1 1 0 Sleepless protein Activin_recp PF01064.23 RJW72444.1 - 0.13 13.4 3.1 0.53 11.4 3.0 2.0 1 1 0 1 1 1 0 Activin types I and II receptor domain Sacchrp_dh_C PF16653.5 RJW72445.1 - 1.2e-79 268.1 0.0 3.8e-79 266.5 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 RJW72445.1 - 6.1e-27 94.6 0.0 1.4e-26 93.4 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 RJW72445.1 - 8.5e-15 55.2 0.0 2e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 RJW72445.1 - 3.8e-07 29.6 0.0 0.00024 20.5 0.0 3.0 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 RJW72445.1 - 0.00049 20.2 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TTL PF03133.15 RJW72446.1 - 5.7e-81 271.9 0.1 1.6e-80 270.4 0.0 1.8 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RJW72446.1 - 7.9e-06 25.3 0.0 0.0072 15.6 0.0 2.9 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RJW72446.1 - 0.0049 16.2 0.0 1.4 8.1 0.0 2.6 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp Dynamin_M PF01031.20 RJW72448.1 - 2.2e-100 335.5 0.0 4.5e-100 334.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 RJW72448.1 - 3.2e-54 183.5 0.0 8e-54 182.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 RJW72448.1 - 4.3e-32 110.1 1.5 8.9e-32 109.1 1.5 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 RJW72448.1 - 0.00087 19.4 0.0 0.0047 17.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 RJW72448.1 - 0.055 12.8 0.2 2.3 7.5 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Baculo_PEP_C PF04513.12 RJW72448.1 - 0.082 12.9 1.2 3 7.9 0.4 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_16 PF13191.6 RJW72448.1 - 0.091 13.1 0.0 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_C2 PF00648.21 RJW72449.1 - 7.8e-47 159.7 0.0 1.2e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease RVT_1 PF00078.27 RJW72449.1 - 7e-33 114.0 0.0 2.6e-32 112.1 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Calpain_III PF01067.22 RJW72449.1 - 3.5e-17 63.0 0.0 8.4e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 RJW72449.1 - 3.9e-11 43.2 0.0 8.3e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain Exo_endo_phos_2 PF14529.6 RJW72449.1 - 6.7e-07 29.2 0.0 1.8e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW72449.1 - 0.0021 17.6 1.2 0.0048 16.4 0.3 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Galactosyl_T PF01762.21 RJW72450.1 - 7.5e-09 35.7 0.1 6.2e-06 26.2 0.1 2.4 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 RJW72450.1 - 1.7e-05 24.4 0.2 0.00023 20.7 0.2 2.1 1 1 0 1 1 1 1 Fringe-like WD40 PF00400.32 RJW72451.1 - 2.5e-27 94.5 27.7 0.00017 22.3 0.1 10.1 10 0 0 10 10 10 7 WD domain, G-beta repeat HELP PF03451.14 RJW72451.1 - 2e-16 59.6 1.1 4.9e-16 58.4 1.1 1.6 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 RJW72451.1 - 3.3e-09 36.9 0.0 0.001 19.3 0.0 5.4 4 2 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RJW72451.1 - 0.046 13.1 0.0 6.7 5.9 0.1 2.8 2 1 1 3 3 3 0 WD40-like domain Mcl1_mid PF12341.8 RJW72451.1 - 0.14 11.5 0.0 0.85 8.9 0.0 2.1 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region BIR PF00653.21 RJW72452.1 - 9.4e-18 64.6 5.0 2.5e-17 63.3 5.0 1.8 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain DUF1041 PF06292.17 RJW72453.1 - 2.4e-30 105.0 0.3 2.4e-30 105.0 0.3 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) PH PF00169.29 RJW72453.1 - 3e-07 30.9 0.1 7.5e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 PH domain SWI-SNF_Ssr4 PF08549.10 RJW72453.1 - 1.4 7.5 9.0 2.3 6.8 9.0 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Cnl2_NKP2 PF09447.10 RJW72453.1 - 2.6 8.2 6.0 49 4.2 0.4 4.1 4 0 0 4 4 4 0 Cnl2/NKP2 family protein LRR_8 PF13855.6 RJW72454.1 - 1.2e-12 47.4 30.4 2.8e-06 27.0 3.6 4.9 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 RJW72454.1 - 2.6e-11 43.6 40.2 0.00087 19.6 0.5 6.7 3 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW72454.1 - 0.00015 21.3 8.5 0.065 12.7 0.3 3.2 1 1 1 2 2 2 2 Leucine-rich repeat Pkinase PF00069.25 RJW72455.1 - 1.4e-68 231.2 0.0 2.5e-68 230.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72455.1 - 3.8e-36 124.7 0.0 7.1e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW72455.1 - 7.4e-08 32.0 0.0 2.2e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RJW72455.1 - 0.023 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L27e PF01777.18 RJW72455.1 - 0.18 12.1 0.7 0.55 10.6 0.7 1.9 1 0 0 1 1 1 0 Ribosomal L27e protein family DEAD PF00270.29 RJW72457.1 - 1.7e-43 148.4 0.5 1.7e-43 148.4 0.5 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW72457.1 - 5.5e-30 104.0 0.3 7.8e-29 100.3 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RJW72457.1 - 6.1e-06 26.3 0.0 1.7e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 RJW72457.1 - 0.00014 21.7 0.1 0.00023 21.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RJW72457.1 - 0.00047 20.4 0.1 0.0012 19.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RJW72457.1 - 0.0025 18.1 1.4 0.0033 17.8 0.6 1.5 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 RJW72457.1 - 0.044 13.8 0.1 0.13 12.2 0.1 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.6 RJW72457.1 - 0.044 13.1 0.5 0.088 12.1 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF4844 PF16133.5 RJW72457.1 - 0.22 12.1 3.2 0.86 10.2 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4844) AKAP7_NLS PF10469.9 RJW72458.1 - 1.1e-20 74.4 0.0 1.6e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 RJW72458.1 - 1.3e-06 28.4 0.1 2.3e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 RJW72458.1 - 2.2e-05 25.1 0.0 4.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain LigT_PEase PF02834.16 RJW72458.1 - 5.3e-05 23.3 0.0 0.46 10.7 0.0 2.5 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 RJW72460.1 - 2.2e-21 76.7 0.0 3.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 RJW72460.1 - 0.057 13.6 0.0 14 6.0 0.0 2.4 2 1 0 2 2 2 0 LigT like Phosphoesterase HTH_Tnp_Tc5 PF03221.16 RJW72461.1 - 1.1e-09 38.2 0.0 2.5e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Kdo PF06293.14 RJW72461.1 - 1.8e-07 30.8 0.1 4.9e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RJW72461.1 - 9.5e-06 25.2 1.5 1.3e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 RJW72461.1 - 1.9e-05 24.7 7.6 0.00027 21.0 0.0 3.4 2 2 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 RJW72461.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 RJW72461.1 - 0.035 13.7 0.0 0.84 9.2 0.0 2.6 2 0 0 2 2 2 0 RIO1 family ATG16 PF08614.11 RJW72461.1 - 0.97 9.6 43.3 0.75 10.0 12.8 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 RJW72461.1 - 1.3 9.5 32.6 0.52 10.7 28.3 2.1 2 0 0 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 RJW72461.1 - 1.7 8.7 38.0 0.061 13.4 22.7 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 RJW72461.1 - 2.2 8.6 25.0 1.2 9.4 0.1 5.7 5 1 1 6 6 6 0 Homeobox associated leucine zipper Bacillus_HBL PF05791.11 RJW72461.1 - 2.3 8.0 11.4 2.8 7.7 1.8 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.11 RJW72461.1 - 2.5 8.6 9.3 0.54 10.7 0.5 3.5 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) CorA PF01544.18 RJW72461.1 - 5.3 6.3 13.3 21 4.3 12.6 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein MAD PF05557.13 RJW72461.1 - 5.6 5.2 35.0 0.62 8.4 18.4 2.6 2 1 1 3 3 3 0 Mitotic checkpoint protein Spc7 PF08317.11 RJW72461.1 - 6.4 5.6 32.3 1.5 7.6 26.7 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 RJW72461.1 - 6.9 5.2 19.3 1.5 7.4 14.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A TPR_1 PF00515.28 RJW72462.1 - 4.3e-45 149.8 22.9 3.6e-07 29.7 0.0 13.4 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_2 PF07719.17 RJW72462.1 - 2.6e-37 123.9 23.0 4.5e-05 23.2 0.0 14.7 16 0 0 16 16 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 RJW72462.1 - 3.4e-37 126.8 7.4 1.6e-07 31.7 0.2 9.7 6 1 2 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 RJW72462.1 - 3.4e-36 120.4 16.1 0.00018 21.5 0.0 12.9 13 1 0 13 13 12 7 Tetratricopeptide repeat TPR_14 PF13428.6 RJW72462.1 - 1.2e-26 91.1 12.7 0.012 16.4 0.0 13.0 10 4 4 14 14 14 6 Tetratricopeptide repeat TPR_16 PF13432.6 RJW72462.1 - 8.8e-23 80.7 4.0 5.4e-05 23.8 0.1 9.5 8 2 2 11 11 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 RJW72462.1 - 1e-22 78.8 22.1 0.011 16.1 0.0 14.0 15 1 0 15 15 13 5 Tetratricopeptide repeat TPR_12 PF13424.6 RJW72462.1 - 2.1e-21 76.0 29.1 0.00033 20.9 0.3 10.0 8 3 2 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 RJW72462.1 - 2.8e-19 68.5 5.5 0.0071 16.0 0.0 9.8 9 2 1 10 10 10 4 TPR repeat TPR_6 PF13174.6 RJW72462.1 - 4.7e-17 61.4 20.6 0.018 15.7 0.0 11.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 RJW72462.1 - 3.3e-14 51.8 20.7 0.24 11.5 0.0 11.9 13 1 0 13 13 12 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW72462.1 - 5.7e-10 39.3 12.3 0.0014 18.8 0.3 6.5 5 1 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RJW72462.1 - 2.9e-06 27.3 4.6 0.052 13.7 0.0 5.9 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 RJW72462.1 - 0.00024 21.4 0.0 6.7 7.7 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RJW72462.1 - 0.00076 19.3 28.5 0.031 14.2 0.1 9.5 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_3 PF07720.12 RJW72462.1 - 0.0026 17.7 18.9 0.23 11.5 3.2 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 RJW72462.1 - 0.007 16.4 1.9 3.3 7.9 0.3 4.1 4 0 0 4 4 4 1 Rapsyn N-terminal myristoylation and linker region DUF2225 PF09986.9 RJW72462.1 - 0.0091 15.7 0.1 0.0091 15.7 0.1 4.3 2 1 1 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) Vps39_1 PF10366.9 RJW72462.1 - 0.36 11.1 2.7 1.3 9.4 0.0 3.1 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 Fis1_TPR_C PF14853.6 RJW72462.1 - 1.4 9.1 13.6 16 5.7 0.1 5.5 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat GATA PF00320.27 RJW72463.1 - 3.3e-28 97.0 18.1 6.1e-15 54.5 4.9 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 RJW72463.1 - 0.00023 20.6 10.0 0.021 14.3 0.6 2.9 3 0 0 3 3 3 2 TFIIB zinc-binding CR6_interact PF10147.9 RJW72463.1 - 0.042 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Zn-ribbon_8 PF09723.10 RJW72463.1 - 0.082 13.0 1.4 13 6.0 0.1 2.9 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.13 RJW72463.1 - 0.15 12.1 2.8 1.6 8.9 0.2 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 RJW72463.1 - 0.38 10.2 6.8 0.14 11.6 0.4 3.0 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain RskA PF10099.9 RJW72463.1 - 0.64 10.3 6.8 0.48 10.7 0.8 3.2 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Auto_anti-p27 PF06677.12 RJW72463.1 - 1.3 9.3 10.2 1.1 9.5 0.4 2.9 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 RJW72463.1 - 5.8 6.8 6.0 8.2 6.3 1.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Glyco_hydro_38N PF01074.22 RJW72465.1 - 0.16 11.3 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain DUF1330 PF07045.11 RJW72466.1 - 2e-07 31.2 0.0 0.00028 21.2 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) ABM PF03992.16 RJW72466.1 - 0.015 15.4 0.4 0.52 10.5 0.1 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase MASE1 PF05231.14 RJW72467.1 - 0.083 12.0 0.3 0.096 11.8 0.3 1.2 1 0 0 1 1 1 0 MASE1 MMR_HSR1_Xtn PF16897.5 RJW72468.1 - 1.8e-26 92.2 0.4 3.2e-26 91.4 0.4 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 RJW72468.1 - 1.9e-18 66.6 0.0 6.1e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RJW72468.1 - 6.6e-10 38.7 0.0 2.3e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RJW72468.1 - 0.0092 16.1 0.1 3.2 7.8 0.0 2.3 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 RJW72468.1 - 0.012 14.6 0.1 0.1 11.5 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RRM_1 PF00076.22 RJW72469.1 - 4.5e-05 23.2 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Harakiri PF15196.6 RJW72469.1 - 0.11 12.9 0.4 0.21 12.1 0.4 1.4 1 0 0 1 1 1 0 Activator of apoptosis harakiri TES PF08034.11 RJW72471.1 - 4.6e-21 74.9 6.7 4.6e-21 74.9 6.7 6.0 7 1 0 7 7 7 2 Trematode eggshell synthesis protein EOS1 PF12326.8 RJW72473.1 - 0.14 12.0 0.0 3 7.7 0.0 2.1 2 0 0 2 2 2 0 N-glycosylation protein Troponin PF00992.20 RJW72474.1 - 4.7e-09 36.7 6.0 4.7e-09 36.7 6.0 2.9 2 1 1 3 3 3 1 Troponin Nup160 PF11715.8 RJW72475.1 - 7.6e-25 87.5 0.6 1.8e-18 66.5 0.5 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Arf PF00025.21 RJW72476.1 - 2.1e-58 196.6 0.0 2.5e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RJW72476.1 - 4.2e-12 46.3 0.0 5.4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RJW72476.1 - 1.1e-10 41.4 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RJW72476.1 - 2.5e-07 30.3 0.0 3.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RJW72476.1 - 6.9e-07 28.9 0.0 8.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RJW72476.1 - 1.3e-06 27.8 0.0 2.3e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit SpoOE-like PF09388.10 RJW72476.1 - 0.0053 16.6 0.5 0.0087 15.9 0.5 1.3 1 0 0 1 1 1 1 Spo0E like sporulation regulatory protein MMR_HSR1 PF01926.23 RJW72476.1 - 0.033 14.3 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase UCH PF00443.29 RJW72478.1 - 9.7e-51 172.7 2.4 1.3e-50 172.3 2.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW72478.1 - 8.8e-26 91.2 7.6 1.2e-25 90.8 7.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.16 RJW72479.1 - 4.9e-31 107.9 22.8 1e-30 106.9 22.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Arginase PF00491.21 RJW72479.1 - 7.2e-14 52.0 0.0 1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Arginase family Sugar_tr PF00083.24 RJW72479.1 - 1.4e-08 34.0 1.1 1.4e-08 34.0 1.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 RJW72479.1 - 0.01 14.5 8.8 0.047 12.2 1.5 2.6 3 0 0 3 3 3 0 MFS/sugar transport protein DUF2070 PF09843.9 RJW72479.1 - 0.081 11.2 0.4 0.14 10.4 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AAA_6 PF12774.7 RJW72480.1 - 1.2e-156 520.7 0.2 1.9e-155 516.8 0.0 3.0 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW72480.1 - 7.3e-138 460.0 8.8 7.3e-138 460.0 8.8 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RJW72480.1 - 1.3e-102 342.6 0.0 4.7e-102 340.8 0.0 2.1 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RJW72480.1 - 5.1e-90 300.4 2.0 5.1e-90 300.4 2.0 4.2 4 1 1 5 5 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 RJW72480.1 - 1.1e-68 230.3 0.0 1.7e-66 223.2 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region Dynein_C PF18199.1 RJW72480.1 - 4.2e-64 216.7 0.0 1.2e-63 215.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RJW72480.1 - 3e-63 212.5 0.1 3.3e-62 209.1 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 RJW72480.1 - 2.5e-49 168.2 8.1 7.4e-49 166.6 8.1 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RJW72480.1 - 1.8e-46 157.1 0.0 1.8e-43 147.4 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 RJW72480.1 - 1.5e-25 89.7 0.0 1.2e-24 86.8 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RJW72480.1 - 1.4e-19 70.4 0.0 1.8e-05 24.7 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RJW72480.1 - 2.6e-15 56.5 0.2 2.6e-13 50.0 0.3 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 RJW72480.1 - 6.7e-05 23.3 3.6 0.35 11.3 0.1 5.1 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RJW72480.1 - 0.0039 17.6 0.0 7.5 7.0 0.0 3.3 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 RJW72480.1 - 0.0053 17.3 0.0 0.2 12.2 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.6 RJW72480.1 - 0.0095 16.2 3.1 2.6 8.3 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 RJW72480.1 - 0.042 14.0 0.2 10 6.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 RJW72480.1 - 0.054 13.9 8.1 0.83 10.0 0.0 4.9 5 0 0 5 5 4 0 AAA ATPase domain ATPase_2 PF01637.18 RJW72480.1 - 0.11 12.4 3.5 0.28 11.0 0.0 3.4 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Ntox28 PF15605.6 RJW72480.1 - 7.8 6.8 7.2 5.4 7.3 0.0 3.8 3 0 0 3 3 3 0 Bacterial toxin 28 KxDL PF10241.9 RJW72480.1 - 9.2 6.6 9.1 3 8.2 0.7 4.2 3 0 0 3 3 3 0 Uncharacterized conserved protein RNA_pol_Rpb1_5 PF04998.17 RJW72481.1 - 1.9e-83 280.0 0.0 3.3e-83 279.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 RJW72481.1 - 5.4e-58 195.9 0.1 1.5e-57 194.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 RJW72481.1 - 2.9e-34 118.3 0.0 8.7e-34 116.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 RJW72481.1 - 1.6e-17 63.8 0.0 2.6e-16 59.8 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 RJW72481.1 - 6.7e-17 61.4 0.2 2.6e-16 59.5 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 TES PF08034.11 RJW72482.1 - 2.4e-22 79.0 14.2 2.4e-22 79.0 14.2 4.5 3 2 2 5 5 5 2 Trematode eggshell synthesis protein MukB PF04310.12 RJW72482.1 - 0.0058 16.5 0.8 0.0099 15.7 0.8 1.4 1 0 0 1 1 1 1 MukB N-terminal DDRGK PF09756.9 RJW72483.1 - 1.2e-57 194.5 25.0 1.9e-57 193.9 25.0 1.3 1 0 0 1 1 1 1 DDRGK domain SAGA-Tad1 PF12767.7 RJW72483.1 - 0.72 9.6 5.1 1.1 9.0 5.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2797 PF10977.8 RJW72483.1 - 0.88 9.4 8.3 1.4 8.7 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) RRM_1 PF00076.22 RJW72484.1 - 5.3e-06 26.2 0.1 1.3e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 RJW72484.1 - 0.0079 16.4 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 RRM_3 PF08777.11 RJW72484.1 - 0.0099 15.9 0.1 0.0099 15.9 0.1 2.1 2 0 0 2 2 2 1 RNA binding motif Sulfotransfer_4 PF17784.1 RJW72485.1 - 1.6e-60 204.7 0.0 1.8e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW72485.1 - 0.00022 21.7 0.7 0.11 12.9 0.0 2.9 2 1 1 3 3 3 2 Sulfotransferase family zf-HC5HC2H_2 PF13832.6 RJW72486.1 - 1.8e-34 118.2 4.1 1.8e-34 118.2 4.1 2.7 3 0 0 3 3 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RJW72486.1 - 4.2e-24 84.6 4.0 4.2e-24 84.6 4.0 3.0 3 0 0 3 3 2 1 PHD-like zinc-binding domain EPL1 PF10513.9 RJW72486.1 - 1.5e-22 80.6 2.4 1.5e-22 80.6 2.4 2.4 3 0 0 3 3 3 1 Enhancer of polycomb-like Bromodomain PF00439.25 RJW72486.1 - 4.1e-19 68.4 0.1 8.2e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 RJW72486.1 - 7.2e-14 51.1 3.4 7.2e-14 51.1 3.4 2.5 2 0 0 2 2 1 1 PHD-finger PWWP PF00855.17 RJW72486.1 - 4.7e-13 49.4 0.0 1.5e-12 47.7 0.0 2.0 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 RJW72486.1 - 1.7e-09 37.4 22.8 1.6e-07 31.1 9.1 2.8 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 RJW72486.1 - 0.006 16.4 2.4 0.006 16.4 2.4 2.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Sigma70_ECF PF07638.11 RJW72486.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 ECF sigma factor Zf_RING PF16744.5 RJW72486.1 - 0.36 11.0 15.1 1.5 9.0 4.6 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger C1_2 PF03107.16 RJW72486.1 - 0.43 10.9 16.9 0.35 11.2 4.9 3.1 3 0 0 3 3 2 0 C1 domain FAM183 PF14886.6 RJW72491.1 - 0.039 14.7 0.0 0.039 14.7 0.0 1.2 1 1 0 1 1 1 0 FAM183A and FAM183B related SPO11_like PF03533.14 RJW72492.1 - 0.022 14.8 0.0 8.2 6.6 0.0 2.2 2 0 0 2 2 2 0 SPO11 homologue CCDC85 PF10226.9 RJW72492.1 - 0.14 11.9 0.3 15 5.2 0.0 2.2 2 0 0 2 2 2 0 CCDC85 family DUF1841 PF08897.11 RJW72492.1 - 0.24 11.4 0.5 13 5.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1841) Pkinase PF00069.25 RJW72493.1 - 1.6e-48 165.4 0.0 3.9e-48 164.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72493.1 - 5.7e-24 84.8 0.0 1.1e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RJW72493.1 - 0.075 12.4 1.8 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW72493.1 - 0.081 12.8 0.0 0.081 12.8 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family SUIM_assoc PF16619.5 RJW72493.1 - 3.1 7.9 33.5 0.13 12.4 2.0 4.4 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 FAA_hydrolase PF01557.18 RJW72496.1 - 2.2e-50 171.3 0.0 2.5e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Herpes_heli_pri PF05774.11 RJW72496.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component DENN PF02141.21 RJW72497.1 - 3.3e-30 105.4 3.4 8.5e-30 104.1 3.4 1.7 1 1 0 1 1 1 1 DENN (AEX-3) domain SBF2 PF12335.8 RJW72497.1 - 0.026 14.1 0.1 0.077 12.6 0.1 1.8 1 0 0 1 1 1 0 Myotubularin protein Ribosomal_S8 PF00410.19 RJW72498.1 - 2.4e-12 46.9 0.0 3.3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 AIP3 PF03915.13 RJW72499.1 - 5.1e-16 58.8 0.9 5.1e-16 58.8 0.9 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 SKA2 PF16740.5 RJW72499.1 - 1.1 9.0 9.9 2 8.2 2.3 3.9 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DIRP PF06584.13 RJW72499.1 - 1.3 9.2 4.8 1.3 9.2 1.7 2.4 2 0 0 2 2 2 0 DIRP Golgin_A5 PF09787.9 RJW72499.1 - 1.6 8.1 15.0 0.34 10.4 6.0 2.8 2 1 0 2 2 2 0 Golgin subfamily A member 5 Fez1 PF06818.15 RJW72499.1 - 2.4 8.6 15.7 1.7 9.1 10.3 2.8 2 1 0 2 2 2 0 Fez1 GKAP PF03359.13 RJW72501.1 - 1.8e-12 47.5 3.9 3.1e-12 46.7 3.9 1.4 1 1 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein CCT PF06203.14 RJW72502.1 - 0.036 14.1 0.6 0.079 13.0 0.6 1.6 1 0 0 1 1 1 0 CCT motif DUF421 PF04239.12 RJW72502.1 - 0.2 11.4 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF421) PUFD PF16553.5 RJW72504.1 - 0.11 12.6 1.0 0.27 11.4 1.0 1.7 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain Xpo1 PF08389.12 RJW72505.1 - 3.7e-11 43.3 2.0 8.2e-11 42.2 0.1 2.7 4 0 0 4 4 4 1 Exportin 1-like protein SPRY PF00622.28 RJW72506.1 - 2.8e-14 53.3 0.5 7.8e-07 29.2 0.1 2.7 2 0 0 2 2 2 2 SPRY domain Zf_RING PF16744.5 RJW72506.1 - 0.2 11.8 0.5 1.1 9.4 0.2 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 RJW72506.1 - 1.3 9.0 8.8 5.6 6.9 7.4 2.4 1 1 1 2 2 2 0 PHD-finger Neur_chan_LBD PF02931.23 RJW72507.1 - 3.7e-32 111.5 0.3 2.8e-30 105.4 0.2 2.4 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RJW72507.1 - 2.7e-06 27.6 0.3 7e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 RJW72508.1 - 1.6e-13 50.1 27.2 6.3e-12 44.9 27.1 2.2 1 1 0 1 1 1 1 Macoilin family Trimer_CC PF08954.11 RJW72508.1 - 0.0025 17.4 0.1 0.0095 15.5 0.1 2.0 1 0 0 1 1 1 1 Trimerisation motif LURAP PF14854.6 RJW72508.1 - 0.65 10.0 4.7 0.88 9.5 1.9 2.7 2 1 0 2 2 2 0 Leucine rich adaptor protein IZUMO PF15005.6 RJW72508.1 - 0.77 10.3 9.2 0.13 12.7 2.0 2.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated ADH_N PF08240.12 RJW72509.1 - 1.3e-22 79.8 1.7 1.3e-22 79.8 1.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RJW72509.1 - 2.2e-22 79.4 0.1 4e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RJW72509.1 - 1.4e-05 24.7 0.0 5.8e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 RJW72509.1 - 0.0016 19.5 0.0 0.0028 18.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 RJW72509.1 - 0.088 12.4 0.3 0.14 11.7 0.3 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RT_RNaseH PF17917.1 RJW72510.1 - 0.0054 17.0 0.1 0.14 12.5 0.0 2.4 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RJW72510.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ADIP PF11559.8 RJW72511.1 - 0.01 16.0 11.6 0.01 16.0 11.6 7.6 3 1 2 7 7 7 3 Afadin- and alpha -actinin-Binding NIL PF09383.10 RJW72511.1 - 0.019 14.8 0.0 0.078 12.8 0.0 2.0 1 0 0 1 1 1 0 NIL domain ATG16 PF08614.11 RJW72511.1 - 0.14 12.3 111.4 0.16 12.2 23.5 7.2 1 1 6 7 7 7 0 Autophagy protein 16 (ATG16) ApbA_C PF08546.11 RJW72511.1 - 0.88 9.8 5.1 0.18 12.0 0.4 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Laminin_G_2 PF02210.24 RJW72512.1 - 1e-32 113.4 0.5 3.1e-21 76.2 0.3 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 RJW72512.1 - 3.1e-28 98.6 0.0 1.8e-22 80.0 0.0 2.6 2 1 0 2 2 2 2 Laminin G domain EGF PF00008.27 RJW72512.1 - 5.9e-12 45.7 32.1 0.00035 20.8 9.6 3.7 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 RJW72512.1 - 0.014 16.0 4.1 0.014 16.0 4.1 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF Laminin_G_3 PF13385.6 RJW72512.1 - 0.11 12.6 0.2 0.46 10.6 0.0 2.1 3 0 0 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily Laminin_EGF PF00053.24 RJW72512.1 - 0.32 11.2 33.1 0.3 11.2 2.0 3.4 3 0 0 3 3 3 0 Laminin EGF domain EGF_2 PF07974.13 RJW72512.1 - 1.8 9.0 37.1 3.9 7.9 5.7 3.8 3 1 0 3 3 3 0 EGF-like domain EGF_CA PF07645.15 RJW72512.1 - 3 8.1 35.2 4 7.7 4.5 3.5 3 0 0 3 3 3 0 Calcium-binding EGF domain EGF_3 PF12947.7 RJW72512.1 - 4.1 7.7 32.3 4.2 7.7 2.4 3.6 3 0 0 3 3 3 0 EGF domain Tektin PF03148.14 RJW72513.1 - 3e-109 365.3 30.7 4.1e-109 364.9 30.7 1.1 1 0 0 1 1 1 1 Tektin family RVT_1 PF00078.27 RJW72513.1 - 2.4e-14 53.4 0.0 5.4e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PI3K_P85_iSH2 PF16454.5 RJW72513.1 - 0.22 11.1 16.6 0.71 9.5 1.7 3.5 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain zf-C3HC PF07967.13 RJW72513.1 - 1.2 9.2 4.2 3.8 7.5 0.7 2.5 2 0 0 2 2 2 0 C3HC zinc finger-like Macoilin PF09726.9 RJW72515.1 - 7.5e-52 176.8 18.8 8.9e-52 176.6 18.8 1.0 1 0 0 1 1 1 1 Macoilin family Vmethyltransf PF01660.17 RJW72515.1 - 0.04 12.8 0.6 0.056 12.3 0.6 1.1 1 0 0 1 1 1 0 Viral methyltransferase Integrase_H2C2 PF17921.1 RJW72516.1 - 0.00017 21.6 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain PLAT PF01477.23 RJW72518.1 - 8.6e-05 23.1 0.0 0.00055 20.5 0.0 1.9 1 1 0 1 1 1 1 PLAT/LH2 domain MEIOC PF15189.6 RJW72520.1 - 1.7e-06 27.8 1.2 3.2e-06 26.9 1.2 1.4 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC SHE3 PF17078.5 RJW72520.1 - 0.041 13.6 0.2 0.073 12.8 0.2 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 IL10 PF00726.17 RJW72520.1 - 0.094 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Interleukin 10 Pih1_fungal_CS PF18482.1 RJW72521.1 - 0.053 14.1 0.0 0.074 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal Pih1 CS domain Aminotran_5 PF00266.19 RJW72522.1 - 0.0012 17.9 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RJW72522.1 - 0.1 11.1 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Zip PF02535.22 RJW72523.1 - 3.9e-73 246.5 11.2 2.5e-51 174.9 1.7 2.6 3 0 0 3 3 3 2 ZIP Zinc transporter Holin_9 PF16936.5 RJW72523.1 - 1.4 9.1 9.9 8.1 6.7 2.1 2.5 2 0 0 2 2 2 0 Putative holin DUF3325 PF11804.8 RJW72523.1 - 3 8.1 6.4 0.4 10.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Isochorismatase PF00857.20 RJW72527.1 - 1.7e-22 80.4 0.0 2.1e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Selenoprotein_S PF06936.11 RJW72528.1 - 4.6e-12 46.2 0.0 5.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) HrpB7 PF09486.10 RJW72528.1 - 0.00076 19.9 2.9 0.0011 19.3 2.9 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DUF648 PF04890.13 RJW72528.1 - 0.073 12.8 0.0 0.093 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) DEAD PF00270.29 RJW72529.1 - 2.5e-48 164.1 0.0 4.4e-47 160.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RJW72529.1 - 8.6e-27 93.7 0.2 3e-26 91.9 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 RJW72529.1 - 0.0029 16.9 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 RJW72529.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 RJW72529.1 - 0.081 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_30 PF13604.6 RJW72529.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain PRAI PF00697.22 RJW72529.1 - 0.18 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase UPF0506 PF11703.8 RJW72531.1 - 1.9e-17 63.4 24.2 2.2e-17 63.2 24.2 1.1 1 0 0 1 1 1 1 UPF0506 Conotoxin_I2 PF17557.2 RJW72531.1 - 0.13 12.4 20.8 0.33 11.1 7.9 2.4 2 1 0 2 2 2 0 I2-superfamily conotoxins 14-3-3 PF00244.20 RJW72532.1 - 4.2e-97 324.0 0.4 4.8e-97 323.8 0.4 1.0 1 0 0 1 1 1 1 14-3-3 protein SIKE PF05769.11 RJW72532.1 - 0.23 11.4 4.0 0.79 9.6 0.5 2.8 3 0 0 3 3 3 0 SIKE family tRNA-synt_1d PF00750.19 RJW72533.1 - 3.1e-133 444.0 0.0 3.7e-133 443.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 RJW72533.1 - 1.4e-29 102.7 0.0 2.7e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1e PF01406.19 RJW72533.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Peripla_BP_6 PF13458.6 RJW72533.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein WD40 PF00400.32 RJW72534.1 - 1.8e-30 104.5 9.2 3.8e-07 30.7 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Striatin PF08232.12 RJW72534.1 - 2e-28 100.0 7.0 2e-28 100.0 7.0 2.6 2 1 0 2 2 2 1 Striatin family ANAPC4_WD40 PF12894.7 RJW72534.1 - 7.5e-09 35.8 0.0 0.11 12.7 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW72534.1 - 2.4e-05 23.2 0.3 0.58 8.7 0.0 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 PA14 PF07691.12 RJW72534.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 PA14 domain Cadherin PF00028.17 RJW72536.1 - 3.2e-60 200.6 9.6 5.9e-10 39.5 0.0 11.2 7 4 0 7 7 7 6 Cadherin domain Cadherin_3 PF16184.5 RJW72536.1 - 9.1e-08 32.1 9.8 0.26 11.3 0.5 7.2 7 0 0 7 7 7 3 Cadherin-like Cadherin_4 PF17803.1 RJW72536.1 - 0.00021 21.9 1.0 4.4 8.0 0.3 4.6 4 0 0 4 4 4 2 Bacterial cadherin-like domain Big_9 PF17963.1 RJW72536.1 - 0.0017 19.1 4.1 0.95 10.2 0.5 4.5 4 0 0 4 4 4 1 Bacterial Ig domain Adeno_E3_CR2 PF02439.15 RJW72536.1 - 0.16 11.7 1.7 0.36 10.6 1.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Calycin_like PF13944.6 RJW72536.1 - 0.23 11.8 1.6 0.46 10.8 0.4 2.1 2 1 0 2 2 2 0 Calycin-like beta-barrel domain Thymidylat_synt PF00303.19 RJW72537.1 - 0.08 12.0 0.0 0.098 11.8 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase RRM_1 PF00076.22 RJW72539.1 - 8.2e-11 41.6 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RJW72539.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_1 PF14446.6 RJW72539.1 - 0.99 9.4 6.8 8.5 6.4 5.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ubiq-Cytc-red_N PF09165.10 RJW72539.1 - 7.6 7.5 17.2 6.7 7.7 4.0 3.5 3 1 0 3 3 3 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal adh_short PF00106.25 RJW72541.1 - 4.6e-36 124.1 0.0 8.3e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW72541.1 - 9.3e-16 58.1 0.0 1.5e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW72541.1 - 5.5e-09 36.2 0.1 2.2e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 KR domain Brix PF04427.18 RJW72542.1 - 1.8e-31 109.8 0.1 2.6e-31 109.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain PH_4 PF15404.6 RJW72542.1 - 0.12 12.1 0.7 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain ADAM_CR_2 PF17771.1 RJW72543.1 - 2.6e-14 53.5 27.0 9.4e-13 48.5 6.4 3.6 2 1 0 2 2 2 2 ADAM cysteine-rich domain Reprolysin PF01421.19 RJW72543.1 - 4.3e-08 33.3 0.5 8.4e-08 32.4 0.5 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 RJW72543.1 - 2.4e-05 24.4 1.7 2.4e-05 24.4 1.7 3.2 3 0 0 3 3 3 1 Thrombospondin type 1 domain Reprolysin_2 PF13574.6 RJW72543.1 - 0.002 18.1 0.9 0.0042 17.0 0.9 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RJW72543.1 - 0.015 15.4 4.3 0.028 14.6 4.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 RJW72543.1 - 0.023 14.4 1.0 0.053 13.2 1.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.8 RJW72543.1 - 0.04 13.6 0.1 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Tubulin PF00091.25 RJW72544.1 - 1.3e-65 221.3 0.0 1.9e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW72544.1 - 1.9e-41 141.2 0.0 3.2e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RJW72544.1 - 0.00032 21.0 0.0 0.00079 19.7 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain zf-C2HC PF01530.18 RJW72545.1 - 1e-19 70.4 18.0 8.5e-12 45.1 6.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2HC type RVT_1 PF00078.27 RJW72547.1 - 3.7e-34 118.2 0.0 6.1e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 RJW72547.1 - 0.0037 16.2 42.3 0.033 13.1 22.7 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily EF-hand_1 PF00036.32 RJW72549.1 - 3e-28 95.2 9.4 4.1e-07 29.1 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RJW72549.1 - 1.3e-24 83.9 4.3 5.8e-06 25.8 0.0 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RJW72549.1 - 3.7e-23 79.9 9.0 2.7e-06 26.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW72549.1 - 8.8e-21 74.1 8.3 5.9e-10 39.5 1.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RJW72549.1 - 9.8e-14 51.0 6.5 6.3e-06 25.9 0.4 3.7 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW72549.1 - 6.7e-09 36.1 3.7 7.5e-05 23.0 0.3 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RJW72549.1 - 1.5e-06 28.4 0.2 0.0067 16.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RJW72549.1 - 0.00018 21.4 5.8 0.21 11.6 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RJW72549.1 - 0.0054 16.9 0.0 0.66 10.2 0.0 3.0 3 0 0 3 3 3 1 Dockerin type I domain CesT PF05932.13 RJW72549.1 - 0.019 15.1 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family DUF2312 PF10073.9 RJW72549.1 - 0.02 14.6 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF3463 PF11946.8 RJW72549.1 - 0.051 13.4 0.2 2 8.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) EF-hand_10 PF14788.6 RJW72549.1 - 0.067 13.1 3.5 2.2 8.2 0.1 3.2 2 1 0 2 2 2 0 EF hand Pkinase PF00069.25 RJW72550.1 - 4.3e-26 91.9 0.0 4.3e-26 91.9 0.0 2.9 3 0 0 3 3 3 1 Protein kinase domain Filament PF00038.21 RJW72550.1 - 0.00034 20.3 40.0 0.00034 20.3 40.0 8.1 1 1 5 6 6 6 4 Intermediate filament protein DUF3800 PF12686.7 RJW72550.1 - 0.00044 20.9 2.8 2.4 8.8 0.6 5.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3800) DUF4201 PF13870.6 RJW72550.1 - 0.0025 17.6 14.7 0.0025 17.6 14.7 10.8 1 1 9 10 10 10 2 Domain of unknown function (DUF4201) APH PF01636.23 RJW72550.1 - 0.0029 17.5 0.0 0.0029 17.5 0.0 5.0 4 2 1 5 5 5 2 Phosphotransferase enzyme family Fez1 PF06818.15 RJW72550.1 - 0.0042 17.6 56.5 0.0069 16.9 21.1 9.9 1 1 7 8 8 8 3 Fez1 ATG16 PF08614.11 RJW72550.1 - 0.0099 16.1 226.6 0.18 12.0 21.0 11.1 2 2 7 9 9 9 7 Autophagy protein 16 (ATG16) T2SSG PF08334.11 RJW72550.1 - 8.6 6.5 7.2 33 4.6 0.1 4.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein G PAS_3 PF08447.12 RJW72552.1 - 5.2e-14 52.3 1.0 1.4e-08 34.9 0.1 2.7 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 RJW72552.1 - 1.1e-12 48.1 1.6 6.5e-10 39.1 0.4 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 RJW72552.1 - 1.6e-08 34.5 0.0 3.6e-07 30.2 0.0 2.7 2 0 0 2 2 2 1 PAS fold HLH PF00010.26 RJW72552.1 - 3.3e-07 30.1 0.4 8.6e-07 28.8 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 RJW72552.1 - 0.0043 17.3 0.0 0.043 14.1 0.0 2.5 2 1 0 2 2 2 1 PAS domain MerT PF02411.15 RJW72553.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 MerT mercuric transport protein HEAT_2 PF13646.6 RJW72554.1 - 2.3e-21 76.0 4.7 1.1e-09 38.5 0.2 3.6 2 2 1 3 3 3 2 HEAT repeats HEAT PF02985.22 RJW72554.1 - 8.9e-11 41.1 4.7 0.041 14.1 0.0 5.6 7 0 0 7 7 7 3 HEAT repeat HEAT_PBS PF03130.16 RJW72554.1 - 9.1e-11 41.4 9.7 0.0074 16.9 0.0 6.8 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 RJW72554.1 - 0.0021 18.5 10.2 1.3 9.6 0.3 5.6 5 2 1 6 6 6 3 HEAT-like repeat IFRD PF05004.13 RJW72554.1 - 0.035 13.2 0.0 1.2 8.2 0.0 2.5 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Scaffolding_pro PF11418.8 RJW72554.1 - 0.077 13.6 0.0 0.29 11.7 0.0 1.8 2 0 0 2 2 2 0 Phi29 scaffolding protein RRM_1 PF00076.22 RJW72556.1 - 3.7e-13 49.1 0.0 8.1e-08 32.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF684 PF05075.14 RJW72557.1 - 0.045 12.7 0.4 0.086 11.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF684) Atg14 PF10186.9 RJW72557.1 - 0.075 12.1 3.9 0.95 8.5 3.9 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spore_III_AB PF09548.10 RJW72557.1 - 0.076 13.1 0.1 0.35 11.0 0.1 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Spc7 PF08317.11 RJW72557.1 - 0.087 11.7 0.8 0.16 10.8 0.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein MFS_1 PF07690.16 RJW72558.1 - 1e-14 54.3 33.8 2.8e-06 26.5 1.9 3.4 3 1 0 3 3 3 3 Major Facilitator Superfamily DctQ PF04290.12 RJW72558.1 - 4.6 7.2 12.2 3 7.8 0.7 4.6 4 0 0 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component zf-CRD PF17979.1 RJW72559.1 - 3.9e-10 40.0 12.9 0.03 14.4 0.2 4.8 4 0 0 4 4 4 4 Cysteine rich domain with multizinc binding regions zf-C2H2_4 PF13894.6 RJW72559.1 - 0.0002 21.9 37.6 0.19 12.6 2.0 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger Porin_1 PF00267.21 RJW72559.1 - 0.068 12.6 0.1 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 Gram-negative porin zf-AN1 PF01428.16 RJW72559.1 - 0.31 11.3 25.0 0.043 14.0 1.7 4.8 4 0 0 4 4 4 0 AN1-like Zinc finger zf-C2H2 PF00096.26 RJW72559.1 - 4.7 7.9 40.1 0.15 12.6 1.7 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type Ank_4 PF13637.6 RJW72560.1 - 2.4e-25 88.5 6.0 6.3e-11 42.6 0.3 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RJW72560.1 - 3.4e-22 77.9 2.9 5e-09 36.2 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 RJW72560.1 - 7e-21 74.6 0.2 3e-16 59.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW72560.1 - 2.4e-17 61.2 0.3 0.00029 21.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RJW72560.1 - 4.7e-17 61.8 1.7 5.4e-10 39.3 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Peptidase_M16 PF00675.20 RJW72560.1 - 0.15 12.0 0.1 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) GSHPx PF00255.19 RJW72561.1 - 8.3e-29 99.3 0.0 1.1e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase YEATS PF03366.16 RJW72563.1 - 5.6e-20 71.1 0.2 1.1e-19 70.2 0.2 1.5 1 0 0 1 1 1 1 YEATS family Ribosomal_L30 PF00327.20 RJW72564.1 - 6.6e-20 70.7 0.8 1.7e-19 69.4 0.8 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 RJW72564.1 - 2.1e-13 50.3 11.2 4.3e-13 49.3 11.2 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain LSM PF01423.22 RJW72565.1 - 5.2e-09 35.7 0.0 8.7e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 LSM domain MATH PF00917.26 RJW72566.1 - 0.23 11.6 3.7 0.49 10.6 0.2 3.4 5 1 0 5 5 5 0 MATH domain RVT_1 PF00078.27 RJW72567.1 - 4.5e-08 32.9 0.0 6.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMIE PF16038.5 RJW72569.1 - 0.00037 20.3 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 TMIE protein EGF_2 PF07974.13 RJW72569.1 - 0.0037 17.6 2.5 0.013 15.9 2.5 1.9 1 1 0 1 1 1 1 EGF-like domain Adeno_E3_CR2 PF02439.15 RJW72569.1 - 0.0078 16.0 2.3 0.013 15.2 2.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 RJW72569.1 - 0.013 15.5 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 RJW72569.1 - 0.016 16.1 0.3 0.03 15.2 0.1 1.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 RJW72569.1 - 0.022 15.4 0.5 0.033 14.9 0.5 1.4 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MLANA PF14991.6 RJW72569.1 - 0.047 14.0 0.1 0.083 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein melan-A Vpu PF00558.19 RJW72569.1 - 0.072 12.9 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Vpu protein DUF3483 PF11982.8 RJW72569.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) MtrF PF09472.10 RJW72569.1 - 5.6 6.4 5.9 12 5.4 5.9 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Ras PF00071.22 RJW72570.1 - 1.6e-48 164.3 0.1 2.2e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW72570.1 - 1.2e-17 64.2 0.0 4.5e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW72570.1 - 1.9e-09 37.2 0.0 2.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RJW72570.1 - 0.0021 17.5 0.0 0.0066 15.9 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 RJW72570.1 - 0.0023 17.8 1.4 0.46 10.4 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RJW72570.1 - 0.0094 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 RJW72570.1 - 0.011 15.4 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 RJW72570.1 - 0.018 14.6 0.3 0.1 12.2 0.3 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 RJW72570.1 - 0.018 14.6 0.0 0.046 13.3 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 RJW72570.1 - 0.041 14.3 0.1 0.17 12.2 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 RJW72570.1 - 0.049 13.7 0.5 4.2 7.4 0.0 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 RJW72570.1 - 0.11 12.7 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF308 PF03729.13 RJW72571.1 - 0.0053 17.1 6.7 0.0076 16.6 6.7 1.2 1 0 0 1 1 1 1 Short repeat of unknown function (DUF308) Borrelia_P13 PF05628.12 RJW72571.1 - 0.011 15.7 0.6 0.014 15.4 0.6 1.1 1 0 0 1 1 1 0 Borrelia membrane protein P13 MFS_Mycoplasma PF07672.13 RJW72571.1 - 0.14 11.4 3.1 0.17 11.1 3.1 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter Phage_holin_3_6 PF07332.11 RJW72571.1 - 3.3 7.8 9.0 4.2 7.4 9.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Sec6 PF06046.13 RJW72579.1 - 2.3e-73 247.5 0.5 2.8e-73 247.2 0.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Bombinin PF05298.11 RJW72579.1 - 0.055 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Bombinin Baculo_p33 PF05214.12 RJW72580.1 - 0.0014 18.4 0.3 0.0027 17.5 0.3 1.4 1 0 0 1 1 1 1 Baculovirus P33 NAD_Gly3P_dh_C PF07479.14 RJW72581.1 - 7.2e-46 156.0 0.0 1.2e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 RJW72581.1 - 4.3e-40 137.3 0.0 7.5e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ion_trans PF00520.31 RJW72582.1 - 7.8e-30 103.9 5.7 1.1e-29 103.4 5.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RJW72582.1 - 1.3e-12 47.4 0.2 1.3e-12 47.4 0.2 2.9 4 0 0 4 4 4 1 Ion channel cNMP_binding PF00027.29 RJW72582.1 - 1.6e-09 37.7 0.0 9.3e-08 32.0 0.0 2.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain PAS_9 PF13426.7 RJW72582.1 - 3.2e-09 37.0 0.0 8.1e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 RJW72582.1 - 6.4e-06 26.2 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 RJW72582.1 - 0.0001 22.5 0.0 0.00074 19.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold RVT_1 PF00078.27 RJW72583.1 - 1.4e-06 28.0 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Snf7 PF03357.21 RJW72584.1 - 1.2e-22 80.4 17.2 1.2e-22 80.4 17.2 1.7 2 1 1 3 3 3 1 Snf7 Syntaxin-6_N PF09177.11 RJW72584.1 - 0.66 10.6 8.2 0.57 10.8 3.1 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal YscO-like PF16789.5 RJW72584.1 - 1.5 8.9 15.5 0.21 11.6 10.1 2.2 1 1 0 2 2 2 0 YscO-like protein BBL5 PF07289.11 RJW72585.1 - 1.7e-35 122.7 0.0 1.9e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein NUMOD3 PF07460.11 RJW72585.1 - 0.02 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) MRP-S26 PF14943.6 RJW72589.1 - 2.2e-17 63.5 0.6 2.6e-17 63.3 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 Isochorismatase PF00857.20 RJW72590.1 - 3.3e-30 105.6 0.6 6.1e-30 104.7 0.6 1.4 1 1 0 1 1 1 1 Isochorismatase family Ribosomal_L27A PF00828.19 RJW72591.1 - 3.2e-21 76.3 0.0 4.7e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A His_Me_b4a2 PF18275.1 RJW72592.1 - 0.013 15.6 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain NPR2 PF06218.11 RJW72594.1 - 1.1e-25 90.3 0.5 5.2e-14 51.8 0.2 4.3 4 1 0 4 4 4 3 Nitrogen permease regulator 2 Afi1 PF07792.12 RJW72594.1 - 0.0005 20.6 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Thiolase_N PF00108.23 RJW72596.1 - 3e-70 236.6 0.4 5.3e-70 235.7 0.3 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RJW72596.1 - 3.7e-30 104.1 0.0 7.9e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain SRR1 PF07985.12 RJW72596.1 - 8.1e-11 41.8 0.0 1.8e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 SRR1 ketoacyl-synt PF00109.26 RJW72596.1 - 0.0059 16.2 0.4 0.011 15.3 0.4 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Tubulin PF00091.25 RJW72598.1 - 6.3e-66 222.3 0.0 8.4e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW72598.1 - 3.2e-49 166.3 0.1 5.6e-49 165.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW72598.1 - 0.00027 20.7 0.0 0.00061 19.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Ank_2 PF12796.7 RJW72599.1 - 4.4e-74 245.1 28.0 2.4e-16 60.1 0.5 7.8 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW72599.1 - 2.6e-62 206.4 20.3 4.6e-12 46.2 0.1 10.1 5 2 6 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 RJW72599.1 - 7.6e-50 165.3 31.5 2.3e-06 27.8 0.2 12.7 13 0 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.6 RJW72599.1 - 1.1e-47 154.4 23.4 0.00071 19.8 0.0 12.8 13 0 0 13 13 13 9 Ankyrin repeat Ank_5 PF13857.6 RJW72599.1 - 4.4e-45 151.2 26.3 3.2e-07 30.5 0.1 11.9 5 4 7 12 12 12 11 Ankyrin repeats (many copies) Ion_trans PF00520.31 RJW72599.1 - 2.2e-07 30.3 19.6 3.2e-07 29.8 19.6 1.2 1 0 0 1 1 1 1 Ion transport protein Pex24p PF06398.11 RJW72599.1 - 0.29 10.1 11.9 0.55 9.2 11.9 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF4685 PF15737.5 RJW72600.1 - 0.005 17.3 0.4 0.017 15.5 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4685) Ribophorin_I PF04597.14 RJW72601.1 - 3.8e-122 408.7 0.2 5.2e-122 408.2 0.2 1.2 1 0 0 1 1 1 1 Ribophorin I MIB_HERC2 PF06701.13 RJW72601.1 - 0.16 12.2 0.0 0.43 10.9 0.0 1.6 1 0 0 1 1 1 0 Mib_herc2 Acyl-CoA_ox_N PF14749.6 RJW72601.1 - 0.26 11.8 3.0 0.69 10.5 3.0 1.8 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal CCDC-167 PF15188.6 RJW72601.1 - 6.7 7.1 9.3 2.2 8.7 1.2 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 GIY-YIG PF01541.24 RJW72603.1 - 0.016 15.5 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain OTU PF02338.19 RJW72604.1 - 6.5e-24 84.8 0.0 1.2e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.18 RJW72604.1 - 1e-08 34.3 37.0 0.00017 20.8 7.3 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others AnkUBD PF18418.1 RJW72604.1 - 1.1e-05 25.4 0.0 0.069 13.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin ubiquitin-binding domain DZR PF12773.7 RJW72604.1 - 0.00037 20.5 19.6 0.041 13.9 12.8 2.9 1 1 2 3 3 3 3 Double zinc ribbon ASC PF00858.24 RJW72605.1 - 4e-11 42.5 0.7 1.3e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel DUF5383 PF17355.2 RJW72605.1 - 0.0031 17.9 0.0 0.011 16.1 0.0 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5383) Bacillus_HBL PF05791.11 RJW72605.1 - 0.022 14.6 0.2 0.045 13.6 0.2 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) WD40 PF00400.32 RJW72607.1 - 1.6e-50 167.9 25.5 4.6e-08 33.6 0.0 9.3 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW72607.1 - 2.4e-15 56.6 3.0 0.045 14.0 0.0 6.4 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 RJW72607.1 - 3.1e-09 37.2 0.1 5.5e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 RJW72607.1 - 3.1e-08 33.0 0.0 0.061 12.3 0.0 4.8 4 2 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RJW72607.1 - 1.5e-06 27.2 1.6 1.7 7.2 0.0 4.1 3 1 1 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.11 RJW72607.1 - 0.033 14.1 0.0 0.35 10.7 0.0 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RJW72607.1 - 0.038 13.9 4.4 7.2 6.7 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 RJW72607.1 - 0.051 12.3 0.1 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like PHP_C PF13263.6 RJW72607.1 - 0.16 11.7 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 PHP-associated TFIIIC_delta PF12657.7 RJW72607.1 - 8.6 6.2 7.4 26 4.7 0.3 3.9 3 2 2 5 5 5 0 Transcription factor IIIC subunit delta N-term Vault_4 PF17796.1 RJW72608.1 - 0.097 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Major Vault Protein repeat domain DUF423 PF04241.15 RJW72608.1 - 0.15 12.3 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF423) DIRP PF06584.13 RJW72609.1 - 2.6e-33 114.4 0.5 6.6e-33 113.1 0.5 1.7 1 0 0 1 1 1 1 DIRP DUF764 PF05561.11 RJW72609.1 - 0.13 12.0 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) BBL5 PF07289.11 RJW72610.1 - 1.9e-24 86.3 0.0 2e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Ribosomal_L50 PF10501.9 RJW72611.1 - 0.042 14.0 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S Iso_dh PF00180.20 RJW72612.1 - 8.7e-65 219.1 0.0 1.2e-64 218.7 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase 7tm_1 PF00001.21 RJW72614.1 - 8.4e-48 163.0 22.8 1.1e-47 162.7 22.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RJW72614.1 - 8.1e-11 41.8 19.9 1.1e-10 41.3 19.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PSRT PF07636.11 RJW72614.1 - 0.025 14.3 0.9 0.06 13.0 0.9 1.6 1 0 0 1 1 1 0 PSRT Git3 PF11710.8 RJW72614.1 - 0.32 10.7 10.6 1.5 8.6 10.4 2.2 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 HLH PF00010.26 RJW72615.1 - 7.7e-15 54.6 1.5 2.2e-14 53.1 0.5 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain fn3_PAP PF17808.1 RJW72615.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Homeodomain PF00046.29 RJW72616.1 - 5.2e-24 83.9 4.7 7.6e-24 83.3 4.7 1.3 1 0 0 1 1 1 1 Homeodomain QLQ PF08880.11 RJW72616.1 - 0.00019 21.1 0.6 0.00032 20.4 0.6 1.3 1 0 0 1 1 1 1 QLQ KIAA1430 PF13879.6 RJW72617.1 - 0.0032 18.2 3.4 0.0032 18.2 3.4 2.7 2 1 0 2 2 2 1 KIAA1430 homologue NAC PF01849.18 RJW72618.1 - 1.8e-23 82.3 0.2 4.3e-23 81.0 0.1 1.7 2 0 0 2 2 2 1 NAC domain BRO1 PF03097.18 RJW72619.1 - 5.8e-64 216.3 0.3 1.4e-63 215.1 0.3 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 RJW72619.1 - 3.4e-54 184.1 16.8 6.6e-54 183.2 16.8 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV zf-C4H2 PF10146.9 RJW72619.1 - 0.22 11.8 10.8 0.25 11.6 5.0 2.6 2 1 0 2 2 2 0 Zinc finger-containing protein Kri1 PF05178.12 RJW72619.1 - 1.1 9.8 4.1 1.2 9.8 0.4 2.5 2 0 0 2 2 2 0 KRI1-like family V_ATPase_I PF01496.19 RJW72619.1 - 6.8 4.5 8.4 9.4 4.0 0.4 2.5 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family Glyco_hydro_31 PF01055.26 RJW72623.1 - 4.1e-101 339.3 1.0 5.4e-101 338.9 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 RJW72623.1 - 1.2e-24 86.3 1.0 9.3e-24 83.5 0.4 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like Vps39_1 PF10366.9 RJW72624.1 - 4.2e-05 23.8 1.0 0.37 11.1 0.1 3.3 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 RJW72624.1 - 0.0025 18.3 0.1 0.012 16.0 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 RJW72624.1 - 0.012 15.5 1.0 0.012 15.5 1.0 3.1 2 1 0 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.17 RJW72624.1 - 0.035 14.2 4.2 12 6.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RJW72624.1 - 0.58 10.5 2.6 64 3.9 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat MCM PF00493.23 RJW72625.1 - 5.7e-101 336.3 0.0 3.5e-100 333.7 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 RJW72625.1 - 5.6e-34 116.7 0.3 1.1e-33 115.8 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 RJW72625.1 - 1.2e-26 93.0 0.0 2.8e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 RJW72625.1 - 1.6e-26 92.5 1.4 4.5e-26 91.1 1.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RJW72625.1 - 4.4e-15 56.1 0.5 1.1e-14 54.9 0.1 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 RJW72625.1 - 3.2e-07 29.9 0.0 1.2e-06 28.0 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RJW72625.1 - 0.00022 21.1 0.0 0.00059 19.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RJW72625.1 - 0.00091 19.2 0.0 0.0025 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RJW72625.1 - 0.0025 17.5 0.0 0.0091 15.7 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM_bind PF09739.9 RJW72625.1 - 0.047 12.1 0.2 0.079 11.4 0.2 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor F-box-like PF12937.7 RJW72626.1 - 1.5e-08 34.4 3.2 4.3e-08 32.9 3.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 RJW72626.1 - 9.1e-06 25.3 17.2 1.1 9.5 0.1 8.0 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 RJW72626.1 - 2e-05 24.9 13.5 1.7 9.1 0.3 6.9 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW72626.1 - 0.13 12.9 21.2 3.7 8.5 0.2 8.3 8 1 0 8 8 8 0 Leucine Rich Repeat F-box PF00646.33 RJW72626.1 - 0.19 11.6 5.9 0.13 12.1 1.8 3.0 2 0 0 2 2 2 0 F-box domain SH3_9 PF14604.6 RJW72627.1 - 3.4e-18 65.2 0.3 3.4e-11 42.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 RJW72627.1 - 7.4e-17 61.2 0.0 1.7e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 RJW72627.1 - 4.9e-08 32.4 0.1 1.8e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 RJW72627.1 - 9e-08 31.7 0.1 0.0027 17.3 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain ALG3 PF05208.13 RJW72628.1 - 1.7e-131 438.9 21.2 2.1e-131 438.6 21.2 1.0 1 0 0 1 1 1 1 ALG3 protein Ank_2 PF12796.7 RJW72630.1 - 1.6e-61 204.9 22.8 7.8e-12 45.6 0.3 10.8 5 3 0 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW72630.1 - 5.3e-55 183.1 30.9 7.5e-09 36.0 0.2 15.7 10 5 6 17 17 17 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW72630.1 - 4.1e-45 146.6 42.0 0.0061 17.0 0.1 19.4 20 0 0 20 20 20 12 Ankyrin repeat Ank_5 PF13857.6 RJW72630.1 - 8.2e-38 128.0 32.2 7.2e-09 35.7 0.3 13.7 10 3 5 16 16 16 11 Ankyrin repeats (many copies) Ank PF00023.30 RJW72630.1 - 3.1e-34 115.9 38.9 0.0074 16.7 0.4 16.9 18 0 0 18 18 18 10 Ankyrin repeat FYVE PF01363.21 RJW72630.1 - 7e-17 61.3 6.9 1.7e-16 60.1 6.9 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RJW72630.1 - 0.13 12.5 4.6 0.31 11.3 4.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Arylsulfotrans PF05935.11 RJW72630.1 - 0.23 10.3 0.0 0.51 9.2 0.0 1.5 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) RVT_1 PF00078.27 RJW72631.1 - 8.3e-12 45.1 0.4 2.6e-11 43.5 0.4 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PP2C_2 PF13672.6 RJW72632.1 - 2e-05 24.3 0.9 9.1e-05 22.2 0.5 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C BBL5 PF07289.11 RJW72633.1 - 3.9e-19 68.9 0.1 7.8e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein KIP1 PF07765.12 RJW72633.1 - 0.14 12.3 0.0 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 KIP1-like protein PMM PF03332.13 RJW72634.1 - 1.5e-92 309.3 0.1 1.7e-92 309.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 RJW72634.1 - 0.068 12.9 0.0 1.1 9.0 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase G-patch_2 PF12656.7 RJW72635.1 - 0.084 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 G-patch domain PWI PF01480.17 RJW72636.1 - 2e-28 98.5 0.1 3.7e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 PWI domain DeoC PF01791.9 RJW72637.1 - 8.2e-19 68.1 0.0 1.1e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF4516 PF14990.6 RJW72637.1 - 0.012 15.3 0.4 0.026 14.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) CAP PF00188.26 RJW72639.1 - 1.7e-22 80.6 1.0 2.1e-22 80.3 1.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Tubulin PF00091.25 RJW72640.1 - 7e-68 228.7 0.0 9.4e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW72640.1 - 1.2e-50 170.9 0.0 1.9e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW72640.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain UCH PF00443.29 RJW72641.1 - 1.4e-41 142.7 0.2 7.7e-38 130.4 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW72641.1 - 1.7e-24 87.0 0.4 1.7e-24 87.0 0.4 2.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Asp PF00026.23 RJW72642.1 - 2.3e-119 398.5 0.2 2.7e-119 398.3 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW72642.1 - 3.1e-15 56.9 0.9 5.8e-13 49.5 0.9 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 RJW72642.1 - 2.5e-05 24.1 0.2 5.5e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.6 RJW72642.1 - 0.0093 16.6 0.1 0.54 10.9 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 RJW72642.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Pkinase PF00069.25 RJW72644.1 - 6.4e-15 55.2 0.0 8e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72644.1 - 3.6e-08 33.0 0.0 5.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase R3H-assoc PF13902.6 RJW72645.1 - 1.3e-19 70.9 0.1 2.9e-19 69.8 0.0 1.6 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 RJW72645.1 - 0.015 15.2 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 R3H domain Gaa1 PF04114.14 RJW72646.1 - 4e-35 121.8 0.0 1.4e-27 96.9 0.1 2.2 2 0 0 2 2 2 2 Gaa1-like, GPI transamidase component DUF4455 PF14643.6 RJW72646.1 - 0.0033 16.1 0.4 0.0047 15.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) UPRTase PF14681.6 RJW72647.1 - 4.6e-43 147.1 0.0 7.8e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 RJW72647.1 - 0.00072 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain His_Phos_2 PF00328.22 RJW72648.1 - 9.6e-23 81.1 0.0 1.4e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Gaa1 PF04114.14 RJW72649.1 - 4.8e-08 32.5 3.8 5.4e-08 32.3 3.8 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PDE4_UCR PF18100.1 RJW72650.1 - 1.4e-46 158.0 1.2 1.4e-46 158.0 1.2 1.7 2 0 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) PDEase_I PF00233.19 RJW72650.1 - 3.6e-19 69.5 3.5 3.6e-19 69.5 3.5 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Band_7 PF01145.25 RJW72651.1 - 3.3e-08 33.8 1.9 3.3e-08 33.8 1.9 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family Catalase-rel PF06628.12 RJW72651.1 - 0.16 12.2 1.6 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 Catalase-related immune-responsive Pkinase PF00069.25 RJW72653.1 - 1.5e-28 99.9 0.0 1.8e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72653.1 - 4.6e-16 58.9 0.0 5.6e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW72653.1 - 1.1e-10 40.9 0.0 1.3e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RJW72653.1 - 0.00033 20.6 0.0 0.00068 19.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RJW72653.1 - 0.014 14.8 0.0 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 RJW72653.1 - 0.04 12.9 0.2 0.062 12.3 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 RJW72653.1 - 0.082 12.3 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4528 PF15031.6 RJW72653.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) 5_nucleotid_C PF02872.18 RJW72654.1 - 1.2e-36 126.3 0.0 2.4e-36 125.3 0.0 1.5 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RJW72654.1 - 2.2e-07 31.6 0.1 3.6e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Myosin_tail_1 PF01576.19 RJW72655.1 - 0.38 8.5 7.6 0.026 12.3 1.1 2.0 2 0 0 2 2 2 0 Myosin tail DUF1640 PF07798.11 RJW72655.1 - 3.1 7.8 6.9 1.9 8.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) CLN3 PF02487.17 RJW72656.1 - 7e-07 28.6 0.0 7.8e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 CLN3 protein Ribosomal_L13 PF00572.18 RJW72659.1 - 0.0047 17.2 0.0 0.023 15.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L13 PHM7_cyt PF14703.6 RJW72661.1 - 7.8e-32 110.9 0.0 2e-31 109.6 0.0 1.6 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 RJW72661.1 - 2.6e-10 40.1 11.3 2.6e-10 40.1 11.3 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 RJW72661.1 - 9.5e-07 28.7 0.3 9.5e-07 28.7 0.3 2.9 3 2 0 3 3 3 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 RJW72661.1 - 0.039 13.8 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_13 PF17977.1 RJW72661.1 - 0.11 12.6 6.7 0.24 11.6 6.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YMF19 PF02326.15 RJW72661.1 - 3.6 8.4 6.8 0.75 10.6 0.5 2.4 2 0 0 2 2 2 0 Plant ATP synthase F0 EF-hand_6 PF13405.6 RJW72664.1 - 1.5e-11 43.3 0.5 7.3e-05 22.4 0.3 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 RJW72664.1 - 1.9e-11 42.6 4.8 0.00058 19.2 0.6 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RJW72664.1 - 3.9e-10 40.0 0.5 0.00052 20.4 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair UPF0154 PF03672.13 RJW72664.1 - 0.00088 19.3 0.0 0.74 9.9 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_8 PF13833.6 RJW72664.1 - 0.0016 18.3 2.7 0.052 13.4 0.1 3.5 1 1 3 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 RJW72664.1 - 0.0043 16.5 0.9 3.8 7.2 0.0 2.7 2 0 0 2 2 2 2 EF hand DUF5613 PF18467.1 RJW72664.1 - 0.079 13.4 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) DDE_Tnp_IS66_C PF13817.6 RJW72664.1 - 0.2 11.9 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 0 IS66 C-terminal element COPIIcoated_ERV PF07970.12 RJW72668.1 - 4.7e-41 141.1 0.0 5.9e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter FHA PF00498.26 RJW72669.1 - 1.5e-10 41.3 0.3 3.7e-10 40.0 0.2 1.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 RJW72669.1 - 0.0021 18.4 0.0 0.0042 17.4 0.0 1.6 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FlaC_arch PF05377.11 RJW72670.1 - 0.15 12.5 14.7 0.37 11.2 0.3 4.8 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 RJW72670.1 - 0.21 10.5 38.0 0.12 11.3 9.1 3.2 2 2 2 4 4 4 0 Spc7 kinetochore protein DUF2730 PF10805.8 RJW72670.1 - 0.39 10.8 13.2 4.5 7.4 2.2 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) DUF3584 PF12128.8 RJW72670.1 - 0.82 7.1 28.6 0.8 7.1 8.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TRAF_BIRC3_bd PF16673.5 RJW72670.1 - 1.1 9.1 11.4 1.8 8.4 0.4 3.4 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain CENP-F_leu_zip PF10473.9 RJW72670.1 - 1.5 8.8 36.0 3.2 7.8 7.6 5.3 3 2 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DAP PF15228.6 RJW72670.1 - 5.4 8.3 6.7 0.68 11.1 1.1 2.5 2 1 1 3 3 3 0 Death-associated protein APG6_N PF17675.1 RJW72670.1 - 5.6 7.5 40.3 0.46 11.0 7.9 4.0 3 1 1 4 4 4 0 Apg6 coiled-coil region GTP_EFTU_D2 PF03144.25 RJW72671.1 - 2.4e-07 31.0 0.0 5.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Peptidase_S8 PF00082.22 RJW72674.1 - 3.7e-40 138.0 3.0 4.8e-40 137.7 3.0 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 RJW72674.1 - 4e-22 78.0 0.1 8.2e-22 77.0 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 RJW72674.1 - 1.6e-13 51.2 0.5 3.7e-13 50.0 0.5 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain SH2 PF00017.24 RJW72675.1 - 1.7e-06 28.0 0.0 3.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Peptidase_M17 PF00883.21 RJW72676.1 - 5.4e-58 196.7 0.2 7.5e-58 196.2 0.2 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain RhoGEF PF00621.20 RJW72677.1 - 8.7e-36 123.9 3.5 1.7e-35 122.9 3.5 1.5 1 0 0 1 1 1 1 RhoGEF domain WD40 PF00400.32 RJW72678.1 - 9.4e-06 26.3 19.2 0.26 12.2 1.5 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat WH1 PF00568.23 RJW72679.1 - 5.2e-25 87.6 0.1 1e-24 86.6 0.1 1.4 1 0 0 1 1 1 1 WH1 domain DUF2076 PF09849.9 RJW72679.1 - 0.012 15.6 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FERM_M PF00373.18 RJW72680.1 - 1.3e-17 64.3 0.1 4.1e-17 62.7 0.1 1.8 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 RJW72680.1 - 1.7e-07 31.5 0.4 3.9e-07 30.4 0.4 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 RJW72680.1 - 1.2e-06 28.4 0.1 2.2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain Di19_C PF14571.6 RJW72680.1 - 0.17 12.4 2.6 0.76 10.3 2.6 2.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Integrase_H2C2 PF17921.1 RJW72683.1 - 9.4e-11 41.7 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain GATA PF00320.27 RJW72684.1 - 4.7e-17 61.3 17.5 5e-14 51.6 6.9 2.9 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 RJW72684.1 - 0.018 14.5 8.3 0.31 10.6 1.0 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding Toxin_4 PF00706.17 RJW72684.1 - 0.065 13.7 0.5 0.18 12.3 0.5 1.8 1 0 0 1 1 1 0 Anenome neurotoxin RskA PF10099.9 RJW72684.1 - 0.12 12.7 0.5 8.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF2387 PF09526.10 RJW72684.1 - 0.31 11.2 4.5 2 8.6 0.1 3.0 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) DZR PF12773.7 RJW72684.1 - 2.5 8.2 6.7 19 5.4 1.1 3.1 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 RJW72684.1 - 5.1 7.3 6.2 5.4 7.2 0.2 3.0 2 1 1 3 3 3 0 Zinc ribbon domain TUDOR PF00567.24 RJW72686.1 - 1.2e-09 38.2 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Tudor domain RtcB PF01139.17 RJW72687.1 - 1.7e-141 472.2 0.1 2.3e-141 471.7 0.1 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB RVT_1 PF00078.27 RJW72687.1 - 1.1e-16 61.0 0.0 2.1e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mannosyl_trans2 PF04188.13 RJW72688.1 - 1.4e-57 196.0 15.4 2.5e-56 191.9 15.4 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Zip PF02535.22 RJW72689.1 - 6.1e-39 134.2 14.2 2.1e-32 112.7 2.4 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter HCV_core PF01542.18 RJW72689.1 - 0.061 13.7 0.2 0.34 11.3 0.0 2.3 2 0 0 2 2 2 0 Hepatitis C virus core protein UPF0016 PF01169.19 RJW72689.1 - 0.39 11.1 2.6 2.4 8.6 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 RIX1 PF08167.12 RJW72690.1 - 0.015 15.0 0.9 0.044 13.5 0.1 2.2 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Herpes_UL47 PF03362.13 RJW72690.1 - 0.04 12.7 0.0 1.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus UL47 protein UME PF08064.13 RJW72690.1 - 0.056 13.4 0.1 0.23 11.4 0.1 2.1 1 1 0 1 1 1 0 UME (NUC010) domain HEAT_EZ PF13513.6 RJW72690.1 - 0.31 11.6 5.5 4.4 7.9 0.1 4.2 2 1 2 4 4 4 0 HEAT-like repeat Ion_trans PF00520.31 RJW72691.1 - 7.1e-08 32.0 2.9 9.1e-08 31.6 2.9 1.1 1 0 0 1 1 1 1 Ion transport protein DUF2151 PF10221.9 RJW72692.1 - 6.4e-77 259.7 0.0 8.8e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Cell cycle and development regulator Ras PF00071.22 RJW72695.1 - 2.3e-51 173.6 0.0 5.5e-51 172.4 0.0 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW72695.1 - 6e-32 110.4 0.0 1.5e-31 109.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW72695.1 - 3.2e-15 56.0 0.1 3.2e-15 56.0 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_6 PF13405.6 RJW72695.1 - 1.1e-07 31.2 0.9 0.0011 18.7 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain MMR_HSR1 PF01926.23 RJW72695.1 - 1.7e-07 31.3 0.0 5.7e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 RJW72695.1 - 5.7e-07 28.6 0.2 9.9e-05 21.6 0.0 2.6 2 0 0 2 2 2 1 EF hand Gtr1_RagA PF04670.12 RJW72695.1 - 4.1e-06 26.3 0.0 1.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_7 PF13499.6 RJW72695.1 - 5.4e-06 26.8 0.2 2.7e-05 24.6 0.2 2.3 1 0 0 1 1 1 1 EF-hand domain pair GTP_EFTU PF00009.27 RJW72695.1 - 8.9e-06 25.4 0.0 2.9e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EF-hand_8 PF13833.6 RJW72695.1 - 1e-05 25.3 0.2 0.00037 20.3 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain pair SRPRB PF09439.10 RJW72695.1 - 0.00015 21.2 0.9 0.00052 19.5 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 RJW72695.1 - 0.0002 21.3 0.0 0.87 9.5 0.0 3.0 2 0 0 2 2 2 2 RsgA GTPase EF-hand_5 PF13202.6 RJW72695.1 - 0.0011 18.3 0.5 0.004 16.6 0.1 2.1 2 0 0 2 2 2 1 EF hand AAA_25 PF13481.6 RJW72695.1 - 0.03 13.9 0.5 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1326 PF07040.11 RJW72695.1 - 0.11 12.5 0.7 0.28 11.2 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) PduV-EutP PF10662.9 RJW72695.1 - 0.15 11.8 0.1 3.3 7.5 0.1 3.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GIT_CC PF16559.5 RJW72695.1 - 0.33 10.9 7.4 1.1 9.1 0.2 2.9 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_16 PF13191.6 RJW72695.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.2 3 1 0 3 3 2 0 AAA ATPase domain TPR_MLP1_2 PF07926.12 RJW72695.1 - 4.2 7.4 28.7 0.16 12.1 6.2 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cep57_MT_bd PF06657.13 RJW72695.1 - 5.1 7.6 16.1 0.31 11.5 2.2 3.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Mod_r PF07200.13 RJW72695.1 - 5.6 7.1 25.4 0.28 11.3 9.2 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Hairy_orange PF07527.13 RJW72695.1 - 6.7 7.0 6.1 4.1 7.7 0.1 3.1 3 0 0 3 3 2 0 Hairy Orange APH PF01636.23 RJW72695.1 - 8.6 6.2 7.1 17 5.3 6.3 2.0 2 1 0 2 2 1 0 Phosphotransferase enzyme family Sterol-sensing PF12349.8 RJW72696.1 - 1e-42 145.6 9.7 1.9e-42 144.7 9.7 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 RJW72696.1 - 2.7e-15 55.5 9.7 4.2e-15 54.9 9.7 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 RJW72696.1 - 0.25 12.3 5.6 11 7.1 0.1 4.1 3 0 0 3 3 3 0 WD domain, G-beta repeat PIG-P PF08510.12 RJW72696.1 - 0.51 10.3 2.5 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 PIG-P AARP2CN PF08142.12 RJW72697.1 - 2.5e-22 78.8 0.0 2.1e-21 75.8 0.0 2.5 3 0 0 3 3 3 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 RJW72697.1 - 0.00025 20.6 0.0 0.028 14.0 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 RJW72697.1 - 0.00068 19.9 0.7 0.29 11.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 RJW72697.1 - 0.0081 16.2 0.1 0.056 13.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 RJW72697.1 - 0.0093 15.9 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 RJW72697.1 - 0.018 15.4 0.0 0.018 15.4 0.0 2.6 3 2 0 3 3 1 0 AAA ATPase domain AAA PF00004.29 RJW72697.1 - 0.023 15.1 0.1 0.055 13.9 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 RJW72697.1 - 0.031 13.3 0.1 0.055 12.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 RJW72697.1 - 0.036 13.7 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 RJW72697.1 - 0.036 14.6 0.1 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 RJW72697.1 - 0.046 14.1 0.1 0.14 12.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RJW72697.1 - 0.046 13.9 0.3 0.23 11.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 RJW72697.1 - 0.047 13.6 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 RJW72697.1 - 0.068 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RJW72697.1 - 0.13 11.8 0.4 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RJW72697.1 - 0.14 12.7 0.1 0.37 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 RJW72697.1 - 0.27 11.0 0.6 0.77 9.5 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 RJW72697.1 - 0.31 11.3 0.0 0.31 11.3 0.0 2.4 3 0 0 3 3 2 0 AAA domain FLYWCH PF04500.16 RJW72699.1 - 0.028 14.5 4.8 0.081 13.0 0.3 2.9 3 0 0 3 3 3 0 FLYWCH zinc finger domain F-actin_cap_A PF01267.17 RJW72702.1 - 2e-64 217.6 0.0 2.2e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit LptC PF06835.13 RJW72704.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide-assembly, LptC-related NEMP PF10225.9 RJW72705.1 - 3.8e-12 46.4 8.7 7.8e-12 45.4 8.7 1.5 1 0 0 1 1 1 1 NEMP family TrbE PF11100.8 RJW72705.1 - 0.032 14.4 1.4 2 8.7 0.1 3.3 2 0 0 2 2 2 0 Conjugal transfer protein TrbE PHD PF00628.29 RJW72706.1 - 3.5e-15 55.6 24.0 1.2e-08 34.7 6.7 2.5 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 RJW72706.1 - 0.00052 19.5 0.6 0.00052 19.5 0.6 2.8 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 RJW72706.1 - 0.04 13.8 20.8 0.52 10.2 4.0 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Requiem_N PF14051.6 RJW72706.1 - 0.067 13.4 0.7 0.28 11.4 0.2 2.3 2 0 0 2 2 2 0 N-terminal domain of DPF2/REQ. RAG2_PHD PF13341.6 RJW72706.1 - 0.2 11.7 3.8 0.15 12.2 1.1 2.0 1 1 1 2 2 2 0 RAG2 PHD domain PHD_4 PF16866.5 RJW72706.1 - 0.86 9.7 22.7 1.9 8.7 11.4 3.2 1 1 1 2 2 2 0 PHD-finger zf-MIZ PF02891.20 RJW72706.1 - 3.9 7.3 16.9 12 5.7 10.7 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger HEAT PF02985.22 RJW72707.1 - 8.2e-23 78.5 29.1 0.0077 16.4 0.0 15.9 18 0 0 18 18 17 6 HEAT repeat HEAT_2 PF13646.6 RJW72707.1 - 8.7e-18 64.5 17.6 0.0017 18.7 0.4 8.7 3 2 6 9 9 9 6 HEAT repeats HEAT_EZ PF13513.6 RJW72707.1 - 1.9e-16 60.2 28.5 0.00096 19.6 0.1 11.7 12 2 2 14 14 12 4 HEAT-like repeat Cnd1 PF12717.7 RJW72707.1 - 1.8e-10 41.1 0.1 0.31 11.1 0.0 7.8 7 2 1 9 9 9 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 RJW72707.1 - 1.7e-07 31.1 0.0 0.014 15.0 0.0 4.9 4 1 1 5 5 5 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 RJW72707.1 - 1.7e-07 31.7 0.0 16 6.2 0.0 6.7 6 1 2 8 8 7 0 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 RJW72707.1 - 2.5e-06 27.3 0.1 0.0017 17.9 0.0 4.2 3 0 0 3 3 3 1 Tti2 family Adaptin_N PF01602.20 RJW72707.1 - 3.5e-06 25.9 0.0 1.7 7.1 0.0 5.8 5 1 1 6 6 6 2 Adaptin N terminal region NUC173 PF08161.12 RJW72707.1 - 4.5e-05 23.2 0.0 0.85 9.2 0.0 3.8 3 0 0 3 3 3 2 NUC173 domain UME PF08064.13 RJW72707.1 - 5.1e-05 23.1 1.9 2.3 8.2 0.1 5.9 5 2 2 7 7 7 2 UME (NUC010) domain DUF3385 PF11865.8 RJW72707.1 - 0.001 19.0 1.5 1.1 9.1 0.1 6.0 6 1 0 7 7 7 1 Domain of unknown function (DUF3385) ParcG PF10274.9 RJW72707.1 - 0.0053 16.9 1.4 20 5.3 0.0 5.2 5 1 0 5 5 5 0 Parkin co-regulated protein GyrB_insert PF18053.1 RJW72707.1 - 0.32 10.9 3.0 0.88 9.4 3.0 1.7 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain DNA_pol_phi PF04931.13 RJW72707.1 - 0.56 8.3 30.2 0.69 8.0 21.1 4.0 5 0 0 5 5 5 0 DNA polymerase phi DUF2040 PF09745.9 RJW72707.1 - 0.87 9.7 8.7 0.045 13.8 2.8 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Pes-10 PF07149.11 RJW72707.1 - 3.1 6.8 9.5 6.3 5.8 9.5 1.4 1 0 0 1 1 1 0 Pes-10 Arm PF00514.23 RJW72707.1 - 4.3 7.5 9.3 23 5.2 0.1 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat PI3_PI4_kinase PF00454.27 RJW72708.1 - 4.4e-53 180.7 0.0 5.7e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Toxin_16 PF07945.11 RJW72708.1 - 0.093 12.6 5.4 0.18 11.7 5.4 1.4 1 0 0 1 1 1 0 Janus-atracotoxin TSP_1 PF00090.19 RJW72711.1 - 1.1e-06 28.7 7.7 1.1e-06 28.7 7.7 3.5 3 1 0 3 3 3 2 Thrombospondin type 1 domain RRM_7 PF16367.5 RJW72712.1 - 9e-37 125.1 0.0 1.9e-35 120.9 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 RJW72712.1 - 3.4e-20 72.0 6.5 3.4e-20 72.0 6.5 2.9 4 0 0 4 4 4 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 RJW72712.1 - 3.9e-10 39.4 0.0 4.4e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OprF PF05736.11 RJW72712.1 - 0.072 12.8 0.3 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 OprF membrane domain zf-B_box PF00643.24 RJW72712.1 - 0.15 12.3 6.6 0.45 10.7 6.6 1.8 1 0 0 1 1 1 0 B-box zinc finger RIBIOP_C PF04950.12 RJW72713.1 - 1.6e-64 218.2 0.7 1.9e-64 217.9 0.0 1.4 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal ADIP PF11559.8 RJW72713.1 - 0.23 11.5 7.9 0.39 10.8 7.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2615 PF11027.8 RJW72714.1 - 1.3e-25 89.6 0.0 1.5e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) zf-C2H2 PF00096.26 RJW72717.1 - 2.7e-13 49.6 19.4 1.7e-05 25.0 2.8 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW72717.1 - 8e-11 41.9 7.5 1.2e-07 31.9 1.8 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW72717.1 - 3.3e-08 33.7 15.1 0.0018 18.9 1.5 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW72717.1 - 1.3e-06 28.3 4.4 0.00036 20.4 0.5 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW72717.1 - 0.0064 16.7 4.6 0.04 14.2 0.3 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW72717.1 - 0.027 14.9 0.8 0.12 12.8 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1179 PF06678.11 RJW72717.1 - 0.33 11.0 4.3 0.18 11.8 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Evr1_Alr PF04777.13 RJW72717.1 - 0.35 11.4 4.7 1.2 9.6 0.2 2.6 1 1 1 2 2 2 0 Erv1 / Alr family zf-C2H2_8 PF15909.5 RJW72717.1 - 2 8.7 11.3 0.28 11.5 1.5 3.2 2 2 1 3 3 3 0 C2H2-type zinc ribbon Ion_trans PF00520.31 RJW72718.1 - 7.8e-10 38.4 0.7 1.1e-09 37.9 0.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ig_3 PF13927.6 RJW72719.1 - 2.7e-05 24.7 0.0 0.0017 18.9 0.0 3.7 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RJW72719.1 - 8.7e-05 22.5 0.0 0.23 11.6 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 RJW72719.1 - 0.00027 21.1 0.1 1.5 9.0 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 RJW72719.1 - 0.0069 16.5 0.1 0.17 12.0 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin V-set domain zinc_ribbon_16 PF17034.5 RJW72720.1 - 0.033 14.4 0.1 0.043 14.0 0.1 1.1 1 0 0 1 1 1 0 Zinc-ribbon like family PEP-utilisers_N PF05524.13 RJW72721.1 - 0.14 12.4 5.6 3.4 7.9 0.6 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1843 PF08898.10 RJW72721.1 - 0.33 11.5 0.1 0.33 11.5 0.1 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) DUF4298 PF14131.6 RJW72721.1 - 0.69 9.9 2.8 0.73 9.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) T2SSM PF04612.12 RJW72721.1 - 1.3 9.1 7.7 4.7 7.2 0.8 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DASH_Duo1 PF08651.10 RJW72721.1 - 1.4 8.7 6.3 0.44 10.3 1.1 2.4 2 1 0 2 2 2 0 DASH complex subunit Duo1 DHR-2 PF06920.13 RJW72723.1 - 1.5e-21 76.7 0.1 4.8e-21 75.0 0.1 1.7 1 1 0 1 1 1 1 Dock homology region 2 Coa1 PF08695.10 RJW72725.1 - 0.048 13.4 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 FBPase_glpX PF03320.13 RJW72725.1 - 0.15 10.9 0.6 0.61 8.9 0.2 1.8 2 0 0 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Tubulin PF00091.25 RJW72726.1 - 7.9e-54 182.9 0.1 1e-51 175.9 0.1 2.2 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW72726.1 - 6.2e-29 100.7 0.3 1.4e-28 99.6 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Ephrin_rec_like PF07699.13 RJW72727.1 - 3.1e-09 36.4 4.1 3.1e-09 36.4 4.1 2.8 2 1 1 3 3 3 1 Putative ephrin-receptor like NCD3G PF07562.14 RJW72727.1 - 0.026 14.5 3.9 0.1 12.6 1.1 2.5 1 1 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR SNF PF00209.18 RJW72728.1 - 2.3e-130 435.8 36.0 2.7e-130 435.6 36.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ephrin_rec_like PF07699.13 RJW72729.1 - 7.8e-08 32.0 4.8 7.8e-08 32.0 4.8 2.9 3 0 0 3 3 3 1 Putative ephrin-receptor like NCD3G PF07562.14 RJW72729.1 - 0.02 14.8 4.0 0.058 13.4 0.4 2.7 2 1 2 4 4 4 0 Nine Cysteines Domain of family 3 GPCR zf-C2H2 PF00096.26 RJW72730.1 - 2.1e-15 56.2 48.9 0.00021 21.6 1.0 7.2 7 1 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RJW72730.1 - 4.6e-12 45.5 22.9 3.3e-10 39.5 0.4 5.8 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RJW72730.1 - 4.7e-10 39.4 40.5 0.0002 21.7 2.7 7.1 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW72730.1 - 4.4e-08 33.3 48.2 0.05 14.5 0.3 7.8 8 0 0 8 8 7 4 C2H2-type zinc finger zf-C2HE PF16278.5 RJW72730.1 - 0.00089 19.7 0.6 0.00089 19.7 0.6 4.3 3 2 2 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_aberr PF17017.5 RJW72730.1 - 0.02 15.1 5.0 0.56 10.3 3.7 2.5 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 RJW72730.1 - 0.046 14.0 17.6 1.5 9.2 0.5 5.4 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-DNA_Pol PF08996.10 RJW72730.1 - 0.33 10.7 11.7 0.06 13.1 5.5 2.5 2 1 1 3 3 3 0 DNA Polymerase alpha zinc finger zf-met PF12874.7 RJW72730.1 - 0.54 10.7 23.2 0.56 10.7 1.3 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.6 RJW72730.1 - 0.77 9.7 9.0 7.3 6.6 0.3 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RJW72730.1 - 0.99 10.2 9.1 2.9 8.7 1.9 2.9 2 1 1 3 3 3 0 zinc-ribbon family PriA_CRR PF18319.1 RJW72730.1 - 2.4 8.2 13.4 17 5.5 1.8 4.2 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain Spt46 PF17734.1 RJW72730.1 - 3.3 7.5 10.4 0.24 11.2 0.8 2.5 3 0 0 3 3 2 0 Spermatogenesis-associated protein 46 CpXC PF14353.6 RJW72730.1 - 6 6.9 12.9 13 5.9 0.0 4.0 2 2 1 3 3 3 0 CpXC protein zf-DNL PF05180.12 RJW72730.1 - 6.4 6.8 7.7 3.4 7.7 2.0 2.7 2 0 0 2 2 2 0 DNL zinc finger Peptidase_A17 PF05380.13 RJW72731.1 - 1.5e-54 184.3 0.0 4.1e-54 183.0 0.0 1.8 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF5641 PF18701.1 RJW72731.1 - 4.4e-28 97.3 2.9 1.1e-27 96.0 2.9 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 RJW72731.1 - 8.2e-08 32.3 2.4 2.2e-07 30.9 2.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1759 PF03564.15 RJW72731.1 - 3.1e-07 30.5 0.0 6.5e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Asp_protease_2 PF13650.6 RJW72731.1 - 0.00014 22.4 0.2 0.00042 20.9 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 RJW72731.1 - 0.0016 18.7 0.0 0.0045 17.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 RJW72731.1 - 0.0025 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 RJW72731.1 - 0.0066 17.0 0.0 0.02 15.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 RJW72731.1 - 0.041 13.7 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DNA_pol_viral_C PF00336.18 RJW72731.1 - 0.086 12.2 0.8 0.17 11.2 0.2 1.7 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain PDZ_6 PF17820.1 RJW72733.1 - 1.5e-09 37.6 0.7 2.1e-09 37.1 0.7 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW72733.1 - 2.9e-09 37.1 0.2 3.9e-09 36.7 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW72733.1 - 1.7e-05 25.0 0.0 2.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Glyco_transf_8 PF01501.20 RJW72734.1 - 2.4e-10 40.4 0.3 3.8e-10 39.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 RJW72734.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase NDK PF00334.19 RJW72735.1 - 5.5e-28 97.7 0.0 6.1e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF2396 PF09654.10 RJW72735.1 - 0.051 13.7 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) DUF2502 PF10697.9 RJW72735.1 - 0.072 13.5 0.7 0.17 12.2 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2502) GFRP PF06399.13 RJW72735.1 - 0.14 12.1 0.0 1.2 9.0 0.0 2.0 1 1 1 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Nup160 PF11715.8 RJW72737.1 - 0.013 14.2 0.1 0.031 12.9 0.1 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 NODP PF07684.12 RJW72737.1 - 0.098 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 NOTCH protein ELM2 PF01448.24 RJW72741.1 - 0.0011 19.6 0.1 0.0067 17.1 0.1 2.4 1 0 0 1 1 1 1 ELM2 domain DUF1296 PF06972.11 RJW72741.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) Glyco_transf_8 PF01501.20 RJW72742.1 - 5.2e-09 36.0 0.0 8.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ldl_recept_a PF00057.18 RJW72745.1 - 3.1e-17 62.5 23.3 5.6e-08 32.9 2.1 3.5 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A PLC-beta_C PF08703.10 RJW72745.1 - 0.055 13.5 0.5 0.095 12.7 0.5 1.3 1 0 0 1 1 1 0 PLC-beta C terminal ASC PF00858.24 RJW72746.1 - 1.3e-56 192.4 1.4 2.7e-56 191.4 1.4 1.5 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Pkinase PF00069.25 RJW72747.1 - 8.5e-46 156.4 0.0 1.1e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72747.1 - 2.3e-17 63.2 0.0 3.3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RJW72747.1 - 0.00038 19.9 0.1 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5352 PF17303.2 RJW72747.1 - 0.044 13.6 0.2 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5352) MutS_V PF00488.21 RJW72748.1 - 8.4e-36 123.8 0.3 1.5e-35 123.0 0.3 1.3 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.18 RJW72748.1 - 1.7e-07 31.5 0.0 3.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.18 RJW72748.1 - 2.2e-07 31.3 0.3 1.2e-06 28.8 0.1 1.9 2 0 0 2 2 2 1 MutS domain III SMC_N PF02463.19 RJW72748.1 - 0.059 12.8 1.4 4.3 6.7 0.1 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RJW72748.1 - 0.085 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 RJW72748.1 - 0.19 11.5 3.6 5.9 6.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase PF00069.25 RJW72749.1 - 2.5e-65 220.5 0.0 3.3e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72749.1 - 1.5e-46 158.8 0.0 2.1e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW72749.1 - 0.0014 17.5 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF1241 PF06840.11 RJW72749.1 - 0.0019 17.8 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Kinase-like PF14531.6 RJW72749.1 - 0.062 12.6 0.1 0.75 9.1 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Sec7 PF01369.20 RJW72750.1 - 8e-34 116.9 0.1 1.7e-33 115.8 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.10 RJW72750.1 - 1e-28 99.0 1.2 1.8e-27 95.0 0.2 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DUF1778 PF08681.11 RJW72750.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) Sec7 PF01369.20 RJW72751.1 - 1.4e-19 70.5 0.0 1.8e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain ARGLU PF15346.6 RJW72753.1 - 2.5e-13 50.2 27.9 4.2e-13 49.4 27.9 1.3 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 DUF445 PF04286.12 RJW72753.1 - 0.0069 16.2 4.4 0.0077 16.1 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) TP_methylase PF00590.20 RJW72753.1 - 0.016 15.1 1.4 0.023 14.7 1.1 1.4 1 1 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases LAMTOR PF15454.6 RJW72753.1 - 0.079 13.6 2.4 0.18 12.5 2.3 1.6 1 1 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Exonuc_VII_L PF02601.15 RJW72753.1 - 0.59 9.7 5.3 0.62 9.6 5.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF572 PF04502.13 RJW72753.1 - 0.77 9.3 9.8 0.76 9.3 9.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PRKCSH-like PF12999.7 RJW72753.1 - 2.6 7.8 4.9 3.9 7.3 4.9 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like FUSC PF04632.12 RJW72753.1 - 9.6 4.6 7.0 10 4.5 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CUB PF00431.20 RJW72754.1 - 4.2e-31 107.5 0.3 7.3e-10 39.2 0.0 5.1 5 0 0 5 5 5 5 CUB domain Branch PF02485.21 RJW72755.1 - 7.1e-30 104.3 0.0 1e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme PBD PF00786.28 RJW72757.1 - 1.2e-11 44.8 0.1 9.9e-11 41.8 0.0 2.6 3 0 0 3 3 3 1 P21-Rho-binding domain Pkinase PF00069.25 RJW72757.1 - 2.4e-08 33.7 0.0 3.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72757.1 - 0.00021 20.6 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AMP-binding PF00501.28 RJW72758.1 - 4.8e-44 150.6 0.0 6e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RJW72758.1 - 0.00038 21.4 0.1 0.00075 20.4 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sec7_N PF12783.7 RJW72761.1 - 1.2e-47 161.8 1.4 2.5e-47 160.7 1.4 1.6 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 RJW72761.1 - 2e-16 60.2 1.3 3.6e-16 59.3 1.3 1.3 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 AMP-binding PF00501.28 RJW72763.1 - 3.5e-60 203.8 0.0 4.3e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RJW72763.1 - 0.14 13.2 0.0 0.25 12.4 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Branch PF02485.21 RJW72764.1 - 1.2e-31 110.2 0.0 1.6e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme hSac2 PF12456.8 RJW72765.1 - 2.7e-17 62.5 0.0 4e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Inositol phosphatase RVT_1 PF00078.27 RJW72766.1 - 2.8e-46 157.8 0.6 9.5e-46 156.1 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW72766.1 - 1.5e-11 44.2 0.0 7.3e-11 42.0 0.0 2.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase DND1_DSRM PF14709.7 RJW72768.1 - 0.14 12.5 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dNK PF01712.19 RJW72770.1 - 1.8e-20 73.7 0.3 8.6e-20 71.5 0.0 2.1 2 1 0 2 2 2 1 Deoxynucleoside kinase AAA_28 PF13521.6 RJW72770.1 - 0.0021 18.4 0.0 0.24 11.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RJW72770.1 - 0.0031 17.7 0.0 0.0076 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RJW72770.1 - 0.016 15.8 0.0 0.095 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RJW72770.1 - 0.043 14.1 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RJW72770.1 - 0.052 13.9 0.0 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 RJW72770.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 RJW72770.1 - 0.055 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 RJW72770.1 - 0.056 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 RJW72770.1 - 0.18 12.2 0.0 4.1 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-C2H2 PF00096.26 RJW72771.1 - 1.1e-21 76.0 49.4 2.3e-05 24.6 5.0 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW72771.1 - 4e-15 55.2 47.4 0.0015 19.2 4.9 6.0 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW72771.1 - 2.4e-09 37.2 39.5 0.0041 17.5 0.5 7.1 7 1 0 7 7 7 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW72771.1 - 7.6e-09 35.6 17.4 0.036 14.4 0.2 5.6 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RJW72771.1 - 4.2e-08 33.3 14.4 0.0083 16.5 0.2 5.4 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RJW72771.1 - 4.3e-06 26.9 23.1 0.0059 16.9 3.8 3.6 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 RJW72771.1 - 3.6e-05 23.4 28.5 0.0094 15.7 0.4 5.9 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RJW72771.1 - 0.00015 21.7 24.7 0.0015 18.5 1.9 5.4 5 0 0 5 5 5 2 C2H2-type zinc finger Rad50_zn_hook PF04423.14 RJW72771.1 - 0.0032 17.3 4.6 2.2 8.2 0.1 3.3 3 0 0 3 3 3 2 Rad50 zinc hook motif zf-BED PF02892.15 RJW72771.1 - 0.0055 16.7 5.7 0.0055 16.7 5.7 3.9 4 0 0 4 4 4 2 BED zinc finger zf_C2H2_ZHX PF18387.1 RJW72771.1 - 0.0088 15.7 9.6 2.2 8.0 0.1 4.3 2 1 2 4 4 4 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 RJW72771.1 - 0.019 14.7 0.3 0.019 14.7 0.3 6.1 6 0 0 6 6 5 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 RJW72771.1 - 0.021 15.5 11.0 0.39 11.5 1.1 3.1 2 1 2 4 4 4 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 RJW72771.1 - 0.079 13.1 19.4 0.12 12.5 4.4 4.0 2 2 1 3 3 3 0 Zinc ribbon domain FOXP-CC PF16159.5 RJW72771.1 - 0.12 13.0 18.7 10 6.9 0.3 5.0 2 2 2 4 4 4 0 FOXP coiled-coil domain zf_UBZ PF18439.1 RJW72771.1 - 0.12 12.0 0.3 0.12 12.0 0.3 4.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 RJW72771.1 - 0.15 11.9 15.5 3.3 7.6 0.3 5.0 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 RJW72771.1 - 0.69 10.6 12.5 86 3.8 0.7 3.6 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats GATA PF00320.27 RJW72771.1 - 0.73 9.5 7.4 0.22 11.2 1.3 3.1 2 1 0 2 2 2 0 GATA zinc finger DUF1610 PF07754.11 RJW72771.1 - 0.97 9.5 11.1 0.5 10.4 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-C2H2_2 PF12756.7 RJW72771.1 - 1.4 9.3 19.7 0.82 10.0 4.7 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 RJW72771.1 - 3 8.2 9.5 8.5 6.7 0.5 4.0 4 0 0 4 4 4 0 zinc-ribbon Rubredoxin_2 PF18073.1 RJW72771.1 - 4.6 7.0 17.1 1.2 8.9 1.0 4.5 4 0 0 4 4 4 0 Rubredoxin metal binding domain Ogr_Delta PF04606.12 RJW72771.1 - 5.6 7.0 15.6 0.51 10.4 0.9 4.0 3 2 0 3 3 3 0 Ogr/Delta-like zinc finger zinc-ribbons_6 PF07191.12 RJW72771.1 - 5.8 7.0 13.4 14 5.7 6.4 3.2 2 1 0 2 2 2 0 zinc-ribbons KH_1 PF00013.29 RJW72773.1 - 4.5e-20 71.2 0.0 1.7e-08 34.1 0.1 4.9 5 0 0 5 5 5 3 KH domain KH_2 PF07650.17 RJW72773.1 - 3.5e-06 26.7 0.3 0.0039 17.0 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 RJW72773.1 - 0.031 14.1 0.4 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 KH domain KH_5 PF13184.6 RJW72773.1 - 0.04 14.0 0.1 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 NusA-like KH domain zf-C4 PF00105.18 RJW72774.1 - 7e-28 96.9 15.9 1.2e-27 96.1 15.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.5 RJW72774.1 - 0.27 11.4 5.6 0.73 10.0 5.6 1.7 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Kinesin PF00225.23 RJW72776.1 - 1.4e-45 155.7 0.1 1.4e-45 155.7 0.1 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RJW72776.1 - 1.7e-25 89.7 2.4 3e-25 88.9 0.0 2.5 3 1 0 3 3 3 1 Microtubule binding AAA_17 PF13207.6 RJW72776.1 - 0.065 13.7 0.6 0.7 10.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF4472 PF14739.6 RJW72776.1 - 0.59 10.9 17.4 3.6 8.4 6.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) APG6_N PF17675.1 RJW72776.1 - 6.8 7.2 33.3 9.8 6.7 9.7 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region zf-MIZ PF02891.20 RJW72777.1 - 5.9e-20 70.8 5.3 1.1e-19 69.9 5.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 RJW72777.1 - 0.00029 20.6 3.2 0.00078 19.2 3.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 RJW72777.1 - 1 9.7 5.7 2.2 8.7 5.7 1.6 1 0 0 1 1 1 0 Ring finger domain Collagen PF01391.18 RJW72778.1 - 0.00056 19.6 15.0 0.11 12.2 0.3 2.5 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) Endostatin PF06482.11 RJW72778.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Sigma70_ner PF04546.13 RJW72778.1 - 0.62 9.9 16.4 0.93 9.3 16.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 RJW72778.1 - 1.6 6.8 35.0 2.2 6.3 35.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-C2H2 PF00096.26 RJW72779.1 - 4.2e-27 93.0 38.1 1.4e-05 25.2 1.1 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW72779.1 - 8.5e-20 69.7 34.3 0.00053 20.6 1.7 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW72779.1 - 3.3e-13 49.4 38.5 0.0051 17.2 3.0 7.0 6 1 0 6 6 6 4 Zinc-finger double domain zf-Di19 PF05605.12 RJW72779.1 - 2.7e-09 37.2 19.6 0.00059 20.1 3.5 3.6 2 1 2 4 4 4 4 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RJW72779.1 - 3.9e-07 30.3 12.6 0.35 11.3 0.1 5.8 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 RJW72779.1 - 9.1e-07 28.6 1.2 9.1e-07 28.6 1.2 5.0 5 0 0 5 5 4 2 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 RJW72779.1 - 4.5e-06 26.7 14.5 0.00076 19.5 1.5 4.2 3 1 1 4 4 4 2 Zinc ribbon domain zf-C2H2_jaz PF12171.8 RJW72779.1 - 7.5e-06 26.1 19.1 0.16 12.3 0.2 5.7 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 RJW72779.1 - 3e-05 23.8 12.6 0.15 11.9 0.2 5.1 3 2 2 5 5 5 2 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 RJW72779.1 - 8.5e-05 22.1 17.4 0.19 11.4 0.1 5.2 6 0 0 6 6 4 3 Ubiquitin-Binding Zinc Finger Rad50_zn_hook PF04423.14 RJW72779.1 - 0.00027 20.7 7.7 0.81 9.6 0.1 3.6 3 0 0 3 3 3 2 Rad50 zinc hook motif TF_Zn_Ribbon PF08271.12 RJW72779.1 - 0.0003 20.2 10.9 0.01 15.4 0.3 4.1 4 0 0 4 4 4 1 TFIIB zinc-binding ADK_lid PF05191.14 RJW72779.1 - 0.00034 20.5 6.7 0.029 14.4 0.2 3.7 2 1 1 3 3 3 2 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 RJW72779.1 - 0.0004 20.1 23.0 0.36 10.6 0.0 5.2 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RJW72779.1 - 0.00056 19.8 23.9 0.067 13.2 0.1 5.8 5 1 0 5 5 5 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RJW72779.1 - 0.0013 18.3 13.1 0.062 13.0 0.0 4.5 1 1 3 4 4 4 2 Zinc-fingers and homeoboxes C2H2 finger domain CpXC PF14353.6 RJW72779.1 - 0.0047 17.0 13.0 4.8 7.2 0.7 4.6 1 1 3 4 4 4 0 CpXC protein DUF2321 PF10083.9 RJW72779.1 - 0.0074 15.9 5.9 0.38 10.4 0.3 2.7 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2321) zinc_ribbon_15 PF17032.5 RJW72779.1 - 0.014 16.1 15.3 0.017 15.8 0.5 3.5 3 1 2 5 5 4 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 RJW72779.1 - 0.021 14.8 11.6 0.086 12.8 3.4 3.4 2 2 0 2 2 2 0 zinc-ribbons DUF2310 PF10071.9 RJW72779.1 - 0.031 13.6 10.1 1.8 7.8 0.1 3.1 2 1 1 3 3 3 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) TFIIS_C PF01096.18 RJW72779.1 - 0.036 13.9 0.8 0.036 13.9 0.8 4.1 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) HypA PF01155.19 RJW72779.1 - 0.04 13.9 8.8 0.51 10.4 0.7 3.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GAGA PF09237.11 RJW72779.1 - 0.044 13.6 20.5 0.11 12.3 1.2 4.3 3 1 1 4 4 4 0 GAGA factor zf-C2H2_8 PF15909.5 RJW72779.1 - 0.057 13.7 10.7 0.18 12.2 1.6 2.6 1 1 0 2 2 2 0 C2H2-type zinc ribbon Ogr_Delta PF04606.12 RJW72779.1 - 0.067 13.2 0.3 0.067 13.2 0.3 3.8 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.7 RJW72779.1 - 0.078 13.0 21.8 3.8 7.6 0.6 4.0 2 1 2 4 4 4 0 Transposase zinc-ribbon domain zf-C2H2_2 PF12756.7 RJW72779.1 - 0.09 13.1 24.1 3.6 8.0 0.1 4.9 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF1610 PF07754.11 RJW72779.1 - 0.11 12.5 0.1 0.11 12.5 0.1 4.4 5 0 0 5 5 4 0 Domain of unknown function (DUF1610) zf-BED PF02892.15 RJW72779.1 - 0.12 12.4 28.3 1.4 9.0 6.5 5.3 2 2 3 5 5 5 0 BED zinc finger zf-C2H2_3rep PF18868.1 RJW72779.1 - 0.15 12.8 16.1 0.36 11.5 4.1 3.4 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats A2L_zn_ribbon PF08792.10 RJW72779.1 - 0.15 11.8 6.7 12 5.7 0.2 4.3 4 0 0 4 4 4 0 A2L zinc ribbon domain zinc_ribbon_9 PF14369.6 RJW72779.1 - 0.15 12.3 14.8 3.8 7.8 0.1 5.2 6 0 0 6 6 4 0 zinc-ribbon Zn-C2H2_12 PF18112.1 RJW72779.1 - 0.16 12.4 9.9 3.7 8.1 0.1 4.6 5 0 0 5 5 4 0 Autophagy receptor zinc finger-C2H2 domain IBB PF01749.20 RJW72779.1 - 0.2 12.1 3.1 0.23 11.9 0.0 2.6 3 0 0 3 3 2 0 Importin beta binding domain DZR PF12773.7 RJW72779.1 - 0.23 11.5 17.1 0.45 10.6 7.2 3.8 1 1 1 2 2 2 0 Double zinc ribbon zf-C4_Topoisom PF01396.19 RJW72779.1 - 0.24 11.2 9.3 7 6.5 0.2 4.3 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger zf-IS66 PF13005.7 RJW72779.1 - 0.24 11.8 6.8 5.4 7.5 0.1 4.1 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 OrfB_Zn_ribbon PF07282.11 RJW72779.1 - 0.35 10.8 15.3 0.54 10.2 0.8 3.9 2 1 1 3 3 3 0 Putative transposase DNA-binding domain DUF2256 PF10013.9 RJW72779.1 - 0.79 9.9 15.6 6.5 7.0 0.0 4.7 5 0 0 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2256) YhfH PF14149.6 RJW72779.1 - 0.79 9.7 11.1 8.6 6.4 0.4 4.3 4 0 0 4 4 4 0 YhfH-like protein zf-LYAR PF08790.11 RJW72779.1 - 0.9 9.5 6.7 16 5.5 0.0 3.8 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Zn_ribbon_recom PF13408.6 RJW72779.1 - 1.3 9.6 14.4 18 5.9 0.1 3.9 3 2 0 3 3 3 0 Recombinase zinc beta ribbon domain Nop10p PF04135.12 RJW72779.1 - 1.4 9.0 5.2 57 3.9 0.1 3.9 4 0 0 4 4 3 0 Nucleolar RNA-binding protein, Nop10p family zf-Mss51 PF13824.6 RJW72779.1 - 1.8 8.7 29.5 2.1 8.5 0.7 5.6 2 2 2 4 4 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_ribbon_SprT PF17283.2 RJW72779.1 - 2 8.4 20.6 0.94 9.4 1.2 3.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Sprouty PF05210.13 RJW72779.1 - 2 8.8 7.7 0.5 10.8 1.8 2.4 2 0 0 2 2 2 0 Sprouty protein (Spry) Vps36-NZF-N PF16988.5 RJW72779.1 - 2 7.9 0.0 2 7.9 0.0 4.2 4 2 1 5 5 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Prok-RING_1 PF14446.6 RJW72779.1 - 2.3 8.2 20.2 21 5.1 0.1 5.8 5 1 0 5 5 5 0 Prokaryotic RING finger family 1 DUF983 PF06170.12 RJW72779.1 - 2.4 8.6 6.5 1.1e+02 3.3 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF983) Sgf11 PF08209.11 RJW72779.1 - 2.5 7.8 17.4 22 4.7 0.1 5.6 6 0 0 6 6 5 0 Sgf11 (transcriptional regulation protein) FYDLN_acid PF09538.10 RJW72779.1 - 3.1 8.5 16.0 23 5.8 0.7 5.2 2 1 2 5 5 5 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_2 PF13240.6 RJW72779.1 - 5.1 7.0 20.1 7.7 6.4 0.1 4.7 5 0 0 5 5 4 0 zinc-ribbon domain CxC7 PF18866.1 RJW72779.1 - 5.3 7.3 6.2 26 5.1 0.0 3.5 3 1 1 4 4 3 0 CxC7 like cysteine cluster associated with KDZ transposases DNA_ligase_ZBD PF03119.16 RJW72779.1 - 7.2 6.7 12.0 12 6.0 0.1 3.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Peptidase_C2 PF00648.21 RJW72782.1 - 1.9e-37 128.9 0.0 2.5e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease zf-RING_4 PF14570.6 RJW72783.1 - 1.2e-18 66.6 13.4 2e-18 65.9 13.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 RJW72783.1 - 3.4e-05 23.6 8.3 8.1e-05 22.4 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW72783.1 - 0.00078 19.7 9.7 0.0018 18.6 9.7 1.6 1 0 0 1 1 1 1 Ring finger domain RRM_1 PF00076.22 RJW72783.1 - 0.0092 15.8 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.25 RJW72783.1 - 0.027 14.4 8.9 0.052 13.4 8.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RJW72783.1 - 0.033 14.0 9.9 0.065 13.1 9.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 RJW72783.1 - 0.035 14.2 3.5 0.082 13.0 3.5 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Torus PF16131.5 RJW72783.1 - 0.047 14.4 0.2 0.16 12.7 0.2 1.9 1 0 0 1 1 1 0 Torus domain FYVE_2 PF02318.16 RJW72783.1 - 0.22 11.7 3.4 0.45 10.7 3.4 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Baculo_IE-1 PF05290.11 RJW72783.1 - 0.26 11.2 5.2 0.5 10.3 5.2 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 RJW72783.1 - 0.36 10.9 3.1 0.77 9.9 3.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RJW72783.1 - 0.37 10.7 9.4 3.7 7.5 8.6 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RJW72783.1 - 4.2 7.4 7.8 8.4 6.5 7.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.25 RJW72784.1 - 1.2e-37 129.8 0.0 3e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72784.1 - 1.3e-31 109.9 0.0 2.5e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RJW72784.1 - 0.00012 22.1 4.6 0.0016 18.5 3.7 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RJW72784.1 - 0.00022 20.6 1.5 0.00042 19.7 0.4 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RJW72784.1 - 0.00046 19.1 0.0 0.00099 18.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW72784.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like HisKA_3 PF07730.13 RJW72784.1 - 1.7 9.2 7.4 3.8 8.1 0.4 3.4 3 0 0 3 3 3 0 Histidine kinase PHD PF00628.29 RJW72785.1 - 0.057 13.3 6.9 0.23 11.4 6.9 2.2 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 RJW72786.1 - 4.3e-37 125.5 22.9 3.2e-08 34.1 2.6 7.5 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW72786.1 - 2.9e-16 59.5 2.7 1.1e-05 25.7 0.3 5.7 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain TBCA PF02970.16 RJW72786.1 - 0.32 11.4 5.7 0.99 9.8 5.6 1.9 1 1 0 1 1 1 0 Tubulin binding cofactor A HOOK PF05622.12 RJW72786.1 - 2.3 6.2 15.2 5.7 5.0 15.2 1.5 1 1 0 1 1 1 0 HOOK protein GAS PF13851.6 RJW72786.1 - 2.8 7.2 16.7 2.1 7.6 12.3 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 RJW72786.1 - 4.2 7.5 14.6 0.17 12.0 8.5 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase zf-C4H2 PF10146.9 RJW72786.1 - 6.4 7.0 10.2 20 5.4 9.6 2.0 2 1 0 2 2 2 0 Zinc finger-containing protein Cep57_CLD_2 PF14197.6 RJW72786.1 - 8.4 6.6 21.4 7.5 6.7 5.5 3.6 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 SGS PF05002.15 RJW72787.1 - 2.6e-12 46.7 0.3 5.1e-12 45.7 0.3 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 RJW72787.1 - 1.3e-10 42.1 0.0 3e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 CS domain Cadherin PF00028.17 RJW72788.1 - 2.7e-65 216.9 4.3 8.4e-15 55.0 0.0 9.3 7 1 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RJW72788.1 - 4.6e-09 36.0 0.8 0.0021 17.8 0.0 4.3 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 RJW72788.1 - 0.18 11.8 8.5 38 4.3 0.0 5.9 7 0 0 7 7 7 0 Cadherin-like DRMBL PF07522.14 RJW72789.1 - 0.00083 19.5 0.0 0.0068 16.6 0.0 2.3 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 RJW72789.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain EF-hand_7 PF13499.6 RJW72792.1 - 5.6e-09 36.3 3.8 6.4e-09 36.2 0.3 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW72792.1 - 4.5e-08 32.4 3.4 0.00014 21.5 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RJW72792.1 - 0.0019 18.0 2.7 0.018 14.9 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW72792.1 - 0.0035 16.8 0.0 0.0035 16.8 0.0 3.5 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 RJW72792.1 - 0.047 14.0 0.1 5.5 7.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 RJW72792.1 - 1.1 8.8 0.0 1.1 8.8 0.0 3.5 4 0 0 4 4 4 0 EF hand Radical_SAM_N PF08497.10 RJW72793.1 - 0.2 10.9 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal TPR_12 PF13424.6 RJW72797.1 - 1.7e-13 50.6 8.9 9.2e-10 38.7 1.7 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RJW72797.1 - 1.6e-11 43.5 9.2 0.0001 22.0 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW72797.1 - 1.1e-09 37.6 8.6 0.00053 19.9 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW72797.1 - 8.5e-09 34.9 6.6 0.00021 21.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RJW72797.1 - 0.00016 21.4 7.5 0.24 11.5 0.1 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW72797.1 - 0.00034 21.2 0.1 1.3 9.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RJW72797.1 - 0.0005 20.2 4.7 0.13 12.4 0.2 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RJW72797.1 - 0.0081 15.8 3.6 0.86 9.3 0.1 3.4 4 0 0 4 4 4 2 TPR repeat TPR_10 PF13374.6 RJW72797.1 - 0.0088 15.9 0.2 0.0088 15.9 0.2 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RJW72797.1 - 0.018 15.6 2.2 0.028 14.9 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 RJW72797.1 - 0.03 14.4 3.0 0.43 10.7 0.2 3.2 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 RJW72797.1 - 0.034 15.0 9.7 3.8 8.6 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PilO PF04350.13 RJW72797.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilO TPR_6 PF13174.6 RJW72797.1 - 0.1 13.2 10.3 5.8 7.8 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Gln-synt_N_2 PF16952.5 RJW72799.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain RhoGEF PF00621.20 RJW72801.1 - 7.1e-26 91.6 0.7 1.5e-25 90.5 0.3 1.7 1 1 1 2 2 2 1 RhoGEF domain PH_13 PF16652.5 RJW72801.1 - 1.7e-06 28.0 0.0 4.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_5 PF15405.6 RJW72801.1 - 0.0071 16.4 1.2 0.014 15.5 0.2 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain UPF0122 PF04297.14 RJW72801.1 - 0.11 12.8 0.1 0.33 11.2 0.1 1.9 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like RecQ_Zn_bind PF16124.5 RJW72801.1 - 0.19 12.4 1.2 3.4 8.5 0.3 3.0 2 0 0 2 2 2 0 RecQ zinc-binding Citrate_synt PF00285.21 RJW72803.1 - 1.7e-102 343.2 0.0 2e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PAS_3 PF08447.12 RJW72803.1 - 0.02 15.2 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 PAS fold Pkinase PF00069.25 RJW72804.1 - 3e-57 194.0 0.0 3.6e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72804.1 - 1.7e-34 119.3 0.0 2.1e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RJW72804.1 - 1.5e-06 27.7 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 RJW72804.1 - 0.00043 19.9 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 RJW72804.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW72804.1 - 0.068 13.1 0.1 0.54 10.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.25 RJW72805.1 - 2.7e-15 56.4 0.1 5.2e-10 39.1 0.0 2.7 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RJW72805.1 - 9.9e-05 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UBN_AB PF14075.6 RJW72806.1 - 8.3e-49 166.2 0.0 1.9e-48 165.0 0.0 1.6 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 RJW72806.1 - 3e-17 62.3 0.7 5.3e-17 61.6 0.7 1.4 1 0 0 1 1 1 1 HPC2 and ubinuclein domain BslA PF17735.1 RJW72806.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Biofilm surface layer A TarH PF02203.15 RJW72806.1 - 1.3 8.9 5.4 0.24 11.3 1.2 1.9 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF2040 PF09745.9 RJW72807.1 - 5.5e-29 100.7 17.1 5.5e-29 100.7 17.1 2.3 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) RabGAP-TBC PF00566.18 RJW72810.1 - 9.1e-15 54.9 2.0 3.9e-14 52.8 1.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GIY-YIG PF01541.24 RJW72812.1 - 0.0017 18.6 0.2 0.0039 17.4 0.2 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain Cadherin PF00028.17 RJW72817.1 - 5.1e-60 199.9 0.2 1.7e-12 47.6 0.0 9.9 7 3 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RJW72817.1 - 1.1e-08 34.8 3.1 0.00012 21.8 0.1 4.9 6 0 0 6 6 6 2 Cadherin-like Cadherin_3 PF16184.5 RJW72817.1 - 9 6.3 6.6 35 4.4 0.1 4.4 5 0 0 5 5 5 0 Cadherin-like Arf PF00025.21 RJW72818.1 - 1.4e-28 99.5 0.0 1.6e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RJW72818.1 - 6.2e-05 22.5 0.0 8.1e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 RJW72818.1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Ras family GTP_EFTU PF00009.27 RJW72818.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 RJW72818.1 - 0.022 13.8 0.0 0.075 12.0 0.0 1.7 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RVT_1 PF00078.27 RJW72819.1 - 8.4e-06 25.5 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 RJW72820.1 - 2.6e-41 141.6 0.0 7.3e-41 140.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW72820.1 - 5.3e-07 29.5 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase MatE PF01554.18 RJW72821.1 - 6.3e-39 133.2 35.2 1.1e-20 73.9 11.9 2.7 3 0 0 3 3 3 2 MatE DUF5378 PF17349.2 RJW72821.1 - 0.019 14.3 1.7 0.035 13.4 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5378) Pkinase_Tyr PF07714.17 RJW72822.1 - 7.3e-97 323.7 0.0 1e-96 323.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RJW72822.1 - 2.1e-51 174.9 0.0 3e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RJW72822.1 - 1.4e-20 73.2 0.6 2.7e-20 72.2 0.6 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 RJW72822.1 - 8.8e-15 54.1 0.0 5e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 RJW72822.1 - 1.5e-10 40.7 0.2 4.2e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 RJW72822.1 - 7.4e-08 32.0 0.2 1.3e-06 27.9 0.0 2.6 1 1 1 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 RJW72822.1 - 0.0013 17.8 0.2 0.005 15.8 0.2 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RJW72822.1 - 0.01 15.7 0.0 0.15 12.0 0.0 2.4 2 1 0 3 3 3 0 Phosphotransferase enzyme family SH3_16 PF18348.1 RJW72822.1 - 0.02 14.7 0.0 0.063 13.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain SH3_3 PF08239.11 RJW72822.1 - 0.14 12.5 0.0 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain Ribosomal_S3_C PF00189.20 RJW72823.1 - 0.15 12.6 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain DUF1030 PF06270.11 RJW72823.1 - 1.8 8.4 9.0 91 2.9 0.5 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF1030) SRP14 PF02290.15 RJW72825.1 - 1.1e-14 54.5 0.1 1.3e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle 14kD protein SAVED PF18145.1 RJW72825.1 - 0.0026 17.6 0.0 0.003 17.4 0.0 1.0 1 0 0 1 1 1 1 SMODS-associated and fused to various effectors sensor domain WD40 PF00400.32 RJW72826.1 - 2.8e-08 34.3 3.4 0.0064 17.3 3.6 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW72826.1 - 0.0026 18.0 0.0 1.6 9.1 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 RJW72827.1 - 1.2e-47 157.8 22.4 8.9e-09 34.8 0.2 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 RJW72827.1 - 1.9e-34 115.0 15.2 6.9e-07 28.9 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 RJW72827.1 - 3.6e-27 92.3 14.7 1.4e-05 24.9 1.7 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 RJW72827.1 - 2.6e-25 87.8 7.5 1.8e-09 37.1 0.4 4.5 3 1 1 4 4 4 3 TPR repeat TPR_12 PF13424.6 RJW72827.1 - 8.3e-21 74.1 12.1 1.6e-08 34.7 0.1 5.2 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 RJW72827.1 - 4.2e-17 61.4 0.6 0.01 16.6 0.0 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 RJW72827.1 - 2.6e-16 59.8 5.3 6.3e-05 23.4 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat STI1 PF17830.1 RJW72827.1 - 4.8e-13 48.8 1.1 1.6e-12 47.2 1.1 2.0 1 0 0 1 1 1 1 STI1 domain TPR_16 PF13432.6 RJW72827.1 - 3.2e-11 43.7 1.1 0.0023 18.6 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 RJW72827.1 - 1.2e-09 38.2 0.4 0.0017 18.4 0.0 4.7 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RJW72827.1 - 1.6e-09 37.2 7.3 0.023 14.7 0.1 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 RJW72827.1 - 2.8e-09 37.0 9.2 0.11 13.2 0.3 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW72827.1 - 8.7e-09 35.2 16.0 0.0013 18.9 0.5 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat NARP1 PF12569.8 RJW72827.1 - 8.2e-08 31.6 9.4 9.2e-05 21.5 0.1 3.8 1 1 3 4 4 4 2 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 RJW72827.1 - 3.7e-07 30.1 9.9 0.36 11.0 0.0 5.7 4 2 2 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 RJW72827.1 - 2.6e-05 23.9 12.2 0.26 11.2 0.2 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW72827.1 - 3.9e-05 23.8 14.4 0.00081 19.6 2.3 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 RJW72827.1 - 0.00021 20.8 1.9 0.00032 20.2 0.2 2.1 3 0 0 3 3 3 1 MalT-like TPR region TPR_3 PF07720.12 RJW72827.1 - 0.0011 18.9 5.8 1.5 8.9 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF627 PF04781.12 RJW72827.1 - 0.0032 17.5 4.7 0.58 10.2 0.0 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF627) TPR_21 PF09976.9 RJW72827.1 - 0.0093 15.7 9.5 0.91 9.2 0.2 3.9 2 1 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 RJW72827.1 - 0.013 14.8 1.5 0.96 8.6 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 RJW72827.1 - 0.069 13.2 12.9 0.36 10.9 0.1 4.8 4 2 0 4 4 4 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 RJW72827.1 - 0.083 11.9 0.1 0.2 10.6 0.1 1.6 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Peptidase_C2 PF00648.21 RJW72827.1 - 0.14 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Calpain family cysteine protease ATP-synt_D PF01813.17 RJW72827.1 - 0.14 12.0 3.6 0.59 9.9 2.6 2.2 2 1 0 2 2 2 0 ATP synthase subunit D YfiO PF13525.6 RJW72827.1 - 0.16 11.7 4.8 0.45 10.2 0.2 2.6 1 1 1 2 2 2 0 Outer membrane lipoprotein RPN7 PF10602.9 RJW72827.1 - 0.17 11.5 12.4 2.2 8.0 0.3 4.1 1 1 3 4 4 4 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 RJW72827.1 - 0.17 11.3 2.1 44 3.6 0.0 4.2 4 0 0 4 4 4 0 SHNi-TPR SNAP PF14938.6 RJW72827.1 - 0.25 10.7 18.3 13 5.1 8.6 3.7 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP CCDC-167 PF15188.6 RJW72827.1 - 0.32 11.4 3.8 0.59 10.5 0.8 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Alkyl_sulf_dimr PF14863.6 RJW72827.1 - 0.34 11.4 6.9 1.5 9.3 0.4 3.6 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation TssO PF17561.2 RJW72827.1 - 0.88 9.7 5.2 3.7 7.7 0.1 2.5 1 1 1 2 2 2 0 Type VI secretion system, TssO EF-hand_1 PF00036.32 RJW72830.1 - 1.1e-23 80.9 7.4 3e-07 29.5 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW72830.1 - 7e-19 68.1 1.0 5.9e-11 42.7 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW72830.1 - 2e-18 65.0 4.4 1.5e-05 24.3 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RJW72830.1 - 3.5e-16 57.7 3.9 4.3e-05 23.1 0.1 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RJW72830.1 - 1.7e-12 47.0 6.6 6.3e-07 29.1 0.2 4.3 2 1 1 3 3 3 3 EF-hand domain pair RVT_1 PF00078.27 RJW72830.1 - 4.6e-07 29.6 0.0 6.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SPARC_Ca_bdg PF10591.9 RJW72830.1 - 8.5e-05 22.8 0.1 0.13 12.6 0.0 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 RJW72830.1 - 0.19 12.0 0.0 32 4.8 0.0 2.6 2 0 0 2 2 2 0 Dockerin type I domain Pkinase_Tyr PF07714.17 RJW72831.1 - 2.3e-79 266.3 0.0 9.6e-41 139.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RJW72831.1 - 4e-39 134.6 0.0 9.8e-27 94.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SH2 PF00017.24 RJW72831.1 - 3.3e-12 46.3 0.0 9.2e-11 41.7 0.0 2.8 1 1 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 RJW72831.1 - 2.9e-08 33.2 0.0 7.2e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RJW72831.1 - 4.9e-06 26.3 0.0 2.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Pkinase_fungal PF17667.1 RJW72831.1 - 0.00052 18.9 0.0 0.00083 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SH3_2 PF07653.17 RJW72831.1 - 0.0055 16.4 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.6 RJW72831.1 - 0.017 14.4 0.0 4.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Kinase-like CTK3_C PF12350.8 RJW72831.1 - 0.023 14.8 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus APH PF01636.23 RJW72831.1 - 0.064 13.2 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family TED_complement PF07678.14 RJW72832.1 - 9.3e-27 93.9 0.0 1.6e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 RJW72832.1 - 9.3e-18 64.7 0.3 2.4e-17 63.4 0.3 1.8 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain A2M_BRD PF07703.14 RJW72832.1 - 6.8e-14 52.4 0.5 1.7e-13 51.1 0.5 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 RJW72832.1 - 1.9e-07 30.8 0.0 4.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Alpha-2-macroglobulin family Ldl_recept_a PF00057.18 RJW72832.1 - 0.029 14.6 3.3 0.058 13.6 3.3 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Tom37 PF10568.9 RJW72832.1 - 0.071 13.4 0.1 3.4 8.0 0.1 2.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Spore-coat_CotD PF11122.8 RJW72832.1 - 0.1 13.4 0.6 0.29 12.0 0.6 1.7 1 0 0 1 1 1 0 Inner spore coat protein D KH_8 PF17903.1 RJW72833.1 - 1.4e-31 108.4 0.1 3.1e-31 107.3 0.1 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 RJW72833.1 - 0.0081 16.0 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 RJW72833.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 KH domain PLAC8 PF04749.17 RJW72834.1 - 0.00081 20.4 8.1 0.0015 19.5 8.1 1.4 1 1 0 1 1 1 1 PLAC8 family DAGK_cat PF00781.24 RJW72835.1 - 4.2e-20 71.6 0.0 7.1e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CENP-O PF09496.10 RJW72835.1 - 0.18 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Asp PF00026.23 RJW72836.1 - 6.6e-18 65.2 0.0 7.3e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RJW72836.1 - 0.0055 16.5 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal LRRFIP PF09738.9 RJW72838.1 - 0.00066 19.3 14.2 0.00098 18.7 14.2 1.3 1 1 0 1 1 1 1 LRRFIP family Atg14 PF10186.9 RJW72838.1 - 0.0045 16.1 11.7 0.0056 15.8 11.7 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Mod_r PF07200.13 RJW72838.1 - 0.008 16.3 13.5 0.015 15.4 13.5 1.5 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF1796 PF08795.10 RJW72838.1 - 0.34 10.9 3.1 0.33 10.9 1.2 1.8 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) OSCP PF00213.18 RJW72838.1 - 0.72 10.0 6.2 11 6.2 0.1 2.1 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit zf-C4H2 PF10146.9 RJW72838.1 - 1.2 9.3 10.1 1.6 9.0 10.1 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein TMPIT PF07851.13 RJW72838.1 - 2.5 7.3 7.5 2.9 7.0 7.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 RJW72838.1 - 4.9 7.4 7.8 1.7 8.9 4.0 2.2 2 1 0 2 2 2 0 Haemolysin XhlA FapA PF03961.13 RJW72838.1 - 5 5.6 9.1 5.9 5.4 9.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 RJW72838.1 - 7 7.3 13.8 1.3 9.7 2.5 2.6 1 1 2 3 3 3 0 Initiation control protein YabA AAA_23 PF13476.6 RJW72838.1 - 9.2 6.7 18.8 11 6.4 18.8 1.1 1 0 0 1 1 1 0 AAA domain RTC PF01137.21 RJW72839.1 - 4.9e-75 251.5 0.0 6.4e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 RJW72839.1 - 0.00032 21.2 0.0 0.00091 19.7 0.0 1.8 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain SRP68 PF16969.5 RJW72840.1 - 2.3e-150 502.3 3.5 2.7e-150 502.1 3.5 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 BRO1 PF03097.18 RJW72840.1 - 0.036 12.9 2.6 0.35 9.6 0.1 2.9 3 0 0 3 3 3 0 BRO1-like domain MFS_1 PF07690.16 RJW72842.1 - 5.1e-15 55.2 42.0 9.5e-11 41.2 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily C2 PF00168.30 RJW72843.1 - 5.3e-09 36.3 0.1 0.00024 21.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain zf-C3HC4_3 PF13920.6 RJW72845.1 - 1.7e-11 43.8 11.8 4.7e-11 42.4 11.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FERM_N PF09379.10 RJW72845.1 - 0.00074 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain Prok-RING_4 PF14447.6 RJW72845.1 - 0.14 12.0 15.9 0.35 10.8 15.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RJW72845.1 - 0.22 11.5 11.8 0.65 10.0 11.8 1.9 1 0 0 1 1 1 0 zinc-RING finger domain MFS_1 PF07690.16 RJW72846.1 - 1.9e-26 92.8 35.9 3.6e-19 68.9 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily stn_TNFRSF12A PF12191.8 RJW72847.1 - 0.019 15.2 0.2 0.074 13.3 0.0 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain ABC2_membrane_2 PF12679.7 RJW72847.1 - 0.054 12.8 1.3 0.087 12.1 1.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Patched PF02460.18 RJW72847.1 - 0.15 10.1 0.3 0.2 9.7 0.3 1.1 1 0 0 1 1 1 0 Patched family DHHC PF01529.20 RJW72848.1 - 8.5e-38 129.5 10.2 8.5e-38 129.5 10.2 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase O-ag_pol_Wzy PF14296.6 RJW72848.1 - 0.0014 17.4 0.7 0.0014 17.4 0.7 1.8 2 0 0 2 2 2 1 O-antigen polysaccharide polymerase Wzy Frag1 PF10277.9 RJW72848.1 - 0.0022 17.6 1.3 0.0022 17.6 1.3 1.8 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Renin_r PF07850.14 RJW72848.1 - 0.02 15.5 4.4 0.11 13.1 0.0 3.1 2 1 0 2 2 2 0 Renin receptor-like protein DUF898 PF05987.13 RJW72848.1 - 1.5 7.8 6.5 0.16 11.0 0.2 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) ACR_tran PF00873.19 RJW72849.1 - 0.038 11.6 0.0 0.046 11.4 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family AAA_lid_4 PF17864.1 RJW72849.1 - 0.065 13.0 0.4 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 RuvB AAA lid domain Lysine_decarbox PF03641.14 RJW72849.1 - 0.19 11.8 0.0 0.9 9.6 0.0 1.9 2 0 0 2 2 2 0 Possible lysine decarboxylase WD40 PF00400.32 RJW72850.1 - 8.2e-12 45.5 3.2 0.095 13.6 0.3 5.3 4 0 0 4 4 4 4 WD domain, G-beta repeat TPR_16 PF13432.6 RJW72850.1 - 0.033 14.8 0.2 0.092 13.4 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat C2 PF00168.30 RJW72851.1 - 9.2e-10 38.7 0.0 2.8e-08 34.0 0.0 3.0 2 1 0 2 2 2 1 C2 domain Membr_traf_MHD PF10540.9 RJW72851.1 - 1.7e-05 25.0 0.9 0.00026 21.2 0.9 2.5 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain Phage_connect_1 PF05135.13 RJW72851.1 - 0.011 16.2 0.0 18 5.9 0.0 4.4 5 0 0 5 5 5 0 Phage gp6-like head-tail connector protein DUF4455 PF14643.6 RJW72852.1 - 9.2e-128 426.8 19.7 9.2e-128 426.8 19.7 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4455) Sec3_C_2 PF15278.6 RJW72852.1 - 0.05 14.0 0.1 0.43 10.9 0.0 2.8 2 0 0 2 2 2 0 Sec3 exocyst complex subunit HLH PF00010.26 RJW72852.1 - 0.067 13.2 4.5 2.8 8.0 0.1 4.1 4 1 0 4 4 4 0 Helix-loop-helix DNA-binding domain LigT_PEase PF02834.16 RJW72852.1 - 0.09 13.0 0.1 0.52 10.5 0.1 2.3 1 0 0 1 1 1 0 LigT like Phosphoesterase Mst1_SARAH PF11629.8 RJW72852.1 - 0.62 10.2 3.0 1.3 9.2 0.4 3.1 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF948 PF06103.11 RJW72852.1 - 1.4 9.2 7.2 4.3 7.7 0.0 4.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ntox28 PF15605.6 RJW72852.1 - 2.3 8.5 7.5 0.29 11.4 1.3 2.8 2 1 0 2 2 2 0 Bacterial toxin 28 ACP_PD PF04336.12 RJW72852.1 - 4.4 7.8 13.2 11 6.5 0.2 5.1 6 0 0 6 6 6 0 Acyl carrier protein phosphodiesterase NPV_P10 PF05531.12 RJW72852.1 - 5.7 7.5 11.4 6.6 7.3 0.2 4.5 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Laminin_G_2 PF02210.24 RJW72853.1 - 0.0097 16.5 0.0 0.029 14.9 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain Ig_3 PF13927.6 RJW72855.1 - 7.3e-26 90.6 0.0 1.2e-10 41.8 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RJW72855.1 - 3.9e-21 74.9 0.0 8.2e-08 32.2 0.0 4.5 3 2 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 RJW72855.1 - 1.3e-16 60.5 0.4 3.1e-05 24.1 0.0 4.3 4 2 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 RJW72855.1 - 1.3e-16 60.7 0.1 0.00011 22.3 0.1 3.7 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.6 RJW72855.1 - 1.5e-10 41.3 1.4 0.012 15.9 0.3 4.8 4 1 0 4 4 4 2 Immunoglobulin domain Ig_6 PF18452.1 RJW72855.1 - 0.00027 20.4 0.1 0.074 12.6 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 RJW72855.1 - 0.00031 20.7 0.0 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 RJW72855.1 - 0.0017 18.4 0.1 2 8.5 0.0 2.8 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 RJW72855.1 - 0.025 14.6 0.0 0.75 9.8 0.1 2.4 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Pro_isomerase PF00160.21 RJW72856.1 - 2.5e-37 128.6 0.0 4.4e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PHO4 PF01384.20 RJW72857.1 - 0.11 11.6 3.6 0.095 11.7 3.6 1.1 1 0 0 1 1 1 0 Phosphate transporter family DUF4191 PF13829.6 RJW72857.1 - 6.4 6.1 21.1 9.6 5.5 21.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) RNA_pol_Rbc25 PF08292.12 RJW72858.1 - 2.2e-29 102.3 0.0 3.3e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 RJW72858.1 - 1.2e-14 54.5 0.1 2.1e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 RJW72858.1 - 0.00049 20.4 0.0 0.00083 19.7 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Membr_traf_MHD PF10540.9 RJW72859.1 - 9.9e-45 152.3 1.0 1.4e-42 145.3 0.2 2.5 2 0 0 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 RJW72859.1 - 5e-39 132.8 0.2 1e-24 86.8 0.2 2.7 2 0 0 2 2 2 2 C2 domain DUF1041 PF06292.17 RJW72859.1 - 3.8e-31 107.6 0.2 1.6e-30 105.6 0.1 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) HSCB_C PF07743.13 RJW72859.1 - 0.046 14.2 0.2 2.3 8.7 0.1 3.0 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF4795 PF16043.5 RJW72859.1 - 0.055 13.1 0.6 0.12 11.9 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) CEP76-C2 PF15627.6 RJW72859.1 - 0.078 12.5 0.0 8.3 5.9 0.0 2.9 3 0 0 3 3 3 0 CEP76 C2 domain 7tm_1 PF00001.21 RJW72860.1 - 9.8e-09 34.9 0.3 1.6e-08 34.2 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DSPc PF00782.20 RJW72861.1 - 6.9e-07 29.1 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RJW72861.1 - 0.00049 19.7 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RJW72861.1 - 0.0021 18.2 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate TRIC PF05197.13 RJW72863.1 - 4.5e-75 251.5 2.3 5.8e-75 251.1 2.3 1.1 1 0 0 1 1 1 1 TRIC channel GpcrRhopsn4 PF10192.9 RJW72864.1 - 2.7e-24 86.0 15.9 4.2e-24 85.4 15.9 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 RJW72864.1 - 0.013 14.8 11.5 0.019 14.2 10.9 1.6 1 1 0 1 1 1 0 Lung seven transmembrane receptor SabA_adhesion PF18304.1 RJW72864.1 - 0.059 12.6 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain Ras PF00071.22 RJW72865.1 - 3e-48 163.5 0.0 3.6e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW72865.1 - 2.9e-28 98.5 0.0 4.3e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW72865.1 - 5.9e-09 35.6 0.0 9.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW72865.1 - 0.0026 17.8 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RJW72865.1 - 0.0045 16.5 0.0 0.48 9.9 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 RJW72865.1 - 0.019 14.5 0.0 0.058 12.9 0.0 1.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RJW72865.1 - 0.16 11.3 0.0 0.45 9.8 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF4113 PF13438.6 RJW72867.1 - 0.18 11.9 0.2 0.34 11.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) tRNA-synt_1 PF00133.22 RJW72870.1 - 6.3e-195 648.9 0.0 6.3e-194 645.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RJW72870.1 - 1.2e-35 122.8 1.9 1.5e-35 122.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RJW72870.1 - 2.1e-12 46.5 0.4 6.5e-05 21.9 0.0 3.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 RJW72870.1 - 1.2e-06 28.2 5.2 2.2e-06 27.3 0.0 3.1 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 Jag_N PF14804.6 RJW72870.1 - 0.00048 20.4 0.0 0.075 13.4 0.0 2.5 2 0 0 2 2 2 1 Jag N-terminus tRNA-synt_1e PF01406.19 RJW72870.1 - 0.049 13.0 0.0 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain NADHdh-2_N PF12155.8 RJW72871.1 - 0.18 12.2 0.4 0.39 11.1 0.4 1.4 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal Tmemb_55A PF09788.9 RJW72874.1 - 2.3e-37 128.4 2.8 2.7e-37 128.2 2.8 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A HypA PF01155.19 RJW72874.1 - 0.0057 16.7 4.1 0.089 12.8 0.0 2.6 2 1 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mu-like_Com PF10122.9 RJW72874.1 - 0.033 13.6 0.2 0.033 13.6 0.2 2.7 2 1 1 3 3 3 0 Mu-like prophage protein Com Zn-ribbon_8 PF09723.10 RJW72874.1 - 0.034 14.2 10.4 0.073 13.2 0.3 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Cys_rich_CPXG PF14255.6 RJW72874.1 - 0.16 11.9 1.7 21 5.1 0.0 3.1 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-FCS PF06467.14 RJW72874.1 - 0.69 9.9 5.7 8.1 6.5 0.0 4.1 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif IBR PF01485.21 RJW72874.1 - 1.2 9.5 9.2 1.3 9.3 2.9 3.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain AAA_6 PF12774.7 RJW72876.1 - 9.3e-145 481.7 0.0 8.2e-143 475.3 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW72876.1 - 1.8e-125 419.2 5.4 1.8e-125 419.2 5.4 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RJW72876.1 - 9.8e-93 310.2 0.0 1.9e-92 309.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RJW72876.1 - 1e-89 300.8 0.1 5.2e-89 298.5 0.0 2.3 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RJW72876.1 - 2.6e-83 278.5 1.1 1.8e-82 275.7 0.7 2.8 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 RJW72876.1 - 4.9e-72 241.2 0.4 6e-67 224.7 0.0 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RJW72876.1 - 1e-51 175.0 0.1 2.3e-51 173.9 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RJW72876.1 - 1.5e-42 145.9 6.5 2.6e-42 145.1 6.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RJW72876.1 - 3.8e-35 120.5 0.2 1.1e-21 77.2 0.0 4.2 5 0 0 5 5 3 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RJW72876.1 - 7.5e-25 87.5 0.0 7e-08 32.6 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RJW72876.1 - 1.1e-20 74.0 0.1 3.5e-20 72.4 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RJW72876.1 - 2.3e-15 56.6 3.1 3.6e-15 56.0 0.1 3.0 3 0 0 3 3 2 1 AAA+ lid domain AAA_22 PF13401.6 RJW72876.1 - 4.7e-08 33.4 0.5 0.012 15.9 0.0 5.3 5 0 0 5 5 4 1 AAA domain AAA_16 PF13191.6 RJW72876.1 - 3.5e-06 27.5 0.0 0.58 10.5 0.0 5.2 4 0 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 RJW72876.1 - 7.9e-06 26.3 0.1 1.2 9.6 0.0 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 RJW72876.1 - 0.0058 16.8 0.0 0.64 10.3 0.0 3.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase HemX PF04375.14 RJW72876.1 - 0.0075 15.6 10.1 0.0062 15.9 5.6 2.5 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase RsgA_GTPase PF03193.16 RJW72876.1 - 0.019 14.9 0.9 2.9 7.8 0.0 3.7 4 0 0 4 4 3 0 RsgA GTPase AAA_29 PF13555.6 RJW72876.1 - 0.024 14.4 0.3 16 5.3 0.0 3.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_19 PF13245.6 RJW72876.1 - 0.041 14.2 1.5 7.1 6.9 0.0 3.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 RJW72876.1 - 0.12 12.8 0.1 21 5.6 0.0 3.6 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 RJW72876.1 - 0.32 11.5 2.3 6.4 7.3 0.0 3.6 4 0 0 4 4 2 0 ABC transporter DUF3584 PF12128.8 RJW72876.1 - 1.4 6.4 11.8 0.46 7.9 3.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Flagellin_C PF00700.21 RJW72876.1 - 2.4 8.6 7.6 0.37 11.2 2.8 2.2 2 0 0 2 2 1 0 Bacterial flagellin C-terminal helical region HlyE PF06109.13 RJW72876.1 - 3 7.1 6.6 1.3 8.2 0.6 2.8 3 0 0 3 3 3 0 Haemolysin E (HlyE) DUF5082 PF16888.5 RJW72876.1 - 5.6 7.3 10.0 1.6 9.0 5.6 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) Laminin_I PF06008.14 RJW72876.1 - 6.8 6.3 22.1 0.77 9.4 1.1 3.3 3 1 0 3 3 3 0 Laminin Domain I PDZ_6 PF17820.1 RJW72877.1 - 5.3e-08 32.6 0.2 1.1e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW72877.1 - 8.1e-08 32.5 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RJW72877.1 - 0.00031 21.0 0.0 0.0007 19.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PEPCK_GTP PF00821.18 RJW72878.1 - 9e-159 528.1 0.0 1.1e-158 527.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 RJW72878.1 - 4.7e-91 304.3 0.0 6.8e-91 303.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Hid1 PF12722.7 RJW72879.1 - 3.4e-234 779.7 0.0 8.7e-232 771.7 0.0 2.0 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 RJW72879.1 - 1.3e-218 727.5 0.1 1.6e-218 727.2 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein MIG-14_Wnt-bd PF06664.12 RJW72880.1 - 1.5e-77 260.7 30.2 1.5e-77 260.7 30.2 1.4 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Abhydrolase_9_N PF15420.6 RJW72880.1 - 0.27 11.2 7.8 0.57 10.1 7.8 1.6 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus MPC PF03650.13 RJW72882.1 - 2.7e-13 50.0 0.0 2.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers PhaG_MnhG_YufB PF03334.14 RJW72882.1 - 0.037 14.3 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter subunit DUF5389 PF17364.2 RJW72882.1 - 0.056 13.5 0.1 0.066 13.3 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5389) PUL PF08324.11 RJW72882.1 - 0.22 10.8 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 PUL domain Adaptin_N PF01602.20 RJW72884.1 - 6e-141 470.6 4.8 2.3e-140 468.6 5.9 1.4 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 RJW72884.1 - 1.1e-17 64.5 4.9 3.8e-16 59.5 0.4 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RJW72884.1 - 1.7e-08 34.7 3.8 7.1e-05 23.1 0.3 4.5 3 2 1 4 4 4 1 HEAT repeats HEAT PF02985.22 RJW72884.1 - 8.3e-08 31.9 0.7 0.31 11.4 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat AP3B1_C PF14796.6 RJW72884.1 - 5.8e-07 29.9 0.0 3.4e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_EZ PF13513.6 RJW72884.1 - 0.77 10.3 3.1 4.5 7.9 0.1 3.9 4 1 1 5 5 5 0 HEAT-like repeat zf-H2C2_2 PF13465.6 RJW72885.1 - 5.2e-12 45.6 30.4 4e-09 36.5 1.1 5.5 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 RJW72885.1 - 0.00019 21.7 15.4 0.0025 18.2 2.4 5.7 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW72885.1 - 0.0049 17.6 13.8 0.024 15.5 1.2 5.8 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW72885.1 - 0.0086 15.8 2.4 0.0086 15.8 2.4 4.2 5 0 0 5 5 5 1 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 RJW72885.1 - 0.01 16.5 15.5 0.7 10.6 0.5 4.1 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 RJW72885.1 - 0.02 15.0 0.5 0.02 15.0 0.5 5.0 5 2 0 5 5 5 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 RJW72885.1 - 6.3 6.4 11.8 9.6 5.8 3.1 3.6 3 1 0 3 3 3 0 TFIIB zinc-binding DZR PF12773.7 RJW72885.1 - 7.5 6.7 22.6 6.7 6.8 7.7 4.2 2 1 1 3 3 3 0 Double zinc ribbon Rubredoxin_2 PF18073.1 RJW72885.1 - 10 6.0 16.6 1.4 8.7 0.2 4.5 4 0 0 4 4 4 0 Rubredoxin metal binding domain EF-hand_1 PF00036.32 RJW72886.1 - 3.3e-31 104.5 9.9 1.1e-07 30.9 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW72886.1 - 3.8e-29 100.9 4.0 3e-16 59.6 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW72886.1 - 2.4e-24 83.7 7.3 1.2e-05 24.6 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 RJW72886.1 - 4.7e-23 80.8 12.7 1.3e-12 47.3 2.5 4.4 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 RJW72886.1 - 2.1e-22 77.1 10.9 2.1e-06 27.2 0.1 5.4 5 2 1 6 6 6 4 EF-hand domain SPARC_Ca_bdg PF10591.9 RJW72886.1 - 5.6e-09 36.3 0.3 0.0027 18.0 0.0 2.3 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW72886.1 - 3.1e-07 30.3 1.1 0.036 14.0 0.0 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RJW72886.1 - 5e-06 26.6 4.5 0.011 16.0 0.2 3.6 2 2 2 4 4 4 2 Dockerin type I domain EF-hand_9 PF14658.6 RJW72886.1 - 0.00064 20.0 0.2 0.075 13.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 RJW72886.1 - 0.0018 18.2 0.5 0.095 12.6 0.0 2.7 2 2 0 2 2 2 1 Caleosin related protein TerB PF05099.13 RJW72886.1 - 0.0042 17.1 0.0 0.93 9.4 0.0 2.2 2 0 0 2 2 2 1 Tellurite resistance protein TerB YbjN PF10722.9 RJW72886.1 - 0.024 14.7 0.3 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator DUF4953 PF16313.5 RJW72886.1 - 0.032 13.5 0.0 0.13 11.5 0.0 1.7 1 1 1 2 2 2 0 Met-zincin SurA_N_2 PF13623.6 RJW72886.1 - 0.13 12.1 0.0 15 5.5 0.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain VCBS PF13517.6 RJW72886.1 - 7.8 7.2 13.3 1 10.0 1.0 3.5 2 2 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella F-box-like PF12937.7 RJW72890.1 - 5.6e-11 42.2 3.1 8.3e-11 41.6 0.4 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RJW72890.1 - 0.00023 20.9 0.2 0.00023 20.9 0.2 2.5 3 0 0 3 3 3 1 F-box domain F-box_5 PF18511.1 RJW72890.1 - 0.0059 16.1 0.1 0.013 15.0 0.1 1.6 1 0 0 1 1 1 1 F-box RPN13_C PF16550.5 RJW72890.1 - 0.044 14.0 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 UCH-binding domain EF-hand_1 PF00036.32 RJW72892.1 - 2.5e-30 101.7 11.1 1.5e-07 30.4 0.9 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW72892.1 - 2.9e-29 101.3 3.3 7.1e-16 58.4 1.8 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW72892.1 - 5.3e-24 82.6 6.6 2.3e-05 23.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RJW72892.1 - 1.5e-21 74.4 11.9 3.3e-06 26.6 0.1 5.1 5 1 1 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 RJW72892.1 - 2.5e-19 68.9 12.1 4.1e-12 45.7 2.7 3.7 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW72892.1 - 1.1e-08 35.3 0.3 0.0026 18.1 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW72892.1 - 8.9e-06 25.6 2.2 0.055 13.4 0.1 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RJW72892.1 - 3e-05 24.1 4.5 0.022 14.9 0.2 3.5 2 2 1 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 RJW72892.1 - 0.029 14.3 0.5 0.73 9.7 0.0 2.7 2 1 0 2 2 2 0 Caleosin related protein TerB PF05099.13 RJW72892.1 - 0.15 12.1 0.0 20 5.1 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB Tetraspanin PF00335.20 RJW72893.1 - 3.7e-18 66.1 14.2 5.6e-18 65.5 14.2 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF3139 PF11337.8 RJW72893.1 - 0.035 14.7 0.1 0.035 14.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) PDEase_I PF00233.19 RJW72894.1 - 7.6e-70 235.3 0.2 1.1e-69 234.8 0.2 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SWIRM-assoc_2 PF16496.5 RJW72894.1 - 0.044 12.7 0.1 0.079 11.8 0.1 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Dynein_IC2 PF11540.8 RJW72895.1 - 2.6e-12 46.4 0.6 5.4e-12 45.4 0.6 1.5 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 RJW72895.1 - 4.3e-10 40.0 11.7 0.018 15.9 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat WD40_like PF17005.5 RJW72895.1 - 0.079 12.3 0.0 2.7 7.2 0.0 2.4 1 1 1 2 2 2 0 WD40-like domain RRM_1 PF00076.22 RJW72897.1 - 1.5e-17 63.1 0.3 2.8e-17 62.3 0.3 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW72897.1 - 0.00013 22.0 0.1 0.00049 20.2 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 RJW72897.1 - 0.029 14.4 0.1 0.059 13.4 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif IPK PF03770.16 RJW72899.1 - 5.3e-23 81.9 0.0 7.8e-23 81.4 0.0 1.3 1 1 0 1 1 1 1 Inositol polyphosphate kinase Tubulin PF00091.25 RJW72901.1 - 1.9e-48 165.3 0.0 3.4e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW72901.1 - 3.4e-22 78.9 0.0 7.6e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW72901.1 - 0.0014 18.4 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain zf-LITAF-like PF10601.9 RJW72902.1 - 2.5e-17 62.9 7.1 5.3e-17 61.8 7.1 1.6 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-dskA_traR PF01258.17 RJW72902.1 - 0.0041 17.0 0.5 0.32 11.0 0.0 2.4 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger zinc_ribbon_2 PF13240.6 RJW72902.1 - 0.019 14.6 6.5 0.072 12.8 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 RJW72902.1 - 0.037 14.2 2.3 2.9 8.1 0.8 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 RJW72902.1 - 0.043 13.2 1.0 3.2 7.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 RJW72902.1 - 0.072 13.0 3.0 13 5.7 0.1 3.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DZR PF12773.7 RJW72902.1 - 0.19 11.8 3.8 2.1 8.5 3.9 2.3 1 1 0 1 1 1 0 Double zinc ribbon DUF3593 PF12159.8 RJW72902.1 - 0.2 11.7 1.2 6.6 6.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) Nudix_N_2 PF14803.6 RJW72902.1 - 0.33 10.9 3.4 3.2 7.8 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal LicD PF04991.13 RJW72904.1 - 1.1e-06 29.0 0.1 9e-06 26.0 0.0 1.9 1 1 1 2 2 2 1 LicD family Kelch_3 PF13415.6 RJW72904.1 - 8.9 6.7 7.3 2 8.8 0.3 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Nuc_sug_transp PF04142.15 RJW72905.1 - 9.4e-37 126.8 14.3 7.2e-35 120.7 11.2 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter SLC35F PF06027.12 RJW72905.1 - 0.014 14.9 17.1 0.03 13.8 13.4 2.2 2 0 0 2 2 2 0 Solute carrier family 35 DUF4071 PF13281.6 RJW72906.1 - 1.1e-99 334.0 0.0 1.5e-99 333.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 RJW72906.1 - 4.6e-65 219.6 0.0 7.3e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW72906.1 - 4.8e-43 147.3 0.0 8.7e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW72906.1 - 0.00062 18.6 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RJW72906.1 - 0.007 15.7 0.0 0.03 13.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RJW72906.1 - 0.051 13.5 0.2 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 RJW72906.1 - 0.12 12.0 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 RIO1 family LMBR1 PF04791.16 RJW72910.1 - 1.3e-87 294.9 9.0 1.5e-87 294.7 9.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Trp_oprn_chp PF09534.10 RJW72910.1 - 0.18 11.6 0.2 0.63 9.8 0.1 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Iso_dh PF00180.20 RJW72911.1 - 3.8e-97 325.6 0.0 5.1e-97 325.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SOCS_box PF07525.16 RJW72911.1 - 8.5e-05 22.8 1.8 0.00023 21.5 1.8 1.8 1 0 0 1 1 1 1 SOCS box DHC_N1 PF08385.12 RJW72913.1 - 1.7e-10 40.2 0.1 2.7e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Synaphin PF05835.12 RJW72913.1 - 1.5 9.1 6.6 5.2 7.4 1.7 2.3 2 0 0 2 2 2 0 Synaphin protein DUF3695 PF12494.8 RJW72914.1 - 1.2e-10 41.1 2.2 1.9e-10 40.5 1.7 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3695) PLAC8 PF04749.17 RJW72916.1 - 6.9e-05 23.8 18.5 0.0005 21.0 18.5 2.5 1 1 0 1 1 1 1 PLAC8 family MIP PF00230.20 RJW72918.1 - 0.007 16.1 1.1 0.18 11.4 0.1 2.5 2 0 0 2 2 2 2 Major intrinsic protein Bestrophin PF01062.21 RJW72918.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel AAA_6 PF12774.7 RJW72919.1 - 1.2e-143 478.0 0.0 8e-143 475.3 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW72919.1 - 8e-124 413.7 6.1 8e-124 413.7 6.1 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RJW72919.1 - 1.2e-96 323.6 3.1 1.7e-96 323.1 0.0 2.8 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RJW72919.1 - 6.1e-93 310.9 0.0 1.8e-92 309.4 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RJW72919.1 - 3.3e-86 288.0 2.2 3.2e-85 284.8 0.8 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 RJW72919.1 - 5e-69 231.4 3.7 1.7e-64 216.7 0.1 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region DHC_N1 PF08385.12 RJW72919.1 - 1.7e-57 195.4 0.0 1.7e-57 195.4 0.0 3.8 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_lid_11 PF18198.1 RJW72919.1 - 4.6e-55 185.9 0.0 1.1e-54 184.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RJW72919.1 - 3.6e-49 167.6 5.3 7.3e-49 166.6 5.3 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RJW72919.1 - 7.4e-41 139.0 0.0 1.6e-39 134.7 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RJW72919.1 - 5.4e-26 91.2 0.0 4.2e-08 33.3 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RJW72919.1 - 4.1e-20 71.9 0.0 3e-19 69.1 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RJW72919.1 - 3.9e-17 62.5 0.0 2.2e-16 60.1 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 RJW72919.1 - 1.1e-07 32.4 0.1 0.15 12.5 0.0 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RJW72919.1 - 8.9e-06 26.0 0.4 4.2 7.7 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 RJW72919.1 - 0.00029 21.3 0.0 25 5.2 0.0 5.0 4 0 0 4 4 4 0 AAA ATPase domain Sigma54_activat PF00158.26 RJW72919.1 - 0.0078 15.9 0.1 1.1 9.0 0.0 3.6 3 0 0 3 3 3 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 RJW72919.1 - 0.11 12.6 0.0 0.64 10.1 0.0 2.3 2 0 0 2 2 1 0 Sigma-54 interaction domain DNA_photolyase PF00875.18 RJW72919.1 - 0.11 12.5 0.3 8.2 6.4 0.5 3.0 2 0 0 2 2 2 0 DNA photolyase ABC_tran PF00005.27 RJW72919.1 - 0.32 11.5 1.9 17 5.9 0.0 4.3 4 0 0 4 4 3 0 ABC transporter TRAM_LAG1_CLN8 PF03798.16 RJW72920.1 - 9.8e-31 107.0 21.3 2.3e-30 105.8 21.3 1.7 1 0 0 1 1 1 1 TLC domain Tubulin PF00091.25 RJW72921.1 - 1.8e-53 181.7 0.0 2.6e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW72921.1 - 1.8e-28 99.2 0.0 4e-28 98.1 0.0 1.6 1 1 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 RJW72921.1 - 0.0057 15.9 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Serglycin PF04360.12 RJW72921.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Serglycin Exo_endo_phos_2 PF14529.6 RJW72922.1 - 0.028 14.3 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase RVT_1 PF00078.27 RJW72923.1 - 2.3e-12 46.9 0.0 3.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cupin_8 PF13621.6 RJW72925.1 - 4.5e-34 118.3 0.0 6.9e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 RJW72925.1 - 0.0029 18.0 0.1 0.0083 16.5 0.1 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 RJW72925.1 - 0.0084 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 RJW72925.1 - 0.072 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Bravo_FIGEY PF13882.6 RJW72926.1 - 7.5e-19 68.9 6.7 1.9e-18 67.6 6.7 1.7 1 0 0 1 1 1 1 Bravo-like intracellular region DUF3324 PF11797.8 RJW72926.1 - 0.2 11.6 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) COesterase PF00135.28 RJW72927.1 - 5.5e-112 375.3 0.0 7.6e-112 374.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RJW72927.1 - 3e-08 33.8 0.1 6.1e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold UCH PF00443.29 RJW72929.1 - 1.3e-49 169.1 0.0 3.7e-49 167.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW72929.1 - 1.1e-20 74.5 1.9 5.3e-11 42.7 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ArfGap PF01412.18 RJW72932.1 - 4.1e-37 126.8 0.0 7.8e-37 125.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ARID PF01388.21 RJW72934.1 - 4.5e-14 52.9 0.0 9.8e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 RJW72934.1 - 2e-06 28.3 0.1 4.3e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain zf-C2H2_aberr PF17017.5 RJW72934.1 - 0.0092 16.1 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Aberrant zinc-finger FOXP-CC PF16159.5 RJW72934.1 - 0.098 13.3 4.5 1.4 9.6 0.1 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 RJW72934.1 - 0.11 13.0 1.5 0.48 11.0 1.5 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type Rtf2 PF04641.12 RJW72934.1 - 0.24 10.8 0.0 0.44 9.9 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C2H2_4 PF13894.6 RJW72934.1 - 6.3 7.9 5.9 4.6 8.4 1.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Cytochrom_C PF00034.21 RJW72935.1 - 1.8e-12 48.3 0.1 2.3e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 RJW72935.1 - 5.9e-07 29.7 1.6 3.4e-06 27.3 1.6 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 RJW72935.1 - 0.00011 21.9 0.2 0.00081 19.1 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain UPF0128 PF03673.13 RJW72935.1 - 0.017 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Dehyd-heme_bind PF09098.10 RJW72935.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding DUF4131 PF13567.6 RJW72936.1 - 6.2 6.4 6.1 3.4 7.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) HTH_Tnp_Tc5 PF03221.16 RJW72937.1 - 9.7e-07 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Keratin_assoc PF09775.9 RJW72937.1 - 0.03 14.0 0.3 0.059 13.0 0.3 1.6 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 LIF_OSM PF01291.17 RJW72937.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 LIF / OSM family iPGM_N PF06415.13 RJW72938.1 - 0.18 11.2 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) DnaJ PF00226.31 RJW72941.1 - 2.4e-17 62.8 3.9 5.6e-17 61.6 3.9 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 RJW72941.1 - 0.00025 20.8 0.0 0.00098 18.9 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 RJW72941.1 - 0.16 11.8 4.1 1.1 9.1 3.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) DUF1640 PF07798.11 RJW72941.1 - 0.18 11.9 12.5 0.26 11.3 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Allexi_40kDa PF05549.11 RJW72941.1 - 0.78 9.2 5.2 1.1 8.7 5.2 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4192 PF13830.6 RJW72941.1 - 2.1 8.4 9.7 2.8 7.9 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Presenilin PF01080.17 RJW72941.1 - 3.6 6.2 9.0 4.3 6.0 9.0 1.2 1 0 0 1 1 1 0 Presenilin FYDLN_acid PF09538.10 RJW72941.1 - 5.1 7.8 15.5 4.2 8.1 12.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2924 PF11149.8 RJW72941.1 - 5.7 7.3 12.5 7.7 6.9 11.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) Atg14 PF10186.9 RJW72941.1 - 9.7 5.2 15.6 13 4.7 15.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EGF PF00008.27 RJW72943.1 - 1.1e-07 31.9 28.8 5e-06 26.7 4.7 3.8 3 0 0 3 3 3 2 EGF-like domain TMEM154 PF15102.6 RJW72943.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Laminin_G_2 PF02210.24 RJW72943.1 - 0.009 16.6 0.0 0.84 10.2 0.0 2.3 2 0 0 2 2 2 1 Laminin G domain TMIE PF16038.5 RJW72943.1 - 0.014 15.2 8.0 0.025 14.4 8.0 1.3 1 0 0 1 1 1 0 TMIE protein EGF_3 PF12947.7 RJW72943.1 - 0.016 15.4 20.3 1.2 9.4 1.3 3.9 3 1 0 3 3 3 0 EGF domain cEGF PF12662.7 RJW72943.1 - 0.023 14.6 13.3 0.86 9.6 0.7 4.6 4 0 0 4 4 4 0 Complement Clr-like EGF-like TMEM52 PF14979.6 RJW72943.1 - 0.024 14.5 1.2 0.052 13.5 1.2 1.5 1 0 0 1 1 1 0 Transmembrane 52 Orthoreo_P10 PF07204.11 RJW72943.1 - 0.032 14.2 1.9 0.061 13.3 1.9 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 RJW72943.1 - 0.037 14.9 0.0 0.085 13.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 RJW72943.1 - 0.08 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame MLANA PF14991.6 RJW72943.1 - 0.082 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein melan-A DUF2207 PF09972.9 RJW72943.1 - 0.093 11.5 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Laminin_G_1 PF00054.23 RJW72943.1 - 0.1 12.8 0.0 6.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Laminin G domain SCIMP PF15050.6 RJW72943.1 - 0.14 12.6 2.2 0.3 11.6 2.2 1.5 1 0 0 1 1 1 0 SCIMP protein Prominin PF05478.11 RJW72943.1 - 0.16 9.9 5.6 0.23 9.4 5.6 1.1 1 0 0 1 1 1 0 Prominin Hum_adeno_E3A PF05393.11 RJW72943.1 - 0.18 11.8 2.6 0.34 10.9 2.6 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein EGF_CA PF07645.15 RJW72943.1 - 0.34 11.1 22.1 2.2 8.5 1.6 3.9 2 1 1 3 3 3 0 Calcium-binding EGF domain EGF_2 PF07974.13 RJW72943.1 - 0.51 10.8 27.6 0.11 12.9 5.0 3.9 3 2 0 3 3 3 0 EGF-like domain RCR PF12273.8 RJW72943.1 - 4.2 8.0 6.5 19 5.9 6.5 2.2 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red hEGF PF12661.7 RJW72943.1 - 6.5 7.6 20.8 2.4 8.9 1.3 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF RVT_1 PF00078.27 RJW72944.1 - 2e-07 30.8 0.0 4.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2058 PF09831.9 RJW72944.1 - 0.0063 16.7 5.1 0.0063 16.7 5.1 2.3 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2058) REV1_C PF16727.5 RJW72944.1 - 0.048 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain DUF1957 PF09210.11 RJW72944.1 - 1.6 9.2 6.0 0.2 12.1 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) IHABP4_N PF16174.5 RJW72944.1 - 3.8 8.1 21.8 0.84 10.2 17.0 2.0 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Presenilin PF01080.17 RJW72944.1 - 6.8 5.3 5.2 13 4.5 5.2 1.4 1 0 0 1 1 1 0 Presenilin LTD PF00932.19 RJW72945.1 - 1.3e-09 38.4 0.0 1.9e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Lamin Tail Domain PIF6 PF05341.11 RJW72945.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Per os infectivity factor 6 zf-A20 PF01754.16 RJW72946.1 - 2e-12 46.8 8.9 2e-12 46.8 8.9 2.3 2 0 0 2 2 2 1 A20-like zinc finger Helicase_C PF00271.31 RJW72947.1 - 3.9e-21 75.5 0.0 2e-20 73.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RJW72947.1 - 3.6e-18 65.5 0.6 7.4e-18 64.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Nab1 PF04902.12 RJW72947.1 - 0.0097 16.3 1.1 0.016 15.6 1.1 1.3 1 0 0 1 1 1 1 Conserved region in Nab1 PAP_assoc PF03828.19 RJW72948.1 - 6.1e-14 52.0 0.0 1.2e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Mitofilin PF09731.9 RJW72948.1 - 0.15 10.8 4.4 0.2 10.5 4.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tubulin PF00091.25 RJW72950.1 - 1.4e-48 165.7 0.0 4.2e-48 164.2 0.0 1.9 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RJW72950.1 - 1.4e-22 80.2 0.0 2.8e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RJW72950.1 - 1.7e-05 24.6 0.4 0.00049 19.8 0.0 2.8 2 1 1 3 3 3 1 Tubulin domain PAP_assoc PF03828.19 RJW72951.1 - 1.3e-09 38.1 0.0 3.5e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Antibiotic_NAT PF02522.14 RJW72951.1 - 0.047 13.5 0.8 1.4 8.6 0.2 2.4 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase Ras PF00071.22 RJW72952.1 - 1.8e-47 160.9 0.0 2.4e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW72952.1 - 3.7e-27 94.9 0.0 6e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW72952.1 - 9.5e-08 31.7 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RJW72952.1 - 0.00095 19.1 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 RJW72952.1 - 0.0069 16.5 0.0 0.01 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 RJW72952.1 - 0.0092 15.5 0.0 0.031 13.8 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RJW72952.1 - 0.019 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 RJW72952.1 - 0.077 13.3 0.0 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain zf-met PF12874.7 RJW72955.1 - 3.4e-06 27.2 6.3 0.028 14.8 0.6 4.1 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW72955.1 - 1.9e-05 24.8 3.0 0.1 12.9 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding ANAPC4_WD40 PF12894.7 RJW72955.1 - 0.0028 17.9 0.0 0.18 12.1 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RJW72955.1 - 0.031 15.2 0.5 66 4.6 0.2 4.4 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_2 PF13360.6 RJW72955.1 - 0.064 12.8 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 PQQ-like domain DUF2730 PF10805.8 RJW72955.1 - 0.28 11.3 1.4 0.62 10.2 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) YabA PF06156.13 RJW72955.1 - 0.5 11.0 3.7 1.3 9.7 3.7 1.7 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 RJW72955.1 - 0.54 10.1 2.4 1.1 9.1 2.4 1.4 1 0 0 1 1 1 0 Septum formation initiator zf-C2H2 PF00096.26 RJW72955.1 - 0.57 10.7 8.0 4.5 7.9 0.7 4.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type CENP-H PF05837.12 RJW72955.1 - 1.1 9.7 9.7 0.042 14.3 2.3 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Ig_3 PF13927.6 RJW72959.1 - 6.7e-29 100.3 0.6 1.6e-08 35.0 0.0 4.3 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 RJW72959.1 - 1e-21 76.8 0.0 4.6e-06 26.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 RJW72959.1 - 5.1e-16 58.6 0.2 0.00081 19.5 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 RJW72959.1 - 5.4e-16 58.7 1.4 0.00031 20.9 0.0 5.9 4 2 2 6 6 6 3 Immunoglobulin V-set domain Ig_2 PF13895.6 RJW72959.1 - 3.3e-14 53.0 0.1 0.00053 20.3 0.0 4.2 3 1 1 4 4 4 3 Immunoglobulin domain Ig_6 PF18452.1 RJW72959.1 - 5.3e-05 22.7 0.0 0.81 9.3 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 RJW72959.1 - 0.00015 21.7 0.0 0.71 10.0 0.0 3.6 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain fn3 PF00041.21 RJW72959.1 - 0.057 13.8 3.8 6.6 7.2 0.0 4.1 3 1 0 3 3 3 0 Fibronectin type III domain LRR_4 PF12799.7 RJW72962.1 - 8.1e-09 35.6 16.5 0.032 14.7 0.3 6.6 4 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RJW72962.1 - 1.4e-06 27.9 20.1 0.2 11.8 0.2 8.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.6 RJW72962.1 - 0.00079 19.1 9.2 0.41 10.4 0.2 5.2 5 0 0 5 5 5 2 Leucine rich repeat F-box-like PF12937.7 RJW72962.1 - 0.0017 18.2 0.1 0.0051 16.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like PHD PF00628.29 RJW72962.1 - 0.04 13.8 0.2 0.2 11.5 0.2 2.3 1 0 0 1 1 1 0 PHD-finger F-box PF00646.33 RJW72962.1 - 0.05 13.5 2.8 0.12 12.3 0.6 2.7 2 0 0 2 2 2 0 F-box domain HTH_Tnp_ISL3 PF13542.6 RJW72962.1 - 0.16 11.4 0.7 4.2 6.9 0.1 3.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 fn2 PF00040.19 RJW72964.1 - 9.5e-17 61.0 33.5 1.4e-08 34.8 7.8 6.7 4 2 0 4 4 4 3 Fibronectin type II domain WRC PF08879.10 RJW72965.1 - 9 6.1 8.5 29 4.5 0.1 2.5 2 0 0 2 2 2 0 WRC PRIMA1 PF16101.5 RJW72966.1 - 2.1 8.4 7.0 2.5 8.1 3.0 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Peptidase_C1 PF00112.23 RJW72967.1 - 4.9e-47 160.8 0.0 6.9e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RJW72967.1 - 3.5e-12 46.6 0.5 5.5e-12 45.9 0.5 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Asp PF00026.23 RJW72968.1 - 9.5e-49 166.5 0.0 1.1e-48 166.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RJW72968.1 - 1.5e-11 44.9 2.4 1.3e-08 35.2 1.1 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DHC_N1 PF08385.12 RJW72969.1 - 2.7e-130 435.7 5.9 4e-130 435.1 5.9 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 PSK_trans_fac PF07704.11 RJW72969.1 - 0.065 14.0 1.1 0.35 11.6 1.1 2.4 1 0 0 1 1 1 0 Rv0623-like transcription factor Miff PF05644.11 RJW72970.1 - 0.00015 21.5 0.4 0.00035 20.3 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial and peroxisomal fission factor Mff DUF2207 PF09972.9 RJW72970.1 - 0.088 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Atg14 PF10186.9 RJW72970.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4199 PF13858.6 RJW72970.1 - 1.2 9.5 3.4 2.1 8.7 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PHD PF00628.29 RJW72971.1 - 3.1e-05 23.8 3.2 9.9e-05 22.2 1.5 2.3 2 0 0 2 2 2 1 PHD-finger PLAC8 PF04749.17 RJW72972.1 - 3.7e-07 31.0 21.2 4.9e-07 30.7 21.2 1.2 1 0 0 1 1 1 1 PLAC8 family Peptidase_S9 PF00326.21 RJW72974.1 - 2.6e-49 167.6 1.1 4.1e-49 166.9 1.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 RJW72974.1 - 5e-44 150.5 0.1 6.9e-44 150.0 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DLH PF01738.18 RJW72974.1 - 8.1e-06 25.5 0.0 3.1e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 RJW72974.1 - 0.003 18.2 0.5 0.023 15.3 0.0 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family Ribosomal_L6e PF01159.19 RJW72977.1 - 1.2e-25 90.2 0.0 1.2e-25 90.2 0.0 5.0 6 0 0 6 6 6 1 Ribosomal protein L6e EF-hand_7 PF13499.6 RJW72977.1 - 1.4e-06 28.7 0.0 5.6e-06 26.7 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RJW72977.1 - 0.0004 20.1 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 RJW72977.1 - 0.00052 19.4 0.3 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 RJW72977.1 - 0.0045 17.3 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain GRIP PF01465.20 RJW72980.1 - 2.1e-12 46.7 0.3 5.5e-12 45.4 0.3 1.8 1 0 0 1 1 1 1 GRIP domain Rab_bind PF16704.5 RJW72980.1 - 1.4e-09 37.8 2.2 1.4e-09 37.8 2.2 4.1 4 0 0 4 4 4 1 Rab binding domain SPATA1_C PF15743.5 RJW72980.1 - 0.0029 17.7 0.5 0.0029 17.7 0.5 6.1 5 1 0 5 5 5 1 Spermatogenesis-associated C-terminus Luteo_Vpg PF01659.16 RJW72980.1 - 0.31 11.4 5.0 1.3 9.4 5.0 2.1 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein DUF2120 PF09893.9 RJW72980.1 - 2.5 8.2 0.0 2.5 8.2 0.0 3.7 4 2 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2120) Citrate_bind PF16114.5 RJW72981.1 - 1.9e-86 288.1 0.0 3e-86 287.4 0.0 1.3 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 RJW72981.1 - 1.7e-17 63.5 0.0 9.5e-17 61.1 0.0 1.8 1 1 1 2 2 2 1 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 RJW72981.1 - 1.5e-14 54.0 0.1 3.5e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_2 PF08442.10 RJW72981.1 - 1.4e-08 34.5 0.0 3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 RJW72981.1 - 0.00072 19.4 0.2 0.002 18.0 0.2 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding PF02629.19 RJW72981.1 - 0.014 16.1 0.0 0.039 14.6 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain DUF4949 PF16307.5 RJW72981.1 - 0.053 13.6 0.0 4.1 7.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4949) Ras PF00071.22 RJW72982.1 - 2.3e-58 196.4 0.1 3.8e-58 195.6 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW72982.1 - 1.7e-32 112.1 0.1 3.5e-32 111.1 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW72982.1 - 7.8e-11 41.7 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RJW72982.1 - 4.4e-06 26.7 0.0 8.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RJW72982.1 - 0.0017 17.9 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 RJW72982.1 - 0.037 14.3 0.5 0.15 12.3 0.1 2.2 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RJW72982.1 - 0.043 13.7 0.1 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Med10 PF09748.9 RJW72985.1 - 2.4e-31 108.2 0.1 2.9e-31 108.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Syntaxin PF00804.25 RJW72985.1 - 0.013 15.2 0.8 0.19 11.4 0.1 2.1 2 0 0 2 2 2 0 Syntaxin DUF601 PF04642.12 RJW72985.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Ribosomal_S27e PF01667.17 RJW72986.1 - 3.8e-22 77.8 1.8 6.6e-22 77.0 1.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S27 WD40 PF00400.32 RJW72987.1 - 0.00031 21.5 6.9 4.3 8.4 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW72987.1 - 0.032 14.5 0.0 8.2 6.8 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Atg14 PF10186.9 RJW72987.1 - 0.47 9.5 5.3 0.82 8.7 5.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MRP-L28 PF09812.9 RJW72988.1 - 2.3e-28 99.4 7.7 2.3e-28 99.4 7.7 2.7 3 0 0 3 3 3 2 Mitochondrial ribosomal protein L28 Alba PF01918.21 RJW72989.1 - 1.1e-06 28.4 0.4 2.5e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 Alba EF-hand_1 PF00036.32 RJW72991.1 - 4e-28 94.8 11.0 3e-08 32.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW72991.1 - 9.1e-25 86.9 4.1 9.6e-12 45.2 1.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW72991.1 - 1.3e-22 78.3 8.2 1.4e-06 27.5 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RJW72991.1 - 4.2e-21 73.0 6.5 2e-06 27.3 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RJW72991.1 - 1.7e-16 59.8 11.6 3.3e-08 33.3 1.5 4.2 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW72991.1 - 2.6e-08 34.2 0.2 0.0024 18.2 0.0 2.7 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW72991.1 - 7.7e-06 25.8 0.4 0.015 15.2 0.0 2.5 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RJW72991.1 - 9.3e-06 25.9 0.0 7.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain TerB PF05099.13 RJW72991.1 - 0.00062 19.7 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 1 Tellurite resistance protein TerB Acetyltransf_6 PF13480.7 RJW72991.1 - 0.01 16.0 0.2 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dockerin_1 PF00404.18 RJW72991.1 - 0.055 13.7 4.7 1.5 9.1 0.2 3.2 2 2 0 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 RJW72991.1 - 0.066 13.1 0.7 2.1 8.2 0.0 3.0 2 1 1 3 3 3 0 Caleosin related protein CSRNP_N PF16019.5 RJW72992.1 - 1.8e-21 77.1 13.1 1.8e-21 77.1 13.1 1.8 3 0 0 3 3 3 1 Cysteine/serine-rich nuclear protein N-terminus EGF PF00008.27 RJW72996.1 - 5.1e-10 39.5 33.2 0.0025 18.1 6.3 3.6 3 0 0 3 3 3 3 EGF-like domain EGF_2 PF07974.13 RJW72996.1 - 9.5e-07 29.1 37.1 0.028 14.8 6.4 3.4 3 0 0 3 3 3 3 EGF-like domain SEA PF01390.20 RJW72996.1 - 0.00053 20.0 0.0 0.00094 19.3 0.0 1.4 1 0 0 1 1 1 1 SEA domain hEGF PF12661.7 RJW72996.1 - 0.0028 18.2 31.0 0.077 13.7 5.1 4.1 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_3 PF12947.7 RJW72996.1 - 0.023 14.9 4.6 0.023 14.9 4.6 3.5 4 0 0 4 4 4 0 EGF domain FXa_inhibition PF14670.6 RJW72996.1 - 0.041 14.2 4.7 0.041 14.2 4.7 3.6 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site BPL_LplA_LipB PF03099.19 RJW73000.1 - 2.7e-07 30.6 0.0 1.1e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 RJW73000.1 - 0.00025 20.9 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain RVT_1 PF00078.27 RJW73002.1 - 2.7e-41 141.5 0.0 7.7e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW73002.1 - 5.6e-07 29.4 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase NopRA1 PF16201.5 RJW73003.1 - 8.6e-44 149.5 0.6 1.8e-42 145.2 0.1 3.1 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 RJW73003.1 - 1.3e-38 133.2 3.6 2.1e-38 132.6 2.0 2.0 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Pkinase PF00069.25 RJW73005.1 - 4e-25 88.7 0.0 6e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW73005.1 - 9.3e-13 48.1 0.0 1.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW73005.1 - 9.3e-09 34.5 0.0 1.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LEDGF PF11467.8 RJW73006.1 - 9.7e-07 28.4 0.8 9.7e-07 28.4 0.8 1.9 2 0 0 2 2 2 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.17 RJW73006.1 - 0.0059 17.0 3.3 0.023 15.1 0.0 2.8 2 0 0 2 2 2 1 PWWP domain Phage_cap_E PF03864.15 RJW73006.1 - 0.36 10.0 6.0 2.5 7.2 0.3 2.4 2 0 0 2 2 2 0 Phage major capsid protein E DHC_N1 PF08385.12 RJW73008.1 - 4.6e-27 94.9 2.3 4.9e-27 94.8 2.3 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 CCDC154 PF15450.6 RJW73008.1 - 0.012 14.2 0.5 0.016 13.8 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 zf-C2H2 PF00096.26 RJW73010.1 - 0.016 15.6 0.3 0.042 14.3 0.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type TTC5_OB PF16669.5 RJW73011.1 - 6.4e-39 132.2 0.0 1.1e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_2 PF07719.17 RJW73011.1 - 3e-10 39.4 0.0 5.8e-06 26.0 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 RJW73011.1 - 2.3e-09 36.8 0.0 0.00029 20.5 0.0 4.0 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.28 RJW73011.1 - 1.2e-08 34.4 0.0 0.00011 21.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RJW73011.1 - 5.6e-08 32.6 0.4 0.21 12.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW73011.1 - 7.3e-07 29.7 0.1 0.047 14.3 0.0 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW73011.1 - 2.3e-06 28.0 0.9 0.00031 21.3 0.0 4.5 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RJW73011.1 - 4.2e-06 26.6 0.0 0.00029 20.8 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW73011.1 - 0.00019 21.6 0.4 0.0015 18.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Smac_DIABLO PF09057.10 RJW73011.1 - 0.00062 19.2 0.1 0.34 10.2 0.0 2.5 2 0 0 2 2 2 2 Second Mitochondria-derived Activator of Caspases TPR_19 PF14559.6 RJW73011.1 - 0.0074 16.8 0.0 0.44 11.1 0.0 3.4 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF1561 PF07598.11 RJW73012.1 - 0.0074 14.6 0.0 0.011 14.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1561) SKG6 PF08693.10 RJW73012.1 - 0.032 13.6 1.9 0.072 12.5 1.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 RJW73012.1 - 0.29 11.2 2.4 0.51 10.4 2.4 1.3 1 0 0 1 1 1 0 Podoplanin tRNA-synt_1b PF00579.25 RJW73013.1 - 1.1e-38 133.3 0.0 2.1e-31 109.4 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 RJW73013.1 - 7.8e-21 74.0 0.0 2.6e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Putative tRNA binding domain PKD_channel PF08016.12 RJW73014.1 - 2.4e-131 438.3 14.5 2.4e-131 438.3 14.5 2.1 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 RJW73014.1 - 4.2e-23 81.8 29.9 4.2e-23 81.8 29.9 2.1 2 0 0 2 2 2 1 Ion transport protein THOC7 PF05615.13 RJW73014.1 - 0.022 15.0 0.2 0.022 15.0 0.2 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 EF-hand_7 PF13499.6 RJW73014.1 - 0.03 14.7 0.8 0.34 11.4 0.2 2.8 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_8 PF13833.6 RJW73014.1 - 0.073 12.9 0.2 0.22 11.4 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair ADIP PF11559.8 RJW73014.1 - 1.9 8.5 7.0 7.7 6.6 0.6 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Kinesin PF00225.23 RJW73015.1 - 5.2e-56 190.0 0.0 7.4e-35 120.4 0.0 2.7 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 RJW73015.1 - 3.1e-33 114.8 0.0 1.3e-32 112.8 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding DivIVA PF05103.13 RJW73015.1 - 0.0074 16.4 10.4 0.0074 16.4 10.4 2.6 2 0 0 2 2 2 1 DivIVA protein AAA_24 PF13479.6 RJW73015.1 - 0.092 12.5 0.3 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Flot PF15975.5 RJW73015.1 - 0.25 11.5 3.7 0.6 10.3 3.7 1.6 1 0 0 1 1 1 0 Flotillin Spc7 PF08317.11 RJW73015.1 - 0.37 9.6 15.8 0.9 8.4 15.8 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 RJW73015.1 - 0.68 10.1 9.8 0.1 12.8 4.8 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_22 PF13401.6 RJW73015.1 - 2.8 8.2 4.8 12 6.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain XhlA PF10779.9 RJW73015.1 - 3.5 7.9 5.3 1.5 9.1 1.7 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Cnn_1N PF07989.11 RJW73015.1 - 9.6 6.5 16.0 0.52 10.5 1.6 4.2 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 TMPIT PF07851.13 RJW73015.1 - 9.7 5.3 5.7 25 4.0 5.7 1.6 1 0 0 1 1 1 0 TMPIT-like protein AKAP28 PF14469.6 RJW73016.1 - 0.089 12.6 0.0 0.089 12.6 0.0 1.1 1 0 0 1 1 1 0 28 kDa A-kinase anchor Mito_carr PF00153.27 RJW73017.1 - 2.6e-50 168.3 3.0 2e-16 59.7 0.0 3.3 2 2 1 3 3 3 3 Mitochondrial carrier protein MAS20 PF02064.15 RJW73018.1 - 1.3e-19 70.6 0.1 1.5e-19 70.3 0.1 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor Ets PF00178.22 RJW73019.1 - 1.7e-34 118.1 0.3 3e-34 117.3 0.3 1.4 1 0 0 1 1 1 1 Ets-domain UPAR_LY6_2 PF16975.5 RJW73019.1 - 0.012 15.8 0.2 0.031 14.5 0.2 1.6 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Galactosyl_T PF01762.21 RJW73020.1 - 1.7e-15 57.3 0.0 2.6e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase SelR PF01641.18 RJW73021.1 - 5.8e-44 149.1 0.9 1.5e-24 86.4 0.1 2.1 1 1 1 2 2 2 2 SelR domain DUF4498 PF14926.6 RJW73022.1 - 5.6e-49 166.7 0.1 6.9e-49 166.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) PDZ PF00595.24 RJW73023.1 - 1.4e-32 111.8 2.9 7.4e-16 58.3 0.1 4.6 5 0 0 5 5 5 3 PDZ domain PDZ_6 PF17820.1 RJW73023.1 - 1.4e-27 95.3 0.5 7.9e-10 38.4 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 RJW73023.1 - 4.2e-14 52.6 0.1 0.0033 17.7 0.0 4.3 4 0 0 4 4 4 3 PDZ domain PDZ_4 PF17816.1 RJW73023.1 - 0.00015 22.1 0.0 1.6 9.1 0.0 3.0 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 RJW73023.1 - 0.0014 18.6 0.4 14 5.7 0.1 3.9 4 0 0 4 4 4 2 Tricorn protease PDZ domain Cadherin PF00028.17 RJW73025.1 - 4.3e-86 283.5 0.8 2.8e-13 50.1 0.0 7.4 7 0 0 7 7 7 7 Cadherin domain Cadherin_pro PF08758.11 RJW73025.1 - 7.6e-07 29.2 0.0 5.5e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 Cadherin prodomain like Cadherin_2 PF08266.12 RJW73025.1 - 0.001 18.8 0.0 13 5.7 0.0 4.9 5 0 0 5 5 5 1 Cadherin-like TF_Otx PF03529.13 RJW73025.1 - 0.037 14.4 1.8 0.074 13.5 1.1 1.8 1 1 0 1 1 1 0 Otx1 transcription factor Meleagrin PF08189.11 RJW73026.1 - 0.79 9.5 2.6 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 Meleagrin/Cygnin family G-alpha PF00503.20 RJW73027.1 - 9.8e-124 413.1 6.2 1.3e-123 412.7 6.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RJW73027.1 - 1.4e-17 63.7 2.9 2.2e-13 50.1 0.7 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RJW73027.1 - 6.1e-06 25.8 4.3 0.00047 19.6 1.7 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 RJW73027.1 - 0.00024 21.3 3.1 0.18 12.0 0.4 2.7 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RJW73027.1 - 0.0056 16.3 2.1 0.23 11.0 0.5 2.4 2 0 0 2 2 2 1 Ras family TniB PF05621.11 RJW73027.1 - 0.011 15.1 0.1 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 RJW73027.1 - 0.071 12.9 0.3 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 RJW73027.1 - 0.18 11.1 0.2 0.53 9.6 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family RVT_1 PF00078.27 RJW73029.1 - 3.4e-45 154.3 0.0 8.6e-45 152.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PA PF02225.22 RJW73029.1 - 8e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 PA domain DEC1 PF15859.5 RJW73029.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family DUF1624 PF07786.12 RJW73030.1 - 0.021 14.4 2.2 0.039 13.5 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) CitMHS PF03600.16 RJW73030.1 - 0.021 14.1 1.1 1.9 7.6 0.2 2.2 2 0 0 2 2 2 0 Citrate transporter Quaking_NLS PF16551.5 RJW73030.1 - 0.15 11.8 0.4 0.3 10.8 0.4 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking PUB PF09409.10 RJW73031.1 - 2.1e-07 30.8 0.0 4.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 RJW73031.1 - 0.0035 17.5 0.0 0.063 13.5 0.0 2.9 2 1 0 2 2 2 1 UBX domain Homeodomain PF00046.29 RJW73032.1 - 4.4e-22 77.7 3.7 1e-21 76.5 3.7 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RJW73032.1 - 0.025 14.5 0.8 0.05 13.5 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain p25-alpha PF05517.12 RJW73033.1 - 6.1e-46 156.4 4.2 6.9e-46 156.2 4.2 1.0 1 0 0 1 1 1 1 p25-alpha Galactosyl_T PF01762.21 RJW73035.1 - 1.7e-15 57.3 0.0 2.6e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase tRNA-synt_2d PF01409.20 RJW73036.1 - 6.9e-49 166.5 0.3 7.1e-29 101.0 0.1 2.5 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 RJW73036.1 - 1.2e-17 64.1 0.0 3.8e-17 62.5 0.0 1.9 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Forkhead PF00250.18 RJW73037.1 - 1.6e-25 89.1 0.3 3.4e-25 88.1 0.3 1.5 1 0 0 1 1 1 1 Forkhead domain MRI PF15325.6 RJW73037.1 - 1 10.5 0.0 1 10.5 0.0 3.3 3 0 0 3 3 3 0 Modulator of retrovirus infection RVT_1 PF00078.27 RJW73038.1 - 2.6e-12 46.7 0.0 4.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.22 RJW73039.1 - 1.9e-57 193.4 0.0 2.2e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RJW73039.1 - 3.8e-23 82.0 0.0 6.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RJW73039.1 - 2.7e-10 40.0 0.0 4.8e-10 39.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RJW73039.1 - 5.9e-05 22.7 0.1 0.0001 21.9 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RJW73039.1 - 0.0014 18.5 0.0 0.0073 16.2 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 RJW73039.1 - 0.037 13.4 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RJW73039.1 - 0.04 13.3 0.0 0.083 12.3 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 RJW73039.1 - 0.15 11.8 0.0 9.2 6.0 0.0 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation zf-C2H2_4 PF13894.6 RJW73041.1 - 0.018 15.8 35.5 2.2 9.3 0.4 6.8 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.7 RJW73041.1 - 0.03 14.7 4.4 2.1 8.8 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RJW73041.1 - 0.2 11.5 0.1 0.2 11.5 0.1 4.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 RJW73041.1 - 0.35 11.4 0.1 0.35 11.4 0.1 6.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RJW73041.1 - 0.57 10.3 7.4 5.4 7.1 0.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 RJW73041.1 - 2.7 8.5 4.5 3.7 8.1 0.0 3.2 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger IBR PF01485.21 RJW73041.1 - 4.2 7.7 6.5 2.4 8.5 2.8 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain YacG PF03884.14 RJW73043.1 - 0.039 13.7 0.3 0.079 12.7 0.3 1.5 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG GPDPase_memb PF10110.9 RJW73043.1 - 0.051 12.4 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Ribosomal_S15 PF00312.22 RJW73044.1 - 2.5e-14 53.3 0.2 3e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S15 PDZ PF00595.24 RJW73046.1 - 5.1e-64 212.6 0.1 9e-14 51.6 0.1 6.8 7 0 0 7 7 7 6 PDZ domain PDZ_6 PF17820.1 RJW73046.1 - 1.7e-50 168.6 3.0 2.8e-12 46.3 0.1 6.4 6 0 0 6 6 6 6 PDZ domain PDZ_2 PF13180.6 RJW73046.1 - 5.2e-24 84.4 0.0 0.001 19.3 0.0 6.4 6 0 0 6 6 6 5 PDZ domain Galactosyl_T PF01762.21 RJW73049.1 - 2.1e-33 115.8 0.0 2.7e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Glycos_transf_2 PF00535.26 RJW73049.1 - 0.0014 18.4 0.1 1.8 8.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 2 BACK PF07707.15 RJW73050.1 - 2.3e-18 66.2 0.5 6.2e-18 64.8 0.2 1.9 2 1 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 RJW73050.1 - 1.5e-07 31.6 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 RJW73050.1 - 0.0035 17.5 0.2 0.13 12.4 0.0 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3342) Kelch_1 PF01344.25 RJW73051.1 - 1.7e-47 158.8 0.6 2.8e-11 42.8 0.0 4.1 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 RJW73051.1 - 2.2e-29 100.7 0.1 4.7e-07 29.9 0.0 4.2 2 2 2 4 4 4 4 Kelch motif Kelch_2 PF07646.15 RJW73051.1 - 3.6e-18 64.8 0.0 1.4e-06 28.0 0.0 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 RJW73051.1 - 4.7e-16 58.6 3.5 0.001 19.3 0.1 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.6 RJW73051.1 - 7.1e-15 54.8 0.9 0.0051 16.8 0.0 4.2 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW73051.1 - 8.1e-08 32.1 6.8 0.41 10.7 0.0 4.5 5 0 0 5 5 5 3 Kelch motif PQQ_3 PF13570.6 RJW73051.1 - 0.0038 17.7 1.6 12 6.5 0.0 3.6 4 0 0 4 4 4 2 PQQ-like domain RVT_1 PF00078.27 RJW73052.1 - 4.9e-46 157.0 0.5 1.4e-45 155.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW73052.1 - 1.4e-11 44.2 0.2 1e-10 41.5 0.0 2.6 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase Kelch_1 PF01344.25 RJW73054.1 - 2.8e-58 193.2 7.6 6.2e-11 41.7 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RJW73054.1 - 1.6e-37 126.6 4.5 1.1e-06 28.7 0.0 6.2 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 RJW73054.1 - 1e-21 76.0 1.3 3.1e-06 26.9 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RJW73054.1 - 1.3e-20 73.2 10.0 0.0023 18.2 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RJW73054.1 - 2.6e-19 69.0 7.4 0.011 15.7 0.0 6.3 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW73054.1 - 3.2e-08 33.4 9.5 1.7 8.7 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Clat_adaptor_s PF01217.20 RJW73055.1 - 8.5e-56 187.8 3.1 1.1e-55 187.5 3.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HAUS6_N PF14661.6 RJW73056.1 - 0.014 15.0 0.0 0.039 13.5 0.0 1.8 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Gemini_BL1 PF00845.19 RJW73056.1 - 0.035 13.7 0.2 0.083 12.5 0.2 1.6 1 0 0 1 1 1 0 Geminivirus BL1 movement protein Ribonuclease_T2 PF00445.18 RJW73056.1 - 0.13 12.5 0.0 9.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease T2 family ASTN_2_hairpin PF18577.1 RJW73057.1 - 0.0058 16.7 0.1 0.25 11.5 0.0 2.4 2 0 0 2 2 2 2 Astrotactin-2 C-terminal beta-hairpin domain Cpn60_TCP1 PF00118.24 RJW73062.1 - 2.6e-161 537.6 0.4 3.2e-161 537.3 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WW PF00397.26 RJW73063.1 - 0.00019 21.4 2.2 0.0006 19.8 2.2 2.0 1 0 0 1 1 1 1 WW domain RVT_1 PF00078.27 RJW73065.1 - 2.5e-06 27.2 0.0 2.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L15e PF00827.17 RJW73066.1 - 2.8e-92 307.7 9.6 3.1e-92 307.5 9.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 7tm_1 PF00001.21 RJW73068.1 - 7.1e-14 51.8 12.7 9.7e-14 51.3 12.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Phage_holin_3_5 PF16085.5 RJW73068.1 - 0.63 10.2 3.4 1.7 8.8 3.4 1.8 1 1 0 1 1 1 0 Bacteriophage holin Hol, superfamily III TSP_1 PF00090.19 RJW73071.1 - 1.8e-09 37.6 6.9 1.8e-09 37.6 6.9 2.6 2 0 0 2 2 2 1 Thrombospondin type 1 domain Somatomedin_B PF01033.17 RJW73071.1 - 0.0034 17.7 23.4 0.0034 17.7 23.4 3.2 3 1 0 3 3 3 1 Somatomedin B domain GKAP PF03359.13 RJW73073.1 - 9.4e-24 84.6 11.2 3.5e-23 82.7 11.2 2.0 1 1 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein Ion_trans PF00520.31 RJW73074.1 - 3.7e-182 602.7 65.9 2.5e-63 213.6 15.3 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 RJW73074.1 - 2.5e-26 91.7 0.1 5.7e-26 90.5 0.1 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 RJW73074.1 - 3e-25 87.7 0.1 7.7e-25 86.4 0.1 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 RJW73074.1 - 2.7e-13 49.4 64.5 5e-07 28.7 3.9 8.0 5 3 2 7 7 7 5 Polycystin cation channel DZR PF12773.7 RJW73076.1 - 1.1e-17 63.8 31.4 5.4e-07 29.5 5.4 4.2 2 1 2 5 5 5 5 Double zinc ribbon Ank_2 PF12796.7 RJW73076.1 - 2.2e-12 47.4 0.0 1.3e-11 45.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW73076.1 - 3.7e-11 42.2 0.0 0.0012 19.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RJW73076.1 - 4.9e-10 39.4 0.7 0.0073 16.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat CHB_HEX_C_1 PF13290.6 RJW73076.1 - 2.6e-09 37.0 0.9 5.1e-09 36.0 0.9 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Ank_4 PF13637.6 RJW73076.1 - 3.4e-09 37.0 0.0 5e-05 23.8 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) zinc_ribbon_2 PF13240.6 RJW73076.1 - 4.5e-09 35.7 51.7 5.5e-06 25.9 1.8 6.3 5 1 0 5 5 5 2 zinc-ribbon domain Ank_5 PF13857.6 RJW73076.1 - 1.4e-08 34.8 0.0 2.7e-07 30.7 0.1 3.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Fn3_assoc PF13287.6 RJW73076.1 - 3.4e-08 33.5 0.3 8.2e-08 32.3 0.3 1.7 1 0 0 1 1 1 1 Fn3 associated zinc_ribbon_15 PF17032.5 RJW73076.1 - 4.9e-06 27.2 26.1 0.034 14.9 0.2 5.1 3 1 1 4 4 4 2 zinc-ribbon family zf-ribbon_3 PF13248.6 RJW73076.1 - 9.8e-05 21.6 37.5 0.00014 21.1 1.4 5.5 5 1 0 5 5 5 3 zinc-ribbon domain NOB1_Zn_bind PF08772.11 RJW73076.1 - 0.038 14.1 21.7 0.17 12.1 0.3 4.8 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like zinc-ribbons_6 PF07191.12 RJW73076.1 - 0.14 12.1 23.8 5.9 7.0 0.1 4.6 3 1 1 4 4 4 0 zinc-ribbons RNA_POL_M_15KD PF02150.16 RJW73076.1 - 0.55 10.2 0.0 0.55 10.2 0.0 5.3 3 2 2 5 5 5 0 RNA polymerases M/15 Kd subunit tRNA_int_endo PF01974.17 RJW73079.1 - 3e-14 52.9 0.0 5.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain RNase_HII PF01351.18 RJW73079.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease HII PGM_PMM_II PF02879.16 RJW73079.1 - 0.13 12.9 0.0 1.8 9.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II TMEM164 PF14808.6 RJW73080.1 - 1.6e-92 309.4 8.5 2.2e-92 309.0 8.5 1.2 1 0 0 1 1 1 1 TMEM164 family WD40 PF00400.32 RJW73080.1 - 4e-17 62.3 2.0 0.0021 18.8 0.0 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73080.1 - 0.043 14.1 0.0 18 5.7 0.0 3.2 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 RJW73082.1 - 6.2e-70 235.6 0.0 1.1e-69 234.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW73082.1 - 1.2e-38 132.9 0.0 1.9e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 RJW73082.1 - 1.4e-38 130.8 0.5 1.6e-18 66.6 0.1 2.4 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 RJW73082.1 - 2.8e-09 36.7 0.0 2e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 RJW73082.1 - 0.00013 20.9 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Clathrin PF00637.20 RJW73083.1 - 6.5e-153 502.7 26.5 8.3e-33 113.3 2.2 5.1 5 0 0 5 5 5 5 Region in Clathrin and VPS TPR_14 PF13428.6 RJW73083.1 - 5.7e-08 32.9 3.7 3.5 8.7 0.1 7.0 5 1 1 6 6 6 3 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 RJW73083.1 - 2.7e-06 26.7 0.1 0.0021 17.2 0.0 2.4 2 0 0 2 2 2 2 Coatomer WD associated region TPR_7 PF13176.6 RJW73083.1 - 2.8e-05 23.8 5.3 7.8 6.8 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW73083.1 - 0.00014 21.7 0.8 1.5 9.1 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 RJW73083.1 - 0.0018 18.0 1.9 4.2 7.4 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW73083.1 - 0.002 18.2 3.1 25 5.4 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 RJW73083.1 - 0.045 13.6 3.5 2.6 8.0 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CH PF00307.31 RJW73084.1 - 3.2e-24 85.2 0.9 1.1e-11 44.9 0.1 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW73084.1 - 0.0045 16.8 0.0 3.5 7.5 0.0 2.7 2 1 0 2 2 2 2 CAMSAP CH domain Med12-LCEWAV PF12145.8 RJW73084.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain FYVE PF01363.21 RJW73085.1 - 3.4e-22 78.4 33.0 7.7e-14 51.6 7.1 4.3 4 0 0 4 4 4 3 FYVE zinc finger GBP PF02263.19 RJW73085.1 - 6.2e-05 22.4 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 RJW73085.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RJW73085.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DUF87 PF01935.17 RJW73085.1 - 0.21 11.6 0.1 0.54 10.3 0.0 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain UAA PF08449.11 RJW73086.1 - 1.1e-64 218.6 14.5 1.5e-64 218.1 14.5 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RJW73086.1 - 0.0001 22.5 32.9 0.0044 17.2 15.8 3.0 3 1 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 RJW73086.1 - 0.00017 20.6 4.1 0.00017 20.6 4.1 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 RJW73086.1 - 0.0083 15.5 9.1 0.026 13.9 3.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family Beta-lactamase PF00144.24 RJW73087.1 - 1.6e-08 34.2 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase PDZ_6 PF17820.1 RJW73087.1 - 2.3e-05 24.1 0.0 5.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RJW73087.1 - 0.0024 18.2 0.0 0.0087 16.4 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RJW73087.1 - 0.027 14.8 0.0 0.079 13.3 0.0 1.7 1 0 0 1 1 1 0 PDZ domain zf-C2H2 PF00096.26 RJW73088.1 - 5.3e-14 51.8 21.0 1.4e-05 25.3 0.1 5.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW73088.1 - 6.3e-12 45.4 16.6 1.7e-05 25.0 0.5 4.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RJW73088.1 - 1.1e-06 29.0 21.0 0.0053 17.5 0.2 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW73088.1 - 1.9e-06 27.5 4.6 0.037 13.8 0.0 3.7 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-Di19 PF05605.12 RJW73088.1 - 0.012 15.9 3.0 6.1 7.2 2.1 2.9 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 RJW73088.1 - 0.12 12.2 14.2 0.1 12.4 0.6 4.4 4 1 0 4 4 4 0 C2H2-type zinc-finger domain zf-FPG_IleRS PF06827.14 RJW73088.1 - 0.14 12.0 5.2 0.6 10.0 2.2 2.9 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-met PF12874.7 RJW73088.1 - 0.16 12.4 7.9 3.3 8.2 0.0 4.4 4 1 0 4 4 4 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 RJW73088.1 - 0.16 12.6 0.3 2.3 8.9 0.1 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain Zn_Tnp_IS1595 PF12760.7 RJW73088.1 - 0.17 11.9 6.2 0.47 10.5 2.0 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-DBF PF07535.12 RJW73088.1 - 0.26 11.4 2.2 0.61 10.2 2.2 1.6 1 0 0 1 1 1 0 DBF zinc finger DZR PF12773.7 RJW73088.1 - 0.77 9.8 5.3 21 5.3 5.3 3.0 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_6 PF13912.6 RJW73088.1 - 1.1 9.3 14.6 1.5 8.9 0.0 4.4 3 1 0 3 3 3 0 C2H2-type zinc finger A2L_zn_ribbon PF08792.10 RJW73088.1 - 1.5 8.7 4.0 27 4.7 0.1 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain Zn_ribbon_SprT PF17283.2 RJW73088.1 - 1.8 8.6 9.8 0.25 11.3 0.3 3.2 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zf-BED PF02892.15 RJW73088.1 - 2.2 8.4 11.1 0.47 10.5 0.3 3.1 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_3 PF13878.6 RJW73088.1 - 2.9 7.8 8.0 1 9.3 0.1 3.1 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-CCHC_2 PF13696.6 RJW73088.1 - 8.1 6.4 7.0 5.1 7.0 1.2 2.6 2 0 0 2 2 2 0 Zinc knuckle DUF1681 PF07933.14 RJW73090.1 - 1.4e-53 180.6 0.0 1.7e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SIX1_SD PF16878.5 RJW73091.1 - 7.3e-41 139.2 0.6 2.4e-40 137.5 0.0 2.0 3 0 0 3 3 3 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 RJW73091.1 - 6.7e-16 57.9 1.3 1.8e-15 56.5 0.2 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RJW73091.1 - 1.4e-11 44.1 0.6 3.9e-11 42.7 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain CENP-B_N PF04218.13 RJW73091.1 - 0.0054 16.3 0.0 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain YdaS_antitoxin PF15943.5 RJW73091.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 RJW73091.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_28 PF13518.6 RJW73091.1 - 0.021 14.9 0.0 0.083 13.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 RJW73091.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF4154 PF13689.6 RJW73091.1 - 0.15 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 YfiR/HmsC-like SIX1_SD PF16878.5 RJW73092.1 - 7.9e-42 142.3 0.1 1.8e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 RJW73092.1 - 3.5e-12 46.0 0.8 8.5e-12 44.7 0.3 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RJW73092.1 - 1.5e-10 40.8 0.6 3.8e-10 39.5 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF3678 PF12435.8 RJW73092.1 - 6 6.3 7.7 22 4.5 7.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) MOZART2 PF12926.7 RJW73093.1 - 8e-07 28.6 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated HTH_20 PF12840.7 RJW73093.1 - 0.076 13.1 0.2 2.3 8.3 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain JHD PF17811.1 RJW73094.1 - 6.5e-18 65.2 0.1 1.4e-17 64.1 0.1 1.6 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 RJW73094.1 - 1.5e-12 47.9 0.1 3.3e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 RJW73094.1 - 1.8e-10 41.0 0.0 3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Band_7 PF01145.25 RJW73097.1 - 1.3e-32 113.2 2.7 1.7e-32 112.9 2.7 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 RJW73097.1 - 0.00099 18.9 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family SEP PF08059.13 RJW73098.1 - 5.8e-24 84.5 0.1 1.5e-23 83.2 0.0 1.7 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 RJW73098.1 - 2.4e-18 66.1 0.1 1.9e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 UBX domain Totivirus_coat PF05518.11 RJW73098.1 - 0.24 9.4 0.8 0.34 8.9 0.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein Branch PF02485.21 RJW73101.1 - 1.4e-21 77.1 0.0 2e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme HECW1_helix PF18436.1 RJW73101.1 - 0.1 12.8 0.4 6.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 DUF5564 PF17719.1 RJW73101.1 - 0.15 12.2 0.0 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5564) Tmemb_18A PF09771.9 RJW73103.1 - 6.4e-49 165.3 0.0 7.3e-49 165.1 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 DUF3989 PF13150.6 RJW73103.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) DUF417 PF04224.12 RJW73103.1 - 0.082 12.5 0.5 0.1 12.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF417 Clathrin PF00637.20 RJW73104.1 - 1.4e-49 167.6 3.0 7.2e-25 87.5 0.2 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS Clathrin_propel PF01394.20 RJW73104.1 - 2e-43 144.7 3.5 1.2e-09 37.9 0.0 6.5 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 RJW73104.1 - 2.8e-32 110.4 1.7 4.8e-32 109.7 0.7 2.0 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 RJW73104.1 - 3.7e-09 35.8 0.7 8.3e-09 34.6 0.2 1.9 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_19 PF14559.6 RJW73104.1 - 0.00067 20.1 0.5 2.7 8.6 0.5 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Peptidase_M16 PF00675.20 RJW73105.1 - 5.3e-53 179.0 0.0 3.3e-52 176.4 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RJW73105.1 - 5.9e-31 107.9 0.0 2.3e-29 102.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain zf-C3HC4_2 PF13923.6 RJW73106.1 - 2.1e-11 43.5 8.4 4.7e-11 42.3 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RJW73106.1 - 2.7e-09 36.7 8.4 6.9e-09 35.4 8.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW73106.1 - 9.2e-09 35.2 3.4 9.2e-09 35.2 3.4 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RJW73106.1 - 5e-08 32.7 10.3 8.7e-08 31.9 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RJW73106.1 - 5.1e-08 33.1 7.9 5.1e-08 33.1 7.9 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 RJW73106.1 - 9.9e-07 28.5 10.1 2e-06 27.6 10.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RJW73106.1 - 1.9e-06 27.9 11.0 4.8e-06 26.6 11.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RJW73106.1 - 5.4e-06 26.3 10.7 5.4e-06 26.3 10.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 RJW73106.1 - 0.0053 16.6 5.0 0.0097 15.8 5.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 RJW73106.1 - 0.029 14.6 6.8 0.029 14.6 6.8 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 RJW73106.1 - 0.088 12.6 6.9 0.24 11.2 6.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 RJW73106.1 - 0.45 10.7 7.8 1.3 9.3 7.8 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 RJW73106.1 - 0.49 10.2 7.1 1.1 9.2 7.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ZPR1 PF03367.13 RJW73107.1 - 0.049 13.5 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 ZPR1 zinc-finger domain UTP15_C PF09384.10 RJW73108.1 - 3.2e-14 52.9 0.6 1.5e-13 50.7 0.6 2.0 1 1 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 RJW73108.1 - 4.9e-11 43.0 1.1 0.00012 22.8 0.2 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73108.1 - 8.5e-08 32.4 0.0 0.0054 17.0 0.0 4.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RJW73108.1 - 0.00063 18.6 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Utp13 PF08625.11 RJW73108.1 - 0.0049 16.8 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Vasohibin PF14822.6 RJW73109.1 - 1.5e-13 50.6 0.0 2.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Vasohibin zf-RING_14 PF17978.1 RJW73112.1 - 3.3e-25 88.3 1.4 3.3e-25 88.3 1.4 3.7 4 1 0 4 4 4 1 RING/Ubox like zinc-binding domain IBR PF01485.21 RJW73112.1 - 1.2e-06 28.6 29.7 3.4e-05 24.0 19.4 5.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain ubiquitin PF00240.23 RJW73112.1 - 0.0023 17.6 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Ku PF02735.16 RJW73113.1 - 4.1e-40 137.7 0.0 5.7e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 RJW73113.1 - 6.9e-26 90.8 0.0 1.2e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like MBOAT PF03062.19 RJW73114.1 - 1.9e-16 60.4 12.3 4.3e-16 59.2 12.3 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Peptidase_M1 PF01433.20 RJW73116.1 - 0.078 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain TCTP PF00838.17 RJW73117.1 - 1.1e-54 185.3 1.8 1.3e-54 185.0 1.8 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein Kelch_1 PF01344.25 RJW73119.1 - 1.8e-84 277.1 17.3 2.1e-15 56.0 1.4 6.4 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 RJW73119.1 - 2e-35 121.0 0.1 4e-35 120.0 0.0 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 RJW73119.1 - 3.9e-34 115.8 7.2 2.6e-06 27.5 0.0 6.8 3 2 4 7 7 7 6 Kelch motif BTB PF00651.31 RJW73119.1 - 1.7e-30 105.5 0.9 2.7e-30 104.9 0.9 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 RJW73119.1 - 3.5e-23 80.6 6.0 0.00016 21.5 0.1 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RJW73119.1 - 8.7e-23 80.1 9.1 0.00012 22.0 0.0 6.3 5 2 2 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 RJW73119.1 - 4.1e-13 49.3 18.7 0.00075 19.7 0.0 7.5 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RJW73119.1 - 1.9e-05 24.6 8.1 0.82 9.7 0.1 5.4 5 0 0 5 5 5 2 Kelch motif Carn_acyltransf PF00755.20 RJW73120.1 - 3.8e-142 474.9 0.0 4.3e-142 474.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CENP-S PF15630.6 RJW73122.1 - 1.7e-23 82.8 0.6 2.9e-23 82.0 0.6 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 RJW73122.1 - 3.6e-08 33.5 0.2 6.1e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF1163 PF06651.11 RJW73122.1 - 0.011 15.8 0.7 0.029 14.4 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1163) CH PF00307.31 RJW73126.1 - 2.7e-43 146.6 0.4 2e-21 76.2 0.3 3.6 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RJW73126.1 - 7.5e-06 25.7 0.0 0.0033 17.2 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain TpcC PF12642.7 RJW73126.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Conjugative transposon protein TcpC SesA PF17107.5 RJW73126.1 - 0.074 13.2 13.1 0.49 10.6 0.0 5.5 4 1 1 5 5 5 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF5329 PF17263.2 RJW73126.1 - 0.11 12.7 4.4 5.3 7.3 0.0 4.6 4 0 0 4 4 4 0 Family of unknown function (DUF5329) DUF1664 PF07889.12 RJW73126.1 - 0.11 12.5 17.4 0.9 9.6 0.1 6.3 6 0 0 6 6 6 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 RJW73126.1 - 1.9 8.5 19.8 0.67 10.0 1.8 5.9 6 0 0 6 6 6 0 Laminin Domain II IKKbetaNEMObind PF12179.8 RJW73126.1 - 2 8.5 4.4 0.92 9.6 0.3 2.8 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain GAS PF13851.6 RJW73126.1 - 3.9 6.8 28.2 0.27 10.6 0.4 5.2 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding V-SNARE_C PF12352.8 RJW73128.1 - 1.7e-09 37.8 2.1 1.9e-09 37.7 0.6 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RJW73128.1 - 0.0015 18.4 2.8 0.0031 17.4 0.0 2.7 3 0 0 3 3 3 1 Sec20 MSC PF09402.10 RJW73128.1 - 0.046 13.2 0.1 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Metal_resist PF13801.6 RJW73128.1 - 0.45 10.7 7.1 0.39 10.9 0.2 2.7 3 0 0 3 3 3 0 Heavy-metal resistance Ribosomal_S8e PF01201.22 RJW73129.1 - 2.5e-44 150.7 0.6 2.9e-44 150.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e V-ATPase_G PF03179.15 RJW73130.1 - 4.8e-28 97.8 12.7 6.7e-28 97.3 12.7 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Sds3 PF08598.11 RJW73130.1 - 0.96 9.4 7.3 1.6 8.7 7.3 1.2 1 0 0 1 1 1 0 Sds3-like HPD PF05044.12 RJW73132.1 - 2.3e-78 261.4 4.4 3.8e-78 260.7 4.4 1.4 1 0 0 1 1 1 1 Homeo-prospero domain Nop PF01798.18 RJW73132.1 - 0.056 12.9 0.3 0.13 11.7 0.3 1.5 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Isy1 PF06246.12 RJW73133.1 - 5.1e-58 196.6 2.1 3.9e-53 180.6 0.5 2.1 2 0 0 2 2 2 2 Isy1-like splicing family DUF3741 PF12552.8 RJW73134.1 - 0.012 15.5 23.5 39 4.3 0.1 7.1 7 0 0 7 7 7 0 Protein of unknown function (DUF3741) Phage_fiber PF03335.13 RJW73134.1 - 0.12 12.6 32.7 43 4.7 0.3 7.6 7 0 0 7 7 7 0 Phage tail fibre repeat RRM_Rrp7 PF17799.1 RJW73134.1 - 1.8 8.3 4.0 1.2e+02 2.4 0.0 4.8 2 1 4 6 6 6 0 Rrp7 RRM-like N-terminal domain Mtp PF03821.16 RJW73135.1 - 9.3e-06 25.4 22.3 0.0013 18.4 1.8 3.4 3 1 1 4 4 4 3 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 RJW73135.1 - 0.034 14.8 13.6 0.034 14.8 13.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) OSTbeta PF15048.6 RJW73135.1 - 0.098 12.8 0.8 0.26 11.4 0.8 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein RVT_1 PF00078.27 RJW73136.1 - 5.1e-46 157.0 0.0 8.2e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 RJW73137.1 - 3.4e-12 46.3 8.9 4.4e-12 45.9 8.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RJW73137.1 - 6.9e-08 32.1 14.8 0.00014 21.3 2.6 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Frag1 PF10277.9 RJW73138.1 - 6.2e-09 35.7 10.8 7.9e-09 35.4 10.8 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF5463 PF17551.2 RJW73138.1 - 0.0052 16.7 0.1 0.017 15.0 0.1 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5463) DUF1820 PF08850.11 RJW73138.1 - 0.11 13.0 0.1 0.19 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) Ferric_reduct PF01794.19 RJW73138.1 - 0.16 12.1 8.7 0.56 10.3 8.0 2.3 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DSPc PF00782.20 RJW73139.1 - 1.4e-33 115.6 0.0 2.3e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 RJW73139.1 - 0.02 15.2 0.2 0.064 13.6 0.0 1.9 2 0 0 2 2 2 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 RJW73139.1 - 0.033 13.8 0.2 0.062 12.8 0.0 1.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Bromodomain PF00439.25 RJW73140.1 - 8.4e-12 45.0 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Calx-beta PF03160.14 RJW73141.1 - 2.1e-54 181.9 13.0 6.6e-30 103.2 1.0 3.0 4 0 0 4 4 4 2 Calx-beta domain Na_Ca_ex PF01699.24 RJW73141.1 - 4.2e-29 101.5 13.6 4.2e-29 101.5 13.6 1.5 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 RJW73141.1 - 3.3e-27 95.4 2.5 6.3e-27 94.5 2.5 1.4 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain LRR_8 PF13855.6 RJW73143.1 - 5e-52 173.5 72.7 4.1e-08 32.9 0.5 11.4 2 2 11 14 14 14 14 Leucine rich repeat LRR_4 PF12799.7 RJW73143.1 - 1.7e-39 133.2 74.4 3.1e-05 24.2 0.1 13.1 8 4 3 13 13 13 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW73143.1 - 2.4e-09 36.4 67.5 1.5 9.6 0.0 19.1 20 2 0 20 20 20 4 Leucine Rich Repeat LRR_5 PF13306.6 RJW73143.1 - 3.2e-05 23.9 4.6 0.57 10.2 0.1 4.4 3 1 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RJW73143.1 - 8.8e-05 22.1 27.6 0.3 10.6 0.0 6.0 2 1 4 6 6 6 5 Leucine-rich repeat RsmF_methylt_CI PF17126.5 RJW73143.1 - 0.085 12.9 5.3 34 4.6 0.0 6.1 6 2 3 9 9 9 0 RsmF rRNA methyltransferase first C-terminal domain RINGv PF12906.7 RJW73144.1 - 0.00037 20.5 1.8 0.00037 20.5 1.8 2.4 3 0 0 3 3 3 1 RING-variant domain Colicin_V PF02674.16 RJW73144.1 - 0.0036 17.3 0.1 0.0054 16.7 0.1 1.2 1 0 0 1 1 1 1 Colicin V production protein zf-RING_2 PF13639.6 RJW73144.1 - 0.022 15.1 1.4 0.11 12.8 0.2 2.6 2 0 0 2 2 2 0 Ring finger domain FtsX PF02687.21 RJW73144.1 - 0.025 15.0 4.8 0.039 14.4 4.8 1.2 1 0 0 1 1 1 0 FtsX-like permease family Sm_multidrug_ex PF06695.11 RJW73144.1 - 0.071 13.7 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative small multi-drug export protein DUF3021 PF11457.8 RJW73144.1 - 0.08 13.3 3.8 0.14 12.5 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF4233 PF14017.6 RJW73144.1 - 0.094 13.1 2.7 0.14 12.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) PHD PF00628.29 RJW73145.1 - 3.1e-35 119.8 90.8 1.3e-09 37.8 9.1 8.2 6 2 2 8 8 8 6 PHD-finger zf-HC5HC2H PF13771.6 RJW73145.1 - 2.1e-10 40.7 4.1 2.1e-10 40.7 4.1 7.5 5 3 2 8 8 8 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RJW73145.1 - 4.2e-07 30.1 7.9 4.2e-07 30.1 7.9 6.4 3 2 4 7 7 7 2 PHD-zinc-finger like domain PHD_2 PF13831.6 RJW73145.1 - 0.0019 17.7 1.8 0.0019 17.7 1.8 7.3 7 0 0 7 7 7 5 PHD-finger zf-C2H2_6 PF13912.6 RJW73145.1 - 0.64 10.1 3.2 4.9 7.3 0.2 3.8 2 0 0 2 2 2 0 C2H2-type zinc finger NADH-G_4Fe-4S_3 PF10588.9 RJW73145.1 - 1.7 8.2 7.5 1 9.0 0.1 4.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Siva PF05458.12 RJW73146.1 - 0.074 12.7 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) ANAPC10 PF03256.16 RJW73149.1 - 3.7e-34 118.0 0.0 4.3e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 RJW73149.1 - 0.017 15.2 0.0 0.022 14.9 0.0 1.1 1 0 0 1 1 1 0 F5/8 type C domain XRCC1_N PF01834.16 RJW73149.1 - 0.13 12.2 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 XRCC1 N terminal domain RGS_DHEX PF18148.1 RJW73149.1 - 0.15 12.2 0.0 3.9 7.7 0.0 2.0 1 1 1 2 2 2 0 Regulator of G-protein signalling DHEX domain CLTH PF10607.9 RJW73150.1 - 1.1e-15 57.8 0.3 2.3e-15 56.7 0.1 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain PSCyt3 PF07627.11 RJW73150.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) RabGAP-TBC PF00566.18 RJW73151.1 - 1.2e-30 106.7 2.4 1.4e-28 100.0 0.2 2.8 2 1 0 2 2 2 2 Rab-GTPase-TBC domain WD40 PF00400.32 RJW73153.1 - 4.1e-05 24.2 13.1 0.046 14.6 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_2 PF13360.6 RJW73153.1 - 0.0027 17.3 0.2 0.0082 15.7 0.1 1.9 2 0 0 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 RJW73153.1 - 0.018 15.3 0.0 0.96 9.8 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW73153.1 - 0.094 11.7 0.0 4.5 6.1 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RVT_1 PF00078.27 RJW73154.1 - 1.1e-16 61.1 0.0 1.2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AA_permease_2 PF13520.6 RJW73156.1 - 2.6e-62 211.0 52.6 3.1e-62 210.8 52.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RJW73156.1 - 2.2e-27 95.8 46.1 3e-27 95.4 46.1 1.2 1 0 0 1 1 1 1 Amino acid permease FragX_IP PF05994.11 RJW73157.1 - 0 1212.7 0.0 0 1212.7 0.0 1.7 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 RJW73157.1 - 1e-08 34.8 6.4 2.5e-08 33.5 6.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) SSP160 PF06933.11 RJW73157.1 - 8.4 4.4 11.4 13 3.9 11.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AA_permease_2 PF13520.6 RJW73158.1 - 8.7e-62 209.3 53.2 1.1e-61 209.0 53.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RJW73158.1 - 1.2e-28 100.0 46.5 1.7e-28 99.5 46.5 1.2 1 0 0 1 1 1 1 Amino acid permease Tetraspanin PF00335.20 RJW73159.1 - 4.8e-15 55.9 0.5 5.5e-15 55.7 0.5 1.0 1 0 0 1 1 1 1 Tetraspanin family tRNA-synt_2 PF00152.20 RJW73160.1 - 8.2e-32 110.5 0.0 8.7e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) AA_permease_2 PF13520.6 RJW73161.1 - 1.1e-59 202.3 50.5 1.4e-59 202.0 50.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RJW73161.1 - 1.2e-27 96.7 45.1 1.6e-27 96.2 45.1 1.2 1 0 0 1 1 1 1 Amino acid permease Kunitz_BPTI PF00014.23 RJW73164.1 - 7.4e-16 58.1 7.4 9e-16 57.9 7.4 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain CDK5_activator PF03261.15 RJW73166.1 - 4.6e-60 204.1 12.2 8.1e-48 163.8 7.7 2.9 2 1 0 2 2 2 2 Cyclin-dependent kinase 5 activator protein Ank_2 PF12796.7 RJW73167.1 - 2.2e-12 47.4 0.0 5.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW73167.1 - 2.9e-12 46.6 0.0 1.9e-07 31.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW73167.1 - 6.4e-10 39.4 0.0 1.9e-09 37.9 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW73167.1 - 1.4e-09 37.4 0.0 0.00062 20.0 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RJW73167.1 - 3.8e-09 36.6 0.0 0.0029 18.0 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeat AAA_9 PF12781.7 RJW73167.1 - 1.9e-05 23.9 0.0 1.9e-05 23.9 0.0 3.0 3 1 0 3 3 3 1 ATP-binding dynein motor region PEHE PF15275.6 RJW73167.1 - 0.0088 16.7 3.5 0.0088 16.7 3.5 2.5 2 1 1 3 3 3 1 PEHE domain T2SSM_b PF10741.9 RJW73167.1 - 0.089 12.6 0.0 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Acatn PF13000.7 RJW73168.1 - 5.8e-18 64.7 9.6 5.8e-18 64.7 9.6 2.6 2 1 0 2 2 2 1 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.16 RJW73168.1 - 1.6e-10 40.5 19.6 1.6e-10 40.5 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 RJW73168.1 - 4.2 7.9 5.5 2.5 8.6 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Gelsolin PF00626.22 RJW73170.1 - 4e-40 135.6 0.1 4.6e-14 52.1 0.1 3.3 3 0 0 3 3 3 3 Gelsolin repeat N_formyltrans_C PF18216.1 RJW73170.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain AA_permease_2 PF13520.6 RJW73171.1 - 9e-59 199.4 38.4 1.1e-58 199.1 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RJW73171.1 - 6.2e-24 84.4 34.3 8e-24 84.1 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 RJW73173.1 - 2e-10 40.1 15.9 1.3e-09 37.5 12.0 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RJW73173.1 - 7.9e-09 34.8 4.6 1e-08 34.5 4.6 1.2 1 0 0 1 1 1 1 MFS_1 like family ATG22 PF11700.8 RJW73173.1 - 0.019 13.6 6.9 0.28 9.8 6.9 2.1 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like DUF1218 PF06749.12 RJW73173.1 - 0.25 11.9 5.8 6.3 7.4 2.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) RRM_1 PF00076.22 RJW73174.1 - 3.7e-35 119.6 0.0 4e-17 61.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW73174.1 - 2.5e-07 30.7 0.3 0.0089 16.1 0.0 2.8 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RJW73174.1 - 0.02 14.9 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RVT_1 PF00078.27 RJW73175.1 - 2.5e-15 56.6 0.2 4.4e-15 55.8 0.2 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArgoMid PF16487.5 RJW73175.1 - 0.08 13.2 0.0 2.1 8.7 0.0 2.9 4 0 0 4 4 4 0 Mid domain of argonaute Glyco_hydro_20 PF00728.22 RJW73176.1 - 6.8e-122 407.3 0.3 3.9e-80 269.9 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 RJW73176.1 - 7.5e-10 39.6 0.0 1.8e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 RJW73176.1 - 3e-05 24.8 0.0 5.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Lipase_C PF18067.1 RJW73176.1 - 0.048 14.2 0.0 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Lipase C-terminal domain NCD1 PF04904.13 RJW73176.1 - 0.092 12.8 0.3 20 5.3 0.0 3.1 3 0 0 3 3 3 0 NAB conserved region 1 (NCD1) RVT_connect PF06815.13 RJW73176.1 - 7.8 6.8 7.8 9.1 6.6 0.9 3.1 3 0 0 3 3 3 0 Reverse transcriptase connection domain Ints3 PF10189.9 RJW73177.1 - 5e-76 254.9 1.8 5.2e-76 254.9 0.7 1.6 2 0 0 2 2 2 1 Integrator complex subunit 3 Kunitz_BPTI PF00014.23 RJW73179.1 - 5.2e-12 45.8 14.9 1e-05 25.7 8.5 2.4 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Peptidase_M28 PF04389.17 RJW73180.1 - 1.2e-38 132.8 0.0 5.2e-38 130.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 ER PF01133.17 RJW73180.1 - 1.2e-38 131.0 0.0 2.4e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 Enhancer of rudimentary Peptidase_M20 PF01546.28 RJW73180.1 - 0.076 12.7 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Myb_DNA-bind_5 PF13873.6 RJW73181.1 - 0.03 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF747 PF05346.11 RJW73182.1 - 1.6e-92 310.4 11.7 2.2e-92 310.0 11.7 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Gelsolin PF00626.22 RJW73183.1 - 3e-36 123.1 0.1 8.9e-14 51.2 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Amino_oxidase PF01593.24 RJW73185.1 - 6e-47 161.0 0.0 2.2e-46 159.1 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RJW73185.1 - 1e-16 60.9 0.1 2.5e-16 59.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RJW73185.1 - 1e-08 34.7 0.2 1.8e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 RJW73185.1 - 3.6e-07 29.6 2.1 5.3e-07 29.1 2.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 RJW73185.1 - 3.4e-06 26.5 1.0 5.3e-06 25.9 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 RJW73185.1 - 6.7e-06 25.9 2.9 1.3e-05 25.0 2.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 RJW73185.1 - 8.6e-06 25.3 1.8 1.3e-05 24.8 1.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RJW73185.1 - 1.6e-05 23.8 0.4 2.5e-05 23.2 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 RJW73185.1 - 1.7e-05 24.2 0.2 2.6e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RJW73185.1 - 0.00035 19.8 0.5 0.00053 19.2 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 RJW73185.1 - 0.0012 19.4 1.5 0.0024 18.4 1.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RJW73185.1 - 0.0021 17.2 1.3 0.0053 15.9 0.3 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 RJW73185.1 - 0.0025 17.1 0.3 0.0042 16.4 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 RJW73185.1 - 0.015 14.6 0.8 0.027 13.7 0.8 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RJW73185.1 - 0.047 12.5 1.0 0.067 12.0 1.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FMO-like PF00743.19 RJW73185.1 - 0.25 9.7 0.0 0.35 9.2 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.18 RJW73185.1 - 0.26 11.1 0.6 0.46 10.3 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.32 RJW73186.1 - 5.1e-23 80.9 6.5 0.00053 20.7 0.0 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 RJW73186.1 - 0.00014 20.7 1.6 0.58 8.7 0.1 3.3 3 0 0 3 3 3 2 Nucleoporin Nup120/160 TSP_1 PF00090.19 RJW73187.1 - 0.00044 20.4 8.0 0.0025 18.0 8.0 2.4 1 0 0 1 1 1 1 Thrombospondin type 1 domain hEGF PF12661.7 RJW73187.1 - 0.0029 18.2 25.2 0.47 11.2 1.0 5.3 4 0 0 4 4 4 3 Human growth factor-like EGF RVT_1 PF00078.27 RJW73188.1 - 0.0003 20.4 0.0 0.0044 16.6 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2599 PF10783.9 RJW73188.1 - 0.029 15.0 0.5 3.6 8.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2599) PolyA_pol_RNAbd PF12627.7 RJW73188.1 - 0.051 13.3 0.0 0.42 10.4 0.0 2.3 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A CN_hydrolase PF00795.22 RJW73189.1 - 1.6e-15 57.2 0.0 1.8e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Otopetrin PF03189.13 RJW73191.1 - 1.6e-84 284.3 4.5 1.6e-84 284.3 4.5 2.3 2 1 0 2 2 2 1 Otopetrin DUF5617 PF18493.1 RJW73191.1 - 0.12 12.5 1.5 0.82 9.8 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) TMA7 PF09072.10 RJW73192.1 - 6.9e-20 71.6 19.8 9.5e-20 71.2 19.8 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 RVT_1 PF00078.27 RJW73192.1 - 1.9e-05 24.3 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mucin PF01456.17 RJW73193.1 - 0.5 10.4 25.6 1.3 9.1 25.6 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 RJW73193.1 - 2.6 6.1 6.9 3.9 5.5 6.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 RJW73193.1 - 4.5 5.1 4.6 7.1 4.5 4.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAN_1 PF00024.26 RJW73194.1 - 0.062 13.3 3.8 0.25 11.3 1.3 2.4 2 0 0 2 2 2 0 PAN domain RPN7 PF10602.9 RJW73196.1 - 1.4e-40 138.8 0.0 3.3e-40 137.6 0.0 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 RJW73196.1 - 5.6e-14 52.5 0.2 2.7e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 PCI domain BORCS7 PF16088.5 RJW73196.1 - 0.0082 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 TPR_8 PF13181.6 RJW73196.1 - 0.011 15.9 0.1 0.031 14.5 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 RJW73196.1 - 0.035 14.2 0.2 0.15 12.3 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW73196.1 - 0.077 12.8 0.2 0.21 11.5 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat BAH PF01426.18 RJW73197.1 - 1.2e-09 38.1 0.0 6.9e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 BAH domain RT_RNaseH_2 PF17919.1 RJW73200.1 - 0.0017 18.3 0.0 0.65 10.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase eRF1_2 PF03464.15 RJW73200.1 - 0.091 13.1 0.0 14 6.0 0.0 2.3 2 0 0 2 2 2 0 eRF1 domain 2 SDF PF00375.18 RJW73201.1 - 7.1e-128 426.9 25.2 8.4e-128 426.7 25.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Mpp10 PF04006.12 RJW73202.1 - 0.064 11.7 12.1 0.088 11.2 12.1 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RJW73202.1 - 1.4 8.3 22.9 2.3 7.6 22.9 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RJW73202.1 - 2.5 6.2 24.0 3.3 5.8 24.0 1.1 1 0 0 1 1 1 0 Nop14-like family EGF_2 PF07974.13 RJW73203.1 - 0.013 15.9 6.6 0.013 15.9 6.6 4.7 4 1 0 4 4 4 0 EGF-like domain EGF PF00008.27 RJW73203.1 - 0.13 12.6 42.9 0.043 14.1 4.7 5.4 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.7 RJW73203.1 - 8.4 7.2 27.4 2.3 9.0 2.4 5.8 5 0 0 5 5 5 0 Human growth factor-like EGF Asp_protease_2 PF13650.6 RJW73204.1 - 0.024 15.2 0.0 0.059 14.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 RJW73204.1 - 0.076 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Y_phosphatase PF00102.27 RJW73207.1 - 1.9e-32 112.8 0.1 3.1e-32 112.0 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 RJW73207.1 - 6.1e-12 45.7 6.2 0.32 11.4 0.0 7.0 8 0 0 8 8 8 5 Fibronectin type III domain Glyco_hydro_36C PF16874.5 RJW73207.1 - 0.0026 18.2 0.0 12 6.5 0.0 3.9 4 0 0 4 4 4 2 Glycosyl hydrolase family 36 C-terminal domain Bud13 PF09736.9 RJW73208.1 - 5.2e-42 143.7 10.1 8.2e-42 143.0 10.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Spore_III_AB PF09548.10 RJW73208.1 - 0.68 10.0 2.7 1.2 9.3 2.7 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) GCS PF03074.16 RJW73208.1 - 2 7.7 6.3 0.99 8.7 3.5 1.7 2 0 0 2 2 2 0 Glutamate-cysteine ligase Claudin_2 PF13903.6 RJW73210.1 - 6.7e-06 26.0 4.9 6.7e-06 26.0 4.9 2.3 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction SP_C-Propep PF08999.10 RJW73210.1 - 0.0014 18.4 1.4 0.062 13.1 0.1 2.5 3 0 0 3 3 3 1 Surfactant protein C, N terminal propeptide Peptidase_U4 PF03419.13 RJW73210.1 - 0.0022 17.3 1.0 0.0033 16.8 1.0 1.2 1 0 0 1 1 1 1 Sporulation factor SpoIIGA Amastin PF07344.11 RJW73210.1 - 0.0073 16.2 4.2 0.035 14.0 0.5 2.3 2 1 0 2 2 2 1 Amastin surface glycoprotein Saf_2TM PF18303.1 RJW73210.1 - 0.074 12.6 0.2 0.074 12.6 0.2 2.9 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain PMP22_Claudin PF00822.20 RJW73210.1 - 0.12 12.2 6.7 0.74 9.7 0.1 3.0 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family SAYSvFN PF10260.9 RJW73210.1 - 0.14 12.1 2.1 0.42 10.6 0.2 2.7 2 1 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DUF3262 PF11660.8 RJW73210.1 - 0.39 11.1 13.0 0.6 10.5 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3262) DUF4064 PF13273.6 RJW73210.1 - 0.54 10.6 9.5 1.8 8.9 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF3671 PF12420.8 RJW73210.1 - 1.3 9.2 5.3 1 9.5 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF2207 PF09972.9 RJW73210.1 - 3.6 6.3 6.2 7 5.3 2.3 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) RNA_pol_Rpc34 PF05158.12 RJW73213.1 - 6.3e-49 167.1 0.1 1.3e-48 166.2 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit FUR PF01475.19 RJW73213.1 - 0.00054 20.1 0.2 0.099 12.8 0.0 3.6 2 1 2 4 4 4 1 Ferric uptake regulator family TrmB PF01978.19 RJW73213.1 - 0.0012 18.7 0.7 0.042 13.7 0.1 3.3 3 1 1 4 4 4 1 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 RJW73213.1 - 0.0051 16.7 0.2 3.9 7.5 0.0 3.1 3 1 1 4 4 4 2 Transcriptional regulator PadR-like family ATP-cone PF03477.16 RJW73213.1 - 0.024 15.2 0.4 0.11 13.1 0.1 2.1 2 0 0 2 2 2 0 ATP cone domain Dala_Dala_lig_N PF01820.21 RJW73213.1 - 0.15 12.5 0.0 0.61 10.6 0.0 2.0 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus FIBP PF05427.11 RJW73214.1 - 1.6e-95 320.4 0.9 2e-95 320.2 0.9 1.0 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) Dynein_light PF01221.18 RJW73215.1 - 2e-26 92.1 0.0 2.4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Swm2 PF17083.5 RJW73215.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Nucleolar protein Swm2 Beach PF02138.18 RJW73217.1 - 1.5e-34 119.6 0.0 1.8e-22 80.1 0.0 2.3 2 0 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.32 RJW73217.1 - 2e-06 28.4 4.8 0.27 12.2 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Rotamase_3 PF13616.6 RJW73219.1 - 1.8e-18 67.2 0.0 4.5e-18 65.9 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 RJW73219.1 - 1.1e-14 55.2 0.0 2e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 RJW73219.1 - 0.0066 17.3 0.0 0.0098 16.7 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain VasL PF12486.8 RJW73220.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 Type VI secretion system, EvfB, or VasL MMR_HSR1 PF01926.23 RJW73221.1 - 1.5e-17 63.7 0.0 7.4e-14 51.8 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase NGP1NT PF08153.12 RJW73221.1 - 7.2e-09 35.9 0.1 1.4e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain FeoB_N PF02421.18 RJW73221.1 - 1.2e-05 24.9 0.0 2.8e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RJW73221.1 - 4.2e-05 23.5 0.0 0.00017 21.5 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 RJW73221.1 - 5.4e-05 23.3 0.1 0.95 9.5 0.0 3.3 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 RJW73221.1 - 0.00064 19.3 0.0 0.089 12.3 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 RJW73221.1 - 0.0023 17.4 0.1 0.86 9.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 RJW73221.1 - 0.035 14.3 0.1 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RJW73221.1 - 0.084 13.3 0.5 3 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 RJW73221.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain PDZ PF00595.24 RJW73222.1 - 2e-14 53.7 0.1 4.3e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RJW73222.1 - 3.8e-13 49.1 0.8 1.2e-09 37.9 0.1 2.7 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 RJW73222.1 - 3.8e-05 23.9 0.0 0.0069 16.7 0.0 2.6 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 RJW73222.1 - 0.05 13.6 0.1 0.92 9.5 0.1 2.3 2 0 0 2 2 2 0 Tricorn protease PDZ domain CO_deh_flav_C PF03450.17 RJW73226.1 - 0.027 14.7 0.1 0.032 14.4 0.1 1.1 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain Carb_anhydrase PF00194.21 RJW73227.1 - 3.3e-45 154.6 0.0 3.7e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase ubiquitin PF00240.23 RJW73229.1 - 2e-34 117.2 0.4 2.6e-34 116.8 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 RJW73229.1 - 1.4e-30 104.9 12.4 2.2e-30 104.3 12.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 RJW73229.1 - 1.6e-16 59.9 0.5 2.6e-16 59.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RJW73229.1 - 1.6e-05 25.3 0.1 6.5e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 RJW73229.1 - 0.0032 17.8 0.1 0.0053 17.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 RJW73229.1 - 0.0052 16.7 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 RJW73229.1 - 0.007 16.5 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 RJW73229.1 - 0.015 15.3 1.2 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 RJW73229.1 - 0.027 15.0 0.0 0.033 14.8 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain EF-hand_6 PF13405.6 RJW73230.1 - 1.2e-05 24.9 0.1 4.1e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 RJW73230.1 - 0.00039 20.8 0.0 0.00056 20.3 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW73230.1 - 0.00052 19.4 0.1 0.00052 19.4 0.1 2.0 3 0 0 3 3 3 1 EF hand DUF1160 PF06648.11 RJW73233.1 - 0.079 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) PXB PF12828.7 RJW73234.1 - 0.099 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 PX-associated HCR PF07111.12 RJW73235.1 - 1.8e-05 23.1 41.8 3e-05 22.4 41.8 1.3 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) Lebercilin PF15619.6 RJW73235.1 - 0.00078 19.2 15.0 0.00078 19.2 15.0 4.1 2 1 2 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 RJW73235.1 - 0.0061 16.2 12.2 0.0061 16.2 12.2 3.4 2 1 0 2 2 2 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 RJW73235.1 - 1.7 8.7 53.9 0.7 10.0 4.3 4.9 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein Scaffolding_pro PF11418.8 RJW73235.1 - 2 9.0 7.4 2.7 8.6 0.2 3.2 3 0 0 3 3 3 0 Phi29 scaffolding protein DUF916 PF06030.12 RJW73235.1 - 7.1 6.7 6.4 1.6 8.8 0.2 2.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF916) Histone PF00125.24 RJW73237.1 - 6.2e-23 81.6 1.4 7.8e-23 81.3 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RJW73237.1 - 3.2e-06 27.3 0.0 8.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RJW73237.1 - 0.00098 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RJW73237.1 - 0.0026 17.8 0.5 0.003 17.6 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein CNDH2_C PF16858.5 RJW73237.1 - 0.0031 17.5 0.4 0.0033 17.4 0.4 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term RVT_1 PF00078.27 RJW73239.1 - 0.022 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Miff PF05644.11 RJW73243.1 - 2.5e-11 43.8 6.0 6e-11 42.5 5.7 1.6 1 1 1 2 2 2 1 Mitochondrial and peroxisomal fission factor Mff Pro_isomerase PF00160.21 RJW73245.1 - 2.4e-35 122.1 0.1 3.9e-35 121.4 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 RJW73245.1 - 1.3e-16 60.2 0.1 3e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_9 PF08221.11 RJW73245.1 - 0.074 13.2 0.1 0.3 11.2 0.1 2.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Pkinase PF00069.25 RJW73247.1 - 6.7e-105 350.2 0.0 2.1e-74 250.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW73247.1 - 9.8e-55 185.6 0.0 9.4e-36 123.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RJW73247.1 - 8.9e-06 25.2 0.0 0.0033 16.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.9 RJW73247.1 - 0.00021 20.9 0.0 0.00043 19.9 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 RJW73247.1 - 0.00026 20.4 0.0 0.00059 19.2 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 RJW73247.1 - 0.00039 21.1 3.7 0.00052 20.7 0.8 2.6 3 0 0 3 3 3 1 Protein kinase C terminal domain APH PF01636.23 RJW73247.1 - 0.00054 20.0 0.1 0.34 10.8 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RJW73247.1 - 0.00061 18.7 0.1 0.051 12.4 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase RIO1 PF01163.22 RJW73247.1 - 0.0022 17.6 0.1 0.0037 16.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 RJW73249.1 - 1.6e-13 50.6 0.1 8.2e-06 25.3 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 RJW73249.1 - 1.8e-13 50.5 0.0 9.4e-06 25.2 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain LRR_4 PF12799.7 RJW73250.1 - 3.5e-14 52.7 15.1 2e-06 28.1 3.7 4.5 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW73250.1 - 3.4e-13 49.5 5.0 1.3e-12 47.6 4.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RJW73250.1 - 2.9e-08 33.3 15.7 4.3e-05 23.2 7.1 3.6 2 1 1 3 3 3 2 Leucine rich repeat Nod1 PF17114.5 RJW73250.1 - 0.15 12.2 4.7 0.22 11.7 1.8 2.5 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 LRR_6 PF13516.6 RJW73250.1 - 1.1 9.5 8.7 3.9 7.8 0.2 3.8 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 RJW73250.1 - 2.7 8.9 13.4 1.1e+02 4.0 2.3 5.4 4 1 0 4 4 4 0 Leucine Rich Repeat RTC PF01137.21 RJW73251.1 - 8.6e-38 129.7 0.0 1.2e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 RJW73251.1 - 1.3e-29 102.7 0.1 3.1e-29 101.5 0.0 1.7 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain ABC_tran PF00005.27 RJW73255.1 - 6.5e-55 185.4 0.0 4.8e-29 101.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RJW73255.1 - 1.4e-47 162.5 40.4 9.7e-29 100.5 8.9 2.7 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 RJW73255.1 - 1.4e-20 74.3 0.7 5.2e-06 26.5 0.1 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RJW73255.1 - 6.5e-05 23.5 0.9 0.03 14.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 RJW73255.1 - 0.00062 19.3 0.0 4.1 6.8 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 RJW73255.1 - 0.0082 15.4 0.0 1.9 7.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 RJW73255.1 - 0.0098 15.6 1.8 0.16 11.8 0.7 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 RJW73255.1 - 0.019 14.7 0.2 0.73 9.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RJW73255.1 - 0.021 14.8 0.0 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 RJW73255.1 - 0.022 14.9 0.5 4.6 7.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 RJW73255.1 - 0.029 14.0 2.1 1 9.0 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 RJW73255.1 - 0.071 13.4 2.1 4.9 7.4 1.0 3.3 2 1 0 2 2 2 0 AAA domain DUF4079 PF13301.6 RJW73255.1 - 0.55 10.4 6.9 7.5 6.7 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) 2-oxoacid_dh PF00198.23 RJW73257.1 - 3.8e-80 268.7 0.0 4.8e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RJW73257.1 - 4.1e-18 65.0 0.9 8.1e-18 64.0 0.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RJW73257.1 - 6.9e-05 22.6 0.1 0.002 17.9 0.0 2.8 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 RJW73257.1 - 0.0041 16.4 0.3 0.0074 15.5 0.0 1.6 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 RJW73257.1 - 0.011 15.7 0.3 0.066 13.2 0.0 2.1 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 RJW73257.1 - 0.048 13.6 0.3 0.13 12.1 0.1 1.8 1 1 1 2 2 2 0 Glycine cleavage H-protein Cnd1 PF12717.7 RJW73258.1 - 0.096 12.7 0.0 0.44 10.6 0.0 2.1 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 PEMT PF04191.13 RJW73258.1 - 0.19 12.1 0.0 0.45 10.9 0.0 1.5 1 0 0 1 1 1 0 Phospholipid methyltransferase VWA PF00092.28 RJW73260.1 - 6.3e-07 29.8 0.0 9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RJW73260.1 - 6.1e-06 26.8 0.1 1.1e-05 26.1 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain SIR2 PF02146.17 RJW73261.1 - 1.1e-53 181.8 0.0 1.3e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family AAA_18 PF13238.6 RJW73262.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RJW73262.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATG16 PF08614.11 RJW73262.1 - 0.22 11.8 12.7 1.2 9.3 12.7 2.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Swi5 PF07061.11 RJW73262.1 - 0.36 10.9 3.4 1.1 9.4 3.4 1.9 1 0 0 1 1 1 0 Swi5 DUF4407 PF14362.6 RJW73262.1 - 4.9 6.4 10.8 9 5.6 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GTP_EFTU PF00009.27 RJW73263.1 - 8.4e-56 188.6 0.0 1.7e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ribosomal_S7 PF00177.21 RJW73263.1 - 3.6e-24 85.1 0.9 7.8e-24 84.0 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e EFG_II PF14492.6 RJW73263.1 - 1.5e-22 79.5 0.0 3e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 RJW73263.1 - 1.5e-09 38.1 0.0 3.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RJW73263.1 - 3.6e-06 26.8 0.0 7.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain RVT_1 PF00078.27 RJW73263.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AvrPtoB_bdg PF16847.5 RJW73263.1 - 0.12 12.9 0.2 0.83 10.2 0.1 2.5 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain RVT_1 PF00078.27 RJW73265.1 - 1.2e-92 309.4 0.0 1.4e-45 155.5 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Jnk-SapK_ap_N PF09744.9 RJW73265.1 - 4.2e-36 124.5 9.6 4.2e-36 124.5 9.6 2.5 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 Exo_endo_phos_2 PF14529.6 RJW73265.1 - 2e-20 72.8 0.0 8.8e-11 41.7 0.0 3.5 4 0 0 4 4 4 2 Endonuclease-reverse transcriptase RILP PF11461.8 RJW73265.1 - 1.2e-13 51.1 0.1 4.5e-13 49.2 0.1 2.1 1 0 0 1 1 1 1 Rab interacting lysosomal protein Exo_endo_phos PF03372.23 RJW73265.1 - 5.6e-07 29.3 4.2 3.5e-06 26.7 0.4 2.9 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family XPC-binding PF09280.11 RJW73265.1 - 0.41 10.4 2.8 0.58 9.9 0.2 2.7 3 0 0 3 3 3 0 XPC-binding domain Bap31_Bap29_C PF18035.1 RJW73265.1 - 2.3 8.3 5.1 0.36 10.9 0.4 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain ATG16 PF08614.11 RJW73265.1 - 6.8 6.9 29.8 29 4.8 24.7 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) GSHPx PF00255.19 RJW73267.1 - 2.1e-21 75.5 0.0 2.6e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Thymidylate_kin PF02223.17 RJW73268.1 - 1.7e-20 73.5 0.0 2.2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase SH2_2 PF14633.6 RJW73269.1 - 5.3e-74 248.3 0.0 1.2e-73 247.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 RJW73269.1 - 3.2e-31 107.8 0.0 1.1e-30 106.1 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 RJW73269.1 - 4.6e-27 94.6 0.0 9.4e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 RJW73269.1 - 1.4e-16 60.9 2.1 3.3e-16 59.8 2.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_9 PF17674.1 RJW73269.1 - 5.2e-09 36.9 1.1 1.5e-08 35.4 1.1 1.9 1 0 0 1 1 1 1 HHH domain Tex_N PF09371.10 RJW73269.1 - 7.6e-08 32.2 0.0 0.0033 17.1 0.0 2.8 2 0 0 2 2 2 2 Tex-like protein N-terminal domain SH2 PF00017.24 RJW73269.1 - 3.2e-05 23.9 0.0 9.7e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 RJW73269.1 - 0.03 14.6 0.0 0.11 12.8 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif Tex_YqgF PF16921.5 RJW73269.1 - 0.051 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Tex protein YqgF-like domain S1 PF00575.23 RJW73269.1 - 0.13 12.7 0.0 0.6 10.5 0.0 2.2 2 0 0 2 2 2 0 S1 RNA binding domain LSM PF01423.22 RJW73270.1 - 1.6e-13 50.2 0.0 3.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 LSM domain RVT_1 PF00078.27 RJW73272.1 - 2.4e-48 164.6 1.0 8.7e-46 156.2 0.0 3.6 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMR_HSR1_Xtn PF16897.5 RJW73272.1 - 5.6e-35 119.6 0.3 1.6e-34 118.1 0.3 1.8 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 RJW73272.1 - 1.2e-20 73.7 0.0 2.9e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 RJW73272.1 - 1e-19 70.3 0.0 3.9e-19 68.4 0.1 2.0 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 RJW73272.1 - 1.1e-11 44.5 0.0 2.3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RJW73272.1 - 0.0077 16.3 0.5 0.66 10.0 0.5 2.6 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 RJW73272.1 - 0.06 13.2 0.3 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 RJW73272.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 RJW73273.1 - 2.7e-41 141.5 0.0 7.7e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW73273.1 - 3.8e-07 30.0 0.0 9.3e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW73273.1 - 0.0028 17.2 0.1 0.0091 15.5 0.1 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PEPCK_GTP PF00821.18 RJW73275.1 - 1.2e-162 540.8 0.0 1.6e-162 540.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 RJW73275.1 - 1.3e-89 299.6 0.0 1.7e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain HlyIII PF03006.20 RJW73278.1 - 3.7e-66 223.1 22.8 5.2e-66 222.6 22.8 1.2 1 0 0 1 1 1 1 Haemolysin-III related ToxB_N PF18224.1 RJW73279.1 - 0.025 14.5 0.3 0.059 13.3 0.0 1.7 2 0 0 2 2 2 0 ToxB N-terminal domain TFCD_C PF12612.8 RJW73280.1 - 7.4e-56 189.0 0.0 1.1e-54 185.2 0.0 2.8 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal RVT_1 PF00078.27 RJW73280.1 - 3e-15 56.3 0.0 5.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT PF02985.22 RJW73280.1 - 1.1e-05 25.2 10.6 0.87 10.0 0.0 7.4 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 RJW73280.1 - 7e-05 23.1 3.5 0.0072 16.7 0.1 4.7 5 0 0 5 5 5 1 HEAT repeats TAF6_C PF07571.13 RJW73280.1 - 0.00089 19.5 1.2 4.4 7.7 0.0 5.1 5 2 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 RJW73280.1 - 0.0042 17.6 10.4 3.3 8.3 0.1 6.3 5 1 1 6 6 6 2 HEAT-like repeat HEAT_PBS PF03130.16 RJW73280.1 - 3.9 8.4 9.5 0.62 10.9 0.1 4.2 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat LSM PF01423.22 RJW73281.1 - 0.0004 20.0 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF3528 PF12045.8 RJW73281.1 - 0.18 12.4 0.0 0.21 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3528) zf-NOSIP PF15906.5 RJW73282.1 - 0.0047 17.0 0.1 6.8 6.9 0.0 2.8 3 0 0 3 3 3 2 Zinc-finger of nitric oxide synthase-interacting protein Serinc PF03348.15 RJW73283.1 - 3.1e-62 210.9 4.0 4.2e-62 210.5 4.0 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF1129 PF06570.11 RJW73283.1 - 0.43 10.0 5.8 0.87 9.0 2.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) Tmem26 PF09772.9 RJW73285.1 - 6.8e-15 55.2 2.2 1.1e-14 54.5 2.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 26 V-SNARE_C PF12352.8 RJW73286.1 - 0.00032 20.9 9.5 0.059 13.7 1.1 2.6 2 1 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 RJW73286.1 - 0.00033 20.6 4.0 0.49 10.2 0.2 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF5089) Nup88 PF10168.9 RJW73286.1 - 0.0052 14.7 0.7 0.0052 14.7 0.7 1.5 2 0 0 2 2 2 1 Nuclear pore component SlyX PF04102.12 RJW73286.1 - 0.018 15.6 4.0 8.8 7.0 0.0 3.1 3 1 0 3 3 3 0 SlyX DUF16 PF01519.16 RJW73286.1 - 0.098 13.2 1.8 0.67 10.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 HemX PF04375.14 RJW73286.1 - 0.11 11.7 6.4 0.68 9.2 1.2 2.0 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase NPV_P10 PF05531.12 RJW73286.1 - 0.15 12.6 1.9 0.77 10.3 0.2 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 RJW73286.1 - 0.38 11.0 2.4 5.2 7.4 0.2 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Tho2 PF11262.8 RJW73286.1 - 1 8.5 3.0 1.6 7.9 0.2 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 UPF0242 PF06785.11 RJW73286.1 - 1.7 8.7 7.8 0.28 11.3 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YlqD PF11068.8 RJW73286.1 - 2.1 8.7 7.6 2.6 8.4 0.7 2.2 2 0 0 2 2 2 0 YlqD protein Histone PF00125.24 RJW73287.1 - 6.2e-23 81.6 1.4 7.8e-23 81.3 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RJW73287.1 - 3.2e-06 27.3 0.0 8.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RJW73287.1 - 0.00098 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RJW73287.1 - 0.0026 17.8 0.5 0.003 17.6 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein CNDH2_C PF16858.5 RJW73287.1 - 0.0031 17.5 0.4 0.0033 17.4 0.4 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_topoisoIV PF00521.20 RJW73288.1 - 7.4e-127 423.8 0.0 1.3e-126 422.9 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 RJW73288.1 - 9.8e-47 158.4 1.6 3.7e-46 156.6 1.6 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 RJW73288.1 - 2e-25 89.3 0.3 4.1e-25 88.2 0.3 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 RJW73288.1 - 6.8e-14 52.3 0.0 2.1e-13 50.8 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 RJW73288.1 - 3.5e-08 33.6 0.0 1.2e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Piezo_RRas_bdg PF12166.8 RJW73289.1 - 4.9e-117 391.8 0.3 8.5e-117 391.0 0.3 1.4 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain PIEZO PF15917.5 RJW73289.1 - 2e-29 102.7 5.3 6.3e-24 84.7 2.8 2.4 1 1 1 2 2 2 2 Piezo WD40 PF00400.32 RJW73290.1 - 8.7e-10 39.1 1.6 0.0031 18.3 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 RJW73290.1 - 0.027 13.1 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Zip PF02535.22 RJW73291.1 - 5.9e-15 55.3 9.8 5.2e-08 32.5 5.5 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter LRR_4 PF12799.7 RJW73292.1 - 5.2e-32 109.4 42.9 9.1e-07 29.1 1.3 7.4 7 0 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW73292.1 - 1.7e-22 79.7 21.2 2.1e-08 33.9 2.9 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 RJW73292.1 - 1.7e-17 62.9 66.2 1.6e-06 27.8 5.5 6.5 2 1 6 9 9 9 7 Leucine rich repeat LRR_6 PF13516.6 RJW73292.1 - 0.031 14.3 23.9 4.6 7.5 0.0 8.7 10 0 0 10 10 10 0 Leucine Rich repeat LRR_1 PF00560.33 RJW73292.1 - 0.16 12.6 35.5 15 6.6 0.0 9.6 9 3 0 9 9 9 0 Leucine Rich Repeat DUF2322 PF10084.9 RJW73292.1 - 1.7 8.7 4.2 40 4.3 0.1 3.8 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) Dus PF01207.17 RJW73293.1 - 2.2e-62 211.0 0.2 5.5e-62 209.6 0.2 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 RJW73293.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase IMPDH PF00478.25 RJW73293.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain SOR_SNZ PF01680.17 RJW73293.1 - 0.12 12.2 0.1 0.36 10.6 0.0 1.8 1 1 1 2 2 2 0 SOR/SNZ family zf-C2HCIx2C PF10782.9 RJW73293.1 - 1.1 9.2 5.8 0.86 9.6 3.0 2.2 2 0 0 2 2 2 0 Zinc-finger SURF2 PF05477.11 RJW73295.1 - 1e-24 87.5 0.7 1.5e-24 87.0 0.7 1.2 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) SLC35F PF06027.12 RJW73297.1 - 1.1e-46 159.7 28.4 1.3e-45 156.2 28.4 2.1 1 1 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 RJW73297.1 - 2.5e-07 30.0 1.5 2.5e-07 30.0 1.5 2.0 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 RJW73297.1 - 7.6e-05 22.9 30.1 0.00047 20.3 0.8 2.6 3 0 0 3 3 3 2 EamA-like transporter family Phage_holin_3_6 PF07332.11 RJW73297.1 - 0.31 11.1 0.1 0.31 11.1 0.1 3.5 3 2 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III PLRV_ORF5 PF01690.17 RJW73298.1 - 0.1 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Cyclin_N PF00134.23 RJW73299.1 - 1e-10 41.4 1.7 6.4e-06 25.9 0.5 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 RJW73299.1 - 0.004 17.2 0.2 1.6 8.8 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Troponin PF00992.20 RJW73300.1 - 0.0015 18.9 2.7 0.0015 18.9 2.7 2.4 2 0 0 2 2 2 1 Troponin GAGA_bind PF06217.12 RJW73300.1 - 0.31 11.3 10.4 0.4 10.9 10.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.16 RJW73300.1 - 8.8 6.3 5.7 11 6.0 5.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TERB2 PF15101.6 RJW73300.1 - 9 6.3 10.8 1.3 9.0 6.1 1.8 1 1 1 2 2 2 0 Telomere-associated protein TERB2 UCH PF00443.29 RJW73301.1 - 1.9e-33 116.1 0.0 1.9e-33 116.1 0.0 1.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RJW73301.1 - 6e-06 26.5 0.1 1.4e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 RJW73301.1 - 0.00088 18.9 0.3 0.0017 18.0 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pentaxin PF00354.17 RJW73302.1 - 0.014 15.1 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Pentaxin family RCC1 PF00415.18 RJW73303.1 - 2.8e-52 175.1 17.1 2.4e-08 34.5 0.0 9.4 8 2 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RJW73303.1 - 4.4e-18 64.6 35.1 9.5e-05 22.1 0.1 7.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat HEAT PF02985.22 RJW73305.1 - 0.087 13.1 0.0 2.1 8.8 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat Macoilin PF09726.9 RJW73307.1 - 5.1e-101 339.3 47.5 2.1e-73 248.0 1.3 3.7 2 1 0 3 3 3 3 Macoilin family CALCOCO1 PF07888.11 RJW73307.1 - 7.2e-05 21.8 7.3 7.2e-05 21.8 7.3 2.2 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1640 PF07798.11 RJW73307.1 - 0.0059 16.7 8.7 0.0059 16.7 8.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) CENP-T_C PF15511.6 RJW73307.1 - 0.028 14.5 1.0 0.061 13.5 0.1 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Golgin_A5 PF09787.9 RJW73307.1 - 0.17 11.3 32.3 0.92 8.9 9.5 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 ATG16 PF08614.11 RJW73307.1 - 1.9 8.7 70.2 0.072 13.3 24.0 4.2 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) Dehydrin PF00257.19 RJW73308.1 - 0.0077 16.8 0.7 0.0097 16.5 0.7 1.2 1 0 0 1 1 1 1 Dehydrin Fis1_TPR_C PF14853.6 RJW73308.1 - 0.062 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Methyltransf_4 PF02390.17 RJW73308.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DAGK_cat PF00781.24 RJW73309.1 - 2.7e-21 75.5 0.0 4e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Lge1 PF11488.8 RJW73310.1 - 0.095 12.9 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 ShK PF01549.24 RJW73312.1 - 2.2e-05 24.9 6.3 2.2e-05 24.9 6.3 4.2 5 0 0 5 5 5 2 ShK domain-like Lig_chan PF00060.26 RJW73314.1 - 1.1e-32 112.9 1.2 1.9e-32 112.2 1.2 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RJW73314.1 - 1.7e-17 63.7 0.0 3.4e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RJW73314.1 - 1.3e-15 57.4 0.0 6.9e-15 55.1 0.0 2.2 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 PGM_PMM_I PF02878.16 RJW73315.1 - 1.6e-20 73.2 0.1 4.6e-09 36.1 0.0 2.9 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 RJW73315.1 - 5e-06 26.6 0.0 2.2e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 RJW73315.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.7 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PsaL PF02605.15 RJW73316.1 - 0.014 15.0 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI DUF3377 PF11857.8 RJW73316.1 - 0.026 14.4 0.3 0.042 13.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 RJW73316.1 - 0.029 14.3 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 RJW73316.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.16 RJW73316.1 - 0.086 11.6 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 RJW73316.1 - 0.099 13.5 0.0 0.12 13.3 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 RJW73316.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Protocadherin SLC35F PF06027.12 RJW73318.1 - 3.5e-42 144.9 19.4 5.2e-42 144.4 19.4 1.2 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 RJW73318.1 - 1.4e-06 27.5 1.1 1.4e-06 27.5 1.1 2.1 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 RJW73318.1 - 5.7e-05 23.3 22.7 0.018 15.2 0.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family ARL6IP6 PF15062.6 RJW73318.1 - 0.91 9.7 3.7 52 4.1 0.0 3.2 1 1 2 3 3 3 0 Haemopoietic lineage transmembrane helix Presenilin PF01080.17 RJW73319.1 - 1.5e-150 501.4 7.9 1.9e-150 501.1 7.9 1.1 1 0 0 1 1 1 1 Presenilin GPS PF01825.21 RJW73320.1 - 9.5e-09 35.7 5.0 3e-08 34.0 5.0 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif SapB_1 PF05184.15 RJW73321.1 - 5.7e-07 29.4 0.7 3.8e-06 26.8 0.1 2.2 2 1 0 2 2 2 1 Saposin-like type B, region 1 SapB_2 PF03489.17 RJW73321.1 - 0.017 15.2 1.8 0.2 11.8 0.1 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 2 Ins_P5_2-kin PF06090.12 RJW73321.1 - 0.018 14.5 0.2 0.02 14.3 0.2 1.0 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase DUF2675 PF11247.8 RJW73321.1 - 0.019 15.1 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) zf-H2C2_2 PF13465.6 RJW73322.1 - 1 9.9 20.9 8.4 7.0 0.8 5.8 5 0 0 5 5 5 0 Zinc-finger double domain Ribosomal_L24e PF01246.20 RJW73323.1 - 7.9e-30 102.9 7.3 7.9e-30 102.9 7.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e Spc7 PF08317.11 RJW73324.1 - 8.6e-05 21.6 20.6 8.6e-05 21.6 20.6 4.8 2 2 2 5 5 5 3 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 RJW73324.1 - 0.0011 19.2 2.4 0.0011 19.2 2.4 6.5 3 2 2 6 6 6 3 TATA element modulatory factor 1 TATA binding Myosin_tail_1 PF01576.19 RJW73324.1 - 0.0069 14.3 65.3 0.057 11.2 31.1 2.7 1 1 1 2 2 2 2 Myosin tail PspA_IM30 PF04012.12 RJW73324.1 - 0.0076 15.8 6.0 0.0076 15.8 6.0 4.2 2 2 2 4 4 4 1 PspA/IM30 family COG2 PF06148.11 RJW73324.1 - 0.0096 16.0 8.0 0.0096 16.0 8.0 5.1 3 2 1 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 CALCOCO1 PF07888.11 RJW73324.1 - 0.029 13.2 59.0 0.27 10.1 27.6 3.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FliJ PF02050.16 RJW73324.1 - 0.057 13.6 52.6 0.55 10.5 11.8 5.7 2 1 4 6 6 6 0 Flagellar FliJ protein NPV_P10 PF05531.12 RJW73324.1 - 0.066 13.7 0.8 0.066 13.7 0.8 6.7 1 1 2 3 3 1 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 RJW73324.1 - 0.26 11.7 53.4 2.2 8.7 13.4 4.1 1 1 3 4 4 4 0 Fez1 Glyco_hydro_17 PF00332.18 RJW73324.1 - 0.29 10.7 1.8 0.57 9.7 1.8 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 HMMR_N PF15905.5 RJW73324.1 - 0.54 9.7 64.0 0.33 10.4 21.5 3.7 2 1 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal HTH_20 PF12840.7 RJW73324.1 - 0.7 10.0 6.6 0.85 9.7 0.1 4.1 3 1 0 3 3 3 0 Helix-turn-helix domain DUF4407 PF14362.6 RJW73324.1 - 0.79 9.0 51.1 16 4.7 14.2 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 RJW73324.1 - 2.5 8.6 79.9 2.1 8.9 6.4 6.6 1 1 5 6 6 6 0 Apg6 coiled-coil region AAA_13 PF13166.6 RJW73324.1 - 2.5 6.6 50.0 0.012 14.3 8.5 3.2 1 1 2 3 3 3 0 AAA domain TPR_MLP1_2 PF07926.12 RJW73324.1 - 5.6 7.0 75.4 1.7 8.7 13.3 6.5 3 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 RJW73324.1 - 5.9 4.3 60.0 1.9 5.9 30.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) GTP-bdg_M PF16360.5 RJW73324.1 - 7.3 7.3 29.3 1.7 9.3 0.2 6.5 4 3 1 5 5 5 0 GTP-binding GTPase Middle Region Clathrin_lg_ch PF01086.17 RJW73326.1 - 3.9e-16 59.8 3.4 6.5e-16 59.1 3.4 1.4 1 1 0 1 1 1 1 Clathrin light chain GalP_UDP_transf PF01087.22 RJW73328.1 - 2.4e-57 194.3 0.0 5e-57 193.3 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 RJW73328.1 - 3.2e-47 160.3 0.0 7.7e-47 159.1 0.0 1.6 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 RJW73328.1 - 0.12 13.1 0.0 0.96 10.2 0.0 2.4 3 1 0 3 3 3 0 HIT domain Roc PF08477.13 RJW73331.1 - 0.068 13.4 0.0 0.076 13.2 0.0 1.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 RJW73332.1 - 3.5e-25 88.9 0.0 5.1e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW73332.1 - 1.6e-13 50.6 0.0 2.2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW73332.1 - 2.5e-08 33.1 0.7 3.9e-08 32.5 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RJW73332.1 - 2.2e-05 24.5 3.9 0.088 12.7 0.1 3.4 3 1 0 4 4 4 2 Phosphotransferase enzyme family Ig_3 PF13927.6 RJW73334.1 - 2.5e-16 60.0 0.4 7.5e-13 48.9 0.0 3.8 3 1 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 RJW73334.1 - 5.4e-13 48.8 0.0 3.7e-12 46.2 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RJW73334.1 - 1.9e-10 41.0 4.0 1.2e-09 38.4 0.0 3.9 4 1 0 4 4 4 1 Immunoglobulin domain ig PF00047.25 RJW73334.1 - 4.1e-06 26.9 0.0 5.7e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain ZU5 PF00791.20 RJW73334.1 - 3.4e-05 24.1 0.0 7.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain V-set PF07686.17 RJW73334.1 - 0.002 18.3 1.2 6.1 7.1 0.1 4.2 4 0 0 4 4 4 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 RJW73334.1 - 0.016 15.2 0.0 0.067 13.3 0.0 2.0 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain RVT_1 PF00078.27 RJW73336.1 - 7.2e-09 35.5 0.2 3.1e-05 23.6 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5641 PF18701.1 RJW73337.1 - 8.9e-31 105.9 2.6 3.1e-30 104.2 2.6 2.1 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Peptidase_A17 PF05380.13 RJW73337.1 - 7.6e-30 104.0 0.0 2.4e-29 102.4 0.0 1.9 1 0 0 1 1 1 1 Pao retrotransposon peptidase Integrase_H2C2 PF17921.1 RJW73337.1 - 1.8e-08 34.4 1.7 5.5e-08 32.8 1.7 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RJW73337.1 - 9.7e-08 32.2 0.0 2.5e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 RJW73337.1 - 0.0002 21.0 0.0 0.00045 19.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TetR_C_27 PF17935.1 RJW73337.1 - 0.076 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain gag-asp_proteas PF13975.6 RJW73337.1 - 0.11 13.0 0.0 0.48 11.0 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Fcf2 PF08698.11 RJW73340.1 - 3.5e-22 78.6 0.6 8e-22 77.5 0.6 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Thioredoxin PF00085.20 RJW73341.1 - 1.4e-22 79.6 0.0 1.8e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 RJW73341.1 - 0.00016 20.7 0.0 0.00019 20.5 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_8 PF13905.6 RJW73341.1 - 0.00036 20.8 0.0 0.002 18.4 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 RJW73341.1 - 0.001 19.2 0.0 0.0027 17.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RJW73341.1 - 0.0017 18.3 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 RJW73341.1 - 0.008 16.0 0.0 0.009 15.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 RJW73341.1 - 0.015 15.7 0.2 0.089 13.3 0.1 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain OST3_OST6 PF04756.13 RJW73341.1 - 0.068 12.5 0.1 0.085 12.2 0.1 1.3 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 RJW73342.1 - 2.2e-36 124.0 1.4 1.8e-25 88.9 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 RJW73342.1 - 1.5e-10 41.3 0.4 6.5e-10 39.2 0.1 1.9 1 1 1 2 2 2 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 RJW73342.1 - 1.2e-08 35.1 3.8 0.11 12.8 0.0 4.1 2 2 1 3 3 3 3 Thioredoxin-like Thioredoxin_2 PF13098.6 RJW73342.1 - 1.3e-08 35.3 1.4 0.00098 19.5 0.1 3.2 2 2 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 RJW73342.1 - 1.5e-07 31.1 2.7 0.00034 20.1 0.3 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family HyaE PF07449.11 RJW73342.1 - 3.3e-06 27.0 0.0 0.0065 16.4 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 RJW73342.1 - 5e-06 26.4 1.7 0.00025 21.0 0.1 2.4 1 1 0 2 2 2 1 AhpC/TSA family DIM1 PF02966.16 RJW73342.1 - 5.6e-05 22.9 1.2 0.15 11.8 0.4 2.2 2 0 0 2 2 2 2 Mitosis protein DIM1 Thioredoxin_9 PF14595.6 RJW73342.1 - 0.0001 22.1 0.2 0.0029 17.4 0.1 2.3 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 RJW73342.1 - 0.00012 22.2 0.3 0.098 12.9 0.1 2.7 2 1 0 2 2 2 2 Thioredoxin-like Phosducin PF02114.16 RJW73342.1 - 0.0003 19.8 0.1 0.00092 18.2 0.0 1.6 1 1 1 2 2 2 1 Phosducin Peptidase_S49_N PF08496.10 RJW73342.1 - 0.02 14.9 2.6 0.033 14.2 0.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DDE_Tnp_1_2 PF13586.6 RJW73342.1 - 0.023 15.1 0.0 0.051 13.9 0.0 1.7 1 1 0 1 1 1 0 Transposase DDE domain DUF1281_C PF18406.1 RJW73342.1 - 0.025 14.3 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 Ferredoxin-like domain in Api92-like protein Kinesin PF00225.23 RJW73344.1 - 1.6e-93 313.3 0.0 3.8e-93 312.0 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RJW73344.1 - 3e-16 59.7 0.6 5.9e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding WD40 PF00400.32 RJW73344.1 - 2.6e-05 24.9 1.0 0.0013 19.5 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4250 PF14056.6 RJW73344.1 - 0.077 13.0 1.0 6.2 6.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Shugoshin_N PF07558.11 RJW73344.1 - 0.14 12.0 3.0 8.7 6.3 0.2 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region NPV_P10 PF05531.12 RJW73344.1 - 0.72 10.4 15.2 18 5.9 0.1 5.1 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 RJW73344.1 - 5.2 7.1 15.3 1.6 8.8 1.1 4.3 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_1 PF00076.22 RJW73345.1 - 3.3e-14 52.4 0.0 8e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_23 PF13476.6 RJW73346.1 - 1.5e-29 104.0 6.3 1.5e-29 104.0 6.3 7.4 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.19 RJW73346.1 - 1.8e-06 27.5 2.7 2e-05 24.1 0.0 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RJW73346.1 - 8.9e-05 22.4 0.1 0.0014 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad50_zn_hook PF04423.14 RJW73346.1 - 0.00011 22.0 0.1 0.00011 22.0 0.1 5.8 5 0 0 5 5 5 1 Rad50 zinc hook motif AAA_29 PF13555.6 RJW73346.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 RJW73346.1 - 0.022 13.4 0.0 0.022 13.4 0.0 6.1 2 1 3 5 5 5 0 AAA domain Roc PF08477.13 RJW73346.1 - 0.061 13.5 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Thioredoxin_2 PF13098.6 RJW73346.1 - 0.11 13.0 0.5 36 4.9 0.0 3.6 3 0 0 3 3 3 0 Thioredoxin-like domain AAA PF00004.29 RJW73346.1 - 0.13 12.6 1.2 1.7 9.1 0.1 3.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cyt-b5 PF00173.28 RJW73348.1 - 8e-24 83.6 0.1 1.6e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Integrase_H2C2 PF17921.1 RJW73348.1 - 6e-10 39.1 0.3 6e-10 39.1 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain MetallophosC PF16370.5 RJW73349.1 - 0.04 14.2 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase Thioredoxin PF00085.20 RJW73351.1 - 3.5e-24 84.8 0.1 4.1e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RJW73351.1 - 6e-07 29.9 0.4 1.1e-05 25.9 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RJW73351.1 - 1e-06 29.0 0.4 0.01 16.1 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 RJW73351.1 - 1e-06 28.5 0.1 1.2e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 RJW73351.1 - 1.3e-06 27.6 0.0 1.5e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.10 RJW73351.1 - 1.7e-05 24.6 0.1 8.5e-05 22.3 0.1 1.7 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 RJW73351.1 - 5.2e-05 23.1 0.4 0.00028 20.8 0.4 1.8 1 1 0 1 1 1 1 AhpC/TSA family HyaE PF07449.11 RJW73351.1 - 7.7e-05 22.6 0.0 9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 RJW73351.1 - 0.00074 19.0 0.1 0.0008 18.8 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 RJW73351.1 - 0.0068 16.6 0.2 0.012 15.8 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like CENP-P PF13096.6 RJW73351.1 - 0.029 14.1 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DDE_Tnp_IS1595 PF12762.7 RJW73352.1 - 0.0015 18.5 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DSHCT PF08148.12 RJW73352.1 - 0.0074 16.0 0.1 0.024 14.3 0.0 1.7 1 1 0 1 1 1 1 DSHCT (NUC185) domain DnaJ PF00226.31 RJW73354.1 - 4.3e-19 68.4 3.2 5.5e-19 68.1 0.9 2.5 3 0 0 3 3 3 1 DnaJ domain SAE2 PF08573.10 RJW73354.1 - 0.0022 19.1 9.2 0.08 14.1 0.1 3.6 2 1 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Filament_head PF04732.14 RJW73354.1 - 6.1 7.8 15.5 12 6.9 1.5 3.6 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region EF-hand_1 PF00036.32 RJW73355.1 - 5.7e-29 97.5 6.9 2e-05 23.8 0.3 6.4 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 RJW73355.1 - 1.7e-25 86.7 6.0 4.2e-05 23.2 0.1 6.3 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.6 RJW73355.1 - 2.4e-21 76.0 6.6 2.4e-06 27.9 0.2 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW73355.1 - 6.8e-21 72.8 14.5 0.00037 19.9 0.3 6.7 7 0 0 7 7 7 6 EF hand SPARC_Ca_bdg PF10591.9 RJW73355.1 - 2.3e-09 37.5 5.2 0.02 15.2 0.2 3.8 2 2 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 RJW73355.1 - 6.3e-09 35.6 6.6 0.12 12.2 0.4 5.5 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_9 PF14658.6 RJW73355.1 - 0.0067 16.7 0.4 2.2 8.6 0.0 3.8 4 1 1 5 5 5 1 EF-hand domain VasL PF12486.8 RJW73355.1 - 0.04 13.8 0.2 0.16 11.8 0.1 2.0 2 1 1 3 3 3 0 Type VI secretion system, EvfB, or VasL Globin PF00042.22 RJW73356.1 - 2.1e-11 44.3 0.0 3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Globin Protoglobin PF11563.8 RJW73356.1 - 0.012 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Protoglobin Y_phosphatase2 PF03162.13 RJW73356.1 - 0.039 13.5 0.2 0.051 13.2 0.2 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family 7tm_1 PF00001.21 RJW73359.1 - 1e-12 47.9 18.8 1.7e-08 34.1 7.6 3.5 4 0 0 4 4 4 3 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.27 RJW73361.1 - 0.022 14.3 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5040 PF16443.5 RJW73361.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) HLH PF00010.26 RJW73362.1 - 6.5e-12 45.2 3.2 1.3e-11 44.2 2.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SHIPPO-rpt PF07004.12 RJW73363.1 - 0.00016 22.4 25.6 2.7 9.1 0.0 8.7 9 0 0 9 9 9 5 Sperm-tail PG-rich repeat Thioredoxin PF00085.20 RJW73364.1 - 1.6e-27 95.4 0.1 1.8e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RJW73364.1 - 5.7e-08 33.0 0.0 1.8e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 RJW73364.1 - 2.1e-07 30.9 0.0 3.2e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 RJW73364.1 - 5.5e-07 30.0 0.0 3e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RJW73364.1 - 9.1e-05 22.6 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 RJW73364.1 - 0.00031 20.5 0.0 0.00033 20.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 RJW73364.1 - 0.00075 19.2 0.1 0.0021 17.8 0.0 1.7 1 1 1 2 2 2 1 Redoxin DIM1 PF02966.16 RJW73364.1 - 0.0065 16.2 0.0 0.0069 16.2 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Phosducin PF02114.16 RJW73364.1 - 0.012 14.5 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Phosducin TraF PF13728.6 RJW73364.1 - 0.031 14.1 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 RJW73364.1 - 0.091 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE FLYWCH PF04500.16 RJW73365.1 - 0.016 15.3 0.1 0.7 10.0 0.1 2.4 2 0 0 2 2 2 0 FLYWCH zinc finger domain Nipped-B_C PF12830.7 RJW73365.1 - 0.088 12.7 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus RVT_1 PF00078.27 RJW73366.1 - 1.2e-44 152.5 0.0 2.3e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GCFC PF07842.12 RJW73366.1 - 1.7e-21 77.1 0.3 5.5e-21 75.4 0.3 1.9 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Exo_endo_phos_2 PF14529.6 RJW73366.1 - 8.8e-07 28.8 0.0 2.5e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW73366.1 - 2.4e-06 27.2 0.3 2.4e-06 27.2 0.3 2.6 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family Draxin PF15550.6 RJW73366.1 - 0.14 12.0 4.7 0.26 11.1 0.4 2.5 2 0 0 2 2 2 0 Draxin Peptidase_A17 PF05380.13 RJW73367.1 - 2.5e-07 30.9 0.0 4.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase RVT_1 PF00078.27 RJW73367.1 - 7.3e-06 25.7 0.0 9.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BAG6 PF12057.8 RJW73367.1 - 0.05 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 BCL2-associated athanogene 6 Methyltransf_23 PF13489.6 RJW73368.1 - 4.8e-16 59.0 0.0 6.4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RJW73368.1 - 6.8e-13 49.2 0.0 1.3e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW73368.1 - 1.1e-12 48.5 0.0 2.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RJW73368.1 - 1.4e-09 38.5 0.0 2.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW73368.1 - 2.3e-06 27.5 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RJW73368.1 - 4.3e-05 23.0 0.0 0.00026 20.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 RJW73368.1 - 0.0017 17.8 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 RJW73368.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Thioredoxin PF00085.20 RJW73369.1 - 3.3e-11 43.1 0.0 5.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 RJW73369.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 RJW73369.1 - 0.074 13.0 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA family GIY-YIG PF01541.24 RJW73371.1 - 0.013 15.7 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain PAE PF03283.13 RJW73372.1 - 3.7e-42 144.7 0.3 8.3e-41 140.3 0.3 2.3 1 1 0 1 1 1 1 Pectinacetylesterase Ndufs5 PF10200.9 RJW73373.1 - 3.1e-05 24.1 0.2 5.5e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa JmjC PF02373.22 RJW73374.1 - 7.6e-22 77.9 0.0 2.4e-21 76.3 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 RJW73374.1 - 9.3e-22 78.0 0.1 2.5e-21 76.5 0.1 1.7 1 0 0 1 1 1 1 Cupin-like domain UPA PF17217.3 RJW73375.1 - 8.2e-31 106.8 0.0 1.9e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 RJW73375.1 - 2.7e-27 95.0 0.0 5.8e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain Ig_3 PF13927.6 RJW73375.1 - 5.2e-12 46.2 0.0 3.6e-11 43.5 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RJW73375.1 - 4.6e-09 36.2 0.0 9.2e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 RJW73375.1 - 1.4e-08 34.8 0.0 5.4e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RJW73375.1 - 1.8e-07 31.4 0.0 1.4e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 RJW73375.1 - 0.0011 19.0 0.0 0.0079 16.2 0.0 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RJW73375.1 - 0.011 15.9 2.0 7 6.9 0.1 3.4 2 1 1 3 3 3 0 Immunoglobulin V-set domain Ig_6 PF18452.1 RJW73375.1 - 0.073 12.7 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Inv-AAD PF18785.1 RJW73375.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Invertebrate-AID/APOBEC-deaminase Sugar_tr PF00083.24 RJW73376.1 - 9.4e-39 133.5 23.6 1.5e-38 132.8 23.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RJW73376.1 - 3.5e-15 55.8 49.3 4.8e-09 35.6 26.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_MOT1 PF16983.5 RJW73376.1 - 0.0076 16.6 1.6 0.0076 16.6 1.6 2.4 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily PDCD9 PF07147.12 RJW73377.1 - 1.9e-09 37.2 0.0 3.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) Bclx_interact PF08945.10 RJW73378.1 - 0.004 16.9 0.1 0.008 15.9 0.1 1.4 1 0 0 1 1 1 1 Bcl-x interacting, BH3 domain AAA_6 PF12774.7 RJW73379.1 - 1.2e-143 478.0 0.0 8.1e-142 472.0 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RJW73379.1 - 1.6e-119 399.6 4.1 1.6e-119 399.6 4.1 2.6 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RJW73379.1 - 1.7e-91 306.6 0.0 4.4e-91 305.3 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RJW73379.1 - 1.3e-89 300.0 0.0 3e-89 298.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RJW73379.1 - 1.9e-85 285.4 4.0 1.4e-83 279.3 1.8 3.6 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 RJW73379.1 - 1.2e-67 226.9 0.9 1.8e-60 203.6 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RJW73379.1 - 4.9e-52 176.1 0.0 1.1e-51 174.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RJW73379.1 - 3.1e-47 161.3 1.9 8.8e-47 159.8 1.9 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RJW73379.1 - 1.7e-37 128.1 1.5 4.4e-37 126.8 0.1 2.7 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RJW73379.1 - 1.4e-21 76.9 1.1 3.9e-07 30.2 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RJW73379.1 - 5.6e-19 68.2 0.0 8.1e-18 64.5 0.0 3.2 2 0 0 2 2 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RJW73379.1 - 1.8e-17 63.7 0.0 7.7e-17 61.6 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 RJW73379.1 - 1.1e-07 32.3 2.1 0.15 12.5 0.0 4.6 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW73379.1 - 5e-07 30.3 0.1 0.98 9.8 0.0 5.3 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 RJW73379.1 - 3.1e-06 27.5 0.5 0.27 11.5 0.0 4.7 4 0 0 4 4 4 2 AAA domain Roc PF08477.13 RJW73379.1 - 0.0013 19.0 0.2 4.1 7.6 0.0 3.3 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RJW73379.1 - 0.0014 18.1 0.1 1 8.7 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein AAA_29 PF13555.6 RJW73379.1 - 0.0045 16.7 1.9 4 7.2 0.0 4.5 5 0 0 5 5 4 1 P-loop containing region of AAA domain AAA_19 PF13245.6 RJW73379.1 - 0.0065 16.8 5.5 1.9 8.8 0.0 4.5 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 RJW73379.1 - 0.022 14.1 0.0 2.8 7.2 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 RJW73379.1 - 0.039 14.5 0.1 18 5.9 0.0 3.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 RJW73379.1 - 0.072 13.5 0.1 2.9 8.3 0.0 3.2 3 0 0 3 3 2 0 RNA helicase Mg_chelatase PF01078.21 RJW73379.1 - 0.084 12.2 0.1 4.5 6.6 0.1 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 RJW73379.1 - 0.094 12.4 2.1 11 5.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 RJW73379.1 - 0.13 12.8 1.5 55 4.3 0.0 4.4 4 0 0 4 4 4 0 ABC transporter SMC_N PF02463.19 RJW73379.1 - 0.19 11.2 0.0 2.6 7.4 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_11 PF13086.6 RJW73379.1 - 2.8 7.6 8.4 14 5.4 0.0 4.7 6 0 0 6 6 4 0 AAA domain Sec8_exocyst PF04048.14 RJW73379.1 - 8.6 6.2 8.6 11 5.9 1.5 3.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Metallophos PF00149.28 RJW73380.1 - 1.7e-10 41.7 0.5 0.00014 22.4 0.0 2.7 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase CASP_C PF08172.12 RJW73382.1 - 2.2e-59 200.8 3.9 2.2e-59 200.8 3.9 6.0 3 2 3 6 6 6 3 CASP C terminal DUF4407 PF14362.6 RJW73382.1 - 9.5e-05 21.9 4.0 9.5e-05 21.9 4.0 4.7 1 1 2 4 4 4 1 Domain of unknown function (DUF4407) DUF2205 PF10224.9 RJW73382.1 - 0.033 14.2 0.2 0.033 14.2 0.2 6.4 4 2 1 5 5 5 0 Short coiled-coil protein Pox_A_type_inc PF04508.12 RJW73382.1 - 0.083 12.8 13.5 1.5 8.8 0.5 5.1 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat GIT_CC PF16559.5 RJW73382.1 - 0.11 12.3 0.2 0.11 12.3 0.2 6.2 6 1 0 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor PKcGMP_CC PF16808.5 RJW73382.1 - 0.27 11.1 10.2 13 5.7 0.1 4.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase IL11 PF07400.11 RJW73382.1 - 0.39 10.3 9.7 0.1 12.2 0.6 3.2 3 0 0 3 3 3 0 Interleukin 11 DUF4618 PF15397.6 RJW73382.1 - 3.5 7.0 42.9 2 7.7 4.7 5.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4618) Globin PF00042.22 RJW73383.1 - 5.3e-10 39.8 0.0 7.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Globin Dynein_light PF01221.18 RJW73384.1 - 1.8e-17 63.4 0.2 3.3e-17 62.6 0.2 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4113 PF13438.6 RJW73384.1 - 0.0025 17.9 0.0 5.6 7.1 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4113) DUF3084 PF11283.8 RJW73384.1 - 0.0088 16.0 0.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3084) UPF0552 PF10574.9 RJW73384.1 - 0.062 12.6 0.1 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Arp2/3-interacting proteins Arpin RNA_pol_Rpb5_C PF01191.19 RJW73384.1 - 0.6 10.0 2.4 27 4.7 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain TRAP_beta PF05753.14 RJW73385.1 - 1.3e-37 129.0 0.0 1.5e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CARDB PF07705.11 RJW73385.1 - 0.012 15.9 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 CARDB BatD PF13584.6 RJW73385.1 - 0.076 11.8 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance CDC73_N PF16050.5 RJW73387.1 - 8.9e-53 179.5 0.1 7.4e-39 133.8 0.0 3.3 2 1 0 3 3 3 3 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 RJW73387.1 - 7.5e-47 158.9 0.4 1.6e-46 157.9 0.4 1.6 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal zf-C4 PF00105.18 RJW73390.1 - 1.5e-14 54.2 8.6 1.5e-14 54.2 8.6 2.3 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW73390.1 - 0.0018 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PSI PF01437.25 RJW73393.1 - 0.00026 21.5 9.1 0.00026 21.5 9.1 2.5 2 0 0 2 2 2 1 Plexin repeat Cys_box PF17869.1 RJW73393.1 - 0.069 13.3 3.6 0.21 11.7 3.3 2.0 1 1 0 1 1 1 0 Anosmin cysteine rich domain TMEM154 PF15102.6 RJW73393.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.5 2 1 1 3 3 3 0 TMEM154 protein family YtfJ_HI0045 PF09695.10 RJW73393.1 - 3.8 7.1 5.8 2.2 7.9 0.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (YtfJ_HI0045) Lebercilin PF15619.6 RJW73394.1 - 5.6e-46 156.7 36.6 5.6e-46 156.7 36.6 2.5 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease zf-AD PF07776.15 RJW73394.1 - 0.16 12.2 1.5 2 8.7 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Putative_PNPOx PF01243.20 RJW73395.1 - 7.6e-26 90.1 0.0 9.7e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 RJW73395.1 - 5.7e-07 30.1 0.0 1.2e-06 29.0 0.0 1.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 RJW73395.1 - 0.052 13.1 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like CNOT1_HEAT_N PF16419.5 RJW73396.1 - 7e-06 25.9 0.5 0.12 12.1 0.1 2.5 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF2280 PF10045.9 RJW73396.1 - 0.0014 18.9 7.1 0.42 10.9 1.1 2.9 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2280) T3SSipB PF16535.5 RJW73396.1 - 0.0019 18.7 21.0 0.038 14.5 2.8 2.8 3 1 0 3 3 3 2 Type III cell invasion protein SipB DUF150 PF02576.17 RJW73396.1 - 0.0021 18.4 0.4 4.3 7.8 0.0 2.8 2 0 0 2 2 2 2 RimP N-terminal domain DUF1759 PF03564.15 RJW73396.1 - 0.015 15.2 19.1 0.49 10.3 1.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) Baculo_PEP_C PF04513.12 RJW73396.1 - 0.049 13.7 9.0 1.1 9.3 0.6 3.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 RJW73396.1 - 0.066 11.8 26.3 0.18 10.4 5.6 3.1 3 0 0 3 3 3 0 Flagellar Assembly Protein A UPF0242 PF06785.11 RJW73396.1 - 0.098 12.8 40.0 1.8 8.6 8.4 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF4241 PF14025.6 RJW73396.1 - 0.18 12.0 6.7 3.9 7.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) DUF3452 PF11934.8 RJW73396.1 - 0.26 10.9 15.1 1.9 8.0 1.5 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3452) Utp12 PF04003.12 RJW73396.1 - 0.34 11.2 10.0 6.1 7.2 0.2 3.9 3 0 0 3 3 3 0 Dip2/Utp12 Family Fib_alpha PF08702.10 RJW73396.1 - 0.49 10.6 35.3 1.4 9.1 5.3 4.7 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF3323 PF11796.8 RJW73396.1 - 0.51 10.2 12.6 3 7.7 3.1 2.6 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) DUF1843 PF08898.10 RJW73396.1 - 1.2 9.6 5.6 22 5.6 0.1 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF1843) Tsc35 PF15079.6 RJW73396.1 - 2 8.0 28.7 0.37 10.3 5.6 2.7 3 0 0 3 3 3 0 Testis-specific protein 35 EF-hand_7 PF13499.6 RJW73396.1 - 3.6 8.1 5.5 41 4.7 0.5 2.8 2 0 0 2 2 2 0 EF-hand domain pair T3SS_basalb_I PF17001.5 RJW73396.1 - 4.5 7.9 15.5 8.9 7.0 3.8 3.8 3 1 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Transketolase_N PF00456.21 RJW73396.1 - 4.8 6.0 10.5 8.5 5.2 1.8 2.4 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain DUF2031 PF09592.10 RJW73396.1 - 4.9 6.6 27.8 0.5 9.8 8.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2031) GHMP_kinases_C PF08544.13 RJW73396.1 - 6 7.3 8.4 23 5.4 0.3 3.3 3 0 0 3 3 3 0 GHMP kinases C terminal TMPIT PF07851.13 RJW73396.1 - 6.2 6.0 30.2 0.6 9.3 1.0 3.5 3 1 0 3 3 3 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 RJW73396.1 - 6.6 6.8 51.0 0.44 10.6 14.6 4.4 3 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Mer2 PF09074.10 RJW73396.1 - 7.9 6.2 18.7 1.4 8.7 3.7 3.4 3 0 0 3 3 3 0 Mer2 PMC2NT PF08066.12 RJW73396.1 - 8.3 7.2 8.3 4.9 7.9 0.5 3.4 3 1 0 3 3 2 0 PMC2NT (NUC016) domain DUF1043 PF06295.12 RJW73396.1 - 9.4 6.3 27.5 5.3 7.1 6.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) RhodobacterPufX PF11511.8 RJW73397.1 - 0.064 12.9 0.4 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 Intrinsic membrane protein PufX GSH_synth_ATP PF03917.17 RJW73398.1 - 4.4e-75 252.8 0.0 6.4e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 RJW73398.1 - 9.9e-27 93.4 0.0 1.8e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF5519 PF17648.1 RJW73398.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5519) KH_1 PF00013.29 RJW73400.1 - 6.1e-15 54.8 0.5 1.1e-14 54.0 0.5 1.4 1 0 0 1 1 1 1 KH domain DUF1897 PF09005.10 RJW73400.1 - 6.9e-13 47.8 8.6 6.9e-13 47.8 8.6 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1897) KH_2 PF07650.17 RJW73400.1 - 0.00067 19.4 0.1 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 KH domain Glyoxalase_4 PF13669.6 RJW73403.1 - 9.4e-23 80.6 0.0 1.3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 RJW73403.1 - 3.9e-13 49.7 0.0 5.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 RJW73403.1 - 4.1e-08 33.5 0.1 5e-08 33.3 0.1 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 RJW73403.1 - 0.0098 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 RJW73403.1 - 0.017 15.9 0.0 0.032 15.0 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain DAP_epimerase PF01678.19 RJW73403.1 - 0.022 14.9 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Diaminopimelate epimerase Strep_pep PF14404.6 RJW73404.1 - 0.0073 16.6 0.0 5 7.5 0.0 2.4 2 0 0 2 2 2 2 Ribosomally synthesized peptide in Streptomyces species Carboxyl_trans PF01039.22 RJW73406.1 - 2.1e-114 382.9 0.0 2.3e-114 382.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ssDBP_DBD PF18361.1 RJW73406.1 - 0.063 13.4 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain MdcE PF06833.11 RJW73406.1 - 0.085 12.3 1.1 0.3 10.5 0.0 2.2 3 0 0 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) Sina PF03145.16 RJW73407.1 - 0.23 11.4 1.7 0.4 10.6 1.7 1.3 1 0 0 1 1 1 0 Seven in absentia protein family DUF1096 PF06493.11 RJW73407.1 - 4.7 7.7 7.7 29 5.2 7.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1096) KH_1 PF00013.29 RJW73409.1 - 5.5e-49 163.9 10.8 1.2e-16 60.3 0.2 3.3 3 0 0 3 3 3 3 KH domain DUF1897 PF09005.10 RJW73409.1 - 1.7e-15 56.2 5.3 1.7e-15 56.2 5.3 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1897) KH_2 PF07650.17 RJW73409.1 - 3e-12 46.2 2.5 0.001 18.9 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 RJW73409.1 - 3.7e-09 36.3 2.3 0.0007 19.4 0.1 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 RJW73409.1 - 0.062 13.4 1.5 6.2 7.0 0.0 3.3 3 0 0 3 3 3 0 NusA-like KH domain Ldh_2 PF02615.14 RJW73410.1 - 0.18 11.0 0.1 0.28 10.3 0.1 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase YlbE PF14003.6 RJW73410.1 - 6.4 7.3 6.9 2.2 8.8 0.2 3.2 3 1 0 3 3 3 0 YlbE-like protein TIP39 PF14980.6 RJW73411.1 - 0.1 12.5 0.1 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 TIP39 peptide Pyr_redox PF00070.27 RJW73411.1 - 0.23 12.0 0.0 0.59 10.7 0.0 1.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cadherin_C_2 PF16492.5 RJW73412.1 - 0.033 14.9 0.4 0.066 14.0 0.4 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal CBM_5_12 PF02839.14 RJW73412.1 - 0.059 14.0 0.1 0.15 12.7 0.1 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain PNP_phzG_C PF10590.9 RJW73413.1 - 3e-19 68.8 1.1 4e-19 68.4 1.1 1.2 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Elong_Iki1 PF10483.9 RJW73414.1 - 6e-07 29.3 1.0 1.7e-06 27.7 0.3 1.8 1 1 0 2 2 2 1 Elongator subunit Iki1 HAP1_N PF04849.13 RJW73415.1 - 1.2e-60 205.3 13.0 4.1e-60 203.6 12.7 1.8 2 0 0 2 2 2 1 HAP1 N-terminal conserved region HMMR_N PF15905.5 RJW73415.1 - 0.09 12.2 6.4 2 7.8 1.0 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SPATA24 PF15175.6 RJW73415.1 - 5 7.0 8.4 8 6.3 1.5 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 TSC22 PF01166.18 RJW73415.1 - 5.1 7.5 5.6 4.3 7.7 0.8 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 RJW73415.1 - 5.9 7.1 10.1 0.26 11.4 1.1 3.0 3 0 0 3 3 3 0 bZIP transcription factor UPF0242 PF06785.11 RJW73415.1 - 7.6 6.6 9.2 16 5.5 1.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TTL PF03133.15 RJW73416.1 - 2.7e-63 213.8 0.0 6.2e-63 212.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RJW73416.1 - 3.9e-06 26.3 0.0 8e-05 22.0 0.0 2.5 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RJW73416.1 - 0.00019 20.8 0.0 0.0098 15.2 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 RJW73416.1 - 0.051 13.6 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain GIY-YIG PF01541.24 RJW73417.1 - 0.13 12.6 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain PPR_long PF17177.4 RJW73418.1 - 1.2e-05 24.8 0.0 2.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 RJW73418.1 - 7.7e-05 22.3 0.1 0.0096 15.6 0.0 3.7 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 RJW73418.1 - 0.001 19.1 0.0 1.3 9.2 0.0 2.6 1 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 RJW73418.1 - 0.002 18.2 0.0 0.45 10.7 0.0 3.9 4 1 0 5 5 5 1 PPR repeat family DUF2981 PF11200.8 RJW73421.1 - 1.1 9.0 3.1 0.72 9.5 1.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2981) EthD PF07110.11 RJW73421.1 - 2.3 9.4 6.8 7.8 7.7 6.8 1.8 1 0 0 1 1 1 0 EthD domain ASH PF15780.5 RJW73422.1 - 1.1e-14 54.4 1.9 0.031 14.5 0.1 7.0 6 2 1 7 7 7 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 RJW73422.1 - 9e-08 32.1 0.0 0.54 10.3 0.0 6.2 7 0 0 7 7 7 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 RJW73422.1 - 9e-05 22.7 2.6 1 9.7 0.0 5.6 5 1 0 5 5 5 1 Transmembrane protein 131-like Pkinase_Tyr PF07714.17 RJW73423.1 - 7e-76 254.9 0.0 4.8e-74 248.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RJW73423.1 - 7.3e-38 130.4 0.0 5e-37 127.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GF_recep_IV PF14843.6 RJW73423.1 - 4.3e-15 55.7 73.2 1e-05 25.4 3.8 6.6 3 2 3 7 7 7 5 Growth factor receptor domain IV Recep_L_domain PF01030.24 RJW73423.1 - 6.4e-14 52.0 0.0 1.4e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Receptor L domain Furin-like PF00757.20 RJW73423.1 - 3.2e-10 40.1 80.9 2.2e-05 24.4 10.2 6.3 3 1 3 6 6 6 5 Furin-like cysteine rich region APH PF01636.23 RJW73423.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 RJW73423.1 - 0.07 12.4 0.1 0.15 11.3 0.1 1.4 1 1 0 1 1 1 0 Kinase-like Frag1 PF10277.9 RJW73427.1 - 1.4e-07 31.3 0.1 1.4e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family RseC_MucC PF04246.12 RJW73428.1 - 0.14 12.2 2.8 0.35 10.8 2.8 1.6 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Stathmin PF00836.19 RJW73430.1 - 0.00011 22.2 3.6 0.00011 22.2 3.6 1.8 1 1 1 2 2 2 1 Stathmin family eIF-3c_N PF05470.12 RJW73430.1 - 0.025 12.9 4.6 0.027 12.8 4.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CENP-I PF07778.11 RJW73430.1 - 2.5 6.7 5.2 2.8 6.5 5.2 1.0 1 0 0 1 1 1 0 Mis6 7tm_1 PF00001.21 RJW73433.1 - 5.7e-63 212.7 14.3 1e-62 211.9 14.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RJW73433.1 - 1.1e-09 38.5 11.5 1.1e-09 38.5 11.5 1.8 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RJW73433.1 - 9.8e-05 22.1 14.1 0.00022 20.9 14.1 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RJW73433.1 - 0.032 13.6 18.4 1.4 8.3 13.7 2.5 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx SIP1 PF04938.12 RJW73434.1 - 1.1e-13 51.4 0.0 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) PHD PF00628.29 RJW73435.1 - 2e-15 56.4 24.1 9e-10 38.3 7.1 2.5 1 1 1 2 2 2 2 PHD-finger SAM_1 PF00536.30 RJW73435.1 - 6.1e-13 49.0 0.1 2.4e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RJW73435.1 - 7.8e-06 25.9 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 RJW73435.1 - 0.00052 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain C1_1 PF00130.22 RJW73435.1 - 0.0092 15.9 2.8 0.0092 15.9 2.8 3.1 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 RJW73435.1 - 0.016 14.8 10.0 0.53 9.9 2.2 2.8 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 RJW73435.1 - 0.17 12.2 17.4 1.1 9.6 1.9 2.8 2 0 0 2 2 2 0 C1 domain Ribosomal_S3_C PF00189.20 RJW73436.1 - 6.9e-22 77.8 0.1 3.4e-21 75.5 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 RJW73436.1 - 1.9e-06 27.6 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 KH domain Mtc PF03820.17 RJW73437.1 - 3.3e-135 450.1 0.0 3.8e-135 449.9 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier NUDIX_2 PF13869.6 RJW73438.1 - 0.056 13.0 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase Peptidase_C97 PF05903.14 RJW73440.1 - 3.2e-33 114.7 0.0 3.2e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 PPPDE putative peptidase domain Topoisom_bac PF01131.20 RJW73441.1 - 7.6e-101 338.1 0.0 1e-100 337.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 RJW73441.1 - 3.1e-29 100.8 8.6 1.5e-14 53.8 0.8 2.8 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.22 RJW73441.1 - 1.1e-18 67.3 0.0 2e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 RJW73441.1 - 1.7e-05 24.5 9.0 0.003 17.3 0.0 4.4 4 0 0 4 4 4 2 Topoisomerase DNA binding C4 zinc finger zf-C2H2_10 PF16588.5 RJW73441.1 - 0.02 14.6 3.0 0.054 13.2 3.0 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 RJW73441.1 - 0.29 11.3 2.5 1.1 9.5 2.5 2.1 1 0 0 1 1 1 0 Zinc knuckle DZR PF12773.7 RJW73441.1 - 0.79 9.8 7.0 5.2 7.2 0.1 3.6 3 0 0 3 3 3 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 RJW73441.1 - 3.8 7.7 4.7 11 6.1 1.0 3.3 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger CUB PF00431.20 RJW73442.1 - 2.9e-18 66.2 0.0 3.4e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 CUB domain fn3 PF00041.21 RJW73443.1 - 4.3e-12 46.2 20.3 0.07 13.5 0.0 9.1 10 0 0 10 10 10 5 Fibronectin type III domain fn3 PF00041.21 RJW73444.1 - 7.1e-26 90.4 5.9 3.1e-08 33.8 0.8 6.6 6 0 0 6 6 6 5 Fibronectin type III domain Vps35 PF03635.17 RJW73446.1 - 2.1e-226 753.9 0.0 2.8e-226 753.5 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RPW8 PF05659.11 RJW73446.1 - 0.068 12.9 0.2 0.58 9.9 0.1 2.5 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 WD40 PF00400.32 RJW73447.1 - 9.4e-55 181.4 22.5 1.4e-09 38.4 0.4 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73447.1 - 8.4e-16 58.0 0.0 0.00052 20.3 0.0 5.6 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW73447.1 - 8e-07 29.1 0.0 0.12 12.2 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RJW73447.1 - 1.4e-05 24.2 0.7 0.015 14.3 0.5 4.2 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 RJW73447.1 - 0.018 13.4 0.0 0.19 10.0 0.0 2.3 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 RJW73447.1 - 0.15 11.8 1.3 3.7 7.3 0.0 3.3 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 RJW73447.1 - 0.16 11.9 0.1 6.3 6.9 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ACBP PF00887.19 RJW73448.1 - 7.1e-25 87.0 0.0 1.5e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.7 RJW73448.1 - 2.3e-24 85.8 0.1 3.6e-16 59.5 0.1 2.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW73448.1 - 6.4e-21 74.2 2.5 1.2e-12 47.8 0.5 3.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW73448.1 - 1.6e-17 63.6 0.1 4.3e-12 46.3 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RJW73448.1 - 5.3e-17 61.4 2.3 8.3e-08 32.4 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 RJW73448.1 - 1.3e-13 49.8 0.0 1.7e-05 24.8 0.1 4.0 5 0 0 5 5 5 2 Ankyrin repeat DSL PF01414.19 RJW73449.1 - 5.8e-12 45.7 0.4 5.8e-12 45.7 0.4 5.4 3 1 1 5 5 5 1 Delta serrate ligand EGF PF00008.27 RJW73449.1 - 1.9e-08 34.4 17.6 6.2e-06 26.4 7.4 5.6 5 0 0 5 5 5 2 EGF-like domain EGF_2 PF07974.13 RJW73449.1 - 0.00024 21.4 6.2 0.00024 21.4 6.2 5.8 5 0 0 5 5 5 2 EGF-like domain hEGF PF12661.7 RJW73449.1 - 0.0097 16.5 2.4 0.0097 16.5 2.4 6.1 5 0 0 5 5 5 2 Human growth factor-like EGF MM_CoA_mutase PF01642.22 RJW73450.1 - 1.9e-237 788.9 1.5 2.3e-237 788.6 1.5 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 RJW73450.1 - 5.1e-16 58.8 0.2 1.2e-15 57.6 0.2 1.7 1 0 0 1 1 1 1 B12 binding domain HisG_C PF08029.11 RJW73450.1 - 0.3 11.3 2.1 1.1 9.5 0.1 2.7 3 0 0 3 3 3 0 HisG, C-terminal domain LRR_6 PF13516.6 RJW73451.1 - 3e-19 67.4 17.6 0.031 14.3 0.3 8.8 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 RJW73451.1 - 1e-07 32.1 19.7 5.7e-05 23.4 2.0 5.6 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW73451.1 - 0.002 18.4 17.9 0.78 10.5 0.0 7.3 8 0 0 8 8 8 2 Leucine Rich Repeat EF-hand_8 PF13833.6 RJW73451.1 - 0.12 12.2 0.0 0.39 10.6 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair LRR_8 PF13855.6 RJW73451.1 - 0.14 12.0 24.6 0.29 10.9 3.4 6.0 4 2 2 6 6 6 0 Leucine rich repeat HNOBA PF07701.14 RJW73452.1 - 1.1e-45 155.8 6.5 1.6e-22 80.1 1.5 2.6 2 1 0 2 2 2 2 Heme NO binding associated HNOB PF07700.15 RJW73452.1 - 1.4e-39 135.7 0.1 4.6e-39 134.0 0.0 1.9 2 0 0 2 2 2 1 Haem-NO-binding Guanylate_cyc PF00211.20 RJW73452.1 - 4.6e-29 101.3 1.8 5.2e-20 71.8 0.1 2.4 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain P63C PF10546.9 RJW73452.1 - 0.044 14.4 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 P63C domain Ig_3 PF13927.6 RJW73453.1 - 2.8e-19 69.5 0.1 0.00011 22.7 0.0 5.3 3 2 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RJW73453.1 - 1.1e-15 57.4 0.0 0.00043 20.3 0.0 5.0 4 1 0 4 4 4 3 Immunoglobulin I-set domain ig PF00047.25 RJW73453.1 - 3.6e-14 52.7 0.0 0.011 15.9 0.0 5.3 4 1 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 RJW73453.1 - 9e-11 42.0 0.0 0.079 13.3 0.0 5.2 5 0 0 5 5 5 2 Immunoglobulin domain Ig_6 PF18452.1 RJW73453.1 - 5.7e-09 35.4 0.1 0.056 13.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RJW73453.1 - 7.8e-06 26.0 0.2 0.31 11.2 0.1 4.3 4 1 0 5 5 5 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 RJW73453.1 - 9.7e-05 22.4 0.1 0.51 10.4 0.0 3.4 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Rib_hydrolayse PF02267.17 RJW73454.1 - 8.9e-64 215.2 0.6 1.1e-63 214.9 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase Thioredoxin_15 PF18403.1 RJW73454.1 - 0.014 15.3 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DEAD PF00270.29 RJW73455.1 - 9e-35 120.0 0.0 1.4e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Exo_endo_phos PF03372.23 RJW73455.1 - 2.3e-05 24.0 0.3 5.8e-05 22.7 0.3 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_22 PF13401.6 RJW73455.1 - 0.001 19.4 0.6 0.0064 16.8 0.1 2.6 3 0 0 3 3 3 1 AAA domain Chon_Sulph_att PF06566.11 RJW73455.1 - 0.0067 16.3 0.2 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 Chondroitin sulphate attachment domain Pro-MCH PF05824.12 RJW73455.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) UTP25 PF06862.12 RJW73455.1 - 0.13 11.0 0.0 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Cnl2_NKP2 PF09447.10 RJW73456.1 - 0.056 13.6 0.1 0.16 12.2 0.1 1.7 2 0 0 2 2 2 0 Cnl2/NKP2 family protein nlz1 PF12402.8 RJW73457.1 - 0.18 12.3 0.2 0.46 11.0 0.2 1.6 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 Ank_2 PF12796.7 RJW73458.1 - 2.3e-27 95.4 0.4 6.7e-09 36.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW73458.1 - 1.1e-21 76.6 3.2 5.4e-06 26.6 0.0 6.4 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW73458.1 - 6.7e-21 74.4 3.8 1.2e-06 28.9 0.2 6.6 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW73458.1 - 1.1e-18 65.4 2.9 0.0023 18.3 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 RJW73458.1 - 2.7e-16 59.2 10.4 0.026 15.0 0.0 7.6 7 0 0 7 7 7 4 Ankyrin repeat MAP65_ASE1 PF03999.12 RJW73458.1 - 3.2 6.4 6.2 4.5 5.9 6.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ADK PF00406.22 RJW73459.1 - 3.1e-51 173.5 0.0 3.8e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RJW73459.1 - 7.7e-32 110.6 0.0 1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RJW73459.1 - 2.4e-09 37.8 0.0 4.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RJW73459.1 - 1.5e-07 31.7 0.1 3.2e-06 27.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 RJW73459.1 - 2.2e-06 27.5 0.0 0.056 13.1 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Cytidylate_kin PF02224.18 RJW73459.1 - 0.014 15.1 0.6 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 RJW73459.1 - 0.028 14.8 0.0 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RJW73459.1 - 0.039 13.9 0.1 0.21 11.5 0.0 2.0 2 1 0 2 2 2 0 NTPase AAA_22 PF13401.6 RJW73459.1 - 0.054 13.8 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rsd_AlgQ PF04353.13 RJW73459.1 - 0.059 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ SbsC_C PF18058.1 RJW73459.1 - 0.1 12.8 0.5 0.16 12.2 0.5 1.3 1 0 0 1 1 1 0 SbsC C-terminal domain AAA PF00004.29 RJW73459.1 - 0.14 12.6 0.4 0.72 10.3 0.4 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RJW73459.1 - 0.16 12.2 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain LSM PF01423.22 RJW73460.1 - 6.3e-19 67.4 0.1 9.5e-19 66.9 0.1 1.3 1 0 0 1 1 1 1 LSM domain Glutaredoxin PF00462.24 RJW73460.1 - 0.06 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin WD40 PF00400.32 RJW73461.1 - 3.8e-18 65.5 12.4 2.5e-05 24.9 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73461.1 - 3.4e-13 49.7 5.2 0.0014 18.9 0.1 5.0 2 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW73461.1 - 0.026 13.2 3.9 0.37 9.4 0.1 3.2 2 2 2 4 4 4 0 Nucleoporin Nup120/160 LRR_4 PF12799.7 RJW73463.1 - 7.8e-12 45.2 9.5 0.00022 21.5 1.7 4.8 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RJW73463.1 - 8.7e-08 31.9 0.0 0.016 14.7 0.0 3.6 3 1 0 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 RJW73463.1 - 0.00033 20.4 0.2 0.00033 20.4 0.2 4.2 4 2 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 RJW73463.1 - 0.03 14.4 4.5 15 6.0 0.1 4.2 3 0 0 3 3 3 0 Leucine Rich repeat ubiquitin PF00240.23 RJW73463.1 - 0.033 14.0 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin family LRR_1 PF00560.33 RJW73463.1 - 0.27 11.9 9.7 1.7 9.5 0.3 4.7 2 2 1 3 3 3 0 Leucine Rich Repeat DUF1758 PF05585.12 RJW73464.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Laminin_G_2 PF02210.24 RJW73465.1 - 2.7e-37 128.2 0.1 2.8e-08 34.4 0.0 4.5 4 0 0 4 4 4 4 Laminin G domain EGF PF00008.27 RJW73465.1 - 1.1e-36 124.7 287.6 4.9e-05 23.5 9.3 17.7 17 0 0 17 17 17 16 EGF-like domain Laminin_G_1 PF00054.23 RJW73465.1 - 1e-23 84.0 0.0 4.4e-05 23.7 0.0 5.1 4 1 0 4 4 4 4 Laminin G domain WD40 PF00400.32 RJW73465.1 - 1e-15 57.8 6.0 9.1e-09 35.8 0.2 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 RJW73465.1 - 0.0021 17.4 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain EGF_2 PF07974.13 RJW73465.1 - 0.0035 17.7 311.0 0.035 14.5 11.3 17.6 16 1 1 17 17 17 11 EGF-like domain Nup160 PF11715.8 RJW73465.1 - 0.027 13.1 0.0 0.12 11.0 0.0 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 LSM PF01423.22 RJW73466.1 - 9.6e-17 60.4 0.0 1.2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 RJW73466.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DUF2870 PF11069.8 RJW73467.1 - 3.7e-44 149.0 0.2 3.7e-44 149.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 RJW73467.1 - 0.01 15.5 0.1 0.048 13.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family Ras PF00071.22 RJW73468.1 - 0.0011 18.5 0.0 0.026 14.1 0.0 2.1 1 1 0 1 1 1 1 Ras family Arf PF00025.21 RJW73468.1 - 0.066 12.7 0.0 1.6 8.2 0.0 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family Papilin_u7 PF16626.5 RJW73468.1 - 0.13 12.9 0.1 0.44 11.2 0.1 1.9 2 0 0 2 2 2 0 Linking region between Kunitz_BPTI and I-set on papilin Sulfotransfer_4 PF17784.1 RJW73470.1 - 3.5e-68 229.7 0.2 4e-68 229.4 0.2 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW73470.1 - 0.00027 21.4 1.8 0.0015 19.0 0.4 2.6 1 1 1 2 2 2 1 Sulfotransferase family CODH_A_N PF18537.1 RJW73470.1 - 0.0097 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit alpha N-terminal domain PKD_channel PF08016.12 RJW73471.1 - 2.7e-113 378.9 12.6 2.7e-113 378.9 12.6 1.6 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 RJW73471.1 - 1.4e-25 90.0 30.7 6.2e-24 84.6 30.6 2.2 2 0 0 2 2 2 1 Ion transport protein Orai-1 PF07856.12 RJW73471.1 - 0.0027 17.4 7.5 0.0027 17.4 7.5 2.1 3 0 0 3 3 3 1 Mediator of CRAC channel activity EF-hand_8 PF13833.6 RJW73471.1 - 0.07 13.0 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair UME PF08064.13 RJW73471.1 - 0.27 11.2 2.1 22 5.1 0.0 3.1 4 0 0 4 4 4 0 UME (NUC010) domain PWI PF01480.17 RJW73472.1 - 2.6e-12 46.9 0.1 7.9e-12 45.3 0.1 1.9 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 RJW73472.1 - 6.8e-09 35.4 0.0 2.7e-08 33.5 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glutaminase PF04960.15 RJW73473.1 - 8.2e-115 382.9 0.0 1e-114 382.6 0.0 1.1 1 0 0 1 1 1 1 Glutaminase EF-hand_14 PF17959.1 RJW73473.1 - 7.4e-16 58.3 0.2 1.4e-15 57.4 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain Ank_4 PF13637.6 RJW73473.1 - 1.8e-11 44.3 0.1 7.2e-06 26.5 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW73473.1 - 1.2e-09 38.6 0.0 3.8e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW73473.1 - 8.4e-09 35.0 0.1 0.0002 21.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RJW73473.1 - 7.7e-07 29.3 0.0 3.8e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RJW73473.1 - 0.0026 18.1 0.0 1.1 9.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 RJW73475.1 - 3.6e-43 146.1 2.7 8e-12 45.6 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW73475.1 - 4.5e-30 103.3 7.6 4.6e-09 36.4 0.6 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RJW73475.1 - 7.1e-29 99.8 4.5 1.4e-08 35.1 0.1 5.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 RJW73475.1 - 2.2e-22 78.4 6.3 0.001 19.4 0.0 5.5 5 1 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 RJW73475.1 - 4.7e-22 75.7 2.1 0.0056 17.1 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat SOCS_box PF07525.16 RJW73475.1 - 3.2e-09 37.0 1.8 3.4e-09 36.9 0.4 1.8 2 0 0 2 2 2 1 SOCS box HLH PF00010.26 RJW73479.1 - 1.5e-15 56.9 0.4 2.6e-15 56.1 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF773 PF05600.12 RJW73479.1 - 0.22 10.2 0.1 0.33 9.6 0.1 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 tRNA-synt_1g PF09334.11 RJW73482.1 - 8.6e-85 284.8 0.0 2.3e-74 250.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RJW73482.1 - 1e-08 33.9 0.0 0.00019 19.9 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 RJW73482.1 - 0.0049 16.2 0.0 0.087 12.2 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DUF1472 PF07339.12 RJW73482.1 - 0.06 13.9 0.2 0.14 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1472) tRNA-synt_1b PF00579.25 RJW73482.1 - 0.1 11.9 0.0 0.77 9.0 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) zf-met PF12874.7 RJW73485.1 - 3.6e-12 46.2 19.5 1.9e-06 28.0 1.0 4.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RJW73485.1 - 3.8e-10 39.8 10.6 0.00013 22.1 0.6 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 RJW73485.1 - 0.00038 20.2 0.5 0.00038 20.2 0.5 3.3 3 1 0 3 3 3 1 U1 zinc finger zf-C2H2_2 PF12756.7 RJW73485.1 - 0.021 15.1 10.3 0.12 12.7 0.2 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 RJW73485.1 - 0.046 13.9 0.2 0.046 13.9 0.2 2.1 2 0 0 2 2 2 0 DBF zinc finger AKAP95 PF04988.12 RJW73485.1 - 0.24 11.6 5.7 2.8 8.1 0.1 2.2 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-SCNM1 PF15803.5 RJW73485.1 - 0.54 9.9 5.8 2.5 7.8 1.5 3.0 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 zf-C2H2 PF00096.26 RJW73485.1 - 3.8 8.1 11.5 12 6.6 2.2 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 RJW73485.1 - 7.5 6.3 9.7 12 5.6 2.8 2.7 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 RJW73485.1 - 9.8 7.3 18.0 0.72 10.9 0.3 5.0 4 1 0 5 5 5 0 C2H2-type zinc finger Actin PF00022.19 RJW73486.1 - 3.4e-90 302.6 0.0 6.3e-88 295.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RJW73486.1 - 5.9e-06 25.3 0.0 0.0067 15.3 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 RJW73486.1 - 0.0067 16.8 0.0 0.016 15.7 0.0 1.8 1 1 0 1 1 1 1 Cell division protein FtsA ETX_MTX2 PF03318.13 RJW73489.1 - 0.00068 19.5 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF2013 PF09431.10 RJW73490.1 - 9.4e-14 51.8 0.0 4.3e-10 39.9 0.0 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF2013) Ins134_P3_kin PF05770.11 RJW73491.1 - 6.9e-34 117.1 0.0 8e-33 113.6 0.0 1.9 1 1 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain MULE PF10551.9 RJW73492.1 - 2.5e-14 53.4 0.2 3.6e-14 53.0 0.2 1.2 1 0 0 1 1 1 1 MULE transposase domain EF-hand_7 PF13499.6 RJW73493.1 - 6.8e-17 61.7 10.2 3e-09 37.2 5.9 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW73493.1 - 1.2e-11 43.2 16.9 3.6e-05 23.0 0.4 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RJW73493.1 - 1.6e-10 40.7 5.7 2e-07 30.7 3.6 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RJW73493.1 - 3.2e-10 39.1 15.4 1.4e-05 24.6 0.2 5.1 5 1 1 6 6 6 3 EF-hand domain EF-hand_5 PF13202.6 RJW73493.1 - 0.00042 19.7 8.6 0.0017 17.8 0.2 3.1 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 RJW73493.1 - 0.00061 20.1 1.0 0.0026 18.1 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain DUF1948 PF09185.10 RJW73493.1 - 0.053 13.4 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) EF-hand_4 PF12763.7 RJW73493.1 - 1 9.3 3.7 1.5 8.8 0.1 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand RVT_1 PF00078.27 RJW73494.1 - 1.4e-88 296.1 0.1 2.1e-45 155.0 0.0 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) CREPT PF16566.5 RJW73494.1 - 2.7e-34 118.4 6.2 4.8e-20 72.2 2.5 2.9 2 0 0 2 2 2 2 Cell-cycle alteration and expression-elevated protein in tumour Exo_endo_phos_2 PF14529.6 RJW73494.1 - 2.5e-20 72.5 0.3 1.4e-10 41.0 0.0 3.9 3 0 0 3 3 3 2 Endonuclease-reverse transcriptase CTD_bind PF04818.13 RJW73494.1 - 1.3e-10 42.0 0.0 5.1e-10 40.0 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PHD PF00628.29 RJW73494.1 - 0.0021 17.9 6.7 0.0047 16.8 6.7 1.5 1 0 0 1 1 1 1 PHD-finger GCP_N_terminal PF17681.1 RJW73494.1 - 0.037 13.6 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal FliT PF05400.13 RJW73494.1 - 8 7.4 6.1 47 4.9 1.2 3.7 3 0 0 3 3 3 0 Flagellar protein FliT Ins134_P3_kin PF05770.11 RJW73495.1 - 3e-43 147.7 0.0 4.1e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Hormone_3 PF00159.18 RJW73497.1 - 0.0018 18.3 0.6 0.0029 17.7 0.6 1.3 1 0 0 1 1 1 1 Pancreatic hormone peptide GTA_TIM PF13547.6 RJW73497.1 - 0.035 13.4 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 GTA TIM-barrel-like domain zf-TRAF PF02176.18 RJW73498.1 - 0.00014 22.5 1.6 0.00014 22.5 1.6 3.3 3 1 0 3 3 3 1 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 RJW73498.1 - 0.00049 19.9 10.6 0.00049 19.9 10.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 RJW73498.1 - 0.00052 20.0 2.9 0.00098 19.1 2.9 1.4 1 0 0 1 1 1 1 Seven in absentia protein family zf-RING_4 PF14570.6 RJW73498.1 - 0.0093 15.7 9.9 0.0093 15.7 9.9 2.6 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 RJW73498.1 - 0.69 9.9 17.3 0.065 13.2 12.2 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_14 PF17978.1 RJW73498.1 - 0.85 10.1 7.0 0.49 10.8 3.5 2.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 RJW73498.1 - 1.2 9.0 15.4 0.064 13.1 9.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RJW73498.1 - 1.9 8.4 20.1 0.71 9.8 13.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HORMA PF02301.18 RJW73500.1 - 8.7e-30 103.9 0.8 1.7e-29 102.9 0.0 1.8 2 0 0 2 2 2 1 HORMA domain PHD PF00628.29 RJW73500.1 - 4.4e-08 32.9 6.9 8.3e-08 32.0 6.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RJW73500.1 - 0.00074 19.0 3.1 0.0014 18.1 3.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 RJW73500.1 - 0.89 10.0 4.8 2.8 8.4 4.8 2.0 1 1 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Tctex-1 PF03645.13 RJW73501.1 - 5.8e-08 32.9 1.2 1.8e-07 31.3 1.2 1.9 1 1 0 1 1 1 1 Tctex-1 family CUB PF00431.20 RJW73502.1 - 9.2e-55 183.7 0.4 4.4e-24 84.9 0.1 3.0 3 0 0 3 3 3 3 CUB domain CUB_2 PF02408.20 RJW73502.1 - 1.5e-08 34.4 0.2 0.0025 17.6 0.1 2.4 2 0 0 2 2 2 2 CUB-like domain IL4Ra_N PF09238.10 RJW73502.1 - 0.00018 21.7 0.0 0.25 11.7 0.0 2.3 2 0 0 2 2 2 2 Interleukin-4 receptor alpha chain, N-terminal LTD PF00932.19 RJW73502.1 - 0.0017 18.7 0.7 0.045 14.1 0.3 2.5 2 1 0 2 2 2 1 Lamin Tail Domain LNS2 PF08235.13 RJW73504.1 - 2.8e-96 321.4 0.0 4.2e-96 320.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 RJW73504.1 - 4.8e-31 106.7 0.0 1e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 RJW73504.1 - 2.1e-25 88.8 0.1 3.9e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain TadE PF07811.12 RJW73504.1 - 0.35 11.2 1.3 0.68 10.3 1.3 1.4 1 0 0 1 1 1 0 TadE-like protein TGF_beta PF00019.20 RJW73505.1 - 2.5e-23 83.0 0.8 5.6e-23 81.9 0.8 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Hydrophobin_2 PF06766.11 RJW73505.1 - 0.15 12.1 1.6 0.91 9.5 0.3 2.5 2 0 0 2 2 2 0 Fungal hydrophobin Med30 PF11315.8 RJW73506.1 - 8.8e-43 146.0 0.0 1e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 30 Syntaxin-6_N PF09177.11 RJW73506.1 - 0.039 14.5 0.4 2.8 8.6 0.2 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Bystin PF05291.11 RJW73507.1 - 2.3e-63 214.2 0.2 3.2e-63 213.8 0.2 1.1 1 0 0 1 1 1 1 Bystin CUB PF00431.20 RJW73508.1 - 9.8e-05 22.7 0.4 0.00015 22.0 0.4 1.6 1 1 0 1 1 1 1 CUB domain ANF_receptor PF01094.28 RJW73510.1 - 1.6e-41 142.6 0.0 2.3e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 RJW73510.1 - 5.4e-12 46.0 4.6 5.4e-12 46.0 4.6 2.1 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 RJW73510.1 - 1.4e-05 25.0 15.7 1.4e-05 25.0 15.7 3.2 2 1 1 3 3 3 1 Nine Cysteines Domain of family 3 GPCR DUF730 PF05325.11 RJW73510.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF730) Claudin_2 PF13903.6 RJW73510.1 - 0.02 14.6 0.9 0.036 13.8 0.9 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Peripla_BP_6 PF13458.6 RJW73510.1 - 0.2 11.3 0.0 0.42 10.2 0.0 1.4 2 0 0 2 2 2 0 Periplasmic binding protein Methyltransf_23 PF13489.6 RJW73511.1 - 2.2e-09 37.3 0.0 3.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RJW73511.1 - 4.5e-06 27.2 0.0 1e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RJW73511.1 - 0.0004 21.1 0.0 0.00089 20.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RJW73511.1 - 0.003 18.2 0.0 0.009 16.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RJW73511.1 - 0.005 16.6 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RJW73511.1 - 0.0065 15.8 0.0 0.0099 15.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 RJW73511.1 - 0.076 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CpcD PF01383.21 RJW73512.1 - 0.089 13.1 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain E1-E2_ATPase PF00122.20 RJW73513.1 - 8.3e-45 152.5 3.1 1.3e-44 151.9 1.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RJW73513.1 - 2e-33 115.7 0.0 2e-33 115.7 0.0 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 RJW73513.1 - 2.6e-23 81.9 0.0 5e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RJW73513.1 - 4.8e-20 72.7 0.0 9e-11 42.4 0.0 2.8 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RJW73513.1 - 9.2e-20 70.1 0.0 1.8e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RJW73513.1 - 2.5e-05 24.2 5.3 0.00074 19.3 0.5 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 RJW73513.1 - 0.048 14.1 0.1 0.44 10.9 0.1 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.32 RJW73515.1 - 5.2e-29 99.9 14.4 1.5e-06 28.8 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 RJW73515.1 - 9.5e-28 96.3 3.0 3.3e-27 94.5 0.3 3.1 2 1 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 RJW73515.1 - 0.00013 22.2 1.4 0.17 12.2 0.0 3.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Rib_hydrolayse PF02267.17 RJW73516.1 - 1.6e-63 214.3 0.4 2.1e-63 214.0 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase Utp21 PF04192.12 RJW73517.1 - 2e-22 79.9 0.2 4.7e-22 78.6 0.2 1.6 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 RJW73517.1 - 3.5e-07 30.8 10.3 0.48 11.4 0.2 7.7 8 0 0 8 8 8 3 WD domain, G-beta repeat Hira PF07569.11 RJW73517.1 - 0.29 10.8 1.5 0.86 9.3 0.1 2.5 4 1 0 4 4 4 0 TUP1-like enhancer of split 7tm_1 PF00001.21 RJW73518.1 - 4.3e-09 36.1 10.5 5.3e-09 35.8 10.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sulfotransfer_4 PF17784.1 RJW73519.1 - 7.1e-64 215.6 0.1 8.8e-64 215.3 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RJW73519.1 - 0.0064 16.9 1.4 0.027 14.9 0.3 2.4 1 1 0 2 2 2 1 Sulfotransferase family NS3_envE PF02723.14 RJW73519.1 - 0.36 10.9 4.1 0.89 9.7 4.1 1.6 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E MARVEL PF01284.23 RJW73521.1 - 1e-19 71.0 9.4 1.2e-19 70.7 9.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3938 PF13074.6 RJW73521.1 - 6.9 7.0 7.0 0.93 9.8 0.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3938) Sec16_C PF12931.7 RJW73522.1 - 1.2e-34 120.3 0.0 2.3e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 RJW73522.1 - 0.0026 18.4 0.0 0.012 16.2 0.0 2.2 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region RasGEF PF00617.19 RJW73523.1 - 3.6e-27 95.7 0.0 1.6e-26 93.6 0.0 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 RJW73523.1 - 4.8e-11 42.8 0.0 1.7e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif PH PF00169.29 RJW73523.1 - 0.099 13.2 0.0 26 5.4 0.0 2.5 2 0 0 2 2 2 0 PH domain Ion_trans PF00520.31 RJW73524.1 - 9.3e-26 90.5 56.7 3.9e-24 85.2 30.4 2.4 2 1 0 2 2 2 2 Ion transport protein Arc_PepC PF06819.11 RJW73525.1 - 0.018 15.1 0.3 0.048 13.8 0.3 1.6 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain DUF4294 PF14127.6 RJW73525.1 - 0.091 12.7 0.7 0.21 11.5 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) Tektin PF03148.14 RJW73525.1 - 0.097 11.4 11.1 9.1 4.9 10.1 2.8 1 1 0 1 1 1 0 Tektin family IFT57 PF10498.9 RJW73525.1 - 0.2 10.6 4.2 0.052 12.5 0.9 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TSNAXIP1_N PF15739.5 RJW73525.1 - 0.85 10.0 5.6 1.9 8.9 0.4 2.4 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Ins134_P3_kin PF05770.11 RJW73527.1 - 2.3e-37 128.5 0.1 5.8e-31 107.6 0.0 2.1 2 0 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain CR6_interact PF10147.9 RJW73528.1 - 4.6e-27 95.1 10.3 5.5e-27 94.8 10.3 1.1 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Tox-REase-5 PF15648.6 RJW73528.1 - 1.3 9.6 4.1 15 6.2 0.8 2.4 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 Tristanin_u2 PF16638.5 RJW73528.1 - 6.8 7.5 7.7 1.7 9.4 0.3 2.3 1 1 1 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers CLU PF13236.6 RJW73529.1 - 2.2e-84 282.7 0.0 3.8e-84 282.0 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 RJW73529.1 - 6.8e-51 172.8 0.0 1.2e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 RJW73529.1 - 8.2e-16 58.1 2.1 1e-09 38.5 0.2 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat CLU_N PF15044.6 RJW73529.1 - 1.8e-11 44.3 0.1 4e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 RJW73529.1 - 2e-07 30.7 0.4 0.15 12.0 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 RJW73529.1 - 3.8e-05 23.2 0.1 7.1e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 MalT-like TPR region DUF727 PF05303.12 RJW73529.1 - 0.00013 21.9 0.0 0.0007 19.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TPR_1 PF00515.28 RJW73529.1 - 0.019 14.8 0.0 0.38 10.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RJW73529.1 - 0.022 14.9 0.2 87 3.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 RJW73531.1 - 1.1e-10 41.3 0.0 1.8e-09 37.3 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RJW73531.1 - 1.2e-10 41.5 0.0 7.6e-10 38.9 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RJW73531.1 - 5.5e-09 37.0 0.3 1e-08 36.0 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RJW73531.1 - 1.4e-06 28.3 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RJW73531.1 - 0.0011 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 RJW73531.1 - 0.036 14.0 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.12 RJW73531.1 - 0.096 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PDZ PF00595.24 RJW73532.1 - 3.6e-05 24.0 0.0 7.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW73532.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Guanylate_cyc PF00211.20 RJW73533.1 - 7.2e-51 172.4 0.1 1.7e-50 171.2 0.1 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RJW73533.1 - 1e-45 155.9 5.4 1e-45 155.9 5.4 2.5 2 1 0 2 2 2 1 Heme NO binding associated HNOB PF07700.15 RJW73533.1 - 1.8e-45 154.8 1.8 6.7e-45 153.0 0.6 2.2 2 0 0 2 2 2 1 Haem-NO-binding Pkinase PF00069.25 RJW73534.1 - 1.6e-20 73.6 0.0 2.1e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PS_Dcarbxylase PF02666.15 RJW73535.1 - 2.4e-54 184.0 0.0 3.6e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Jnk-SapK_ap_N PF09744.9 RJW73536.1 - 6.3e-40 137.0 11.7 6.3e-40 137.0 11.7 2.5 2 1 0 2 2 2 1 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 RJW73536.1 - 3.5e-25 88.0 3.1 3.5e-25 88.0 3.1 2.9 4 0 0 4 4 4 1 JNK-interacting protein leucine zipper II HR1 PF02185.16 RJW73536.1 - 0.21 11.7 3.5 0.82 9.8 3.5 2.0 1 0 0 1 1 1 0 Hr1 repeat Mto2_bdg PF12808.7 RJW73536.1 - 0.67 10.3 4.3 5.3 7.4 0.5 3.3 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1902 PF08972.11 RJW73536.1 - 0.71 9.9 3.3 19 5.3 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) FliD_C PF07195.12 RJW73536.1 - 2.4 7.5 4.5 1.6 8.1 0.1 2.4 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF2205 PF10224.9 RJW73536.1 - 2.5 8.2 5.3 4.4 7.4 0.2 3.1 2 0 0 2 2 2 0 Short coiled-coil protein CENP-F_leu_zip PF10473.9 RJW73536.1 - 4.5 7.3 16.9 1 9.4 1.0 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 RJW73536.1 - 6.4 7.5 11.1 19 5.9 0.5 3.9 3 1 0 3 3 3 0 Initiation control protein YabA eRF1_1 PF03463.15 RJW73538.1 - 1.4e-45 154.5 0.9 2.5e-45 153.6 0.9 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 RJW73538.1 - 1.2e-29 103.3 0.1 2e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 RJW73538.1 - 1.2e-22 80.5 0.2 3.7e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 DUF1577 PF07614.11 RJW73539.1 - 0.0022 17.1 1.6 0.87 8.6 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1577) Peptidase_M1 PF01433.20 RJW73539.1 - 0.0026 17.4 0.1 1.9 8.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M1 domain SPATA48 PF15073.6 RJW73539.1 - 0.012 15.9 5.2 0.96 9.8 0.4 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 48 HTH_AraC PF00165.23 RJW73539.1 - 0.02 15.0 0.8 10 6.4 0.1 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Syntaxin-18_N PF10496.9 RJW73539.1 - 0.028 14.6 2.3 6.1 7.2 0.2 2.3 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Flavi_NS4B PF01349.17 RJW73539.1 - 0.059 12.8 0.2 9.4 5.5 0.0 2.1 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4B DUF4640 PF15480.6 RJW73539.1 - 0.063 13.0 3.5 0.56 9.9 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4640) DUF327 PF03885.13 RJW73539.1 - 0.53 10.2 2.3 22 5.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Trypsin PF00089.26 RJW73540.1 - 3.6e-55 187.2 0.0 1.6e-52 178.5 0.0 2.1 2 0 0 2 2 2 2 Trypsin Pkinase PF00069.25 RJW73541.1 - 1.3e-25 90.3 0.0 7.3e-24 84.5 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW73541.1 - 8.7e-15 54.7 0.1 1.7e-13 50.4 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RJW73541.1 - 5.2e-06 25.5 0.0 1.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RJW73541.1 - 0.00075 19.5 0.0 0.0066 16.4 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family RGS PF00615.19 RJW73543.1 - 3.5e-08 33.7 1.1 0.00031 21.0 0.0 3.3 3 1 0 3 3 3 2 Regulator of G protein signaling domain RGS-like PF09128.11 RJW73543.1 - 0.041 13.6 0.0 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain HNOBA PF07701.14 RJW73544.1 - 3.9e-49 167.1 3.1 3e-48 164.2 3.1 2.2 1 1 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 RJW73544.1 - 3.7e-43 147.3 0.0 6.8e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 RJW73544.1 - 9.6e-43 146.0 0.4 2.5e-42 144.6 0.1 1.8 2 0 0 2 2 2 1 Haem-NO-binding Dpy-30 PF05186.13 RJW73544.1 - 0.00085 19.0 0.0 0.0032 17.1 0.0 1.9 2 0 0 2 2 2 1 Dpy-30 motif RVT_1 PF00078.27 RJW73545.1 - 2.8e-41 141.5 0.0 7.7e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW73545.1 - 5.7e-07 29.4 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase WD40 PF00400.32 RJW73546.1 - 1.3e-09 38.5 5.2 0.0078 17.1 0.4 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73546.1 - 2.2e-05 24.7 0.1 0.00064 20.0 0.1 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4716 PF15837.5 RJW73546.1 - 0.13 12.3 0.3 0.3 11.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4716) WD40 PF00400.32 RJW73549.1 - 2.4e-22 78.8 12.8 0.0091 16.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73549.1 - 5.3e-05 23.4 0.2 1.1 9.6 0.0 3.8 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RJW73549.1 - 0.00028 19.7 5.7 0.45 9.1 0.2 4.3 1 1 3 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 RJW73549.1 - 0.0046 16.9 0.1 0.9 9.4 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A FlaC_arch PF05377.11 RJW73552.1 - 0.7 10.3 0.1 0.7 10.3 0.1 2.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Pro_CA PF00484.19 RJW73552.1 - 3.2 8.0 5.0 7.9 6.8 5.0 1.7 1 0 0 1 1 1 0 Carbonic anhydrase TMF_DNA_bd PF12329.8 RJW73552.1 - 4.7 7.3 31.8 0.63 10.1 11.2 3.8 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding PB1 PF00564.24 RJW73553.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 PB1 domain WD40_3 PF15911.5 RJW73556.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 WD domain, G-beta repeat Polyketide_cyc2 PF10604.9 RJW73557.1 - 1.5e-07 31.7 0.0 2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 RJW73557.1 - 0.0019 18.4 0.0 0.0078 16.4 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 RJW73557.1 - 0.025 14.8 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein zf-C3H2C3 PF17122.5 RJW73558.1 - 0.031 14.3 2.9 0.031 14.3 2.9 2.3 2 0 0 2 2 2 0 Zinc-finger RVT_1 PF00078.27 RJW73559.1 - 2.3e-32 112.3 0.1 3.7e-32 111.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_4 PF13637.6 RJW73559.1 - 5.6e-16 58.7 1.4 1.9e-08 34.7 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RJW73559.1 - 6.9e-13 49.0 0.1 6.7e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RJW73559.1 - 3.9e-11 42.1 0.0 0.0093 16.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RJW73559.1 - 5.5e-11 42.4 0.5 0.00037 20.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RJW73559.1 - 2.1e-08 34.3 0.1 0.0016 18.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Elf1 PF05129.13 RJW73560.1 - 0.15 12.2 1.5 0.84 9.7 0.4 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DSL PF01414.19 RJW73561.1 - 3.8e-07 30.3 3.6 3.8e-07 30.3 3.6 2.5 1 1 1 2 2 2 1 Delta serrate ligand EGF PF00008.27 RJW73561.1 - 0.011 16.1 3.0 0.011 16.1 3.0 2.4 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.7 RJW73561.1 - 0.015 15.9 2.0 0.015 15.9 2.0 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF DUF2207 PF09972.9 RJW73561.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FXa_inhibition PF14670.6 RJW73561.1 - 0.33 11.3 6.5 2.7 8.4 2.2 2.5 1 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 RJW73561.1 - 0.66 10.4 12.3 0.16 12.4 5.9 2.7 2 1 0 2 2 2 0 EGF-like domain SH3_10 PF17902.1 RJW73562.1 - 7.6e-05 22.7 0.0 0.34 11.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain Plk4_PB2 PF18409.1 RJW73562.1 - 0.097 13.4 0.1 0.29 11.8 0.1 1.8 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 CCDC-167 PF15188.6 RJW73562.1 - 7.9 6.9 7.0 0.47 10.8 0.9 2.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 RPA_interact_C PF14768.6 RJW73565.1 - 8.5e-18 64.7 6.2 2.1e-17 63.5 6.2 1.7 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Na_K-ATPase PF00287.18 RJW73569.1 - 1.3e-40 139.4 0.8 1.7e-40 139.0 0.8 1.1 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Orf78 PF06024.12 RJW73569.1 - 0.13 12.5 0.4 0.22 11.8 0.4 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Dynein_light PF01221.18 RJW73572.1 - 4.3e-36 123.1 1.8 4.7e-36 123.0 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3546 PF12066.8 RJW73573.1 - 1.3e-38 131.5 0.8 2.8e-38 130.5 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 RJW73573.1 - 7.5e-31 108.0 7.9 2.8e-30 106.2 7.9 1.9 1 1 0 1 1 1 1 Arsenite-resistance protein 2 GRP PF07172.11 RJW73573.1 - 3.8 8.3 13.6 15 6.3 13.6 2.0 1 0 0 1 1 1 0 Glycine rich protein family RVT_1 PF00078.27 RJW73574.1 - 9.4e-06 25.3 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lipoprotein_18 PF06804.11 RJW73575.1 - 0.071 12.1 0.2 0.82 8.7 0.0 2.0 2 0 0 2 2 2 0 NlpB/DapX lipoprotein 5_nucleotid PF05761.14 RJW73576.1 - 2.3e-136 455.3 2.5 2.8e-136 455.1 2.5 1.1 1 0 0 1 1 1 1 5' nucleotidase family RVT_1 PF00078.27 RJW73576.1 - 3.4e-17 62.7 0.0 9e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Got1 PF04178.12 RJW73577.1 - 4.2e-12 46.5 2.1 6.2e-12 45.9 2.1 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4200 PF13863.6 RJW73578.1 - 1.1e-18 67.8 9.1 1.1e-18 67.8 9.1 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4200) CoA_binding_2 PF13380.6 RJW73578.1 - 0.022 15.3 0.4 1.9 9.0 0.0 3.0 3 0 0 3 3 3 0 CoA binding domain NPV_P10 PF05531.12 RJW73578.1 - 0.047 14.2 0.6 0.75 10.3 0.0 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.19 RJW73578.1 - 4.9 4.9 12.0 40 1.9 11.9 2.2 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family PAPS_reduct PF01507.19 RJW73580.1 - 3e-31 108.8 0.0 4.6e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 RJW73580.1 - 1.6e-27 95.9 0.0 3.4e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAC2 PF09754.9 RJW73581.1 - 3.3e-23 82.8 0.0 4e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 PAC2 family AAA PF00004.29 RJW73582.1 - 2.4e-40 138.0 0.0 4.9e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 RJW73582.1 - 1.1e-21 76.7 0.0 2.4e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 RJW73582.1 - 1.7e-09 37.3 0.0 4.7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 RJW73582.1 - 7.6e-05 22.9 0.0 0.00017 21.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RJW73582.1 - 0.00011 22.5 0.0 0.001 19.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RJW73582.1 - 0.00067 20.1 2.1 0.011 16.2 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 RJW73582.1 - 0.001 19.3 0.1 0.004 17.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 RJW73582.1 - 0.0024 17.6 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 RJW73582.1 - 0.0031 17.5 0.0 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RJW73582.1 - 0.0073 15.7 0.1 0.025 14.0 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RJW73582.1 - 0.008 16.7 0.0 0.023 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RJW73582.1 - 0.028 14.2 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RJW73582.1 - 0.031 14.7 0.0 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Parvo_NS1 PF01057.17 RJW73582.1 - 0.039 13.0 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 RJW73582.1 - 0.077 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain 7tm_1 PF00001.21 RJW73583.1 - 6.6e-31 107.6 14.9 6.6e-31 107.6 14.9 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RJW73583.1 - 1.3e-05 25.0 5.1 1.3e-05 25.0 5.1 2.7 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RJW73583.1 - 0.0087 15.4 0.1 0.0087 15.4 0.1 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw LRR19-TM PF15176.6 RJW73583.1 - 0.13 12.3 1.8 4.5 7.3 0.1 2.7 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain PNK3P PF08645.11 RJW73584.1 - 7.5e-53 178.6 0.0 1.2e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 RJW73584.1 - 1.4e-15 57.7 0.4 2.3e-06 27.8 0.2 3.0 2 1 1 3 3 3 2 AAA domain Zeta_toxin PF06414.12 RJW73584.1 - 2e-05 24.0 0.1 0.028 13.7 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin Hydrolase_6 PF13344.6 RJW73584.1 - 0.011 15.8 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase 6PF2K PF01591.18 RJW73584.1 - 0.015 14.6 0.2 0.14 11.4 0.0 2.0 1 1 0 2 2 2 0 6-phosphofructo-2-kinase FAD_binding_2 PF00890.24 RJW73584.1 - 0.057 12.5 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HAD PF12710.7 RJW73584.1 - 0.078 13.4 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 RJW73584.1 - 0.099 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 RJW73584.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fascin PF06268.13 RJW73585.1 - 3.8e-32 110.8 0.0 2.7e-15 56.6 0.0 5.7 6 1 1 7 7 7 4 Fascin domain FRG1 PF06229.12 RJW73585.1 - 2.4e-06 27.4 0.0 0.0054 16.5 0.0 3.4 3 0 0 3 3 3 2 FRG1-like domain PfkB PF00294.24 RJW73586.1 - 1e-53 182.6 0.0 1.3e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ran_BP1 PF00638.18 RJW73587.1 - 5.9e-86 284.9 0.4 2.1e-30 105.5 0.0 5.4 4 1 0 4 4 4 4 RanBP1 domain zf-RanBP PF00641.18 RJW73587.1 - 3.3e-11 42.3 15.5 2.3e-08 33.2 3.8 2.8 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others WH1 PF00568.23 RJW73587.1 - 2.5e-05 24.2 0.1 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 1 WH1 domain Spc7 PF08317.11 RJW73587.1 - 0.055 12.3 3.8 0.093 11.6 3.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Lig_C PF18330.1 RJW73587.1 - 0.12 12.4 0.0 48 4.0 0.0 3.3 3 0 0 3 3 3 0 Ligase Pab1020 C-terminal region TPR_16 PF13432.6 RJW73587.1 - 0.14 12.8 0.2 12 6.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Synaptobrevin PF00957.21 RJW73587.1 - 0.16 11.8 2.3 0.32 10.8 2.3 1.5 1 0 0 1 1 1 0 Synaptobrevin PMC2NT PF08066.12 RJW73587.1 - 0.17 12.6 1.5 0.6 10.8 1.5 1.9 1 0 0 1 1 1 0 PMC2NT (NUC016) domain FemAB PF02388.16 RJW73587.1 - 0.3 9.9 0.9 0.51 9.2 0.9 1.2 1 0 0 1 1 1 0 FemAB family BNIP2 PF12496.8 RJW73587.1 - 0.62 10.5 7.2 0.44 11.0 1.0 3.4 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DZR PF12773.7 RJW73587.1 - 1.4 9.0 7.7 8.6 6.5 7.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon KxDL PF10241.9 RJW73587.1 - 1.7 9.0 4.5 4.7 7.6 4.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein NUDIX PF00293.28 RJW73588.1 - 7.3e-08 32.5 0.0 2e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain SPOC PF07744.13 RJW73589.1 - 2e-37 128.4 0.0 4.3e-37 127.3 0.0 1.6 2 0 0 2 2 2 1 SPOC domain RRM_1 PF00076.22 RJW73589.1 - 2e-21 75.6 0.0 1.8e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW73589.1 - 0.026 14.6 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif Syntaxin PF00804.25 RJW73592.1 - 1.7e-46 158.4 14.2 2.8e-46 157.7 14.2 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 RJW73592.1 - 2.6e-09 36.9 0.4 2.6e-09 36.9 0.4 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 RJW73592.1 - 4.5e-06 27.0 3.2 4.5e-06 27.0 3.2 3.1 3 0 0 3 3 3 1 Syntaxin-like protein Syntaxin-6_N PF09177.11 RJW73592.1 - 0.0061 17.1 4.9 0.024 15.2 3.7 2.5 1 1 1 2 2 2 1 Syntaxin 6, N-terminal FlaC_arch PF05377.11 RJW73592.1 - 0.31 11.5 4.3 21 5.6 0.0 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 RJW73592.1 - 0.39 11.0 6.8 4 7.8 1.1 3.2 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 RJW73592.1 - 0.86 10.1 5.2 12 6.5 1.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 RJW73592.1 - 1.2 7.6 10.0 0.23 9.9 3.5 2.0 1 1 0 2 2 2 0 Fusaric acid resistance protein family DUF848 PF05852.11 RJW73592.1 - 1.2 9.2 12.4 0.15 12.1 3.2 2.5 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) YtxH PF12732.7 RJW73592.1 - 2.4 8.7 4.4 2.6 8.7 0.3 2.6 2 0 0 2 2 2 0 YtxH-like protein BLOC1_2 PF10046.9 RJW73592.1 - 3.9 7.8 11.7 19 5.6 0.0 3.8 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1003 PF06210.11 RJW73592.1 - 7.5 6.7 8.5 11 6.2 2.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) RVT_1 PF00078.27 RJW73594.1 - 3.3e-35 121.6 0.0 9e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA_Me_trans PF03054.16 RJW73595.1 - 4.6e-87 292.1 0.0 1.7e-80 270.5 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase Lipocalin PF00061.23 RJW73596.1 - 7.9e-22 78.0 3.9 8.7e-22 77.9 3.9 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 RJW73596.1 - 9e-06 25.7 1.5 1.3e-05 25.2 1.5 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family TMEM72 PF16054.5 RJW73596.1 - 0.063 13.0 0.1 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein family 72 DUF1233 PF06806.12 RJW73596.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative excisionase (DUF1233) Cadherin PF00028.17 RJW73597.1 - 6.6e-47 157.9 4.4 1.2e-11 44.8 0.3 10.8 10 1 1 11 11 11 6 Cadherin domain Cadherin_2 PF08266.12 RJW73597.1 - 0.00087 19.1 0.0 13 5.7 0.0 3.8 3 0 0 3 3 3 2 Cadherin-like SLD5_C PF16922.5 RJW73599.1 - 1.5e-13 50.7 0.0 3.5e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 RJW73599.1 - 1.4e-05 25.5 0.3 2.1e-05 24.9 0.3 1.4 1 0 0 1 1 1 1 GINS complex protein CRR7 PF12095.8 RJW73599.1 - 0.088 13.3 1.0 11 6.5 0.4 2.7 2 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 ABC_tran PF00005.27 RJW73600.1 - 1.6e-65 219.8 0.0 2.5e-34 118.8 0.0 2.6 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 RJW73600.1 - 2.8e-53 181.3 7.8 4.6e-53 180.6 7.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RJW73600.1 - 4.5e-14 52.4 0.8 0.0016 17.9 0.0 4.7 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RJW73600.1 - 2e-12 47.6 0.3 6.7e-05 23.2 0.0 3.5 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RJW73600.1 - 2e-09 37.5 0.0 0.00063 19.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RJW73600.1 - 1.2e-08 35.5 2.4 0.00054 20.4 0.3 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RJW73600.1 - 1.1e-06 28.3 0.0 0.034 13.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 RJW73600.1 - 1.4e-06 28.9 0.0 0.03 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 RJW73600.1 - 1.6e-06 28.1 0.0 0.12 12.2 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 RJW73600.1 - 3e-06 26.6 0.0 0.059 12.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.14 RJW73600.1 - 3.1e-06 27.2 0.0 0.2 11.7 0.0 4.1 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) Rad17 PF03215.15 RJW73600.1 - 3.3e-06 27.1 0.1 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_30 PF13604.6 RJW73600.1 - 1.2e-05 25.1 0.2 0.1 12.3 0.1 3.8 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 RJW73600.1 - 7.6e-05 23.1 1.1 0.68 10.4 0.1 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 RJW73600.1 - 0.0001 22.9 0.0 0.49 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 RJW73600.1 - 0.00011 21.8 0.1 0.12 11.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 RJW73600.1 - 0.00016 21.7 0.0 0.78 9.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 RJW73600.1 - 0.00032 20.3 0.1 3 7.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 RJW73600.1 - 0.00041 20.2 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 RJW73600.1 - 0.00041 20.1 0.1 1.7 8.3 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 RJW73600.1 - 0.00043 19.6 0.0 0.091 12.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin tRNA_lig_kinase PF08303.11 RJW73600.1 - 0.00045 20.3 0.2 0.9 9.6 0.0 2.9 3 0 0 3 3 2 1 tRNA ligase kinase domain RNA_helicase PF00910.22 RJW73600.1 - 0.00065 20.1 0.0 0.94 9.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 RJW73600.1 - 0.0007 19.8 0.1 2.3 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 RJW73600.1 - 0.00083 18.6 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TniB PF05621.11 RJW73600.1 - 0.00084 18.8 0.0 16 4.8 0.0 4.0 4 0 0 4 4 4 0 Bacterial TniB protein SbcCD_C PF13558.6 RJW73600.1 - 0.00094 19.4 4.1 0.21 11.9 0.2 3.7 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit FeoB_N PF02421.18 RJW73600.1 - 0.0015 18.1 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B PRK PF00485.18 RJW73600.1 - 0.0018 18.0 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 RJW73600.1 - 0.002 18.2 0.0 0.68 10.0 0.0 3.4 3 1 1 4 4 3 1 AAA domain AAA_28 PF13521.6 RJW73600.1 - 0.0025 18.1 0.3 0.69 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RJW73600.1 - 0.0025 17.7 0.0 3.9 7.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain DEAD PF00270.29 RJW73600.1 - 0.0027 17.5 0.1 2.9 7.6 0.0 3.3 2 2 0 2 2 2 1 DEAD/DEAH box helicase ABC_ATPase PF09818.9 RJW73600.1 - 0.0048 15.7 0.4 3.1 6.5 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_24 PF13479.6 RJW73600.1 - 0.014 15.1 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RJW73600.1 - 0.015 15.0 0.0 8.4 6.1 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.13 RJW73600.1 - 0.016 14.3 0.0 5.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 RJW73600.1 - 0.049 13.3 0.0 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.14 RJW73600.1 - 0.05 12.8 0.0 3.3 6.9 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain DUF4396 PF14342.6 RJW73600.1 - 0.063 13.6 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) AAA_17 PF13207.6 RJW73600.1 - 0.063 13.7 0.1 8.5 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 RJW73600.1 - 0.097 12.4 0.0 7.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase APS_kinase PF01583.20 RJW73600.1 - 0.12 12.3 0.0 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase dNK PF01712.19 RJW73600.1 - 0.14 12.0 0.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase SRPRB PF09439.10 RJW73600.1 - 0.15 11.5 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Sigma54_activ_2 PF14532.6 RJW73600.1 - 0.15 12.1 0.0 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Dynamin_N PF00350.23 RJW73600.1 - 0.2 11.7 0.3 5 7.1 0.0 2.5 2 0 0 2 2 2 0 Dynamin family NDUF_B6 PF09782.9 RJW73601.1 - 0.13 12.4 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF21 PF01595.20 RJW73602.1 - 2.1e-33 115.5 1.9 3.6e-33 114.7 1.9 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 RJW73602.1 - 2e-05 24.9 0.3 0.00016 22.0 0.0 2.7 3 0 0 3 3 3 1 CBS domain PRKCSH PF07915.13 RJW73603.1 - 3e-19 69.8 17.6 9.8e-12 45.7 3.1 3.9 3 1 0 3 3 3 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 RJW73603.1 - 3.2e-12 46.4 5.5 2.9e-06 27.1 1.9 2.6 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein Ank_2 PF12796.7 RJW73604.1 - 9.4e-26 90.2 2.7 8.5e-12 45.5 0.1 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RJW73604.1 - 5.6e-24 83.9 10.4 3.6e-08 33.5 0.6 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RJW73604.1 - 1e-22 79.5 8.5 2.3e-05 24.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 RJW73604.1 - 7.1e-21 74.3 7.7 8.9e-05 23.0 1.2 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW73604.1 - 1.8e-17 61.7 9.0 9.9e-05 22.5 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat PAX PF00292.18 RJW73605.1 - 6e-35 119.9 0.6 1.2e-34 118.9 0.6 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 RJW73605.1 - 3.8e-07 29.7 0.0 1.1e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 RJW73605.1 - 0.00017 21.6 0.0 0.00039 20.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 RJW73605.1 - 0.0025 17.8 0.1 0.0055 16.7 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix Homeodomain PF00046.29 RJW73605.1 - 0.026 14.4 0.5 0.026 14.4 0.5 2.6 2 0 0 2 2 2 0 Homeodomain HTH_38 PF13936.6 RJW73605.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain EMC3_TMCO1 PF01956.16 RJW73605.1 - 0.8 9.4 14.7 0.5 10.1 12.3 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Cadherin PF00028.17 RJW73606.1 - 1.8e-67 223.8 10.0 1.3e-17 64.1 0.1 8.8 8 2 0 8 8 8 6 Cadherin domain Cadherin_2 PF08266.12 RJW73606.1 - 4.3e-10 39.3 0.4 0.0021 17.8 0.3 5.6 4 1 0 4 4 4 3 Cadherin-like Cadherin_3 PF16184.5 RJW73606.1 - 2.8e-05 24.1 12.5 0.35 10.9 0.0 6.4 7 1 0 7 7 7 3 Cadherin-like DFP PF04127.15 RJW73607.1 - 3.2e-12 46.6 0.0 3.5e-06 27.0 0.0 2.5 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein UPF0061 PF02696.14 RJW73608.1 - 6.9e-117 391.1 0.0 6.7e-116 387.8 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family UPF0506 PF11703.8 RJW73609.1 - 1.9e-20 73.0 18.7 2.5e-20 72.6 18.7 1.2 1 0 0 1 1 1 1 UPF0506 Conotoxin PF02950.17 RJW73609.1 - 0.0045 18.0 18.6 0.18 12.9 8.1 2.2 1 1 1 2 2 2 2 Conotoxin Conotoxin_I2 PF17557.2 RJW73609.1 - 0.017 15.3 5.7 0.017 15.3 5.7 2.6 2 1 0 2 2 2 0 I2-superfamily conotoxins Toxin_21 PF08091.11 RJW73609.1 - 0.056 13.4 3.1 0.056 13.4 3.1 3.3 2 2 1 3 3 3 0 Spider insecticidal peptide Mtc PF03820.17 RJW73609.1 - 0.25 10.3 0.0 0.29 10.2 0.0 1.0 1 0 0 1 1 1 0 Tricarboxylate carrier Toxin_30 PF08117.11 RJW73609.1 - 0.38 11.0 14.7 3.7 7.9 0.8 2.6 1 1 1 2 2 2 0 Ptu family Stig1 PF04885.13 RJW73609.1 - 0.5 10.8 15.1 0.63 10.5 15.1 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Dickkopf_N PF04706.12 RJW73609.1 - 0.53 10.8 19.3 0.61 10.6 10.7 2.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Cpn60_TCP1 PF00118.24 RJW73611.1 - 1.3e-150 502.3 10.3 1.5e-150 502.1 10.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Band_7 PF01145.25 RJW73613.1 - 2.2e-32 112.5 0.6 2.8e-32 112.1 0.6 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 RJW73613.1 - 0.0011 18.8 0.1 0.0018 18.1 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 RJW73613.1 - 0.064 13.7 0.2 0.16 12.4 0.2 1.6 1 0 0 1 1 1 0 Phage protein Gp68 Mito_carr PF00153.27 RJW73615.1 - 6.4e-57 189.5 0.4 3.4e-20 71.8 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein CH PF00307.31 RJW73616.1 - 8.7e-68 225.4 0.0 3.2e-20 72.3 0.1 4.6 4 0 0 4 4 4 4 Calponin homology (CH) domain RVT_1 PF00078.27 RJW73616.1 - 7.8e-08 32.1 0.3 2.7e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CH_2 PF06294.11 RJW73616.1 - 0.0022 18.1 0.1 0.082 13.0 0.0 3.2 3 0 0 3 3 3 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 RJW73616.1 - 0.012 15.5 0.0 0.38 10.6 0.1 3.0 3 0 0 3 3 3 0 CAMSAP CH domain GIY-YIG PF01541.24 RJW73616.1 - 0.021 15.1 0.1 0.065 13.5 0.1 1.8 1 0 0 1 1 1 0 GIY-YIG catalytic domain CBM_21 PF03370.13 RJW73617.1 - 3.5e-20 72.2 0.1 5.7e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 RJW73617.1 - 2.1e-11 44.3 0.2 3.8e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) zf-AD PF07776.15 RJW73619.1 - 0.01 16.0 0.0 0.064 13.5 0.0 2.4 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) FOXP-CC PF16159.5 RJW73619.1 - 0.036 14.7 0.8 0.036 14.7 0.8 7.7 7 3 2 9 9 9 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 RJW73619.1 - 0.12 12.5 8.5 5.9 7.0 0.2 4.0 3 0 0 3 3 3 0 Aberrant zinc-finger zf_C2H2_ZHX PF18387.1 RJW73619.1 - 4.4 7.0 19.4 13 5.5 0.4 5.7 3 2 2 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain Armet PF10208.9 RJW73621.1 - 1.9e-33 115.4 4.4 2.4e-33 115.1 4.4 1.1 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Tetraspanin PF00335.20 RJW73623.1 - 2e-05 24.4 2.8 2.5e-05 24.1 2.8 1.2 1 0 0 1 1 1 1 Tetraspanin family COX2-transmemb PF09125.10 RJW73623.1 - 2.7 7.9 4.9 0.33 10.8 0.5 1.8 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane TPR_2 PF07719.17 RJW73624.1 - 8e-13 47.4 2.9 0.00084 19.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RJW73624.1 - 5.8e-10 38.6 3.7 0.0027 17.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 RJW73624.1 - 1.1e-08 35.4 2.7 4.2e-07 30.4 0.2 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW73624.1 - 1.2e-08 35.1 5.5 0.00021 21.4 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RJW73624.1 - 9e-08 32.0 2.4 0.00025 21.2 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW73624.1 - 1.8e-07 31.7 1.1 4.1e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RJW73624.1 - 9.3e-06 25.7 1.3 0.00057 20.0 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RJW73624.1 - 2.7e-05 24.0 2.2 0.97 9.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RJW73624.1 - 6e-05 23.5 2.2 0.018 15.8 0.2 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 RJW73624.1 - 0.0001 22.6 2.2 0.00013 22.2 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 RJW73624.1 - 0.00021 21.6 0.5 0.023 15.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RJW73624.1 - 0.0011 19.2 6.2 0.026 14.8 1.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW73624.1 - 0.0076 16.2 4.0 0.079 13.0 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat NatB_MDM20 PF09797.9 RJW73624.1 - 0.0084 15.1 0.3 0.015 14.3 0.3 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_6 PF13174.6 RJW73624.1 - 0.01 16.4 7.5 0.025 15.2 0.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 RJW73624.1 - 0.014 15.4 3.2 3.1 7.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 RJW73624.1 - 0.016 14.8 6.6 0.045 13.4 0.5 3.5 2 2 1 3 3 3 0 TPR repeat TPR_15 PF13429.6 RJW73624.1 - 0.017 14.3 1.1 0.22 10.7 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 RJW73624.1 - 0.02 13.9 0.1 0.39 9.6 0.0 2.1 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 RJW73624.1 - 0.032 14.1 1.4 2.6 8.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5113 PF17140.4 RJW73624.1 - 0.068 13.0 1.0 0.22 11.3 0.6 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF5113) GLTSCR1 PF15249.6 RJW73626.1 - 0.0025 18.2 1.1 0.0066 16.9 1.1 1.7 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein E3_UbLigase_EDD PF11547.8 RJW73628.1 - 9.6e-31 105.2 2.3 9.6e-31 105.2 2.3 2.0 2 0 0 2 2 2 1 E3 ubiquitin ligase EDD HECT PF00632.25 RJW73628.1 - 2e-18 66.9 0.0 3.3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PABP PF00658.18 RJW73628.1 - 6.9e-10 39.0 0.0 2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain zf-UBR PF02207.20 RJW73628.1 - 0.014 15.5 21.1 0.029 14.5 21.1 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) TFIIF_alpha PF05793.12 RJW73628.1 - 0.33 9.5 30.2 0.87 8.1 30.2 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 RJW73628.1 - 0.59 9.5 24.8 1.1 8.6 24.8 1.4 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 RJW73628.1 - 1.1 8.4 35.7 3.2 6.8 35.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 RJW73628.1 - 2.5 6.3 15.6 4.8 5.4 15.6 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 RJW73628.1 - 4.6 6.5 29.5 11 5.2 29.5 1.6 1 0 0 1 1 1 0 BUD22 RVT_1 PF00078.27 RJW73631.1 - 1.2e-46 159.1 0.5 5.8e-46 156.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW73631.1 - 4.8e-12 45.8 0.0 3e-11 43.2 0.0 2.4 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Nop53 PF07767.11 RJW73631.1 - 0.0017 17.9 5.2 0.0017 17.9 5.2 2.0 2 1 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) SIKE PF05769.11 RJW73633.1 - 2.3e-27 96.1 3.0 5.5e-27 94.8 3.0 1.6 1 1 0 1 1 1 1 SIKE family NUDE_C PF04880.13 RJW73633.1 - 0.0011 19.4 0.5 0.024 15.1 0.0 2.3 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region Herpes_BLRF2 PF05812.12 RJW73633.1 - 0.0056 16.8 0.1 1.6 8.9 0.0 2.8 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein PRKG1_interact PF15898.5 RJW73633.1 - 0.032 15.1 3.0 0.43 11.5 1.0 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Nas2_N PF18265.1 RJW73633.1 - 0.081 12.8 0.2 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Nas2 N_terminal domain FlaC_arch PF05377.11 RJW73633.1 - 0.11 13.0 5.7 0.78 10.2 0.3 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 RJW73633.1 - 0.13 12.6 2.6 0.56 10.5 0.0 2.7 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF2388 PF09498.10 RJW73633.1 - 0.13 12.2 0.9 0.86 9.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2388) P4Ha_N PF08336.11 RJW73633.1 - 0.14 12.2 0.7 9.6 6.2 0.0 2.7 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF5621 PF18532.1 RJW73633.1 - 0.25 11.2 1.1 22 4.9 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF5621) bZIP_1 PF00170.21 RJW73633.1 - 0.35 11.0 1.8 7.5 6.7 0.0 3.1 3 1 0 3 3 3 0 bZIP transcription factor MscS_porin PF12795.7 RJW73633.1 - 0.53 9.8 3.5 0.33 10.5 0.7 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF3450 PF11932.8 RJW73633.1 - 5 6.3 7.8 0.62 9.3 1.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Vma12 PF11712.8 RJW73634.1 - 2.2e-22 79.6 0.0 2.8e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4382 PF14321.6 RJW73636.1 - 0.026 14.8 0.0 0.031 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) PB1 PF00564.24 RJW73637.1 - 0.071 13.0 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 PB1 domain PilO PF04350.13 RJW73637.1 - 0.17 12.0 0.0 1.4 9.1 0.0 2.0 2 0 0 2 2 2 0 Pilus assembly protein, PilO RhoGEF PF00621.20 RJW73639.1 - 5.7e-28 98.4 1.9 5.7e-28 98.4 1.9 1.8 1 1 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 RJW73639.1 - 5.3e-16 58.0 0.4 1.4e-07 31.0 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 RJW73639.1 - 7.6e-15 54.3 0.0 3.3e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 RJW73639.1 - 8.9e-15 54.3 0.3 4.4e-07 29.7 0.0 3.1 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 RJW73639.1 - 3.2e-13 49.6 0.0 9.4e-13 48.1 0.0 1.9 1 0 0 1 1 1 1 SH2 domain CH PF00307.31 RJW73639.1 - 5.1e-13 49.2 0.0 9.7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain C1_1 PF00130.22 RJW73639.1 - 7e-09 35.4 2.6 1.9e-08 34.1 2.6 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 RJW73639.1 - 1.3e-08 35.2 0.0 3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 PH domain CAMSAP_CH PF11971.8 RJW73639.1 - 1.9e-07 30.8 0.2 4.7e-07 29.6 0.2 1.7 1 0 0 1 1 1 1 CAMSAP CH domain KxDL PF10241.9 RJW73639.1 - 0.16 12.2 0.6 3.9 7.8 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein C1_2 PF03107.16 RJW73639.1 - 0.22 11.9 4.0 0.54 10.6 4.0 1.7 1 0 0 1 1 1 0 C1 domain Cwf_Cwc_15 PF04889.12 RJW73641.1 - 1e-79 267.7 11.3 1.2e-79 267.5 11.3 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein VIR_N PF15912.5 RJW73641.1 - 0.12 11.9 5.0 0.2 11.2 5.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal NOA36 PF06524.12 RJW73641.1 - 0.49 9.7 7.4 0.84 8.9 7.4 1.4 1 0 0 1 1 1 0 NOA36 protein SURF2 PF05477.11 RJW73641.1 - 0.6 9.8 6.2 0.99 9.0 6.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Roughex PF06020.11 RJW73641.1 - 0.91 8.6 7.4 1.3 8.0 7.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein BSP_II PF05432.11 RJW73641.1 - 2.3 7.8 11.5 3.6 7.2 11.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TT_ORF2 PF02957.15 RJW73641.1 - 6.1 7.8 10.9 8.2 7.4 9.6 1.8 1 1 0 1 1 1 0 TT viral ORF2 WBP-1 PF11669.8 RJW73642.1 - 0.15 12.7 2.8 1.6 9.4 0.1 2.7 3 1 0 3 3 3 0 WW domain-binding protein 1 NTS_2 PF15448.6 RJW73643.1 - 0.0035 17.7 0.0 5.3 7.5 0.0 2.4 2 0 0 2 2 2 2 N-terminal segments of P. falciparum erythrocyte membrane protein ACDC PF14733.6 RJW73643.1 - 0.17 12.2 1.0 0.41 11.0 0.1 2.2 2 1 0 2 2 2 0 AP2-coincident C-terminal Adaptin_N PF01602.20 RJW73645.1 - 1.7e-151 505.4 11.9 2.1e-151 505.1 11.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RJW73645.1 - 1.5e-61 207.2 9.4 5e-60 202.2 0.8 3.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 RJW73645.1 - 5.4e-33 113.4 0.0 2.2e-32 111.5 0.1 2.1 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 RJW73645.1 - 2.3e-17 63.2 7.0 3e-06 27.5 0.2 5.8 2 2 4 6 6 6 4 HEAT repeats Alpha_adaptinC2 PF02883.20 RJW73645.1 - 4.4e-13 49.5 1.0 9.8e-13 48.4 0.3 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.22 RJW73645.1 - 1.9e-11 43.2 7.7 0.0077 16.4 0.1 6.3 5 0 0 5 5 5 3 HEAT repeat Cnd3 PF12719.7 RJW73645.1 - 2e-07 30.5 2.3 5.3e-05 22.6 0.1 3.0 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 RJW73645.1 - 0.00028 20.8 6.7 0.62 10.2 0.1 5.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 RJW73645.1 - 0.00034 20.2 1.0 0.39 10.2 0.2 3.3 2 2 0 2 2 2 2 CLASP N terminal AP3B1_C PF14796.6 RJW73645.1 - 0.00035 20.9 0.0 0.00086 19.6 0.0 1.7 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Mo25 PF08569.11 RJW73645.1 - 0.0016 17.8 0.7 0.12 11.7 0.0 2.5 1 1 0 2 2 2 1 Mo25-like HEAT_EZ PF13513.6 RJW73645.1 - 0.003 18.0 4.9 11 6.6 0.0 5.8 6 0 0 6 6 6 0 HEAT-like repeat Sec7_N PF12783.7 RJW73645.1 - 0.0041 17.0 4.6 0.0056 16.6 1.5 2.9 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TIP120 PF08623.10 RJW73645.1 - 0.028 14.2 8.6 8 6.2 0.2 4.5 4 1 0 4 4 4 0 TATA-binding protein interacting (TIP20) DNA_alkylation PF08713.11 RJW73645.1 - 0.045 13.4 0.0 0.36 10.5 0.0 2.3 2 1 0 2 2 2 0 DNA alkylation repair enzyme API5 PF05918.11 RJW73645.1 - 0.94 8.2 4.9 0.32 9.8 0.1 2.5 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) LisH PF08513.11 RJW73646.1 - 0.00024 20.9 0.5 0.11 12.4 0.0 2.9 3 0 0 3 3 3 2 LisH FYVE PF01363.21 RJW73647.1 - 6.9e-10 38.9 4.4 6.9e-10 38.9 4.4 3.4 3 1 0 3 3 3 1 FYVE zinc finger zf-C2H2_9 PF16293.5 RJW73647.1 - 0.016 15.1 0.4 0.57 10.1 0.1 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Syntaxin PF00804.25 RJW73647.1 - 0.085 12.5 1.1 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Syntaxin zf-C2H2_4 PF13894.6 RJW73647.1 - 0.48 11.4 0.1 0.48 11.4 0.1 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-RING_UBOX PF13445.6 RJW73647.1 - 1.6 8.8 7.1 0.45 10.6 0.6 3.1 3 0 0 3 3 3 0 RING-type zinc-finger ATP-synt_D PF01813.17 RJW73647.1 - 1.9 8.2 7.2 1.4 8.7 0.1 3.2 2 2 1 4 4 4 0 ATP synthase subunit D zf-C4 PF00105.18 RJW73650.1 - 3.1e-36 123.6 29.2 5.9e-25 87.5 14.9 2.6 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RJW73650.1 - 3.1e-08 33.5 0.1 6.9e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor HABP4_PAI-RBP1 PF04774.15 RJW73652.1 - 1.7e-05 25.7 5.3 1.7e-05 25.7 5.3 3.5 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family Suc_Fer-like PF06999.12 RJW73653.1 - 0.02 14.8 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Ion_trans_2 PF07885.16 RJW73654.1 - 7.9e-31 105.9 28.4 3.1e-16 59.1 10.2 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RJW73654.1 - 5.2e-06 25.9 7.5 0.0057 15.9 0.1 2.3 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.20 RJW73654.1 - 0.22 11.3 2.1 2.9 7.7 0.2 2.6 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF2633 PF11119.8 RJW73654.1 - 1.3 8.9 6.7 4.1 7.4 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) Ank_2 PF12796.7 RJW73655.1 - 1e-24 86.9 0.1 1.5e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RJW73655.1 - 1.2e-20 72.9 0.1 2.3e-07 30.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RJW73655.1 - 2.1e-20 72.5 0.5 4.8e-09 36.3 0.0 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW73655.1 - 1.6e-18 64.9 0.1 0.00015 22.0 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RJW73655.1 - 7.5e-18 64.7 0.3 7.1e-08 32.9 0.1 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) RVT_1 PF00078.27 RJW73657.1 - 0.00063 19.3 0.0 0.0012 18.3 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2252 PF10009.9 RJW73657.1 - 0.095 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Glyco_transf_64 PF09258.10 RJW73658.1 - 2.6e-88 295.5 0.2 4.1e-88 294.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 RJW73658.1 - 9.3e-12 44.8 0.0 2.1e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Exostosin family Glycos_transf_2 PF00535.26 RJW73658.1 - 0.22 11.3 0.9 1.2 8.9 0.9 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 2 Secretogranin_V PF05281.11 RJW73659.1 - 3.4e-21 75.9 4.9 3e-20 72.8 4.9 2.0 1 1 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) LIM PF00412.22 RJW73660.1 - 5.9e-54 180.1 43.7 5.6e-16 58.5 2.4 4.3 4 0 0 4 4 4 4 LIM domain zf-C4 PF00105.18 RJW73661.1 - 2.7e-05 24.5 3.0 5.7e-05 23.5 1.9 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 RJW73661.1 - 0.0087 16.4 3.7 0.018 15.4 3.7 1.5 1 0 0 1 1 1 1 C1 domain NDUF_B7 PF05676.13 RJW73662.1 - 6.3e-21 73.9 4.3 8.4e-21 73.5 4.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 RJW73662.1 - 0.0021 18.0 5.0 0.0026 17.7 5.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Piwi PF02171.17 RJW73663.1 - 1.1e-82 277.7 0.0 1.6e-82 277.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RJW73663.1 - 2.4e-11 43.6 0.0 4.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 RJW73663.1 - 3.8e-06 27.2 0.0 1.3e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 RJW73663.1 - 3.5e-05 23.4 0.0 9e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain zf_C2H2_ZHX PF18387.1 RJW73664.1 - 0.016 14.8 0.1 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Pro-rich_19 PF15455.6 RJW73664.1 - 0.088 11.9 0.0 0.1 11.7 0.0 1.0 1 0 0 1 1 1 0 Proline-rich 19 Serinc PF03348.15 RJW73666.1 - 0.14 11.0 6.7 0.23 10.4 6.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Comm PF15957.5 RJW73666.1 - 2 8.8 8.0 18 5.7 8.0 2.3 1 1 0 1 1 1 0 Commissureless RVT_1 PF00078.27 RJW73667.1 - 1.8e-10 40.7 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tn7_TnsC_Int PF11426.8 RJW73667.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC ENTH PF01417.20 RJW73668.1 - 2.2e-41 140.8 0.0 4.3e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 RJW73668.1 - 0.0056 15.7 0.0 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 ANTH domain PolC_DP2 PF03833.13 RJW73669.1 - 0.39 8.5 3.8 0.77 7.5 3.7 1.5 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 CEBP_ZZ PF16366.5 RJW73669.1 - 1.3 9.3 12.2 0.7 10.2 9.3 2.1 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 RJW73669.1 - 1.4 9.2 13.1 0.28 11.4 9.5 1.7 2 0 0 2 2 2 0 B-box zinc finger PspB PF06667.12 RJW73669.1 - 4.6 7.4 5.9 5 7.3 3.5 2.2 2 0 0 2 2 2 0 Phage shock protein B Homeodomain PF00046.29 RJW73670.1 - 3.3e-14 52.5 12.7 1.3e-11 44.1 0.0 3.0 3 0 0 3 3 3 2 Homeodomain MULE PF10551.9 RJW73671.1 - 1.1e-07 32.1 0.0 5.1e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain FlhC PF05280.11 RJW73671.1 - 0.021 14.6 0.9 0.039 13.7 0.9 1.4 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) HhH-GPD PF00730.25 RJW73672.1 - 5.1e-24 84.8 0.0 1.2e-23 83.6 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RJW73672.1 - 4e-09 35.9 0.1 1.8e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 RJW73672.1 - 0.19 12.4 0.0 0.89 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain WD40 PF00400.32 RJW73673.1 - 5e-51 169.6 22.9 7.3e-11 42.5 0.0 8.6 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73673.1 - 3.4e-26 91.4 4.0 1.8e-07 31.4 0.1 6.9 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW73673.1 - 2.2e-11 44.0 0.1 1.3e-05 25.2 0.0 3.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RJW73673.1 - 0.00031 19.8 0.2 0.42 9.5 0.0 3.4 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RJW73673.1 - 0.0014 17.4 1.9 0.72 8.4 0.0 4.6 4 2 2 6 6 6 1 Nucleoporin Nup120/160 IKI3 PF04762.12 RJW73673.1 - 0.003 15.6 0.3 0.071 11.1 0.0 2.3 3 0 0 3 3 3 1 IKI3 family Nucleoporin_N PF08801.11 RJW73673.1 - 0.0073 15.1 0.0 0.11 11.2 0.0 2.5 2 1 1 3 3 3 1 Nup133 N terminal like Reg_prop PF07494.11 RJW73673.1 - 0.021 15.0 0.1 3.4 8.2 0.0 3.6 4 0 0 4 4 2 0 Two component regulator propeller WD40_like PF17005.5 RJW73673.1 - 0.028 13.7 0.0 13 5.0 0.0 3.2 4 1 0 4 4 4 0 WD40-like domain PD40 PF07676.12 RJW73673.1 - 0.041 13.8 0.0 3.6 7.6 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 RJW73673.1 - 0.087 12.5 0.1 1.5 8.6 0.0 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature MULE PF10551.9 RJW73676.1 - 7e-18 64.8 0.1 1.2e-17 64.0 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain INTS5_C PF14838.6 RJW73677.1 - 0.00013 20.8 3.2 0.00055 18.7 3.3 1.8 1 1 0 1 1 1 1 Integrator complex subunit 5 C-terminus INTS5_N PF14837.6 RJW73677.1 - 0.00036 20.2 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus Y_phosphatase PF00102.27 RJW73685.1 - 6.8e-65 218.9 0.1 9.7e-65 218.4 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RJW73685.1 - 0.00022 21.1 0.0 0.00052 19.8 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RJW73685.1 - 0.0025 17.8 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 RJW73685.1 - 0.0031 17.2 0.0 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 RJW73685.1 - 0.029 14.5 0.0 0.089 12.9 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF3808 PF10300.9 RJW73686.1 - 1.3e-05 24.1 0.1 1.6e-05 23.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) eIF3g PF12353.8 RJW73687.1 - 0.018 15.4 2.1 0.024 15.0 2.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G PDZ PF00595.24 RJW73688.1 - 1.1e-55 185.9 0.0 1.7e-11 44.3 0.0 7.3 7 1 1 8 8 8 6 PDZ domain PDZ_6 PF17820.1 RJW73688.1 - 1e-40 137.4 7.6 5.3e-09 35.8 0.1 6.6 6 0 0 6 6 6 6 PDZ domain PDZ_2 PF13180.6 RJW73688.1 - 7e-22 77.6 0.0 0.0056 17.0 0.0 6.8 6 1 0 6 6 6 5 PDZ domain DTW PF03942.15 RJW73689.1 - 4.9e-37 127.6 0.1 5.6e-37 127.4 0.1 1.0 1 0 0 1 1 1 1 DTW domain Radical_SAM PF04055.21 RJW73690.1 - 5e-16 59.5 1.4 5.9e-16 59.3 0.3 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Phosducin PF02114.16 RJW73691.1 - 3.4e-12 45.9 0.0 4.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Phosducin SERTA PF06031.13 RJW73691.1 - 1.1 9.0 8.3 6.8 6.5 3.8 3.0 2 1 1 3 3 3 0 SERTA motif Trypsin PF00089.26 RJW73693.1 - 7.7e-49 166.5 0.0 1.6e-48 165.5 0.0 1.5 1 1 0 1 1 1 1 Trypsin RVT_1 PF00078.27 RJW73696.1 - 3.9e-35 121.4 0.0 8.4e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 RJW73696.1 - 2.1e-05 24.7 46.4 0.13 12.8 3.2 6.9 6 0 0 6 6 6 4 Zinc finger, C2H2 type PMG PF05287.12 RJW73696.1 - 0.016 15.2 19.8 0.49 10.4 5.8 2.6 2 0 0 2 2 2 0 PMG protein Myb_DNA-binding PF00249.31 RJW73696.1 - 0.085 13.1 0.0 1.5 9.0 0.0 3.1 4 0 0 4 4 4 0 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 RJW73696.1 - 0.31 12.0 47.1 0.37 11.8 1.3 7.0 6 0 0 6 6 6 0 C2H2-type zinc finger zinc_ribbon_6 PF14599.6 RJW73696.1 - 0.84 9.7 13.2 16 5.6 0.0 6.4 7 0 0 7 7 7 0 Zinc-ribbon zf-3CxxC PF13695.6 RJW73696.1 - 2.2 8.8 16.7 14 6.2 1.0 3.7 3 0 0 3 3 3 0 Zinc-binding domain MRAP PF15183.6 RJW73697.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family E1_DerP2_DerF2 PF02221.15 RJW73702.1 - 0.0024 18.3 0.0 0.0028 18.1 0.0 1.0 1 0 0 1 1 1 1 ML domain ANTH PF07651.16 RJW73704.1 - 2.8e-11 42.9 0.1 4.3e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 ANTH domain SWIRM-assoc_2 PF16496.5 RJW73705.1 - 1.7e-95 320.3 0.0 1.7e-95 320.3 0.0 2.7 3 0 0 3 3 3 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 RJW73705.1 - 4.6e-32 110.2 0.0 1.3e-31 108.8 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 RJW73705.1 - 7e-26 90.0 14.7 7e-26 90.0 14.7 2.4 1 1 1 2 2 2 1 SWIRM-associated region 1 SWIRM-assoc_3 PF16498.5 RJW73705.1 - 2.3e-21 75.8 2.0 2.3e-21 75.8 2.0 2.9 3 0 0 3 3 3 1 SWIRM-associated domain at the C-terminal Myb_DNA-binding PF00249.31 RJW73705.1 - 1.4e-12 47.6 0.4 3.4e-12 46.3 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RJW73705.1 - 2.2e-07 31.0 0.2 9.5e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Exonuc_VII_L PF02601.15 RJW73705.1 - 9.4 5.7 13.1 18 4.7 13.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DIL PF01843.19 RJW73707.1 - 2.7e-21 75.8 3.1 7.5e-21 74.4 3.1 1.8 1 0 0 1 1 1 1 DIL domain RA PF00788.23 RJW73707.1 - 8.8e-13 48.7 0.1 2.5e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 RJW73707.1 - 6e-12 45.7 0.0 1.6e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RJW73707.1 - 0.00069 19.4 0.4 0.0022 17.8 0.4 1.9 1 0 0 1 1 1 1 PDZ domain ORF6C PF10552.9 RJW73707.1 - 0.17 11.9 0.7 0.64 10.1 0.5 2.0 2 0 0 2 2 2 0 ORF6C domain MMR_HSR1 PF01926.23 RJW73710.1 - 1.7e-15 57.1 0.0 2.8e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 RJW73710.1 - 4.1e-15 55.7 0.5 1.7e-14 53.7 0.5 1.9 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 RJW73710.1 - 1.7e-09 37.4 0.0 3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 RJW73710.1 - 0.051 13.0 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.21 RJW73710.1 - 0.15 11.5 0.0 4.2 6.8 0.0 2.5 2 1 0 2 2 2 0 ADP-ribosylation factor family UBX PF00789.20 RJW73711.1 - 3.9e-06 27.0 0.0 9.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 UBX domain TUG-UBL1 PF11470.8 RJW73711.1 - 1.6e-05 25.0 0.0 4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain Evr1_Alr PF04777.13 RJW73713.1 - 5.3e-26 91.0 0.5 8.3e-26 90.4 0.1 1.5 2 0 0 2 2 2 1 Erv1 / Alr family Biopterin_H PF00351.21 RJW73716.1 - 8.9e-172 570.6 0.0 1.1e-171 570.4 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 RJW73716.1 - 1.6e-06 27.8 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain GIT_CC PF16559.5 RJW73716.1 - 0.2 11.6 1.6 0.39 10.6 1.6 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Radical_SAM_C PF16199.5 RJW73718.1 - 1e-15 57.5 0.1 1.7e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Acetyltransf_1 PF00583.25 RJW73718.1 - 9.6e-10 38.7 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RJW73718.1 - 3.1e-06 27.2 0.0 1.5e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RJW73718.1 - 0.0052 17.2 0.0 0.0092 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RJW73718.1 - 0.046 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein fn3 PF00041.21 RJW73719.1 - 3.4e-26 91.4 32.4 3.5e-06 27.3 0.4 11.1 11 0 0 11 11 11 6 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW73719.1 - 0.0025 18.3 24.8 0.15 12.6 0.2 7.8 7 1 0 7 7 7 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RJW73719.1 - 0.0059 16.9 2.2 2.2 8.6 0.0 4.2 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III Vault_3 PF17795.1 RJW73719.1 - 0.1 12.6 0.2 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Major Vault Protein Repeat domain Syja_N PF02383.18 RJW73723.1 - 7.3e-80 268.7 0.0 1e-79 268.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain RVT_1 PF00078.27 RJW73723.1 - 1.8e-39 135.6 0.0 3.1e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 RJW73724.1 - 4.5e-36 122.5 0.1 3e-18 65.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW73724.1 - 3.1e-13 49.6 0.0 6.4e-07 29.4 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RJW73724.1 - 1.4e-06 28.2 0.1 8.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 RJW73724.1 - 0.00052 20.0 0.1 0.051 13.6 0.1 2.3 2 0 0 2 2 2 1 RNA binding motif RL PF17797.1 RJW73724.1 - 0.03 14.3 0.0 6.4 6.8 0.0 2.5 2 0 0 2 2 2 0 RL domain Peptidase_M16_C PF05193.21 RJW73724.1 - 0.035 14.1 0.0 1.1 9.2 0.0 2.3 1 1 1 2 2 2 0 Peptidase M16 inactive domain DUF4651 PF15513.6 RJW73724.1 - 0.059 13.2 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) OB_RNB PF08206.11 RJW73724.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 RJW73724.1 - 0.15 12.3 0.6 3.9 7.7 0.4 3.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF3808 PF10300.9 RJW73725.1 - 2.4e-89 300.3 6.3 5.1e-89 299.2 6.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 RJW73725.1 - 5.4e-06 26.6 3.8 0.0042 17.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RJW73725.1 - 0.00021 21.8 0.4 1.9 9.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RJW73725.1 - 0.0023 17.9 5.7 2 8.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RJW73725.1 - 0.0065 17.0 5.6 5 7.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RJW73725.1 - 0.028 14.6 0.0 0.28 11.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 RJW73725.1 - 0.23 12.2 1.7 15 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 RJW73725.1 - 0.4 10.6 5.3 11 6.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RJW73725.1 - 0.91 10.5 5.8 7.2 7.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SBF2 PF12335.8 RJW73726.1 - 9.5e-07 28.7 3.7 9.5e-07 28.7 3.7 1.5 1 1 0 1 1 1 1 Myotubularin protein DUF5566 PF17721.1 RJW73726.1 - 0.033 14.4 0.3 0.053 13.8 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5566) PI_PP_C PF18365.1 RJW73726.1 - 0.11 12.5 1.4 0.34 10.9 0.1 2.3 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain Y_phosphatase PF00102.27 RJW73727.1 - 7e-57 192.7 0.0 1.4e-56 191.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 RJW73727.1 - 4.5e-16 59.0 8.6 8e-09 35.7 1.1 4.8 4 1 0 4 4 4 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RJW73727.1 - 0.0043 17.6 4.2 0.0083 16.7 1.0 2.9 3 1 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain DSPc PF00782.20 RJW73727.1 - 0.03 14.1 0.0 0.098 12.5 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain DUF3751 PF12571.8 RJW73727.1 - 0.034 14.2 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 Phage tail-collar fibre protein Y_phosphatase3 PF13350.6 RJW73727.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family MitoNEET_N PF10660.9 RJW73727.1 - 0.069 13.2 0.0 0.33 11.0 0.0 2.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Cofilin_ADF PF00241.20 RJW73729.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein bMG3 PF11974.8 RJW73729.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain rve PF00665.26 RJW73731.1 - 1.8e-24 86.2 0.1 4.3e-24 85.0 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 RJW73731.1 - 3.6e-05 23.4 0.6 0.00039 20.1 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain NHase_beta PF02211.15 RJW73731.1 - 0.062 13.3 0.2 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Nitrile hydratase beta subunit Trypsin PF00089.26 RJW73734.1 - 1.8e-58 197.9 0.0 1.8e-57 194.7 0.0 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RJW73734.1 - 0.00024 22.0 0.0 0.00047 21.1 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Globin PF00042.22 RJW73736.1 - 2.4e-15 57.0 0.0 7.3e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 Globin RasGEF_N PF00618.20 RJW73739.1 - 6.3e-12 45.7 0.7 4.1e-09 36.6 0.7 2.7 1 1 0 1 1 1 1 RasGEF N-terminal motif cNMP_binding PF00027.29 RJW73739.1 - 1.9e-11 43.9 0.0 1.8e-07 31.1 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RasGEF PF00617.19 RJW73739.1 - 8.5e-07 29.3 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain PDZ_6 PF17820.1 RJW73739.1 - 0.0014 18.4 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain His_Phos_1 PF00300.22 RJW73740.1 - 6.4e-17 61.9 0.5 5.2e-09 36.1 0.1 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) CRAL_TRIO PF00650.20 RJW73743.1 - 7.3e-24 84.3 0.0 2.6e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RJW73743.1 - 7.4e-08 32.5 0.0 2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 RJW73743.1 - 4.2e-07 30.2 0.0 8.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RSB_motif PF16294.5 RJW73745.1 - 2e-18 66.6 5.6 2e-18 66.6 5.6 6.6 4 1 1 5 5 5 1 RNSP1-SAP18 binding (RSB) motif RRM_1 PF00076.22 RJW73745.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-1_beta_acid PF10587.9 RJW73745.1 - 0.15 12.5 5.9 0.32 11.5 5.9 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region RRM_occluded PF16842.5 RJW73745.1 - 0.18 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-H2C2_2 PF13465.6 RJW73746.1 - 1.3e-24 85.4 47.6 1.8e-05 25.0 2.5 7.5 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 RJW73746.1 - 7.2e-24 82.9 55.9 6.1e-06 26.4 0.6 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW73746.1 - 5.5e-15 54.8 51.5 0.005 17.6 1.4 6.7 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW73746.1 - 9.5e-07 28.7 44.4 0.012 15.6 0.1 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW73746.1 - 0.004 17.4 37.7 0.15 12.3 1.0 6.5 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RJW73746.1 - 0.02 14.7 0.0 0.02 14.7 0.0 4.4 5 0 0 5 5 4 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 RJW73746.1 - 0.061 13.5 18.4 0.3 11.3 0.6 4.7 2 2 2 4 4 4 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 RJW73746.1 - 0.095 12.6 11.8 6.3 6.7 1.2 3.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) CpXC PF14353.6 RJW73746.1 - 0.11 12.5 0.2 0.11 12.5 0.2 3.9 1 1 3 4 4 4 0 CpXC protein zf_UBZ PF18439.1 RJW73746.1 - 0.14 11.7 0.1 0.14 11.7 0.1 5.5 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger PknG_rubred PF16919.5 RJW73746.1 - 0.15 12.2 4.1 0.68 10.1 0.9 2.9 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain OrfB_Zn_ribbon PF07282.11 RJW73746.1 - 0.34 10.9 0.1 0.34 10.9 0.1 4.4 3 1 1 4 4 4 0 Putative transposase DNA-binding domain zf-met PF12874.7 RJW73746.1 - 0.43 11.0 32.1 3.1 8.3 0.4 6.5 5 1 0 6 6 6 0 Zinc-finger of C2H2 type ADK_lid PF05191.14 RJW73746.1 - 1.7 8.7 20.1 9.7 6.3 3.9 4.4 2 2 2 4 4 4 0 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 RJW73746.1 - 2 8.5 17.9 2.4 8.3 1.7 5.5 4 2 1 5 5 5 0 Sec23/Sec24 zinc finger BolA PF01722.18 RJW73746.1 - 4.1 7.8 7.0 40 4.6 0.1 3.1 2 1 0 2 2 2 0 BolA-like protein GAGA PF09237.11 RJW73746.1 - 5.2 7.0 16.5 17 5.3 0.1 5.3 1 1 5 6 6 6 0 GAGA factor zinc_ribbon_15 PF17032.5 RJW73746.1 - 5.3 7.9 19.7 5.8 7.7 2.4 3.8 1 1 4 5 5 5 0 zinc-ribbon family zf-ribbon_3 PF13248.6 RJW73746.1 - 5.8 6.5 7.6 2.9 7.4 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain FYVE PF01363.21 RJW73746.1 - 7.2 6.8 29.7 1.2 9.4 6.7 4.0 1 1 2 3 3 3 0 FYVE zinc finger GNAT_acetyltr_2 PF13718.6 RJW73747.1 - 6.4e-92 307.1 0.0 3.5e-64 216.3 0.0 2.6 1 1 1 2 2 2 2 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 RJW73747.1 - 1.1e-51 175.2 0.0 2.4e-51 174.1 0.0 1.6 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 RJW73747.1 - 3.3e-36 125.2 0.1 3.3e-36 125.2 0.1 3.2 3 0 0 3 3 3 2 Possible tRNA binding domain DUF1726 PF08351.11 RJW73747.1 - 8.3e-33 112.2 0.0 2.2e-32 110.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_7 PF13508.7 RJW73747.1 - 0.018 15.5 0.0 0.065 13.7 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RJW73747.1 - 0.084 13.1 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AAA_22 PF13401.6 RJW73747.1 - 0.1 12.9 0.0 2.4 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain VWA PF00092.28 RJW73748.1 - 1.1e-11 45.2 0.0 3.9e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RJW73748.1 - 0.026 15.1 0.0 0.068 13.8 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain TMV_coat PF00721.21 RJW73748.1 - 0.12 12.2 2.2 0.15 11.9 0.3 2.1 2 0 0 2 2 2 0 Virus coat protein (TMV like) DUF572 PF04502.13 RJW73750.1 - 1.4e-71 241.9 2.3 1.9e-71 241.4 2.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) SET PF00856.28 RJW73750.1 - 3.2e-07 30.9 0.0 2.7e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 SET domain Mut7-C PF01927.16 RJW73750.1 - 0.052 13.6 0.3 0.052 13.6 0.3 2.3 3 0 0 3 3 3 0 Mut7-C RNAse domain Atg8 PF02991.16 RJW73751.1 - 1.3e-34 118.5 0.0 1.4e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RJW73751.1 - 1.8e-07 31.5 0.0 2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 BUD22 PF09073.10 RJW73752.1 - 0.022 14.1 15.1 0.026 13.9 15.1 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 RJW73752.1 - 0.14 12.0 9.7 0.17 11.7 9.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 RJW73752.1 - 0.21 11.0 15.6 0.27 10.6 15.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RJW73752.1 - 0.31 9.2 18.0 0.33 9.1 18.0 1.1 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 RJW73752.1 - 0.67 9.8 8.2 0.79 9.5 8.2 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term eIF-3c_N PF05470.12 RJW73752.1 - 0.85 7.8 6.6 1.1 7.5 6.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 RJW73752.1 - 0.99 7.6 14.8 1.1 7.5 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RJW73752.1 - 1.3 7.0 27.5 1.8 6.6 27.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 RJW73752.1 - 5.1 5.8 7.2 5.6 5.6 7.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.16 RJW73752.1 - 8.3 5.5 11.5 15 4.6 11.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cwf_Cwc_15 PF04889.12 RJW73752.1 - 8.9 6.0 26.3 2.1 8.0 23.0 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DBR1 PF05011.13 RJW73754.1 - 6e-31 107.7 0.3 1.8e-30 106.2 0.3 1.9 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 RJW73754.1 - 9.7e-08 32.7 0.1 1.5e-07 32.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RJW73754.1 - 0.019 15.1 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Sigma70_ner PF04546.13 RJW73754.1 - 0.56 10.1 4.5 1.2 9.0 4.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 RJW73754.1 - 1.7 6.6 8.5 2.6 6.1 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Foie-gras_1 PF11817.8 RJW73756.1 - 7.1e-48 163.5 3.2 2.8e-45 154.9 3.2 2.2 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 RJW73756.1 - 9.2e-12 44.8 0.2 1.8e-11 43.8 0.2 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Gryzun PF07919.12 RJW73756.1 - 4.6e-10 38.9 0.4 1.7e-09 37.0 0.1 1.9 2 0 0 2 2 2 1 Gryzun, putative trafficking through Golgi TPR_1 PF00515.28 RJW73756.1 - 0.022 14.6 3.9 0.043 13.7 0.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RJW73756.1 - 0.11 12.7 5.1 0.14 12.3 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2393 PF09624.10 RJW73756.1 - 0.11 12.5 0.0 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) TPR_11 PF13414.6 RJW73756.1 - 5.7 6.7 5.2 1.6 8.4 0.4 2.3 2 0 0 2 2 2 0 TPR repeat CRAL_TRIO PF00650.20 RJW73757.1 - 1.7e-06 27.9 0.0 2.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RJW73757.1 - 5.5e-06 26.5 0.3 8.6e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 RJW73758.1 - 3.5e-13 49.6 0.0 6.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Retrotran_gag_2 PF14223.6 RJW73758.1 - 0.062 13.0 0.2 0.29 10.8 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type TTRAP PF14203.6 RJW73758.1 - 0.079 13.0 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein PX PF00787.24 RJW73759.1 - 5.2e-14 52.2 3.6 8.8e-14 51.5 2.3 2.2 2 0 0 2 2 2 1 PX domain PXA PF02194.15 RJW73759.1 - 8.2e-13 48.7 0.4 2e-06 27.9 0.0 3.2 3 0 0 3 3 3 2 PXA domain SAPS PF04499.15 RJW73760.1 - 5.3e-36 124.5 0.0 6e-23 81.4 0.0 3.8 3 2 1 4 4 4 2 SIT4 phosphatase-associated protein Nop14 PF04147.12 RJW73760.1 - 4.4 5.4 5.0 6.9 4.7 5.0 1.2 1 0 0 1 1 1 0 Nop14-like family DIE2_ALG10 PF04922.12 RJW73762.1 - 1.6e-102 343.8 35.5 2.1e-102 343.4 35.5 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Mannosyl_trans4 PF15971.5 RJW73762.1 - 0.00033 20.5 0.6 0.0015 18.4 0.6 2.1 1 0 0 1 1 1 1 DolP-mannose mannosyltransferase DUF5134 PF17197.4 RJW73762.1 - 8.4 6.3 9.2 1.9e+02 1.9 5.9 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) WD40 PF00400.32 RJW73763.1 - 2.1e-33 113.8 7.7 2.3e-06 28.2 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73763.1 - 1.3e-08 35.0 0.1 0.19 12.1 0.0 4.8 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Me-amine-dh_H PF06433.11 RJW73763.1 - 0.0055 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.6 RJW73763.1 - 0.0083 15.7 0.0 0.021 14.4 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 RJW73763.1 - 0.0086 15.4 0.0 2.7 7.2 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 RJW73763.1 - 0.045 12.4 0.0 0.087 11.4 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 VHS PF00790.19 RJW73766.1 - 1.4e-20 73.6 0.3 5.7e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain GGA_N-GAT PF18308.1 RJW73766.1 - 7.3e-17 60.7 1.5 1.4e-16 59.8 1.5 1.5 1 0 0 1 1 1 1 GGA N-GAT domain Alpha_adaptinC2 PF02883.20 RJW73766.1 - 4.5e-09 36.6 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 RJW73766.1 - 2.5e-07 30.9 0.8 2.5e-07 30.9 0.8 2.3 2 0 0 2 2 2 1 GAT domain Csm1_N PF18504.1 RJW73766.1 - 0.0016 18.8 2.6 0.0032 17.8 2.6 1.5 1 0 0 1 1 1 1 Csm1 N-terminal domain MutS_III PF05192.18 RJW73766.1 - 1 9.6 4.0 2.2 8.4 4.0 1.7 1 1 0 1 1 1 0 MutS domain III TNFR_16_TM PF18422.1 RJW73767.1 - 0.044 13.7 1.9 0.074 13.0 1.9 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Surp PF01805.20 RJW73768.1 - 4.5e-17 61.8 0.6 1e-16 60.7 0.6 1.7 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 RJW73768.1 - 7e-17 62.0 0.7 1.4e-16 61.1 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. SHE3 PF17078.5 RJW73768.1 - 0.18 11.5 4.0 0.069 12.9 0.7 1.9 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 HLH PF00010.26 RJW73769.1 - 2.7e-12 46.5 1.0 6e-12 45.3 0.7 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RVT_1 PF00078.27 RJW73770.1 - 1.5e-07 31.2 0.0 2.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArgoMid PF16487.5 RJW73770.1 - 0.15 12.4 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 Mid domain of argonaute SAGA-Tad1 PF12767.7 RJW73771.1 - 0.064 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ham1p_like PF01725.16 RJW73772.1 - 4.2e-53 180.1 0.0 4.7e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Spond_N PF06468.13 RJW73773.1 - 1.3e-44 152.7 0.0 2.1e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Spondin_N Kunitz_BPTI PF00014.23 RJW73773.1 - 1.9e-26 92.1 16.7 8.9e-14 51.5 3.4 3.0 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain TSP_1 PF00090.19 RJW73773.1 - 1.3e-14 54.1 31.0 2.4e-08 34.0 5.7 4.7 4 0 0 4 4 4 3 Thrombospondin type 1 domain YqhG PF11079.8 RJW73775.1 - 0.099 11.6 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Edc3_linker PF16598.5 RJW73775.1 - 0.11 13.1 0.2 0.14 12.8 0.2 1.2 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 IRS PF02174.17 RJW73776.1 - 6.8e-06 25.9 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Radial_spoke_3 PF06098.11 RJW73778.1 - 2.1e-112 375.1 8.6 2.1e-112 375.1 8.6 1.9 1 1 1 2 2 2 1 Radial spoke protein 3 LprI PF07007.12 RJW73778.1 - 10 6.9 9.8 1.4 9.6 3.9 2.5 2 1 1 3 3 3 0 Lysozyme inhibitor LprI Ribosomal_L3 PF00297.22 RJW73779.1 - 9.6e-17 61.0 3.3 4.6e-15 55.5 3.2 2.7 2 1 1 3 3 3 2 Ribosomal protein L3 MFS_1 PF07690.16 RJW73780.1 - 4.1e-10 39.1 6.4 5.8e-10 38.6 6.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 RJW73782.1 - 2.3e-27 95.9 28.6 2.2e-18 66.3 1.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily cNMP_binding PF00027.29 RJW73785.1 - 4.3e-30 103.6 0.0 1.4e-19 70.0 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 RJW73785.1 - 1.8e-08 33.9 0.0 4.8e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit PFU PF09070.11 RJW73785.1 - 0.025 14.9 0.3 0.066 13.5 0.1 1.8 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) Dpy-30 PF05186.13 RJW73785.1 - 0.084 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Dpy-30 motif DM PF00751.18 RJW73786.1 - 9.2e-22 76.7 9.3 1.7e-21 75.8 9.3 1.5 1 0 0 1 1 1 1 DM DNA binding domain GDC-P PF02347.16 RJW73787.1 - 4.8e-07 29.0 0.1 8.3e-05 21.6 0.0 3.4 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 RJW73787.1 - 0.00091 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase AAA PF00004.29 RJW73788.1 - 9.2e-13 48.8 0.0 2.1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RJW73788.1 - 1.5e-12 48.2 0.8 1.9e-11 44.6 0.3 2.7 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 RJW73788.1 - 3.2e-12 46.2 0.2 1.6e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 RJW73788.1 - 4.5e-11 43.2 0.0 1.4e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 RJW73788.1 - 4.4e-09 36.4 0.5 9.5e-09 35.3 0.5 1.5 1 0 0 1 1 1 1 AAA lid domain DUF2075 PF09848.9 RJW73788.1 - 0.00013 21.3 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 RJW73788.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 RJW73788.1 - 0.0061 16.0 0.0 0.022 14.2 0.0 1.9 1 1 0 1 1 1 1 Bacterial TniB protein AAA_19 PF13245.6 RJW73788.1 - 0.011 16.1 0.1 0.029 14.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 RJW73788.1 - 0.055 13.8 0.1 0.2 12.0 0.1 1.9 1 0 0 1 1 1 0 AAA C-terminal domain SR-25 PF10500.9 RJW73788.1 - 0.094 12.3 18.9 0.16 11.5 18.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dynein_light PF01221.18 RJW73789.1 - 2.4e-09 37.4 0.1 4.5e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Dynein light chain type 1 CreD PF06123.12 RJW73789.1 - 0.058 12.2 0.4 0.073 11.8 0.4 1.1 1 0 0 1 1 1 0 Inner membrane protein CreD DUF1970 PF09301.10 RJW73790.1 - 0.13 12.5 2.2 0.18 12.1 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) ERCC4 PF02732.15 RJW73791.1 - 2.1e-19 70.3 0.0 1.1e-18 67.9 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.6 RJW73791.1 - 0.075 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_2 PF12826.7 RJW73791.1 - 0.084 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ge1_WD40 PF16529.5 RJW73792.1 - 3.3e-44 151.2 0.0 2.5e-43 148.3 0.0 2.3 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 RJW73792.1 - 0.00058 20.6 1.2 0.054 14.4 0.1 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat TAF4 PF05236.14 RJW73793.1 - 1.7e-24 87.0 0.0 2.6e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.14 RJW73793.1 - 1.1e-10 41.4 0.0 3.5e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 NHR1 homology to TAF RVT_1 PF00078.27 RJW73794.1 - 1.2e-07 31.5 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 RJW73794.1 - 0.0011 19.2 0.1 0.0022 18.2 0.1 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain OHA PF14418.6 RJW73795.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 OST-HTH Associated domain RVT_1 PF00078.27 RJW73796.1 - 5.8e-11 42.3 0.2 5.8e-05 22.7 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Phosphodiest PF01663.22 RJW73797.1 - 1.3e-65 222.4 0.4 1.6e-65 222.0 0.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RJW73797.1 - 1.3e-07 31.3 0.0 0.0098 15.3 0.0 2.5 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 RJW73797.1 - 0.00026 20.4 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 RJW73797.1 - 0.13 12.3 0.0 0.72 9.9 0.0 2.0 2 0 0 2 2 2 0 PglZ domain DUF1281 PF06924.11 RJW73798.1 - 0.094 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) Rota_NS6 PF04866.12 RJW73799.1 - 0.063 13.5 0.1 0.12 12.6 0.1 1.4 1 1 0 1 1 1 0 Rotavirus non-structural protein 6 gpW PF02831.15 RJW73800.1 - 0.02 14.8 0.2 0.7 9.8 0.0 3.1 2 0 0 2 2 2 0 gpW P-mevalo_kinase PF04275.14 RJW73800.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.3 3 0 0 3 3 3 0 Phosphomevalonate kinase LMP PF04778.12 RJW73800.1 - 0.3 11.0 0.1 0.3 11.0 0.1 4.0 3 1 1 4 4 4 0 LMP repeated region PET PF06297.14 RJW73800.1 - 2 8.8 8.2 0.81 10.0 1.4 3.3 3 0 0 3 3 3 0 PET Domain APCDDC PF14921.6 RJW73800.1 - 5.8 6.3 13.0 0.55 9.6 2.9 2.8 2 0 0 2 2 2 0 Adenomatosis polyposis coli down-regulated 1 YhdB PF14148.6 RJW73801.1 - 0.13 12.4 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 YhdB-like protein zf-CCHC PF00098.23 RJW73804.1 - 7.8e-06 25.7 3.2 7.8e-06 25.7 3.2 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-RING_UBOX PF13445.6 RJW73804.1 - 0.0048 16.9 5.9 0.0048 16.9 5.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 RJW73804.1 - 0.005 17.1 5.0 0.005 17.1 5.0 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 RJW73804.1 - 0.0062 16.4 5.3 0.0062 16.4 5.3 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RJW73804.1 - 0.0083 16.0 4.7 0.0083 16.0 4.7 2.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-CCHC_4 PF14392.6 RJW73804.1 - 0.09 12.5 2.7 0.32 10.8 2.7 2.0 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 RJW73811.1 - 3.1e-67 226.7 0.0 4e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW73811.1 - 7.6e-37 127.0 0.0 1e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 RJW73811.1 - 8e-10 38.7 0.0 1.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 RJW73811.1 - 2.5e-08 33.6 0.0 9.2e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RJW73811.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RJW73811.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 RJW73811.1 - 0.15 12.8 0.1 1.2 9.9 0.0 2.6 2 0 0 2 2 2 0 Protein kinase C terminal domain TFIID-18kDa PF02269.16 RJW73812.1 - 6.5e-27 93.4 0.1 8.7e-27 93.0 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 RJW73814.1 - 2.1e-19 69.6 1.0 4.1e-19 68.6 1.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RJW73814.1 - 2.8e-13 50.4 1.7 7.5e-13 49.0 1.7 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 RJW73814.1 - 0.0062 16.8 0.2 0.018 15.4 0.2 1.8 1 0 0 1 1 1 1 CENP-S associating Centromere protein X YuzL PF14115.6 RJW73814.1 - 0.1 13.1 5.4 1.2 9.7 0.4 2.8 2 0 0 2 2 2 0 YuzL-like protein Dynein_light PF01221.18 RJW73815.1 - 4.9e-09 36.4 0.6 1.4e-08 34.9 0.6 1.8 1 0 0 1 1 1 1 Dynein light chain type 1 Cupredoxin_1 PF13473.6 RJW73817.1 - 0.0059 16.7 0.6 0.21 11.7 0.0 3.6 5 0 0 5 5 5 1 Cupredoxin-like domain zf-C2H2_4 PF13894.6 RJW73819.1 - 1.7e-20 71.9 72.9 0.00084 20.0 0.1 10.1 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.26 RJW73819.1 - 5e-16 58.2 71.4 0.00051 20.3 0.2 9.5 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RJW73819.1 - 5.6e-13 48.7 51.2 0.037 14.5 0.2 10.1 10 1 0 10 10 10 6 Zinc-finger double domain zf-Di19 PF05605.12 RJW73819.1 - 9.9e-09 35.4 42.3 1.9e-05 24.8 3.2 5.9 3 2 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RJW73819.1 - 2.3e-07 30.6 54.5 0.00011 22.1 0.1 9.4 9 1 0 9 9 9 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 RJW73819.1 - 0.0006 19.7 43.0 0.41 10.6 1.1 8.0 8 0 0 8 8 7 5 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 RJW73819.1 - 0.024 14.7 26.2 0.84 9.8 1.5 6.2 5 1 1 6 6 6 0 Zinc ribbon domain zf-met PF12874.7 RJW73819.1 - 0.034 14.5 53.1 0.22 12.0 0.1 9.9 10 0 0 10 10 10 0 Zinc-finger of C2H2 type RAG1_imp_bd PF12560.8 RJW73819.1 - 0.41 10.1 20.2 2.2 7.7 0.2 4.9 5 1 1 6 6 6 0 RAG1 importin binding Elf1 PF05129.13 RJW73819.1 - 0.49 10.5 25.3 0.92 9.6 0.8 5.3 1 1 5 6 6 6 0 Transcription elongation factor Elf1 like zf-C2H2_3rep PF18868.1 RJW73819.1 - 1.1 10.0 29.1 0.043 14.5 9.8 4.9 3 1 1 4 4 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 RJW73819.1 - 1.2 9.5 0.0 1.2 9.5 0.0 8.0 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding HypA PF01155.19 RJW73819.1 - 7.9 6.5 21.0 15 5.6 2.9 5.0 1 1 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LIM PF00412.22 RJW73820.1 - 1.2e-06 28.6 3.6 2.8e-06 27.4 3.6 1.6 1 0 0 1 1 1 1 LIM domain Pyr_redox_2 PF07992.14 RJW73820.1 - 1.2e-05 24.7 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RJW73820.1 - 1.8e-05 24.2 1.1 2.4e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 RJW73820.1 - 8.1e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 RJW73820.1 - 9.8e-05 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RJW73820.1 - 9.8e-05 21.2 0.0 0.00019 20.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 RJW73820.1 - 0.0019 18.4 0.0 0.0052 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RJW73820.1 - 0.0021 17.7 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 RJW73820.1 - 0.0027 18.2 0.0 0.0071 16.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RJW73820.1 - 0.0029 16.7 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 RJW73820.1 - 0.0062 15.8 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family CH PF00307.31 RJW73820.1 - 0.037 14.2 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Calponin homology (CH) domain FAD_oxidored PF12831.7 RJW73820.1 - 0.038 13.4 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 RJW73820.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 RJW73820.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NDUF_B6 PF09782.9 RJW73821.1 - 8.9e-19 68.1 0.4 1.5e-18 67.4 0.4 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Imm12 PF15560.6 RJW73821.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 12 Phosphodiest PF01663.22 RJW73823.1 - 3.1e-59 201.4 1.0 3.9e-59 201.0 1.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RJW73823.1 - 2.7e-06 27.0 0.0 0.012 15.1 0.0 2.6 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 RJW73823.1 - 0.00014 21.4 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Corona_S2 PF01601.16 RJW73823.1 - 0.0043 15.6 0.1 0.0057 15.2 0.1 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein PglZ PF08665.12 RJW73823.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 PglZ domain SLAC1 PF03595.17 RJW73825.1 - 0.0016 17.8 0.0 0.0019 17.5 0.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SieB PF14163.6 RJW73825.1 - 0.028 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF1404 PF07185.11 RJW73825.1 - 0.032 14.0 0.3 0.04 13.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1404) LPG_synthase_TM PF03706.13 RJW73825.1 - 0.091 12.3 0.0 0.096 12.2 0.0 1.0 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region SNF2_N PF00176.23 RJW73827.1 - 1.9e-61 207.8 0.1 3.2e-61 207.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RJW73827.1 - 7.7e-19 68.1 0.0 2.2e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 RJW73827.1 - 1.5e-12 47.2 11.6 1.1e-07 31.6 0.3 4.0 3 1 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain BRK PF07533.16 RJW73827.1 - 1.6e-10 40.4 0.0 3.6e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 BRK domain ResIII PF04851.15 RJW73827.1 - 6.1e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Myb_DNA-bind_7 PF15963.5 RJW73827.1 - 0.031 14.2 0.0 0.098 12.6 0.0 1.8 1 0 0 1 1 1 0 Myb DNA-binding like HDA2-3 PF11496.8 RJW73827.1 - 0.11 11.6 0.2 0.88 8.7 0.2 2.2 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 E1-E2_ATPase PF00122.20 RJW73828.1 - 1.8e-50 171.0 3.0 1.9e-50 170.9 0.2 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RJW73828.1 - 9.3e-44 149.3 5.7 9.3e-44 149.3 5.7 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RJW73828.1 - 1.3e-16 61.5 0.1 1.7e-15 57.9 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RJW73828.1 - 2.6e-15 55.9 0.0 5.1e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 RJW73828.1 - 2.6e-13 49.9 0.0 6.6e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RJW73828.1 - 0.034 13.9 0.7 0.061 13.1 0.7 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SPC12 PF06645.13 RJW73828.1 - 0.58 10.3 2.2 1.1 9.4 0.2 2.5 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF4271 PF14093.6 RJW73828.1 - 5.6 6.8 11.1 11 5.8 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) Macscav_rec PF03523.13 RJW73832.1 - 2.4 8.1 6.3 4.6 7.2 3.0 2.8 2 0 0 2 2 2 0 Macrophage scavenger receptor Aldedh PF00171.22 RJW73833.1 - 1.4e-74 251.3 0.0 1.6e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 RJW73833.1 - 0.0018 17.4 0.0 0.0026 16.9 0.0 1.3 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RVT_1 PF00078.27 RJW73833.1 - 0.022 14.3 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 RJW73834.1 - 1.7e-15 57.1 22.7 5.5e-05 23.8 0.3 9.4 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73834.1 - 1.1e-06 28.9 0.3 0.38 11.1 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Tub PF01167.18 RJW73835.1 - 1.9e-59 201.3 0.0 4.4e-59 200.2 0.0 1.6 1 0 0 1 1 1 1 Tub family TFIIS_M PF07500.14 RJW73836.1 - 4.4e-32 110.9 1.8 8.3e-32 110.0 1.8 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 RJW73836.1 - 9.3e-18 63.8 7.0 1.9e-17 62.8 7.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 RJW73836.1 - 2.1e-11 43.7 1.8 2.1e-11 43.7 1.8 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Sad1_UNC PF07738.13 RJW73837.1 - 2e-31 108.7 0.0 4.3e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF16 PF01519.16 RJW73837.1 - 0.0075 16.7 0.1 0.0075 16.7 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 RJW73837.1 - 0.15 12.1 19.7 0.13 12.2 1.3 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fmp27_WPPW PF10359.9 RJW73837.1 - 1.7 7.4 18.5 0.41 9.4 2.1 2.4 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain BLOC1_2 PF10046.9 RJW73837.1 - 2.2 8.6 4.9 0.73 10.2 0.3 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkinase PF00069.25 RJW73838.1 - 5.4e-65 219.4 0.0 7.8e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW73838.1 - 6e-26 91.3 0.0 1e-25 90.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW73838.1 - 0.0043 16.0 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain VPS13_C PF16909.5 RJW73839.1 - 1.1e-07 31.8 0.0 0.0064 16.3 0.0 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Gelsolin PF00626.22 RJW73840.1 - 4.2e-09 36.2 0.4 2e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat LRRNT PF01462.18 RJW73841.1 - 0.024 14.3 0.0 0.066 12.9 0.0 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Rtf2 PF04641.12 RJW73842.1 - 5.3e-77 258.7 0.4 6e-77 258.5 0.4 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Herpes_DNAp_acc PF04929.12 RJW73842.1 - 0.013 14.5 3.2 0.015 14.3 3.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor zf-NOSIP PF15906.5 RJW73842.1 - 0.013 15.6 0.1 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein MRI PF15325.6 RJW73842.1 - 2.5 9.3 6.8 4.6 8.4 6.8 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection Pex14_N PF04695.13 RJW73842.1 - 8.9 6.9 14.4 18 6.0 14.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RhoGEF PF00621.20 RJW73843.1 - 1.5e-23 84.0 0.0 5.7e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.6 RJW73843.1 - 0.0011 19.2 0.0 0.0063 16.8 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain CRAL_TRIO PF00650.20 RJW73843.1 - 0.002 17.9 0.0 0.0048 16.6 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain PH PF00169.29 RJW73843.1 - 0.02 15.4 0.0 0.089 13.3 0.0 2.2 1 1 0 1 1 1 0 PH domain CRAL_TRIO_2 PF13716.6 RJW73843.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF4771 PF15995.5 RJW73843.1 - 0.14 12.4 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) RVT_1 PF00078.27 RJW73846.1 - 6.9e-10 38.8 0.0 2.3e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Na_trans_assoc PF06512.13 RJW73846.1 - 0.18 12.1 7.4 0.52 10.6 7.4 1.8 1 1 0 1 1 1 0 Sodium ion transport-associated NAD_binding_7 PF13241.6 RJW73846.1 - 0.24 11.9 0.8 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding RNA_pol_Rpc4 PF05132.14 RJW73848.1 - 0.033 14.6 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CAP PF00188.26 RJW73849.1 - 2e-11 44.8 4.3 2.1e-11 44.8 4.3 1.0 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 RJW73850.1 - 5.5e-27 95.1 3.5 6.6e-27 94.8 3.5 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Fucose_iso_N2 PF07882.12 RJW73850.1 - 0.07 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain EMC3_TMCO1 PF01956.16 RJW73854.1 - 1.9e-29 102.5 0.1 2.1e-29 102.4 0.1 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Holin_BhlA PF10960.8 RJW73854.1 - 0.21 11.5 1.0 5.6 7.0 0.9 2.2 2 0 0 2 2 2 0 BhlA holin family Collagen PF01391.18 RJW73855.1 - 3.9e-10 39.3 10.2 3.7e-09 36.2 10.2 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) RNase_H2_suC PF08615.11 RJW73857.1 - 0.11 12.7 1.1 0.58 10.3 1.0 2.2 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) WH1 PF00568.23 RJW73862.1 - 3.1e-25 88.3 0.0 4.8e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 RJW73862.1 - 1.3e-08 34.3 0.2 2.1e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 VASP tetramerisation domain Folliculin PF11704.8 RJW73862.1 - 0.026 14.4 1.2 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Ran_BP1 PF00638.18 RJW73862.1 - 0.074 13.3 0.0 0.27 11.5 0.0 1.8 1 1 0 1 1 1 0 RanBP1 domain NPBW PF15180.6 RJW73862.1 - 0.21 11.4 4.0 0.091 12.6 0.3 2.3 3 0 0 3 3 3 0 Neuropeptides B and W Pox_T4_N PF04491.12 RJW73862.1 - 0.3 11.0 0.8 0.57 10.1 0.8 1.4 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus TFIIA PF03153.13 RJW73862.1 - 0.33 10.9 25.1 0.32 10.9 9.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 RJW73862.1 - 8 5.0 15.0 0.4 9.3 3.7 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup TH1 PF04858.13 RJW73864.1 - 8.8e-82 275.6 0.2 2e-67 228.2 0.0 2.0 2 0 0 2 2 2 2 TH1 protein zf-LITAF-like PF10601.9 RJW73865.1 - 1.1e-23 83.2 7.9 1.5e-23 82.9 7.9 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Prok-RING_4 PF14447.6 RJW73865.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RJW73865.1 - 3.5 7.6 11.7 0.9 9.4 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MMM1 PF10296.9 RJW73867.1 - 0.00032 19.8 1.4 0.0025 16.9 0.0 2.5 3 0 0 3 3 3 1 Maintenance of mitochondrial morphology protein 1 Phage_holin_3_6 PF07332.11 RJW73867.1 - 4.6 7.3 9.0 8.6 6.4 9.0 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RVT_1 PF00078.27 RJW73868.1 - 2.4e-06 27.2 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 RJW73870.1 - 1.5e-25 90.1 0.0 1.6e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW73870.1 - 1.3e-09 37.7 0.0 1.5e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FAT PF02259.23 RJW73873.1 - 1.5e-14 54.0 2.7 3.8e-13 49.4 0.1 3.5 3 1 0 3 3 3 2 FAT domain MFS_1 PF07690.16 RJW73875.1 - 7.9e-24 84.2 21.9 2.6e-16 59.5 21.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4694 PF15765.5 RJW73875.1 - 0.11 12.5 0.3 0.18 11.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4694) HEAT PF02985.22 RJW73876.1 - 1.5e-36 121.3 25.7 0.0012 18.9 0.1 13.2 14 0 0 14 14 13 9 HEAT repeat HEAT_2 PF13646.6 RJW73876.1 - 6.9e-33 112.9 9.9 6.7e-12 45.6 0.0 7.5 1 1 7 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.7 RJW73876.1 - 3.5e-11 43.6 0.0 0.016 15.8 0.0 6.1 5 2 1 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RJW73876.1 - 4e-11 43.2 1.1 0.0048 17.0 0.1 5.3 2 1 4 6 6 6 4 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 RJW73876.1 - 2.6e-07 30.5 0.1 0.0085 15.7 0.0 4.8 2 2 3 5 5 5 1 CLASP N terminal Adaptin_N PF01602.20 RJW73876.1 - 1.3e-06 27.3 4.7 0.0056 15.3 0.0 3.2 2 1 1 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 RJW73876.1 - 0.00033 21.1 16.1 5.4 7.6 2.2 7.8 6 3 2 8 8 8 1 HEAT-like repeat RTP1_C1 PF10363.9 RJW73876.1 - 0.0016 18.6 1.2 0.96 9.7 0.0 4.6 4 2 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 RJW73876.1 - 0.46 10.9 5.0 13 6.2 0.1 4.4 3 1 2 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SRR1 PF07985.12 RJW73876.1 - 0.67 10.0 3.8 1.3 9.1 2.5 2.2 2 0 0 2 2 2 0 SRR1 HEAT_PBS PF03130.16 RJW73876.1 - 4.1 8.3 8.7 45 5.1 0.0 4.8 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Zip PF02535.22 RJW73877.1 - 2.8e-41 141.9 10.4 1e-40 140.0 10.4 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Scs3p PF10261.9 RJW73878.1 - 1.8e-27 96.4 14.1 4.2e-27 95.2 14.1 1.6 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM UPF0172 PF03665.13 RJW73879.1 - 4.3e-20 72.6 0.5 2.5e-17 63.6 0.5 2.2 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0172) DSPc PF00782.20 RJW73881.1 - 6.8e-35 119.8 0.0 1.1e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RJW73881.1 - 0.00017 21.3 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Flagellin_IN PF07196.13 RJW73881.1 - 0.031 14.4 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif Aminotran_1_2 PF00155.21 RJW73883.1 - 3.5e-34 118.5 0.0 4.3e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Limkain-b1 PF11608.8 RJW73883.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 Gp_dh_C PF02800.20 RJW73883.1 - 0.087 12.4 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Aminotran_MocR PF12897.7 RJW73883.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 RJW73883.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase EF-hand_7 PF13499.6 RJW73884.1 - 5.5e-29 100.4 0.5 1.9e-16 60.3 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RJW73884.1 - 3.1e-26 88.9 2.1 3.4e-07 29.4 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RJW73884.1 - 1.2e-20 71.5 1.0 0.00032 20.4 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RJW73884.1 - 4.3e-20 71.3 0.7 1.9e-07 30.8 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RJW73884.1 - 5.1e-19 66.8 0.2 1e-05 24.8 0.0 4.2 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 RJW73884.1 - 1e-09 38.7 0.0 0.0003 21.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RJW73884.1 - 2.7e-07 30.8 0.0 0.028 14.8 0.0 2.7 1 1 2 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 RJW73884.1 - 7e-07 29.1 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RJW73884.1 - 0.13 12.5 0.0 4.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain PriCT_1 PF08708.11 RJW73884.1 - 0.17 11.7 0.1 0.47 10.2 0.0 1.6 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) EF-hand_7 PF13499.6 RJW73885.1 - 4.5e-23 81.5 0.6 2.8e-11 43.7 0.0 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RJW73885.1 - 1e-22 77.9 0.6 5.4e-05 22.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RJW73885.1 - 4.5e-18 63.6 0.4 6.4e-05 22.6 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RJW73885.1 - 1.3e-15 57.0 0.1 0.0029 17.4 0.0 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RJW73885.1 - 9e-15 53.4 3.1 0.0077 15.7 0.0 4.7 4 1 1 5 5 5 4 EF hand SPARC_Ca_bdg PF10591.9 RJW73885.1 - 1.8e-07 31.5 0.0 0.0012 19.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 RJW73885.1 - 0.00024 21.9 0.0 0.089 13.7 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 RJW73885.1 - 0.0011 19.1 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 2 Dockerin type I domain EF-hand_9 PF14658.6 RJW73885.1 - 0.0014 18.9 0.0 0.027 14.8 0.0 2.5 2 1 1 3 3 3 1 EF-hand domain DUF5580 PF17743.1 RJW73885.1 - 0.025 13.1 0.0 0.18 10.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 RJW73885.1 - 0.027 14.8 0.0 5.7 7.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 RJW73885.1 - 0.036 14.0 0.1 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 RJW73885.1 - 0.15 12.0 0.0 27 4.6 0.0 2.7 2 1 2 4 4 4 0 Caleosin related protein PDCD9 PF07147.12 RJW73886.1 - 3.5e-24 85.9 0.1 7.2e-22 78.2 0.1 2.8 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) UCH PF00443.29 RJW73887.1 - 2.3e-39 135.5 0.0 6.9e-39 133.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RJW73887.1 - 1.3e-26 94.0 0.0 6.1e-26 91.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 RJW73887.1 - 0.00044 20.1 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Med26 PF08711.11 RJW73889.1 - 0.065 13.3 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain RT_RNaseH_2 PF17919.1 RJW73890.1 - 1.7e-38 130.7 0.0 3.4e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW73890.1 - 5.5e-35 119.8 0.0 1.2e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RJW73890.1 - 8.9e-24 84.2 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RJW73890.1 - 2.3e-22 79.4 0.0 5.3e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RJW73890.1 - 1.9e-12 47.1 0.1 1.9e-12 47.1 0.1 1.9 2 0 0 2 2 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RJW73890.1 - 3.5e-06 27.1 0.0 3.5e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 RJW73890.1 - 5.9e-05 22.8 0.0 0.0002 21.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 RJW73890.1 - 0.0032 18.0 0.0 0.0072 16.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 RJW73890.1 - 0.006 16.8 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein RVP PF00077.20 RJW73890.1 - 0.026 14.8 0.0 0.069 13.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 RJW73890.1 - 0.053 14.2 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Sulfatase_C PF14707.6 RJW73891.1 - 0.025 15.3 0.6 0.075 13.8 0.6 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4298 PF14131.6 RJW73891.1 - 0.22 11.5 1.7 0.47 10.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF4201 PF13870.6 RJW73891.1 - 7.6 6.2 27.6 0.077 12.7 18.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Pribosyltran PF00156.27 RJW73893.1 - 2e-07 30.6 0.0 2.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RJW73893.1 - 0.00022 20.8 0.0 0.00025 20.6 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 RJW73893.1 - 0.0021 17.6 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase DUF4781 PF16013.5 RJW73893.1 - 0.069 12.0 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) RVT_1 PF00078.27 RJW73895.1 - 5.9e-45 153.5 0.0 9.2e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RJW73895.1 - 3.7e-07 30.0 0.0 1.1e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RJW73895.1 - 6e-07 29.2 0.8 2.2e-06 27.4 0.3 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family EF-hand_1 PF00036.32 RJW73896.1 - 1.3e-26 90.1 3.1 2.6e-05 23.4 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RJW73896.1 - 2.8e-24 85.4 1.2 2e-11 44.1 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RJW73896.1 - 2.1e-21 74.4 3.5 8.6e-05 21.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RJW73896.1 - 8.6e-21 72.1 4.1 6.9e-05 22.5 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RJW73896.1 - 1.4e-13 50.5 4.0 0.0002 21.1 0.8 3.9 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW73896.1 - 7.8e-07 29.4 0.1 0.013 15.8 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW73896.1 - 8.2e-06 25.7 0.4 0.0072 16.3 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RJW73896.1 - 0.0013 18.9 1.0 0.92 9.8 0.1 3.2 3 1 0 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 RJW73896.1 - 0.0023 17.9 0.3 3.7 7.4 0.0 3.3 1 1 2 3 3 3 2 Caleosin related protein Toprim_2 PF13155.6 RJW73896.1 - 0.0055 17.1 0.2 4.6 7.7 0.0 2.5 2 1 1 3 3 3 2 Toprim-like EF-hand_10 PF14788.6 RJW73896.1 - 0.059 13.2 0.3 6.5 6.7 0.0 3.2 4 0 0 4 4 4 0 EF hand Ribonuclease PF00545.20 RJW73896.1 - 0.077 13.8 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 ribonuclease EF-hand_1 PF00036.32 RJW73898.1 - 1.6e-31 105.5 15.9 9.8e-06 24.8 0.0 6.2 6 0 0 6 6 6 6 EF hand EF-hand_5 PF13202.6 RJW73898.1 - 3.7e-29 98.9 12.6 4e-07 29.2 0.0 6.3 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 RJW73898.1 - 1.4e-27 95.9 11.1 7.2e-10 39.2 0.1 4.1 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RJW73898.1 - 2.5e-24 83.1 14.3 1.7e-05 24.4 0.1 6.2 6 0 0 6 6 6 5 EF-hand domain EF-hand_8 PF13833.6 RJW73898.1 - 2.3e-20 72.2 20.4 3.2e-09 36.5 1.7 5.6 3 3 3 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW73898.1 - 3.5e-12 46.6 4.2 0.00012 22.3 0.3 3.1 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RJW73898.1 - 0.00069 19.5 6.2 1.5 8.8 0.3 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RJW73898.1 - 0.002 18.4 0.4 2.2 8.7 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 RJW73898.1 - 0.0063 16.7 6.7 1 9.6 0.0 4.3 4 1 1 5 5 5 2 Dockerin type I domain Caleosin PF05042.13 RJW73898.1 - 0.0098 15.8 3.3 26 4.7 0.0 4.8 2 2 4 6 6 6 0 Caleosin related protein DUF2789 PF10982.8 RJW73898.1 - 0.01 16.0 0.6 0.11 12.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2789) YflT PF11181.8 RJW73898.1 - 0.048 14.2 0.2 17 6.0 0.0 2.3 2 0 0 2 2 2 0 Heat induced stress protein YflT EF-hand_11 PF08976.11 RJW73898.1 - 0.058 14.3 0.0 0.33 11.8 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain VCBS PF13517.6 RJW73898.1 - 0.95 10.1 0.0 0.95 10.1 0.0 3.6 4 1 0 4 4 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FH2 PF02181.23 RJW73900.1 - 1e-69 235.5 2.9 4.5e-69 233.3 2.9 2.1 1 1 0 1 1 1 1 Formin Homology 2 Domain Formin_GBD_N PF18382.1 RJW73900.1 - 6.1e-12 45.9 0.2 2.1e-11 44.2 0.2 2.0 1 0 0 1 1 1 1 Formin N-terminal GTPase-binding domain PDZ PF00595.24 RJW73901.1 - 7e-11 42.3 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 RJW73901.1 - 2.2e-08 34.2 3.9 3.4e-08 33.6 3.9 1.3 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 RJW73901.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 RJW73901.1 - 0.00033 21.7 0.0 0.00069 20.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ_2 PF13180.6 RJW73901.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain JAB PF01398.21 RJW73902.1 - 2.2e-32 111.5 0.0 3.7e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RJW73902.1 - 2.5e-30 105.2 0.3 4.1e-30 104.5 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Atg31 PF09795.9 RJW73902.1 - 0.055 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Autophagy-related protein 31 NARG2_C PF10505.9 RJW73905.1 - 1.6e-15 57.2 0.0 3.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Btz PF09405.10 RJW73907.1 - 3.2e-16 59.8 3.6 1.9e-15 57.3 3.6 2.3 1 1 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding VHL PF01847.16 RJW73908.1 - 0.031 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 VHL beta domain RVT_1 PF00078.27 RJW73910.1 - 7.2e-46 156.5 0.3 1.6e-45 155.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 RJW73910.1 - 1.4e-25 89.2 0.1 9.5e-25 86.6 0.0 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RJW73910.1 - 9.8e-24 83.7 0.0 2.8e-23 82.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Exo_endo_phos_2 PF14529.6 RJW73910.1 - 6.8e-12 45.3 0.1 1.1e-10 41.3 0.0 3.3 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase PrmA PF06325.13 RJW73910.1 - 0.00021 20.8 0.1 0.00036 20.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 RJW73910.1 - 0.027 15.1 0.1 0.12 13.1 0.1 2.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 RJW73910.1 - 0.045 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RJW73910.1 - 0.058 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 RJW73910.1 - 0.15 11.8 0.0 8.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Lysine methyltransferase Ig_3 PF13927.6 RJW73911.1 - 1.5e-25 89.6 1.4 1.3e-13 51.3 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 RJW73911.1 - 1.6e-25 89.0 0.0 4e-14 52.4 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain fn3 PF00041.21 RJW73911.1 - 1.3e-23 83.1 4.6 1.1e-13 51.4 0.2 2.9 3 1 0 3 3 3 2 Fibronectin type III domain Ig_2 PF13895.6 RJW73911.1 - 1e-13 51.4 0.2 6.4e-07 29.6 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 RJW73911.1 - 5.4e-13 48.9 0.1 5.4e-08 32.9 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RJW73911.1 - 3.1e-06 27.3 0.7 0.12 12.5 0.2 3.8 2 2 0 2 2 2 2 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 RJW73911.1 - 0.002 18.6 3.7 0.55 10.8 0.1 3.4 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain LLGL PF08366.13 RJW73912.1 - 4.5e-07 30.2 0.1 9.4e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 LLGL2 Synaptobrevin PF00957.21 RJW73912.1 - 7.3e-05 22.5 0.2 0.00012 21.8 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin WD40 PF00400.32 RJW73912.1 - 0.0011 19.7 0.2 0.019 15.8 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Pkinase PF00069.25 RJW73913.1 - 5.7e-48 163.6 0.0 3e-47 161.2 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RJW73913.1 - 6.1e-18 65.0 0.0 8.8e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RJW73913.1 - 0.00071 18.6 0.0 0.00094 18.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RJW73913.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RJW73913.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RJW73913.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AMP-binding_C PF13193.6 RJW73913.1 - 0.15 13.1 0.0 0.39 11.7 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Aldedh PF00171.22 RJW73914.1 - 0.0029 16.2 0.0 0.0093 14.5 0.0 1.8 2 0 0 2 2 2 1 Aldehyde dehydrogenase family Ribosomal_S5 PF00333.20 RJW73915.1 - 1.2e-15 57.2 1.2 2.2e-15 56.4 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 RJW73915.1 - 3.2e-14 52.1 0.7 1.2e-13 50.3 0.0 2.2 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Innexin PF00876.18 RJW73917.1 - 4.3e-75 253.2 3.6 5e-75 253.0 3.6 1.1 1 0 0 1 1 1 1 Innexin Y_phosphatase PF00102.27 RJW73919.1 - 6.9e-158 523.3 0.4 5.5e-81 271.6 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 RJW73919.1 - 2.5e-32 111.0 4.2 5.4e-14 52.3 0.2 7.3 7 2 0 7 7 7 4 Fibronectin type III domain DSPc PF00782.20 RJW73919.1 - 2.1e-08 34.1 0.0 0.0016 18.3 0.1 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Pur_ac_phosph_N PF16656.5 RJW73919.1 - 2.2e-07 31.3 3.3 0.36 11.4 0.2 4.3 4 0 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain Y_phosphatase3 PF13350.6 RJW73919.1 - 2.6e-06 27.6 0.0 0.096 12.6 0.0 2.6 3 0 0 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 RJW73919.1 - 0.00051 20.2 0.6 0.27 11.3 0.1 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate fn3_4 PF16794.5 RJW73919.1 - 0.0015 18.4 0.0 0.21 11.5 0.0 3.6 3 0 0 3 3 3 1 Fibronectin-III type domain Adeno_E3_CR2 PF02439.15 RJW73919.1 - 0.5 10.2 3.6 1.3 8.9 3.6 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Death_2 PF14786.6 RJW73921.1 - 0.15 11.9 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Tube Death domain AMP-binding PF00501.28 RJW73923.1 - 7.4e-65 219.2 0.0 1.1e-64 218.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RJW73923.1 - 2.7e-14 53.9 0.6 6.6e-14 52.6 0.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 RJW73927.1 - 6.4e-19 68.0 9.6 1.5e-10 41.4 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73927.1 - 2.6e-05 24.4 0.0 0.034 14.4 0.0 3.5 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW73927.1 - 0.026 13.5 0.0 0.092 11.7 0.0 1.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 RJW73927.1 - 0.046 14.2 0.0 3.8 8.1 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain DUF667 PF05018.13 RJW73928.1 - 2.1e-92 308.0 1.4 2.3e-92 307.8 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) WD40 PF00400.32 RJW73930.1 - 7.3e-16 58.3 12.7 0.00044 21.0 0.2 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 RJW73930.1 - 8.5e-10 38.8 0.0 2.1e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pkinase PF00069.25 RJW73932.1 - 2e-42 145.4 0.0 1.4e-24 86.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RJW73932.1 - 6.5e-21 74.8 0.0 9.7e-11 41.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RJW73932.1 - 0.016 14.5 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like WD40 PF00400.32 RJW73933.1 - 1.7e-41 139.4 14.5 6.3e-07 30.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW73933.1 - 2.9e-11 43.5 0.1 0.59 10.5 0.0 5.2 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RJW73933.1 - 2.1e-05 23.7 0.1 0.81 8.6 0.0 3.9 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RJW73933.1 - 0.0013 17.5 1.5 5.7 5.5 0.0 3.6 2 1 1 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 RJW73933.1 - 0.086 12.8 3.5 16 5.6 0.1 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 RJW73933.1 - 0.13 12.8 0.2 48 4.6 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain M64_N PF16217.5 RJW73933.1 - 0.16 11.5 0.0 46 3.6 0.0 3.2 3 0 0 3 3 3 0 Peptidase M64 N-terminus Lectin_C PF00059.21 RJW73934.1 - 0.023 15.4 0.0 0.028 15.1 0.0 1.1 1 0 0 1 1 1 0 Lectin C-type domain MIF4G_like_2 PF09090.11 RJW73935.1 - 6.9e-34 117.5 0.1 4.2e-31 108.4 0.0 2.4 2 0 0 2 2 2 2 MIF4G like MIF4G_like PF09088.11 RJW73935.1 - 2.6e-27 95.9 0.6 2.2e-25 89.6 0.1 2.4 1 1 1 2 2 2 2 MIF4G like adh_short PF00106.25 RJW73936.1 - 3e-43 147.6 0.0 6.5e-43 146.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RJW73936.1 - 3.7e-26 92.1 0.0 5.5e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RJW73936.1 - 5.1e-08 33.0 0.0 1.4e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RJW73936.1 - 0.0097 15.4 0.0 0.032 13.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RJW73936.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 RJW73936.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 RJW73936.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EF-hand_1 PF00036.32 RJW73937.1 - 7.5e-34 112.8 14.4 2.4e-06 26.7 0.1 6.2 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 RJW73937.1 - 2.5e-30 101.8 11.7 4e-06 26.3 0.2 6.2 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.6 RJW73937.1 - 8.6e-30 103.0 8.0 6e-10 39.4 0.6 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RJW73937.1 - 5.3e-23 79.4 17.9 4e-06 26.1 0.2 6.3 6 1 0 6 6 6 5 EF hand SPARC_Ca_bdg PF10591.9 RJW73937.1 - 2.3e-15 56.9 2.8 0.00045 20.5 0.0 3.1 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 RJW73937.1 - 4.4e-15 55.3 8.7 0.0012 18.6 0.0 5.3 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_4 PF12763.7 RJW73937.1 - 4.4e-06 26.6 8.7 0.79 9.7 0.6 4.8 1 1 4 5 5 5 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RJW73937.1 - 8.2e-06 26.1 0.1 0.35 11.2 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain EF-hand_10 PF14788.6 RJW73937.1 - 5.7e-05 22.9 2.5 0.11 12.3 0.0 4.1 5 0 0 5 5 5 2 EF hand Dockerin_1 PF00404.18 RJW73937.1 - 0.00012 22.2 0.6 18 5.6 0.0 4.6 4 1 0 4 4 4 0 Dockerin type I domain PsbU PF06514.11 RJW73937.1 - 0.028 14.4 0.3 0.21 11.6 0.2 2.2 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) NeA_P2 PF12312.8 RJW73937.1 - 0.038 13.4 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Toprim_2 PF13155.6 RJW73937.1 - 0.11 12.9 0.3 2.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Toprim-like DUF5077 PF16871.5 RJW73938.1 - 0.053 13.4 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) LRR_4 PF12799.7 RJW73940.1 - 5.7e-17 61.6 22.7 1.4e-06 28.6 1.7 4.5 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RJW73940.1 - 1.2e-15 56.9 42.8 2.9e-07 30.2 6.0 4.0 2 1 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 RJW73940.1 - 6.4e-07 29.0 8.8 6.3e-05 22.6 3.1 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 RJW73940.1 - 0.00039 20.6 24.1 1.6 9.6 0.1 6.7 7 1 0 7 7 7 4 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 RJW73940.1 - 0.044 13.8 1.2 2.6 8.1 0.0 3.8 4 1 0 5 5 5 0 RsmF rRNA methyltransferase first C-terminal domain STAT1_TAZ2bind PF12162.8 RJW73940.1 - 0.1 12.2 0.5 0.57 9.8 0.1 2.2 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain ig PF00047.25 RJW73941.1 - 2.8e-08 33.8 0.7 6.2e-05 23.1 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 RJW73941.1 - 1.4e-07 32.0 2.2 0.00032 21.2 0.2 2.6 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RJW73941.1 - 1.7e-06 28.2 0.1 0.00092 19.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 RJW73941.1 - 4.4e-06 26.7 0.4 1.5e-05 24.9 0.0 2.1 3 0 0 3 3 3 1 Immunoglobulin I-set domain Izumo-Ig PF16706.5 RJW73941.1 - 0.036 14.1 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RJW73941.1 - 0.06 12.9 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.6 RJW73941.1 - 0.13 12.6 0.2 0.75 10.2 0.0 2.2 2 1 0 2 2 2 0 Immunoglobulin domain bZIP_Maf PF03131.17 RJW73942.1 - 9.8e-06 26.0 7.8 1.6e-05 25.3 7.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 RJW73942.1 - 0.095 12.8 13.8 0.21 11.7 12.3 2.3 2 1 1 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.15 RJW73942.1 - 0.099 12.7 9.8 0.21 11.7 9.8 1.5 1 0 0 1 1 1 0 Basic region leucine zipper US30 PF17624.2 RJW73942.1 - 0.86 8.6 5.0 1.7 7.6 5.0 1.4 1 0 0 1 1 1 0 Family of unknown function RVT_1 PF00078.27 RJW73943.1 - 0.0061 16.1 0.0 0.029 13.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4614 PF15391.6 RJW73944.1 - 4.3e-11 43.1 3.6 4.3e-11 43.1 3.6 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4614) Haspin_kinase PF12330.8 RJW73947.1 - 7.4e-23 81.1 0.0 8.4e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Haspin like kinase domain FERM_C PF09380.10 RJW73948.1 - 3.9e-23 81.6 0.0 7.3e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RJW73948.1 - 2.6e-21 76.2 0.0 2.6e-21 76.2 0.0 2.8 3 1 1 4 4 4 1 FERM central domain ERM PF00769.19 RJW73948.1 - 5.9e-08 32.8 0.9 5.9e-08 32.8 0.9 3.0 2 1 1 3 3 3 1 Ezrin/radixin/moesin family tRNA-synt_1d PF00750.19 RJW73948.1 - 0.15 11.0 1.3 0.28 10.1 1.3 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (R) DUF724 PF05266.14 RJW73948.1 - 3.1 7.6 15.6 1.2 8.9 8.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 RJW73948.1 - 6.2 4.6 11.7 8.9 4.1 11.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EF-hand_1 PF00036.32 RJW73949.1 - 1.8e-35 117.8 20.4 7.8e-06 25.1 1.0 6.2 6 0 0 6 6 6 6 EF hand EF-hand_5 PF13202.6 RJW73949.1 - 1.7e-31 106.3 12.9 3.6e-06 26.2 0.1 6.2 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 RJW73949.1 - 3e-31 104.6 18.2 7.4e-06 25.5 1.8 6.1 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.6 RJW73949.1 - 8.9e-30 103.0 13.3 1.7e-10 41.2 0.2 3.7 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 RJW73949.1 - 9.2e-17 60.6 15.6 6e-06 26.0 2.5 5.2 4 2 2 6 6 6 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RJW73949.1 - 8.8e-14 51.8 7.9 0.00028 21.2 0.1 3.1 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 RJW73949.1 - 2.2e-08 34.1 0.5 0.55 10.5 1.1 4.9 4 1 1 5 5 5 1 Dockerin type I domain EF-hand_11 PF08976.11 RJW73949.1 - 0.0016 19.3 0.5 3.9 8.4 0.0 3.1 1 1 2 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 RJW73949.1 - 0.0028 17.6 9.1 2.1 8.3 0.5 3.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand FYRC PF05965.14 RJW73949.1 - 0.0059 16.7 0.1 0.02 15.1 0.0 1.9 2 1 0 2 2 2 1 F/Y rich C-terminus EF-hand_9 PF14658.6 RJW73949.1 - 0.0061 16.9 3.0 0.34 11.3 0.0 3.0 3 1 0 3 3 3 1 EF-hand domain PMBR PF09373.10 RJW73949.1 - 0.0076 16.4 0.5 11 6.3 0.0 4.3 4 0 0 4 4 4 0 Pseudomurein-binding repeat EF-hand_10 PF14788.6 RJW73949.1 - 0.038 13.8 3.7 58 3.7 0.0 4.8 4 1 1 5 5 5 0 EF hand NADPH_Ox PF08414.10 RJW73949.1 - 0.051 13.9 0.1 0.32 11.4 0.1 2.4 1 1 0 1 1 1 0 Respiratory burst NADPH oxidase Toprim_2 PF13155.6 RJW73949.1 - 0.12 12.8 0.4 1 9.8 0.0 2.5 1 1 1 2 2 2 0 Toprim-like EF-hand_14 PF17959.1 RJW73949.1 - 0.14 12.5 3.1 20 5.6 2.1 2.9 2 1 0 2 2 2 0 EF-hand domain Ank_2 PF12796.7 RJW73950.1 - 6.9e-202 654.7 69.9 7.1e-18 65.0 0.1 11.7 2 1 14 16 16 16 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RJW73950.1 - 2.5e-145 471.2 66.1 1.3e-14 54.3 0.2 15.8 5 4 12 18 18 18 18 Ankyrin repeats (many copies) Ank PF00023.30 RJW73950.1 - 5.7e-137 440.8 65.3 9.5e-10 38.5 0.1 23.3 22 2 1 23 23 23 22 Ankyrin repeat Ank_5 PF13857.6 RJW73950.1 - 1.2e-129 420.6 49.0 2e-11 43.9 0.1 19.2 3 3 15 19 19 19 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 RJW73950.1 - 2.9e-115 362.1 46.9 3.7e-06 26.9 0.0 23.9 24 0 0 24 24 24 21 Ankyrin repeat ZU5 PF00791.20 RJW73950.1 - 1.2e-24 86.4 0.0 1.7e-23 82.8 0.0 2.6 2 0 0 2 2 2 1 ZU5 domain Imm_superinfect PF14373.6 RJW73950.1 - 1.2 9.1 3.1 69 3.5 0.0 5.4 6 0 0 6 6 6 0 Superinfection immunity protein VIR_N PF15912.5 RJW73952.1 - 3.6e-25 89.1 1.1 8.2e-25 87.9 1.1 1.5 1 0 0 1 1 1 1 Virilizer, N-terminal SHIPPO-rpt PF07004.12 RJW73955.1 - 6.8e-07 29.9 2.4 2.5 9.1 0.2 4.4 4 0 0 4 4 4 4 Sperm-tail PG-rich repeat PAXNEB PF05625.11 RJW73956.1 - 5.8e-41 140.9 0.0 7e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein SURF4 PF02077.15 RJW73957.1 - 0.028 14.0 0.1 0.038 13.6 0.1 1.1 1 0 0 1 1 1 0 SURF4 family NuA4 PF09340.10 RJW73957.1 - 0.098 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 RVT_1 PF00078.27 RJW73958.1 - 1e-44 152.7 0.0 1.7e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SPRY PF00622.28 RJW73958.1 - 2.8e-17 63.0 0.3 6.2e-17 61.8 0.3 1.7 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 RJW73958.1 - 1.1e-12 48.0 0.0 1.1e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Exo_endo_phos PF03372.23 RJW73958.1 - 0.00033 20.3 0.6 0.00079 19.0 0.6 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IMD PF08397.11 RJW73962.1 - 4.5e-39 134.1 3.4 9.9e-38 129.7 3.4 2.2 1 1 0 1 1 1 1 IRSp53/MIM homology domain RVT_1 PF00078.27 RJW73962.1 - 0.0037 16.8 0.0 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Branch PF02485.21 RJW73963.1 - 1.8e-30 106.3 0.8 3.3e-30 105.4 0.0 1.8 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Xylo_C PF12529.8 RJW73963.1 - 3.6e-06 26.7 0.0 8.3e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Xylosyltransferase C terminal WSC PF01822.19 RJW73963.1 - 9.3e-06 25.8 1.3 3.1e-05 24.1 1.3 1.9 1 0 0 1 1 1 1 WSC domain Rota_NSP3 PF01665.16 RJW73963.1 - 0.048 12.8 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 His_Phos_2 PF00328.22 RJW73965.1 - 3.3e-108 362.4 0.0 4.5e-108 362.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 RJW73965.1 - 7.1e-40 135.1 0.1 1.5e-39 134.0 0.1 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 RJW73965.1 - 2.7e-05 23.9 0.0 5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain FAD_binding_1 PF00667.20 RJW73966.1 - 0.017 14.7 1.3 0.022 14.3 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain CCDC154 PF15450.6 RJW73967.1 - 0.084 11.4 0.1 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Ribosomal_L21p PF00829.21 RJW73968.1 - 6.3e-20 71.3 0.0 1.1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein zf-C2H2 PF00096.26 RJW73969.1 - 1.6e-24 84.9 29.7 2.6e-06 27.6 0.9 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW73969.1 - 8.5e-20 69.8 30.7 0.00042 20.9 0.6 6.6 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RJW73969.1 - 1.5e-15 56.8 35.0 0.00016 21.9 3.8 6.9 8 0 0 8 8 5 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RJW73969.1 - 1.3e-07 31.7 15.9 0.44 10.9 0.0 5.5 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RJW73969.1 - 1.3e-06 28.2 25.7 0.018 15.0 0.9 5.8 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RJW73969.1 - 1.7e-06 27.6 26.3 0.25 11.1 0.3 5.6 5 0 0 5 5 5 4 zinc-finger C2H2-type zf-Di19 PF05605.12 RJW73969.1 - 0.0013 19.0 20.2 0.0093 16.2 2.0 4.8 2 1 3 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 RJW73969.1 - 0.0023 17.9 26.5 0.45 10.6 0.1 5.4 2 2 3 5 5 5 2 BED zinc finger zinc_ribbon_15 PF17032.5 RJW73969.1 - 0.0075 17.0 12.4 0.22 12.3 1.2 3.2 4 0 0 4 4 2 2 zinc-ribbon family zinc_ribbon_9 PF14369.6 RJW73969.1 - 0.019 15.2 5.8 5.2 7.4 0.0 5.0 4 0 0 4 4 4 0 zinc-ribbon zf-met PF12874.7 RJW73969.1 - 0.024 15.0 22.8 1.2 9.7 0.3 5.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 RJW73969.1 - 0.038 13.6 10.6 3.2 7.4 0.1 5.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 RJW73969.1 - 0.063 13.3 0.5 0.063 13.3 0.5 3.7 2 1 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 RJW73969.1 - 0.071 13.2 22.1 0.072 13.2 1.0 4.8 4 2 2 6 6 4 0 Zinc ribbon domain XPA_N PF01286.18 RJW73969.1 - 0.082 13.0 14.4 3.6 7.7 0.1 5.2 5 0 0 5 5 5 0 XPA protein N-terminal Elf1 PF05129.13 RJW73969.1 - 0.16 12.0 8.2 5.4 7.1 2.4 3.2 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.7 RJW73969.1 - 0.2 11.7 20.2 67 3.6 0.2 4.7 2 1 1 3 3 3 0 Double zinc ribbon TerY_C PF15616.6 RJW73969.1 - 0.34 11.0 6.6 0.35 11.0 0.7 2.6 2 0 0 2 2 2 0 TerY-C metal binding domain zf-C2HC_2 PF13913.6 RJW73969.1 - 0.43 10.5 24.6 1.9 8.5 1.5 5.5 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-AN1 PF01428.16 RJW73969.1 - 0.99 9.6 14.3 14 6.0 0.5 5.7 5 0 0 5 5 5 0 AN1-like Zinc finger A2L_zn_ribbon PF08792.10 RJW73969.1 - 1.5 8.6 5.9 13 5.6 0.1 3.5 3 0 0 3 3 3 0 A2L zinc ribbon domain PknG_rubred PF16919.5 RJW73969.1 - 2.6 8.2 9.1 0.76 9.9 0.5 3.3 1 1 2 3 3 3 0 Protein kinase G rubredoxin domain Ogr_Delta PF04606.12 RJW73969.1 - 4.3 7.4 19.5 0.51 10.4 0.6 4.2 4 0 0 4 4 3 0 Ogr/Delta-like zinc finger CpXC PF14353.6 RJW73969.1 - 4.9 7.2 14.3 2 8.5 0.1 4.3 2 2 1 3 3 3 0 CpXC protein Zn_ribbon_SprT PF17283.2 RJW73969.1 - 6.9 6.7 24.0 3.7 7.5 2.5 4.6 3 1 0 3 3 3 0 SprT-like zinc ribbon domain C1_4 PF07975.12 RJW73969.1 - 7.6 6.8 19.4 1.4 9.2 1.7 4.6 4 1 1 5 5 4 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.7 RJW73969.1 - 8.3 6.5 27.8 28 4.8 4.0 4.5 1 1 3 4 4 4 0 Transposase zinc-ribbon domain DUF2256 PF10013.9 RJW73969.1 - 10 6.4 14.3 8.3 6.6 0.0 5.2 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) EF-hand_8 PF13833.6 RJW73971.1 - 0.00015 21.6 0.1 0.00027 20.7 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 RJW73971.1 - 0.0002 21.7 0.1 0.00064 20.1 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RJW73971.1 - 0.0023 17.3 0.3 0.0043 16.5 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RJW73971.1 - 0.022 14.6 0.2 0.056 13.4 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain Innexin PF00876.18 RJW73972.1 - 1.4e-45 156.1 1.0 1.6e-45 155.9 1.0 1.0 1 0 0 1 1 1 1 Innexin Brix PF04427.18 RJW73973.1 - 6.1e-26 91.7 0.5 9.2e-26 91.1 0.5 1.3 1 0 0 1 1 1 1 Brix domain AMP-binding PF00501.28 RJW73975.1 - 9.4e-69 232.0 0.0 1.2e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 RJW73975.1 - 1.7e-20 72.7 4.0 3.8e-20 71.6 4.0 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 RJW73975.1 - 7e-12 46.2 0.2 7e-12 46.2 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ets PF00178.22 RJW73978.1 - 2.3e-35 120.9 0.3 4.7e-35 119.9 0.3 1.5 1 0 0 1 1 1 1 Ets-domain 7tm_1 PF00001.21 RJW73980.1 - 5.2e-06 26.0 19.5 7.7e-06 25.4 19.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ACC_central PF08326.12 RJW73981.1 - 2e-194 647.9 0.0 1.1e-153 513.2 0.0 2.8 2 1 0 2 2 2 2 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 RJW73981.1 - 8.6e-135 450.1 0.0 9.3e-134 446.7 0.0 2.0 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 RJW73981.1 - 8.8e-49 165.9 0.4 1.7e-48 164.9 0.1 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RJW73981.1 - 2.1e-29 102.3 0.1 9.5e-29 100.2 0.1 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RJW73981.1 - 2.5e-20 72.6 0.0 6.7e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 RJW73981.1 - 1.5e-06 27.9 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 RJW73981.1 - 0.00055 20.0 0.1 0.0022 18.0 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 RJW73981.1 - 0.0083 15.7 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ER_lumen_recept PF00810.18 RJW73982.1 - 2.4e-39 135.5 10.7 2.4e-39 135.5 10.7 2.0 2 1 0 2 2 2 1 ER lumen protein retaining receptor BRE1 PF08647.11 RJW73983.1 - 5e-11 42.5 10.5 5e-11 42.5 10.5 10.1 5 2 3 9 9 9 4 BRE1 E3 ubiquitin ligase NDUF_B6 PF09782.9 RJW73983.1 - 0.62 10.2 4.3 5.2 7.2 0.7 2.7 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF4407 PF14362.6 RJW73983.1 - 2.9 7.1 90.6 0.27 10.5 20.1 6.3 1 1 4 5 5 5 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 RJW73984.1 - 2.1e-16 59.5 0.1 4.1e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RJW73984.1 - 0.00025 21.1 0.0 0.00063 19.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 RJW73984.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.19 RJW73984.1 - 0.48 10.3 14.5 0.8 9.6 14.5 1.2 1 0 0 1 1 1 0 SPX domain DUF3668 PF12416.8 RJW73987.1 - 2e-21 76.9 0.0 4.8e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Cep120 protein DUF4497 PF14924.6 RJW73987.1 - 0.0031 18.0 0.1 0.097 13.1 0.0 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4497) GldM_N PF12081.8 RJW73987.1 - 0.019 15.1 5.2 0.044 13.9 5.2 1.6 1 0 0 1 1 1 0 GldM N-terminal domain C2 PF00168.30 RJW73987.1 - 0.11 12.8 0.0 0.66 10.3 0.0 2.2 2 0 0 2 2 2 0 C2 domain Occludin_ELL PF07303.13 RJW73987.1 - 0.34 11.6 18.3 6.3 7.6 2.5 4.0 3 1 0 3 3 3 0 Occludin homology domain RBD PF02196.15 RJW73988.1 - 5.9e-06 26.3 0.1 1.9e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 RJW73988.1 - 0.0062 16.7 0.1 0.037 14.2 0.0 2.3 2 0 0 2 2 2 1 TUG ubiquitin-like domain CAP_N PF01213.19 RJW73988.1 - 0.0094 15.5 2.7 0.02 14.4 2.7 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PACT_coil_coil PF10495.9 RJW73989.1 - 1.2e-17 64.3 0.0 1.2e-17 64.3 0.0 3.3 4 0 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.9 RJW73989.1 - 4.5e-05 23.5 18.5 4.5e-05 23.5 18.5 7.9 8 2 1 9 9 9 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 RJW73989.1 - 0.78 8.6 54.9 0.031 13.2 15.8 3.9 3 0 0 3 3 3 0 Spc7 kinetochore protein MAD PF05557.13 RJW73989.1 - 8.1 4.7 56.1 0.042 12.2 11.3 3.4 3 0 0 3 3 3 0 Mitotic checkpoint protein Ldl_recept_a PF00057.18 RJW73990.1 - 0.28 11.4 2.3 0.7 10.2 2.3 1.8 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A SHE3 PF17078.5 RJW73993.1 - 0.22 11.2 2.2 0.31 10.7 2.2 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Pol_alpha_B_N PF08418.10 RJW73995.1 - 3.6 7.5 7.2 6 6.8 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RNA_pol_Rpb2_7 PF04560.20 RJW73996.1 - 0.11 12.8 0.1 0.35 11.3 0.1 1.8 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 7 SK_channel PF03530.14 RJW73998.1 - 3.6e-43 146.2 0.4 8.8e-43 145.0 0.4 1.7 1 0 0 1 1 1 1 Calcium-activated SK potassium channel CaMBD PF02888.16 RJW73998.1 - 7e-21 74.2 2.1 2e-20 72.7 2.1 1.9 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 RJW73998.1 - 1.5e-14 53.7 2.0 1.5e-14 53.7 2.0 2.1 2 0 0 2 2 2 1 Ion channel Adenylsucc_synt PF00709.21 RJW73999.1 - 2.4e-167 557.1 0.0 2.8e-167 556.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase BAMBI PF06211.12 RJW74002.1 - 0.099 12.9 10.7 3.6 7.9 10.7 2.4 1 1 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain PAN_1 PF00024.26 RJW74003.1 - 0.0022 17.9 0.8 0.0046 16.9 0.8 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 RJW74003.1 - 0.0038 17.0 1.2 0.0088 15.8 1.2 1.6 1 0 0 1 1 1 1 PAN-like domain Serpin PF00079.20 RJW74004.1 - 3.4e-29 102.3 0.5 4.7e-26 92.0 0.0 2.0 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) CaMBD PF02888.16 RJW74006.1 - 5.1e-07 29.8 1.8 5.1e-07 29.8 1.8 2.2 2 1 0 2 2 2 1 Calmodulin binding domain UPF0242 PF06785.11 RJW74006.1 - 0.021 14.9 0.9 0.023 14.8 0.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2353 PF09789.9 RJW74006.1 - 0.025 14.0 1.3 0.024 14.0 1.3 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Synaptonemal_3 PF15191.6 RJW74006.1 - 0.053 13.3 1.7 0.072 12.9 1.7 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 Tetraspanin PF00335.20 RJW74007.1 - 7.1e-14 52.1 0.9 8.1e-14 51.9 0.9 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF996 PF06195.13 RJW74007.1 - 0.16 12.2 5.5 0.24 11.7 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Cpn60_TCP1 PF00118.24 RJW74010.1 - 6.8e-165 549.4 9.7 7.8e-165 549.2 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Smim3 PF17307.2 RJW74011.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Small integral membrane protein 3 Pro_dh PF01619.18 RJW74012.1 - 2.1e-79 267.1 0.0 2.6e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Dockerin_1 PF00404.18 RJW74012.1 - 0.049 13.8 0.4 2.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Dockerin type I domain SDA1 PF05285.12 RJW74013.1 - 0.0016 17.9 35.0 0.002 17.6 35.0 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RJW74013.1 - 0.13 10.5 38.7 0.16 10.1 38.7 1.1 1 0 0 1 1 1 0 Nop14-like family EzrA PF06160.12 RJW74014.1 - 0.0017 16.6 6.0 0.0017 16.6 6.0 3.0 1 1 2 3 3 3 1 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 RJW74014.1 - 0.0033 17.5 6.9 0.0033 17.5 6.9 3.0 2 1 0 2 2 1 1 TPR/MLP1/MLP2-like protein Mod_r PF07200.13 RJW74014.1 - 0.0059 16.7 4.8 0.0059 16.7 4.8 3.6 2 1 2 4 4 3 1 Modifier of rudimentary (Mod(r)) protein BRE1 PF08647.11 RJW74014.1 - 0.043 13.9 37.0 0.085 12.9 4.3 4.1 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 RJW74014.1 - 0.057 12.8 37.9 1 8.6 5.6 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 RJW74014.1 - 0.2 11.9 11.6 14 6.0 0.4 4.8 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) IFP_35_N PF07334.13 RJW74014.1 - 0.26 11.4 0.1 0.26 11.4 0.1 2.8 3 0 0 3 3 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc7 PF08317.11 RJW74014.1 - 0.37 9.6 36.0 2.8 6.7 7.0 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 RJW74014.1 - 0.73 10.3 36.2 0.084 13.3 9.4 2.5 1 1 1 2 2 2 0 Fez1 Lebercilin PF15619.6 RJW74014.1 - 0.81 9.3 42.6 0.081 12.6 10.6 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease KASH_CCD PF14662.6 RJW74014.1 - 1.6 8.5 38.4 0.15 11.9 1.2 4.2 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 RJW74014.1 - 2.2 7.6 25.7 0.59 9.4 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YebG PF07130.12 RJW74014.1 - 2.2 8.2 6.6 3 7.8 0.1 3.6 3 1 0 3 3 3 0 YebG protein YabA PF06156.13 RJW74014.1 - 2.3 8.9 31.8 0.71 10.5 3.0 4.8 1 1 3 4 4 4 0 Initiation control protein YabA Rab5-bind PF09311.11 RJW74014.1 - 3.2 7.1 35.5 0.37 10.1 8.5 3.5 2 2 2 4 4 4 0 Rabaptin-like protein APG6_N PF17675.1 RJW74014.1 - 5.1 7.6 42.3 0.42 11.1 8.4 3.6 1 1 2 3 3 3 0 Apg6 coiled-coil region ATG16 PF08614.11 RJW74014.1 - 5.1 7.3 39.6 0.78 9.9 7.1 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 RJW74014.1 - 5.5 7.0 38.7 0.27 11.2 8.4 3.7 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.14 RJW74014.1 - 6.8 7.0 32.0 0.33 11.3 3.5 3.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 RJW74014.1 - 6.9 7.2 33.9 1 9.9 4.8 4.9 2 1 2 4 4 4 0 Cell division protein ZapB SYCE1 PF15233.6 RJW74014.1 - 8.3 6.5 38.4 4.6 7.3 9.7 3.2 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Seryl_tRNA_N PF02403.22 RJW74014.1 - 9 6.6 29.6 15 5.9 4.3 4.3 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF1319 PF07028.11 RJW74014.1 - 9.2 6.5 11.5 0.43 10.8 1.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) IFT57 PF10498.9 RJW74014.1 - 9.8 5.0 28.1 0.29 10.1 5.3 3.2 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Exo_endo_phos_2 PF14529.6 RJW74015.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase BPL_N PF09825.9 RJW74016.1 - 1.1e-49 169.5 0.0 1.4e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal PADR1 PF08063.12 RJW74017.1 - 0.14 11.9 0.3 0.23 11.3 0.3 1.3 1 0 0 1 1 1 0 PADR1 (NUC008) domain zf-CW PF07496.15 RJW74018.1 - 0.0096 15.9 0.9 0.67 10.0 0.2 2.4 2 0 0 2 2 2 2 CW-type Zinc Finger Cystatin PF00031.21 RJW74020.1 - 0.052 13.8 0.0 6.4 7.1 0.0 2.7 3 0 0 3 3 3 0 Cystatin domain adh_short_C2 PF13561.6 RJW74021.1 - 1.2e-60 205.0 0.0 1.5e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RJW74021.1 - 9.4e-48 162.3 0.0 1.3e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RJW74021.1 - 4.1e-08 33.3 0.0 5.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 RJW74021.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Synaptobrevin PF00957.21 RJW74022.1 - 2.9e-11 43.0 1.1 4.7e-11 42.3 1.1 1.4 1 0 0 1 1 1 1 Synaptobrevin MgtE PF01769.16 RJW74022.1 - 0.095 13.1 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Divalent cation transporter CorA PF01544.18 RJW74022.1 - 0.22 10.8 0.1 0.22 10.8 0.1 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PWWP PF00855.17 RJW74023.1 - 7.7e-10 39.1 1.4 1.9e-09 37.8 0.4 2.2 2 0 0 2 2 2 1 PWWP domain ADK_lid PF05191.14 RJW74023.1 - 0.025 14.6 0.1 0.29 11.2 0.1 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid Collagen PF01391.18 RJW74025.1 - 6.1e-157 509.5 630.8 3.2e-09 36.4 30.3 20.3 2 2 12 14 14 14 10 Collagen triple helix repeat (20 copies) COLFI PF01410.18 RJW74025.1 - 8.6e-45 152.8 0.0 1.1e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain AbiEi_3 PF11459.8 RJW74027.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system DUF4483 PF14825.6 RJW74028.1 - 2e-32 112.1 0.0 2.9e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) DUF4113 PF13438.6 RJW74028.1 - 3.5 7.8 5.2 7.2 6.8 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) Cystatin PF00031.21 RJW74029.1 - 9.1e-32 109.2 25.8 4.9e-07 29.9 0.3 11.0 11 1 1 12 12 12 8 Cystatin domain Cathelicidins PF00666.17 RJW74029.1 - 3.9e-06 27.1 20.1 0.15 12.3 0.7 8.4 9 0 0 9 9 9 4 Cathelicidin SQAPI PF16845.5 RJW74029.1 - 4.1e-05 23.8 4.9 0.1 13.0 0.1 5.0 5 0 0 5 5 5 2 Aspartic acid proteinase inhibitor Cystatin PF00031.21 RJW74030.1 - 0.00071 19.8 5.9 0.25 11.6 0.0 4.3 4 0 0 4 4 4 2 Cystatin domain Mtp PF03821.16 RJW74033.1 - 1.8e-08 34.3 14.9 0.0013 18.3 2.1 3.2 2 1 1 3 3 3 3 Golgi 4-transmembrane spanning transporter Peptidase_M8 PF01457.16 RJW74034.1 - 9.3e-07 27.9 2.0 1.1e-06 27.7 2.0 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF3261 PF11659.8 RJW74035.1 - 0.045 13.6 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3261) RsdA_SigD_bd PF16751.5 RJW74035.1 - 0.061 13.6 0.4 16 5.9 0.1 3.4 3 1 0 3 3 3 0 Anti-sigma-D factor RsdA to sigma factor binding region zf-H2C2_2 PF13465.6 RJW74036.1 - 8.1e-17 60.8 25.7 2.5e-09 37.1 1.0 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 RJW74036.1 - 2.5e-16 59.1 20.9 2e-06 27.9 1.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW74036.1 - 1.5e-10 41.0 23.1 0.00071 20.2 1.0 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RJW74036.1 - 0.0077 16.0 2.3 0.0077 16.0 2.3 4.6 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RJW74036.1 - 0.054 13.5 13.7 0.92 9.6 1.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4698 PF15769.5 RJW74036.1 - 0.054 12.6 0.6 0.095 11.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) zf-Di19 PF05605.12 RJW74036.1 - 0.082 13.2 13.2 0.93 9.8 4.3 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 RJW74036.1 - 0.13 12.5 6.5 0.79 10.1 1.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 RJW74036.1 - 2.4 8.1 15.5 0.43 10.5 0.2 3.4 1 1 2 3 3 3 0 SprT-like zinc ribbon domain zf-C2H2_2 PF12756.7 RJW74036.1 - 4.4 7.7 9.8 6.7 7.1 1.0 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) BRAP2 PF07576.12 RJW74038.1 - 1.5e-27 95.7 0.1 2.9e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 RJW74038.1 - 2.2e-18 66.3 5.1 5.6e-18 65.0 5.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 RJW74038.1 - 1.7e-08 34.7 6.2 1.7e-08 34.7 6.2 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RJW74038.1 - 8.6e-08 31.9 5.3 8.6e-08 31.9 5.3 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RJW74038.1 - 3.1e-07 30.3 1.7 7.3e-07 29.1 0.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RJW74038.1 - 1.1e-05 25.3 3.6 1.1e-05 25.3 3.6 3.1 4 0 0 4 4 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RJW74038.1 - 1.6e-05 24.7 5.6 5.6e-05 22.9 5.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RJW74038.1 - 4.8e-05 23.0 2.3 0.0002 21.0 2.3 2.2 1 0 0 1 1 1 1 RING-like zinc finger zf-UBP_var PF17807.1 RJW74038.1 - 0.0051 16.6 0.5 0.016 14.9 0.5 1.9 1 0 0 1 1 1 1 Variant UBP zinc finger zf-C3HC4_4 PF15227.6 RJW74038.1 - 0.0056 16.8 2.7 0.0056 16.8 2.7 2.8 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RJW74038.1 - 0.0079 16.5 5.9 0.042 14.1 5.9 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain RRM_1 PF00076.22 RJW74038.1 - 0.026 14.3 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF948 PF06103.11 RJW74038.1 - 0.034 14.4 1.8 0.1 12.9 1.8 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.19 RJW74038.1 - 0.038 11.9 6.8 0.054 11.4 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-Nse PF11789.8 RJW74038.1 - 0.049 13.5 4.3 0.11 12.3 4.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 RJW74038.1 - 0.062 13.3 4.3 0.19 11.8 4.3 1.9 1 1 0 1 1 1 0 Zinc-finger FlaC_arch PF05377.11 RJW74038.1 - 0.064 13.6 2.6 0.37 11.2 2.6 2.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) HAUS6_N PF14661.6 RJW74038.1 - 0.092 12.3 9.9 0.17 11.5 9.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4665 PF15679.5 RJW74038.1 - 0.18 12.4 3.8 0.39 11.4 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) DUF3795 PF12675.7 RJW74038.1 - 0.19 12.2 9.5 0.34 11.4 8.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Tox-ODYAM1 PF15642.6 RJW74038.1 - 0.3 10.0 5.0 0.5 9.3 5.0 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Cep57_CLD_2 PF14197.6 RJW74038.1 - 0.36 10.9 11.9 0.63 10.2 10.9 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DivIVA PF05103.13 RJW74038.1 - 0.47 10.5 11.9 0.88 9.7 11.9 1.4 1 0 0 1 1 1 0 DivIVA protein CLZ PF16526.5 RJW74038.1 - 0.63 10.4 11.9 0.039 14.3 5.6 2.4 2 1 1 3 3 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Aminotran_1_2 PF00155.21 RJW74038.1 - 0.7 9.0 3.0 1.1 8.3 3.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Muted PF14942.6 RJW74038.1 - 0.84 10.0 11.4 1.9 8.8 11.4 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF4407 PF14362.6 RJW74038.1 - 1 8.7 11.1 1.4 8.2 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 RJW74038.1 - 1.2 9.2 4.7 2.4 8.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 RJW74038.1 - 1.3 8.6 10.8 1.9 8.0 10.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 RJW74038.1 - 2.5 5.5 16.7 3.4 5.1 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LMBR1 PF04791.16 RJW74038.1 - 3.1 6.6 5.1 4.4 6.1 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 RJW74038.1 - 3.1 6.3 7.4 4.5 5.8 7.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CREPT PF16566.5 RJW74038.1 - 4 7.6 14.8 1.9 8.6 3.3 2.4 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF5082 PF16888.5 RJW74038.1 - 5.8 7.2 15.4 17 5.7 7.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) SlyX PF04102.12 RJW74038.1 - 5.9 7.6 9.8 9.7 6.9 8.5 2.1 1 1 1 2 2 1 0 SlyX Integrase_H2C2 PF17921.1 RJW74039.1 - 6.9e-09 35.7 0.5 1.5e-08 34.6 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain CUB PF00431.20 RJW74040.1 - 9.1e-15 54.9 0.0 2.1e-08 34.5 0.0 4.0 3 1 1 4 4 4 3 CUB domain zf-C2HC_2 PF13913.6 RJW74043.1 - 7.2e-22 76.8 7.6 6.6e-13 48.2 2.4 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 RJW74043.1 - 1.8e-06 27.7 0.1 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C2H2 PF00096.26 RJW74043.1 - 0.00046 20.5 1.1 0.069 13.6 0.1 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW74043.1 - 0.0009 19.9 3.7 0.11 13.4 0.4 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger DUF2318 PF10080.9 RJW74043.1 - 0.0017 18.4 0.7 0.17 12.0 0.1 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2318) Sgf11 PF08209.11 RJW74043.1 - 0.0084 15.7 2.9 1.4 8.5 0.7 2.4 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) FYDLN_acid PF09538.10 RJW74043.1 - 0.024 15.3 0.6 0.26 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.10 RJW74043.1 - 0.039 14.1 1.4 0.2 11.8 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain ADK_lid PF05191.14 RJW74043.1 - 0.046 13.7 4.7 0.13 12.3 1.7 2.5 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-ACC PF17848.1 RJW74043.1 - 0.065 13.3 0.3 0.14 12.3 0.3 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 RJW74043.1 - 0.095 12.3 0.2 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 RJW74043.1 - 0.28 11.2 1.5 28 4.8 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2256 PF10013.9 RJW74043.1 - 1.2 9.3 5.1 12 6.1 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Transglut_core PF01841.19 RJW74044.1 - 1.7e-08 34.9 0.0 4.3e-06 27.1 0.0 2.8 2 1 0 2 2 2 2 Transglutaminase-like superfamily Peptidase_M8 PF01457.16 RJW74046.1 - 8.9e-19 67.6 0.6 7e-18 64.6 2.1 1.5 2 0 0 2 2 2 1 Leishmanolysin DUF842 PF05811.13 RJW74047.1 - 2.1e-33 114.8 15.7 2.8e-33 114.4 15.7 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Tom5 PF10642.9 RJW74047.1 - 0.17 12.0 0.6 0.38 10.8 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Muted PF14942.6 RJW74047.1 - 0.18 12.1 7.1 0.41 11.0 2.3 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein OmpH PF03938.14 RJW74047.1 - 0.33 11.3 10.1 1.7 8.9 1.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Vanabin-2 PF11437.8 RJW74047.1 - 0.47 10.6 12.8 0.29 11.3 1.6 2.5 1 1 1 2 2 2 0 Vanadium-binding protein 2 Mst1_SARAH PF11629.8 RJW74047.1 - 0.95 9.6 9.6 0.093 12.8 1.9 3.0 3 1 1 4 4 4 0 C terminal SARAH domain of Mst1 GIT_CC PF16559.5 RJW74047.1 - 1.1 9.2 10.8 4.3 7.3 0.8 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Uso1_p115_C PF04871.13 RJW74047.1 - 1.7 9.0 7.5 13 6.2 0.1 2.6 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_2 PF07719.17 RJW74048.1 - 3.6e-08 32.9 11.6 0.067 13.3 0.6 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 RJW74048.1 - 1.4e-05 24.6 2.0 0.0019 17.8 0.0 3.8 5 0 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 RJW74048.1 - 1.5e-05 25.0 2.7 0.1 13.0 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RJW74048.1 - 2.4e-05 23.9 12.8 0.012 15.4 1.4 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RJW74048.1 - 0.001 19.3 3.3 0.0077 16.5 0.3 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RJW74048.1 - 0.0014 19.1 1.3 0.058 13.9 0.1 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RJW74048.1 - 0.0016 18.5 10.1 0.091 13.0 0.5 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW74048.1 - 0.0087 16.8 0.6 20 6.4 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 RJW74048.1 - 0.02 14.9 2.2 0.19 11.8 0.1 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RJW74048.1 - 0.049 13.9 9.2 0.39 11.0 1.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RJW74048.1 - 0.094 13.4 6.2 0.12 13.1 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat APG9 PF04109.16 RJW74050.1 - 3.2e-139 465.1 5.1 4.1e-139 464.7 5.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DGF-1_C PF11040.8 RJW74050.1 - 0.63 10.1 2.8 2.3 8.3 1.7 2.5 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus HNOBA PF07701.14 RJW74051.1 - 1.7e-66 223.9 0.6 3.9e-66 222.7 0.6 1.7 1 0 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 RJW74051.1 - 2.2e-56 190.4 0.0 3.3e-56 189.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 RJW74051.1 - 6.9e-51 172.4 0.3 1.1e-50 171.8 0.3 1.3 1 0 0 1 1 1 1 Haem-NO-binding DUF4890 PF16231.5 RJW74051.1 - 0.097 13.2 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) HVSL PF09749.9 RJW74052.1 - 1.2e-28 100.2 0.1 2.4e-28 99.2 0.1 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein HsdM_N PF12161.8 RJW74052.1 - 0.0095 16.6 0.2 0.018 15.6 0.2 1.4 1 0 0 1 1 1 1 HsdM N-terminal domain ACBP PF00887.19 RJW74054.1 - 1e-25 89.7 0.4 1.6e-25 89.1 0.4 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein RVT_1 PF00078.27 RJW74054.1 - 0.0075 15.8 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chaperone_III PF07824.12 RJW74054.1 - 0.015 15.5 0.1 0.58 10.4 0.1 2.2 2 0 0 2 2 2 0 Type III secretion chaperone domain Hrs_helical PF12210.8 RJW74055.1 - 1.8e-39 134.2 5.3 1.8e-39 134.2 5.3 1.7 1 1 1 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF5082 PF16888.5 RJW74055.1 - 0.075 13.3 2.9 0.13 12.6 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Med2 PF11214.8 RJW74055.1 - 0.1 12.8 5.2 0.21 11.8 4.7 1.7 1 1 1 2 2 2 0 Mediator complex subunit 2 DASH_Spc34 PF08657.10 RJW74055.1 - 0.22 11.3 2.9 0.32 10.8 2.9 1.3 1 1 0 1 1 1 0 DASH complex subunit Spc34 AAA_23 PF13476.6 RJW74055.1 - 0.22 12.0 2.2 0.27 11.7 2.2 1.1 1 0 0 1 1 1 0 AAA domain OmpH PF03938.14 RJW74055.1 - 1 9.7 9.1 1.8 8.9 9.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ACCA PF03255.14 RJW74055.1 - 1.5 8.7 7.7 1.5 8.6 5.9 1.7 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GIY-YIG PF01541.24 RJW74056.1 - 0.036 14.3 0.1 0.097 13.0 0.1 1.7 1 0 0 1 1 1 0 GIY-YIG catalytic domain Ig_3 PF13927.6 RJW74057.1 - 1e-17 64.5 0.0 4.5e-07 30.4 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RJW74057.1 - 1.1e-13 51.1 0.0 4.3e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 RJW74057.1 - 2.4e-09 37.3 0.1 3.4e-08 33.6 0.0 2.8 3 1 0 3 3 3 1 Immunoglobulin V-set domain ig PF00047.25 RJW74057.1 - 4.6e-08 33.1 0.1 0.0012 19.0 0.0 4.3 4 1 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 RJW74057.1 - 4e-07 30.3 0.0 0.05 14.0 0.0 4.1 3 1 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 RJW74057.1 - 0.0003 20.8 0.5 0.0079 16.2 0.0 3.3 4 1 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Cadherin PF00028.17 RJW74058.1 - 9.6e-55 183.0 0.0 3.3e-17 62.7 0.0 7.9 7 1 0 7 7 7 5 Cadherin domain Cadherin_2 PF08266.12 RJW74058.1 - 0.00036 20.3 9.5 9.9 6.1 0.0 7.1 8 0 0 8 8 8 3 Cadherin-like Cation_efflux PF01545.21 RJW74059.1 - 6.1e-48 163.2 5.7 8e-48 162.8 5.7 1.1 1 0 0 1 1 1 1 Cation efflux family L51_S25_CI-B8 PF05047.16 RJW74060.1 - 7.7e-09 35.4 0.1 1.5e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Peroxidase_ext PF11895.8 RJW74060.1 - 0.03 14.3 0.1 2.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Fungal peroxidase extension region Guanylate_cyc PF00211.20 RJW74061.1 - 4.9e-106 352.2 3.9 2.7e-54 183.6 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain GrpE PF01025.19 RJW74061.1 - 0.036 13.7 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 GrpE DUF3425 PF11905.8 RJW74064.1 - 0.021 14.8 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) Ribosomal_L4 PF00573.22 RJW74065.1 - 1.3e-38 132.6 0.2 1.8e-38 132.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 RJW74065.1 - 8.6e-21 73.8 1.6 8.6e-21 73.8 1.6 2.8 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain DUF3913 PF13052.6 RJW74065.1 - 0.003 17.8 0.1 0.047 14.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3913) Nucleopor_Nup85 PF07575.13 RJW74066.1 - 4.5e-45 154.3 0.0 7.9e-41 140.3 0.0 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin CoaE PF01121.20 RJW74068.1 - 1.8e-23 83.2 0.0 3.2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase CTP_transf_like PF01467.26 RJW74068.1 - 7.9e-09 35.8 0.0 4e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like AAA_33 PF13671.6 RJW74068.1 - 0.0017 18.5 0.0 0.0057 16.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RJW74068.1 - 0.0022 17.8 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RJW74068.1 - 0.0037 16.6 0.3 0.016 14.5 0.0 2.1 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 RJW74068.1 - 0.0053 17.3 0.1 0.095 13.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 RJW74068.1 - 0.0096 16.2 0.0 0.025 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RJW74068.1 - 0.018 15.4 0.1 0.043 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 RJW74068.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 RJW74068.1 - 0.058 13.1 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 RJW74068.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Guanylate_kin PF00625.21 RJW74068.1 - 0.12 12.1 0.0 26 4.4 0.0 3.1 3 0 0 3 3 3 0 Guanylate kinase AAA_28 PF13521.6 RJW74068.1 - 0.12 12.6 0.0 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RJW74068.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-H2C2_2 PF13465.6 RJW74070.1 - 1.9e-13 50.2 14.8 7.7e-07 29.3 1.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 RJW74070.1 - 3.6e-13 49.2 17.3 0.00048 20.4 1.1 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RJW74070.1 - 8.4e-09 35.5 14.9 0.0094 16.7 2.2 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RJW74070.1 - 0.00012 21.9 8.4 0.00067 19.6 1.9 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RJW74070.1 - 0.011 16.0 1.9 0.78 10.1 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 RJW74070.1 - 0.2 12.0 0.3 0.39 11.1 0.3 1.5 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2HE PF16278.5 RJW74070.1 - 0.31 11.5 3.9 2.9 8.4 1.0 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 RJW74070.1 - 0.71 10.6 2.4 23 5.7 0.4 2.7 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 RJW74070.1 - 0.75 10.1 8.7 0.72 10.2 2.0 2.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-BED PF02892.15 RJW74070.1 - 1.8 8.6 3.9 1.3 9.1 0.9 2.2 1 1 1 2 2 2 0 BED zinc finger DUF2457 PF10446.9 RJW74070.1 - 3 6.9 9.0 0.13 11.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) zf-AN1 PF01428.16 RJW74070.1 - 5.6 7.2 6.3 29 4.9 1.1 2.9 1 1 1 2 2 2 0 AN1-like Zinc finger TPR_12 PF13424.6 RJW74072.1 - 0.00093 19.4 0.3 0.033 14.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RJW74072.1 - 0.00093 19.8 0.4 3.8 8.6 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 RJW74072.1 - 0.0012 19.1 4.1 2.6 8.6 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RJW74072.1 - 0.0021 17.9 0.4 0.071 13.2 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 RJW74072.1 - 0.0024 17.9 1.8 0.11 12.6 0.3 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RJW74072.1 - 0.0029 17.7 1.0 0.019 15.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RJW74072.1 - 0.037 13.9 1.2 0.037 13.9 1.2 3.8 6 0 0 6 6 6 0 Tetratricopeptide repeat SPOB_a PF14689.6 RJW74072.1 - 0.092 12.5 0.2 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_6 PF13174.6 RJW74072.1 - 1.6 9.5 4.9 1.8 9.4 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF719 PF05334.13 RJW74073.1 - 4e-19 69.6 0.3 4e-19 69.6 0.3 3.1 2 2 0 2 2 2 1 Protein of unknown function (DUF719) DUF2631 PF10939.8 RJW74073.1 - 0.043 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) Peptidase_M8 PF01457.16 RJW74074.1 - 2.7e-19 69.3 0.0 7.2e-19 67.9 0.0 1.6 1 1 0 1 1 1 1 Leishmanolysin PseudoU_synth_1 PF01416.20 RJW74075.1 - 1.3e-12 48.1 0.0 1.5e-11 44.7 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridine synthase Peptidase_M8 PF01457.16 RJW74076.1 - 4.8e-05 22.3 0.0 0.00059 18.6 0.0 2.0 1 1 0 1 1 1 1 Leishmanolysin SprT-like PF10263.9 RJW74076.1 - 0.06 13.2 0.3 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 SprT-like family Tetraspanin PF00335.20 RJW74077.1 - 1.6e-43 149.0 19.8 1.9e-43 148.8 19.8 1.0 1 0 0 1 1 1 1 Tetraspanin family TMEM237 PF15383.6 RJW74077.1 - 1.6 7.8 7.6 11 5.1 0.5 3.0 3 0 0 3 3 3 0 Transmembrane protein 237 PNP_UDP_1 PF01048.20 RJW74078.1 - 8.7e-33 113.5 0.0 1e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily SbcD_C PF12320.8 RJW74079.1 - 0.14 12.4 1.4 0.25 11.7 0.2 2.0 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain MOR2-PAG1_N PF14222.6 RJW74081.1 - 9.4e-144 480.4 4.9 9.4e-144 480.4 4.9 1.5 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 RJW74081.1 - 2.1e-28 99.9 0.2 3.6e-26 92.6 0.0 3.9 3 1 0 3 3 3 1 Cell morphogenesis C-terminal HEAT_2 PF13646.6 RJW74081.1 - 0.0012 19.2 1.5 0.0078 16.6 0.4 2.7 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 RJW74081.1 - 0.045 14.3 0.1 0.38 11.3 0.1 2.8 1 0 0 1 1 1 0 HEAT-like repeat MOR2-PAG1_mid PF14228.6 RJW74081.1 - 1.1 6.9 8.7 8.8 3.8 0.2 4.5 4 1 0 4 4 4 0 Cell morphogenesis central region LRR_6 PF13516.6 RJW74082.1 - 3.8e-08 32.7 35.2 0.12 12.5 0.0 9.9 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 RJW74082.1 - 7.9e-06 26.1 32.8 0.4 11.2 1.6 8.1 6 3 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RJW74082.1 - 1.6e-05 24.8 26.7 2.1 9.2 0.0 10.1 11 0 0 11 11 11 4 Leucine Rich Repeat CAF1C_H4-bd PF12265.8 RJW74083.1 - 1.4e-25 89.3 0.7 2.2e-25 88.7 0.7 1.3 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 RJW74084.1 - 1.7e-25 88.8 14.6 1.1e-06 29.2 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RJW74084.1 - 2.4e-05 24.6 1.1 0.092 13.1 0.0 3.4 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RJW74084.1 - 0.0011 18.9 0.6 0.0091 15.9 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Sugar_tr PF00083.24 RJW74086.1 - 1.2e-32 113.4 25.7 3.6e-23 82.2 11.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RJW74086.1 - 2.4e-27 95.8 42.2 2.1e-17 63.1 25.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RJW74086.1 - 0.0028 16.6 0.1 0.0028 16.6 0.1 3.1 2 2 1 3 3 3 1 MFS_1 like family PNP_UDP_1 PF01048.20 RJW74087.1 - 1.4e-34 119.4 0.0 1.7e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NADH-u_ox-rdase PF10785.9 RJW74088.1 - 0.21 12.3 0.7 4 8.2 0.7 2.5 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit MARVEL PF01284.23 RJW74088.1 - 0.87 9.6 10.4 2.3 8.2 10.4 1.9 1 1 0 1 1 1 0 Membrane-associating domain Cullin PF00888.22 RJW74090.1 - 0.16 10.6 0.0 0.16 10.6 0.0 1.0 1 0 0 1 1 1 0 Cullin family bZIP_1 PF00170.21 RJW74092.1 - 1.3e-07 31.6 11.7 2.2e-07 30.9 11.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RJW74092.1 - 2.2e-06 28.1 7.4 2.2e-06 28.1 7.4 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 RJW74092.1 - 0.00039 20.4 12.5 0.00079 19.4 12.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper SlyX PF04102.12 RJW74092.1 - 0.034 14.8 0.2 0.085 13.5 0.2 1.6 1 0 0 1 1 1 0 SlyX GAS PF13851.6 RJW74092.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Med4 PF10018.9 RJW74092.1 - 0.15 11.7 0.2 0.28 10.8 0.2 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 PKcGMP_CC PF16808.5 RJW74092.1 - 0.22 11.4 0.3 0.4 10.6 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CCD48 PF15799.5 RJW74092.1 - 0.26 9.6 3.8 0.39 9.0 3.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Clonorchis_sinensis-ASM360417v1/GCA_003604175.1_ASM360417v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Clonorchis_sinensis-ASM360417v1/GCA_003604175.1_ASM360417v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Clonorchis_sinensis-ASM360417v1/GCA_003604175.1_ASM360417v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Clonorchis_sinensis-ASM360417v1/GCA_003604175.1_ASM360417v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 20:05:18 2019 # [ok]